journal
https://read.qxmd.com/read/38155614/a-survey-of-informed-consent-in-patients-with-dementia-in-the-us-and-japan
#21
JOURNAL ARTICLE
Yoshihiko Iijima
This study aimed to confirm the reality of family-focused medical treatment of dementia in Japan and the US. It conducted a questionnaire survey on informed consent from patients with dementia among neurologists and psychiatrists in four prefectures in the Tokai Region (Aichi, Gifu, Mie, and Shizuoka) and dementia specialists in the US. Of the responses, 120 (39.7% response rate) and 20 (5.9% response rate) were obtained, respectively. In obtaining informed consent from patients with dementia, 75 Japanese specialists (62...
November 2023: Nagoya Journal of Medical Science
https://read.qxmd.com/read/38155613/dupilumab-suppresses-relapsing-chronic-eosinophilic-pneumonia-with-severe-asthma
#22
Nami Masumoto, Chiyako Oshikata, Ryo Nakadegawa, Yuto Motobayashi, Reeko Osada, Saki Manabe, Takeshi Kaneko, Naomi Tsurikisawa
Dupilumab-induced hypereosinophilia is mediated by blockade of the IL-4/IL-13 pathway, which reduces eosinophil migration from peripheral blood. The increase in peripheral blood eosinophils may lead to chronic eosinophilic pneumonia (CEP) and/or eosinophilic granulomatosis with polyangiitis, but a direct causal connection between dupilumab and eosinophilic lung diseases has not been established. A 33-year-old Japanese woman with bronchial asthma since age three was treated with fluticasone propionate plus salmeterol twice daily after several asthma exacerbations at age 17...
November 2023: Nagoya Journal of Medical Science
https://read.qxmd.com/read/38155612/the-clinical-and-histopathological-characteristics-of-thyroid-gland-diseases-in-adolescents-requiring-surgical-treatment-a-ten-year-follow-up-study
#23
JOURNAL ARTICLE
Vladimir Pantelic, Sasa Zunjic, Ivan Paunovic, Vladan Zivaljevic, Miljana Pilipovic, Ivan Radosavljevic
The present research aimed to determine the clinical and pathohistological characteristics of thyroid gland diseases in adolescents who were previously surgically treated at the Endocrine Surgery Center of the University Medical Center of Serbia from 01/01/2001 to 01/01/2011. The study covered 170 patients of both sexes from the population of adolescents (aged 16 to 20 years) with various malignant and benign thyroid gland diseases. The data for this study were extracted from the medical histories of patients and the electronic database of the Center for Endocrine Surgery...
November 2023: Nagoya Journal of Medical Science
https://read.qxmd.com/read/37829493/development-and-validation-of-a-professional-autonomy-scale-for-japanese-midwives
#24
JOURNAL ARTICLE
Satsuki Obata, Shigemi Iriyama
Japanese midwives are required to autonomously perform midwifery diagnosis and maternity care. However, education to promote the professional autonomy of midwives is inadequate, and previous studies have not been able to identify a measure for it. This study aimed to develop a professional autonomy scale for midwives, to be used for the education and career advancement of Japanese midwives. The Midwives Professional Autonomy Scale extracted items from the midwives' "autonomy" and "specialty" literature, and 10 professionals verified the surface and content validity of the scale...
August 2023: Nagoya Journal of Medical Science
https://read.qxmd.com/read/37829492/the-usefulness-of-the-apparent-diffusion-coefficient-value-in-diagnosing-acute-spinal-cord-ischemia
#25
JOURNAL ARTICLE
Norikazu Koori, Joe Senda, Takehiro Naito
The purpose of our study was to assess the usefulness of the apparent diffusion coefficient (ADC) value in differentiating between a normal spinal cord and a spinal cord with acute ischemia. Control group of 113 and 8 acute spinal cord ischemia patients were enrolled in this study. The ADC values were measured when diffusion-weighted imaging was first performed after the onset of acute spinal cord ischemia. The mean ADC value each of the control group and acute spinal cord ischemia patients was 0.99 ± 0...
August 2023: Nagoya Journal of Medical Science
https://read.qxmd.com/read/37829491/cardiac-rehabilitation-in-a-heart-failure-patient-using-customized-cardiac-support-net-treatment-a-case-report
#26
Kiyonori Kobayashi, Toshiaki Akita, Sho Akita, Hideki Ito, Sachie Terazawa, Masato Mutsuga, Akihiko Usui
At our hospital, we are conducting the "Clinical Study of a Patient-Specific Cardiac Support Net for Dilated Cardiomyopathy (jRCTs042180025)", a multi-facility clinical study of a customized cardiac support net (CSN). Here, we describe the cardiac rehabilitation (CR) of a heart failure (HF) patient after CSN treatment. The patient was a 65-year-old man who exhibited dilated cardiomyopathy (DCM) because of left ventricular non-compaction; his New York Heart Association status was class III. In November 2019, he received CSN treatment...
August 2023: Nagoya Journal of Medical Science
https://read.qxmd.com/read/37829490/propofol-elicits-apoptosis-and-attenuates-cell-growth-in-esophageal-cancer-cell-lines
#27
JOURNAL ARTICLE
Rui Zhou, Yuko Konishi, Ailing Zhang, Kimitoshi Nishiwaki
Propofol is a pharmaceutical agent commonly used as an intravenous anesthetic in surgical treatments and a sedative in intensive care. However, it is largely unknown how exposure to propofol affects the proliferation, invasion, and apoptosis of neoplastic cells in esophageal cancer. In this study, we sought to elucidate the impact of propofol exposure on the growth properties of human esophageal cancer cell lines in vitro. We treated two human esophageal cancer cell lines, KYSE30 and KYSE960, with up to 10 µg/mL of propofol for 12-36 h...
August 2023: Nagoya Journal of Medical Science
https://read.qxmd.com/read/37829489/association-between-national-institutes-of-health-stroke-scale-and-functional-independence-measure-scores-in-patients-with-ischemic-stroke-from-convalescent-rehabilitation-outcomes
#28
JOURNAL ARTICLE
Joe Senda, Keiichi Ito, Tomomitsu Kotake, Masanori Mizuno, Hideo Kishimoto, Keizo Yasui, Hiroko Nakagawa-Senda, Masahisa Katsuno, Yoshihiro Nishida, Gen Sobue
We investigated the associations among neurological severity, activities of daily living (ADLs), and clinical factors in patients with ischemic stroke in convalescent rehabilitation outcome. The study sample included 723 patients with ischemic stroke (484 men and 239 women; mean age, 73.2 ± 8.5 years) for inpatient convalescent rehabilitation. National Institutes of Health Stroke Scale (NIHSS) was used to measure the neurological severity, and Functional Independence Measure (FIM) was used to assess ADLs at discharge...
August 2023: Nagoya Journal of Medical Science
https://read.qxmd.com/read/37829488/a-rare-case-of-the-axillary-necrotizing-fasciitis
#29
Hiroki Ito, Shinsuke Takeda, Yuji Matsuno, Hiroshi Takahashi, Ken-Ichi Yamauchi
Necrotizing fasciitis is a rapidly progressive, life-threatening soft tissue infection that needs acute surgical intervention and other types of supportive care. The upper extremities are a less frequent site for this infection than the lower extremities. Axillary necrotizing fasciitis is quite rare and bears a high risk of iatrogenic neurovascular injuries. We report a severe case of a 39-year-old man with a right axillary necrotizing fasciitis caused by Streptococcus pyogenes . While dealing with important nerves and blood vessels at the initial emergency surgery, we marked and preserved them with vascular tapes...
August 2023: Nagoya Journal of Medical Science
https://read.qxmd.com/read/37829487/the-study-of-exercise-therapy-using-a-virtual-reality-system-on-healthy-subjects-assuming-hospital-use-and-intradialytic-exercise
#30
JOURNAL ARTICLE
Ren Takahashi, Hiroki Yabe, Takashi Hibino, Sayumi Morishita, Mina Watanabe, Katsumasa Nishioka, Hideaki Ishikawa
This study aimed to investigate the basic data on the effectiveness and safety of the system in healthy subjects using an immersive virtual reality (VR) exercise system specialized for therapeutic exercise therapy during dialysis or hospital use. A total of 15 healthy adult subjects performed four exercises, namely lifting and rowing exercises using VR and each movement exercise without VR (control). The simulator sickness questionnaire (SSQ) was administered pre- and post-operatively to assess for VR sickness...
August 2023: Nagoya Journal of Medical Science
https://read.qxmd.com/read/37829486/local-hyperthermia-with-built-in-endoscopy-for-radioresistant-cervical-cancer-a-case-series
#31
Nobuhisa Yoshikawa, Yoshiyuki Itoh, Tetsuya Matsukawa, Mariko Kawamura, Keiichiro Yamada, Seiji Nakamura, Hiroaki Kajiyama
We evaluated the efficacy and safety of an endoscope-embedded transvaginal laser hyperthermia system for superficial cervical cancer that remained in the cervix after radiotherapy. We developed an innovative endoscope-embedded hyperthermia system consisting of a diode laser device, a temperature control unit, an endoscope control unit, and a transvaginal probe. Superficial lesions of recurrent or residual cervical cancer on the uterine cervix or vaginal wall after radiotherapy were eligible for this study. A total of four cases of three patients were eligible for this treatment...
August 2023: Nagoya Journal of Medical Science
https://read.qxmd.com/read/37829485/the-association-between-early-rehabilitation-and-ambulatory-ability-at-discharge-in-patients-with-hip-fractures-at-acute-phase-rehabilitation-wards-a-survey-of-the-japan-association-of-rehabilitation-database
#32
JOURNAL ARTICLE
Koji Hattori, Hiroko Kamitani, Yusuke Suzuki, Nariaki Shiraishi, Takahiro Hayashi, Daisuke Matsumoto, Motoya Sugiyama, Hitoshi Komiya, Masafumi Kuzuya
This study aimed to examine the effectiveness of early rehabilitation in patients with femoral neck fractures admitted to acute care settings in Japan using the data registered with the Japan Association of Rehabilitation Databases (JARD). We included data for 401 patients (out of 3088 patients) aged ≥ 65 years (85 males, 316 females) from nine hospitals who sustained a femoral neck fracture between July 2005 and September 2015. Using the number of days until surgery or the number of days until the start of rehabilitation or both as the explanatory variables, and the indoor mobility at discharge as the outcome variable, we calculated the adjusted rate ratio (ARR) and 95% confidence interval (CI) using Poisson regression analysis (age, sex, cognitive impairment, concurrent symptoms, and previous history of fracture adjusted as covariates)...
August 2023: Nagoya Journal of Medical Science
https://read.qxmd.com/read/37829484/trends-of-travel-burdens-to-access-cancer-care-among-children-with-cancer-analysis-of-a-population-based-cancer-registry-data-in-aichi-japan
#33
JOURNAL ARTICLE
Anna Tsutsui, Natsumiko Ando, Yukari Taniyama, Takako Fujimaki, Masanori Kawaura, Keitaro Matsuo, Hidemi Ito, Yuko Ohno
Centralization of childhood cancer treatment in specialized hospitals is necessary for quality treatment and care, but imposes a time and cost burden for patients and their families. We investigated the 20-year trend in the patients' car travel burden to reach cancer-care hospitals in Aichi Prefecture, Japan. From the Aichi population-based cancer registry data, 1,741 cases diagnosed in 1998-2017 under 15 years of age were extracted and assigned to three treatment groups: invasive treatment (n = 697), radiotherapy (n = 371), or chemotherapy groups (n = 1,462), allowing for duplicate assignment...
August 2023: Nagoya Journal of Medical Science
https://read.qxmd.com/read/37829483/urethral-identification-using-three-dimensional-magnetic-resonance-imaging-and-interfraction-urethral-motion-evaluation-for-prostate-stereotactic-body-radiotherapy
#34
JOURNAL ARTICLE
Yutaka Kato, Shintaro Okumiya, Kuniyasu Okudaira, Junji Ito, Motoki Kumagai, Takeshi Kamomae, Yumiko Noguchi, Mariko Kawamura, Shunichi Ishihara, Shinji Naganawa
Prostatic urethra identification is crucial in prostate stereotactic body radiotherapy (SBRT) to reduce the risk of urinary toxicity. Although computed tomography (CT) with a catheter is commonly employed, it is invasive, and catheter placement may displace the urethral position, resulting in possible planning inaccuracies. However, magnetic resonance imaging (MRI) can overcome these weaknesses. Accurate urethral identification and minimal daily variation could ensure a highly accurate SBRT. In this study, we investigated the usefulness of a three-dimensional (3D) T2-weighted (T2W) sequence for urethral identification, and the interfractional motion of the prostatic urethra on CT with a catheter and MRI without a catheter for implementing noninvasive SBRT...
August 2023: Nagoya Journal of Medical Science
https://read.qxmd.com/read/37829482/%C3%AF-editors-choice%C3%AF-supernatant-from-activated-omentum-accelerates-wound-healing-in-diabetic-mice-wound-model
#35
JOURNAL ARTICLE
Yu Li, Kazunobu Hashikawa, Katsumi Ebisawa, Miki Kambe, Shinichi Higuchi, Yuzuru Kamei
Diabetic wounds are considered one of the most frequent and severe complications of diabetes mellitus. Recently, the omentum has been used in diabetic wound healing because of its tissue repair properties. The activated omentum is richer in growth factors than the inactivated, thereby contributing to the wound healing process. To further investigate the effect of activated omentum conditioned medium (aOCM) on diabetic wound healing, we injected supernatant from aOCM, saline-OCM (sOCM), inactivated-OCM (iOCM), and medium (M) subcutaneously upon creation of a cutaneous wound healing model in diabetic mice...
August 2023: Nagoya Journal of Medical Science
https://read.qxmd.com/read/37829481/real-world-effectiveness-of-ustekinumab-for-patients-with-ulcerative-colitis-a-systematic-review-and-meta-analysis
#36
REVIEW
Genta Uchida, Masanao Nakamura, Takeshi Yamamura, Tomoyuki Tsuzuki, Hiroki Kawashima
Ustekinumab has recently been approved for the treatment of ulcerative colitis (UC) based on data from clinical trials. However, the effectiveness of ustekinumab in patients with UC in a real-world setting remains unclear. Hence, in this meta-analysis, we aimed to evaluate the effectiveness of ustekinumab in a real-world setting and to investigate the predictors of its effectiveness. A comprehensive literature search was performed to examine the effectiveness of ustekinumab in UC patients admitted between January 2019 and December 2021...
August 2023: Nagoya Journal of Medical Science
https://read.qxmd.com/read/37829480/a-nerve-to-implant-distance-as-a-novel-predictor-for-lateral-femoral-cutaneous-nerve-injuries-after-anterior-subcutaneous-pelvic-internal-fixation
#37
JOURNAL ARTICLE
Shinsuke Takeda, Michiro Yamamoto, Yoshihiro Tanaka, So Mitsuya, Ken-Ichi Yamauchi, Hitoshi Hirata
Although anterior subcutaneous pelvic internal fixation is a valuable tool for the reduction and fixation of unstable pelvic ring injuries, lateral femoral cutaneous nerve irritation by the implant is the most common complication. This study aimed to investigate the association between the nerve-to-implant distance and the postoperative lateral femoral cutaneous nerve symptom. Patients who underwent anterior subcutaneous pelvic internal fixation between 2016 and 2019 were retrospectively analyzed. Lateral femoral cutaneous nerve status was defined as follows: not identified, nerve-to-implant distance <13 mm, and ≥13 mm...
August 2023: Nagoya Journal of Medical Science
https://read.qxmd.com/read/37829479/role-of-serum-n-6-polyunsaturated-fatty-acids-in-the-development-of-acute-coronary-syndromes
#38
JOURNAL ARTICLE
Naoya Inoue, Shuji Morikawa, Toyoaki Murohara
n-3 polyunsaturated fatty acids (PUFAs) have an inhibitory effect on the development of coronary artery disease (CAD). However, whether n-6 PUFAs, dihomo-gamma-linolenic acid (DGLA), and arachidonic acid (AA) play a role in the development of CAD remains unclear. This study investigated the association between PUFAs and the risk of developing acute coronary syndrome (ACS) using the lipid and PUFAs data of patients who received percutaneous coronary intervention (PCI) for either non-emergent conditions (staged group) or ACS (ACS group)...
August 2023: Nagoya Journal of Medical Science
https://read.qxmd.com/read/37829478/job-satisfaction-among-myanmar-working-population-a-cross-sectional-study
#39
JOURNAL ARTICLE
Pa Pa Soe, Su Yi Toe, Zar Lwin Hnin, Ma Ma Thant, Nyi Nyi Latt, Nang Hla Hla Htay, Than Than Aung, Myint Sann, Nang Hla Hla Win
The gap between expectations and reality could lead to low job satisfaction. Although much literature has been described on job satisfaction among different categories of people, more research is needed to acknowledge the judgment of job satisfaction among some of the Myanmar working population. The study aims to find out the satisfaction level of a job and the factors related to it. The cross-sectional study was conducted in January 2019 by calling for face-to-face interviews with 536 respondents selected using a convenient sampling technique using a pre-tested questionnaire...
August 2023: Nagoya Journal of Medical Science
https://read.qxmd.com/read/37829477/preoperative-frailty-as-a-predictive-factor-for-postoperative-complications-in-patients-with-pancreatic-cancer
#40
JOURNAL ARTICLE
Makoto Onji, Shinji Kakizoe, Koichi Naito, Kenjiro Date, Asuka Nakai, Kanami Shimizu, Masatake Suyama, So Nakamura, Hirotaka Kuga, Kazuyoshi Nishihara
Frailty is considered one of the most important indicators of a patient's general condition. However, only a few studies have investigated the association between preoperative frailty and postoperative complications in pancreatic cancer. Therefore, this study aimed to examine this association in patients with pancreatic cancer. We retrospectively reviewed 52 consecutive patients who underwent pancreatectomy for pancreatic cancer between July 2019 and March 2021. Patients were classified into two groups according to the presence of postoperative complications...
August 2023: Nagoya Journal of Medical Science
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