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Panminerva Medica

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https://www.readbyqxmd.com/read/29332376/new-and-emerging-treatments-for-metastatic-merkel-cell-carcinoma
#1
Giovanni Cestaro, Gennaro Quarto, Marco DE Monti, Fabrizio Fasolini, Marco DE Fazio, Ermenegildo Furino, Maurizio Gentile
No abstract text is available yet for this article.
January 11, 2018: Panminerva Medica
https://www.readbyqxmd.com/read/29164842/tumor-suppressor-role-of-mir-503
#2
Gaurav Gupta, Dinesh K Chellappan, Terezinha de Jesus Andreoli Pinto, Philip M Hansbro, Mary Bebawy, Kamal Dua
MicroRNAs (miRNAs) are noncoding RNAs of around 20-25 nucleotides in length with highly conserved characteristics. They moderate posttranscriptional silencing by precisely combining with 3' untranslated regions (UTRs) of target mRNAs at a complementary site. miR503, an associate of the "canonical" miRNA16 family, is expressed in numerous types of tumors such as breast cancer, prostate cancer, lung cancer, colorectal cancer, hepatocellular carcinoma, glioblastoma and several others. There is convincing evidence to show that miR503 functions as a tumor suppressor gene through its effects on target genes that regulate cell proliferation, migration, and invasion in tumor cells...
November 22, 2017: Panminerva Medica
https://www.readbyqxmd.com/read/29164841/home-blood-pressure-measurement-as-a-systematic-tool-for-clinical-practice-in-ckd-patients-a-real-world-picture
#3
Adamasco Cupisti, Lorenzo Ghiadoni, Claudia Zullo, Michele Marchini, Enrico Varricchio, Alessandro Puntoni, Elisabetta Giglio, Ophelia Meniconi, Maria R Bruno, Maria F Egidi
BACKGROUND: Arterial hypertension is very common in chronic kidney disease (CKD) patients and its prevalence increases with lowering estimated glomerular filtration rate (eGFR). Blood pressure (BP) control is a cornerstone in the treatment of CKD patients but still most treatment decisions are based on office BP measurement (OBPM). The aim of this cross-sectional, retrospective study is to investigate the prevalence of hypertension phenotypes in CKD patients and whether different home (HBPM) or OBPM are associated with a different CKD stage and cardiovascular comorbidities...
November 22, 2017: Panminerva Medica
https://www.readbyqxmd.com/read/29130298/role-of-micrornas-mirnas-in-pathophysiology-of-diabetes-mellitus
#4
Juhi Tiwari, Gaurav Gupta, Terezinha de Jesus Andreoli Pinto, Rahul Sharma, Kavita Pabreja, Yogesh Matta, Neha Arora, Anurag Mishra, Rakesh Sharma, Kamal Dua
Diabetes Mellitus is becoming the critical problem among the entire world and it is difficult to understand the molecular mechanism representing the concept of diabetic pathology. Recently the knowledge of the involvement of genetics in type 2 diabetes mellitus (T2DM) susceptibility has sketched a great concentration towards the transcriptional activity of ß cells within the pancreas. This disease becomes the leading cause of death so it is necessary to study the molecular pathogenesis, phenotypes, and characteristics to design the therapeutic parameters...
November 10, 2017: Panminerva Medica
https://www.readbyqxmd.com/read/29144072/relapse-and-cytogenetic-evolution-in-myeloid-neoplasms
#5
Natalie Ertz-Archambault, Katalin Kelemen
Based on the current WHO Classification of Myeloid Neoplasms, cytogenetic findings play a central role in the diagnostic classification of the myeloid malignancies. Cytogenetic abnormalities detected at primary diagnosis may change over time. Karyotype changes can be characterized as cytogenetic evolution, cytogenetic regression or a combination of both. While the exact mechanism of cytogenetic evolution is not completely understood, the process of cytogenetic evolution is not random, but follows different, and often disease-specific patterns during progression and relapse of myeloid neoplasms...
December 2017: Panminerva Medica
https://www.readbyqxmd.com/read/28650134/risk-of-hepatocellular-carcinoma-in-hbv-cirrhotic-patients-assessed-by-the-combination-of-mir-122-afp-and-pivka-ii
#6
Gian P Caviglia, Maria L Abate, Silvia Gaia, Elisa Petrini, Caterina Bosco, Antonella Olivero, Chiara Rosso, Alessia Ciancio, Rinaldo Pellicano, Giorgio M Saracco, Mario Rizzetto, Antonina Smedile
BACKGROUND: Reliable biomarkers for early detection of hepatocellular carcinoma (HCC) in patients with cirrhosis are lacking. We evaluated the use of miR-122, alpha-fetoprotein (AFP) and protein induced by vitamin k absence/antagonist II (PIVKA-II) for HCC risk prediction in patients with HBV-related cirrhosis under surveillance. METHODS: We first analyzed a group of 63 patients with HBV-related liver cirrhosis of whom 33 had HCC. Then we performed a retrospective analysis on another group of 13 cirrhotic patients who developed HCC during surveillance, of whom serial serum samples were available (at time of HCC diagnosis [T0], 6-9 months [T-1] and 12-18 months [T-2] before HCC detection)...
December 2017: Panminerva Medica
https://www.readbyqxmd.com/read/28994565/research-on-the-correlation-between-mmp-gene-polymorphism-and-susceptibility-to-cervical-cancer-in-chinese-women
#7
Lijuan Chen, Ping Qiang, Yang Shao
No abstract text is available yet for this article.
October 9, 2017: Panminerva Medica
https://www.readbyqxmd.com/read/28884567/high-peak-pao2-values-are-associated-with-adverse-outcome-in-critically-ill-patients-treated-with-non-invasive-ventilation-for-acute-cardogenic-pulmonary-edema-and-pneumonia
#8
Christiana Schernthaner, Bernhard Wernly, Michael Lichtenauer, Marcus Franz, Alexander Lauten, Paul C Schulze, Bjoern Kabisch, Kristina Braun, Johanna Muessig, Maryna Masyuk, Uta C Hoppe, Malte Kelm, Christian Jung
BACKGROUND: Non-invasive Ventilation (NIV) has a sigificant impact on mortality in acute respiratory failure (ARF). Predictive parameters for mortality are of high interest. METHODS: We retrospectively analyzed 3759 blood gas analysis and clinical parameters of 475 patients presenting with ARF based on acute cardiogenic pulmonary edema and/or pneumonia. The influence of peak arterial oxygen partial pressure levels (PaO2) with respect to its predictive value for in-hopital and long-term mortality was investigated...
September 7, 2017: Panminerva Medica
https://www.readbyqxmd.com/read/28884566/effects-on-cognitive-function-of-propofol-medium-and-long-chain-lipid-emulsion-in-patients-with-hepatic-encephalopathy
#9
Shenghui Yu, Jianlei Hu, Li Ding, Da Yu
BACKGROUND: Our study aimed to investigate the effects of propofol medium and long chain lipid emulsion on cognitive function of the patients with hepatic encephalopathy undergoing hemofiltration treatment. METHODS: A total of 87 patients diagnosed with hepatic encephalopathy from January 2014 to January 2016 were continuously selected, and randomly (Using Random number method) divided into an observation group (45 cases) and a control group (42 cases). All patients were treated with persistent hemofiltration; the patients in control group were not given any sedative measures, while the patients in observation group were given a propofol medium-long chain lipid emulsion injection with a dose determined by each individual's degree of restlessness and tolerance to hemofiltration (Intravenous injection was performed with the first dose of 100mg, and then patients are subjected to micro-infusion pump with a dose of 0...
September 7, 2017: Panminerva Medica
https://www.readbyqxmd.com/read/28880054/effects-of-family-centered-care-based-on-timing-it-right-on-the-care-ability-and-the-quality-of-life-of-family-members-of-patients-with-acute-myocardial-infarction
#10
Mingxing Xu, Dongfeng Han, Xiaolei Wang, Xiaoxiang Yu, Weilin Hao, Dongmei Zhu
No abstract text is available yet for this article.
September 5, 2017: Panminerva Medica
https://www.readbyqxmd.com/read/28880053/liver-fibrosis-the-2017-state-of-art
#11
Gian P Caviglia, Chiara Rosso, Sharmila Fagoonee, Giorgio M Saracco, Rinaldo Pellicano
Liver fibrosis is a wound-healing response to a wide spectrum of chronic liver injuries. It is characterized by loss of hepatocytes and alteration in hepatic architecture following an imbalance between extracellular matrix synthesis and degradation. Irrespectively of underlying etiology, fibrosis may progress to cirrhosis and specific pathogenetic mechanisms as well as different disease patterns may be identified according to etiology. Liver biopsy is still considered the gold standard for fibrosis assessment, despite the fact that it is invasive, has poor patient compliance and is not exempt of complications...
September 5, 2017: Panminerva Medica
https://www.readbyqxmd.com/read/28665101/uca1-lncrna-in-metastases-and-prognosis
#12
Wei Song, Kai Wang, Shu-Bing Zou
No abstract text is available yet for this article.
September 2017: Panminerva Medica
https://www.readbyqxmd.com/read/28665100/nanotechnology-potential-tool-for-immunology
#13
Bilal Aslam, Muhammad A Nisar, Mohsin Khurshid, Saima Muzammil, Sumreen Hayat
No abstract text is available yet for this article.
September 2017: Panminerva Medica
https://www.readbyqxmd.com/read/28665099/improvement-in-behavioral-and-psychological-symptoms-of-dementia-by-rivastigmine-patch-in-a-group-of-italian-elderly-patients-with-alzheimer-s-disease
#14
Adriana Servello, Evaristo Ettorre, Mauro Cacciafesta
No abstract text is available yet for this article.
September 2017: Panminerva Medica
https://www.readbyqxmd.com/read/28665098/food-supplements-stress-and-gastrointestinal-diseases
#15
Davide G Ribaldone, Giorgio M Saracco
No abstract text is available yet for this article.
September 2017: Panminerva Medica
https://www.readbyqxmd.com/read/28665097/how-to-interpret-meta-analysis-results
#16
Davide G Ribaldone, Elisa Petrini
No abstract text is available yet for this article.
September 2017: Panminerva Medica
https://www.readbyqxmd.com/read/28488841/catastrophic-antiphospholipid-syndrome-an-update
#17
Gerard Espinosa, Ignasi Rodríguez-Pintó, Ricard Cervera
Catastrophic antiphospholipid syndrome (CAPS) is a rare variant that accounts for 1% of patients with APS. Despite its low frequency, the mortality-related is very high ranging from 50% of patients in the first series to 37% in the most recent data. The current knowledge of this potential devastating entity comes from the International Registry of patients with CAPS, named CAPS Registry. Small vessel thrombosis, laboratory features of microangiopathic haemolytic anemia, and development of multisystem involvement in a very short period of time are the main characteristics of this syndrome...
September 2017: Panminerva Medica
https://www.readbyqxmd.com/read/28752986/analysis-of-medium-long-term-therapeutic-effect-of-pcm-artificial-cervical-disc-replacement
#18
Haibo Li, Yiping Weng, Dong Zhou, Luming Nong, Nanwei Xu
No abstract text is available yet for this article.
July 28, 2017: Panminerva Medica
https://www.readbyqxmd.com/read/28714299/new-serum-markers-for-detection-of-early-hepatocellular-carcinoma
#19
Ludovico Abenavoli, Luigi Boccuto
No abstract text is available yet for this article.
July 13, 2017: Panminerva Medica
https://www.readbyqxmd.com/read/28290189/helicobacter-pylori-2017-revitalized-therapies-for-an-ever-challenging-bug
#20
Giovanni C Actis
No abstract text is available yet for this article.
June 2017: Panminerva Medica
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