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Journal of Nuclear Medicine Technology

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https://www.readbyqxmd.com/read/28154021/compliance-with-gastric-emptying-scintigraphy-guidelines-a-report-from-the-intersocietal-accreditation-commission-database
#1
Mary Beth Farrell, Maria Costello, Jena-Lee D McKee, Leonie M Gordon, Lorraine M Fig
: Many variables can influence the results of the gastric emptying scintigraphy (GES). A lack of methodologic standardization may cause variability, limit comparisons, and decrease the credibility of the test. To address this, in 2009, the SNMMI published Procedure Guideline for Adult Solid-Meal Gastric-Emptying Study 3.0 which describes a standardized, validated GES protocol. Laboratories must closely follow the consensus protocol to provide valid and standardized results and improve patient care...
February 2, 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/28154020/comparison-of-performance-of-improved-serum-estimators-of-gfr-to-tc-99m-dtpa-gfr-methods-in-patients-with-hepatic-cirrhosis
#2
Zaid Haddadin, Vivian Lee, Christopher Conlin, Lei Zhang, Kristi Carlston, Glen Morrell, Daniel Kim, John M Hoffman, Kathryn A Morton
RATIONALE: GFR measurements are critical in patients with hepatic cirrhosis, but potentially erroneous when based on serum creatinine. New equations for estimated GFR (eGFR) have shown variable performance in cirrhotics, possibly due to inaccuracies in reference methods for measured GFR (mGFR). The primary objective was to compare the performance of 4 improved eGFR equations to a 1-compartment, 2-sample plasma slope intercept (99m)Tc-DTPA mGFR method to determine whether any of the eGFR calculations could replace plasma (99m)Tc-DTPA mGFR in patients with cirrhosis...
February 2, 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/28154019/mib1-index-stratified-assessment-of-dual-tracer-pet-ct-with-68ga-dotatate-and-18f-fdg-and-multimodality-anatomical-imaging-in-metastatic-net-of-unknown-primary-cup-net-scheduled-for-prrt
#3
Nikita Sampathirao, Sandip Basu
AIM: Comparative assessment of dual tracer PET/CT ((68)Ga-DOTATATE and (18)F-FDG) and multimodality anatomical imaging in studying CUP-NETs scheduled for PRRT for: (i) divergence of tracer uptake on dual tracer PET/CT, (ii) detection of primary and (iii) overall lesion detection vis-a-vis tumor proliferation index (Mib1/Ki-67). MATERIALS AND METHODS: Fifty-one patients of CUP-NETs (M:F=25:26, age:22-74 years), histopathologically proven and thoroughly investigated with conventional imaging modalities (USG, CT/ceCT, MRI and EUS, wherever applicable), were retrospective analyzed...
February 2, 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/28154018/hepatic-lesions-in-a-cirrhotic-liver-primary-or-metastases
#4
Lorenzo Mannelli, Serena Monti, Verena Grieco, Manuela Matesan
Although prior studies showed that patients with cirrhosis have a lower risk of developing liver metastases, appropriate work-up of incidental liver masses in cirrhotic liver is important for a correct diagnosis. Here we present a case of newly diagnosed liver cirrhosis with multifocal hepatic lesions which was initially categorized as LI-RADS 5 lesions. Scintigraphy with Octreoscan indicate a suspicious thyroid nodule, later confirmed to represent a medullary thyroid carcinoma lesion. The most relevant imaging finding of this rare form of thyroid malignancy, are reviewed in this presentation...
February 2, 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/28154017/reply-survey-on-the-use-of-nuclear-renal-imaging-in-the-united-states
#5
Norman Bolus
No abstract text is available yet for this article.
February 2, 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/28154016/letter-survey-on-the-use-of-nuclear-renal-imaging-in-the-united-states
#6
Raghuveer K Halkar, Andrew T Taylor
No abstract text is available yet for this article.
February 2, 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/28154015/potential-ways-to-address-shortage-situations-of-mo-99-tc-99m
#7
Leah Filzen, Lacey Ellingson, Andrew Paulsen, Joseph Hung
: Technetium 99m (Tc-99m) is the most common radioisotope used in nuclear medicine, which is produced in a nuclear reactor from the decay of molybdenum-99 (Mo-99). There are only a few aging nuclear reactors around the world that produce Mo-99 and one of the major contributors, the NRU (National Research Universal, Canada), will cease production on October 31, 2016. The NRU produces approximately 40% of the world's Mo-99 supply, so with its impending shut down, shortages of Mo-99/Tc-99m are expected...
February 2, 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/27920188/the-nuclear-medicine-advanced-associate-a-strategic-decision-and-future-direction
#8
Sara G Johnson
No abstract text is available yet for this article.
December 2016: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/27920187/another-year-in-the-world-of-nuclear-medicine-technology
#9
EDITORIAL
Norman E Bolus
No abstract text is available yet for this article.
December 2016: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/27920186/erratum
#10
(no author information available yet)
No abstract text is available yet for this article.
December 2016: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/27920185/myocardial-perfusion-imaging-2016-quality-safety-and-dose-optimization
#11
LisaAnn Trembath
No abstract text is available yet for this article.
December 2016: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/27920184/the-highlights-lectures-1981-2009
#12
Heather Poulin
No abstract text is available yet for this article.
December 2016: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/27834726/duodenal-obstruction-on-99mtc-disida-cholescintigraphy-a-noninvasive-approach-to-bowel-obstruction-diagnosis
#13
REVIEW
Asif A Fakhri, Aun Hussain, Abbas Taiyebi, Amena Fatima Fakhri
We present a case study of a 56-y-old man who was admitted with acute abdominal pain and was found to have retroperitoneal hematoma from a ruptured duodenal aneurysm. (99m)Tc-diisopropyliminodiacetic acid cholescintigraphy showed incidental absent transit of radiotracer into the distal duodenum and severe enterogastric reflux, thought to be secondary to duodenal obstruction from the hematoma. Findings were confirmed on esophagogastroduodenoscopy, and the patient improved after subsequent gastrojejunostomy.
December 2016: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/27834724/validation-of-a-single-time-point-measurement-of-total-abdominal-counts-to-simplify-small-bowel-and-colon-transit-analyses
#14
Alan H Maurer, Rahul Parupalli, Perry Orthey, Henry P Parkman
: The Society of Nuclear Medicine and Molecular Imaging and European Association of Nuclear Medicine procedure guide on gastrointestinal transit currently indicates that the mean of total abdominal counts of 7 time points (0-360 min) is used to define the total abdominal counts for bowel transit studies. The purpose of this study was to investigate the variability of total abdominal counts during the initial 6 h of bowel transit and to determine whether a simplified, single-time-point measurement can be used...
December 2016: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/27834723/evolution-of-papillary-thyroid-carcinoma-into-tall-cell-variant-and-tenis-syndrome
#15
REVIEW
Avik Chakraborty, S V Kane, Yogita Pawer, Sandip Basu
We herein report an unusual case of a 55-y-old woman with papillary carcinoma of the thyroid, who presented with multiple recurrences, with its subsequent evolution to tall cell variant and thyroglobulin-elevated negative iodine scintigraphy (TENIS) syndrome. During the course of the disease the lesions became non-iodine-concentrating with an increased proportion of tall cells and evidence of local and distant metastasis. Molecular analysis of the tissue specimen demonstrated BRAF(V600E) and I582 M mutations along with upregulation of tumor markers in metastatic tissue...
December 2016: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/27789752/survey-on-the-use-of-nuclear-renal-imaging-in-the-united-states
#16
REVIEW
Kelly D Archer, Norman E Bolus
: Throughout the years, the role of nuclear medicine departments in the care of renal patients has changed as a result of technologic advancements and other factors. This study evaluated the current role of nuclear renal imaging. METHODS: A survey was generated with questions about patient populations, the clinical indications most often seen, radiopharmaceutical use, measurement techniques, the average number of scans completed, and medical center/transplant team affiliations...
December 2016: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/27789751/nuclear-imaging-in-metastatic-paraganglioma
#17
REVIEW
Rohit Kedia, Neil Hansen, Whitney Goldner
Paragangliomas associated with mutations of the SDHD gene can occasionally result in distant metastasis. Diagnosis can be difficult, and nuclear imaging is used to evaluate the case further. Not all tumors are alike; nuclear avidity may differ. We present a case in which metastatic paraganglioma caused by mutations of the SDHD gene was negative on (123)I-metaiodobenzylguanidine scintigraphy and positive on (111)In-labeled octreotide scintigraphy. This situation presents an opportunity for a novel therapeutic approach toward metastatic paraganglioma using targeted peptide receptor radionuclide therapy...
December 2016: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/27789750/metabolic-signature-on-18f-fdg-pet-ct-her2-status-and-survival-in-gastric-adenocarcinomas
#18
Romulo Celli, Monica Colunga, Natalie Patel, Mehdi Djekidel, Dhanpat Jain
: The human epidermal growth factor 2 (HER2)-overexpressing (HER2-positive [HER2+]) gastric (GC) and gastroesophageal junction adenocarcinomas (GEJC) are felt to represent a more aggressive form of disease, which may correlate to increased metabolic activity. Whether tumor SUVmax measured by (18)F-FDG PET/CT could be a preoperative parameter used to predict HER2 status of GC/GEJC is unknown. METHODS: Pathology reports of HER2+ GC/GEJC biopsies and resections from 31 patients were reviewed and compared with HER2-negative (HER2-) cases distributed evenly over the same time period...
December 2016: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/27634983/the-necessity-of-using-heparin-in-the-ultratag-rbc-kit-when-tagging-blood-for-a-nuclear-medicine-study
#19
Sarah R Pigmon, Kara D Weatherman, Nicholas C Brehl, Cybil J Nielsen
: The purpose of this research was to evaluate the need to use heparin when preparing an UltraTag red blood cell (RBC) kit for a nuclear medicine study. METHODS: Nonheparinized blood samples (n = 15) and heparinized blood samples (n = 15) were added to UltraTag RBC kits. The samples were examined for macroscopic blood clotting and microscopic platelet clumping. As a control, samples with heparin (n = 15) and without heparin (n = 15) were used to help evaluate the effectiveness of the anticoagulant properties within the UltraTag RBC kit (sodium citrate) and whether those properties played a role in preventing clots or clumps...
December 2016: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/27634982/177lu-dotatate-prrt-in-recurrent-skull-base-phosphaturic-mesenchymal-tumor-causing-osteomalacia-a-potential-application-of-prrt-beyond-neuroendocrine-tumors
#20
REVIEW
Sandip Basu, Preeti Fargose
The potential of peptide receptor radionuclide therapy (PRRT) is described in a case of recurrent inoperable phosphaturic mesenchymal tumor causing osteomalacia in the left basiocciput, for which the patient had undergone surgery twice previously. After one cycle of PRRT, there was good symptomatic improvement, with a modest reduction in uptake on both (68)Ga-DOTATATE PET/CT and (18)F-FDG PET/CT suggesting a favorable response. Hence, treatment with a second cycle was considered. Being somatostatin receptor-avid, this rare group of tumors when inoperable or recurrent may potentially be targeted with PRRT...
December 2016: Journal of Nuclear Medicine Technology
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