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Journal of the American Animal Hospital Association

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https://www.readbyqxmd.com/read/28892429/adjuvant-doxorubicin-with-or-without-metronomic-cyclophosphamide-for-canine-splenic-hemangiosarcoma
#1
Arata Matsuyama, Valerie J Poirier, Fernanda Mantovani, Robert A Foster, Anthony J Mutsaers
This retrospective study investigated the outcome of 33 dogs with splenic hemangiosarcoma treated with surgery followed by adjuvant dose-intensified doxorubicin (DOX) with or without low-dose metronomic cyclophosphamide (LDM-C) maintenance therapy. Among the 33 dogs, 18 dogs received LDM-C. Clinical stage was available for all dogs (5 stage I, 18 stage II, and 10 stage III). Nine dogs had macroscopic, and 24 dogs had microscopic disease at the start of DOX treatment. Median progression-free survival (PFS) and overall survival were 125 and 133 days, respectively...
September 11, 2017: Journal of the American Animal Hospital Association
https://www.readbyqxmd.com/read/28892428/successful-surgical-correction-of-a-mesenteric-volvulus-with-concurrent-foreign-body-obstruction-in-two-puppies
#2
Susan Jones, Steven G Friedenberg, Jason Callard, Leslie Abernathy, Julien Guillaumin
A 9 mo old female intact English mastiff (case 1) presented for anorexia and vomiting for 7 days. A 7 mo old male castrated American bulldog (case 2) presented for vomiting and anorexia for 2 days without diarrhea. Both dogs were diagnosed with mesenteric volvulus based on exploratory laparotomy, which also revealed an intestinal foreign body obstruction. Case 1 required critical care support during recovery but was ultimately discharged, whereas case 2 had an uncomplicated recovery. Both were reported to be back to normal 1 wk after surgery...
September 11, 2017: Journal of the American Animal Hospital Association
https://www.readbyqxmd.com/read/28892427/norwegian-or-crusted-sarcoptic-mange-in-two-leishmanial-dogs
#3
Flora Kaltsogianni, Rania Farmaki, Alexander F Koutinas
Norwegian or crusted scabies (N/CS) is a rare skin disease with very few cases reported in the dog or the cat. Two adult, stray dogs were admitted in our clinic with a generalized, multifocal to diffuse and nonpruritic dermatitis that was characterized by severe crusting, scaling, and ulceration. In both instances, leishmaniosis and N/CS were diagnosed by immunofluorescent antibody test serology, lymph node cytology, and skin scrapings in which high numbers of Sarcoptes mites were found. The combination of miticidal and antileishmanial treatment, supported by topical treatment and nutritional support, resulted in the complete resolution of the skin lesions and spectacular improvement of the body condition in both cases...
September 11, 2017: Journal of the American Animal Hospital Association
https://www.readbyqxmd.com/read/28892426/agreement-of-axillary-and-auricular-temperature-with-rectal-temperature-in-systemically-healthy-dogs-undergoing-surgery
#4
Brandy Cichocki, Danielle Dugat, Mark Payton
Obtaining a patient's temperature is an important part of a patient's physical examination. As human medicine transitions to noninvasive temperature measurements, so does veterinary medicine. Historically, temperature measurement has been obtained from rectal readings; however, alternative methods, such as axillary and auricular temperatures, are increasing in popularity. The purpose of the study was to compare these alternative techniques to the gold standard of rectal temperature. Temperatures were obtained three ways for each patient: rectal, axillary, and auricular...
September 11, 2017: Journal of the American Animal Hospital Association
https://www.readbyqxmd.com/read/28892425/laparoscopic-resection-of-a-pancreatic-%C3%AE-cell-tumor-in-a-dog
#5
Janet Kovak Mcclaran, Philippa Pavia, Anthony J Fischetti, Taryn A Donovan
Laparoscopic partial pancreatectomy has been performed in experimental canine studies and has been evaluated in human medicine but has not been reported in a clinical veterinary case. The authors present a 9 yr old field spaniel with weakness and hypoglycemia with insulin levels and Amended Insulin: Glucose Ratio results equivocal for a pancreatic insulinoma. Multiple abdominal ultrasounds did not detect the tumor, yet dual-phase computed tomographic angiography revealed the presence of a focal hypoattenuating nodule in the left lobe of the pancreas...
September 11, 2017: Journal of the American Animal Hospital Association
https://www.readbyqxmd.com/read/28892424/an-unusual-case-of-portal-hypertension-secondary-to-primary-hypoplasia-of-the-portal-vein
#6
Lauren Harris, Miryam Reems, Sharon Dial
Primary hypoplasia of the portal vein with secondary portal hypertension and acquired portosystemic collateral circulation is infrequently reported in the veterinary literature. Diagnosis of this condition requires documentation of abnormal hepatocellular function, the lack of intrahepatic or extrahepatic macroscopic congenital portosystemic shunts, and liver histopathology demonstrating portal hypoperfusion in the absence of hepatic inflammation or nodular regeneration. Due to a perceived poor prognosis, many patients with this condition are euthanized; however, those that are spared can be medically managed, in some cases for years...
September 11, 2017: Journal of the American Animal Hospital Association
https://www.readbyqxmd.com/read/28892423/gastric-dilatation-associated-with-gastric-colonization-with-sarcina-like-bacteria-in-a-cat-with-chronic-enteritis
#7
Joon Young Im, Set Sokol, Gerald E Duhamel
An 11 yr old spayed female domestic longhair cat was presented for an acute onset of vomiting. Abdominal radiographs and ultrasound revealed severe gastric dilatation (GD) without evidence of gastric outflow obstruction. On esophagogastroduodenoscopy, the duodenal mucosa was mildly erythematous, and a moderate, diffuse, chronic enteritis was found by histological examination of duodenal biopsies. Large numbers of Sarcina-like bacteria without associated inflammation were present in gastric mucosal biopsies...
September 11, 2017: Journal of the American Animal Hospital Association
https://www.readbyqxmd.com/read/28892422/clinicopathologic-and-microbiologic-findings-associated-with-emphysematous-cystitis-in-27-dogs
#8
Lindsay Kate Merkel, Jody Lulich, David Polzin, Christopher Ober, Jodi Westropp, Jane Sykes
This is a retrospective case series of 27 dogs with emphysematous cystitis. Medical records from two veterinary teaching hospitals from 1992 to 2014 were reviewed. The aims of the study were to determine imaging findings, common underlying disease processes, and prevalent bacterial species and their antimicrobial susceptibility patterns in dogs with emphysematous cystitis. The most common lower urinary tract sign was hematuria. Gas was detected in the wall and lumen of the urinary bladder in 14 of 27 dogs (51...
September 11, 2017: Journal of the American Animal Hospital Association
https://www.readbyqxmd.com/read/28792799/investigating-associations-between-proliferation-indices-c-kit-and-lymph-node-stage-in-canine-mast-cell-tumors
#9
Erika Lauren Krick, Matti Kiupel, Amy C Durham, Tuddow Thaiwong, Dorothy C Brown, Karin U Sorenmo
Previous studies have evaluated cellular proliferation indices, KIT expression, and c-kit mutations to predict the clinical behavior of canine mast cell tumors (MCTs). The study purpose was to retrospectively compare mitotic index, argyrophilic nucleolar organizer regions (AgNORs)/nucleus, Ki-67 index, KIT labeling pattern, and internal tandem duplication mutations in c-KIT between stage I and stage II grade II MCTs. Medical records and tumor biopsy samples from dogs with Grade II MCTs with cytological or histopathological regional lymph node evaluation were included...
August 9, 2017: Journal of the American Animal Hospital Association
https://www.readbyqxmd.com/read/28792798/cholecystopexy-and-pericardial-pseudocyst-removal-in-a-dog-with-a-congenital-peritoneopericardial-diaphragmatic-hernia
#10
Quentin Cabon, Eric Norman Carmel, Julien Cabassu
A 4 mo old spayed female golden retriever was presented with a peritoneopericardial diaphragmatic hernia (PPDH) that was diagnosed during neutering. Echocardiography revealed a fluid-filled structure and parts of the liver in the pericardial cavity. Computed tomography confirmed the existence of the PPDH and the herniation of the right medial liver lobe and the gallbladder. Cystic masses were observed in the pericardial and the peritoneal cavities, possibly communicating through the PPDH. A median laparotomy revealed a single lobulated cystic lesion extending into both the pericardial and peritoneal cavities through the PPDH...
August 9, 2017: Journal of the American Animal Hospital Association
https://www.readbyqxmd.com/read/28792797/magnetic-resonance-imaging-and-clinical-findings-associated-with-choroid-plexus-spinal-cord-drop-metastases
#11
Carmen L Yeamans, Rodrigo Gutierrez-Quintana, Allison Haley, Catherine G Lamm
A 5 yr old castrated male whippet presented with a unique presentation of ambulatory paraparesis and subsequent diagnosis of primary intracranial choroid plexus carcinoma, with metastases to the cervical, thoracic, lumbar, and sacral spinal cord segments. Magnetic resonance imaging was performed initially of the thoracolumbar vertebral column and was followed by MRI sequences of the brain for confirmation of the presence of a primary intracranial tumor. The dog was euthanized immediately following diagnostic imaging due to the severity of clinical signs and poor prognosis...
August 9, 2017: Journal of the American Animal Hospital Association
https://www.readbyqxmd.com/read/28792796/clinical-response-and-side-effects-associated-with-testosterone-cypionate-for-urinary-incontinence-in-male-dogs
#12
Jean-S├ębastien Palerme, Allison Mazepa, Rae G Hutchins, Vincent Ziglioli, Shelly L Vaden
Urethral sphincter mechanism incompetence (USMI) is reported much more seldom in male dogs than in female dogs. The few existing reports evaluating the efficacy of medical therapy in controlling USMI in males have demonstrated limited success. In this case series, we report the effect of testosterone cypionate, given at a median dose of 1.5 mg/kg intramuscularly every 4 wk, in eight male dogs with USMI. Response was evaluated through the review of medical records and telephone interviews with the clients. Based on owners' assessments, a good to excellent response was reported in three of eight dogs (38%), a slight response was reported in one of eight dogs (12%), and a poor response was reported in four of eight dogs (50%)...
August 9, 2017: Journal of the American Animal Hospital Association
https://www.readbyqxmd.com/read/28792795/diphallia-in-a-mixed-breed-puppy-case-report
#13
Rebecca Laube, Alysa Cook, Kevin Winkler
An 8 mo old intact male mixed-breed dog presented for diphallia with paraphimosis of the nonfunctional, accessory penis. Bloodwork, an abdominal ultrasound, and a positive contrast retrograde urethrogram were performed and revealed no other structural abnormalities. Surgical excision of the accessory penis was elected. This is one of three reported cases of diphallia in the dog in the English literature, but this is the only case in which no other congenital abnormalities were identified. The authors also review diphallia in both the veterinary and human literature...
August 9, 2017: Journal of the American Animal Hospital Association
https://www.readbyqxmd.com/read/28792794/squamous-cell-carcinoma-of-the-penis-with-pulmonary-metastasis-and-paraneoplastic-hypertrophic-osteopathy-in-a-dog
#14
Victoria Jenkins, Carlos Henrique de Mello Souza, Louis-Phillippe de Lorimier, Evandro de Toledo-Piza
Squamous cell carcinoma of the penis was diagnosed by incisional biopsy of a penile mass in a 12 yr old intact male beagle dog presenting with hemorrhagic discharge from the prepuce. Penile amputation, orchiectomy with scrotal ablation, and scrotal urethrostomy were performed. Hypertrophic osteopathy secondary to pulmonary metastatic disease occurred 10 mo after the surgery. Palliative treatment with piroxicam was administered and led to complete resolution of the clinical signs of the pain. Sixteen months following surgery, the dog presented with significant dyspnea and anorexia and was euthanized due to poor prognosis...
August 9, 2017: Journal of the American Animal Hospital Association
https://www.readbyqxmd.com/read/28792793/effect-of-cricoarytenoid-joint-preservation-and-suture-tension-on-arytenoid-lateralization
#15
Elizabeth Davis, Brenda Salinardi, Jason Spina, Claire Sharp
The objective of this experimental study was to evaluate the effects of cricoarytenoid (CA) joint preservation versus disarticulation on rima glottidis (RG) area with the epiglottis open and closed under both low and high suture tension. Canine cadaver larynges were used. A unilateral arytenoid lateralization (UAL) was performed with low or high suture tension and with the CA joint preserved or disarticulated. Rima glottidis area was measured with the epiglottis in an open and closed position. Results indicated that RG area was increased over baseline when UAL was performed with both low and high suture tension when the epiglottis was in an open position...
August 9, 2017: Journal of the American Animal Hospital Association
https://www.readbyqxmd.com/read/28846453/2017-aaha-canine-vaccination-guidelines
#16
Richard B Ford, Laurie J Larson, Kent D McClure, Ronald D Schultz, Link V Welborn
No abstract text is available yet for this article.
September 2017: Journal of the American Animal Hospital Association
https://www.readbyqxmd.com/read/28535138/paramedian-submandibular-approach-for-removal-of-foreign-bodies-in-the-pterygoid-muscle-in-two-dogs
#17
Elizabeth Gettinger, Daniel Smeak, Angela Marolf
The purpose of this report is to document a unique location of an oropharyngeal foreign body, diagnosed via contrast computed tomography (CT), as well as a novel surgical approach to the pterygoid muscle region. Oropharyngeal foreign objects are an uncommon but potentially serious disease that can lead to chronic abscessation and pain. Two dogs were presented with chronic complaints, including pain and inability to fully open the mouth for a 1 yr and 5 mo duration, respectively. There was no history or evidence of skin sinus or submandibular/cervical swelling on physical examination of either dog...
July 2017: Journal of the American Animal Hospital Association
https://www.readbyqxmd.com/read/28535137/the-effect-of-heart-disease-on-anesthetic-complications-during-routine-dental-procedures-in-dogs
#18
Jennifer E Carter, Alison A Motsinger-Reif, William V Krug, Bruce W Keene
Dental procedures are a common reason for general anesthesia, and there is widespread concern among veterinarians that heart disease increases the occurrence of anesthetic complications. Anxiety about anesthetizing dogs with heart disease is a common cause of referral to specialty centers. To begin to address the potential effect of heart disease on anesthetic complications in dogs undergoing anesthesia for routine dental procedures, we compared anesthetic complications in 100 dogs with heart disease severe enough to trigger referral to a specialty center (cases) to those found in 100 dogs without cardiac disease (controls) that underwent similar procedures at the same teaching hospital...
July 2017: Journal of the American Animal Hospital Association
https://www.readbyqxmd.com/read/28535136/eosinophilic-esophagitis-in-a-kitten
#19
Julie Pera, Douglas Palma, Taryn A Donovan
A 4 mo old intact male kitten was presented for chronic regurgitation and failure to thrive after weaning to dry food. Esophageal dilatation and severe diffuse proliferative lesions of the esophageal mucosa were found via radiography and esophagoscopy, respectively. Histopathologic examination revealed severe, chronic, diffuse, hyperplastic eosinophilic and mastocytic esophagitis. Eosinophilic infiltrates were prominent, with a mean of 29.8 eosinophils per high power field, supportive of eosinophilic esophagitis (EoE)...
July 2017: Journal of the American Animal Hospital Association
https://www.readbyqxmd.com/read/28535135/recovery-from-cyclophosphamide-overdose-in-a-dog
#20
Jessica Renee Finlay, Kenneth Wyatt, Courtney North
An adult female spayed dog was evaluated after inadvertently receiving a total dose of 1,750 mg oral cyclophosphamide, equivalent to 2,303 mg/m(2), over 21 days (days -21 to 0). Nine days after the last dose of cyclophosphamide (day +9), the dog was evaluated at Perth Veterinary Specialists. Physical examination revealed mucosal pallor, a grade 2/6 systolic heart murmur, and severe hemorrhagic cystitis. Severe nonregenerative pancytopenia was detected on hematology. Broad spectrum antibiotics, two fresh whole blood transfusions, granulocyte colony stimulating factor, and tranexamic acid were administered...
July 2017: Journal of the American Animal Hospital Association
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