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Yonago Acta Medica

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https://www.readbyqxmd.com/read/28701897/usefulness-of-pulse-oximeter-that-can-measure-spo2-to-one-digit-after-decimal-point
#1
Akihiro Yamamoto, Naoto Burioka, Aritoshi Eto, Takashi Amisaki, Eiji Shimizu
Pulse oximeters are used to noninvasively measure oxygen saturation in arterial blood (SaO2). Although arterial oxygen saturation measured by pulse oximeter (SpO2) is usually indicated in 1% increments, the value of SaO2 from arterial blood gas analysis is not an integer. We have developed a new pulse oximeter that can measure SpO2 to one digit after the decimal point. The values of SpO2 from the newly developed pulse oximeter are highly correlated with the values of SaO2 from arterial blood gas analysis (SpO2 = 0...
June 2017: Yonago Acta Medica
https://www.readbyqxmd.com/read/28701896/use-of-body-mass-index-to-predict-the-prognosis-of-patients-with-remnant-gastric-cancer
#2
Tomoyuki Matsunaga, Hiroaki Saito, Tomohiro Osaki, Yusuke Kono, Yuki Murakami, Hirohiko Kuroda, Yoji Fukumoto, Yoshiyuki Fujiwara
BACKGROUND: Remnant gastric cancer (RGC) is an uncommon form of gastric cancer. The aim of this study was to investigate factors influencing the prognosis of patients with RGC. METHODS: A total of 49 patients diagnosed with RGC and 214 patients with primary upper third gastric cancer (PUGC) at our institution between January 1990 and December 2014 were included. The clinicopathological characteristics, prognosis, and factors influencing prognosis were compared. RESULTS: The body mass index (BMI) of RGC was significantly lower than that for PUGC (P < 0...
June 2017: Yonago Acta Medica
https://www.readbyqxmd.com/read/28701895/decreased-serum-concentration-of-total-igg-is-related-to-tumor-progression-in-gastric-cancer-patients
#3
Hiroaki Saito, Kozo Miyatani, Yusuke Kono, Yuki Murakami, Hirohiko Kuroda, Tomoyuki Matsunaga, Yoji Fukumoto, Shuichi Takano, Tomohiro Osaki, Yoshiyuki Fujiwara
BACKGROUND: There is accumulating evidence that shows cell-mediated immunity regulated by T cells is impaired in cancer patients. Unfortunately, the mechanisms by which B cells participate in tumor immunity are only partially understood. METHODS: The serum concentration of Immunoglobulin G (IgG) was measured by Enzyme-Linked ImmunoSorbent Assay (ELISA) in patients with gastric cancer. Immunohistochemistry was also performed using the anti- cluster of differentiation (CD)134 antibody to evaluate the number of plasma cells in the tumor tissue...
June 2017: Yonago Acta Medica
https://www.readbyqxmd.com/read/28701894/volume-measurement-by-diffusion-weighted-imaging-in-cervical-cancer
#4
Shinya Fujii, Naoki Iwata, Chie Inoue, Naoko Mukuda, Takeru Fukunaga, Toshihide Ogawa
BACKGROUND: The aim of this paper was to evaluate the validity of tumor volume measurement using diffusion-weighted (DW) imaging in cervical cancer. METHODS: In this retrospective study, 22 patients, who underwent preoperative 3.0 T MR examinations with DW imaging were evaluated. Tumor volume measurement by oblique axial (short axis to the uterine cervix) T2-weighted imaging was performed by manually outlining the tumor on the monitor. The area of tumor in each slice was multiplied by the slice profile (slice thickness plus intersection gap), and the total tumor volume was calculated by summation of these obtained volumes...
June 2017: Yonago Acta Medica
https://www.readbyqxmd.com/read/28701893/risk-assessment-of-hepatocellular-carcinoma-in-general-population-by-liver-stiffness-in-combination-with-controlled-attenuation-parameter-using-transient-elastography-a-cross-sectional-study
#5
Takaaki Sugihara, Masahiko Koda, Tomomitsu Matono, Kinya Okamoto, Yoshikazu Murawaki, Hajime Isomoto, Shiho Tokunaga
BACKGROUND: Hepatocellular carcinoma (HCC) in patients without hepatitis B (HBV) and -C virus (HCV) infection are increasing in Japan. Method for detecting high-risk liver diseases of HCC in general population has still not been established. Liver stiffness measurement (LSM) and Controlled Attenuation Parameter (CAP) using transient elastography (TE; FibroScan System) are useful for detecting liver fibrosis and steatosis. The aim of this study is to clarify TE for risk assessment of HCC in general population...
June 2017: Yonago Acta Medica
https://www.readbyqxmd.com/read/28701892/a-pilot-study-of-post-operative-adjuvant-vaccine-for-advanced-gastric-cancer
#6
Yoshiyuki Fujiwara, Keijiro Sugimura, Hiroshi Miyata, Takeshi Omori, Hiroyuki Nakano, Chie Mochizuki, Katsuji Shimizu, Hiroaki Saito, Keigo Ashida, Soichiro Honjyo, Yusuke Nakamura, Masahiko Yano
BACKGROUND: Previously, we had performed a clinical study using human leukocyte antigen (HLA)-A24-binding peptide vaccines containing a combination of novel cancer-testis antigens and anti-angiogenic peptides derived from DEPDC1, URLC10, FOXM1, KIF20A and VEGFR1 for advanced gastric cancer (AGC) patients who were refractory to chemotherapy. We applied the cocktail vaccine to the combination therapy with S-1 for patients with AGC as a post-operative adjuvant therapy and performed this clinical pilot study...
June 2017: Yonago Acta Medica
https://www.readbyqxmd.com/read/28701891/comprehensive-analysis-of-factors-affecting-post-partial-nephrectomy-renal-global-function
#7
Takehiro Sejima, Tetsuya Yumioka, Noriya Yamaguchi, Hideto Iwamoto, Toshihiko Masago, Shuichi Morizane, Masashi Honda, Atsushi Takenaka
BACKGROUND: To explore new factors that are predictive of post-partial nephrectomy (PN) renal global function, we analyzed various clinico-pathological factors with a special focus on renal volume measured via three-dimensional imaging technology and histopathological parameters in non-neoplastic parenchyma. METHODS: Estimated glomerular filtration rate (eGFR) and computed tomography (CT) scan were examined pre- and 6 months. post-operatively in 52 patients treated by PN...
June 2017: Yonago Acta Medica
https://www.readbyqxmd.com/read/28701890/relationship-between-oxidative-stress-physical-activity-and-vitamin-intake-in-patients-with-asthma
#8
Akira Yamasaki, Yuji Kawasaki, Kenichi Takeda, Tomoya Harada, Yasuyuki Hasegawa, Takehito Fukushima, Ryota Okazaki, Haruhiko Makino, Yoshihiro Funaki, Yuriko Sueda, Akihiro Yamamoto, Jun Kurai, Masanari Watanabe, Eiji Shimizu
BACKGROUND: Oxidative stress plays an important role in the pathogenesis of bronchial asthma. Antioxidant nutrition and supplementation have been used to reduce oxidative stress. However, a clinical trial with antioxidant supplementation showed no beneficial effects in patients with asthma. On the other hand, physical activity is related to the prognosis of chronic obstructive pulmonary disease (COPD) and is also related to oxidant status. We investigated the relationships between oxidative stress, serum levels of vitamins, dietary vitamin intake, daily activities, and pulmonary functions in patients with asthma...
June 2017: Yonago Acta Medica
https://www.readbyqxmd.com/read/28701889/education-for-community-based-family-medicine-a-social-need-in-the-real-world
#9
REVIEW
Shin-Ichi Taniguchi, Daeho Park, Kazuoki Inoue, Toshihiro Hamada
One of the most critical social problems in Japan is the remarkable increase in the aging population. Elderly patients with a variety of complications and issues other than biomedical problems such as dementia and life support with nursing care have been also increasing. Ever since the Japanese economy started to decline after the economic bubble burst of 1991 and the Lehman Brothers bankruptcy in 2008, how we can resolve health problems of the elderly at a lower cost has become one of our most challenging social issues...
June 2017: Yonago Acta Medica
https://www.readbyqxmd.com/read/28701888/pharmacological-treatment-of-heart-failure-with-preserved-ejection-fraction
#10
REVIEW
Kazuhiro Yamamoto
Heart failure with preserved ejection fraction is a socioeconomic burden in Japan as well as other developed countries. Diuretics are widely used to attenuate symptoms and signs of congestion in both heart failure with preserved and reduced ejection fraction, although their effects on long-term prognosis of both phenotypes of heart failure have not been demonstrated because of an ethical difficulty in designing a randomized and prospective clinical trial. Guidelines do not provide any guidance on therapy choice, and physicians blindly choose furosemide among loop diuretics in current clinical settings...
June 2017: Yonago Acta Medica
https://www.readbyqxmd.com/read/28331426/environmental-distribution-and-drug-susceptibility-of-achromobacter-xylosoxidans-isolated-from-outdoor-and-indoor-environments
#11
Sachiko Nakamoto, Misaki Sakamoto, Kana Sugimura, Yuki Honmura, Yuki Yamamoto, Natsumi Goda, Hiroo Tamaki, Naoto Burioka
Achromobacter xylosoxidans is an environmental bacterium with multi-drug resistance. We isolated Achromobacter xylosoxidans and investigated its susceptibility to 13 drugs. Seventy-eight water samples were collected from rivers and ponds, and 11 samples were swabbed from residential sinks and baths. Nine strains of Achromobacter xylosoxidans were isolated from the 89 samples. Five strains, including 2 that were sampled from residential homes, showed high resistance to multiple aminoglycosides. This indicated that Achromobacter xylosoxidans is widely distributed in various outdoor and indoor environments...
March 2017: Yonago Acta Medica
https://www.readbyqxmd.com/read/28331425/apocrine-adenocarcinoma-occurring-on-the-chin
#12
Hiromi Higaki-Mori, Kazunari Sugita, Reiko Tsutsumi, Koji Adachi, Yuichi Yoshida, Osamu Yamamoto
We report a case of adenocarcinoma affecting the chin of a 48-year-old man. The tumor showed signs of apocrine differentiation and had infiltrated the muscle. The patient had no history or clinical evidence of breast cancer. We made a diagnosis of cutaneous apocrine adenocarcinoma. Apocrine adenocarcinoma rarely arises in areas with scarce apocrine glands. We reviewed the literature on apocrine adenocarcinoma of the face in areas other than the eyelids and auditory canal, where specialized apocrine glands are present...
March 2017: Yonago Acta Medica
https://www.readbyqxmd.com/read/28331424/gastric-schwannoma-with-enlargement-of-the-regional-lymph-nodes-resected-using-laparoscopic-distal-gastrectomy-report-of-a-patient
#13
Shota Shimizu, Hiroaki Saito, Yusuke Kono, Yuki Murakami, Hirohiko Kuroda, Tomoyuki Matsunaga, Yoji Fukumoto, Tomohiro Osaki, Yoshiyuki Fujiwara
Preoperative differential diagnosis of gastric submucosal tumors has generally been difficult because they are covered with normal mucosa. However, recent advances in endoscopic ultrasound (EUS)-guided sampling of submucosal gastrointestinal lesions have made it possible to achieve preoperative differential diagnosis of gastric submucosal tumors. A 76-year-old woman was referred to our hospital with a gastric submucosal tumor. The tumor was observed in the antrum of the stomach. It was preoperatively diagnosed as a schwannoma after immunohistochemical evaluation of a biopsy specimen, obtained using endoscopic ultrasound-guided fine needle aspiration...
March 2017: Yonago Acta Medica
https://www.readbyqxmd.com/read/28331423/a-case-of-unruptured-right-gastroepiploic-artery-aneurysm-successfully-resected-by-laparoscopic-surgery
#14
Yuki Murakami, Hiroaki Saito, Shota Shimizu, Yusuke Kono, Hirohiko Kuroda, Tomoyuki Matsunaga, Yoji Fukumoto, Tomohiro Osaki, Yoshiyuki Fujiwara
A 50-year-old woman was admitted to our hospital to undergo surgery to remove a pituitary adenoma. Preoperative dynamic computed tomography revealed an incidental right gastroepiploic arterial aneurysm (GEAA). After removal of the pituitary adenoma, we performed a laparoscopic right gastroepiploic aneurysmectomy. The postoperative course was uneventful. Right GEAAs should be treated at diagnosis owing to the high possibility of rupture. Laparoscopic right gastroepiploic aneurysmectomy is feasible and should be considered for the treatment of right GEAAs...
March 2017: Yonago Acta Medica
https://www.readbyqxmd.com/read/28331422/evaluation-of-incontinence-after-robot-assisted-laparoscopic-radical-prostatectomy-using-the-international-consultation-on-incontinence-modular-questionnaire-short-form-and-noting-the-number-of-safety-pads-needed-by-japanese-patients
#15
Katsuya Hikita, Masashi Honda, Bunya Kawamoto, Panagiota Tsounapi, Kuniyasu Muraoka, Takehiro Sejima, Atsushi Takenaka
BACKGROUND: The definition of continence after robot-assisted laparoscopic radical prostatectomy (RARP) has not been consistently defined, with many studies only noting the amount of safety pads used. We therefore examined what definition of continence would be appropriate, employing both the International Consultation on Incontinence Modular Questionnaire Short Form (ICIQ-SF) and the number of pads used by patients. We also evaluated the relationship between the number of pads used and degree of incontinence...
March 2017: Yonago Acta Medica
https://www.readbyqxmd.com/read/28331421/factors-affecting-intention-to-undergo-dementia-screening
#16
Shinya Takeda, Maki Ota, Toshiatsu Taniguchi
BACKGROUND: In the present study, we focused on the main perception-related factors that affect people's intention to undergo dementia screening. METHODS: The 344 subjects that answered all the survey questions were included in the analysis. Data on the following variables were collected: Basic attributes such as age, sex, years of education, and number of people in the household; degree of intention to undergo dementia screening; degree of awareness of the seriousness of the consequences of dementia; degree of awareness that the person may someday develop dementia; degree of awareness of their ability to prevent dementia; availability of social support; degree of knowledge of lifestyle habits that can prevent dementia; role in the community and purpose in life...
March 2017: Yonago Acta Medica
https://www.readbyqxmd.com/read/28331420/serum-procalcitonin-in-patients-with-acute-liver-failure
#17
Takaaki Sugihara, Masahiko Koda, Toshiaki Okamoto, Kenichi Miyoshi, Tomomitsu Matono, Kenji Oyama, Keiko Hosho, Jun-Ichi Okano, Hajime Isomoto
BACKGROUND: Procalcitonin (PCT) is a known diagnostic marker of bacterial infection. There are no previous reports of PCT concerning acute liver failure (ALF). We evaluated the clinical value of serum PCT levels in patients with ALF. METHODS: Forty-four patients with acute hepatitis (19 men and 25 women; median age, 40 years; range, 20-79 years) were retrospectively enrolled from January 2001 and June 2015. PCT levels were measured by saved serum samples obtained within 3 days after admission...
March 2017: Yonago Acta Medica
https://www.readbyqxmd.com/read/28331419/falsely-elevated-serum-vitamin-b12-levels-were-associated-with-the-severity-and-prognosis-of-chronic-viral-liver-disease
#18
Takaaki Sugihara, Masahiko Koda, Toshiaki Okamoto, Kenichi Miyoshi, Tomomitsu Matono, Kenji Oyama, Keiko Hosho, Jun-Ichi Okano, Hajime Isomoto, Yoshikazu Murawaki
BACKGROUND: Vitamin B12 is stored primarily in the liver, and highly elevated serum vitamin B12 levels occur in acute hepatitis and severe alcoholic liver disease. We evaluated the relationship between vitamin B12 levels and liver disease severity and long term prognosis in patients with chronic viral hepatitis and cirrhosis. METHODS: We enrolled 90 patients (57 men, 33 women) with chronic viral hepatitis and cirrhosis who admitted to our hospital as a prospective cohort study...
March 2017: Yonago Acta Medica
https://www.readbyqxmd.com/read/28331418/optimization-of-pcr-condition-the-first-study-of-high-resolution-melting-technique-for-screening-of-apoa1-variance
#19
Hesty Wahyuningsih, Ferdy K Cayami, Udin Bahrudin, Mochamad A Sobirin, Farmaditya Ep Mundhofir, Sultana Mh Faradz, Ichiro Hisatome
BACKGROUND: High resolution melting (HRM) is a post-PCR technique for variant screening and genotyping based on the different melting points of DNA fragments. The advantages of this technique are that it is fast, simple, and efficient and has a high output, particularly for screening of a large number of samples. APOA1 encodes apolipoprotein A1 (apoA1) which is a major component of high density lipoprotein cholesterol (HDL-C). This study aimed to obtain an optimal quantitative polymerase chain reaction (qPCR)-HRM condition for screening of APOA1 variance...
March 2017: Yonago Acta Medica
https://www.readbyqxmd.com/read/28331417/%C3%AE-tocotrienol-inhibits-tgf-%C3%AE-1-induced-contractile-phenotype-expression-of-human-airway-smooth-muscle-cells
#20
Takehito Fukushima, Akira Yamasaki, Tomoya Harada, Hiroki Chikumi, Masanari Watanabe, Ryota Okazaki, Miki Takata, Yasuyuki Hasegawa, Jun Kurai, Masaaki Yanai, Akihiro Yamamoto, Yuriko Sueda, Andrew J Halayko, Eiji Shimizu
BACKGROUND: Tocotrienols, members of the vitamin E family, exist in four different isoforms (α, β, γ and δ tocotrienol) that have can be protective against brain damage, as well as having anticancer effects in vivo and in vitro. We have shown that γ-tocotrienol inhibits human airway smooth muscle cell proliferation and migration induced by platelet-derived growth factor (PDGF)-BB by suppressing RhoA activation. In this study, we tested whether γ-tocotrienol modulates transforming growth factor (TGF) -β-induced induction of human airway smooth muscle (ASM) into a contractile phenotype and concomitant synthesis of extracellular matrix proteins...
March 2017: Yonago Acta Medica
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