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Acta Biotheoretica

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https://www.readbyqxmd.com/read/27853896/discrete-mesh-approach-in-morphogenesis-modelling-the-example-of-gastrulation
#1
J Demongeot, A Lontos, E Promayon
Morphogenesis is a general concept in biology including all the processes which generate tissue shapes and cellular organizations in a living organism. Many hybrid formalizations (i.e., with both discrete and continuous parts) have been proposed for modelling morphogenesis in embryonic or adult animals, like gastrulation. We propose first to study the ventral furrow invagination as the initial step of gastrulation, early stage of embryogenesis. We focus on the study of the connection between the apical constriction of the ventral cells and the initiation of the invagination...
November 16, 2016: Acta Biotheoretica
https://www.readbyqxmd.com/read/27837289/wound-healing-and-scale-modelling-in-zebrafish
#2
F Caraguel, N Bessonov, J Demongeot, D Dhouailly, V Volpert
We propose to study the wound healing in Zebrafish by using firstly a differential approach for modelling morphogens diffusion and cell chemotactic motion, and secondly a hybrid model of tissue regeneration, where cells are considered as individual objects and molecular concentrations are described by partial differential equations.
November 11, 2016: Acta Biotheoretica
https://www.readbyqxmd.com/read/27785584/interactions-between-the-cross-shore-structure-of-small-pelagic-fish-population-offshore-industrial-fisheries-and-near-shore-artisanal-fisheries-a-mathematical-approach
#3
Rachid Mchich, Timothée Brochier, Pierre Auger, Patrice Brehmer
This work presents a mathematical model describing the interactions between the cross-shore structure of small pelagic fish population an their exploitation by coastal and offshore fisheries. The complete model is a system of seven ODE's governing three stocks of small pelagic fish population moving and growing between three zones. Two types of fishing fleets are inter-acting with the fish population, industrial boats, constrained to offshore area, and artisanal boats, operating from the shore. Two time scales were considered and we use aggregation methods that allow us to reduce the dimension of the model and to obtain an aggregated model, which is a four dimension one...
October 26, 2016: Acta Biotheoretica
https://www.readbyqxmd.com/read/27770318/preface
#4
Hermine Biermé, Jean-Pierre Françoise, Rémy Guillevin, Alain Miranville
No abstract text is available yet for this article.
October 21, 2016: Acta Biotheoretica
https://www.readbyqxmd.com/read/27770317/basin-of-attraction-of-solutions-with-pattern-formation-in-slow-fast-reaction-diffusion-systems
#5
B Ambrosio, M A Aziz-Alaoui
This article is devoted to the characterization of the basin of attraction of pattern solutions for some slow-fast reaction-diffusion systems with a symmetric property and an underlying oscillatory reaction part. We characterize some subsets of initial conditions that prevent the dynamical system to evolve asymptotically toward solutions which are homogeneous in space. We also perform numerical simulations that illustrate theoretical results and give rise to symmetric and non-symmetric pattern solutions. We obtain these last solutions by choosing particular random initial conditions...
October 21, 2016: Acta Biotheoretica
https://www.readbyqxmd.com/read/27770316/can-fishing-pressure-invert-the-outcome-of-interspecific-competition-the-case-of-the-thiof-and-of-the-octopus-along-the-senegalese-coast
#6
Thuy Nguyen-Phuong, Doanh Nguyen-Ngoc, Pierre Auger, Sidy Ly, Didier Jouffre
We present a mathematical model of two competing marine species that are harvested. We consider three models according to different levels of complexity, without and with species refuge and density-independent and density-dependent species movement between fishing area and refuge. We particularly study the effects of the fishing pressure on the outcome of the competition. We focus on conditions that allow an inferior competitor to invade as a result of fishing pressure. The model is discussed in relationship to the case of the thiof and the octopus along the Atlantic West African coast...
October 21, 2016: Acta Biotheoretica
https://www.readbyqxmd.com/read/27770315/effects-of-behavioural-strategy-on-the-exploitative-competition-dynamics
#7
Doanh Nguyen-Ngoc, Thuy Nguyen-Phuong
We investigate a system of two species exploiting a common resource. We consider both abiotic (i.e. with a constant resource supply rate) and biotic (i.e. with resource reproduction and self-limitation) resources. We are interested in the asymmetric competition where a given consumer is the locally superior resource exploiter (LSE) and the other is the locally inferior resource exploiter (LIE). They also interact directly via interference competition in the sense that LIE individuals can use two opposite strategies to compete with LSE individuals: we assume, in the first case, that LIE uses an avoiding strategy, i...
October 21, 2016: Acta Biotheoretica
https://www.readbyqxmd.com/read/27761675/a-greedy-algorithm-for-brain-mri-s-registration
#8
Clément Chesseboeuf
This document presents a non-rigid registration algorithm for the use of brain magnetic resonance (MR) images comparison. More precisely, we want to compare pre-operative and post-operative MR images in order to assess the deformation due to a surgical removal. The proposed algorithm has been studied in Chesseboeuf et al. ((Non-rigid registration of magnetic resonance imaging of brain. IEEE, 385-390. doi: 10.1109/IPTA.2015.7367172 , 2015), following ideas of Trouvé (An infinite dimensional group approach for physics based models in patterns recognition...
October 19, 2016: Acta Biotheoretica
https://www.readbyqxmd.com/read/27757742/recursive-model-identification-for-the-evaluation-of-baroreflex-sensitivity
#9
Virginie Le Rolle, Alain Beuchée, Jean-Paul Praud, Nathalie Samson, Patrick Pladys, Alfredo I Hernández
A method for the recursive identification of physiological models of the cardiovascular baroreflex is proposed and applied to the time-varying analysis of vagal and sympathetic activities. The proposed method was evaluated with data from five newborn lambs, which were acquired during injection of vasodilator and vasoconstrictors and the results show a close match between experimental and simulated signals. The model-based estimation of vagal and sympathetic contributions were consistent with physiological knowledge and the obtained estimators of vagal and sympathetic activities were compared to traditional markers associated with baroreflex sensitivity...
October 18, 2016: Acta Biotheoretica
https://www.readbyqxmd.com/read/27738842/a-mathematical-model-for-alternation-of-polygamy-and-parthenogenesis-stability-versus-efficiency-and-analogy-with-parasitism
#10
Evariste Sanchez-Palencia, Philippe Lherminier, Jean-Pierre Françoise
The present work is a contribution to the understanding of the sempiternal problem of the "burden of factor two" implied by sexual reproduction versus asexual one, as males are energy consumers not contributing to the production of offspring. We construct a deterministic mathematical model in population dynamics where a species enjoys both sexual and parthenogenetic capabilities of reproduction and lives on a limited resource. We then show how polygamy implies instability of a parthenogenetic population with a small number of sexually born males...
October 13, 2016: Acta Biotheoretica
https://www.readbyqxmd.com/read/27718031/influence-of-antithrombin-on-the-regimes-of-blood-coagulation-insights-from-the-mathematical-model
#11
Anass Bouchnita, Tatiana Galochkina, Vitaly Volpert
Blood coagulation is regulated through a complex network of biochemical reactions of blood factors. The main acting enzyme is thrombin whose propagation in blood plasma leads to fibrin clot formation. Spontaneous clot formation is normally controlled through the action of different plasma inhibitors, in particular, through the thrombin binding by antithrombin. In the current study we develop a mathematical model of clot formation both in quiescent plasma and in blood flow and determine the analytical conditions on the antithrombin concentration corresponding to different regimes of blood coagulation...
October 7, 2016: Acta Biotheoretica
https://www.readbyqxmd.com/read/27704263/mathematical-model-of-the-dynamics-of-fish-waterbirds-and-tourists-in-the-djoudj-national-park-senegal
#12
Oumar Diop, Abdou Sène
In the present paper, we propose and analyze a harvested predator-prey model that incorporates the dynamics of tourists in the Djoudj National Park of Birds, Senegal. The model describes the impact of migration of waterbirds and seasonal fishing on the global coexistence of species in the site of the Djoudj. By the Mahwin continuation theorem of coincidence degree theory, we investigate the existence of a positive periodic solution. The global asymptotic stability is discussed by constructing a suitable Lyapunov functional...
October 4, 2016: Acta Biotheoretica
https://www.readbyqxmd.com/read/27699504/exploring-darwinian-worlds-from-darwin-to-the-extended-synthesis-essay-review-of-t-heams-p-huneman-g-lecointre-and-m-silberstein-eds-handbook-of-evolutionary-thinking-in-the-sciences-springer-dordrecht-2015-910-pp-349-00-isbn-978-94-017-9014-7
#13
https://www.readbyqxmd.com/read/27695996/hopf-bifurcations-in-directed-acyclic-networks-of-linearly-coupled-hindmarsh-rose-systems
#14
N Corson, V Lanza, N Verdière
This paper addresses the existence of Hopf bifurcations in a directed acyclic network of neurons, each of them being modeled by a Hindmarsh-Rose (HR) neuronal model. The bifurcation parameter is the small parameter corresponding to the ratio of time scales between the fast and the slow dynamics. We first prove that, under certain hypotheses, the single uncoupled neuron can undergo a Hopf bifurcation. Hopf bifurcation occurrences in a directed acyclic network of HR neurons are then discussed. Numerical simulations are carried out to observe these bifurcations and to illustrate the theoretical results...
October 3, 2016: Acta Biotheoretica
https://www.readbyqxmd.com/read/27592342/the-poitiers-school-of-mathematical-and-theoretical-biology-besson-gavaudan-sch%C3%A3-tzenberger-s-conjectures-on-genetic-code-and-rna-structures
#15
J Demongeot, H Hazgui
The French school of theoretical biology has been mainly initiated in Poitiers during the sixties by scientists like J. Besson, G. Bouligand, P. Gavaudan, M. P. Schützenberger and R. Thom, launching many new research domains on the fractal dimension, the combinatorial properties of the genetic code and related amino-acids as well as on the genetic regulation of the biological processes. Presently, the biological science knows that RNA molecules are often involved in the regulation of complex genetic networks as effectors, e...
September 3, 2016: Acta Biotheoretica
https://www.readbyqxmd.com/read/27485949/properties-of-life-toward-a-coherent-understanding-of-the-organism
#16
Bernd Rosslenbroich
The question of specific properties of life compared to nonliving things accompanied biology throughout its history. At times this question generated major controversies with largely diverging opinions. Basically, mechanistic thinkers, who tried to understand organismic functions in terms of nonliving machines, were opposed by those who tried to describe specific properties or even special forces being active within living entities. As this question included the human body, these controversies always have been of special relevance to our self-image and also touched practical issues of medicine...
September 2016: Acta Biotheoretica
https://www.readbyqxmd.com/read/27457070/functions-organization-and-etiology-a-reply-to-artiga-and-martinez
#17
Matteo Mossio, Cristian Saborido
We reply to Artiga and Martinez's claim according to which the organizational account of cross-generation functions implies a backward looking interpretation of etiology, just as standard etiological theories of function do. We argue that Artiga and Martinez's claim stems from a fundamental misunderstanding about the notion of "closure", on which the organizational account relies. In particular, they incorrectly assume that the system, which is relevant for ascribing cross-generation organizational function, is the lineage...
September 2016: Acta Biotheoretica
https://www.readbyqxmd.com/read/27364751/from-correlation-to-causation-what-do-we-need-in-the-historical-sciences
#18
Malte C Ebach, Michaelis S Michael
Changes in the methodology of the historical sciences make them more vulnerable to unjustifiable speculations being passed off as scientific results. The integrity of historical science is in peril due the way speculative and often unexamined causal assumptions are being used to generate data and underpin the identification of correlations in such data. A step toward a solution is to distinguish between plausible and speculative assumptions that facilitate the inference from measured and observed data to causal claims...
September 2016: Acta Biotheoretica
https://www.readbyqxmd.com/read/27283400/smt-and-toft-why-and-how-they-are-opposite-and-incompatible-paradigms
#19
Mariano Bizzarri, Alessandra Cucina
The Somatic Mutation Theory (SMT) has been challenged on its fundamentals by the Tissue Organization Field Theory of Carcinogenesis (TOFT). However, a recent publication has questioned whether TOFT could be a valid alternative theory of carcinogenesis to that presented by SMT. Herein we critically review arguments supporting the irreducible opposition between the two theoretical approaches by highlighting differences regarding the philosophical, methodological and experimental approaches on which they respectively rely...
September 2016: Acta Biotheoretica
https://www.readbyqxmd.com/read/27535677/smt-and-toft-integrable-after-all-a-reply-to-bizzarri-and-cucina
#20
Baptiste Bedessem, Stphanie Ruphy
In a previous paper recently published in this journal, we argue that the two main theories of carcinogenesis (SMT and TOFT) should be considered as compatible, at the metaphysical, epistemological and biological levels. In a reply to our contribution, Bizzarri and Cucina claim we are wrong since SMT and TOFT are opposite and incompatible paradigms. Here, we show that their arguments are not satisfactory. Indeed, the authors go through the same mistakes that we already addressed. In particular, they confuse reductionism, as an ontological frame, and genetic determinism, as a causal pathway...
August 17, 2016: Acta Biotheoretica
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