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Acta Medica Okayama

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https://www.readbyqxmd.com/read/29276230/disseminated-nontuberculous-mycobacterial-infection-in-a-patient-with-anti-ifn-%C3%AE-autoantibodies
#1
Masakuni Tanimizu, Kenji Mizuno, Masayuki Hashimoto
We treated a 72-year-old Japanese female with sustained high fever and overall body exhaustion. An infectious liver cyst and right lung pneumonia were suspected causes. Hepatic cystectomy and various antibiotics did not resolve symptoms. Pneumonia exacerbation and ascitic fluid retention, left lumbar spinal osteomyelitis, and peri-gastric lymph node abscess penetrating the stomach were observed. Mycobacterium avium was identified in sputum, ascites, vertebral body abscess puncture specimen, and pus mucus secretion in the stomach...
December 2017: Acta Medica Okayama
https://www.readbyqxmd.com/read/29276229/severe-acute-respiratory-distress-syndrome-using-electrical-activity-of-the-diaphragm-on-weaning-from-extracorporeal-membrane-oxygenation
#2
Shuji Okahara, Kazuyoshi Shimizu, Hiroshi Morimatsu
The electrical activity of the diaphragm (EAdi) shows global diaphragmatic activation and power output from the central nervous system. We measured the EAdi as an indicator of breathing workload in a 40-year-old man suffering from severe acute respiratory distress syndrome (ARDS) secondary to influenza pneumonia in the process of weaning from extracorporeal membrane oxygenation (ECMO). Turning off the sweep gas flow immediately led to EAdi elevation, followed by hypoxia. The patient was successfully weaned from ECMO by reference to EAdi...
December 2017: Acta Medica Okayama
https://www.readbyqxmd.com/read/29276228/retinal-nerve-fiber-layer-defect-and-paracentral-scotoma-after-internal-limiting-membrane-peeling-with-a-nitinol-loop
#3
Ryo Matoba, Yuki Morizane, Shuhei Kimura, Shinji Toshima, Fumio Shiraga
Internal limiting membrane (ILM) peeling is an important maneuver in vitrectomy for macular holes (MHs). A nitinol loop is a surgical instrument designed to create an edge on the ILM and peel the ILM safely and consistently. The effect of using a nitinol loop for ILM peeling on the retina is not clear. We report here on a case of an idiopathic full-thickness MH in an adult woman, in whom retinal damage was revealed after her ILM was peeled using a nitinol loop.
December 2017: Acta Medica Okayama
https://www.readbyqxmd.com/read/29276227/constant-current-vs-constant-voltage-systems-for-temporal-spinal-cord-stimulation-for-intractable-pain
#4
Mayu Ooi, Fujio Yanamoto, Hitoaki Sato, Yumiko Takao, Masako Okada, Moritoki Egi, Satoshi Mizobuchi
Although spinal cord stimulation (SCS) is a useful treatment for chronic intractable pain, the optimal method of stimulation has not yet been established. In this prospective, crossover study, we compared the efficacy of using a constant current (CC) system with that of a constant voltage (CV) system for temporal SCS. Twenty patients were enrolled and divided into two groups. For 10 patients, a CV system was applied on Days 1-5, followed by the use of a CC system on Days 6-10. For the other 10 patients, a CC system was applied for the first five days, followed by a CV system for the subsequent five days...
December 2017: Acta Medica Okayama
https://www.readbyqxmd.com/read/29276226/relationship-between-the-axillary-nerve-and-accompanying-vessels-and-proximal-humeral-locking-plates-in-japanese-an-mri-study
#5
Yoshimasa Sakoma, Takahiko Hirooka
We investigated the anatomical features of the axillary nerve and its accompanying vessels with respect to the lateral wall of the greater tuberosity, focusing on the relationship between the neurovascular bundle and the proximal humeral locking plates. Magnetic resonance images of 30 Japanese patients' shoulders were examined. Oblique sagittal images across the greater tuberosity and the neurovascular bundle, which contain the axillary nerve and posterior circumflex humeral artery and vein, were obtained. The distance between the superior aspect of the greater tuberosity and the superior and inferior borders of the neurovascular bundles was measured at the anterior, middle, and posterior edges of the greater tuberosity...
December 2017: Acta Medica Okayama
https://www.readbyqxmd.com/read/29276225/the-incidence-of-oral-and-oropharyngeal-cancers-in-betel-quid-chewing-populations-in-south-myanmar-rural-areas
#6
Nobuyoshi Mizukawa, Swe Swe Win, Zaw Moe Thein, Moe Thida Htwe, Yohsuke Yoshioka, Yoshihiro Kimata, Seiji Iida, Myo Khin, Shigeru Okada, Than Sein
Oral cancer is a very common disease in South and Southeast Asia. Betel quid (BQ)- chewing and tobaccosmoking habits are etiological factors for oral cancer patients in these regions. We conducted an oral cancer screening in BQ-chewing endemic rural areas in South Myanmar for the early detection of oral cancer in BQ-chewing and smoking individuals. We examined 105 subjects who were at high risk of oral cancer due to their oral habits (BQ users and/or smokers). Three carcinoma cases were detected, and there were 8 dysplasia cases...
December 2017: Acta Medica Okayama
https://www.readbyqxmd.com/read/29276224/feasibility-trial-of-oral-uft-after-platinum-based-adjuvant-chemotherapy-in-patients-with-resected-non-small-cell-lung-cancer
#7
Shigeki Sawada, Ryujiro Sugimoto, Tsuyoshi Ueno, Motohiro Yamashita
We evaluated the feasibility of maintenance treatment using UFT (a combination of tegafur and uracil) after adjuvant platinum-based chemotherapy in patients with resected lung cancer. A prospective feasibility trial was conducted. Between 2010 and 2014, UFT was administered for 2 years sequentially after platinum-based adjuvant chemotherapy in 24 patients with resected Stage IIA-IIIA non-small cell lung cancer. The safety of UFT and the rate of treatment completion were then evaluated. The prior platinum-based chemotherapy regimens consisted of cisplatin+vinorelbine in 16 patients, carboplatin+paclitaxel in 5 and carboplatin+S-1 in one...
December 2017: Acta Medica Okayama
https://www.readbyqxmd.com/read/29276223/effects-of-epigallocatechin-3-gallate-on-egfr-or-fusion-gene-driven-lung-cancer-cells
#8
Yoshihiro Honda, Nagio Takigawa, Eiki Ichihara, Takashi Ninomiya, Toshio Kubo, Nobuaki Ochi, Masayuki Yasugi, Toshi Murakami, Hiromichi Yamane, Mitsune Tanimoto, Katsuyuki Kiura
No abstract text is available yet for this article.
December 2017: Acta Medica Okayama
https://www.readbyqxmd.com/read/29276222/lavender-essential-oil-and-its-main-constituents-inhibit-the-expression-of-tnf-%C3%AE-induced-cell-adhesion-molecules-in-endothelial-cells
#9
Michinori Aoe, Tomoe Ueno-Iio, Misako Shibakura, Ryoko Shinohata, Shinichi Usui, Yujiro Arao, Satoru Ikeda, Nobuaki Miyahara, Mitsune Tanimoto, Mikio Kataoka
Lavender essential oil (Lvn) has anti-inflammatory effects in an ovalbumin-sensitized murine model of asthma, and inhibits inflammatory cell infiltration into the lungs. The anti-inflammatory effects of Lvn on cell adhesion molecules are not clear. Here we evaluated the effects of Lvn and its main constituents, linalyl acetate (LA) and linalool (LO), on the expression of tumor necrosis factor-alpha (TNF-α)-induced cell adhesion molecules in murine brain endothelial bEnd.3 cells and human umbilical vein endothelial cells (HUVECs)...
December 2017: Acta Medica Okayama
https://www.readbyqxmd.com/read/29276221/effects-of-postprandial-body-position-on-gastrointestinal-motility-the-autonomic-nervous-system-and-subjective-comfort
#10
Ayaka Okano, Shun Masuhara, Sonoka Ota, Chie Motegi, Noriko Takabayashi, Tetsuya Ogino
We examined postprandial body positions' effects on gastrointestinal motility, the autonomic nervous system and subjective comfort, i.e., whether lowering the head after a meal is beneficial for gastrointestinal motility and the prevention of pressure ulcer. We examined 10 healthy subjects and compared 3 body positions: (1) Seated upright. (2) Lying on a bed with the head at 60° and knees up by 20° (60° position). (3) Identical to (2) until post-meal; the head was then lowered to 30° (60°-30° position)...
December 2017: Acta Medica Okayama
https://www.readbyqxmd.com/read/29276220/metachronous-neoplasia-and-local-recurrence-after-colorectal-endoscopic-submucosal-dissection
#11
Daisuke Takei, Keita Harada, Shiho Takashima, Toshihiro Inokuchi, Asuka Nakarai, Yusaku Sugihara, Masanobu Takahara, Sakiko Hiraoka, Hiroyuki Okada
Several reports discussed colonoscopic surveillance after polypectomy and endoscopic mucosal resection (EMR) for colorectal polyps, but only a few reports focused on prognostic analyses, and none involved metachronous neoplasia after colorectal endoscopic submucosal dissection (ESD). We conducted the present study to assess the risk of adenoma recurrence requiring endoscopic treatment, and to establish appropriate post-ESD colonoscopic surveillance. We enrolled 116 patients who had undergone colorectal ESD at Okayama University Hospital between February 2008 and July 2014 and had been followed-up >12 months...
December 2017: Acta Medica Okayama
https://www.readbyqxmd.com/read/29276219/indirect-calorimetry-measurement-of-energy-expenditure-related-to-body-position-changes-in-healthy-adults
#12
Kengo Obata, Tetsuya Yumoto, Soichiro Fuke, Kohei Tsukahara, Hiromichi Naito, Atsuyoshi Iida, Tetsuya Takahashi, Yoshihito Ujike, Atsunori Nakao
Early mobilization is advocated to prevent intensive care unit-acquired physical weakness, but the patient's workload and its changes in response to body position changes have not been established. We used indirect calorimetry to determine the energy expenditure (EE) in response to body position changes, and we assessed EE's correlation with respiratory parameters in healthy volunteers: 8 males and 8 females, mean age 23.4±1.3 years. The subjects started in the resting supine position followed by a 30° head-up position, a 60° head-up position, an upright sitting position, a standing position, and the resting supine position...
December 2017: Acta Medica Okayama
https://www.readbyqxmd.com/read/29276218/signal-diversity-of-receptor-for-advanced-glycation-end-products
#13
REVIEW
Masakiyo Sakaguchi, Rie Kinoshita, Endy Widya Putranto, I Made Winarsa Ruma, I Wayan Sumardika, Chen Youyi, Naoko Tomonobu, Ken-Ichi Yamamoto, Hitoshi Murata
The receptor for advanced glycation end products (RAGE) is involved in inflammatory pathogenesis. It functions as a receptor to multiple ligands such as AGEs, HMGB1 and S100 proteins, activating multiple intracellular signaling pathways with each ligand binding. The molecular events by which ligand-activated RAGE controls diverse signaling are not well understood, but some progress was made recently. Accumulating evidence revealed that RAGE has multiple binding partners within the cytoplasm and on the plasma membrane...
December 2017: Acta Medica Okayama
https://www.readbyqxmd.com/read/29042706/protective-effects-of-bisoprolol-against-acute-exacerbation-in-moderate-to-severe-chronic-obstructive-pulmonary-disease
#14
Akihiko Taniguchi, Nobuaki Miyahara, Naohiro Oda, Daisuke Morichika, Eiki Ichihara, Isao Oze, Yasushi Tanimoto, Hirohisa Ichikawa, Utako Fujii, Mitsune Tanimoto, Arihiko Kanehiro, Katsuyuki Kiura
Although recent retrospective studies suggested that the use of β-blockers appears to help improve the mortality rate and decrease the rate of exacerbation in chronic obstructive pulmonary disease (COPD) patients with heart failure, the effects of β-blockers on COPD patients without heart failure have not been established. Based on previous reports, we have launched a multicenter, prospective, single-arm phase II study to evaluate the preventive effect of the cardioselective β-blocker bisoprolol in COPD exacerbation, in Japanese individuals with moderate-to-severe COPD who do not have heart failure but do have hypertension requiring the use of medication...
October 2017: Acta Medica Okayama
https://www.readbyqxmd.com/read/29042705/ureterolithotripsy-for-a-ureteral-calculus-at-the-ureteroureterostomy-of-a-renal-transplant-recipient
#15
Yosuke Mitsui, Koichiro Wada, Motoo Araki, Takashi Yoshioka, Yuichi Ariyoshi, Shingo Nishimura, Yasuyuki Kobayashi, Katsumi Sasaki, Toyohiko Watanabe, Yasutomo Nasu
We describe a 40-year-old living-donor renal-transplant recipient who underwent successful ureterolithotripsy. He had been on hemodialysis for >15 years pre-transplant and underwent ureteroureterostomy along with the surgery. One year post-transplant, ultrasound examination demonstrated hydronephrosis, and CT showed a 6-mm ureteral calculus at the ureteroureterostomy site. No pain and no elevated serum creatinine were present. As the ureter was easily accessed, we performed a ureterolithotripsy, which would confirm whether a suture caused the calculus...
October 2017: Acta Medica Okayama
https://www.readbyqxmd.com/read/29042704/alternative-to-rituximab-therapy-for-a-patient-with-ankylosing-spondylitis-who-was-unable-to-continue-anti-tnf-therapy
#16
Eri Katsuyama, Hiroshi Wakabayashi, Ken-Ei Sada, Sumie Hiramatsu, Yoshia Miyawaki, Michiko Morishita, Keiji Ohashi, Haruki Watanabe, Takayuki Katsuyama, Sonia Zeggar, Mariko Narazaki, Noriko Tatebe, Katsue Sunahori-Watanabe, Tomoko Kawabata, Jun Wada
We herein present a case of a 38-year-old man who had bamboo spine and severe sacroiliitis and who was diagnosed with ankylosing spondylitis (AS). Infliximab (IFX) markedly improved the axial symptom but was discontinued due to the side effect of peripheral neuropathy. Switching from IFX to etanercept worsened the side effect. Rituximab (RTX) administration elicited a good response without side effects. RTX might be a suitable option for AS therapy when TNF inhibitors are difficult to use.
October 2017: Acta Medica Okayama
https://www.readbyqxmd.com/read/29042703/modification-of-dentofacial-growth-associated-with-goldenhar-syndrome
#17
Ei Ei Hsu Hlaing, Yoshihito Ishihara, Chikako Hara, Hiroshi Kamioka
The rare developmental defect, Goldenhar syndrome is characterized by complex craniofacial and dentofacial anomalies. Here we describe the successful orthodontic treatment of a 5-year-old Japanese Goldenhar syndrome patient with mild facial asymmetry, right microtia, right-side hearing loss, and tongue-thrusting by a modification of dentofacial growth using a non-surgical orthopedic treatment approach. Improvement of the vertical discrepancies on the affected side and canted occlusal plane as well as mandibular deviation were achieved with a functional orthopaedic approach...
October 2017: Acta Medica Okayama
https://www.readbyqxmd.com/read/29042702/genetic-factors-of-low-responsiveness-to-hepatitis-b-virus-vaccine-confirms-the-importance-of-human-leukocyte-antigen-class-ii-types-in-a-japanese-young-adult-population
#18
Nobuyasu Yukimasa, Shota Kohama, Wataru Oboshi, Shoichi Sato, Takehiro Nakamura
We investigated the genetic mechanisms underlying the association between human leukocyte antigen (HLA) types and the immune response to hepatitis B virus (HBV) vaccination in 84 healthy Japanese adults, and found that the HLA-DRB1*04 and HLA-DQB1*03 frequencies were higher in the low responders (<10 mIU/ml; n=9, 10.7%) compared to the responders (≥10 mIU/ml, n=75, 89.3%). The combination of DRB1*04 and DQB1*03 was associated with a low response to vaccination. The DRB1*04 and DQB1*03 haplotypes' frequencies were significantly higher in the low responders compared to responders...
October 2017: Acta Medica Okayama
https://www.readbyqxmd.com/read/29042701/direct-damage-to-a-vertebral-artery-better-predicts-a-vertebral-artery-injury-than-elongation-in-cervical-spine-dislocation
#19
Kosei Nagata, Hirotaka Chikuda, Koichi Inokuchi, Keisuke Ishii, Atsuki Kobayashi, Hiroyuki Kanai, Kota Miyoshi
Cervical spine dislocation and fracture of a transverse process are isolated risk factors for vertebral artery injuries (VAIs), which can cause a life-threatening ischemic stroke. Since in vivo experiments are not possible, it has not been unclear whether damage to or extension of vertebral arteries is more predictive of a VAI. To identify the imaging characteristics associated with VAI, we analyzed 36 vertebral arteries from 22 cervical spine dislocation patients who underwent computed tomography angiography (Aug...
October 2017: Acta Medica Okayama
https://www.readbyqxmd.com/read/29042700/preoperative-risk-factors-for-conversion-of-laparoscopic-cholecystectomy-to-open-cholecystectomy-and-the-usefulness-of-the-2013-tokyo-guidelines
#20
Masashi Utsumi, Hideki Aoki, Tomoyoshi Kunitomo, Yutaka Mushiake, Isao Yasuhara, Fumitaka Taniguchi, Takashi Arata, Koh Katsuda, Kohji Tanakaya, Hitoshi Takeuchi
To identify predictive factors for conversion from laparoscopic cholecystectomy (LC) to open cholecystectomy performed for mixed indications as an acute or elective procedure. We retrospectively analyzed the data of 236 consecutive cases of LC performed in our department between January 2012 and January 2015, and evaluated preoperative risk factors for conversion and the usefulness of the 2013 Tokyo guidelines (TG2013) for diagnosing acute cholecystitis. The conversion rate in our series was 8% (19/236 cases)...
October 2017: Acta Medica Okayama
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