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Biomedizinische Technik. Biomedical Engineering

Aleksandar Peulić, Tijana Šušteršič, Miodrag Peulić
This paper presents the improved technique for classification of the type of lumbar discus hernia based on fuzzy logic. The reduced mobility of the foot is one of the symptoms of the disease that occurs because of the displaced discs in the space of two vertebrae. This fact was used for non-invasive discus hernia diagnosis by measuring force values from four sensors placed on both feet (first, second and fourth metatarsal head as well as the heel). Hardware and software systems were constructed for the doctor to perform the measurements and have a graphical representation during the measuring procedure...
October 6, 2018: Biomedizinische Technik. Biomedical Engineering
Babak Bazrafshan, Ahmad Koujan, Frank Hübner, Christian Leithäuser, Norbert Siedow, Thomas J Vogl
The purpose of this study was to develop a thermometry software tool for temperature monitoring during laser-induced interstitial thermotherapy (LITT). C++ programming language and several libraries including DICOM Toolkit, Grassroots DICOM library, Insight Segmentation and Registration Toolkit, Visualization Toolkit and Quasar Toolkit were used. The software's graphical user interface creates windows displaying the temperature map and the coagulation extent in the tissue, determined by the magnetic resonance imaging (MRI) thermometry with the echo planar imaging sequence and a numerical simulation based on the radiation and heat transfer in biological tissues, respectively...
September 22, 2018: Biomedizinische Technik. Biomedical Engineering
Neelamegam Devarasu, Gnanou Florence Sudha
A noninvasive investigation to ascertain the hematocrit (HCT) or packed cell volume (PCV) was conducted on 44 hospitalized dengue hemorrhagic fever (DHF) subjects, male and female aged between 3 and 14 years using bioelectrical impedance analysis (BIA). Among the 44 subjects, 30 subjects were confirmed to be non-structural protein-1 (NS1) positive at the time of admission, whose blood investigations such as HCT level, platelet (PLT) count, aspartate aminotransferase (AST) level and alanine aminotransferase (ALT) level were taken for the classification of risk as low risk (LR) and high risk (HR) DHF...
September 21, 2018: Biomedizinische Technik. Biomedical Engineering
Jan Osmers, Michael Sorg, Andreas Fischer
Motivation Glaucoma is currently the most common irreversible cause of blindness worldwide. A significant risk factor is an individually increased intraocular pressure (IOP). A precise measurement method is needed to determine the IOP in order to support the diagnosis of the disease and to monitor the outcome of the IOP reduction as a medical intervention. A handheld device is under development with which the patient can perform self-measurements outside the clinical environment. Method For the measurement principle of the self-tonometer the eye is acoustically excited to oscillate, which is analyzed and attributed to the present IOP...
September 19, 2018: Biomedizinische Technik. Biomedical Engineering
Nurul Salwani Mohamad Saadon, Nur Azah Hamzaid, Nazirah Hasnan, Muhammad Afiq Dzulkifli, Glen M Davis
Repetitive electrically-evoked muscle contraction leads to accelerated muscle fatigue. This study assessed electrically-evoked fatiguing muscle with changes to mechanomyography root mean square percentage (%RMS-MMG) and tissue saturation index (%TSI) in extensor carpi radialis. Forty healthy volunteers (n=40) performed repetitive electrical-evoked wrist extension to fatigue and results were analyzed pre- and post-fatigue, i.e. 50% power output (%PO) drop. Responses of %PO, %TSI and %RMS-MMG were correlated while the relationships between %RMS-MMG and %TSI were investigated using linear regression...
September 19, 2018: Biomedizinische Technik. Biomedical Engineering
ChangMin Choi, Se-Han Lee, DongGeon Lee, SoungKyun Hong, SeungHyeon Pyo, SuHo Park, Kyeongbong Lee, GyuChang Lee
The elderly population in many countries has been rising rapidly, and falls are a serious event many elderly people experience. Assistive equipment is actively used to reduce falls among elderly people. Popular types of assistive equipment include canes, electric wheelchairs, and wheeled walkers. Wheeled walkers support the body of elderly people, making their gait comfortable as they age or recover from injuries. Wheeled walkers may be equipped with hand brakes; however, frail older people may experience difficulty using such hand brakes, as they require force to operate...
September 19, 2018: Biomedizinische Technik. Biomedical Engineering
Birgit Huber, Eva Hoch, Iván Calderon, Kirsten Borchers, Petra J Kluger
Size and function of bioartificial tissue models are still limited due to the lack of blood vessels and dynamic perfusion for nutrient supply. In this study, we evaluated the use of cytocompatible methacryl-modified gelatin for the fabrication of a hydrogel-based tube by dip-coating and subsequent photo-initiated cross-linking. The wall thickness of the tubes and the diameter were tuned by the degree of gelatin methacryl-modification and the number of dipping cycles. The dipping temperature of the gelatin solution was adjusted to achieve low viscous fluids of approximately 0...
September 18, 2018: Biomedizinische Technik. Biomedical Engineering
Bennet Hensen, Urte Kägebein, Marcel Gutberlet, Kristina I Ringe, Van Dai Vo-Chieu, Daniel Stucht, Oliver Speck, Ralf Vick, Frank Wacker, Enrico Pannicke
No abstract text is available yet for this article.
September 6, 2018: Biomedizinische Technik. Biomedical Engineering
Steffi Grohmann, Manuela Menne, Diana Hesse, Sabine Bischoff, René Schiffner, Michael Diefenbeck, Klaus Liefeith
No abstract text is available yet for this article.
September 3, 2018: Biomedizinische Technik. Biomedical Engineering
Nico Hoffmann, Yordan Radev, Edmund Koch, Uwe Petersohn, Gerald Steiner, Matthias Kirsch
The resection of brain tumor requires a precise distinction between eloquent areas of the brain and pathological tumor tissue in order to improve the extent of resection as well as the patient's progression free survival time. In this study, we discuss mathematical tools necessary to recognize neural activity using thermal imaging cameras. The main contribution to thermal radiation of the exposed human cortex is regional cerebral blood flow (CBF). In fact, neurovascular coupling links neural activity to changes in regional CBF which in turn affects the cortical temperature...
October 25, 2018: Biomedizinische Technik. Biomedical Engineering
Tobias Heimpold, Frank Reifegerste, Stefan Drechsel, Jens Lienig
Hyperspectral imaging (HSI) has become a sophisticated technique in modern applications such as food analyses, recycling technology, medicine, pharmacy and forensic science. It allows one to analyse both spatial and spectral information from an object. But hyperspectral cameras are still expensive due to their extended wavelength range. The development of new light-emitting diodes (LED) in the recent past enables another approach to HSI using a monochrome camera in combination with a LED-based illumination...
October 25, 2018: Biomedizinische Technik. Biomedical Engineering
Werner Nahm, Christoph Hornberger, Ute Morgenstern, Stephan B Sobottka
No abstract text is available yet for this article.
October 25, 2018: Biomedizinische Technik. Biomedical Engineering
Fang Chen, Jan Müller, Jens Müller, Juliane Müller, Elisa Böhl, Matthias Kirsch, Ronald Tetzlaff
The intraoperative identification of normal and anomalous brain tissue can be disturbed by pulsatile brain motion and movements of the patient and surgery devices. The performance of four motion correction methods are compared in this paper: Two intensity-based, applying optical flow algorithms, and two feature-based, which take corner features into account to track brain motion. The target registration error with manually selected marking points and the temporal standard deviation of intensity were analyzed in the evaluation...
October 25, 2018: Biomedizinische Technik. Biomedical Engineering
Wenke Markgraf, Philipp Feistel, Christine Thiele, Hagen Malberg
The lack of donor grafts is a severe problem in transplantation medicine. Hence, the improved preservation of existing and the usage of organs that were deemed untransplantable is as urgent as ever. The development of novel preservation techniques has come into focus. A promising alternative to traditional cold storage is normothermic machine perfusion (NMP), which provides the benefit of improving the organs' viability and of assessing the organs' status under physiological conditions. For this purpose, methods for evaluating organ parameters have yet to be developed...
October 25, 2018: Biomedizinische Technik. Biomedical Engineering
Claudia Sicher, Rico Rutkowski, Stine Lutze, Sebastian von Podewils, Thomas Wild, Markus Kretching, Georg Daeschlein
There is a lack of imaging tools for the evaluation of spatial alterations in microcirculation including blood oxygen saturation and hemoglobin distribution but recent innovative developments in hyperspectral technology may offer a solution. We examined different hemodynamic disorders in patients suffering from scleroderma, Dupuytren surgery, chronic foot ulcera and skin infections. Superficial and deeper blood oxygen saturation, hemoglobin distribution and water content were determined using hyperspectral imaging (HSI)...
October 25, 2018: Biomedizinische Technik. Biomedical Engineering
Florian Tetschke, Lars Kirsten, Jonas Golde, Julia Walther, Roberta Galli, Edmund Koch, Christian Hannig
The detection of the beginning demineralization process of dental hard tissue remains a challenging task in dentistry. As an alternative to bitewing radiographs, optical and spectroscopic technologies showed promising results for caries diagnosis. The aim of the present work is to give an overview of optical and spectroscopic properties of healthy and carious human teeth in vitro by means of Raman spectroscopy (RS), optical coherence tomography (OCT) and hyperspectral imaging (HSI). OCT was able to represent microstructural changes below the enamel surface and revealed increased scattering for white spot lesions and a white scattering trail for deeper lesions...
October 25, 2018: Biomedizinische Technik. Biomedical Engineering
Amadeus Holmer, Jörg Marotz, Philip Wahl, Michael Dau, Peer W Kämmerer
Blood perfusion is the supply of tissue with blood, and oxygen is a key factor in the field of minor and major wound healing. Reduced perfusion of a wound bed or transplant often causes various complications. Reliable methods for an objective evaluation of perfusion status are still lacking, and insufficient perfusion may remain undiscovered, resulting in chronic processes and failing transplants. Hyperspectral imaging (HSI) represents a novel method with increasing importance for clinical practice. Therefore, methods, software and algorithms for a new HSI system are presented which can be used to observe tissue oxygenation and other parameters that are of importance in supervising healing processes...
October 25, 2018: Biomedizinische Technik. Biomedical Engineering
Sebastian Zaunseder, Alexander Trumpp, Daniel Wedekind, Hagen Malberg
Over the last few years, the contactless acquisition of cardiovascular parameters using cameras has gained immense attention. The technique provides an optical means to acquire cardiovascular information in a very convenient way. This review provides an overview on the technique's background and current realizations. Besides giving detailed information on the most widespread application of the technique, namely the contactless acquisition of heart rate, we outline further concepts and we critically discuss the current state...
October 25, 2018: Biomedizinische Technik. Biomedical Engineering
Georg Daeschlein, Rico Rutkowski, Stine Lutze, Sebastian von Podewils, Claudia Sicher, Thomas Wild, Hans-Robert Metelmann, Thomas von Woedkte, Michael Jünger
An important clinical potential of cold atmospheric plasma (CAP) lies in tumor and wound treatment, whereby the last-mentioned is well-referenced already. However, the underlying mechanisms of improved wound healing have not been sufficiently clarified yet, in particular the influence of CAP on microcirculation. Hyperspectral imaging (HSI) enables the visualization of microcirculation of large tissue areas, thus this technique seems to be a candidate to examine CAP effects on perfusion and oxygen saturation in wounds...
October 25, 2018: Biomedizinische Technik. Biomedical Engineering
Axel Kulcke, Amadeus Holmer, Philip Wahl, Frank Siemers, Thomas Wild, Georg Daeschlein
Worldwide, chronic wounds are still a major and increasing problem area in medicine with protracted suffering of patients and enormous costs. Beside conventional wound treatment, for instance kinds of oxygen therapy and cold plasma technology have been tested, providing an improvement in the perfusion of wounds and their healing potential, but these methods are unfortunately not sufficiently validated and accepted for clinical practice to date. Using hyperspectral imaging technology in the visible (VIS) and near infrared (NIR) region with high spectral and spatial resolution, perfusion parameters of tissue and wounds can be determined...
October 25, 2018: Biomedizinische Technik. Biomedical Engineering
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