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Journal of Nuclear Medicine Technology

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https://www.readbyqxmd.com/read/28798229/role-of-technetium-99m-methylene-diphosphonate-spect-ct-in-the-detection-of-sacroiliitis-in-patients-with-spondyloarthropathy-comparison-with-clinical-markers-and-mri
#1
Rahul V Parghane, Baljinder Singh, Aman Sharma, Harmandeep Singh, Paramjit Singh, Anish Bhattacharya
Rationale: To evaluate the role of (99m)Tc-MDP SPECT/CT for the detection of sacroiliitis in spondyloarthopathies (SpA) and comparison with clinical markers and MRI. Methods: A total of 155 diagnosed patients (83M : 72 F; mean age 35.80±12.40 years; range 18-60 years ) with SpA as per the European Spondyloarthropathy Study Group criteria (ESSG) criteria were prospectively included All the patients were subjected to clinical evaluation (using BASDAI scoring), ESR, CRP levels, planar (99m)Tc MDP bone scintigraphy, hybrid SPECT/CT and MRI of the pelvic region...
August 10, 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/28798228/technical-peer-review-methods-and-outcomes
#2
Andrew M Keenan, Toni Cranston, Kelsey Hill, Derek J Stocker
Peer review among physicians, nurses and pharmacy staff is routine, yet uncommon in the field of nuclear medicine technology. While not a requirement of regulatory agencies, nuclear medicine technical peer review can greatly enhance the quality of patient care in both hospital and outpatient settings. To date, detailed methods for accomplishing this task have not been previously published. Methods: 19,688 nuclear medicine studies performed at a single institution over a five-year period were critically reviewed...
August 10, 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/28798227/novel-pet-tracer-68-ga-dotatate-pet-ct-can-be-alternative-imaging-method-in-patients-with-insulinomas
#3
Şadiye Altun Tuzcu, Zafer Pekkolay, Faruk Kılınç, Alpaslan Kemal Tuzcu
Insulinomas are the most common cause of hypoglycemia resulting from endogenous hyperinsulinism. The diagnosis of insulinoma is established by demonstrating inappropriately high serum insulin concentrations during a spontaneous or induced episode of hypoglycaemia. Most of the insulinomas are islet-cell tumors. They are often small (less than 2 cm), benign, and difficult to localize with current imaging techniques. The non-invasive procedures such as transabdominal ultrasonography, spiral computed tomography (CT), magnetic resonance imaging (MRI), 111-In-pentetreotide imaging, fluorine-18-L-dihydroxyphenylalanine positron emission tomography ((18)F-DOPA PET) and invasive procedures such as endoscopic ultrasonography or a selective arterial calcium stimulation test (SACST) with hepatic venous sampling can be used to show insulinomas...
August 10, 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/28798226/image-guided-combination-of-177-lu-dotatate-and-capecitabine-peptide-receptor-chemoradionuclide-therapy-in-metastatic-mediastinal-paraganglioma
#4
Abhiram G Ashwathanarayana, Chinmoy K Biswal, Ashwani Sood, Ashwin S Parihar, Rakesh Kapoor, Bhagwant R Mittal
The peptide receptor radionuclide therapy (PRRT) targets highly expressed somatostatin receptors (SSTR) shown on SSTR imaging in well-differentiated neuroendocrine tumours (NETs) with stable or partial response in majority of inoperable/metastatic NETs patients. However NETs showing increased FDG uptake carry the poor outcome with limited treatment options and role of PRRT is still unclear. Here is a case of young male patient of mediastinal paraganglioma and extensive metastatic disease showing avidity both on SSTR and FDG imaging...
August 10, 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/28705931/proof-of-concept-design-and-initial-evaluation-of-a-new-device-to-measure-gastrointestinal-transit-time
#5
Robert H Wagner, Bital Savir-Baruch, James Halama, Mukund Venu, Medhat Gabriel, Davide Bova
Chronic constipation and gastrointestinal motility disorders constitute a large part of a gastroenterology practice and represent a significant impact on patient quality of life and lifestyle. In most cases, medications are prescribed to alleviate symptoms without an objective measurement of response. Commonly used current investigations of gastrointestinal transit times are limited to radiopaque markers or electronic capsules. Repeated use of these techniques is limited due to radiation exposure or the significant cost of the devices...
July 13, 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/28705930/influence-of-attenuation-correction-by-brain-perfusion-spect-ct-simulated-abnormal-bone-structure-comparison-between-chang-and-ct-methods
#6
Takayuki Shibutani, Masahisa Onoguchi, Nanako Miyamoto, Yasushi Yamamoto, Seigo Kinuya
Introduction: Brain perfusion single photon emission computed tomography (SPECT) has physical phenomena such as attenuation, scatter, and degradation of resolution that impair accuracy on data acquisition. Chang and computed tomography (CT) methods have spread application for attenuation correction (AC) and indicate the utility of AC using a brain phantom without a bone or with a normal bone structure. However, non-uniform AC of an abnormal bone structure such as postoperative bone defect following burr-hole surgery has not yet evaluated...
July 13, 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/28705929/use-of-tc-99m-tilmanocept-as-a-single-agent-for-sentinel-lymph-node-identification-in-breast-cancer-a-retrospective-pilot-study
#7
Jonathan Takei Unkart, Anne Marie Wallace
Introduction: Tc-99m tilmanocept (TcTM) received recent FDA-approval for lymphatic mapping. However, no prior studies have evaluated the use of TcTM as a single agent in sentinel lymph node (SLN) biopsy in breast cancer. Methods: We executed this retrospective, pilot study to assess the ability of TcTM to identify sentinel nodes as a single agent in clinically node-negative breast cancer patients. Patients received a single, intradermal injection overlying the tumor of either 0.5 mCi TcTM the day-of surgery or 2...
July 13, 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/28705928/miniaturized-radiochemical-purity-testing-for-99m-tc-hmpao-99m-tc-hmdp-and-99m-tc-tetrofosmin
#8
Ana de la Fuente, Roberta Zanca, Angela Gabriella Cataldi, Roberto Boni, Martina Sollini, Elena Lazzeri, Giuliano Mariani, Paola Anna Erba
Quick methods are functional in clinical practice in order to ensure the fastest availability of radiopharmaceuticals. For this purpose, we investigated the radiochemical purity of the widely used (99m)Tc-HMDP (hydroxymethylene diphosphonate), (99m)Tc-HMPAO (hexamethylpropyleneamine oxime) and (99m)Tc-Tetrofosmin by reducing time as compared to the manufacturer's method. Methods: We applied a miniaturized chromatographic method with a reduced strip development from 18 cm to 9 cm for all three radiopharmaceuticals...
July 13, 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/28705927/incidence-of-brain-metastases-on-follow-up-18-f-fdg-pet-ct-scans-of-non-small-cell-lung-cancer-patients-should-we-include-the-brain
#9
Emily Nia, Linda Garland, Naghmehossadat Eshghi, Benjamin Nia, Ryan Avery, Phillip Kuo
PURPOSE: The brain is the most common site of distant metastasis from lung cancer. Thus MRI of the brain at initial staging is routinely performed, but if this exam is negative a follow-up exam is often not performed. This study evaluates the incidence of asymptomatic brain metastases in non-small cell lung cancer patients detected on follow-uP(18)F- FDG PET/CT scans. MATERIALS AND METHODS: In this IRB approved retrospective review, all vertex to thigh (18)F- FDG PET/CT scans in patients with all subtypes of lung cancer from August 2014 to August 2016 were reviewed...
July 13, 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/28705926/incidental-nuclear-cardiology-findings-in-the-interpretation-of-myocardial-spect-imaging
#10
Razi Muzaffar, Osama Raslan, Fatma Ahmed, Leonard Goldfarb, Barbara Sterkel, Medhat M Osman
Myocardial SPECT imaging plays a crucial role in the diagnosis of coronary artery disease providing a non-invasive tool to monitor ischemia and infarction. The findings can have a profound impact in diagnosing and managing these patients. However, non-cardiac incidental findings on myocardial SPECT images can also impact the management of these patients. These non-cardiac subtleties are most often detected on the raw rotating images which are often overlooked. The intent of this pictorial essay is to illustrate several subtle non-cardiac abnormalities within nuclear cardiac imaging which can have an impact on patient management and follow-up...
July 13, 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/28611234/complex-regional-pain-syndrome-diagnosed-with-three-phase-bone-scan
#11
Harleen Kaur, Mitchel A Muhleman, Helena R Balon
In this report, we present a case of complex regional pain syndrome in a 55-year-old female in whom the diagnosis was made based on the bone scan findings. We also discuss the typical and atypical scintigraphic presentations of this entity, including pathophysiology and management.
June 13, 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/28611233/splenic-uptake-on-bone-scan
#12
Harleen Kaur, Mitchel Muhleman, Helena R Balon
We present a patient with splenic uptake on bone scan that was due to sickle cell disease. We also discuss other etiologies for this finding.
June 13, 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/28611232/nuclear-imaging-in-a-cardiac-paraganglioma
#13
Nada H Almenieir, Shawn Karls, Vilma Derbekyan, Robert Lisbona
We report a case of a cardiac paraganglioma in the right atrioventricular groove, where the use of different nuclear medicine studies aided in the diagnosis and management.
June 13, 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/28611231/validation-of-the-left-ventricular-ejection-fraction-with-iq-spect-system-in-small-heart-patients
#14
Hiroto Yoneyama, Takayuki Shibutani, Takahiro Konishi, Asuka Mizutani, Hashimoto Ryosuke, Masahisa Onoguchi, Koichi Okuda, Shinro Matsuo, Kenichi Nakajima, Kinuya Seigo
The IQ-SPECT system equipped with a multifocal (SMARTZOOM) collimator using an ordered subset conjugate gradient minimization (OSCGM) algorithm reduces the acquisition time of myocardial perfusion imaging (MPI) compared to conventional gamma cameras equipped with low-energy high-resolution (LEHR) collimators. We compared IQ-SPECT with a conventional single-photon emission computed tomography (SPECT) system for estimating the left ventricular ejection fraction (LVEF) in small-heart patients. Methods: The study group consisted of 98 consecutive patients who underwent a 1-day stress-rest MPI study with a (99m)Tc-labeled agent for preoperative risk assessment...
June 13, 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/28576933/the-value-of-experience-lessons-learned-and-pearls-of-wisdom-gathered
#15
EDITORIAL
Norman E Bolus
No abstract text is available yet for this article.
June 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/28576932/advancing-our-profession-in-exciting-and-challenging-times
#16
Sara G Johnson
No abstract text is available yet for this article.
June 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/28576931/erratum
#17
(no author information available yet)
No abstract text is available yet for this article.
June 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/28473461/nuclear-medicine-technologists-perception-and-current-assessment-of-quality-a-society-of-nuclear-medicine-and-molecular-imaging-technologist-section-survey
#18
REVIEW
April Mann, Mary Beth Farrell, Jessica Williams, Danny Basso
In 2015, the Society of Nuclear Medicine and Molecular Imaging Technologist Section (SNMMI-TS) launched a multiyear quality initiative to help prepare the technologist workforce for an evidence-based health-care delivery system that focuses on quality. To best implement the quality strategy, the SNMMI-TS first surveyed technologists to ascertain their perception of quality and current measurement of quality indicators. Methods: An internet survey was sent to 27,989 e-mail contacts. Questions related to demographic data, perceptions of quality, quality measurement, and opinions on the minimum level of education are discussed in this article...
June 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/28408704/changes-in-patterns-of-99m-tc-macroaggregated-albumin-use-between-2000-and-2015
#19
James A Ponto
Since the early 2000s, the method of evaluating pulmonary embolism has shifted from (99m)Tc-macroaggregated albumin (MAA) perfusion lung scans to CT angiography. (99m)Tc-MAA continues to be applied for patients with contraindications to CT angiography and for other uses. A reduced number of (99m)Tc-MAA particles is administered to patients with pulmonary hypertension or other risk factors. This study assessed the changing patterns of (99m)Tc-MAA use between 2000 and 2015 at a single institution by comparing snapshots of the procedures performed in those two years...
June 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/28408703/accuracy-of-82-rb-pet-ct-myocardial-perfusion-imaging-with-regadenoson-stress-including-3-year-clinical-outcomes
#20
Michael D Brophey, Irfan M Farukhi, Rosinda Castanon, Rosinda DeLaPena, Ledjona Bradshaw, Subhash Banerjee
The purpose of this study was to determine the clinical accuracy of (82)Rb PET/CT myocardial perfusion imaging (MPI) when performed with regadenoson stress in a U.S. Department of Veterans Affairs (VA) population of patients. Methods: The initial cohort of 480 patients undergoing vasodilator PET MPI with regadenoson stress at our institution from September 2009 through July 2010 was closely tracked for short-term outcomes based on correlation with invasive coronary catheterization. Long-term outcomes were determined by major adverse cardiac event rates based on data extraction from the electronic medical record and grouped by summed stress score (SSS) for a 3-y period...
June 2017: Journal of Nuclear Medicine Technology
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