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Journal of Neurosurgical Sciences

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https://www.readbyqxmd.com/read/28407709/synergistic-antitumor-effect-of-ing4-pten-double-tumor-suppressors-mediated-by-adenovirus-modified-with-rgd-on-glioma
#1
Yaodong Zhao, Jiarong Wang, Jicheng Yang, Jingcheng Miao
BACKGROUND: Gene therapy is regarded as a new and promising therapeutic modality for cancers, and adenovirus is one of the most frequently used vectors. However, because of low or absent coxsackievirus and adenovirus receptor levels on the surface of many kinds of tumor cells, the efficiency of adenovirus infection of target tumor cells may be low. Meanwhile, gene therapy by a single vector carrying two or more anti-oncogenes can improve treatment effects and reduce side effects from vectors...
April 12, 2017: Journal of Neurosurgical Sciences
https://www.readbyqxmd.com/read/28378955/high-altitude-exposure-as-possible-predisposing-factor-for-pituitary-adenoma-apoplexy-histologically-confirmed-case-report
#2
Matteo Vitali, Frank R Canevari, Andrea Cattalani, Vincenzo Grasso, Teresa Somma, Luigi M Cavallo, Andrea Barbanera
No abstract text is available yet for this article.
April 4, 2017: Journal of Neurosurgical Sciences
https://www.readbyqxmd.com/read/28322536/recent-perspectives-of-metabolic-alterations-in-neurological-disorders
#3
Ai-Ling Ji, Xia Zhang, Wei-Wei Chen, Wen-Juan Huang
No abstract text is available yet for this article.
March 21, 2017: Journal of Neurosurgical Sciences
https://www.readbyqxmd.com/read/28322535/neuropsychological-rehabilitation-and-psychotherapy-of-adult-traumatic-brain-injury-patients-with-depression-a-systematic-review-and-meta-analysis
#4
Zeng-Qiang Liu, Xue Zeng, Chen-Yang Duan
INTRODUCTION: There is still insufficient appreciation whether neuropsychological rehabilitation and psychotherapy are effective in attenuating depression following traumatic brain injury (TBI). This knowledge gap was addressed in the present systematic review and meta- analysis of the literature. EVIDENCE ACQUISITION: We conducted electronic database (Medline, PsychINFO, Scopus) searches (time frame: January 1, 2005 - December 31, 2015) for clinical studies that had tested neuropsychological rehabilitation and psychotherapy in adult TBI survivors with depression...
March 21, 2017: Journal of Neurosurgical Sciences
https://www.readbyqxmd.com/read/28263047/mapping-the-connectome-in-awake-surgery-for-gliomas-an-update
#5
Hugues Duffau
The traditional principle underlying oncological neurosurgery is to remove a tumor mass displacing the brain in order to increase survival. Recently, advances in connectomics enabled an improved understanding of cerebral processing, and led to a paradigmatic shift in tumor surgery based upon interactions between neurooncology and cognitive neurosciences. First, glioma is not a focal tumor invaginated within the parenchyma but a diffuse neoplastic disease migrating in the brain. This concept resulted in a new surgical ideology, i...
March 6, 2017: Journal of Neurosurgical Sciences
https://www.readbyqxmd.com/read/28252264/vasopressor-support-in-managing-acute-spinal-cord-injury-a-knowledge-update
#6
John K Yue, Rachel Tsolinas, John F Burke, Hansen Deng, Pavan S Upadhyayula, Caitlin K Robinson, Young M Lee, Andrew K Chan, Ethan A Winkler, Sanjay S Dhall
INTRODUCTION: Managing neurogenic shock following acute traumatic spinal cord injury (SCI) is challenging. Current guidelines target mean arterial pressure (MAP) above 85-90 mmHg to maintain cord perfusion and reduce ischemia/secondary injury. While early vasopressor utilization has been associated with improved outcomes, recent updates regarding indications of specific vasopressors for refinement of existing guidelines are needed. EVIDENCE ACQUISITION: A comprehensive search was conducted using the National Library of Medicine PubMed database between 01/2010 and 01/2017 targeting vasopressor use in the setting of neurogenic/spinal shock and/or hypotension following acute SCI in adult patients...
March 1, 2017: Journal of Neurosurgical Sciences
https://www.readbyqxmd.com/read/28240529/decreased-vessel-wall-enhancement-as-a-biomarker-for-response-to-corticosteroids-in-a-patient-with-cns-vasculitis
#7
Waleed Brinjikji, Vance Lehman, John Huston, Patrick H Luetmer, Giuseppe Lanzino, Alejandro A Rabinstein
No abstract text is available yet for this article.
February 27, 2017: Journal of Neurosurgical Sciences
https://www.readbyqxmd.com/read/28206726/are-modic-type-2-disc-changes-associated-with-low-grade-infections-a-pilot-study
#8
Lorenzo Drago, Carlo L Romanò, Riccardo Cecchinato, Jorge H Villafañe, Elena De Vecchi, Claudio Lamartina, Pedro Berjano
BACKGROUND: The aim of this study is to compare intra-operative cultural examination in patients undergoing elective surgery for low-back pain with Modic 2 changes to patients without Modic signs. The aim of this study is to compare intra-operative cultural examination in patients undergoing elective surgery for low-back pain with Modic 2 changes to patients without Modic signs. METHODS: Sixteen patients with Modic 2 changes were compared with 23 patients without Modic signs...
February 15, 2017: Journal of Neurosurgical Sciences
https://www.readbyqxmd.com/read/28181779/elevated-brain-derived-neurotrophic-factor-bdnf-levels-in-plasma-but-not-serum-reflect-in-vivo-functional-viability-of-infused-mesenchymal-stem-cells-after-middle-cerebral-artery-occlusion-in-rat
#9
Hideyuki Nakamura, Yuichi Sasaki, Masanori Sasaki, Yuko Kataoka-Sasaki, Shinichi Oka, Masahito Nakazaki, Takahiro Namioka, Ai Namioka, Rie Onodera, Junpei Suzuki, Hiroshi Nagahama, Takeshi Mikami, Masahiko Wanibuchi, Jeffery D Kocsis, Osamu Honmou
BACKGROUND: Intravenous infusion of mesenchymal stem cells (MSCs) derived from adult bone marrow elicits functional recovery in rat stroke models and clinical studies in patients are ongoing. Brain derived neurotrophic factor (BDNF) is a neurotrophic factor produced by MSCs and may contribute to their therapeutic efficacy. The purpose of the current study was to determine if BDNF is elevated in infarcted brain and in which compartment of blood (plasma or serum) after intravenous MSC infusion in a middle cerebral artery occlusion (MCAO) model in the rat...
February 8, 2017: Journal of Neurosurgical Sciences
https://www.readbyqxmd.com/read/28181778/intracranial-subdural-empyema-diagnosis-and-treatment-update
#10
Pier P Mattogno, Giuseppe LA Rocca, Francesco Signorelli, Massimiliano Visocchi
No abstract text is available yet for this article.
February 8, 2017: Journal of Neurosurgical Sciences
https://www.readbyqxmd.com/read/28417618/indocyanine-green-videoangiography-application-in-distal-m4-middle-cerebral-artery-aneurysm-surgery
#11
Oriela Rustemi, Renato Scienza, Alessandro Della Puppa
No abstract text is available yet for this article.
June 2017: Journal of Neurosurgical Sciences
https://www.readbyqxmd.com/read/28417617/indocyanine-green-videoangiography-the-thin-border-between-a-useful-tool-and-an-illusion-of-safety
#12
Giacomo Pavesi, Andrea Prontera, Alberto Feletti
No abstract text is available yet for this article.
June 2017: Journal of Neurosurgical Sciences
https://www.readbyqxmd.com/read/28417616/cervical-radiculopathy-caused-by-vertebral-artery-loop
#13
Vittorio M Russo, Arthur J Ulm, Nigel Kellow, Adrian T Casey
No abstract text is available yet for this article.
June 2017: Journal of Neurosurgical Sciences
https://www.readbyqxmd.com/read/28417615/granular-cell-tumor-of-the-orbit-pathological-features-and-treatment
#14
Simone Ulivieri, Giovanni Muscas, Laura Lavalle, Antonio Giorgio, Damiana Tacchini, Roberto Lio, Giuseppe Oliveri, Mario Fruschelli
No abstract text is available yet for this article.
June 2017: Journal of Neurosurgical Sciences
https://www.readbyqxmd.com/read/28417614/spinal-epidural-abscess-caused-by-brucella-species-a-review-of-17-cases
#15
Qin Zhang, Xiaohui Yang, Honglin Yu, Benrang Jia, Bin Meng
BACKGROUND: Spinal epidural abscess (SEA) is a rarely encountered clinical entity during the course of Brucella infection. METHODS: We reported 17 patients diagnosed with Brucellar SEA for a mean follow-up of 15 months. Spinal epidural abscess was detected by magnetic resonance imaging in all cases. Brucella diagnosis was established by serological tests. Patients were administered antibiotics for duration of 6 to 16 weeks. RESULTS: SEA was localized in lumbar region in 9 patients, thoracic in 4 patients, cervical in 3 patients, both thoracic and lumbar in 1 patient...
June 2017: Journal of Neurosurgical Sciences
https://www.readbyqxmd.com/read/27882906/vertebral-fracture-due-to-a-solitary-bone-cyst
#16
REVIEW
Ali Genç, Suheyla U Bozkurt, Serdar Ozgen, Mustafa N Pamir
No abstract text is available yet for this article.
April 2017: Journal of Neurosurgical Sciences
https://www.readbyqxmd.com/read/27882905/a-familial-incidence-of-l1-l2-disc-herniation
#17
LETTER
Abtin Shahlaee, Vafa Rahimi-Movaghar
No abstract text is available yet for this article.
April 2017: Journal of Neurosurgical Sciences
https://www.readbyqxmd.com/read/27882904/neuroendoscopic-diagnosis-and-clinical-management-of-cryptococcal-choroid-plexitis-in-an-immunocompetent-pregnant-woman
#18
LETTER
Giuseppe Talamonti, Alberto Volonterio, Marco Picano, Adnan Al Mashni, Moreno Bolzon, Giuseppe D'Aliberti
No abstract text is available yet for this article.
April 2017: Journal of Neurosurgical Sciences
https://www.readbyqxmd.com/read/27882903/results-of-hemihypoglossal-facial-nerve-anastomosis-in-the-treatment-of-facial-nerve-paralysis-after-failed-stereotactic-radiosurgery-for-vestibular-schwannoma
#19
Tomasz A Dziedzic, Przemysław Kunert, Andrzej Marchel
Vestibular schwannoma treatment with stereotactic radiosurgery (SRS) carries a risk of facial nerve (CNVII) palsy that is lower than that with microneurosurgery. The results of hemihypoglossal-facial nerve anastomosis (HHFA) have not been described yet in CNVII palsy after failed stereotactic radiosurgery (SRS). Here we report a case series of the first four consecutive patients (three women; average age 58.5, age range: 46-74), who underwent HHFA due to failed SRS. All patients were admitted because of progressive peripheral facial nerve palsy...
April 2017: Journal of Neurosurgical Sciences
https://www.readbyqxmd.com/read/27406955/biobridge-concept-in-stem-cell-therapy-for-ischemic-stroke
#20
REVIEW
Michael G Liska, Marci G Crowley, Hung Nguyen, Cesar V Borlongan
Stroke causes a significant social and economic burden to the society. Despite advancement in awareness and prevention of stroke, there are still limited treatment options for stroke patients. One of the emerging experimental therapies for stroke is stem cell transplantation. The conventional belief of stem cell mechanisms is that the protective effects are produced by either cell replacement or releasing trophic factors. While the exact mechanisms of action of stem cells are not completely understood, recent evidence demonstrates another possible mechanism of stem cells...
April 2017: Journal of Neurosurgical Sciences
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