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Journal of the American Animal Hospital Association

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https://www.readbyqxmd.com/read/29757669/historical-prevalence-of-radiological-appendicular-osteoarthritis-in-cats-1972-1973
#1
David Godfrey, Leslie Vaughan
Interest in feline osteoarthritis has grown recently; this might be due to increased prevalence or increased awareness. This study records the presence of appendicular osteoarthritis in a subset of the United Kingdom cat population in the 1970s and estimates its prevalence. One hundred cats euthanized in 1972-1973 had a series of skeletal radiographic images taken post mortem. Each joint was put into a set with or without osteoarthritis according to the presence or absence of a specified set of radiographic features...
July 2018: Journal of the American Animal Hospital Association
https://www.readbyqxmd.com/read/29757668/a-case-of-parasitic-twinning-or-caudal-duplication-in-a-dog
#2
Janet A Grimes, Adrien-Maxence Hespel, Robert C Cole, A Ray Dillon
A 6 mo old 13.5 kg (29.7 lb) male intact American Staffordshire terrier was evaluated for a history of supernumerary pelvic limbs, with malodorous discharge from a supernumerary penis. Imaging (radiographs, abdominal ultrasound, and computed tomography with excretory urogram) showed a supernumerary pelvis with associated pelvic limbs, no osseous continuity with the primary spinal column, a colonic diverticulum extending to the supernumerary pelvis, an enlarged left kidney with a ureter connecting to a single bladder, right renal aplasia, a single descended testicle in the primary scrotum, an intra-abdominal cryptorchid testicle, and two unidentifiable soft tissue masses...
July 2018: Journal of the American Animal Hospital Association
https://www.readbyqxmd.com/read/29757667/safety-and-tolerability-of-hyperbaric-oxygen-therapy-in-cats-and-dogs
#3
Gemma L Birnie, Darren R Fry, Matthew P Best
This prospective clinical trial was designed to evaluate the safety of hyperbaric oxygen therapy (HBOT) in a population of cats and dogs with a variety of naturally occurring diseases. Seventy-eight dogs and twelve cats with various naturally occurring disease conditions, who had the potential to benefit from HBOT, were enrolled in the study. These patients were treated with HBOT in a monoplace hyperbaric oxygen chamber at 2 air pressure absolute for a treatment length of either 45 min or 60 min. There were 230 hyperbaric oxygen treatments performed during the study period...
July 2018: Journal of the American Animal Hospital Association
https://www.readbyqxmd.com/read/29757666/deslorelin-implant-treatment-for-hair-cycle-arrest-alopecia-x-in-two-intact-male-keeshonden
#4
Elizabeth A Layne, Renee V Richmond
Alopecia in dogs occurs secondary to a variety of underlying inflammatory and noninflammatory conditions. Hair cycle arrest (alopecia X) is a noninflammatory alopecia that is frustrating to diagnose and treat due to lack of understanding of disease pathogenesis. A variety of therapies for hair cycle arrest have been described with inconsistent efficacy in different dog breeds and sexes; no definitive treatment is available. This report describes the use of a deslorelin acetate implant in two sexually intact adult male keeshonden, both diagnosed with hair cycle arrest...
July 2018: Journal of the American Animal Hospital Association
https://www.readbyqxmd.com/read/29757665/comparison-of-compounded-generic-and-innovator-formulated-itraconazole-in-dogs-and-cats
#5
Janelle Renschler, Amanda Albers, Hanna Sinclair-Mackling, Lawrence Joseph Wheat
The triazole antifungal itraconazole may be cost prohibitive in brand name form; therefore, compounded and generic products are often used as alternatives. Itraconazole blood concentrations have not been studied in clinical patients receiving these formulations. Itraconazole bioassay was performed on serum/plasma from 95 dogs and 20 cats receiving itraconazole (compounded from bulk powder, generic pelletized, or brand name) for systemic mycosis treatment. Mean itraconazole concentration was lower in the compounded group (n = 42) as compared with the generic (n = 40) or brand name (n = 33) groups (0...
July 2018: Journal of the American Animal Hospital Association
https://www.readbyqxmd.com/read/29757664/reverse-saphenous-conduit-flap-in-19-dogs-and-1-cat
#6
Jacqueline V J Cavalcanti, Sabrina L Barry, Otto I Lanz, Katherine Barnes, Julia V Coutin
The purpose of this retrospective study was to report the outcomes of 19 dogs and 1 cat undergoing reverse saphenous conduit flap between 1999 and 2016. Reverse saphenous conduit flap was used to treat traumatic wounds and wounds resulting from tumor excision in the hind limb; the majority of cases had medial shearing injuries. All animals had complete flap survival. In five animals (20%), minor donor site dehiscence occurred, which did not require surgery. Other postoperative complications included signs of severe venous congestion in one dog...
July 2018: Journal of the American Animal Hospital Association
https://www.readbyqxmd.com/read/29757663/bicipital-tendinopathy-and-carpal-valgus-following-a-distant-direct-thoracoabdominal-skin-flap-in-a-german-shepherd-with-necrotizing-fasciitis
#7
Benjamin Mielke, Nicola Kulendra, Zoe Halfacree, Elvin Kulendra
A 4 mo old German shepherd dog was presented following an acute onset lameness and swelling of the thoracic limb. Clinical signs, surgical findings, and culture results were consistent with a diagnosis of necrotizing fasciitis. Initial management consisted of extensive surgical debridement, wound lavage, and bandaging. Surgical closure was achieved with an axillary fold flap and distant direct single-pedicle thoracoabdominal flap. Three mo later, following deterioration of the lameness that was associated with carpal valgus, carpal subluxation, and tendinopathy of the distal radial insertion of the biceps brachii tendon, a closing wedge pancarpal arthrodesis and tenotomy of the biceps brachii tendon was performed...
July 2018: Journal of the American Animal Hospital Association
https://www.readbyqxmd.com/read/29757662/a-review-of-the-surgical-management-of-perineal-hernias-in-dogs
#8
Sukhjit Singh Gill, Robert D Barstad
Perineal hernia refers to the failure of the muscular pelvic diaphragm to support the rectal wall, resulting in herniation of pelvic and, occasionally, abdominal viscera into the subcutaneous perineal region. The proposed causes of pelvic diaphragm weakness include tenesmus associated with chronic prostatic disease or constipation, myopathy, rectal abnormalities, and gonadal hormonal imbalances. The most common presentation of perineal hernia in dogs is a unilateral or bilateral nonpainful swelling of the perineum...
July 2018: Journal of the American Animal Hospital Association
https://www.readbyqxmd.com/read/29757661/a-pivotal-field-study-to-support-the-registration-of-levothyroxine-sodium-tablets-for-canine-hypothyroidism
#9
Victoria A Lewis, Carla M K Morrow, Johnny A Jacobsen, W Eugene Lloyd
A prospective, pivotal, multicenter field study to evaluate the dose regimen, effectiveness, and safety of levothyroxine sodium tablets, USP for the treatment of hypothyroidism and hypothyroidism-associated clinical signs in dogs was conducted. Ninety-two dogs diagnosed with primary hypothyroidism met the entrance criteria and were enrolled into the study. Levothyroxine sodium was administered to each dog on a daily basis either as the whole dose q 24 hr or as half the dose q 12 hr. Dosing started at 0.1 mg/10 lb (0...
July 2018: Journal of the American Animal Hospital Association
https://www.readbyqxmd.com/read/29558220/mri-findings-of-suprasellar-germ-cell-tumors-in-two-dogs
#10
Laurie Cook, Michelle Tensley, Wm Tod Drost, Christopher Koivisto, Michael Oglesbee
A 4 yr old border collie presenting for mydriasis and decreased mentation and a 7 yr old Boston terrier presenting for obtundation, head tilt, and paraparesis were both evaluated using MRI. Findings in both included mass lesions of the thalamus and brainstem that were hypo- to isointense on T1-weighted images and hyperintense on T2-weighted images with regions of hypointensity, and robust contrast enhancement and displacement of adjacent structures. Postmortem histopathology findings, tumor location, and a mixed pattern of epithelial cell differentiation were consistent with germ cell tumor in both cases...
May 2018: Journal of the American Animal Hospital Association
https://www.readbyqxmd.com/read/29558219/azotemia-and-proteinuria-in-dogs-infected-with-babesia-gibsoni
#11
Tarini Ullal, Adam Birkenheuer, Shelly Vaden
Babesiosis is a hemoprotozoal tick-borne disease that is commonly associated with thrombocytopenia and anemia; however, renal involvement has been documented in dogs. The purpose of this retrospective study was to document azotemia and proteinuria in dogs infected with Babesia sp. and to describe the response to antiprotozoal therapy. The electronic database of the North Carolina State University Vector Borne Disease Laboratory was searched to identify dogs who were diagnosed with babesiosis and to determine if they had proteinuria and/or azotemia...
May 2018: Journal of the American Animal Hospital Association
https://www.readbyqxmd.com/read/29558218/correlation-between-body-weight-and-mitoxantrone-associated-neutropenia-in-dogs
#12
Danielle Richardson, Valerie J Poirier, Arata Matsuyama, Jerome Calvalido
Thirty-seven dogs with histologically or cytologically confirmed malignant tumors treated with single-agent mitoxantrone at 5 mg/m2 were evaluated in a retrospective study assessing the correlation between body weight and neutropenia associated with a single dose of mitoxantrone in dogs. Overall, eight dogs (21%) experienced grade 3 neutropenia and five dogs (14%) experienced grade 4 neutropenia on day 7 following mitoxantrone chemotherapy. Dogs ≤10 kg body weight were significantly more likely to develop grade 3 or 4 neutropenia (5...
May 2018: Journal of the American Animal Hospital Association
https://www.readbyqxmd.com/read/29558217/combination-chlorambucil-firocoxib-or-chlorambucil-prednisolone-treatment-for-inflammatory-colorectal-polyps-in-miniature-dachshunds
#13
Akira Murakami, Ayami Shibahashi, Ryota Iwasaki, Mifumi Kawabe, Mami Murakami, Hiroki Sakai, Takashi Mori
Inflammatory colorectal polyps (ICRP), which are more commonly recognized in miniature dachshunds, are thought to represent an immune-mediated disease. This retrospective case series describes six miniature dachshunds with refractory ICRP, who were treated with chlorambucil (CLB) combined with firocoxib or prednisolone. Improvement in clinical manifestations was seen in five of the six dogs by the end of the study period; four were treated with CLB/firocoxib and one with CLB/prednisolone. One dog had nonregenerative anemia after 23 mo of treatment with CLB, but whether there was a causative relationship was unclear...
May 2018: Journal of the American Animal Hospital Association
https://www.readbyqxmd.com/read/29558216/fanconi-syndrome-in-irish-wolfhound-siblings
#14
Nick X Bommer, Serena E Brownlie, Linda R Morrison, Marge L Chandler, James W Simpson
Three juvenile male Irish wolfhound littermates presented with marked polyuria and polydipsia. The four female siblings were apparently unaffected. Diagnostic testing revealed glucosuria with normoglycemia, generalized aminoaciduria, hypokalemia and metabolic acidosis consistent with Fanconi syndrome. Renal ultrasonographic and histologic findings are presented. Cases were managed with a supplementation regimen based on a treatment protocol for Fanconi syndrome in basenjis. These dogs did not have angular limb deformities as documented previously in juvenile canine siblings with Fanconi syndrome...
May 2018: Journal of the American Animal Hospital Association
https://www.readbyqxmd.com/read/29558215/the-effect-of-a-hydrocolloid-dressing-on-second-intention-wound-healing-in-cats
#15
Vassiliki Tsioli, Pagona G Gouletsou, Apostolos D Galatos, Dimitra Psalla, Antonios Lymperis, Aikaterini I Sideri, Lyssimachos G Papazoglou
The objective of the present study was to evaluate the effect of a hydrocolloid dressing on second intention wound healing in cats. Two full-thickness skin wounds, measuring 2 × 2 cm, were created on both sides of the dorsal midline of 10 cats; bilaterally, one randomly selected wound was bandaged with a hydrocolloid dressing and the second one (control) with a semiocclusive pad. Subjective clinical evaluation of granulation tissue formation, of the quantity and nature of wound exudate, and planimetry were performed on the right-side wounds, and histological examination on the left...
May 2018: Journal of the American Animal Hospital Association
https://www.readbyqxmd.com/read/29558214/preliminary-assessment-of-a-novel-14-day-electrocardiographic-adhesive-patch-monitor-in-dogs
#16
Jonathan Lichtenberger, Kathryn M Meurs, Etienne Côté
Cardiac arrhythmias often are transient and might not be detected using conventional electrocardiographic (ECG) techniques. The adhesive patch monitor (APM) is a single-lead, lightweight, up to 14-day continuous ambulatory ECG monitor. This study aimed to prospectively assess its usability in four boxer dogs considered either to be healthy or to have arrhythmogenic right ventricular cardiomyopathy. Optimal recording was obtained by placing the APM on the left side of the animal's thorax, at the fifth intercostal space, slightly dorsal to the costochondral junction, and oriented either vertically or parallel to the long axis of the heart...
May 2018: Journal of the American Animal Hospital Association
https://www.readbyqxmd.com/read/29558213/oral-fluid-thiol-detection-test-identifies-underlying-active-periodontal-disease-not-detected-by-the-visual-awake-examination
#17
Katherine E Queck, Angela Chapman, Leslie J Herzog, Tamara Shell-Martin, Anthony Burgess-Cassler, George David McClure
Periodontal disease in dogs is highly prevalent but can only be accurately diagnosed by performing an anesthetized oral examination with periodontal probing and dental radiography. In this study, 114 dogs had a visual awake examination of the oral cavity and were administered an oral-fluid thiol-detection test prior to undergoing a a full-mouth anesthetized oral examination and digital dental radiographs. The results show the visual awake examination underestimated the presence and severity of active periodontal disease...
May 2018: Journal of the American Animal Hospital Association
https://www.readbyqxmd.com/read/29558212/combination-of-bleomycin-and-cytosine-arabinoside-chemotherapy-for-relapsed-canine-lymphoma
#18
Karen Batschinski, Nikolaos Dervisis, Barbara Kitchell, Rebecca Newman, Todd Erfourth
A retrospective study was performed to evaluate response rate, time to progression, and toxicity of a bleomycin and cytosine arabinoside (Bleo/Cytarabine) combination protocol for dogs with relapsed lymphoma (LSA). Dogs diagnosed with LSA and previously treated with chemotherapy were included in the study. A total of 20 dogs met the inclusion criteria, and 19 were evaluable for response. Bleomycin was administered subcutaneously on days 1 and 8 and cytosine arabinoside was administered subcutaneously on days 1-5 of a 21-day cycle...
May 2018: Journal of the American Animal Hospital Association
https://www.readbyqxmd.com/read/29372871/clinical-features-of-english-bulldogs-with-presumed-arrhythmogenic-right-ventricular-cardiomyopathy-31-cases-2001-2013
#19
Suzanne M Cunningham, Joseph T Sweeney, John MacGregor, Bruce A Barton, John E Rush
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an important cause of sudden death in people and boxer dogs that has recently been described in English bulldogs. The objective of this retrospective study was to describe the clinical characteristics of English bulldogs with presumed ARVC. The medical records were searched for English bulldogs examined between 2001 and 2013 with a clinical diagnosis of ARVC. The average age of the 31 dogs identified was 9.2 ± 1.6 yr (range 7-13 yr). Males were overrepresented by a factor of 2...
March 2018: Journal of the American Animal Hospital Association
https://www.readbyqxmd.com/read/29372870/stereotactic-volume-modulated-arc-radiotherapy-in-canine-meningiomas-imaging-based-and-clinical-neurological-posttreatment-evaluation
#20
Mario Dolera, Luca Malfassi, Simone Pavesi, Silvia Marcarini, Massimo Sala, Giovanni Mazza, Nancy Carrara, Sara Finesso, Gaetano Urso
A prospective study to assess high-dose hypofractionated volume modulated arc radiotherapy feasibility and efficacy in canine meningiomas was conducted. Thirty-nine patients with encephalic and spinal meningiomas assumed from MRI findings were recruited and received high-dose hypofractionated volumetric modulated arc radiotherapy by a linear accelerator equipped with an external beam modulator micro-multileaf collimator and an XVI cone beam computed tomography system. The prescribed mean dose was 33 Gy in five fractions...
March 2018: Journal of the American Animal Hospital Association
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