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Indian Journal of Pediatrics

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https://www.readbyqxmd.com/read/29218646/cardiovascular-and-metabolic-complications-diagnosis-and-management-in-obese-children
#1
REVIEW
Naval K Vikram
The world at present is facing a burden of rising prevalence of obesity in children and adolescents. The developing countries are particularly facing the dual burden on under-nutrition and obesity. This is associated with appearance and clustering of cardiometabolic abnormalities at an early age with development of chronic complications early and possible decrease in life span of these children and adolescents. In adults this clustering has been termed as 'metabolic syndrome' with definitions that can be used universally...
December 8, 2017: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/29185231/translating-asthma-dissecting-the-role-of-metabolomics-genomics-and-personalized-medicine
#2
Andrew Bush
The management of asthma has largely stagnated over the last 25 years, but we are at the dawning of a new age wherein -omics technology can help us manage the disease objectively and rationally. Even in this new scientific age, getting the basics of asthma management right remains essential. The new technologies which can be applied to multiple biological samples include genomics (study of the genome), transcriptomics (gene transcription), lipidomics, proteomics and metabolomics (lipids, proteins and metabolites, respectively) and breathomics, using exhaled breath as a source of biomarkers, which is of particular interest in view of its non-invasive nature in pediatrics...
November 29, 2017: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/29185230/molecular-epidemiology-of-rotavirus-strains-in-under-five-children
#3
Yunus Bulut, Gülgün Yenişehirli, Rıza Durmaz
OBJECTIVES: To determine the prevalence and genotype distribution of rotaviruses in children presenting to authors' hospital in Middle Black Sea region of Turkey. The results may supply important information about vaccine studies in Turkey. METHODS: Rotavirus antigen was detected by latex agglutination test and rotavirus RNA was detected by RT-PCR test. On the other hand, rotavirus positive samples were genotyped by semi-nested multiplex polymerase chain reaction...
November 29, 2017: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/29177811/genetic-and-syndromic-causes-of-obesity-and-its-management
#4
REVIEW
Ildiko H Koves, Christian Roth
The aim of this article is to provide an in depth review of the rare genetic and syndromic forms of childhood obesity. The authors demonstrate the complexity and inter-relationships of the leptin-melanocortin signaling pathway and its central nervous system and systemic effects. Authors highlight the clinical distinctive features of genetic/syndromic causes for childhood obesity, in particular, relative shorter height to their genetic potential, developmental challenges and in some instances, ophthalmological and retina changes...
November 27, 2017: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/29177599/obesity-in-children-definition-etiology-and-approach
#5
REVIEW
Bhawana Aggarwal, Vandana Jain
Childhood obesity is an important public health issue worldwide. Urbanization, sedentary lifestyle and change in food habits are the chief reasons behind this pandemic. In a small proportion of children, obesity is the result of endocrine, syndromic or monogenic causes. The present paper summarizes the methods, definitions and cut-offs for identification of obesity in children. We have briefly reviewed the various techniques used for estimation of body fat in children and the cut-offs for defining obesity based on body fat percentage, and the reference curves based on body mass index and waist circumference...
November 25, 2017: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/29170924/frontotemporal-atrophy-presenting-sign-in-infantile-cobalamin-deficiency
#6
LETTER
Pallavi Vats, Prashant Verma, Bijo Varughese, Somesh Kumar, Seema Kapoor
No abstract text is available yet for this article.
November 23, 2017: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/29170923/urinary-screening-for-early-detection-of-kidney-diseases
#7
Kamlesh S Suthar, Aruna V Vanikar, Lovelesh A Nigam, Rashmi D Patel, Kamal V Kanodia, Umang G Thakkar, Paulin A Gandhi, Sheetal A Chandak, Amit V Prajapati, Minaxi H Patel
OBJECTIVE: Urinary screening is a simple inexpensive tool to evaluate kidney functions. The authors carried out urinary screening of school children for early detection of kidney diseases. METHODS: Children in the age group 5-15 y were screened for urinalysis. They were divided in 2 groups; group-1 included 5-10 y and group-2 included >10-15 y old children. RESULTS: Urine samples of 3340(78%) out of 4283 enrolled children were tested. Abnormal samples were found in 5...
November 23, 2017: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/29170922/vaccine-safety-and-surveillance-for-adverse-events-following-immunization-aefi-in-india
#8
Jyoti Joshi, Manoja Kumar Das, Deepak Polpakara, Satinder Aneja, Mahesh Agarwal, Narendra Kumar Arora
Assured quality vaccines and safe immunization practices are pre-requisite to successful immunization programs. All vaccines go through stringent safety checks during pre-licensure stage. Adverse Events Following Immunization (AEFI) Surveillance program is an integral part of routine immunization program in India to monitor the vaccine safety in the post licensure phase. Indian AEFI Program: National AEFI surveillance relies on passive surveillance and reporting by the health functionaries and practitioners...
November 23, 2017: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/29170921/unexplained-transaminitis-and-hyperactivity-do-not-forget-the-musculoskeletal-examination
#9
LETTER
Sumeet R Dhawan, Saniya Gupta, Lokesh Saini
No abstract text is available yet for this article.
November 23, 2017: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/29170920/dacrystic-epilepsy
#10
LETTER
Chandan Raybarman
No abstract text is available yet for this article.
November 23, 2017: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/29152688/serum-zinc-levels-as-a-predictor-of-severity-of-acute-diarrhea
#11
Astha Agarwal, Navratan Kumar Gupta, Amit Upadhyay, R K Soni, Dheeraj Shah, Vijay Jaiswal
OBJECTIVE: To determine relationship between serum zinc levels and severity of diarrhea as determined by hydration status, duration of diarrhea and requirement for hospitalization. Also, to compare serum zinc levels in relation to rotavirus status. METHODS: A prospective observational study which included 254 children aged 6 mo to 5 y with diarrhea was conducted. RESULTS: Serum zinc levels could be estimated in 198 children. Median (IQR) serum zinc levels of study population were 73...
November 20, 2017: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/29152687/utility-of-low-fidelity-manikins-for-learning-high-quality-chest-compressions
#12
Meenakshi Girish, Alka Rawekar, Sujo Jose, Umesh Chaudhari, Girish Nanoti
OBJECTIVES: Primarily, to measure the adequacy of chest compression depth after training on low fidelity manikins and secondarily to assess the comparative experience of the learners on high fidelity and low fidelity simulators. METHODS: An observational cohort study in which seventy-two first year postgraduate students underwent a Basic Life Support (BLS) workshop conducted by AHA accredited BLS trainers and they were then required to perform on a high fidelity manikin to objectively record the quality of their performance...
November 20, 2017: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/29152686/tetralogy-of-fallot-with-restrictive-ventricular-septal-defect
#13
LETTER
Ashish Tiwari, Savita Bhunwal, Manojkumar Rohit
No abstract text is available yet for this article.
November 20, 2017: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/29152685/cerebral-palsy-an-overview
#14
REVIEW
Sheffali Gulati, Vishal Sondhi
Cerebral palsy (CP) is a neurodevelopmental disorder characterized by abnormalities of muscle tone, movement and motor skills, and is attributed to injury to the developing brain. The clinical features of this entity evolve over time and the specific CP syndrome may be recognizable only after 3-5 y of age; although suggestive signs and symptoms may be present at an earlier age. The management involves neurological rehabilitation (addressing muscle tonal abnormalities, and devising physical and occupational therapies) and diagnosis and management of co-morbidities (including epilepsy, impairment of cognition, vision, hearing, and disturbances of growth and gastrointestinal function)...
November 20, 2017: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/29152684/infantile-systemic-lupus-erythematosus-with-cerebral-calcification-and-delayed-development
#15
LETTER
Taru Garg, Sarita Sanke, Ram Chander, Shilpi Agarwal, Riaz Ahmed
No abstract text is available yet for this article.
November 20, 2017: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/29152683/newer-development-in-immunization-practices
#16
EDITORIAL
A K Dutta, Anju Aggarwal
No abstract text is available yet for this article.
November 20, 2017: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/29150753/psychological-aspects-of-obesity-in-children-and-adolescents
#17
Rajesh Sagar, Tanu Gupta
Childhood obesity is multi factorial health condition, so the simple evaluation of body fat will not be sufficed to manage the global epidemic of childhood obesity. Literature consistently provides evidence for physical health risks associated with childhood obesity; however in recent times, mental health of the obese children has also gained attention of the researchers as well as clinicians. Obese children experience number of psycho-social problems that significantly affect their quality of life and wellbeing...
November 18, 2017: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/29147890/food-allergy-in-children-an-overview
#18
REVIEW
Jaidev M Devdas, Christopher Mckie, Adam T Fox, Vinod H Ratageri
The estimated prevalence of food allergy amongst children in the west is around 6-8% but there is paucity of data in the Indian population. There is a complex interplay of environmental influences and genetic factors in the immuno-pathogenesis and manifestations of food allergy. A reliable thorough clinical history, combined with positive skin prick tests or food-specific IgE, is essential for a more precise diagnosis of food allergy. Currently there is no cure for food allergy. The management of food allergy usually includes strict avoidance, patient education and provision of emergency medication (adrenaline-autoinjectors)...
November 17, 2017: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/29147889/association-of-il-10-gene-polymorphism-819c%C3%A2-%C3%A2-t-592c%C3%A2-%C3%A2-a-and-1082g%C3%A2-%C3%A2-a-with-preterm-birth
#19
Monika Pandey, Shally Awasthi, Urmila Singh, Abbas Ali Mahdi
OBJECTIVE: To analyze the association of IL-10 gene and its polymorphisms with preterm birth (PTB). METHODS: Five hundred and fifty nine women with term birth and 559 with preterm birth were recruited from Lucknow, India. Genetic association analysis was conducted between cases and controls. Subjects recruited as cases were women (aged between 18-40 y) with singleton delivery before 37 wk of gestation and controls were with delivery after or on 37 wk. The genotyping was performed for rs1800871, rs1800872 and rs1800896 for assessing the allelic distribution, haplotypic association and linkage disequilibrium analysis...
November 17, 2017: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/29143254/chronic-inflammatory-demyelinating-polyneuropathy-a-case-series
#20
LETTER
Arunmozhimaran Elavarasi, Vinay Goyal, Venugopalan Vishnu, Mamta Bhushan Singh, Padma Srivastava
No abstract text is available yet for this article.
November 16, 2017: Indian Journal of Pediatrics
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