journal
MENU ▼
Read by QxMD icon Read
search

Acta Neurobiologiae Experimentalis

journal
https://www.readbyqxmd.com/read/29694342/effects-of-postural-and-cognitive-difficulty-levels-on-the-standing-of-healthy-young-males-on-an-unstable-platform
#1
Shahram Oliaei, Mohammed N Ashtiani, Kamran Azma, Sandra Saidi, Mahmood-Reza Azghani
Standing on an unstable platform requires continuous effort of the neuro‑musculoskeletal system. The aim of the present study is to evaluate the ability to remain standing on an unstable platform at different levels of postural and cognitive difficulty. Healthy young males stood in the sagittal plane on an unstable platform supported by a pair of springs with modifiable stiffness. The balance test also assessed different levels of vision and cognitive function. Linear and nonlinear metrics of standing, based on motion captured kinematic data, were assessed to analyze the stability of standing...
2018: Acta Neurobiologiae Experimentalis
https://www.readbyqxmd.com/read/29694341/long%C3%A2-term-behavioral-histological-biochemical-and-hematological-evaluations-of-amyloid-beta%C3%A2-induced-alzheimer-s-disease-in-rat
#2
Raheleh Kheirbakhsh, Mahnaz Haddadi, Ahad Muhammadnejad, Alireza Abdollahi, Farshad Shahi, Behzad Amanpour-Gharaei, Azadeh Abrahim-Habibi, Tahereh Barati, Saeid Amanpour
Alzheimer's disease (AD) is a mental impairment and neural degeneration which causes progressive loss of memory and cognitive functions. This age‑dependent illness is associated with extracellular amyloid plaques accumulation and twisted neurofibrillary tangles. Amyloid plaques are experimentally generated in animal models in order to investigate the disease process. In this study, we followed a rat model of AD for over a year. Wistar rats were divided randomly into two groups as control group (surgery without injection Aβ), and experimental group (two‑sided intrahippocampal amyloid‑beta injection into hippocampus)...
2018: Acta Neurobiologiae Experimentalis
https://www.readbyqxmd.com/read/29694340/possible-role-of-hippocampal-gpr55-in-spatial-learning-and-memory-in-rats
#3
Bruno A Marichal-Cancino, Alfonso Fajardo-Valdez, Alejandra E Ruiz-Contreras, Mónica Méndez-Díaz, Oscar Prospéro-García
Endocannabinoids (eCBs) are involved in the hippocampal mechanisms of spatial learning and memory in rats. Although eCBs exert many of their actions on spatial learning and memory via CB1 receptors, the putative cannabinoid receptor GPR55 (expressed in the hippocampus, cortex, forebrain, cerebellum and striatum) seems to be also involved. To investigate the potential role of GPR55 in spatial learning and memory, Wistar rats received bilateral infusions of lysophosphatidylinositol (LPI, GPR55‑agonist) into the hippocampus 5‑minutes before training‑phase in the Barnes‑maze (BM)...
2018: Acta Neurobiologiae Experimentalis
https://www.readbyqxmd.com/read/29694339/mecp2-in-central-nervous-system-glial-cells-current-updates
#4
Kedarlal Sharma, Juhi Singh, Emma E Frost, Prakash P Pillai
avMethyl‑CpG binding protein 2 (MeCP2) is an epigenetic regulator, which preferentially binds to methylated CpG dinucleotides in DNA. MeCP2 mutations have been linked to Rett syndrome, a neurodevelopmental disorder characterized by severe intellectual disability in females. Earlier studies indicated that loss of MeCP2 function in neuronal cells was the sole cause of Rett syndrome. Subsequent studies have linked MeCP2 expression in CNS glial cells to Rett syndrome pathogenesis. In this review, we have discussed the role of MeCP2 in glial subtypes, astrocytes, oligodendrocytes and microglia, and how loss of MeCP2 function in these cells has a profound influence on both glial and neuronal function...
2018: Acta Neurobiologiae Experimentalis
https://www.readbyqxmd.com/read/29694338/cerebral-hypoperfusion-in-autism-spectrum-disorder
#5
Geir Bjørklund, Janet K Kern, Mauricio A Urbina, Khaled Saad, Amira A El-Houfey, David A Geier, Salvatore Chirumbolo, Mark R Geier, Jyutika A Mehta, Jan Aaseth
Cerebral hypoperfusion, or insufficient blood flow in the brain, occurs in many areas of the brain in patients diagnosed with autism spectrum disorder (ASD). Hypoperfusion was demonstrated in the brains of individuals with ASD when compared to normal healthy control brains either using positron emission tomography (PET) or single‑photon emission computed tomography (SPECT). The affected areas include, but are not limited to the: prefrontal, frontal, temporal, occipital, and parietal cortices; thalami; basal ganglia; cingulate cortex; caudate nucleus; the limbic system including the hippocampal area; putamen; substantia nigra; cerebellum; and associative cortices...
2018: Acta Neurobiologiae Experimentalis
https://www.readbyqxmd.com/read/29694337/experimental-cerebral-hemispherectomy-in-rodent-models-a-systematic-review-of-current-literature
#6
Cezar Octavian Morosanu, Razvan Lucian Jurca, Larisa Simonca, Roxana Flavia Ilies, Remus Moldovan, Ioan Stefan Florian, Gabriela Adriana Filip
Cerebral hemispherectomy is a neurosurgical procedure that involves surgically removing one hemisphere of the brain, used as a therapeutic option in severe cases of intractable epilepsy. Several animal models have contributed to our understanding of the underlying neuromechanisms. The review was based on a PubMed search using the terms "hemispherectomy" and "mouse" or "rat" or "rodent", with no limitation of year of study or language. We identified a series of elements that were collected and analyzed that add up to our contemporary knowledge of this procedure...
2018: Acta Neurobiologiae Experimentalis
https://www.readbyqxmd.com/read/29694336/a-role-for-the-gdap1-gene-in-the-molecular-pathogenesis-of-charcot%C3%A2-marie%C3%A2-tooth-disease
#7
Weronika Rzepnikowska, Andrzej Kochański
In 2002 a series of mutations in the GDAP1 gene were reported in patients suffering from Charcot‑Marie‑Tooth disease manifesting as early-onset, progressive distal‑muscle wasting and weakness. The molecular etiology of Charcot‑Marie‑Tooth ‑GDAP1 disease has been elucidated but its pathogenesis remains unclear, especially given the seemingly contradictory function of the GDAP1 protein. Expression of GDAP1 is observed almost exclusively in neuronal cells, however, the GDAP1 protein is present in mitochondria, where it plays a role in fission, a ubiquitous process occurring in all cells...
2018: Acta Neurobiologiae Experimentalis
https://www.readbyqxmd.com/read/29369302/antimuscarinic-induced-convulsions-in-fasted-mice-after-food-intake-no-evidence-of-spontaneous-seizures-behavioral-changes-or-neuronal-damage
#8
Nurhan Enginar, Asiye Nurten, Aslı Zengin Türkmen, Gül İpek Gündoğan, Zeynep Güneş Özünal
Prolonged or repeated seizures have been shown to cause spontaneous recurrent seizures, increased anxiety‑related behavior, locomotor hyperactivity, impaired functions of learning and memory, and neuronal damage in the hippocampus and other brain regions in animals. Mice and rats treated with antimuscarinic drugs after fasting for two days or less develop convulsions after being allowed to eat ad libitum. To address whether such behavioral and neuroanatomic changes occur following these convulsions, mice treated i...
2017: Acta Neurobiologiae Experimentalis
https://www.readbyqxmd.com/read/29369301/effects-of-ascorbic-acid-on-anxiety-state-and-affect-in-a-non-clinical-sample
#9
Bettina Moritz, Marcelo Liborio Schwarzbold, Ricardo Guarnieri, Alexandre Paim Diaz, Ana Lúcia S Rodrigues, Alcir Luiz Dafre
Objective Given that the literature data indicates that ascorbic acid may have an anxiolytic effect, we hypothesized that a single oral administration of ascorbic acid could acutely affect emotional states. Methods The effects of acid ascorbic supplementation on anxiety and other emotional states were evaluated by the State‑Trait Anxiety Inventory (STAI), and Visual Analogue Mood Scale (VAMS). Immediately before, and 2 hours after receiving a single ascorbic acid dose (1000 mg) or placebo, 142 graduate students were evaluated by the STAI and VAMS in a randomized, double‑blind, placebo‑controlled trial...
2017: Acta Neurobiologiae Experimentalis
https://www.readbyqxmd.com/read/29369300/interaction-between-the-serotoninergic-and-gabaergic-systems-in-frog-retina-as-revealed-by-electroretinogram
#10
Elka Popova, Petia Kupenova
Functional interactions between serotoninergic and GABAergic systems in the vertebrate retina are largely unknown. In this study, the effects of isolated or combined stimulation of the serotonin receptors (with 100 μM serotonin) and ionotropic GABAA and GABAC receptors (with 5 mM TACA) on the electroretinographic (ERG) ON (b‑wave) and OFF (d‑wave) responses were investigated in frog eyecup preparations. It was found that serotonin alone produced a significant enhancement of the b‑ and d‑wave amplitude, while TACA alone caused its marked diminution...
2017: Acta Neurobiologiae Experimentalis
https://www.readbyqxmd.com/read/29369299/axonal-outgrowth-stimulation-after-alginate-mesenchymal-stem-cell-therapy-in-injured-rat-spinal-cord
#11
Juraj Blaško, Eva Szekiova, Lucia Slovinska, Jozef Kafka, Dasa Cizkova
Despite strong efforts in the field, spinal cord trauma still belongs among the untreatable neurological conditions at present. Given the complexity of the nervous system, an effective therapy leading to complete recovery has still not been found. One of the potential tools for supporting tissue regeneration may be found in mesenchymal stem cells, which possess anti‑inflammatory and trophic factor‑producing properties. In the context of transplantations, application of degradable biomaterials which could form a supportive environment and scaffold to bridge the lesion area represents another attractive strategy...
2017: Acta Neurobiologiae Experimentalis
https://www.readbyqxmd.com/read/29369298/effects-of-different-delayed-exercise-regimens-on-cognitive-performance-in-fimbria%C3%A2-fornix-transected-rats
#12
Elise Wogensen, Linda Marschner, Marie Gajhede Gram, Siri Mehlsen, Valdemar H B Uhre, Pernille Bülow, Jesper Mogensen, Hana Malá
Studies have shown that exercise can positively influence cognitive performance after brain injury. This study investigated the effects of different exercise regimens on allocentric place learning after fimbria‑fornix (FF) transection. One hundred and sixteen pre‑shaped rats were subjected either to a mechanical transection of the FF or control sham surgery and divided into following groups: i) no exercise (NE), ii) voluntary exercise in a running wheel (RW), iii) forced swimming exercise administered as interval training of short (3x5 min) duration (FS‑SI), iv) forced swimming exercise administered as interval training of long (3x15 min) duration (FS‑LI), v) forced swimming exercise administered as one session of short (5 min) duration (FS‑SS), and vi) forced swimming exercise administered as one session of long (15 min) duration (FS‑LS)...
2017: Acta Neurobiologiae Experimentalis
https://www.readbyqxmd.com/read/29369297/antiallodynic-effect-of-intrathecal-resiniferatoxin-on-neuropathic-pain-model-of-chronic-constriction-injury
#13
Julia Risso Parisi, Ana Laura Martins de Andrade, Josie Resende Torres Silva, Marcelo Lourenço Silva
INTRODUCTION: Injuries and/or dysfunctions in the somatosensory system can lead to neuropathic pain. Transient receptor potential vanilloid sub‑type 1 (TRPV1) play an important role in the development of allodynia and hyperalgesia following injury and the ensuing inflammatory conditions. Resiniferatoxin (RTX) is an ultrapotent synthetic TRPV1 agonist and many different administration routes are available for different mechanisms and different effects. RTX is used intraperitonially as a model of neuropathic pain or epidurally and topically to produce prolonged analgesic effects...
2017: Acta Neurobiologiae Experimentalis
https://www.readbyqxmd.com/read/29369296/top-down-and-bottom-up-competition-in-visual-stimuli-processing
#14
Tomasz S Ligeza, Agnieszka D Tymorek, Mirosław Wyczesany
Limited attention capacity results that not all the stimuli present in the visual field are equally processed. While processing of salient stimuli is automatically boosted by bottom‑up attention, processing of task‑relevant stimuli can be boosted volitionally by top‑down attention. Usually, both top‑down and bottom‑up influences are present simultaneously, which creates a competition between these two types of attention. We examined this competition using both behavioral and electrophysiological measures...
2017: Acta Neurobiologiae Experimentalis
https://www.readbyqxmd.com/read/29369295/omitted-stimulus-potential-depends-on-the-sensory-modality
#15
Oscar Hernando Hernández, Karla María Hernández-Sánchez
Determining the characteristics of Omitted Stimulus Potential (OSP) parameters using different sensory modalities is important because they reflect timing processes and have a substantial influence on time perception. At the same time, the central mechanisms of time perception associated with sensory processing can modulate cortical brain waves related to cognition. This experiment tested the relationship between parameters of the whole OSP brain wave when trains of auditory, visual or somatosensory stimuli were applied...
2017: Acta Neurobiologiae Experimentalis
https://www.readbyqxmd.com/read/29369294/developmental-neurotoxicants-and-the-vulnerable-male-brain-a-systematic-review-of-suspected-neurotoxicants-that-disproportionally-affect-males
#16
Janet K Kern, David A Geier, Kristin G Homme, Paul G King, Geir Bjørklund, Salvatore Chirumbolo, Mark R Geier
The prevalence of neurodevelopmental disorders (NDs), including autism spectrum disorder, attention‑deficit/hyperactivity disorder, tic disorder, obsessive‑compulsive disorder, and emotional disturbances, has increased notably in the past few decades. To date, debate continues as to the origins of NDs. Increases in widespread exposure to and bioaccumulation of chemical neurotoxicants have paralleled the upsurge in NDs, and are suggested to be causal agents for NDs. One consistent aspect of NDs is the male preponderance...
2017: Acta Neurobiologiae Experimentalis
https://www.readbyqxmd.com/read/29182617/in-vivo-stimulation-of-locus-coeruleus-effects-on-amygdala-subnuclei
#17
Elisa Rodríguez-Ortega, Fernando Cañadas, Francisca Carvajal, Diana Cardona
The locus coeruleus (LC) is the major noradrenergic nucleus and sends projections to almost all brain areas. A marked increase in norepinephrine release has been demonstrated in several brain areas in response to exposure to acute stressful stimuli, especially those innervated by LC projections. One of the brain areas innervated by LC neurons is the amygdala, a structure highly involved in emotional processes and memory formation. The aim of this study was to increase knowledge of the functional connectivity between the LC and the amygdala subnuclei...
2017: Acta Neurobiologiae Experimentalis
https://www.readbyqxmd.com/read/29182616/marble-burying-as-compulsive-behaviors-in-male-and-female-mice
#18
George T Taylor, Sandra Lerch, Sabine Chourbaji
Marble burying is considered an, albeit controversial, animal model of the compulsive like behaviors of obsessive-compulsive disorder (OCD). Hallmark features of OCD patients are similarities and, more prominent, differences from anxiety disorders, e.g., the absence of sex differences and resistance to spontaneous remission. We report an experiment on marble burying by male and female C57/BL6/N mice. Animals were administered either the classic anxiolytic drug, diazepam, that targets the GABA receptor or a "pure" inhibitor of the serotonin transporter, escitalopram, that has been reported to be particularly effective in OCD...
2017: Acta Neurobiologiae Experimentalis
https://www.readbyqxmd.com/read/29182615/effects-of-individual-stressors-used-in-a-battery-of-chronic-unpredictable-stress-on-long-term-plasticity-in-the-hippocampus-of-juvenile-rats
#19
Alexandra A Gorbunova, Irina V Kudryashova, Anna O Manolova, Margarita R Novikova, Mikhail Yu Stepanichev, Natalia V Gulyaeva
We have studied alterations in the properties of long-term potentiation (LTP) in hippocampal slices of juvenile rats induced by the exposure of animals to different individual stressors usually used in batteries of chronic unpredictable stress (CUS), a widely used model of depression. Social isolation for 16 h did substantially affect neither the magnitude and nor the development of LTP. The effects of stroboscopic illumination and water deprivation appeared most severe, though opposite: the first stressor had activating effect, whereas the second one inhibited the development of LTP...
2017: Acta Neurobiologiae Experimentalis
https://www.readbyqxmd.com/read/29182614/tiapride-prevents-the-aversive-but-not-the-rewarding-effect-induced-by-parabrachial-electrical-stimulation-in-a-place-preference-task
#20
María M Hurtado, Raquel García, Amadeo Puerto
The parabrachial complex has been related to the processing of both rewarding and aversive signals. This pontine area is activated after the gastrointestinal administration of rewarding nutrients, in taste aversion learning, and in response to the reinforcing and aversive effects of some drugs of abuse. Electrical stimulation of this region can induce, in different animals, preference or aversion behaviors towards a place in a rectangular three-chamber maze task. This study examined the effect of tiapride, a D2/D3 receptor antagonist, on the aversive or rewarding effects induced by electrical stimulation of the external lateral parabrachial subnucleus (NLPBe)...
2017: Acta Neurobiologiae Experimentalis
journal
journal
25185
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"