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Ultrasound in Medicine & Biology

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https://www.readbyqxmd.com/read/28533004/validation-of-navigation-ultrasound-for-clavicular-length-measurement
#1
Anders Thorsmark Høj, Chiara Villa, Ole M Christensen, Søren Torp-Pedersen, Søren Overgaard, Lars H Frich
Accurate clavicular length measurement is considered important for the selection of patients requiring surgical treatment after a midclavicular fracture. As radiographic length measurements can be inaccurate to varying degrees, new measurement methods are needed. Use of novel technology, navigation ultrasound, to deliver accurate measurements seems promising. To examine the reliability and validity of navigation ultrasound for length measurements of the clavicle, a study was performed using length measurements performed before forensic autopsies from 2012 to 2013...
May 19, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28533003/rectus-femoris-echo-intensity-correlates-with-muscle-strength-but-not-endurance-in-younger-and-older-men
#2
Jacob A Mota, Matt S Stock
We examined correlations between echo intensity and muscle strength and endurance. Rectus femoris echo intensity, maximal voluntary contraction (MVC) force and time to task failure during a 50% MVC task were determined for 12 younger (mean age = 25 y) and 13 older (mean age = 74 y) men. Bivariate correlations between echo intensity and normalized MVC force were similar for younger and older men, but was only statistically significant for the latter (younger r = -0.559, p = 0.059; older r = -0.580, p = 0...
May 19, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28528019/us-elastography-using-carotid-artery-pulsation-may-increase-the-diagnostic-accuracy-for-thyroid-nodules-with-us-pathology-discordance
#3
Yoon Joo Cho, Eun Ju Ha, Miran Han, Jin Wook Choi
This study evaluated the diagnostic performance of ultrasound elastography (USE) using carotid arterial pulsation and determined the reproducibility of USE for thyroid nodules. A total of 148 patients with 173 thyroid nodules participated. The mean elasticity contrast index (ECI) was significantly higher in malignant nodules (3.1 ± 1.5) than in benign nodules (1.7 ± 0.8) (p < 0.001). When a cut-off ECI value of 3.5 was used, the diagnostic accuracy (78.6%) of gray-scale ultrasound (US) + ECI was the highest compared with that of the gray-scale US (76...
May 17, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28522150/implementation-of-a-wearable-ultrasound-device-for-the-overnight-monitoring-of-tongue-base-deformation-during-obstructive-sleep-apnea-events
#4
Chi-Kai Weng, Jeng-Wen Chen, Po-Yang Lee, Chih-Chung Huang
Obstructive sleep apnea (OSA) is a breathing disorder characterized by the repeated collapse of the pharyngeal airway during sleep. Previous studies have reported that tongue base deformation may be a major contributing factor. However, overnight monitoring of tongue motion in patients with OSA has previously been impracticable. We developed a wearable ultrasound device for prolonged recording during natural sleep of the changes in tongue base thickness (TBT) in patients with OSA. The maximum TBT was fed into a polysomnography system so that physiologic signals and TBT data were simultaneously monitored...
May 15, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28522149/measuring-absolute-blood-perfusion-in-mice-using-dynamic-contrast-enhanced-ultrasound
#5
Abbas Shirinifard, Suresh Thiagarajan, Melissa D Johnson, Christopher Calabrese, András Sablauer
We investigated the feasibility of estimating absolute tissue blood perfusion using dynamic contrast-enhanced ultrasound (CEUS) imaging in mice. We developed a novel method of microbubble administration and a model-free approach to estimate absolute kidney perfusion, and explored the kidney as a reference organ to estimate absolute perfusion of a neuroblastoma tumor. We performed CEUS on the kidneys of CD1 nude mice using the VisualSonics VEVO 2100 imaging system. We estimated individual kidney blood perfusion using the burst-replenishment (BR) technique...
May 15, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28511961/pre-operative-evaluation-of-axillary-lymph-node-status-in-patients-with-suspected-breast-cancer-using-shear-wave-elastography
#6
Ji Hyun Youk, Eun Ju Son, Jeong-Ah Kim, Hye Mi Gweon
The aim of this study was to evaluate shear wave elastography (SWE) for pre-operative evaluation of axillary lymph node (LN) status in patients with suspected breast cancer. A total of 130 axillary LNs in 130 patients who underwent SWE before fine-needle aspiration, core biopsy or surgery were analyzed. On gray-scale images, long and short axes, shape (elliptical or round), border (sharp or unsharp) and cortical thickening (concentric, eccentric or no fatty hilum) of LNs were assessed. On SWE, mean, maximum, minimum, standard deviation and the lesion-to-fat ratio (Eratio) values of elasticity were collected...
May 13, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28502665/can-the-contrast-enhanced-ultrasound-washout-rate-be-used-to-predict-microvascular-invasion-in-hepatocellular-carcinoma
#7
Wei Zhu, Xiachuan Qing, Feng Yan, Yan Luo, Yongzhong Li, Xiang Zhou
The objective of this study was to investigate use of the washout rate of hepatocellular carcinoma on contrast-enhanced ultrasound (CEUS) for pre-operative determination of the presence of microvascular invasion. The study included 271 patients who underwent liver resection for hepatocellular carcinoma between April 2008 and December 2012, and were examined with contrast-enhanced ultrasound before surgery. Patients were followed up at 3-mo intervals for 3 y. Four washout patterns were classified according to the start time of washout: rapid, portal, delayed and slow...
May 11, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28501327/echo-particle-image-velocimetry-for-estimation-of-carotid-artery-wall-shear-stress-repeatability-reproducibility-and-comparison-with-phase-contrast-magnetic-resonance-imaging
#8
Arati Gurung, Phillip E Gates, Luciano Mazzaro, Jonathan Fulford, Fuxing Zhang, Alex J Barker, Jean Hertzberg, Kunihiko Aizawa, William D Strain, Salim Elyas, Angela C Shore, Robin Shandas
Measurement of hemodynamic wall shear stress (WSS) is important in investigating the role of WSS in the initiation and progression of atherosclerosis. Echo particle image velocimetry (echo PIV) is a novel ultrasound-based technique for measuring WSS in vivo that has previously been validated in vitro using the standard optical PIV technique. We evaluated the repeatability and reproducibility of echo PIV for measuring WSS in the human common carotid artery. We measured WSS in 28 healthy participants (18 males and 10 females, mean age: 56 ± 12 y)...
May 10, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28499496/relationships-between-quantitative-pulse-echo-ultrasound-parameters-from-the-superficial-zone-of-the-human-articular-cartilage-and-changes-in-surface-roughness-collagen-content-or-collagen-orientation-caused-by-early-degeneration
#9
Wataru Kiyan, Akira Ito, Yasuaki Nakagawa, Shogo Mukai, Koji Mori, Tatsuo Arai, Eiichiro Uchino, Yasushi Okuno, Hiroshi Kuroki
We aimed to quantitatively investigate the relationship between amplitude-based pulse-echo ultrasound parameters and early degeneration of the knee articular cartilage. Twenty samples from six human femoral condyles judged as grade 0 or 1 according to International Cartilage Repair Society grading were assessed using a 15-MHz pulsed-ultrasound 3-D scanning system ex vivo. Surface roughness (Rq), average collagen content (A1) and collagen orientation (A12) in the superficial zone of the cartilage were measured via laser microscopy and Fourier transform infrared imaging spectroscopy...
May 9, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28495300/aortic-valve-stenosis-increases-helical-flow-and-flow-complexity-a-study-of-intra-operative-cardiac-vector-flow-imaging
#10
Kristoffer Lindskov Hansen, Hasse Møller-Sørensen, Jesper Kjaergaard, Maiken Brit Jensen, Jørgen Arendt Jensen, Michael Bachmann Nielsen
Aortic valve stenosis alters blood flow in the ascending aorta. Using intra-operative vector flow imaging on the ascending aorta, secondary helical flow during peak systole and diastole, as well as flow complexity of primary flow during systole, were investigated in patients with normal, stenotic and replaced aortic valves. Peak systolic helical flow, diastolic helical flow and flow complexity during systole differed between the groups (p < 0.0001), and correlated to peak systolic velocity (R = 0.94, 0...
May 8, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28483580/investigation-of-non-linear-chirp-coding-for-improved-second-harmonic-pulse-compression
#11
Muhammad Arif, Muhammad Asim Ali, Muhammad Mujtaba Shaikh, Steven Freear
Non-linear frequency-modulated (NLFM) chirp coding was investigated to improve the pulse compression of the second harmonic chirp signal by reducing the range side lobe level. The problem of spectral overlap between the fundamental component and second harmonic component (SHC) was also investigated. Therefore, two methods were proposed: method I for the non-overlap condition and method II with the pulse inversion technique for the overlap harmonic condition. In both methods, the performance of the NLFM chirp was compared with that of the reference LFM chirp signals...
May 5, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28483579/comparison-of-2-d-shear-wave-elastography-and-transient-elastography-for-assessing-liver-fibrosis-in-chronic-hepatitis-b
#12
Jie Zeng, Jian Zheng, Zeping Huang, Shigao Chen, Jing Liu, Tao Wu, Rongqin Zheng, Mingde Lu
This study compared 2-D shear wave elastography (SWE) and transient elastography (TE) for liver fibrosis staging in patients with chronic hepatitis B (CHB) infection using liver biopsy as the reference standard. Patients with CHB infection who underwent liver biopsy were consecutively included. After exclusions, 257 patients were analyzed. Two-dimensional SWE resulted in a significantly higher rate of reliable measurements (98.1%, 252/257) than TE (93.0%, 239/257) (p = 0.011). Liver stiffness measurements of the two examinations exhibited a strong correlation (r = 0...
May 5, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28479088/ultrasound-and-intra-clot-microbubbles-enhanced-catheter-directed-thrombolysis-in%C3%A2-vitro-and-in%C3%A2-vivo
#13
Shunji Gao, Qiong Zhu, MengJiao Guo, Yuan Gao, Xiaoxiao Dong, Zhong Chen, Zheng Liu, Feng Xie
Insufficient penetration of microbubbles (MBs) into the vessel-obstructing thrombi significantly reduces the effectiveness of ultrasound thrombolysis (UT). The widely performed catheter-directed therapy (CDT) makes it possible to increase the local concentration of MBs in the clot. In an occluded vessel with a bypass, treatment of fresh human whole blood clots with CDT-based UT (intra-clot injection of MBs and urokinase, with ultrasound exposure) resulted in a significantly higher percentage of weight loss (35...
May 4, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28476311/transcranial-functional-ultrasound-imaging-in-freely-moving-awake-mice-and-anesthetized-young-rats-without-contrast-agent
#14
Elodie Tiran, Jérémy Ferrier, Thomas Deffieux, Jean-Luc Gennisson, Sophie Pezet, Zsolt Lenkei, Mickaël Tanter
Functional ultrasound (fUS) imaging by ultrasensitive Doppler detection of blood volume was previously reported to measure adult rat brain activation and functional connectivity with unmatched spatiotemporal sampling (100 μm, 1 ms), but skull-induced attenuation of ultrasonic waves imposed skull surgery or contrast agent use. Also, fUS feasibility remains to be validated in mice, a major pre-clinical model organism. In the study described here, we performed full-depth ultrasensitive Doppler imaging and 3-D Doppler tomography of the entire mouse brain under anesthesia, non-invasively through the intact skull and skin, without contrast agents...
May 2, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28461064/evaluation-of-transabdominal-ultrasound-with-oral-cellulose-based-contrast-agent-in-the-detection-and-surveillance-of-gastric-ulcer
#15
Zhijun Liu, Jintao Guo, Shupeng Wang, Ying Zhao, Zhining Liu, Jing Li, Weidong Ren, Shaoshan Tang, Limei Xie, Ying Huang, Siyu Sun, Liping Huang
The aim of this study was to assess the role of transabdominal ultrasound with cellulose-based oral contrast agent (TUS-OCCA) in the detection and surveillance of gastric ulcer. The study was approved by the institutional review board at Shengjing Hospital of China Medical University. A total of 124 consecutive patients with benign gastric ulcer diagnosed by gastroscopy and biopsy were enrolled. Serial TUS-OCCA (approximately 1 exam every 2 wk) was performed to monitor the effects of treatment, and additional interventions were planned according to the results...
April 28, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28461063/low-intensity-pulsed-ultrasound-promotes-exercise-induced-muscle-hypertrophy
#16
Liang Tang, Jing Zhang, Xinjuan Zhao, Nan Li, Wenqi Jian, Shuxin Sun, Jianzhong Guo, Lijun Sun, Dean Ta
The purpose of this study was to investigate whether low-intensity pulsed ultrasound (LIPUS) promotes exercise-induced muscle hypertrophy. Twenty-four adult Sprague-Dawley (SD) rats were randomly assigned to three groups (n = 8 per group): normal control group (NC), treadmill exercise group (TE) and treadmill exercise + LIPUS group (TE + LIPUS). The TE + LIPUS group received a LIPUS treatment (1 MHz, 30 mW/cm(2)) at the gastrocnemius for 20 min/d after treadmill exercise. The TE group was sham-treated...
April 28, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28457632/low-intensity-pulsed-ultrasound-induced-spinal-fusion-is-coupled-with-enhanced-calcitonin-gene-related-peptide-expression-in-rat-model
#17
Xiao-Yi Zhou, Xi-Ming Xu, Sui-Yi Wu, Fei Wang, Zi-Cheng Zhang, Yi-Lin Yang, Ming Li, Xian-Zhao Wei
Low-intensity pulsed ultrasound (LIPUS) has been found to accelerate fracture healing. In this study, we analyzed the role of calcitonin gene-related peptide (CGRP) in a rat spinal fusion model treated with LIPUS. The results revealed that LIPUS significantly increases bone formation, and the process was coupled with elevated CGRP innervation. CGRP was located in fibrous tissue, closely surrounding the allograft and newly formed cartilage. The density of CGRP peaked at week 3 after surgery in both the control (non-LIPUS-treated) and LIPUS-treated groups...
April 27, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28457631/quantitative-assessment-of-skin-stiffness-in-localized-scleroderma-using-ultrasound-shear-wave-elastography
#18
Liyun Wang, Feng Yan, Yujia Yang, Xi Xiang, Li Qiu
The purpose of this study was to evaluate the usefulness of ultrasound shear-wave elastography (US-SWE) in characterization of localized scleroderma (LS), as well as in the disease staging. A total of 21 patients with 37 LS lesions were enrolled in this study. The pathologic stage (edema, sclerosis or atrophy) of the lesions was characterized by pathologic examination. The skin elastic modulus (E-values including Emean, Emin, Emax and Esd) and thickness (h) was evaluated both in LS lesions and site-matched unaffected skin (normal controls) using US-SWE...
April 27, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28454842/inactivation-of-planktonic-escherichia-coli-by-focused-2-mhz-ultrasound
#19
Andrew A Brayman, Brian E MacConaghy, Yak-Nam Wang, Keith T Chan, Wayne L Monsky, Anna J McClenny, Thomas J Matula
This study was motivated by the desire to develop a non-invasive means to treat abscesses, and represents the first steps toward that goal. Non-thermal, high-intensity focused ultrasound (HIFU) was used to inactivate Escherichia coli (∼1 × 10(9) cells/mL) in suspension. Cells were treated in 96-well culture plate wells using 1.95-MHz ultrasound and incident focal acoustic pressures as high as 16 MPa peak positive and 9.9 MPa peak negative (free field measurements). The surviving fraction was assessed by coliform culture and the alamarBlue assay...
April 25, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28450036/dynamic-enhancement-of-b-mode-cardiac-ultrasound-image-sequences
#20
Antonios Perperidis, David Cusack, Audrey White, Norman McDicken, Tom MacGillivray, Tom Anderson
Limited contrast, along with speckle and acoustic noise, can reduce the diagnostic value of echocardiographic images. This study introduces dynamic histogram-based intensity mapping (DHBIM), a novel approach employing temporal variations in the cumulative histograms of cardiac ultrasound images to contrast enhance the imaged structures. DHBIM is then combined with spatial compounding to compensate for noise and speckle. The proposed techniques are quantitatively assessed (32 clinical data sets) employing (i) standard image quality measures and (ii) the repeatability of routine clinical measurements, such as chamber diameter and wall thickness...
April 24, 2017: Ultrasound in Medicine & Biology
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