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Urologia Internationalis

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https://www.readbyqxmd.com/read/28095383/evaluation-of-plasmatic-kisspetin-10-as-a-biomarker-for-malignancy-and-subtype-differentiation-in-small-renal-tumours
#1
Marcus Horstmann, Felix Krause, Daniel Steinbach, Lars Twelker, Marc-Oliver Grimm
OBJECTIVE: To evaluate Kisspeptin-10 (Kiss-10) in patients with small renal tumours (SRTs) and controls. MATERIAL AND METHODS: Kiss-10 was measured in preoperative plasma samples in a cohort of 143 patients with unilateral renal tumours smaller than or equal to 4 cm and 40 age-matched controls by a competitive ELISA test kit. The cohort of patients included 56 patients with clear cell renal cell carcinoma (ccRCC), 43 with papillary RCC (pRCC), 12 with chromophobe RCC (chRCC) and 32 with oncocytomas...
January 18, 2017: Urologia Internationalis
https://www.readbyqxmd.com/read/28092914/paraneoplastic-cerebellar-degeneration-associated-with-pelvic-liposarcoma-a-rare-case-report
#2
Liang Zhou, Xin Wei, Nian-Wei Wu, Han-Mei Zhang, Bang-Hua Liao, Shu-Lian Chen, Hong Li, Yu-Chun Zhu, Kun-Jie Wang
Paraneoplastic cerebellar degeneration (PCD) is one of the most common paraneoplastic neurological syndromes characterized by the rapid development of severe cerebellar ataxia. In this report, a 23-year-old female with noticeable dizziness and gait instability was described. The enhanced CT scanning suggested the presence of a pelvic tumor. Then, PCD was established. Postoperative pathological result defined it as a liposarcoma (LS) with dedifferentiation. Interestingly, clinical symptoms disappeared after the surgical removal of the pelvic tumor...
January 17, 2017: Urologia Internationalis
https://www.readbyqxmd.com/read/28052297/androgen-receptor-gene-copy-number-and-protein-expression-in-treatment-na%C3%A3-ve-prostate-cancer
#3
Filip Poelaert, Candy Kumps, Nicolaas Lumen, Stephanie Verschuere, Louis Libbrecht, Marleen Praet, Sylvie Rottey, Tom Claeys, Piet Ost, Karel Decaestecker, Gert De Meerleer, Charles Van Praet
OBJECTIVES: To evaluate the androgen receptor (AR) gene copy number in androgen deprivation therapy (ADT) treatment-naïve prostate cancer (PCa) patients and to evaluate the corresponding AR protein expression and assess the association between these features and prognostic factors. MATERIALS AND METHODS: Chromosome X and AR gene copy number, using fluorescence-in-situ-hybridization, and epithelial-stromal AR expression, using AR immunohistochemistry, were analyzed in 62 ADT treatment-naïve PCa patients and 8 castration-refractory patients...
January 5, 2017: Urologia Internationalis
https://www.readbyqxmd.com/read/28052296/clinical-and-biochemical-influence-of-prostatic-stones
#4
Tomislav Soric, Mirnes Selimovic, Lada Bakovic, Tatjana Šimurina, Robert Selthofer, Jerka Dumic
INTRODUCTION: The study aimed to explore clinical influence of prostatic stones on lower urinary tract symptoms (LUTS), seminal plasma cytokines, and serum biomarkers. MATERIALS AND METHODS: A total of 70 men aged ≤50 years with LUTS divided into 2 groups: group with stones (GSt) and group without prostatic stones (GNoSt). All subjects completed the International Prostate Symptom Score (IPSS) questionnaire and National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI) scoring questionnaire...
January 5, 2017: Urologia Internationalis
https://www.readbyqxmd.com/read/28052290/impaction-and-prediction-does-ureteral-wall-thickness-affect-the-success-of-medical-expulsive-therapy-in-pediatric-ureteral-stones
#5
Aierken Tuerxun, Abudukahaer Batuer, Sakip Erturhan, Bilal Eryildirim, Emre Camur, Kemal Sarica
OBJECTIVE: The study aimed to evaluate the predictive value of ureteral wall thickness (UWT) and stone-related parameters for medical expulsive therapy (MET) success with an alpha blocker in pediatric upper ureteral stones. PATIENTS AND METHODS: A total of 35 children receiving MET ureteral stones (<10 mm) were evaluated. Patients were divided into 2 subgroups where MET was successful in 18 children (51.4%) and unsuccessful in 17 children (48.6%). Prior to management, stone size, stone density (in Hounsfield unit), degree of hydronephrosis, and UWT were evaluated with patient demographics and recorded...
January 5, 2017: Urologia Internationalis
https://www.readbyqxmd.com/read/28006778/a-systematic-review-and-meta-analysis-of-the-effects-on-dutasteride-treatment-for-reducing-surgical-blood-loss-during-transurethral-resection-of-the-prostate
#6
Jian Ren, Shicong Lai, Zhaoqiang Jiang, Xin Xu, Tongxiang Diao, Nikesh Thiruchelvam, Guan Zhang
OBJECTIVE: This systematic review and meta-analysis were performed to evaluate the efficacy of preoperative dutasteride treatment for reducing surgical blood loss in patients undergoing transurethral resection of the prostate (TURP). METHODS: A systematic search was performed from the electronic databases including PubMed, EMBASE, and Cochrane Library by May 2016. We followed the search strategy based on Preferred Reporting Items for Systematic Reviews and Meta-analysis statement when examining the literature...
December 23, 2016: Urologia Internationalis
https://www.readbyqxmd.com/read/27992871/erbb2-expression-as-potential-risk-stratification-for-early-cystectomy-in-patients-with-pt1-bladder-cancer-and-concomitant-carcinoma-in-situ
#7
Johannes Breyer, Wolfgang Otto, Ralph M Wirtz, Bernd Wullich, Bastian Keck, Philipp Erben, Maximilian C Kriegmair, Robert Stoehr, Markus Eckstein, Mark Laible, Kornelia Schlombs, Sebastian Eidt, Stefan Denzinger, Maximilian Burger, Arndt Hartmann
: Background/Aims/Objectives: It is difficult to identify patients with a non-muscle-invasive bladder cancer (NMIBC) at stage pT1 with concomitant carcinoma in situ (Cis) who will benefit from an early cystectomy. METHODS: We retrospectively analyzed clinical data and formalin-fixed paraffin-embedded tissues of patients with NMIBC. Messenger ribonucleic acid (mRNA) expression of progesterone receptor (PGR), estrogen receptor (ESR1), ERBB2, and marker of proliferation Ki-67 (MKI67) was measured by single-step reverse transcription quantitative real-time polymerase chain reaction using RNA-specific TaqMan assays...
December 17, 2016: Urologia Internationalis
https://www.readbyqxmd.com/read/27988516/laparoscopic-extravesical-submucosal-tunneling-ureteroneocystostomy-combined-with-psoas-hitch-for-medium-length-distal-ureteral-defects-in-adults
#8
Huijie Gong, Yiqin Lu, Yongji Yan, Zhenqi Wu, Wenfeng Gao, Haisheng Cheng, Yabing Wu, Yanfeng Li, Xuetao Ma, Jingbo Liu, Linfeng Dai
OBJECTIVE: This study aims to describe the technique and feasibility of laparoscopic submucosal tunneling ureteroneocystostomy in combination with psoas hitch to restore urinary tract continuity in patients showing medium-length distal ureteral defects. MATERIALS AND METHODS: From January 2012 to April 2016, a total of 13 patients (4 males and 9 females) with a mean age of 37 years were performed with the laparoscopic operation of ureteral submucosal tunneling reimplantation combined with psoas hitch...
December 17, 2016: Urologia Internationalis
https://www.readbyqxmd.com/read/27951584/90-day-mortality-after-radical-cystectomy-for-bladder-cancer-prognostic-factors-in-a-multicenter-case-series
#9
Carolina D'Elia, Evi Comploj, Maria Angela Cerruto, Emanuela Trenti, Salvatore Mario Palermo, Roberto Melotti, Walter Artibani, Armin Pycha
OBJECTIVES: To identify preoperative risk factors for 90-day mortality and to validate existing nomograms in a multicenter series of patients undergoing radical cystectomy (RC). MATERIALS AND METHODS: We evaluated 90-day mortality in 475 patients following RC and urinary diversion at 2 Italian institutions and validated Aziz and Isbarn nomogram. Univariable logistic models assessed the predictive ability of operative volume, age at intervention, gender, body mass index, carcinoma in situ at transurethral resection of the bladder, American Society of Anesthesiologist (ASA) score, Charlson Comorbidity Index, clinical stage and pathological stage (TNM)...
December 13, 2016: Urologia Internationalis
https://www.readbyqxmd.com/read/27951542/critical-analysis-of-a-series-of-early-inguinal-ureterostomies-are-they-useful-and-how-well-are-they-tolerated
#10
Aurore Bouty, Yan Lefevre, Luke Harper, Antoine Tran, Pierre Vergnes, Eric Dobremez
INTRODUCTION: The study aimed to evaluate the advantages of temporary inguinal ureterostomy in the management of neonates with uropathies and early or recurrent pyelonephritis. PATIENTS AND METHODS: We performed a retrospective analysis of all patients who underwent ureterostomies between 1989 and 2012, with specific regards to indications and outcomes. We also performed a survey of parents to evaluate their acceptance of diversion. RESULTS: We included 18 patients (12 primary high-grade vesicoureteral reflux [VUR] and 6 primary obstructive megaureters [MUs])...
December 13, 2016: Urologia Internationalis
https://www.readbyqxmd.com/read/27924801/scrotum-melanoma-evolution-over-one-year-in-this-unusual-location
#11
Leopoldo José Marzullo Zucchet, Miguel Ángel Bonillo García, Laura Lorenzo Soriano, Enrique Broseta Rico
Genitourinary melanoma accounts for 0.1-0.2% of melanoma, the scrotum being its rarest location. We report about an 85-year-old patient who was referred to our outpatient clinic due to the presence of a scrotum black papule for 20 months. Wide local excision was performed, and histology revealed a malignant melanoma. Chest and abdominal CT revealed metastatic disease, so chemotherapy, immunotherapy and radiotherapy were administered. We describe the evolution over 1 year in this unusual location, as well as complications and the currently available therapeutic options to cure this disease...
December 8, 2016: Urologia Internationalis
https://www.readbyqxmd.com/read/27907923/association-between-the-surgical-apgar-score-and-perioperative-complications-after-radical-prostatectomy
#12
Matthias Orberger, Jüri Palisaar, Florian Roghmann, Ludger Mittelstädt, Petra Bischoff, Joachim Noldus, Björn Löppenberg
OBJECTIVE: To evaluate whether the Surgical Apgar Score (SAS) can identify patients who are at risk for perioperative adverse events (PAE) following radical prostatectomy for prostate cancer. PATIENTS AND METHODS: At a single academic institution, 994 patients undergoing radical prostatectomy between 2010 and 2013 were analyzed retrospectively. The SAS was calculated from anesthesia records, evaluated to predict PAE within a 30-day time period postoperatively; these events were classified according to standardized classification systems...
December 2, 2016: Urologia Internationalis
https://www.readbyqxmd.com/read/27894122/b-cell-lymphoma-2-modified-bone-marrow-derived-mesenchymal-stem-cells-transplantation-for-the-treatment-of-diabetes-mellitus-induced-erectile-dysfunction-in-a-rat-model
#13
Xiang Sun, Long-Hua Luo, Liang Feng, Dong-Shui Li, Ke-Zhao Zhong
OBJECTIVE: The study aimed to explore the effects of B cell lymphoma-2 (Bcl-2)-modified bone marrow-derived mesenchymal stem cells (BMSCs) transplantation for the treatment of diabetes mellitus-induced erectile dysfunction (DMED) in a rat model. METHODS: The DMED rat model was successfully established. Thirty-six DMED rats were assigned into the Bcl-2-BMSCs, null-BMSCs, BMSCs and phosphate buffered saline (PBS) groups. Meanwhile, 9 normal rats injected with PBS were taken as the normal control group...
November 29, 2016: Urologia Internationalis
https://www.readbyqxmd.com/read/27889781/striated-muscle-in-radical-prostatectomy-specimens-a-marker-of-apical-dissection-quality-and-an-independent-predictor-of-urinary-continence-after-endoscopic-extraperitoneal-radical-prostatectomy
#14
Daniel W Good, Andrew Wood, Laurence Stewart, Jens-Uwe Stolzenburg, Roman Ganzer, Jochen Neuhaus, Grant D Stewart, S Alan McNeill
INTRODUCTION: The study aimed to determine if the presence and amount of striated muscle on the apical sections of the cruciate sections of laparoscopic radical prostatectomy (LRP) specimens predict early and long-term urinary continence outcomes. PATIENTS AND METHODS: We conducted a retrospective review of our prospectively collected single surgeon LRP database. We identified patients based on their continence outcomes (continent (0 pads) or incontinent at 12 months), with an approximate even spread early continent and incontinent patients)...
November 26, 2016: Urologia Internationalis
https://www.readbyqxmd.com/read/27884015/joseph-fr%C3%A3-d%C3%A3-ric-beno%C3%A3-t-charri%C3%A3-re-how-to-explain-his-success-as-one-of-the-most-famous-surgical-instrument-makers-regarding-his-life-from-childhood-to-death
#15
Jasmin Katrin Badawi
INTRODUCTION: We use the name 'Charrière' every day as a unit of measurement. This article explains his success as one of the most famous instrument makers who ever lived. MATERIALS AND METHODS: A review of the literature was completed using PubMed. Additionally, material of historical sources like the museum of Bulle was used. RESULTS: Joseph-Frédéric-Benoît Charrière was born in Switzerland in 1803. At the age of 13, he moved to Paris and learned the profession of a cutler...
November 25, 2016: Urologia Internationalis
https://www.readbyqxmd.com/read/27880958/factors-influencing-repair-outcomes-of-vesicovaginal-fistula-a-retrospective-review-of-139-procedures
#16
Liang Zhou, Tong-Xin Yang, De-Yi Luo, Shu-Lian Chen, Bang-Hua Liao, Hong Li, Kun-Jie Wang, Hong Shen
INTRODUCTION: We aimed to report the outcomes of patients undergoing vesicovaginal fistula (VVF) repair to identify prognostic factors. MATERIALS AND METHODS: Patients who underwent VVF repair between January 2009 and October 2015 were reviewed. Primary outcome was fistula closure at 3 months. RESULTS: A total of 123 patients and 139 procedures of VVF repair were reviewed. The overall success rate was 85.6%. There were no significant differences in age (p = 0...
November 24, 2016: Urologia Internationalis
https://www.readbyqxmd.com/read/27871076/semi-rigid-ureteroscopy-for-proximal-ureteral-stones-does-adjunctive-tamsulosin-therapy-increase-the-chance-of-success
#17
Abul-Fotouh Ahmed, Aref Maarouf, Essam Shalaby, Saad Alshahrani, Mohamed El-Feky, Sabri Khaled, Abdullah Daoud, Ahmed Soliman, Esam Desoky, Hisham El-Helaly
OBJECTIVES: To assess the efficacy of adjunctive tamsulosin therapy in improving the success rate of laser-assisted semi-rigid ureteroscopy (URS) for removing proximal ureteral stones. PATIENTS AND METHODS: This prospective study included 165 patients with proximal ureteral stones ≥10 mm. The patients were randomly assigned to a tamsulosin group (Group I, n = 81) receiving tamsulosin 0.4 mg daily for 1 week pre-URS and a control group (Group II, n = 84) without tamsulosin therapy...
November 22, 2016: Urologia Internationalis
https://www.readbyqxmd.com/read/27842318/prevention-of-recurrent-bladder-tumors-after-nephroureterectomy-for-primary-upper-urinary-tract-urothelial-carcinoma-an-individualized-selection-strategy-based-on-patient-risk-stratification-is-needed
#18
Xingbo Long, Lin Qi, Xiongbing Zu, Yuan Li, Wei He, Shuohuang Pi, Xiang Chen, Kebing Zhou, Xiheng Hu, Minfeng Chen
OBJECTIVE: To evaluate the efficacies of different chemotherapy regimens in different risk sub-groups for the prevention of bladder recurrence after radical nephroureterectomy (RNU). MATERIALS AND METHODS: Between 2004 and 2012, we recruited 685 patients who underwent RNU for upper tract urothelial carcinoma at 4 Chinese institutions. We assessed whether the type of intravesical chemotherapy regimen affected the bladder recurrence rate in patients with different risk levels after RNU...
November 15, 2016: Urologia Internationalis
https://www.readbyqxmd.com/read/27806367/feasibility-and-efficacy-of-a-urologic-profession-campaign-on-cryptorchidism-using-internet-and-social-media
#19
Hendrik Borgmann, Sabine Kliesch, Stephan Roth, Mael Roth, Stephan Degener
INTRODUCTION: We performed a professional campaign in Germany intending to establish the urologic profession as a competent and helpful point of contact for patients with cryptorchidism. The aim of this study was to assess the feasibility of this campaign and to quantify the efficacy of using Internet vs. social media. MATERIALS AND METHODS: The strategic design of the campaign comprised a strategy meeting, creation of a landing page, and targeted advertisements on Google in the form of Adwords and on Facebook in the form of sidebar ads and sponsored posts...
November 3, 2016: Urologia Internationalis
https://www.readbyqxmd.com/read/27798945/comparison-of-yag-laser-lithotripsy-and-extracorporeal-shock-wave-lithotripsy-in-treatment-of-ureteral-calculi-a-meta-analysis
#20
Chao Yang, Shijun Li, Yingdong Cui
OBJECTIVE: To evaluate the clinical efficiency and safety of ureteroscopy lithotripsy (URSL) with holmium laser technology and extracorporeal shock wave lithotripsy (ESWL) on ureteral calculi using systematic reviews. METHODS: Randomized controlled trials and prospective controlled trials accorded with inclusion among PubMed Database, EmBase Database, Cochrane Library and China National Knowledge Infrastructure were collected. Review Manager 5.0 was adopted to estimate the effects of the results among selected articles...
November 1, 2016: Urologia Internationalis
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