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Journal of Neurosurgical Sciences

Francesco Acerbi, Francesco Restelli, Camilla De Laurentis, Jacopo Falco, Claudio Cavallo, Morgan Broggi, Julius Höhne, Karl-Michael Schebesch, Marco Schiariti, Paolo Ferroli
BACKGROUND: In recent years several techniques have been proposed with the aim of improving tumors visualization and extent of resection and, among them, the use of photosensitive dyes is gaining great interest. Regarding the application of the two most used dyes, 5-aminolevulinic acid (5-ALA) and sodium fluorescein (SF), there is still a lack of shared and established protocols among different centers. The main objective of the present study was to evaluate the current practice of fluorescence-guided techniques in neuro-oncological surgery in Europe...
July 17, 2018: Journal of Neurosurgical Sciences
Wolfgang Senker, Harald Stefanits, Matthias Gmeiner, Wolfgang Trutschnig, Christian Radl, Andreas Gruber
BACKGROUND: The impact of diabetes on spinal surgery has been studied extensively, but very few studies have focused on minimal access spinal technologies (MAST) and complication rates in patients suffering from Type 2 Diabetes (T2DM). Diabetes increases the risk of wound healing disorders, complication rate and length of stay in the hospital. We focused on the peri- and postoperative complications of MAST in an unselected consecutive population of 187 patients suffering from degenerative disorders lumbar spine disorders...
July 17, 2018: Journal of Neurosurgical Sciences
Tamara Maghathe, William K Miller, Luke Mugge, Tarek R Mansour, Jason Schroeder
INTRODUCTION: Pituitary adenomas (PAs) are primary central nervous system (CNS) tumors, accounting for as much as 25% of intracranial neoplasms. Although existing remedies show success in treating most PAs, treatment of invasive and non-functioning PAs, in addition to functioning PAs unresponsive to standard therapy, remains challenging. With the continually increasing understanding of biochemical pathways involved in tumorigenesis, immunotherapy stands as a promising alternative therapy for pituitary tumors that are resistant to standard therapy...
July 17, 2018: Journal of Neurosurgical Sciences
Rathin Pujari, Peter J Hutchinson, Angelos G Kolias
Traumatic brain injury (TBI) remains a leading cause of mortality and disability worldwide. Surgical intervention is one of the main pillars of TBI management. The mainstay of treatment for substantial intracranial haematomas is surgical evacuation. In addition, patients with TBI may have brain swelling and increased intracranial pressure (ICP). If the latter is refractory to medical management, surgical interventions can be helpful. In this review we seek to outline the major tenets of the surgical management of TBI...
June 27, 2018: Journal of Neurosurgical Sciences
Pietro Fiaschi, Bernarda Cagetti, Filippo Badaloni, Riccardo Padolecchia, Marco Pavanello, Valtero Valsania
No abstract text is available yet for this article.
June 27, 2018: Journal of Neurosurgical Sciences
Domenico Chirchiglia, Pasquale Chirchiglia, Domenico Murrone, Francesco Signorelli
No abstract text is available yet for this article.
June 14, 2018: Journal of Neurosurgical Sciences
Igor Paredes, Irene Panero, Santiago Cepeda, Ana M Castaño-Leon, Luis Jimenez-Roldan, Ángel Perez-Nuñez, Jose A Alén, Alfonso Lagares
BACKGORUND: This study aimed to compare the accuracy of screw placement between open pedicle screw fixation and percutaneous pedicle screw fixation (MIS) for the treatment of thoracolumbar spine fractures (TSF). MATERIALS AND METHODS: Forty-nine patients with acute TSF who were treated with transpedicular screw fixation from January 2013 to December 2016 were retrospectively reviewed. The patients were divided into Open and MIS groups. Laminectomy was performed in either group if needed...
June 14, 2018: Journal of Neurosurgical Sciences
Abdullah M Abunimer, Hussam Abou-Al-Shaar, Claudio Cavallo, Mark A Mahan, Mohamed A Labib
Adult-onset intraventricular hemorrhage is a potentially life-threatening condition associated with a high morbidity and mortality rates. Intraventricular hemorrhage remains one of the most challenging entities for neurosurgeons to treat. Various medical and surgical modalities have been employed for the management of this entity with variable success and complications rates. In this paper, we review the neurosurgical interventions for the management of intraventricular hemorrhage and describe new approaches and potential therapeutic modalities for the management of this devastating condition...
May 28, 2018: Journal of Neurosurgical Sciences
Stephen Honeybul
There is now no little doubt that decompressive craniectomy can reduce mortality following severe traumatic brain injury. However the concern has always been that the reduction in mortality comes at the cost of an increase in the number of survivors with severe neurological disability. It was these concerns that prompted investigators to conduct a number of large multicentre randomised trials investigating surgical efficacy of the procedure. Whilst the results of these trials have confirmed the survival benefit that can be achieved this has only been achieved by increasing the number of survivors with severe disability and dependency...
May 28, 2018: Journal of Neurosurgical Sciences
Kyle Vankoevering, Daniel M Prevedello, Ricardu L Carrau
Malignancies of the skull base represent a highly diverse and challenging set of pathologies which exhibit a wide array of oncologic behavior. In recent decades, a number of important advances in treatment technique have evolved to improve oncologic outcomes and reduce morbidity in the treatment of these aggressive cancers. Intensity modulated radiation therapy (IMRT) has become the gold standard in radiotherapy owing to its precision planning and reduced morbidity. However heavy ion particle radiation (proton therapy, carbon ion, etc...
May 28, 2018: Journal of Neurosurgical Sciences
Christopher A Hilditch, Waleed Brinjikji, Anderson C Tsang, Patrick Nicholson, Alex Kostynskyy, Michael Tymianski, Timo Krings, Ivan Radovanovic, Vitor M Pereira
BACKGROUND AND PURPOSE: We calculated the PHASES and ELAPSS scores for a large cohort of ruptured intracranial aneurysms (RIA) in order to determine whether these RIA would have been pre-emptively treated or closely followed-up should they have been detected prior to rupture. MATERIALS AND METHODS: We retrospectively reviewed a consecutive series of RIA over a 20 year period. The primary outcome of this study was the PHASES score of each ruptured aneurysm included...
May 28, 2018: Journal of Neurosurgical Sciences
Alexandre B Todeschini, Bradley A Otto, Ricardo L Carrau, Daniel M Prevedello
BACKGROUND: Meningiomas are the most common primary intracranial tumor, arising from different locations, including the skull base. Despite advances in adjuvant treatments, surgical resection remains the main and best treatment for meningiomas. New surgical strategies, such as the endoscopic endonasal approach, have greatly contributed in achieving maximum and total safe resection, preserving the patient's neurological function. METHODS: Based on the senior authors large experience and a review of the current literature, we have compiled this chapter...
May 28, 2018: Journal of Neurosurgical Sciences
Andrea Cardia, Irene Zerbetto, Delia Cannizzaro, Piero Picozzi, Maurizio Fornari, Paolo Levi Setti, Franco Servadei
No abstract text is available yet for this article.
May 28, 2018: Journal of Neurosurgical Sciences
Edvin Zekaj, Andrea Franzini, Alberto R Bona, Domenico Servello
No abstract text is available yet for this article.
May 28, 2018: Journal of Neurosurgical Sciences
Leonello Tacconi, Roberto Spinelli
BACKGROUND: The common treatment for lumbar canal stenosis involves an open surgical decompression with laminectomy and foraminotomy, even if spinal surgery is moving towards minimal invasiveness procedures. Minimal Invasive Surgery initially and recently spinal endoscopic techniques are becoming the standard procedures for lumbar disk prolapsed in consideration of the less surgical invasiveness with a considerable reducing in the amount of normal anatomy violation, in less risk of iatrogenic post-operative instability, minimal scar tissue formation and negligible blood loss when compared to the standard open approach...
May 28, 2018: Journal of Neurosurgical Sciences
Cesare Zoia, Daniele Bongetta, Francesco Guerrini, Cristiano Alicino, Andrea Cattalani, Simonetta Bianchini, Renato J Galzio, Sabino Luzzi
BACKGROUND: Higher life expectancy and higher mean age in general population created growing interest in medical and surgical management of meningiomas in elderly. It is well known that, due to possible complications, pre-operative status and comorbidities, expecially in aged people, should be carefully considerated in the decision-making process. We described our experience with this kind of patients and analized the influence of complications on the outcome. METHODS: We conducted a monocentric retrospective study to evaluate outcome and complications in elderly patients that underwent intracranial meningioma surgery in our center in a ten year period...
May 28, 2018: Journal of Neurosurgical Sciences
Ruth A O'leary, Alistair D Nichol
Traumatic brain injury is a leading cause of morbidity and mortality globally, particularly among young people, with significant social and economic effects. The World Health Organization (WHO) estimates that more than five million people die each year from traumatic injuries worldwide. While public health initiative such as seatbelts and airbags have had a major impact, it will be impossible to prevent traumatic brain injury, it is therefore that we understand the pathophysiology of secondary brain injury to be able to effectively treat our patient but aloes to develop novel targets of future interventions...
May 22, 2018: Journal of Neurosurgical Sciences
Arjun V Pendharkar, Maryam N Shahin, Claudio Cavallo, Xiaochun Zhao, Allen L Ho, Eric S Sussman, Gerald A Grant
Craniosynostosis (CS) is defined as the premature fusion of one or more calvarial sutures. This carries several consequences, including abnormal/asymmetric cranial vault development, increased intracranial pressure, compromised neurocognitive development, and craniofacial deformity. Definitive management is surgical with the goal of protecting cerebral development by re-establishing normal cranial vault expansion and correcting cosmetic deformity. In today's practice, CS surgery has advanced radically from simple craniectomies to major cranial vault reconstructive (CVR) procedures...
May 22, 2018: Journal of Neurosurgical Sciences
Claudio Cavallo, Camilla De Laurentis, Ignazio G Vetrano, Jacopo Falco, Morgan Broggi, Marco Schiariti, Paolo Ferroli, Francesco Acerbi
INTRODUCTION: Sodium Fluorescein (SF) is a green, water-soluble dye with the capacity to accumulate in cerebral areas as a result of damaged blood-brain barrier (BBB); this property allows SF to concentrate specifically at the tumor site of various types of brain neoplasms, making the tumor tissue more clearly visible. EVIDENCE ACQUISITION: A literature search (1947-2018) was conducted with the keywords "fluorescein neurosurgery", "YELLOW neurosurgery", "fluorescein brain tumor", "YELLOW brain tumor"...
May 22, 2018: Journal of Neurosurgical Sciences
Masoom Desai, Abhi Jain
PURPOSE: Traumatic brain injury has a high incidence worldwide and is associated with significant morbidity and mortality. Moreover, TBI has enduring implications in several domains and limits overall quality of life even in the survivors. Neuroprotective strategies are needed to limit morbidity and mortality associated with this disease process. Insight into the failure of these strategies is required to pursue future research successfully. BACKGROUND: Several different approaches involving pharmacological, surgical and usage of certain devices have been attempted in traumatic brain injury...
May 22, 2018: Journal of Neurosurgical Sciences
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