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Journal of Nuclear Medicine Technology

Michael Bornholdt, Kayla Woelfel, Ping Fang, Mark Jacobson, Joseph Hung
The objective of this study was to develop instant thin layer chromatography (ITLC) conditions for the determination of radiochemical purity (RCP) of 68 Ga-DOTATATE in a shorter time period than those stated in the NETSPOT (Advanced Accelerator Applications, Saint-Genis-Pouilly, France; AAA) kit package insert (PI). A faster ITLC system is needed to reduce the current 48-50 minutes development time; so that (1) more radioactivity is available for single patient use as the generator ages and (2) wait times are shorter in the event of kit failure...
May 3, 2018: Journal of Nuclear Medicine Technology
Geoffrey M Currie
No abstract text is available yet for this article.
May 3, 2018: Journal of Nuclear Medicine Technology
Ismet Sarikaya, Zaina Al-Banna, Ali Baqer
Parallax error is a pitfall of pinhole scintigraphy which causes mislocalization of the objects. It is important to notice this error on pinhole thyroid and parathyroid scintigraphy and obtain additional images with parallel-hole collimator to accurately determine the upper and lower margins of large goiter and nodules and location of the ectopic thyroid tissue and parathyroid adenomas. In this teaching case report we wanted to revisit pinhole parallax error, present pinhole and SPECT/CT images of a case with large hyperactive thyroid nodule and review the literature and potential solutions to this important problem...
May 3, 2018: Journal of Nuclear Medicine Technology
Omer Awan, Farouk Dako
No abstract text is available yet for this article.
May 3, 2018: Journal of Nuclear Medicine Technology
Geoffrey M Currie
Pharmacology principles provide key understanding that underpins the clinical and research roles of nuclear medicine practitioners. This article is the second in a series of articles that aims to enhance the understanding of pharmacological principles relevant to nuclear medicine. This article will build on the introductory concepts, terminology and principles of pharmacodynamics explored in the first article in the series. Specifically, this article will focus on the basic principles associated with pharmacokinetics...
May 3, 2018: Journal of Nuclear Medicine Technology
Anthony Wayne Knight
Given the close interpersonal nature of the student-clinical instructor (CI) relationship and the unpredictable and often stressful clinical environment in which they interact with one another, it is extremely important that clinical instructors understand how their behavior directly affects their students' motivation to engage in educationally important clinical activities. This article presents a review of the motivation literature grounded in self-determination theory with the goal of providing the reader insight into how clinical instructor psychological need-supporting/thwarting behaviors affect student clinical engagement...
May 3, 2018: Journal of Nuclear Medicine Technology
Maria Camila Garcia Toro, Joshua P Schlegel, Carlos H C Giraldo
We report the synthesis of radioactive gold nanoparticles in a single step process with appropriate activity and size to be used in cancer treatment and diagnosis. Methods: A 2 mM solution of gold chloride (HAuCl4), 1 mM of polyvinylpyrrolidone (PVP, M.W: 360,000), and 60 mM of 2-propanol was prepared in deionized water. Seven different samples of the solution were irradiated in a total neutron flux of 7.45 x 1012 n/cm2 s in a research reactor for 0.5, 1, 3, 5, 10, 30, and 60 minutes. The resulting nanoparticles were characterized for morphology and chemical composition using a Transmission Electron Microscopy (TEM) and ImageJ...
May 3, 2018: Journal of Nuclear Medicine Technology
April Mann, Mario DiDea, France Fournier, Daniel Tempesta, Jessica Williams, Norman LaFrance
As the healthcare environment continues to change and morph into a system focusing on increased quality and evidence-based outcomes, nuclear medicine technologists must be reminded they play a critical role in achieving high quality interpretable images used to drive patient care, treatments and best possible outcomes. A survey performed by the Quality Committee, Society of Nuclear Medicine and Molecular Imaging-Technologist Section demonstrated a clear knowledge gap exists amongst technologists regarding their understanding of quality, how it is measured, and how it should be achieved throughout all practicing technologists despite role and education level...
May 3, 2018: Journal of Nuclear Medicine Technology
Anna Eshghi, Robert Klein, Naghmehossadat Eshghi, Phillip Hsin Kuo
A 21-year-old man presented with polyuria and polydipsia and was discovered to have diabetes insipidus due to eosinophilic granuloma of the hypothalamus. 18 F FDG-PET/CT for metastatic work-up revealed an intensely FDG avid hypothalamic mass and no other sites of disease.
May 3, 2018: Journal of Nuclear Medicine Technology
Geoffrey M Currie, Catherine J Thomas
Program development and review is a central part of institutional and industry quality assurance. Traditional approaches, while well established, present a number of barriers that could undermine process integrity and quality outcomes. Here a new approach to program development and design is explored with the goal of enhancing outcomes for students and institutions.
May 3, 2018: Journal of Nuclear Medicine Technology
Naoki Hashimoto, Keishin Morita, Yuji Tsutsui, Kazuhiko Himuro, Shingo Baba, Masayuki Sasaki
Recent advancements in clinical PET/CT scanners have improved the detectability of small lesions. However, the ideal reconstruction parameters for detecting small lesions have not yet been sufficiently clarified. The purpose of this study was to investigate the detectability of the sub-centimeter spheres using a clinical PET/CT scanner. Methods: We used a Biograph mCT scanner to obtain the data of a NEMA body phantom consisting of 6 small spheres ( inner diameters: 4.0, 5.0, 6.2, 7.9, 10 and 37 mm ) containing18 F solution...
March 29, 2018: Journal of Nuclear Medicine Technology
Naghmehossadat Eshghi, Linda Garland, Emily Saghar Nia, Robert Betancourt, Elizabeth Krupinski, Phillip H Kuo
Objective: For patients undergoing immunotherapy with nivolumab for lung cancer, determine if increased18 F-FDG uptake in the thyroid gland predicts development of thyroiditis with subsequent hypothyroidism. Secondarily, determine if18 F-FDG uptake in the thyroid gland correlates with administered cycles of nivolumab. Materials and Methods: Retrospective chart review over 2 years found 18 lung cancer patients treated with nivolumab and with18 F-FDG PET/CT scans pre- and during therapy. Standardized uptake value (SUV) mean and maximum and total lesion glycolysis (TLG) of the thyroid gland were measured...
March 29, 2018: Journal of Nuclear Medicine Technology
Jennifer L Prekeges
This article describes a workshop offered annually by the radiation and imaging programs at Bellevue College, Bellevue, WA. The workshop provides an educator's perspective to those who teach students in our clinical internships. An outline of the workshop is given as are reasons for its ongoing success.
March 29, 2018: Journal of Nuclear Medicine Technology
Trygve Halsne, Ebba Glørsen Müller, Ann-Eli Spiten, Alexander Gul Sherwani, Lars Tore Gyland Mikalsen, Mona-Elisabeth Rootwelt-Revheim, Caroline Stokke
Due to better precision and intercompatibility, the use of lean body mass (LBM) as mass estimate in the calculation of standardized uptake values (SUV) has become more common in research and clinical studies today. Thus, the equations deciding this quantity have to be verified in order to choose the ones that best represents the actual body composition. Methods: LBM was calculated for 44 patients examined with18 F-FDG PET/CT scans by means of James' and Janmahasatians' sex specific predictive equations and the results validated using a CT based methods...
March 29, 2018: Journal of Nuclear Medicine Technology
Ismet Sarikaya, Abdelhamid Elgazzar, Ali Sarikaya, Naheel Alnafisi, Saud Alenezi
On radionuclide somatostatin receptor (SSTR) imaging studies spleen shows very high uptake which is a physiological finding. Reducing intensity of the image settings helps to better assess the distribution of radiotracer in the spleen. In our routine studies we incidentally recognized that Gallium-68 (Ga-68) DOTANOC positron emission tomography (PET) provides higher resolution splenic images as compared to In-111 Octreotide single photon emission computed tomography (SPECT). Autoradiography and immunohistochemistry studies have shown that SSTRs are mainly located in the red pulp of the spleen...
March 29, 2018: Journal of Nuclear Medicine Technology
Thuy D Tran, Lacey R Ellingson, Tiffinee N Swanson, Courtney M Solberg, Michael K O'Connor, Carrie B Hruska
Objective: At our institution, MBI is performed with 300 MBq Tc-99m sstamibi for all patients. For some nuclear medicine procedures, administered activity or imaging time is increased for patients of larger size in order to obtain adequate counts. Our objective was to assess whether uptake of Tc-99m sestamibi in the breast is influenced by patient size. Methods: Records from patients who underwent a clinical MBI examination between July - November 2016 were reviewed. Those in whom our standard injection and preparation techniques were followed were included in the analysis [3,4]...
March 29, 2018: Journal of Nuclear Medicine Technology
Anil Kumar Pandey, Vishali Dhiman, Akshima Sharma, Sreedharan Thankarajan ArunRaj, Vivek Baghel, Chetan Patel, Param Dev Sharma, Chandrasekhar Bal, Rakesh Kumar
The bone scintigraphic image might exceed the dynamic range (the ratio between the highest and the lowest brightness a monitor is capable of displaying) of display monitor. In this case, a high intensity area, and loss of the details of other structures in the displayed image makes the clinical interpretation a challenging task. We have investigated the role of intensity transformation function for enhancement of these types of images. Methods: Forty high dynamic range bone scintigraphic images were processed using intensity transformation (IT) function...
March 29, 2018: Journal of Nuclear Medicine Technology
Geoffrey M Currie
There is an emerging need for greater understanding of pharmacology principles amongst technical staff. Indeed, the responsibility of dose preparation and administration, under any level of supervision, demands foundation understanding of pharmacology. This is true for radiopharmaceuticals, contrast media and pharmaceutical interventions / adjunctive medications. Regulation around the same might suggest a need to embed pharmacology theory in undergraduate education programs and there is a need to disseminate that same foundation understanding to practicing clinicians...
March 29, 2018: Journal of Nuclear Medicine Technology
David R Hansberry, Kush Shah, Nitin Agarwal, Sung M Kim, Charles M Intenzo
The Internet is a major source of healthcare information for patients. The American Medical Association and National Institutes of Health recommend that consumer healthcare websites be written between a 3rd and 7th grade level. The purpose of this study is to evaluate the level of readability of patient education websites pertaining to nuclear medicine. Methods: Ten search terms were Googled and the top 10 links for each term were collected and analyzed for their level of readability using 10 well-established readability scales...
February 2, 2018: Journal of Nuclear Medicine Technology
Mary Beth Farrell
No abstract text is available yet for this article.
February 2, 2018: Journal of Nuclear Medicine Technology
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