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Biomedizinische Technik. Biomedical Engineering

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https://www.readbyqxmd.com/read/28640751/false-spectra-formation-in-the-differential-two-channel-scheme-of-the-laser-doppler-flowmeter
#1
Denis Lapitan, Dmitry Rogatkin, Saydulla Persheyev, Konstantin Kotliar
Noise in the differential two-channel scheme of a classic laser Doppler flowmetry (LDF) instrument was studied. Formation of false spectral components in the output signal due to beating of electrical signals in the differential amplifier was found out. The improved block-diagram of the flowmeter was developed allowing to reduce the noise.
June 22, 2017: Biomedizinische Technik. Biomedical Engineering
https://www.readbyqxmd.com/read/28640750/in-vivo-monitoring-of-infection-via-implantable-microsensors-a-pilot-study
#2
Andrej Ring, Heiko Sorg, Andreas Weltin, Daniel J Tilkorn, Jochen Kieninger, Gerald Urban, Jörg Hauser
The most common complication after implantation of foreign material is infection, leading to implant failure and severe patient discomfort. Smoldering-infections proceed inapparently and might not get verified by radiological diagnostics. Early identification of this type of infection might significantly reduce the rate of complications. Therefore, we manufactured a microsensor strip in a hybrid of thin-film and laminate technology in a wafer-level process. It comprises electrochemical, amperometric microsensors for glucose, oxygen and lactate as well as an integrated reference electrode...
June 22, 2017: Biomedizinische Technik. Biomedical Engineering
https://www.readbyqxmd.com/read/28640749/enamel-shear-bond-strength-of-different-primers-combined-with-an-orthodontic-adhesive-paste
#3
Julia H Seeliger, Ute U Botzenhart, Tomasz Gedrange, Karol Kozak, Lukas Stepien, Monika Machoy
AIM: The aim of this study was a comparison of shear bond strength (SBS) on tooth enamel of different primers combined with the adhesive paste Transbond XT. MATERIALS AND METHODS: Forty bovine teeth were used in order to create 40 test blocks. The blocks were divided into four groups of 10 blocks each: group A - sample primer (SP); group B - Opal Seal (OS); group C - Transbond Plus SEP (TSEP); group D - Transbond XT Primer (TXT). After surface preparation and application of the primer, respectively, two stainless steel brackets were fixed on each tooth by using Transbond XT...
June 22, 2017: Biomedizinische Technik. Biomedical Engineering
https://www.readbyqxmd.com/read/28640748/spike-detection-using-a-multiresolution-entropy-based-method
#4
Sajjad Farashi
Correct interpretation of neural mechanisms depends on the accurate detection of neuronal activities, which become visible as spikes in the electrical activity of neurons. In the present work, a novel entropy based method is proposed for spike detection which employs the fact that transient spike events change the entropy level of the neural time series. In this regard, the time-dependent entropy method can be used for detecting spike times, where the entropy of a selected segment of a neural time series, using a sliding window approach, is calculated and the time of the events are highlighted by sharp peaks in the output of the time-dependent entropy method...
June 22, 2017: Biomedizinische Technik. Biomedical Engineering
https://www.readbyqxmd.com/read/28632492/is-the-location-of-the-signal-intensity-weighted-centroid-a-reliable-measurement-of-fluid-displacement-within-the-disc
#5
Vahid Abdollah, Eric C Parent, Michele C Battié
Degenerated discs have shorter T2-relaxation time and lower MR signal. The location of the signal-intensity-weighted-centroid reflects the water distribution within a region-of-interest (ROI). This study compared the reliability of the location of the signal-intensity-weighted-centroid to mean signal intensity and area measurements. L4-L5 and L5-S1 discs were measured on 43 mid-sagittal T2-weighted 3T MRI images in adults with back pain. One rater analysed images twice and another once, blinded to measurements...
June 20, 2017: Biomedizinische Technik. Biomedical Engineering
https://www.readbyqxmd.com/read/28622141/analysis-of-structural-brain-mri-and-multi-parameter-classification-for-alzheimer-s-disease
#6
Yingteng Zhang, Shenquan Liu
Incorporating with machine learning technology, neuroimaging markers which extracted from structural Magnetic Resonance Images (sMRI), can help distinguish Alzheimer's Disease (AD) patients from Healthy Controls (HC). In the present study, we aim to investigate differences in atrophic regions between HC and AD and apply machine learning methods to classify these two groups. T1-weighted sMRI scans of 158 patients with AD and 145 age-matched HC were acquired from the ADNI database. Five kinds of parameters (i...
June 15, 2017: Biomedizinische Technik. Biomedical Engineering
https://www.readbyqxmd.com/read/28596461/classification-of-pulmonary-pathology-from-breath-sounds-using-the-wavelet-packet-transform-and-an-extreme-learning-machine
#7
Rajkumar Palaniappan, Kenneth Sundaraj, Sebastian Sundaraj, N Huliraj, S S Revadi
BACKGROUND: Auscultation is a medical procedure used for the initial diagnosis and assessment of lung and heart diseases. From this perspective, we propose assessing the performance of the extreme learning machine (ELM) classifiers for the diagnosis of pulmonary pathology using breath sounds. METHODS: Energy and entropy features were extracted from the breath sound using the wavelet packet transform. The statistical significance of the extracted features was evaluated by one-way analysis of variance (ANOVA)...
June 8, 2017: Biomedizinische Technik. Biomedical Engineering
https://www.readbyqxmd.com/read/28525361/engineering-of-biodegradable-magnesium-alloy-scaffolds-to-stabilize-biological-myocardial-grafts
#8
Tobias Schilling, Michael Bauer, Christian Biskup, Axel Haverich, Thomas Hassel
OBJECTIVE: Regenerative bioprostheses are being investigated for replacement of dysfunctional myocardium worldwide. The aim of this study was to develop a degradable magnesium structure to mechanically support the delicate biological grafts during the early remodeling phase. METHODS: Sheets of magnesium alloys (LA33, LA63 and AX30) were manufactured into scaffolds by abrasive water jet cutting. Thereafter, their surface properties, corrosion kinetics, and breakage behaviors were investigated...
May 19, 2017: Biomedizinische Technik. Biomedical Engineering
https://www.readbyqxmd.com/read/28475487/can-somatosensory-electrical-stimulation-relieve-spasticity-in-post-stroke-patients-a-tms-pilot-study
#9
André Salles Cunha Peres, Victor Hugo Souza, João Marcos Yamasaki Catunda, Kelley Cristine Mazzeto-Betti, Taiza Elaine Grespan Santos-Pontelli, Claudia Domingues Vargas, Oswaldo Baffa, Draulio Barros de Araújo, Octávio Marques Pontes-Neto, João Pereira Leite, Marco Antonio Cavalcanti Garcia
Evidence suggests that somatosensory electrical stimulation (SES) may decrease the degree of spasticity from neural drives, although there is no agreement between corticospinal modulation and the level of spasticity. Thus, stroke patients and healthy subjects were submitted to SES (3 Hz) for 30' on the impaired and dominant forearms, respectively. Motor evoked potentials induced by single-pulse transcranial magnetic stimulation were collected from two forearm muscles before and after SES. The passive resistance of the wrist joint was measured with an isokinetic system...
May 5, 2017: Biomedizinische Technik. Biomedical Engineering
https://www.readbyqxmd.com/read/28475486/a-new-method-for-qrs-detection-in-ecg-signals-using-qrs-preserving-filtering-techniques
#10
Tanushree Sharma, Kamalesh K Sharma
Detection of QRS complexes in ECG signals is required for various purposes such as determination of heart rate, feature extraction and classification. The problem of automatic QRS detection in ECG signals is complicated by the presence of noise spectrally overlapping with the QRS frequency range. As a solution to this problem, we propose the use of least-squares-optimisation-based smoothing techniques that suppress the noise peaks in the ECG while preserving the QRS complexes. We also propose a novel nonlinear transformation technique that is applied after the smoothing operations, which equalises the QRS amplitudes without boosting the supressed noise peaks...
May 5, 2017: Biomedizinische Technik. Biomedical Engineering
https://www.readbyqxmd.com/read/28467307/heart-valves-from-polyester-fibers-a-preliminary-6-month-in-vivo-study
#11
Antoine Vaesken, Anne Pelle, Graciela Pavon-Djavid, Jeanne Rancic, Nabil Chakfe, Frederic Heim
Transcatheter aortic valve implantation (TAVI) has become a popular alternative technique to surgical valve replacement for critical patients. Biological valve tissue has been used in TAVI procedures for over a decade, with over 150,000 implantations to date. However, with only 6 years of follow up, little is known about the long-term durability of biological tissue. Moreover, the high cost of tissue harvesting and chemical treatment procedures favor the development of alternative synthetic valve leaflet materials...
May 3, 2017: Biomedizinische Technik. Biomedical Engineering
https://www.readbyqxmd.com/read/28467306/in-service-characterization-of-a-polymer-wick-based-quasi-dry-electrode-for-rapid-pasteless-electroencephalography
#12
Paulo Pedrosa, Patrique Fiedler, Vanessa Pestana, Beatriz Vasconcelos, Hugo Gaspar, Maria H Amaral, Diamantino Freitas, Jens Haueisen, João M Nóbrega, Carlos Fonseca
A novel quasi-dry electrode prototype, based on a polymer wick structure filled with a specially designed hydrating solution is proposed for electroencephalography (EEG) applications. The new electrode does not require the use of a conventional electrolyte paste to achieve a wet, low-impedance scalp contact. When compared to standard commercial Ag/AgCl sensors, the proposed wick electrodes exhibit similar electrochemical noise and potential drift values. Lower impedances are observed when tested in human volunteers due to more effective electrode/skin contact...
May 3, 2017: Biomedizinische Technik. Biomedical Engineering
https://www.readbyqxmd.com/read/28467305/breast-sentinel-lymph-node-biopsy-with-imaging-towards-minimally-invasive-surgery
#13
REVIEW
Fredrick Johnson Joseph, Alexander van Oepen, Michael Friebe
Breast sentinel lymph nodes are still commonly assessed through complete lymph node dissections, which is a time-consuming and radical approach because the nodes are difficult to identify. To prevent false diagnosis and achieve accurate results, minimally invasive, image-guided procedures are applied and constantly improved. The purpose of this paper is to present the currently used imaging modalities ultrasound, fluorescence, single-photon emission computed tomography (SPECT), magnetic resonance imaging (MRI) and hybrid imaging methods and comparing their effectiveness for breast sentinel lymph node biopsy...
May 3, 2017: Biomedizinische Technik. Biomedical Engineering
https://www.readbyqxmd.com/read/28453437/umbilical-cord-as-human-cell-source-for-mitral-valve-tissue-engineering-venous-vs-arterial-cells
#14
Axel Malischewski, Ricardo Moreira, Luis Hurtado, Valentine Gesché, Thomas Schmitz-Rode, Stefan Jockenhoevel, Petra Mela
Around 2% of the population in developed nations are affected by mitral valve disease and available valvular replacements are not designed for the atrioventricular position. Recently our group developed the first tissue-engineered heart valve (TEHV) specifically designed for the mitral position - the TexMi valve. The valve recapitulates the main components of the native valve, i.e. annulus, asymmetric leaflets and the crucial chordae tendineae. In the present study, we evaluated the human umbilical cord as a clinically applicable cell source for the TexMi valve...
April 28, 2017: Biomedizinische Technik. Biomedical Engineering
https://www.readbyqxmd.com/read/28448270/a-new-in-vitro-spine-test-rig-to-track-multiple-vertebral-motions-under-physiological-conditions
#15
Agnes Beckmann, Christian Herren, Marion Mundt, Jan Siewe, Philipp Kobbe, Rolf Sobottke, Hans-Christoph Pape, Marcus Stoffel, Bernd Markert
In vitro pure moment spine tests are commonly used to analyse surgical implants in cadaveric models. Most of the tests are performed at room temperature. However, some new dynamic instrumentation devices and soft tissues show temperature-dependent material properties. Therefore, the aim of this study is to develop a new test rig, which allows applying pure moments on lumbar spine specimens in a vapour-filled chamber at body temperature. As no direct sight is given in the vapour-filled closed chamber, a magnetic tracking (MT) system with implantable receivers was used...
April 27, 2017: Biomedizinische Technik. Biomedical Engineering
https://www.readbyqxmd.com/read/28384099/a-decomposition-model-and-voxel-selection-framework-for-fmri-analysis-to-predict-neural-response-of-visual-stimuli
#16
Savita V Raut, Dinkar M Yadav
This paper presents an fMRI signal analysis methodology using geometric mean curve decomposition (GMCD) and mutual information-based voxel selection framework. Previously, the fMRI signal analysis has been conducted using empirical mean curve decomposition (EMCD) model and voxel selection on raw fMRI signal. The erstwhile methodology loses frequency component, while the latter methodology suffers from signal redundancy. Both challenges are addressed by our methodology in which the frequency component is considered by decomposing the raw fMRI signal using geometric mean rather than arithmetic mean and the voxels are selected from EMCD signal using GMCD components, rather than raw fMRI signal...
April 6, 2017: Biomedizinische Technik. Biomedical Engineering
https://www.readbyqxmd.com/read/28593869/a-mock-heart-engineered-with-helical-aramid-fibers-for-in-vitro-cardiovascular-device-testing
#17
So-Hyun Jansen-Park, Po-Lin Hsu, Indra Müller, Ulrich Steinseifer, Dirk Abel, Rüdiger Autschbach, Rolf Rossaint, Thomas Schmitz-Rode
Mock heart circulation loops (MHCLs) serve as in-vitro platforms to investigate the physiological interaction between circulatory systems and cardiovascular devices. A mock heart (MH) engineered with silicone walls and helical aramid fibers, to mimic the complex contraction of a natural heart, has been developed to advance the MHCL previously developed in our group. A mock aorta with an anatomical shape enables the evaluation of a cannulation method for ventricular assist devices (VADs) and investigation of the usage of clinical measurement systems like pressure-volume catheters...
April 4, 2017: Biomedizinische Technik. Biomedical Engineering
https://www.readbyqxmd.com/read/28157688/pattern-recognition-of-enrichment-levels-of-selex-based-candidate-aptamers-for-human-c-reactive-protein
#18
Xinliang Yu, Ruqin Yu, Xiaohai Yang
Selecting aptamers for human C-reactive protein (CRP) would be of critical importance in predicting the risk for cardiovascular disease. The enrichment level of DNA aptamers is an important parameter for selecting candidate aptamers for further affinity and specificity determination. This paper is the first report on pattern recognition used for CRP aptamer enrichment levels in the systematic evolution of ligands by exponential enrichment (SELEX) process, by applying structure-activity relationship models. After generating 10 rounds of graphene oxide (GO)-SELEX and 1670 molecular descriptors, eight molecular descriptors were selected and five latent variables were then obtained with principal component analysis (PCA), to develop a support vector classification (SVC) model...
May 24, 2017: Biomedizinische Technik. Biomedical Engineering
https://www.readbyqxmd.com/read/27574854/computer-assisted-evaluation-of-plate-osteosynthesis-of-diaphyseal-femur-fracture-considering-interfragmentary-movement-a-finite-element-study
#19
Claudia Wittkowske, Stefan Raith, Maximilian Eder, Alexander Volf, Jan S Kirschke, Benjamin König, Christoph Ihle, Hans-Günther Machens, Stefan Döbele, Laszlo Kovacs
A semi-automated workflow for evaluation of diaphyseal fracture treatment of the femur has been developed and implemented. The aim was to investigate the influence of locking compression plating with diverse fracture-specific screw configurations on interfragmentary movements (IFMs) with the use of finite element (FE) analysis. Computed tomography (CT) data of a 22-year-old non-osteoporotic female were used for patient specific modeling of the inhomogeneous material properties of bone. Hounsfield units (HU) were exported and assigned to elements of a FE mesh and converted to mechanical properties such as the Young's modulus followed by a linear FE analysis performed in a semi-automated fashion...
May 24, 2017: Biomedizinische Technik. Biomedical Engineering
https://www.readbyqxmd.com/read/27567597/accuracy-of-leg-alignment-measurements-from-antero-posterior-radiographs
#20
Rahul Khare, Branislav Jaramaz
After a knee replacement procedure, postoperative radiological assessment is carried out to evaluate outcome and predict procedure success. For this assessment, long-standing load-bearing antero-posterior radiographs are used to carry out manual identification of anatomic landmarks. These landmarks are subsequently used to estimate leg alignment. The positions of the landmarks in the radiographs are affected by the patient pose and the X-ray projection center. Although there is some past work exploring the impact of patient pose on the landmarks in the radiographs, there is no previous work on the impact of the X-ray projection center on the estimated leg alignment...
May 24, 2017: Biomedizinische Technik. Biomedical Engineering
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