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Urologia Internationalis

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https://www.readbyqxmd.com/read/28231570/analysis-of-a-surgical-treatment-for-persistent-urorectal-fistulas-after-radical-cancer-surgery-a-comparison-of-prostate-cancer-and-rectal-cancer
#1
Yasuyuki Sakai, Yoshinobu Komai, Norio Saito, Masaaki Ito, Minoru Sakuraba
INTRODUCTION: The study aimed to present our experience of surgical treatment for urorectal fistulas (URF) that develop after cancer surgery. MATERIALS AND METHODS: Fourteen patients with URF who were treated at our institution from 2005 through 2015 were retrospectively analyzed. Among these, 7 patients had previous surgical treatment of prostate cancer (PC) and the other 7 had been treated for rectal cancer (RC). The fistula was resected through a perineal incision, and the urinary and fecal defects were separately closed with the hinge flap method followed by interposition of a muscle flap transfer...
February 24, 2017: Urologia Internationalis
https://www.readbyqxmd.com/read/28222442/transvesical-suprapubic-externalization-of-ureteral-stents-introduction-of-a-surgical-innovation-at-the-development-stage
#2
Holger Gerullis, Klaus Schwartmann, Thorsten H Ecke, Evangelos Georgas, Philip Herberg, Alexander Winter, Friedhelm Wawroschek, Dimitri Barski, Thomas Otto
BACKGROUND AND OBJECTIVES: In this study, we describe our first experiences with the new method of transvesical suprapubic externalization of ureteral stents. This method is assessed in patients with incurable ureteral obstruction and concomitant bladder dysfunction, and is classified according to the Idea, Development, Exploration, Assessment, Long-Term Study (IDEAL) recommendations. PATIENTS AND METHODS: From 2009 to 2015, transvesical suprapubic externalization of ureteral stents was applied in 14 (8 males, 6 females) patients with incurable ureteral obstruction of malignant (n = 9, 64%) or benign (n = 5; 36%) etiology...
February 22, 2017: Urologia Internationalis
https://www.readbyqxmd.com/read/28222423/introduction-of-an-enhanced-recovery-after-surgery-protocol-for-robot-assisted-laparoscopic-radical-prostatectomy
#3
Motohiko Sugi, Tadashi Matsuda, Takashi Yoshida, Hisanori Taniguchi, Takao Mishima, Masaaki Yanishi, Yoshihiro Komai, Kaneki Yasuda, Hidefumi Kinoshita, Kenji Yoshida, Masato Watanabe
INTRODUCTION: No studies have shown whether the enhanced recovery after surgery (ERAS) protocol is superior to the conventional protocol after robot-assisted laparoscopic radical prostatectomy (RALP). We compared intestinal function and perioperative parameters of patients with prostate cancer after the ERAS and conventional protocols to determine the superior protocol for recovery of intestinal function. MATERIAL AND METHODS: A retrospective analysis of 198 consecutive patients who underwent RALP between August 2013 and June 2015 was conducted...
February 17, 2017: Urologia Internationalis
https://www.readbyqxmd.com/read/28196363/a-paratesticular-multicystic-tumor-of-the-tunica-vaginalis-testis-as-rare-paratesticular-cystadenoma
#4
Desiree Louise Draeger, Stine-Kathrein Kraeft, Chris Protzel, Oliver W Hakenberg
The cystadenoma of the testis and paratestis arising from an unequivocal oviduct-like structure, which is morphologically almost identical with those of the ovarian surface epithelium. These are very rare benign tumors of young adults. They present as asymptomatic cystic lesions. Bilateral paratesticular cystadenomas are strongly associated with von Hippel-Lindau syndrome and correlate with infertility. It is a neoplasm with low malignant potential. Most cystadenomas are benign but a few cases of malignant transformation of embryonic remnants have been reported in the appendix testis, including cases of adenocarcinoma, cystadenocarcinoma, and a low malignant müllerian-type epithelial tumor...
February 15, 2017: Urologia Internationalis
https://www.readbyqxmd.com/read/28196367/clinical-factors-predicting-tumour-upgrading-in-patients-under-active-surveillance-and-elected-to-active-treatment-after-disease-reclassification-or-progression
#5
Antonio Benito Porcaro, Francesca Cavicchioli, Nicolò De Luyk, Daniele Mattevi, Paolo Corsi, Marco Sebben, Alessandro Tafuri, Tania Processali, Davide Inverardi, Giovanni Cacciamani, Davide De Marchi, Matteo Balzarro, Maria A Cerruto, Matteo Brunelli, Giovanni Novella, Salvatore Siracusano, Walter Artibani
OBJECTIVES: To evaluate clinical factors associated with tumour upgrading (UPG) in low-intermediate risk patients who progressed while under active surveillance (AS) and underwent delayed radical prostatectomy. MATERIAL AND METHODS: The evaluated factors included prostate specific antigen (PSA), prostate volume, PSA density and number of biopsy positive cores (BPC). Multivariate logistic regression by the forward step Wald procedure was used. RESULTS: The study evaluated 24 patients who had UPG in 13 cases (54...
February 14, 2017: Urologia Internationalis
https://www.readbyqxmd.com/read/28190012/diagnostic-accuracy-of-transperineal-mri-fusion-biopsy-in-comparison-to-transrectal-biopsy-with-regard-to-incidental-histopathological-findings-in-transurethral-resection-of-the-prostate
#6
Svenja Christina Dieffenbacher, Ionel Valentin Popeneciu, Jan Philipp Radtke, Dogu Teber, Markus Hohenfellner, Boris Alexander Hadaschik, Gencay Hatiboglu
OBJECTIVE: To investigate the diagnostic accuracy of transperineal MRI/transrectal ultrasound (TRUS) fusion prostate biopsy vs. transrectal prostate biopsy in transurethral resection (TUR) specimen of men undergoing TUR of the prostate (TURP) for symptomatic bladder outlet obstruction. MATERIAL AND METHODS: From a database of 3,509 men receiving prostate biopsy, all those undergoing TURP and negative prostate biopsy (n = 95; 45 transrectal, 50 transperineal fusion) were analysed...
February 11, 2017: Urologia Internationalis
https://www.readbyqxmd.com/read/28161708/alterations-of-macrophage-migration-inhibitory-factor-expression-in-the-nervous-system-of-the-rat-cystitis-model
#7
Kwang Woo Lee, Woong Bin Kim, Sang Wook Lee, Jae Heon Kim, Jun Mo Kim, Young Ho Kim, Min Eui Kim
OBJECTIVE: We evaluated the changes in the migration inhibitory factor (MIF) expression with time in the bladder and spinal cord of a Sprague-Dawley rat cystitis model. METHODS: The bladder created by injecting lipopolysaccharide (LPS) and the lumbosacral spinal cord were removed at 4, 24, and 48 h, and 7 days after the induction of chronic cystitis, and 24 h after the induction of acute cystitis. The MIF expression was estimated using immunohistochemical staining, and the MIF mRNA was quantitatively analyzed using real-time polymerase chain reaction...
February 4, 2017: Urologia Internationalis
https://www.readbyqxmd.com/read/28152534/should-we-change-the-initial-treatment-of-renal-or-retroperitoneal-abscess-in-high-risk-patients
#8
Fukashi Yamamichi, Katsumi Shigemura, Koichi Kitagawa, Soichi Arakawa, Issei Tokimatsu, Masato Fujisawa
INTRODUCTION: This study examined the risk factors for initial treatment failure in renal or retroperitoneal abscess as a multicenter study. MATERIALS AND METHODS: This retrospective analysis investigated consecutive patients with renal or retroperitoneal abscess who were hospitalized in Japan. The outcomes of these patients were classified into "cured" and "failure or recurrence." The potential clinical risk factors examined were abscess size, diabetes mellitus, major organ failure, laboratory data, fever, drainage, and causative organisms, for instance...
February 3, 2017: Urologia Internationalis
https://www.readbyqxmd.com/read/28152527/effect-of-obesity-on-outcomes-of-percutaneous-nephrolithotomy-in-renal-stone-management-a-systematic-review-and-meta-analysis
#9
Xiangjun Zhou, Xinbo Sun, Xuhua Chen, Xiaoxin Gong, Yong Yang, Congbo Chen, Qisheng Yao
BACKGROUND: Percutaneous nephrolithotomy (PCNL) has been widely used to treat renal stones. The application of PCNL in obese patients results in the emergence of a number of challenges. This study compared the effect of obesity on the outcomes of PCNL in kidney stone treatment. METHODS: Eligible studies were searched in PubMed, Web of Science, and Cochrane Library databases. Data were analyzed using RevMan statistical software, weighted mean differences, ORs, and 95% CIs were calculated...
February 3, 2017: Urologia Internationalis
https://www.readbyqxmd.com/read/28152525/para-urethral-injections-with-urolastic%C3%A2-for-treatment-of-female-stress-urinary-incontinence-subjective-improvement-and-safety
#10
Allert M de Vries, Hendrikje M K van Breda, Jimmy G Fernandes, Pieter L Venema, John P F A Heesakkers
INTRODUCTION: Female stress urinary incontinence (SUI) is often treated surgically. Urethral bulking agents are a minimally invasive alternative, especially in patients suffering from intrinsic sphincter deficiency, but often with limited long-term efficacy. Urolastic® is a non-deformable, non-resorbable silicone elastomer that is used as an injectable. Its properties might result in a more durable response after injection. If this durability factor can be combined with a low complication rate, this can become a useful treatment option...
February 3, 2017: Urologia Internationalis
https://www.readbyqxmd.com/read/28147376/solifenacin-in-the-elderly-results-of-an-observational-study-measuring-efficacy-tolerability-and-cognitive-effects
#11
Christian Hampel, Dietmar Betz, Maximilian Burger, Christoph Nowak, Monika Vogel
INTRODUCTION: The study aimed to evaluate the efficacy and safety of solifenacin in older patients with overactive bladder (OAB). MATERIALS AND METHODS: Observational data on patients aged ≥70 years and the prescribed flexible dose of solifenacin for OAB were collected at 294 offices of German general practitioners. Baseline and week 12 data included type and severity of OAB symptoms, adverse events, quality of life, and change in cognitive function per Mini Mental State Examination (MMSE)...
February 2, 2017: Urologia Internationalis
https://www.readbyqxmd.com/read/28142149/cancer-stem-cells-in-prostate-cancer-implications-for-targeted-therapy
#12
Ricardo Leão, Célia Domingos, Arnaldo Figueiredo, Robert Hamilton, Uri Tabori, Pedro Castelo-Branco
Prostate cancer (PCa) is the most frequently diagnosed cancer in men and the second most common cause of cancer-related mortality among men in the developed world. Conventional anti-PCa therapies include surgery, radiation, hormonal ablation, and chemotherapy. Despite increasing efforts, these therapies are not effective for patients with advanced and/or metastatic disease. In most cases, cancer therapies fail due to an incomplete depletion of tumor cells, resulting in tumor relapse. The cancer stem cell (CSC) hypothesis is an emerging model that explains many of the molecular characteristics of oncological disease as well as the tendency of cancers to relapse, metastasize, and develop resistance to conventional therapies...
February 1, 2017: Urologia Internationalis
https://www.readbyqxmd.com/read/28142141/impact-of-prostate-involvement-on-outcomes-in-patients-treated-with-radical-cystoprostatectomy-for-bladder-cancer
#13
Marco Moschini, Shahrokh F Shariat, Massimo Freschi, Francesco Soria, Mohammad Abufaraj, Giorgio Gandaglia, Paolo Dell'Oglio, Agostino Mattei, Rocco Damiano, Andrea Salonia, Francesco Montorsi, Alberto Briganti, Andrea Gallina, Renzo Colombo
OBJECTIVE: The study aimed to evaluate the impact of the different types of prostate involvement at the time of radical cystoprostatectomy (RCP). METHODS: Data from 893 male patients treated with RCP at a referral center for bladder cancer (BCa) were assessed. Prostatic urothelial carcinoma (PUC) was stratified as stromal vs. urethral/duct involvements. Multivariable Cox regression analyses were built to test the impact of the presence of incidental prostate cancer (PCa) and PUC on survival outcomes...
February 1, 2017: Urologia Internationalis
https://www.readbyqxmd.com/read/28118624/durham-smith-vest-over-pant-technique-simple-procedure-for-a-complex-problem-post-hypospadias-repair-fistula
#14
Venkat A Gite, Saurabh R Patil, Sachin M Bote, Mohd Ayub Karam Nabi Siddiqui, Jayant V Nikose, Anitha J Kandi
OBJECTIVE: Urethrocutaneous fistula, which occurs after hypospadias surgery, is often a baffling problem and its treatment is challenging. The study aimed to evaluate the results of the simple procedure (Durham Smith vest-over-pant technique) for this complex problem (post-hypospadias repair fistula). METHODS: During the period from 2011 to 2015, 20 patients with post-hypospadias repair fistulas underwent Durham Smith repair. Common age group was between 5 and 12 years...
January 25, 2017: Urologia Internationalis
https://www.readbyqxmd.com/read/28095383/evaluation-of-plasmatic-kisspetin-10-as-a-biomarker-for-malignancy-and-subtype-differentiation-in-small-renal-tumours
#15
Marcus Horstmann, Felix Krause, Daniel Steinbach, Lars Twelker, Marc-Oliver Grimm
OBJECTIVE: To evaluate Kisspeptin-10 (Kiss-10) in patients with small renal tumours (SRTs) and controls. MATERIAL AND METHODS: Kiss-10 was measured in preoperative plasma samples in a cohort of 143 patients with unilateral renal tumours smaller than or equal to 4 cm and 40 age-matched controls by a competitive ELISA test kit. The cohort of patients included 56 patients with clear cell renal cell carcinoma (ccRCC), 43 with papillary RCC (pRCC), 12 with chromophobe RCC (chRCC) and 32 with oncocytomas...
January 18, 2017: Urologia Internationalis
https://www.readbyqxmd.com/read/28092914/paraneoplastic-cerebellar-degeneration-associated-with-pelvic-liposarcoma-a-rare-case-report
#16
Liang Zhou, Xin Wei, Nian-Wei Wu, Han-Mei Zhang, Bang-Hua Liao, Shu-Lian Chen, Hong Li, Yu-Chun Zhu, Kun-Jie Wang
Paraneoplastic cerebellar degeneration (PCD) is one of the most common paraneoplastic neurological syndromes characterized by the rapid development of severe cerebellar ataxia. In this report, a 23-year-old female with noticeable dizziness and gait instability was described. The enhanced CT scanning suggested the presence of a pelvic tumor. Then, PCD was established. Postoperative pathological result defined it as a liposarcoma (LS) with dedifferentiation. Interestingly, clinical symptoms disappeared after the surgical removal of the pelvic tumor...
January 17, 2017: Urologia Internationalis
https://www.readbyqxmd.com/read/28052297/androgen-receptor-gene-copy-number-and-protein-expression-in-treatment-na%C3%A3-ve-prostate-cancer
#17
Filip Poelaert, Candy Kumps, Nicolaas Lumen, Stephanie Verschuere, Louis Libbrecht, Marleen Praet, Sylvie Rottey, Tom Claeys, Piet Ost, Karel Decaestecker, Gert De Meerleer, Charles Van Praet
OBJECTIVES: To evaluate the androgen receptor (AR) gene copy number in androgen deprivation therapy (ADT) treatment-naïve prostate cancer (PCa) patients and to evaluate the corresponding AR protein expression and assess the association between these features and prognostic factors. MATERIALS AND METHODS: Chromosome X and AR gene copy number, using fluorescence-in-situ-hybridization, and epithelial-stromal AR expression, using AR immunohistochemistry, were analyzed in 62 ADT treatment-naïve PCa patients and 8 castration-refractory patients...
January 5, 2017: Urologia Internationalis
https://www.readbyqxmd.com/read/28052296/clinical-and-biochemical-influence-of-prostatic-stones
#18
Tomislav Soric, Mirnes Selimovic, Lada Bakovic, Tatjana Šimurina, Robert Selthofer, Jerka Dumic
INTRODUCTION: The study aimed to explore clinical influence of prostatic stones on lower urinary tract symptoms (LUTS), seminal plasma cytokines, and serum biomarkers. MATERIALS AND METHODS: A total of 70 men aged ≤50 years with LUTS divided into 2 groups: group with stones (GSt) and group without prostatic stones (GNoSt). All subjects completed the International Prostate Symptom Score (IPSS) questionnaire and National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI) scoring questionnaire...
January 5, 2017: Urologia Internationalis
https://www.readbyqxmd.com/read/28052290/impaction-and-prediction-does-ureteral-wall-thickness-affect-the-success-of-medical-expulsive-therapy-in-pediatric-ureteral-stones
#19
Aierken Tuerxun, Abudukahaer Batuer, Sakip Erturhan, Bilal Eryildirim, Emre Camur, Kemal Sarica
OBJECTIVE: The study aimed to evaluate the predictive value of ureteral wall thickness (UWT) and stone-related parameters for medical expulsive therapy (MET) success with an alpha blocker in pediatric upper ureteral stones. PATIENTS AND METHODS: A total of 35 children receiving MET ureteral stones (<10 mm) were evaluated. Patients were divided into 2 subgroups where MET was successful in 18 children (51.4%) and unsuccessful in 17 children (48.6%). Prior to management, stone size, stone density (in Hounsfield unit), degree of hydronephrosis, and UWT were evaluated with patient demographics and recorded...
January 5, 2017: Urologia Internationalis
https://www.readbyqxmd.com/read/28006778/a-systematic-review-and-meta-analysis-of-the-effects-on-dutasteride-treatment-for-reducing-surgical-blood-loss-during-transurethral-resection-of-the-prostate
#20
Jian Ren, Shicong Lai, Zhaoqiang Jiang, Xin Xu, Tongxiang Diao, Nikesh Thiruchelvam, Guan Zhang
OBJECTIVE: This systematic review and meta-analysis were performed to evaluate the efficacy of preoperative dutasteride treatment for reducing surgical blood loss in patients undergoing transurethral resection of the prostate (TURP). METHODS: A systematic search was performed from the electronic databases including PubMed, EMBASE, and Cochrane Library by May 2016. We followed the search strategy based on Preferred Reporting Items for Systematic Reviews and Meta-analysis statement when examining the literature...
December 23, 2016: Urologia Internationalis
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