İrem Eldem, Tanıl Kendirli, Ebru Azapağası, Gülşah Özdemir, Çisem Yıldız, Mehmet Mustafa Yılmaz, Özlem Karataşoğlu, Elif Benderlioğlu
Venlafaxine is a selective serotonin noradrenaline reuptake inhibitor and commonly prescribed antidepressant in adults. Most patients overdosing with venlafaxine develop only mild symptoms. Severe toxicity is reported with the most common symptoms being CNS depression, serotonin toxicity, seizure, or cardiac conduction abnormalities. However, lactic acidosis is an uncommon adverse effect. Here, we present the first case in the literature reporting lactic acidosis due to venlafaxine overuse in an adolescent.
2016: Turkish Journal of Pediatrics