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Radiation and Environmental Biophysics

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https://www.readbyqxmd.com/read/28526979/the-probabilities-of-one-and-multi-track-events-for-modeling-radiation-induced-cell-kill
#1
Uwe Schneider, Fabiano Vasi, Jürgen Besserer
In view of the clinical importance of hypofractionated radiotherapy, track models which are based on multi-hit events are currently reinvestigated. These models are often criticized, because it is believed that the probability of multi-track hits is negligible. In this work, the probabilities for one- and multi-track events are determined for different biological targets. The obtained probabilities can be used with nano-dosimetric cluster size distributions to obtain the parameters of track models. We quantitatively determined the probabilities for one- and multi-track events for 100, 500 and 1000 keV electrons, respectively...
May 19, 2017: Radiation and Environmental Biophysics
https://www.readbyqxmd.com/read/28526978/cytogenetic-biodosimetry-and-dose-rate-effect-after-radioiodine-therapy-for-thyroid-cancer
#2
Igor K Khvostunov, Vladimir A Saenko, Valeri Krylov, Andrei Rodichev, Shunichi Yamashita
This study set out to investigate chromosomal damage in peripheral blood lymphocytes of thyroid cancer patients receiving (131)I for thyroid remnant ablation or treatment of metastatic disease. The observed chromosomal damage was further converted to the estimates of whole-body dose to project the adverse side effects. Chromosomal aberration analysis was performed in 24 patients treated for the first time or after multiple courses. Blood samples were collected before treatment and 3 or 4 days after administration of 2-4 GBq of (131)I...
May 19, 2017: Radiation and Environmental Biophysics
https://www.readbyqxmd.com/read/28500389/degradation-of-phospholipids-under-different-types-of-irradiation-and-varying-oxygen-saturation
#3
Luděk Vyšín, Kateřina Tomanová, Tereza Pavelková, Richard Wagner, Marie Davídková, Viliam Múčka, Václav Čuba, Libor Juha
The effects of different types of radiation on the formation of peroxide forms of 2-dioleoyl-sn-glycero-3-phosphocholine were studied under various conditions. For the irradiation, an aqueous solution of small unilamellar vesicles was prepared. Variations in parameters such as the dose rate and molecular oxygen saturation levels were evaluated. Our study suggests that the mechanism of the peroxides formation process remains unchanged under irradiation by accelerated electrons, gamma and accelerated protons...
May 12, 2017: Radiation and Environmental Biophysics
https://www.readbyqxmd.com/read/28493137/effective-dose-rate-coefficients-for-exposure-to-contaminated-soil
#4
K G Veinot, K F Eckerman, M B Bellamy, M M Hiller, S A Dewji, C E Easterly, N E Hertel, R Manger
The Oak Ridge National Laboratory Center for Radiation Protection Knowledge has undertaken calculations related to various environmental exposure scenarios. A previous paper reported the results for submersion in radioactive air and immersion in water using age-specific mathematical phantoms. This paper presents age-specific effective dose rate coefficients derived using stylized mathematical phantoms for exposure to contaminated soils. Dose rate coefficients for photon, electron, and positrons of discrete energies were calculated and folded with emissions of 1252 radionuclides addressed in ICRP Publication 107 to determine equivalent and effective dose rate coefficients...
May 10, 2017: Radiation and Environmental Biophysics
https://www.readbyqxmd.com/read/28374124/external-dose-reconstruction-for-the-former-village-of-metlino-techa-river-russia-based-on-environmental-surveys-luminescence-measurements-and-radiation-transport-modelling
#5
M M Hiller, C Woda, N G Bougrov, M O Degteva, O Ivanov, A Ulanovsky, S Romanov
In the first years of its operation, the Mayak Production Association, a facility part of the Soviet nuclear weapons program in the Southern Urals, Russia, discharged large amounts of radioactively contaminated effluent into the nearby Techa River, thus exposing the people living at this river to external and internal radiations. The Techa River Cohort is a cohort intensely studied in epidemiology to investigate the correlation between low-dose radiation and health effects on humans. For the individuals in the cohort, the Techa River Dosimetry System describes the accumulated dose in human organs and tissues...
May 2017: Radiation and Environmental Biophysics
https://www.readbyqxmd.com/read/28337587/erratum-to-internal-exposure-to-neutron-activated-56-mn-dioxide-powder-in-wistar-rats-part%C3%A2-2-pathological-effects
#6
Kazuko Shichijo, Nariaki Fujimoto, Darkhan Uzbekov, Ynkar Kairkhanova, Aisulu Saimova, Nailya Chaizhunusova, Nurlan Sayakenov, Dariya Shabdarbaeva, Nurlan Aukenov, Almas Azimkhanov, Alexander Kolbayenkov, Zhanna Mussazhanova, Daisuke Niino, Masahiro Nakashima, Kassym Zhumadilov, Valeriy Stepanenko, Masao Tomonaga, Tolebay Rakhypbekov, Masaharu Hoshi
No abstract text is available yet for this article.
May 2017: Radiation and Environmental Biophysics
https://www.readbyqxmd.com/read/28337586/the-role-of-fluoride-and-chlorhexidine-in-preserving-hardness-and-mineralization-of-enamel-and-cementum-after-gamma-irradiation
#7
Rowida Abdalla, Maha A Niazy, Wael E Jamil, Hala A Hazzaa, Amal A Elbatouti
The purpose of this study was to evaluate the effect of 0.05% sodium fluoride and 0.12% chlorhexidine mouthwashes on the micro-hardness of tooth enamel and cementum that was exposed to therapeutic doses of gamma radiation. Sixty extracted human teeth were divided into two groups, one was irradiated, the other was not irradiated. The two groups were further subdivided into three subgroups, which were each treated either with 0.05% sodium fluoride or with 0.12% chlorhexidine; the third subgroup served as a control...
May 2017: Radiation and Environmental Biophysics
https://www.readbyqxmd.com/read/28337585/background-gamma-radiation-and-childhood-cancer-in-germany-an-ecological-study
#8
Claudia Spix, Bernd Grosche, Martin Bleher, Peter Kaatsch, Peter Scholz-Kreisel, Maria Blettner
The relationship of low-dose background gamma radiation and childhood leukaemia was investigated in a number of studies. Results from these studies are inconclusive. Therefore, in the present study 25 years of German childhood cancer data were analyzed using interpolated background annual gamma dose rate per community in an ecological study. The main question was leukaemia; as exploratory questions we investigate central nervous system (CNS) tumours, thyroid carcinomas and diagnoses less likely to be related to radiation...
May 2017: Radiation and Environmental Biophysics
https://www.readbyqxmd.com/read/28283750/the-effects-of-simulating-a-realistic-eye-model-on-the-eye-dose-of-an-adult-male-undergoing-head-computed-tomography
#9
Parisa Akhlaghi, Atiyeh Ebrahimi-Khankook, Alireza Vejdani-Noghreiyan
In head computed tomography, radiation upon the eye lens (as an organ with high radiosensitivity) may cause lenticular opacity and cataracts. Therefore, quantitative dose assessment due to exposure of the eye lens and surrounding tissue is a matter of concern. For this purpose, an accurate eye model with realistic geometry and shape, in which different eye substructures are considered, is needed. To calculate the absorbed radiation dose of visual organs during head computed tomography scans, in this study, an existing sophisticated eye model was inserted at the related location in the head of the reference adult male phantom recommended by the International Commission on Radiological Protection (ICRP)...
May 2017: Radiation and Environmental Biophysics
https://www.readbyqxmd.com/read/28271222/in-memoriam-ilya-aronovich-likhtarev-1935-2017
#10
LETTER
Mikhail I Balonov, Volodymyr Berkovskyy, André Bouville, Lynn R Anspaugh, Herwig G Paretzke
No abstract text is available yet for this article.
May 2017: Radiation and Environmental Biophysics
https://www.readbyqxmd.com/read/28258386/assessing-the-combined-effect-of-extremely-low-frequency-magnetic-field-exposure-and-oxidative-stress-on-line-1-promoter-methylation-in-human-neural-cells
#11
Gianfranco Giorgi, Chiara Pirazzini, Maria Giulia Bacalini, Cristina Giuliani, Paolo Garagnani, Miriam Capri, Ferdinando Bersani, Brunella Del Re
Extremely low frequency magnetic fields (ELF-MF) have been classified as "possibly carcinogenic", but their genotoxic effects are still unclear. Recent findings indicate that epigenetic mechanisms contribute to the genome dysfunction and it is well known that they are affected by environmental factors. To our knowledge, to date the question of whether exposure to ELF-MF can influence epigenetic modifications has been poorly addressed. In this paper, we investigated whether exposure to ELF-MF alone and in combination with oxidative stress (OS) can affect DNA methylation, which is one of the most often studied epigenetic modification...
May 2017: Radiation and Environmental Biophysics
https://www.readbyqxmd.com/read/28258385/radioactivity-in-mushrooms-from-selected-locations-in-the-bohemian-forest-czech-republic
#12
Michaela Čadová, Renata Havránková, Jiří Havránek, Friedo Zölzer
(137)Cs is one of the most important radionuclides released in the course of atmospheric nuclear weapon tests and during accidents in nuclear power plants such as that in Chernobyl, Ukraine, or Fukushima, Japan. The aim of this study was to compare (137)Cs and (40)K concentrations in particular species of mushrooms from selected locations in the Bohemian Forest (Czech: Šumava), Czech Republic, where a considerable contamination from the Chernobyl accident had been measured in 1986. Samples were collected between June and October 2014...
May 2017: Radiation and Environmental Biophysics
https://www.readbyqxmd.com/read/28124098/measurements-of-radon-activity-concentration-in-mouse-tissues-and-organs
#13
Yuu Ishimori, Hiroshi Tanaka, Akihiro Sakoda, Takahiro Kataoka, Kiyonori Yamaoka, Fumihiro Mitsunobu
The purpose of this study is to investigate the biokinetics of inhaled radon, radon activity concentrations in mouse tissues and organs were determined after mice had been exposed to about 1 MBq/m(3) of radon in air. Radon activity concentrations in mouse blood and in other tissues and organs were measured with a liquid scintillation counter and with a well-type HP Ge detector, respectively. Radon activity concentration in mouse blood was 0.410 ± 0.016 Bq/g when saturated with 1 MBq/m(3) of radon activity concentration in air...
May 2017: Radiation and Environmental Biophysics
https://www.readbyqxmd.com/read/28184999/rosiglitazone-enhances-radiosensitivity-by-inhibiting-repair-of-dna-damage-in-cervical-cancer-cells
#14
Zhengzhe An, Jae-Ran Yu, Woo-Yoon Park
Radiation therapy (RT) is one of the main treatment modalities for cervical cancer. Rosiglitazone (ROSI) has been reported to have antiproliferative effects against various types of cancer cells and also to induce antioxidant enzymes that can scavenge reactive oxygen species (ROS) and thereby modify radiosensitivity. Here, we explored the effect of ROSI on radiosensitivity and the underlying mechanisms in cervical cancer cells. Three cervical cancer cell lines (ME-180, HeLa, and SiHa) were used. The cells were pretreated with ROSI and then irradiated...
March 2017: Radiation and Environmental Biophysics
https://www.readbyqxmd.com/read/28180988/internal-exposure-to-neutron-activated-56-mn-dioxide-powder-in-wistar-rats-part%C3%A2-2-pathological-effects
#15
Kazuko Shichijo, Nariaki Fujimoto, Darkhan Uzbekov, Ynkar Kairkhanova, Aisulu Saimova, Nailya Chaizhunusova, Nurlan Sayakenov, Dariya Shabdarbaeva, Nurlan Aukenov, Almas Azimkhanov, Alexander Kolbayenkov, Zhanna Mussazhanova, Daisuke Niino, Masahiro Nakashima, Kassym Zhumadilov, Valeriy Stepanenko, Masao Tomonaga, Tolebay Rakhypbekov, Masaharu Hoshi
To fully understand the radiation effects of the atomic bombing of Hiroshima and Nagasaki among the survivors, radiation from neutron-induced radioisotopes in soil and other materials should be considered in addition to the initial radiation directly received from the bombs. This might be important for evaluating the radiation risks to the people who moved to these cities soon after the detonations and probably inhaled activated radioactive "dust." Manganese-56 is known to be one of the dominant radioisotopes produced in soil by neutrons...
March 2017: Radiation and Environmental Biophysics
https://www.readbyqxmd.com/read/28040836/measurement-of-131-i-activity-in-thyroid-of-nuclear-medical-staff-and-internal-dose-assessment-in-a-polish-nuclear-medical-hospital
#16
K Brudecki, A Kowalska, P Zagrodzki, A Szczodry, T Mroz, P Janowski, J W Mietelski
This paper presents results of (131)I thyroid activity measurements in 30 members of the nuclear medicine personnel of the Department of Endocrinology and Nuclear Medicine Holy Cross Cancer Centre in Kielce, Poland. A whole-body spectrometer equipped with two semiconductor gamma radiation detectors served as the basic research instrument. In ten out of 30 examined staff members, the determined (131)I activity was found to be above the detection limit (DL = 5 Bq of (131)I in the thyroid). The measured activities ranged from (5 ± 2) Bq to (217 ± 56) Bq...
March 2017: Radiation and Environmental Biophysics
https://www.readbyqxmd.com/read/28012073/-131-i-age-dependent-inhalation-dose-in-southern-poland-from-fukushima-accident
#17
K Brudecki, K Szufa, J W Mietelski
A general method for calculating doses absorbed from isotopes released in nuclear accidents is presented. As an example, this method was used to calculate doses for inhabitants of Southern Poland due to inhalation of (131)I released due to the Fukushima nuclear plant accident. (131)I activity measurements in the air of that region provided the basis for the study. The proposed model is based on a complex biokinetic model for iodine merging the Leggett model developed in 2010 with the human respiratory tract and gastrointestinal tract models recommended by the International Commission on Radiological Protection (ICRP)...
March 2017: Radiation and Environmental Biophysics
https://www.readbyqxmd.com/read/28188481/internal-exposure-to-neutron-activated-56-mn-dioxide-powder-in-wistar-rats-part%C3%A2-1-dosimetry
#18
Valeriy Stepanenko, Tolebay Rakhypbekov, Keiko Otani, Satoru Endo, Kenichi Satoh, Noriyuki Kawano, Kazuko Shichijo, Masahiro Nakashima, Toshihiro Takatsuji, Aya Sakaguchi, Hiroaki Kato, Yuichi Onda, Nariaki Fujimoto, Shin Toyoda, Hitoshi Sato, Altay Dyussupov, Nailya Chaizhunusova, Nurlan Sayakenov, Darkhan Uzbekov, Aisulu Saimova, Dariya Shabdarbaeva, Mazhin Skakov, Alexandr Vurim, Vyacheslav Gnyrya, Almas Azimkhanov, Alexander Kolbayenkov, Kasym Zhumadilov, Yankar Kairikhanova, Andrey Kaprin, Vsevolod Galkin, Sergey Ivanov, Timofey Kolyzhenkov, Aleksey Petukhov, Elena Yaskova, Irina Belukha, Artem Khailov, Valeriy Skvortsov, Alexander Ivannikov, Umukusum Akhmedova, Viktoria Bogacheva, Masaharu Hoshi
There were two sources of ionizing irradiation after the atomic bombings of Hiroshima and Nagasaki: (1) initial gamma-neutron irradiation at the moment of detonation and (2) residual radioactivity. Residual radioactivity consisted of two components: radioactive fallout containing fission products, including radioactive fissile materials from nuclear device, and neutron-activated radioisotopes from materials on the ground. The dosimetry systems DS86 and DS02 were mainly devoted to the assessment of initial radiation exposure to neutrons and gamma rays, while only brief considerations were given for the estimation of doses caused by residual radiation exposure...
February 10, 2017: Radiation and Environmental Biophysics
https://www.readbyqxmd.com/read/28185000/calculation-on-spectrum-of-direct-dna-damage-induced-by-low-energy-electrons-including-dissociative-electron-attachment
#19
Wei Liu, Zhenyu Tan, Liming Zhang, Christophe Champion
In this work, direct DNA damage induced by low-energy electrons (sub-keV) is simulated using a Monte Carlo method. The characteristics of the present simulation are to consider the new mechanism of DNA damage due to dissociative electron attachment (DEA) and to allow determining damage to specific bases (i.e., adenine, thymine, guanine, or cytosine). The electron track structure in liquid water is generated, based on the dielectric response model for describing electron inelastic scattering and on a free-parameter theoretical model and the NIST database for calculating electron elastic scattering...
February 9, 2017: Radiation and Environmental Biophysics
https://www.readbyqxmd.com/read/28144741/the-influence-of-reference-radiation-photon-energy-on-high-let-rbe-comparison-of-human-peripheral-lymphocytes-and-human-hamster-hybrid-al-cells
#20
T E Schmid, C Greubel, G Dollinger, E Schmid
The relative biological effectiveness (RBE) based on the induction of dicentrics in any cell type is principally an important information for the increasing application of high-LET radiation in cancer therapy. Since the standard system of human lymphocytes for measuring dicentrics are not compatible with our microbeam irradiation setup where attaching cells are essential, we used human-hamster hybrid AL cells which do attach on foils and fulfil the special experimental requirement for microbeam irradiations...
January 31, 2017: Radiation and Environmental Biophysics
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