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Journal of Nuclear Medicine Technology

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https://www.readbyqxmd.com/read/29127252/validation-of-an-ergonomic-method-to-withdraw-99m-tc-radiopharmaceuticals
#1
Sandy Blondeel-Gomes, Solène Marie, Julien Fouque, Sabrina Loyeau, Olivier Madar, François Lokiec
The main objective of the present work was to ensure quality of radiopharmaceuticals syringes withdrawn with a "Spinal needle/obturator In-Stopper" system. Methods: Visual examinations and physicochemical tests are performed at T0 and T+4h for [(99m)Tc]albumin nanocolloid and T+7h for [(99m)Tc]eluate, [(99m)Tc] HydroxyMethylene DiPhosphonate and [(99m)Tc]Human Serum Albumin. Microbiological validation was performed according to European pharmacopoeia. Fingertip radiation exposure was evaluated to confirm the safety of the system...
November 10, 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/29127251/looking-beyond-the-indication-bone-scan-for-trauma-providing-unsuspected-initial-diagnosis-of-acute-critical-lower-limb-arterial-compromise
#2
Fathima Fijula Palot Manzil, Samuel E Almodovar, Pradeep Bhambhvani
We report a case of rare incidental initial detection of unsuspected arterial supply compromise to the right lower extremity on a bone scan done to rule out fracture in a patient with right hip pain following a fall. Follow up CT angiogram confirmed near complete occlusion of right lower extremity arteries for which patient underwent above knee amputation.
November 10, 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/29127250/malignant-peripheral-nerve-sheath-tumours-of-the-pericardium-in-a-patient-with-neurofibromatosis-type-1-the-diagnostic-value-of-18f-fdg-pet-ct-and-i-123-mibg-spect-ct
#3
Mathieu Charest, Josephine Pressacco, Jaramie Thomas-Gittens
A 25 year old female with known neurofibromatosis type 1 with a large anterior mediastinal mass was investigated. F18-FDG PET-CT revealed a radiotracer avid anterior mediastinal mass with SUVmax of 4.3 and demonstrating a hypoactive center. The Iodine-123 MIBG SPECT-CT study performed subsequently did not demonstrate any uptake, thereby excluding for the most part the diagnoses of paraganglioma or neuroblastoma. At final pathology, a malignant peripheral nerve sheath tumour (MPNST) of the pericardium with areas of chondrosarcomatous and angiosarcomatous differentiation was diagnosed...
November 10, 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/29127249/-18-f-fdg-pet-ct-for-monitoring-response-to-therapy-of-choroidal-metastasis
#4
Naghmehossadat Eshghi, John Christoforidis, Phillip Kuo
A 38-year-old woman with metastatic breast carcinoma reported seeing "halos and flashes" in her left eye. Funduscopic exam revealed an elevated mass in the choroid of the left globe consistent with metastasis. Subsequent (18)F-FDG PET/CT revealed focal uptake in the nasal aspect of the left choroid of the eye corresponding to the mass seen on the funduscopic exam. Through correlation with the PET/CT, the lesion was retrospectively identified on the MRI. (18)F-FDG PET/CT post-radiotherapy showed complete response and thus supports that this imaging modality can be used for diagnosis and monitoring response...
November 10, 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/29127248/utility-of-111-in-cl3-scintigraphy-for-differentiating-bone-marrow-reconversion
#5
Shoji Okuda, Hironori Nishibori, Hiroaki Hoshi
Indium chloride ((111)In-Cl3) scintigraphy has been used to evaluate various hematological diseases for many years. However, there have been few reports on patients with bone marrow reconversion showing high uptake in (111)In-Cl3 scintigraphy. Herein, we report a case of a 68-year-old man with esophageal cancer who underwent (18)F-FDG PET/CT for staging of the disease. (18)F-FDG PET/CT demonstrated high uptake in the first lumbar vertebral body, which was difficult to distinguish bone metastasis and bone marrow reconversion...
November 10, 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/29127247/novel-method-to-detect-and-characterize-f-18-fdg-infiltrations-in-pet-injections-a-single-institution-experience
#6
Razi Muzaffar, Sarah A Frye, Anna Mcmunn, Kelley Ryan, Ron Lattanze, Medhat M Osman
Purpose: A novel Quality Assurance/Quality Control (QA/QC) device provides Time Activity Curves (TACs) which can identify and characterize PET/CT radiotracer infiltrations during the uptake phase. The purpose of this study was to compare rates of infiltration detected by the device compared to standard PET image infiltration rates. We also aimed to assess the value of using the device to improve injection results in our center. Methods: 109 subjects were consented to the study. All subjects had passive device sensors applied to their skin near the injection site and mirrored on the contralateral arm during the entire uptake period...
November 10, 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/29127246/non-oncologic-applications-of-pet-ct-and-pet-mr-in-musculoskeletal-orthopedic-and-rheumatologic-imaging-general-considerations-techniques-and-radiopharmaceuticals
#7
Ali Gholamrezanezhad, Kyle Basques, Ali Batouli, Mojtaba Olyaie, George Matcuk, Abass Alavi, Hossein Jadvar
Positron Emission Tomography (PET) is often underutilized in the field of musculoskeletal imaging, with key reasons including the excellent performance of conventional musculoskeletal MRI, the limited spatial resolution of PET, and the lack of reimbursement for PET for non-oncologic musculoskeletal indications. However, with improvements in PET/CT and PET/MR imaging over the last decade as well as an increased understanding of the pathophysiology of musculoskeletal diseases, there is an emerging potential for PET as a primary or complementary modality in the management of rheumatologic and orthopedic patients...
November 10, 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/29127245/hypertrophic-osteoarthropathy-on-bone-scan
#8
Harleen Kaur, Mitchel A Muhleman, Helena R Balon
We present a patient with a history of lung cancer and displaying the typical pattern of hypertrophic osteoarthropathy on bone scan. We also discuss other etiologies, pathophysiology and management of this entity.
November 10, 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/29127244/imaging-of-the-thyroid-and-parathyroid-using-a-cardiac-cadmium-zinc-telluride-camera-phantom-studies
#9
Yosuke Miyazaki, Yasuhiro Kato, Akira Imoto, Kazuki Fukuchi
Purpose: Cadmium zinc telluride (CZT) detectors have recently been introduced to the field of clinical nuclear cardiology. However, the feasibility of using them for organs other than the heart remains unclear. The aim of this study was to evaluate the potential of a cardiac CZT camera to acquire thyroid and parathyroid images. We used custom-made phantoms and the currently available standard protocols for CZT, instead of a sodium-iodine scintillation (NaI) camera. Materials and Methods: Thyroid phantoms with or without parathyroid adenomas were made from agar using radiopharmaceuticals ((99m)Tc or (123)I) and imaged using CZT and NaI cameras...
November 10, 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/29127243/pelvic-meckel-s-diverticulum-mimicking-bladder-on-meckel-scan-the-impact-of-quality-control-and-technical-issues
#10
Mohsen Qutbi, Isa Neshandar Asli
Quality control and technical issues are essential for high-quality imaging. An important technical parameter of image acquisition is selecting zoom factor according to camera field-of-view dimensions and patient's body size. Here, we present a case of atypically located Meckel's diverticulum mimicking bladder on Meckel scan.
November 10, 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/29127242/gamma-camera-based-method-for-131-i-capsule-counting-an-alternate-method-to-uptake-probe-method
#11
Biju K Menon, Awasare S Uday, Baghel N Singh
The main objective of this study was to check the validity of using gamma camera as an alternate method to thyroid uptake probe, for counting 25uCi (0.925 MBq) and 50uCi (1.85 MBq) (131)I capsules before administration to thyroid patients. Methods: - 10 sets each of 25uCi (0.925 MBq) and 50uCi (1.85 MBq) (131)I capsules received from Board Of Radiation and Isotope Technology, Department Of Atomic Energy, India (BRIT, DAE) have been counted individually using thyroid uptake probe for 10 seconds following institutional protocol and also by keeping individual capsule of a set with 8cm gap between each of them ...
November 10, 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/29042474/development-of-a-pet-ct-and-pet-mri-patient-information-films-in-collaboration-with-patient-representatives-previously-treated-for-cancer
#12
Robert Shortman, John Hoath, Tina Osadolor, Pierpaolo Inge, Louise Roper, Jamshed Bomanji, Ashley M Groves
Introduction: PET/MRI and PET CT scanning carries an increased psychological burden for patients which may be improved by effective preparation prior to attendance for the procedure. We aimed to devise an online resource for patient benefit prior to PET/MRI and PET/CT scanning. Methods: With the help of patient representatives' the style and content for two patient information films was reviewed at each stage of the process to explain the patient journey. Results: Two patient information films were produced for patients undergoing PET scanning, Positive feedback from healthcare providers and users was obtained...
October 17, 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/29042473/pharmacologic-stress-testing-with-myocardial-perfusion-imaging
#13
Robert A Pagnanelli, Heidi L Camposano
Stress testing with myocardial perfusion imaging can be performed with either physical exercise or pharmacologic methods. The preferred method is physical exercise however many patients are unable to reach an adequate endpoint. As an alternative, there are various pharmacologic options available.
October 17, 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/29042472/technical-advances-in-image-guidance-of-radionuclide-therapy
#14
Casper Beijst, Britt Kunnen, Marnix Lam, Hugo de Jong
Internal radiation therapy with radionuclides (i.e. radionuclide therapy) owes its success to the many advantages over other, more conventional treatment options. One distinct advantage of radionuclide therapies is the potential to use (part of) the emitted radiation for imaging of the radionuclide distribution. The combination of diagnostic and therapeutic properties in a set of matched radiopharmaceuticals (sometimes combined in single a radiopharmaceutical) is often referred to as theranostics and allows accurate diagnostic imaging prior to therapy...
October 17, 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/29042471/measuring-patient-perception-of-quality-in-a-radiology-department-by-adapting-a-standardized-industry-proven-tool
#15
Farouk Dako, Rick Wray, Omer Awan, Rathan M Subramaniam
Introduction: Our study quantitatively measures patient perception of quality and satisfaction in a PET-CT center at the point of care using a psychometrically validated questionnaire, SERVPERF, to guide subsequent quality improvement interventions. SERVPERF is a survey instrument that captures service quality by measuring performance of various services. It has demonstrated reliability and validity across various industries including healthcare, banking, transportation, telecommunication and higher education...
October 17, 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/29042470/comparison-between-prone-and-upright-imaging-of-the-inferior-wall-using-201-tlcl-myocardial-perfusion-single-photon-emission-computed-tomography
#16
Koji Nakaya, Masahisa Onoguchi, Yoshihiro Nishimua, Keisuke Kiso, Hideki Otsuka, Yoshifumi Nouno, Takayuki Shibutani, Eisuke Yasuda
Background: Prone single photon emission computed tomography (SPECT) is suitable for evaluating the cardiac inferior wall as it suppresses attenuation artifacts from the diaphragm. The solid-state dedicated cardiac camera (D-SPECT) allows upright imaging, which can also be used to avoid attenuation artifacts from the diaphragm. We compared prone and upright imaging for inferior wall evaluation using (201)TlCl myocardial perfusion SPECT. Methods: The study targeted 45 patients. The prone imaging group included 23 subjects who underwent additional prone imaging because supine imaging indicated that the inferior wall had reduced uptake...
October 17, 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/29042469/the-importance-of-quality-control-qc-for-clinical-pet-imaging
#17
Joshua D Schaefferkoetter, Medhat M Osman, David W Townsend
No abstract text is available yet for this article.
October 17, 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/29042468/evaluation-of-step-and-shoot-and-continuous-bed-motion-pet-modes-of-acquisition-for-limited-view-organ-scans
#18
Wendy Siman, Srinivas Cheenu Kappadath
Rationale: Continuous bed motion (CBM) acquisition mode has been made commercially available in Siemens Biograph mCT positron emission tomography (PET)/computed tomography (CT) scanners. CBM mode is designed for whole-body imaging with a long scan length (multiple axial fields of view [aFOVs]) and short acquisition duration (2-3 min/aFOV). PET/CT has recently been used following (90)Y-microsphere therapy to quantify (90)Y activity distribution in the liver. Here we compared counting efficiencies along the bed-motion direction (z axis) between CBM and step-and-shoot (SS) acquisition modes for limited-view organ scans, such as (90)Y PET/CT liver studies, that have short scan lengths (≤2 aFOVs) and long acquisition durations (10-30 min/aFOV)...
October 17, 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/29042467/variability-in-heart-to-mediastinum-ratio-from-planar-123-i-mibg-images-of-a-thorax-phantom-for-6-common-gamma-camera-models
#19
Rikard Owenius, Michelle Zanette, Patrick Cella
A heart-to-mediastinum (H/M) ratio ≥1.6 on planar Iobenguane (123)I ((123)I-mIBG; AdreView) images identifies heart failure patients at low risk of experiencing an adverse cardiac event. This phase 4 study used standardized phantoms to assess the inter-camera, intra-camera, and inter-head variability in H/M ratio determinations from planar cardiac (123)I-mIBG imaging using commercially-available, dual-head gamma cameras. Methods: A fillable thorax phantom was developed to simulate the typical uptake of (123)I-mIBG...
October 17, 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/29042466/survey-of-radioactive-items-in-the-home
#20
Elizabeth E Kritzberger, Liliana Navarrete
Whether it be the sun or natural substances we encounter; we are subject to radiation every day. There are some items that can be found in the home that are either naturally radioactive or have a component containing radioactive material. This study was conducted to identify radioactive elements and to assess the exposure we receive from items that have been previously studied. We used four types of radiation detectors to obtain quantitative and qualitative information regarding the radioactive properties of items that can be found in the home like Fiestaware, smoke detectors, Brazil nuts, and granite...
October 17, 2017: Journal of Nuclear Medicine Technology
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