Read by QxMD icon Read

Acta Neurobiologiae Experimentalis

Pilani Nkomozepi, Pedzisai Mazengenya, Amadi O Ihunwo
Most avian neurogenesis studies have previously focused on the song control system and little attention has been given to non‑song birds. The objective of this study was to assess changes in neurogenesis associated with post‑hatching age (3‑12 weeks) in the Japanese quail brain using proliferating cell nuclear antigen (PCNA) and doublecortin (DCX) immunohistochemistry. PCNA‑immunoreactive (ir) cells were observed mainly in the olfactory bulb ventricular zone, telencephalic ventricular zones and cerebellum...
2018: Acta Neurobiologiae Experimentalis
Miroslaw Wyczesany, Tomasz S Ligeza, Agnieszka Tymorek, Agnieszka Adamczyk
In the study we investigated how current mood affects spontaneous perceptual processes of neutral stimuli of low‑arousal, unrelated to any specific task. Two separate but similar procedures were carried out: one using functional magnetic resonance imaging (fMRI), the other using electroencephalography based source localization. In both experiments, sessions of passive viewing of neutral pictures were preceded by either a negative or positive mood induction. In response to neutral stimuli, we observed higher activation of visual areas after positive mood induction and lower activations in medial prefrontal and right frontotemporal regions after negative mood induction...
2018: Acta Neurobiologiae Experimentalis
Algis Bertulis, Tadas Surkys, Arūnas Bielevičius
In the present visual psychophysical study, the Oppel‑Kundt and and Müller‑Lyer illusion magnitudes were measured separately (by single figures) and in combination (by two patterns superposed spatially). Data for 30 subjects revealed extensive variability both for the separate and combined illusion strength. Nevertheless, the effect of addition of the perceived length distortions was established. The combined illusions were significantly stronger than the separate ones. Dynamics of the misperceptions summation was studied by varying length of the Müller‑Lyer wings in the superposed stimuli...
2018: Acta Neurobiologiae Experimentalis
Libor Cerny, Jan Vokral, Olga Dlouha
Problems with hearing aids, particularly with regard to speech intelligibility in the presence of noise, are commonly reported by older individuals in everyday practice. The main goal of this study was to measure differences in speech intelligibility between older and younger people and to establish how speech intelligibility in competitive noise differs between younger and older populations with similar hearing status. More than 400 persons were tested using the Czech Test of Sentence Intelligibility in Babble Noise and divided into younger (40-65 years) and older (66-85 years) age groups...
2018: Acta Neurobiologiae Experimentalis
Yulia V Dobryakova, Olga Y Ivanova, Vladimir A Markevich
Muscarinic acetylcholine receptors (mAChR) are known to be related to learning and memory processes. Inactivation of mAChR by cholinergic antagonists have been shown to produce amnesia in a variety of behavioral tasks. In this study, we investigated the role of M1 and M2 AChR on passive avoidance learning and plasticity of synapses formed by Schaffer collaterals in freely moving rats. Experiments were performed using Wistar male rats. Seven days before testing, a recording electrode was lowered in the CA1 region under chloral hydrate anaesthesia to record the field excitatory postsynaptic potential (fEPSP) in response to Schaffer collateral stimulation...
2018: Acta Neurobiologiae Experimentalis
Hanna B Cygan, Hanna Okuniewska, Katarzyna Jednoróg, Artur Marchewka, Marek Wypych, Anna Nowicka
The ability to "read" the information about facial identity, expressed emotions, and intentions is crucial for non‑verbal social interaction. Neuroimaging and clinical studies consequently link face perception with fusiform gyrus (FG) and occipital face area (OFA) activity. Here we investigated face processing in an adult, patient PK, diagnosed with both high functioning autism spectrum disorder (ASD) and developmental prosopagnosia (DP). Both disorders have a significant impact on face perception and recognition, thus creating a unique neurodevelopmental condition...
2018: Acta Neurobiologiae Experimentalis
Mateusz Rusiniak, Andrzej Wróbel, Katarzyna Cieśla, Agnieszka Pluta, Monika Lewandowska, Joanna Wójcik, Piotr Henryk Skarżyński, Tomasz Wolak
Alpha rhythm, described by Hans Berger, is mainly recorded from the occipital cortex (OCC) of relaxed subjects with their eyes closed.Early studies indicated the thalamo‑cortical circuit as the origin of alpha rhythm. Recent works suggest an additional relationship between alpha rhythm and the Default Mode Network (DMN). We simultaneously recorded electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) signals in 36 young males asked to alternately close and open their eyes in 30‑s blocks...
2018: Acta Neurobiologiae Experimentalis
Inna V Vereshchaka, Andriy V Maznychenko, Olena P Mankivska, Volodymyr O Maisky, Oleh V Vlasenko, Olexandr V Dovgan', Olga L Ocheretna, Tomasz Tomiak, Alexander I Kostyukov
We investigated neuronal activation of the rat intermediolateral (IML) nucleus of the thoracolumbar spinal cord, initiated by Achilles tendon vibration, after intramuscular (m. triceps surae) administration of 7‑nitroindazole (7‑NI) or L‑arginine (LA). The spindle afferent response to vibratory stimuli induced a distinct bilateral increase in the activation of c‑Fos immunoreactivity in the spinal neurons in three groups of rats (tendon‑vibrated, tendon‑vibrated + 7‑NI and tendon‑vibrated + LA)...
2018: Acta Neurobiologiae Experimentalis
Marta Grochowska, Marcin Wojnar, Marek Radkowski
The purpose of this review is to summarize current knowledge about the gut microbiota in neuropsychiatric disorders. It is estimated that the human gut is colonized by up to 1018 microorganisms, mostly anaerobic bacteria. The gut microbiome is responsible for multiple functions, e.g. tightness of the intestine barrier, digestion and absorption. The correlation between gut dysbiosis and development of psychiatric, autoimmune and allergic diseases as well as bidirectional communication between brain and gut microflora have been shown...
2018: Acta Neurobiologiae Experimentalis
Shahram Oliaei, Mohammed N Ashtiani, Kamran Azma, Sandra Saidi, Mahmood-Reza Azghani
Standing on an unstable platform requires continuous effort of the neuro‑musculoskeletal system. The aim of the present study is to evaluate the ability to remain standing on an unstable platform at different levels of postural and cognitive difficulty. Healthy young males stood in the sagittal plane on an unstable platform supported by a pair of springs with modifiable stiffness. The balance test also assessed different levels of vision and cognitive function. Linear and nonlinear metrics of standing, based on motion captured kinematic data, were assessed to analyze the stability of standing...
2018: Acta Neurobiologiae Experimentalis
Raheleh Kheirbakhsh, Mahnaz Haddadi, Ahad Muhammadnejad, Alireza Abdollahi, Farshad Shahi, Behzad Amanpour-Gharaei, Azadeh Abrahim-Habibi, Tahereh Barati, Saeid Amanpour
Alzheimer's disease (AD) is a mental impairment and neural degeneration which causes progressive loss of memory and cognitive functions. This age‑dependent illness is associated with extracellular amyloid plaques accumulation and twisted neurofibrillary tangles. Amyloid plaques are experimentally generated in animal models in order to investigate the disease process. In this study, we followed a rat model of AD for over a year. Wistar rats were divided randomly into two groups as control group (surgery without injection Aβ), and experimental group (two‑sided intrahippocampal amyloid‑beta injection into hippocampus)...
2018: Acta Neurobiologiae Experimentalis
Bruno A Marichal-Cancino, Alfonso Fajardo-Valdez, Alejandra E Ruiz-Contreras, Mónica Méndez-Díaz, Oscar Prospéro-García
Endocannabinoids (eCBs) are involved in the hippocampal mechanisms of spatial learning and memory in rats. Although eCBs exert many of their actions on spatial learning and memory via CB1 receptors, the putative cannabinoid receptor GPR55 (expressed in the hippocampus, cortex, forebrain, cerebellum and striatum) seems to be also involved. To investigate the potential role of GPR55 in spatial learning and memory, Wistar rats received bilateral infusions of lysophosphatidylinositol (LPI, GPR55‑agonist) into the hippocampus 5‑minutes before training‑phase in the Barnes‑maze (BM)...
2018: Acta Neurobiologiae Experimentalis
Kedarlal Sharma, Juhi Singh, Emma E Frost, Prakash P Pillai
avMethyl‑CpG binding protein 2 (MeCP2) is an epigenetic regulator, which preferentially binds to methylated CpG dinucleotides in DNA. MeCP2 mutations have been linked to Rett syndrome, a neurodevelopmental disorder characterized by severe intellectual disability in females. Earlier studies indicated that loss of MeCP2 function in neuronal cells was the sole cause of Rett syndrome. Subsequent studies have linked MeCP2 expression in CNS glial cells to Rett syndrome pathogenesis. In this review, we have discussed the role of MeCP2 in glial subtypes, astrocytes, oligodendrocytes and microglia, and how loss of MeCP2 function in these cells has a profound influence on both glial and neuronal function...
2018: Acta Neurobiologiae Experimentalis
Geir Bjørklund, Janet K Kern, Mauricio A Urbina, Khaled Saad, Amira A El-Houfey, David A Geier, Salvatore Chirumbolo, Mark R Geier, Jyutika A Mehta, Jan Aaseth
Cerebral hypoperfusion, or insufficient blood flow in the brain, occurs in many areas of the brain in patients diagnosed with autism spectrum disorder (ASD). Hypoperfusion was demonstrated in the brains of individuals with ASD when compared to normal healthy control brains either using positron emission tomography (PET) or single‑photon emission computed tomography (SPECT). The affected areas include, but are not limited to the: prefrontal, frontal, temporal, occipital, and parietal cortices; thalami; basal ganglia; cingulate cortex; caudate nucleus; the limbic system including the hippocampal area; putamen; substantia nigra; cerebellum; and associative cortices...
2018: Acta Neurobiologiae Experimentalis
Cezar Octavian Morosanu, Razvan Lucian Jurca, Larisa Simonca, Roxana Flavia Ilies, Remus Moldovan, Ioan Stefan Florian, Gabriela Adriana Filip
Cerebral hemispherectomy is a neurosurgical procedure that involves surgically removing one hemisphere of the brain, used as a therapeutic option in severe cases of intractable epilepsy. Several animal models have contributed to our understanding of the underlying neuromechanisms. The review was based on a PubMed search using the terms "hemispherectomy" and "mouse" or "rat" or "rodent", with no limitation of year of study or language. We identified a series of elements that were collected and analyzed that add up to our contemporary knowledge of this procedure...
2018: Acta Neurobiologiae Experimentalis
Weronika Rzepnikowska, Andrzej Kochański
In 2002 a series of mutations in the GDAP1 gene were reported in patients suffering from Charcot‑Marie‑Tooth disease manifesting as early-onset, progressive distal‑muscle wasting and weakness. The molecular etiology of Charcot‑Marie‑Tooth ‑GDAP1 disease has been elucidated but its pathogenesis remains unclear, especially given the seemingly contradictory function of the GDAP1 protein. Expression of GDAP1 is observed almost exclusively in neuronal cells, however, the GDAP1 protein is present in mitochondria, where it plays a role in fission, a ubiquitous process occurring in all cells...
2018: Acta Neurobiologiae Experimentalis
Nurhan Enginar, Asiye Nurten, Aslı Zengin Türkmen, Gül İpek Gündoğan, Zeynep Güneş Özünal
Prolonged or repeated seizures have been shown to cause spontaneous recurrent seizures, increased anxiety‑related behavior, locomotor hyperactivity, impaired functions of learning and memory, and neuronal damage in the hippocampus and other brain regions in animals. Mice and rats treated with antimuscarinic drugs after fasting for two days or less develop convulsions after being allowed to eat ad libitum. To address whether such behavioral and neuroanatomic changes occur following these convulsions, mice treated i...
2017: Acta Neurobiologiae Experimentalis
Bettina Moritz, Marcelo Liborio Schwarzbold, Ricardo Guarnieri, Alexandre Paim Diaz, Ana Lúcia S Rodrigues, Alcir Luiz Dafre
Objective Given that the literature data indicates that ascorbic acid may have an anxiolytic effect, we hypothesized that a single oral administration of ascorbic acid could acutely affect emotional states. Methods The effects of acid ascorbic supplementation on anxiety and other emotional states were evaluated by the State‑Trait Anxiety Inventory (STAI), and Visual Analogue Mood Scale (VAMS). Immediately before, and 2 hours after receiving a single ascorbic acid dose (1000 mg) or placebo, 142 graduate students were evaluated by the STAI and VAMS in a randomized, double‑blind, placebo‑controlled trial...
2017: Acta Neurobiologiae Experimentalis
Elka Popova, Petia Kupenova
Functional interactions between serotoninergic and GABAergic systems in the vertebrate retina are largely unknown. In this study, the effects of isolated or combined stimulation of the serotonin receptors (with 100 μM serotonin) and ionotropic GABAA and GABAC receptors (with 5 mM TACA) on the electroretinographic (ERG) ON (b‑wave) and OFF (d‑wave) responses were investigated in frog eyecup preparations. It was found that serotonin alone produced a significant enhancement of the b‑ and d‑wave amplitude, while TACA alone caused its marked diminution...
2017: Acta Neurobiologiae Experimentalis
Juraj Blaško, Eva Szekiova, Lucia Slovinska, Jozef Kafka, Dasa Cizkova
Despite strong efforts in the field, spinal cord trauma still belongs among the untreatable neurological conditions at present. Given the complexity of the nervous system, an effective therapy leading to complete recovery has still not been found. One of the potential tools for supporting tissue regeneration may be found in mesenchymal stem cells, which possess anti‑inflammatory and trophic factor‑producing properties. In the context of transplantations, application of degradable biomaterials which could form a supportive environment and scaffold to bridge the lesion area represents another attractive strategy...
2017: Acta Neurobiologiae Experimentalis
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"