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Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques

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https://www.readbyqxmd.com/read/29325600/clival-chordoma-with-brainstem-invasion
#1
Amit R L Persad, Bradford Mechor, Yves Starreveld
No abstract text is available yet for this article.
January 12, 2018: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://www.readbyqxmd.com/read/29307332/an-overview-of-psychogenic-non-epileptic-seizures-etiology-diagnosis-and-management
#2
Ángela Milán-Tomás, Michelle Persyko, Martin Del Campo, Colin M Shapiro, Karl Farcnik
The purpose of this review is to provide an update of the research regarding the etiology, diagnosis and management of psychogenic non-epileptic seizures (PNES). A literature search using Pubmed, Ovid MEDLINE and EMBASE database was performed from 2000 up to August 2017. We have evaluated the different factors leading to PNES as well as the diagnostic approach and management of this disorder which continue to be very difficult. The coexistence of epilepsy and PNES poses special challenges and requires the coordinated efforts of the family physicians, psychiatrists, psychologists and neurologists...
January 8, 2018: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://www.readbyqxmd.com/read/29307326/neurolymphomatosis-of-the-brachial-plexus-and-its-branches-case-series-and-literature-review
#3
Pierre R Bourque, Jodi Warman Chardon, Mark Bryanton, Melissa Toupin, Bruce F Burns, Carlos Torres
BACKGROUND: Neurolymphomatosis is a process of neoplastic endoneurial invasion, most strongly associated with non-Hodgkin's lymphoma. It must be distinguished from paraneoplastic, metabolic, nutritional and treatment-related causes of neuropathy that are common in this patient population. METHODS: This brief case series illustrates the protean manifestations of neurolymphomatosis of the brachial plexus, ranging from focal distal mononeuropathy to multifocal brachial plexopathy, either as the index manifestation of lymphoma or as a complication of relapsing disease...
January 8, 2018: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://www.readbyqxmd.com/read/29307325/anxiety-and-depression-in-adult-first-seizure-presentations
#4
Ciaran Lane, Candice Crocker, Karen Legg, Mallory Borden, Bernd Pohlmann-Eden
OBJECTIVE: To define the prevalence of psychiatric symptoms of anxiety and depression in patients at the time of their first seizure presentation to a neurologist. METHODS: Our pilot study uses a cohort approach with multimodal data (clinical, social, structural [3T magnetic resonance imaging], and functional [electroencephalogram]). We screened 105 patients referred to the Halifax First Seizure Clinic between 2014 and 2016 and 51 controls. All participants completed two screening questionnaires: Neurological Disorders Depression Inventory for Epilepsy and Generalized Anxiety Disorder 7-Item...
January 8, 2018: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://www.readbyqxmd.com/read/29307324/evaluation-of-cognition-and-cortical-excitability-in-huntington-s-disease
#5
Nitish Kamble, M Netravathi, B C Nagaraju, Abhishek Lenka, Keshav Kumar, V Sowmya, Sanjeev Jain, Pramod Kumar Pal
BACKGROUND: Recent advances in neurophysiological techniques have contributed to our understanding of the pathophysiology of Huntington's disease (HD). Studies of the motor cortical excitability and central motor pathways have shown variable results. OBJECTIVES: Our aims were to evaluate the cortical excitability changes in HD using transcranial magnetic stimulation (TMS) and correlate the changes with cognitive impairment. METHODS: The study included 32 HD patients and 30 age- and gender-matched controls...
January 8, 2018: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://www.readbyqxmd.com/read/29262877/improvement-in-severe-orthostatic-hypotension-following-carbidopa-dose-reduction
#6
Anthony C W Lau, John L Diggle, Penny P Bring
No abstract text is available yet for this article.
December 21, 2017: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://www.readbyqxmd.com/read/29251587/spinal-dural-arteriovenous-fistula-and-concomitant-intramedullary-spinal-lesion
#7
Fábio A Nascimento, Peter Kan, Lydia Sharp, Jacob J Mandel
No abstract text is available yet for this article.
December 18, 2017: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://www.readbyqxmd.com/read/29251260/clinical-profile-of-persons-with-multiple-sclerosis-across-the-continuum-of-care
#8
Luke A Turcotte, Ruth Ann Marrie, Scott B Patten, John P Hirdes
BACKGROUND: This study is part of the Innovations in Data, Evidence and Applications for Persons with Neurological Conditions project to understand the strengths, preferences, and needs of persons with neurological conditions living in Canada. OBJECTIVE: To estimate the prevalence and describe the sociodemographic and clinical characteristics of persons with multiple sclerosis in Canadian home care, nursing home, Complex Continuing Care hospitals, and inpatient mental health care settings...
December 18, 2017: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://www.readbyqxmd.com/read/29249217/palatal-tremor-revisited-disorder-with-nosological-diversity-and-etiological-heterogeneity
#9
Madhu Nagappa, Parayil S Bindu, Sanjib Sinha, Rose D Bharath, Mangalore Sandhya, Jitender Saini, Pavagada S Mathuranath, Arun B Taly
This case series aimed to describe clinicoradiological, electromyographic, and etiological spectra in palatal tremor (essential=1; symptomatic=26). Patients with symptomatic palatal tremor had 2 to 10 Hz arrhythmic electromyographic bursts, a spectrum of changes in inferior olivary nucleus, with/without lesions in Guillain Mollaret triangle, and varied etiologies (genetic=9, vascular=6, trauma=3, infections=3). Exome sequencing showed variations in POLG, WDR81, NDUFS8, TENM4, and EEF2. Clinical phenotypes of patients with POLG, WDR81, and NDUFS8 variations were consistent with that described in literature...
December 18, 2017: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://www.readbyqxmd.com/read/29249215/adult-onset-anti-n-methyl-d-aspartate-receptor-encephalitis-presenting-as-a-non-fluent-aphasia
#10
Julien Hébert, Farah El-Sadi, Catherine Maurice, Richard A Wennberg, David F Tang-Wai
No abstract text is available yet for this article.
December 18, 2017: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://www.readbyqxmd.com/read/29249210/management-and-outcomes-in-the-oldest-old-population-with-glioblastoma
#11
Fabio Y Moraes, Andrea Lo, Erin R Morgan, Barbara-Ann Millar, David B Shultz, Catherine Maurice, Craig Harlos, Paul Kongkham, Mark Bernstein, Gelareh Zadeh, Normand Laperriere, Warren Mason, Alejandro Berlin
OBJECTIVES: Glioblastoma is a lethal disease in the elderly population. We aimed to evaluate disease and treatment outcomes in the oldest-old patients. METHODS: Patients >80 years old with histologically confirmed glioblastoma treated between 2004 and 2009 were identified. We included patients managed with best supportive care (BSC), temozolomide (TMZ) alone, radiotherapy (RT) alone, or concomitantly with TMZ (CRT). Survival outcomes were analyzed using the Kaplan-Meier method...
December 18, 2017: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://www.readbyqxmd.com/read/29239294/demographics-interests-and-quality-of-life-of-canadian-neurosurgery-residents
#12
Christian Iorio-Morin, Syed Uzair Ahmed, Mark Bigder, Ayoub Dakson, Cameron Elliott, Daipayan Guha, Michelle Kameda-Smith, Pascal Lavergne, Serge Makarenko, Michael S Taccone, Michael K Tso, Bill Wang, Alexander Winkler-Schwartz, David Fortin
BACKGROUND: Neurosurgical residents face a unique combination of challenges, including long duty hours, technically challenging cases, and uncertain employment prospects. We sought to assess the demographics, interests, career goals, self-rated happiness, and overall well-being of Canadian neurosurgery residents. METHODS: A cross-sectional survey was developed and sent through the Canadian Neurosurgery Research Collaborative to every resident enrolled in a Canadian neurosurgery program as of April 1, 2016...
December 14, 2017: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://www.readbyqxmd.com/read/29237514/the-effects-of-intraoperative-sedation-on-surgical-outcomes-of-deep-brain-stimulation-surgery
#13
Jason Chui, Rizq Alimiri, Andrew Parrent, Rosemary Ann Craen
BACKGROUND: Intraoperative sedation is often used to facilitate deep brain stimulation (DBS) surgery; however, these sedative agents also suppress microelectrode recordings (MER). To date, there have been no studies that have examined the effects of differing sedatives on surgical outcomes and the success of DBS surgery. METHODS: We performed a retrospective study to evaluate the effect of differing sedative agents on postoperative surgical outcomes at 6 months in parkinsonian adult patients who underwent DBS surgery, from January 2004 through December 2014, at one academic center...
December 14, 2017: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://www.readbyqxmd.com/read/29224579/wilder-penfield-sir-arthur-currie-and-the-montreal-neurological-institute
#14
R Mark Sadler
Wilder Penfield and the Montreal Neurological Institute (MNI) are inextricably linked. It was Penfield's unique idea to create a building with an academic atmosphere wherein basic neuroscience and clinical care of neurological patients would benefit from interaction and mutual support. It is clear that without Penfield that there would be no MNI; however, the role of another Canadian icon, Sir Arthur Currie, in the development of the MNI has heretofore been barely mentioned. The thesis of this paper is that Currie had a critical role in the gestation of the MNI that has generally been ignored...
December 11, 2017: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://www.readbyqxmd.com/read/29223173/the-worried-well-characteristics-of-cognitively-normal-patients-presenting-to-a-rural-and-remote-memory-clinic
#15
Ryan Verity, Andrew Kirk, Megan E O'Connell, Chandima Karunanayake, Debra G Morgan
INTRODUCTION: In an effort to better understand why cognitively normal patients were referred to a memory clinic, we sought to identify features of "worried well" patients to better identify those more likely to be cognitively normal. METHODS: In total, 375 consecutive patients referred by primary care practitioners to a Rural and Remote Memory Clinic were categorized into two groups based on their neurologic diagnosis, "worried well" (cognitively normal, N=81) or "other" (patients with any neurologic diagnosis, N=294)...
December 10, 2017: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://www.readbyqxmd.com/read/29157319/reversible-ethyl-chloride-neurotoxicity-a-case-report
#16
Abdullah M Al-Ajmi, Mohamad A Morad, Paul E Cooper, Loqman H Hassino, Mohamed A Siddeiq
No abstract text is available yet for this article.
November 21, 2017: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://www.readbyqxmd.com/read/29157315/botulinum-toxin-type-a-injections-as-monotherapy-for-upper-limb-essential-tremor-using-kinematics
#17
Olivia Samotus, Niraj Kumar, Philippe Rizek, Mandar Jog
BACKGROUND: There is a significant need for a targeted therapy for essential tremor (ET), as medications have not been developed specifically for ET, and the ones prescribed are often not well-tolerated, so that many patients remain untreated. Recent work has shown that, unlike previous experience, kinematically guided individualized botulinum toxin type A (BoNT-A) injections provide benefit along with minimal weakness. Ours is the first long-term (96-week) safety and efficacy study of BoNT-A as monotherapy for ET using kinematically driven injection parameters...
November 21, 2017: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://www.readbyqxmd.com/read/29151389/bevacizumab-in-recurrent-high-grade-gliomas-a-canadian-retrospective-study
#18
Mary Jane Lim Fat, Catherine Maurice, Manjula Maganti, Warren P Mason
BACKGROUND: Bevacizumab has been used in recurrent glioblastoma (rGBM) since 2010 in Canada. Given its cost, potential toxicities, and unclear efficacy, further studies are required to better define suitable candidates for therapy. METHODS: A single-center retrospective review of patients started on bevacizumab for rGBM from 2012 to 2015 was performed. Patient demographics, tumor characteristics, treatment regimen, and dates of clinical progression and death were collected...
November 20, 2017: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://www.readbyqxmd.com/read/29151388/dynamic-ultrasonography-for-supinator-syndrome-a-case-report
#19
Szu-En Chen, Yi-Chian Wang
No abstract text is available yet for this article.
November 20, 2017: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://www.readbyqxmd.com/read/29145922/erdheim-chester-disease-and-palatal-tremor
#20
Natalie E Parks, R Allan Purdy
No abstract text is available yet for this article.
November 17, 2017: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
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