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Acta Reumatológica Portuguesa

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https://www.readbyqxmd.com/read/28605750/anticentromere-antibody-positive-ackerman-s-syndrome-with-granulomatous-anterior-uveitis
#1
Susana Rilhas Fernandes, Vera Las, Joana Borges, Cândida Silva, Augusto Faustino
Ackerman's Syndrome or Intersticial Granulomatous Dermatitis with Arthritis has been an issue of increasing number of reports in the last decade which had focused its heterogeneous cutaneous and rheumatologic expression besides the initial manifestations reported by Ackerman and his group. Granulomatosis anterior uveitis has not been previously described. Some patients are reported to have positive autoantibodies but association with anticentromere antibodies has not been previously described as well, to our knowledge...
June 12, 2017: Acta Reumatológica Portuguesa
https://www.readbyqxmd.com/read/28605749/radiculopathy-in-a-patient-with-chronic-tophaceus-gout-vertebral-imaging
#2
Joana Borges, Cláudia Miguel, Susana Fernandes, Rui Leitão, Augusto Faustino
INTRODUCTION: Spinal involvement is infrequent in chronic gout. However, some cases of back pain with radiculopathy secondary to this etiology have been reported. CASE REPORT: 56-year old male patient, with history of arterial hypertension, hypertriglyceridemia, obesity, glucose intolerance and alcohol abuse, diagnosed with gout in his fifth decade of life. The patient was started on urate lowering therapy, with poor compliance, and evolved with sustained hyperuricemia, recurrent episodes of arthritis, and growth of gouty tophi on the elbows, wrists, hands and knees...
June 2, 2017: Acta Reumatológica Portuguesa
https://www.readbyqxmd.com/read/28535545/portuguese-recommendations-for-the-use-of-methotrexate-in-rheumatic-diseases-2016-update
#3
Ana Catarina Duarte, Daniela Santos-Faria, Maria João Gonçalves, Alexandre Sepriano, Ana Filipa Mourão, Cátia Duarte, Joana Sousa Neves, Ana Filipa Águeda, Pedro Ávila Ribeiro, Alexandra Daniel, Adriano Neto, Ana Cordeiro, Ana Rodrigues, Anabela Barcelos, Cândida Silva, Cristina Ponte, Elsa Vieira-Sousa, Filipa Teixeira, Filipa Oliveira-Ramos, Filipe Araújo, Filipe Barcelos, Helena Canhão, Helena Santos, João Ramos, Joaquim Pereira, José Costa, José António Melo Gomes, Luís Cunha-Miranda, Lúcia Costa, Marcos Cerqueira, Margarida Cruz, Maria José Santos, Miguel Bernardes, Paula Oliveira, Pedro Abreu, Ricardo Figueira, Rita Barros, Sandra Falcão, Patrícia Pinto, Sofia Pimenta, Susana Capela, Vitor Teixeira, João Eurico Fonseca
BACKGROUND: Methotrexate (MTX) is the first-line drug in the treatment of rheumatoid arthritis (RA) and the most commonly prescribed disease modifying anti-rheumatic drug. Moreover, it is also used as an adjuvant drug in patients under biologic therapies, enhancing the efficacy of biologic agents. OBJECTIVES: To review the literature and update the Portuguese recommendations for the use of MTX in rheumatic diseases first published in 2009. METHODS: The first Portuguese guidelines for the use of MTX in rheumatic diseases were published in 2009 and were integrated in the multinational 3E Initiative (Evidence Expertise Exchange) project...
May 9, 2017: Acta Reumatológica Portuguesa
https://www.readbyqxmd.com/read/28482357/systemic-sclerosis-induced-by-interferon-alfa-treatment-of-melanoma
#4
Joana Leite Silva, Daniela Santos Faria, Filipa Teixeira, Maria Carmo Afonso, Daniela Peixoto
Systemic sclerosis is a connective tissue disease characterized by a complex pathogenesis and a multi organ involvement of unknown etiology. Genetic features and environmental factors, as the use of some drugs, influence the onset of the clinical picture. The authors describe a case of a patient who developed systemic sclerosis after treatment of melanoma with interferon alfa-2b, drug rarely implicated in the induction of this disease.
May 8, 2017: Acta Reumatológica Portuguesa
https://www.readbyqxmd.com/read/28535544/portuguese-recommendations-for-the-use-of-biological-therapies-in-patients-with-rheumatoid-arthritis-2016-update
#5
Catia Duarte, Joana Sousa-Neves, Ana Águeda, Pedro Ribeiro, Alexandra Daniel, Gisela Eugénio, Sofia Serra, Filipe Araújo, Anabela Barcelos, Barcelos Filipe, Miguel Bernardes, Helena Canhão, Marcos Cerqueira, Susana Capela, Ana Cordeiro, Flavio Costa, Lucia Costa, Margarida Cruz, Luis Cunha Miranda, Catarina Duarte, Sandra Falcão, Daniela Faria, Ricardo Figueira, João Pedro Freitas, Maria João Gonçalves, João Madruga Dias, José Melo Gomes, Ana Filipa Mourão, Adriano Neto, Filipa Oliveira Ramos, Sofia Pimenta, Patricia Pinto, Joaquim Polido Pereira, Cristina Ponte, João Ramos, Ana Rodrigues, Helena Santos, Maria José Santos, Alexandre Sepriano, Candida Silva, José Tavares Costa, Filipa Teixeira, Vitor Teixeira, Paula Valente, Elsa Vieira-Sousa, Rita Barros, Pedro Abreu, João Eurico Fonseca
OBJECTIVE: To update the recommendations for the treatment of Rheumatoid Arthritis (RA) with biological therapies, endorsed by the Portuguese Society of Rheumatology (SPR). METHODS: These treatment recommendations were formulated by Portuguese rheumatologists based on literature evidence and consensus opinion. At a national meeting the 10 recommendations were discussed and updated. The document resulting from this meeting circulated to all Portuguese rheumatologists, who anonymously voted online on the level of agreement with the recommendations...
May 4, 2017: Acta Reumatológica Portuguesa
https://www.readbyqxmd.com/read/28379209/diagnostic-utility-of-magnetic-ressonance-imaging-in-eosinophilic-fasciitis
#6
Alexandra Daniel, Gisela Eugénio, Sara Serra, Armando Malcata, Maria João Salvador
No abstract text is available yet for this article.
April 5, 2017: Acta Reumatológica Portuguesa
https://www.readbyqxmd.com/read/28375198/lupus-protein-losing-enteropathy-patient-with-protein-c-and-protein-s-deficiency-induced-thrombosis-a-case-report-with-review-of-the-literature
#7
Ratchaya Lertnawapan, Dussadee Sakonlaya
A case report of SLE with PLE in an Asian female; presented with edema, pleural effusion, ascites and profound hypoalbuminemia. She also had severe protein C and protein S depletion from GI loss which caused extensive thrombosis. Her disease was refractory to the treatment with high dose steroid, azathioprine, mycophenolate mofetil and cyclophosphamide. Bowel resection was performed without improvement. Fortunately, the patient responded to another course of pulse methyl prednisolone and a second line medication after surgery...
March 27, 2017: Acta Reumatológica Portuguesa
https://www.readbyqxmd.com/read/28375199/stevens-johnson-syndrome-and-toxic-epidermal-necrolysis-in-childhood-onset-systemic-lupus-erythematosus-patients-a-multicenter-study
#8
Ana Paula Sakamoto, Clovis Artur Silva, Claudia Saad-Magalhães, Aline Nicácio Alencar, Rosa Maria Rodrigues Pereira, Katia Kozu, Cassia Maria Passarelli Lupoli Barbosa, Maria Teresa Terreri
OBJECTIVE: To assess Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) in a large population of childhood-onset systemic lupus erythematosus (cSLE) patients. METHODS: Multicenter study including 852 cSLE patients followed in Pediatric Rheumatology centers in São Paulo, Brazil. SJS was defined as epidermal detachment below 10% of body surface area (BSA), overlap SJS-TEN 10-30% and TEN greater than 30% of BSA. RESULTS: SJS and TEN was observed in 5/852 (0...
March 26, 2017: Acta Reumatológica Portuguesa
https://www.readbyqxmd.com/read/28371796/interventions-aiming-to-reduce-early-retirement-due-to-rheumatic-diseases
#9
Pedro Almeida Laires, Miguel Gouveia, Helena Canhão
INTRODUCTION: Aging of the population and early retirement translates into productivity losses to society. Persistence of working life is crucial to counteract this sustainability issue faced by western countries. Musculoskeletal and rheumatic diseases (RD) may cause work disability and early exit from work, including early retirement. The objective of this article is to review the current knowledge about interventions aiming to reduce early retirement due to RD. METHODS: We searched PubMed and The Cochrane Library for studies either in English or Portuguese between January 2000 and June 2016 that evaluated the impact of interventions targeting early retirement in RD patients still at work...
March 5, 2017: Acta Reumatológica Portuguesa
https://www.readbyqxmd.com/read/28371797/real-life-effectiveness-of-golimumab-in-biologic-na%C3%A3-ve-patients-with-rheumatoid-arthritis-data-from-the-rheumatic-diseases-portuguese-register-reuma-pt
#10
Ana Filipa Mourão, Célia Ribeiro, Joana Borges, Maria João Gonçalves, Miguel Bernardes, Susana Fernandes, Raquel Dezerto, Pedro Laires, Patrícia Machado, Mónica Eusébio, Maria José Santos, Helena Canhão
OBJECTIVES: To assess the effectiveness of subcutaneous Golimumab 50 mg/monthly combined with methotrexate (SC GLM + MTX) over 52 weeks of treatment, in biologic-naïve RA patients, in a multicentre nationwide cohort from the Rheumatic Diseases Portuguese Register (Reuma.pt). METHODS: Data for this observational study was collected from March 2011 to August 2015. Disease activity (DAS28), functional capacity (HAQ) and Patient Global Disease Assessment (PGDA) were measured at baseline and weeks 12, 24 and 52 of treatment...
February 18, 2017: Acta Reumatológica Portuguesa
https://www.readbyqxmd.com/read/28375193/uva1-for-diffuse-cutaneous-systemic-sclerosis-in-a-fitzpatrick-skin-type-vi-patient-outcomes-in-the-modified-rodnan-skin-score
#11
Bárbara Roque Ferreira, Ana Rita Gameiro, Maria Manuel Brites, Hugo Schönenberger Oliveira, José Pedro Reis
INTRODUCTION: Cutaneous sclerosis can lead to important mobility impairment. Ultraviolet (UV) A1 phototherapy may improve skin sclerosis, although most of the studies have been with Caucasian patients. MATERIAL AND METHODS: A 44-year-old patient, Fitzpatrick skin type VI, was being followed up with the diagnosis of diffuse cutaneous systemic sclerosis. He had significant mobility impairment, especially of the right hand and arm. In 2015 he started UVA1 phototherapy daily, Monday until Friday (Waldmann® 7001 UVA cabin equipped with 40 Philips TL/10R lamps - spectral irradiation between 340 and 400 nm)...
January 31, 2017: Acta Reumatológica Portuguesa
https://www.readbyqxmd.com/read/28375195/risk-factors-for-late-deep-infection-after-total-hip-arthroplasty-in-patients-with-rheumatoid-arthritis
#12
Shinya Hayashi, Shingo Hashimoto, Koji Takayama, Tomoyuki Matsumoto, Ken Takebe, Yasuhiro Terashima, Ryosuke Kuroda, Yoshitada Sakai, Kazunari Ishida, Kotaro Nishida
OBJECTIVE: Postoperative infections, a serious complication of orthopedic surgery, occur 2-4 times more frequently in patients with rheumatoid arthritis (RA) without adjustment for medication. Some studies have demonstrated a similar risk of postoperative infection following orthopedic surgery regardless of whether patients underwent tumor necrosis factor-α (TNF-α) inhibitor therapy; however, other studies have reported a higher risk with TNF-α inhibitor use. However, few reports have focused on the correlation between TNF-α inhibitor use and postoperative late infection...
January 21, 2017: Acta Reumatológica Portuguesa
https://www.readbyqxmd.com/read/28371576/juvenile-systemic-lupus-erythematosus-and-acute-pancreatitis-a-rare-and-potentially-fatal-presentation
#13
Francisca Aguiar, Sandra Pereira, Mariana Rodrigues, Augusto Ribeiro, Iva Brito
No abstract text is available yet for this article.
January 2017: Acta Reumatológica Portuguesa
https://www.readbyqxmd.com/read/28371575/elastofibroma-dorsi-a-forgotten-cause-of-chest-pain
#14
Filipa Vieira, Diogo Rocha
OBJECTIVES: Elastofibroma dorsi is an uncommon benign tumor, typically located in the subscapularis region. Our goal is to describe the main features of elastofibroma dorsi to increase awareness of its existence and proper management. MATERIAL AND METHODS: We report a case of a 59-year-old woman with bilateral Elastofibroma dorsi and made a brief review of the epidemiological, clinical and radiodiagnostic features of this entity. RESULTS: Imaging features can confidently diagnose this lesion, especially MRI, in addition to physical examination, with no need for biopsy...
January 2017: Acta Reumatológica Portuguesa
https://www.readbyqxmd.com/read/28371574/tofacitinib-suppresses-disease-activity-and-febrile-attacks-in-a-patient-with-coexisting-rheumatoid-arthritis-and-familial-mediterranean-fever
#15
Kevser Gök, Gizem Cengiz, Kemal Erol, Salih Ozgocmen
Familial Mediterranean fever (FMF) is the most common hereditary auto-inflammatory (periodic fever) syndrome, and usually successfully treated with colchicine. However, nearly 5-10% of FMF cases are resistant or intolerant to colchicine and treatment options are highly restricted in these cases. Biologics including anakinra, canakinumab, rilonacept, etanercept, infliximab, interferon-alpha, and tocilizumab are shown to have efficacy to control FMF attacks. Tofacitinib, a Janus kinase (JAK) inhibitor, is an orally administered non-biologic disease modifying anti-rheumatic drug for the treatment of rheumatoid arthritis (RA)...
January 2017: Acta Reumatológica Portuguesa
https://www.readbyqxmd.com/read/28371573/pachymeningitis-and-cerebral-granuloma-in-granulomatosis-with-polyangiitis-is-rituximab-a-promising-treatment-option
#16
Carlos Costa, Tânia Santiago, Joana Espirito-Santo, João Rovisco, Jorge Silva, Armando Malcata
Granulomatosis with polyangiitis (GPA) is a rare autoimmune disease characterized by granulomatous inflammation involving upper and lower respiratory tract, kidneys and peripheral nervous system. However, central nervous system involvement is uncommon and frequently refractory to classical therapy. Rituximab has emerged as promising alternative, but published reports are scarce. We report a case of pachymeningitis and cerebral granuloma in a patient with a history of severe generalized GPA, treated with rituximab...
January 2017: Acta Reumatológica Portuguesa
https://www.readbyqxmd.com/read/28371572/portuguese-translation-cross-cultural-adaptation-and-reliability-of-the-questionnaire-%C3%A2-start-back-screening-tool%C3%A2-sbst
#17
Armando Raimundo, José Parraça, Nuno Batalha, Pablo Tomas-Carus, Jaime Branco, Jonathan Hill, Narcis Gusi
OBJECTIVE: To translate and perform the cross-cultural adaptation of the StarT Back Screening Tool (SBST) questionnaire to assessment and screening low back pain for Portuguese application, and test their reliability. METHOD: To establish conceptual equivalence in item, semantic and operational concern, there were performed two translations into Portuguese in a independently way. A combined version was obtained by consensus among the authors of the translations in order to be achieved a noticeable version in semantic terms and easy to understand...
January 2017: Acta Reumatológica Portuguesa
https://www.readbyqxmd.com/read/28371571/the-effects-of-acupuncture-versus-sham-acupuncture-in-the-treatment-of-fibromyalgia-a-randomized-controlled-clinical-trial
#18
Fatma Gülçin Uğurlu, Nebahat Sezer, Lale Aktekin, Fatma Fidan, Fatih Tok, Selami Akkuş
OBJECTIVE: The aim of this manuscript is to determine and to compare the efficacy of real acupuncture with sham acupuncture on fibromyalgia (FM) treatment. METHODS: 50 women with FM were randomized into 2 groups to receive either true acupuncture or sham acupuncture. Subjects were evaluated with VAS (at night, at rest, during activity), SF-36, Fibromyalgia Impact Questionnaire (FIQ), Beck Depression scale (BDI), Fatigue Severity Scale (FSS) at baseline, 1 month and 2 months after the 1st session...
January 2017: Acta Reumatológica Portuguesa
https://www.readbyqxmd.com/read/28371570/general-practitioners-and-rheumatologists-new-bridges-for-a-successful-cooperation
#19
José António Pereira da Silva, Rui Cernadas, José Canas da Silva
No abstract text is available yet for this article.
January 2017: Acta Reumatológica Portuguesa
https://www.readbyqxmd.com/read/28198796/carbonic-anhydrase-i-and-ii-autoantibodies-in-beh%C3%A3-et-s-disease
#20
Ahmet Mentese, Ahmet Alver, Selim Demir, Aysegul Sumer, Serap Ozer Yaman, Murat Karkucak, Arzu Aydin Capkin, Diler Us Altay, Ibrahim Turan
BACKGROUND: Behçet's disease is a vasculitis, seen more frequently around the Mediterranean and the Far East, and evinces with oral and genital ulcerations, skin lesions and uveitis. Carbonic anhydrase (CA) is a metalloenzyme which is widely distributed in the living world, and it is essential for the regulation of acid-base balance. Anti-CA antibodies have been reported in many disorders, such as systemic lupus erythematosus, Sjögren's syndrome, rheumatoid arthritis, endometriosis, idiopathic chronic pancreatitis, type 1 diabetes and Graves' disease...
January 2017: Acta Reumatológica Portuguesa
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