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Ultrasound in Medicine & Biology

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https://www.readbyqxmd.com/read/28433441/role-of-contrast-enhanced-ultrasound-in-diagnosis-of-thyroid-nodules-in-acoustic-radiation-force-impulse-gray-zone
#1
Jia Zhan, Xue-Hong Diao, Lin Chen, Jia-Mei Jin, Yue Chen
The aim of this study was to evaluate the clinical value of contrast-enhanced ultrasound (CEUS) in the diagnosis of thyroid nodules in the acoustic radiation force impulse (ARFI) "gray zone" (the shear wave velocity is in the range 2.5-3 m/s). ARFI was performed before thyroidectomy in 70 patients with 200 thyroid nodules, and then CEUS was performed in 40 thyroid nodules in the "gray zone." The accuracy of ARFI for the 200 thyroid nodules was 82% (164/200). The accuracy of ARFI for the 40 "gray zone" thyroid nodules was 70% (28/40), whereas the accuracy of CEUS for the "gray zone" thyroid nodules was 90% (36/40)...
April 19, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28433440/spatial-compounding-technique-to-obtain-rotation-elastogram-a-feasibility-study
#2
AliArshad Kothawala, Sowmiya Chandramoorthi, N Ravi Kiran Reddy, Arun Kumar Thittai
The perception of stiffness and slipperiness of a breast mass on palpation is used by physicians to assess the level of suspicion of a lesion as being malignant or benign. However, most current ultrasound elastography imaging methods provide only stiffness-related information. There is no existing approach that provides information about the local rigid body rotation undergone by only a loosely bonded, asymmetrically oriented lesion subjected to a small quasi-static compression. The inherent poor lateral resolution in ultrasound imaging poses a limitation in estimating the local rigid body rotation...
April 19, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28433439/cardiac-amyloidosis-shows-decreased-diastolic-function-as-assessed-by-echocardiographic-parameterized-diastolic-filling
#3
Katrin Salman, Peter A Cain, Benjamin T Fitzgerald, Martin G Sundqvist, Martin Ugander
Cardiac amyloidosis is a rare but serious condition with poor survival. One of the early findings by echocardiography is impaired diastolic function, even before the development of cardiac symptoms. Early diagnosis is important, permitting initiation of treatment aimed at improving survival. The parameterized diastolic filling (PDF) formalism entails describing the left ventricular filling pattern during early diastole using the mathematical equation for the motion of a damped harmonic oscillator. We hypothesized that echocardiographic PDF analysis could detect differences in diastolic function between patients with amyloidosis and controls...
April 19, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28433438/analgesic-effects-of-transcutaneous-ultrasound-nerve-stimulation-in-a-rat-model-of-oxaliplatin-induced-mechanical-hyperalgesia-and-cold-allodynia
#4
Yueh-Ling Hsieh, Han-Yu Chen, Ching-Hsiang Yang, Chen-Chia Yang
This study investigated the effects and underlying mechanisms of therapeutic ultrasound (TUS) in a rat model of oxaliplatin-induced peripheral neuropathy. Animals received a total of eight injections with oxaliplatin (4 mg/kg), administered at 3-d intervals. TUS intervention (1 MHz, 0.5 W/cm(2)) started on the fifth oxaliplatin administration and continued for 10 consecutive d. Sensory behavioral examinations, protein levels of transient receptor potential channels (TRPM8 and TRPV1) in dorsal root ganglia (DRG) and substance P (SP) in spinal dorsal horn were examined...
April 19, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28433437/optimal-ultrasound-exposure-conditions-for-maximizing-c2c12-muscle-cell-proliferation-and-differentiation
#5
Alice Rita Salgarella, Andrea Cafarelli, Leonardo Ricotti, Lorenzo Capineri, Paolo Dario, Arianna Menciassi
Described here is an in vitro systematic investigation of the effects on C2C12 myoblasts of exposure to finely controlled and repeatable low-intensity pulsed ultrasound of different frequencies (500 kHz, 1 MHz, 3 MHz and 5 MHz) and different intensities (250, 500 and 1000 mW/cm(2)). An in-house stimulation system and an ultrasound-transparent cell culture well minimized reflections and attenuations, allowing precise control of ultrasound delivery. Results indicated that a 3 MHz stimulation at 1 W/cm(2) intensity maximized cell proliferation in comparison with the other exposure conditions and untreated controls...
April 19, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28433436/subharmonic-aided-pressure-estimation-for-monitoring-interstitial-fluid-pressure-in-tumors-calibration-and-treatment-with-paclitaxel-in-breast-cancer-xenografts
#6
Valgerdur G Halldorsdottir, Jaydev K Dave, Andrew Marshall, Anya I Forsberg, Traci B Fox, John R Eisenbrey, Priscilla Machado, Ji-Bin Liu, Daniel A Merton, Flemming Forsberg
Interstitial fluid pressure (IFP) in rats with breast cancer xenografts was non-invasively estimated using subharmonic-aided pressure estimation (SHAPE) versus an invasive pressure monitor. Moreover, monitoring of IFP changes after chemotherapy was assessed. Eighty-nine rats (calibration n = 25, treatment n = 64) were injected with 5 × 10(6) breast cancer cells (MDA-MB-231). Radiofrequency signals were acquired (39 rats successfully imaged) with a Sonix RP scanner (BK Ultrasound, Richmond, BC, Canada) using a linear array (L9-4, transmit/receive: 8/4 MHz) after administration of Definity (Lantheus Medical Imaging, North Billerica, MA, USA; 180 μL/kg) and compared with readings from an invasive pressure monitor (Stryker, Berkshire, UK)...
April 19, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28431795/shear-wave-liver-elastography-with-a-propagation-map-diagnostic-performance-and-inter-observer-correlation-for-hepatic-fibrosis-in-chronic-hepatitis
#7
Eun Sun Lee, Jong Beum Lee, Hwi Ryong Park, Jeongin Yoo, Ji In Choi, Hyun Woong Lee, Hyung Joon Kim, Byung Ihn Choi, Hyun Jeong Park, Sung Bin Park
The aim of this study was to determine the performance of shear wave elastography (SWE) with a propagation map in the diagnosis of hepatic fibrosis, and to assess its reliability with transient elastography (TE) as the reference standard. Our prospective study included 115 consecutive patients with suspected or alleged chronic hepatitis. Patients underwent SWE by two different operators and TE by sonographers on the same day. The correlation coefficient of the intra-class correlation test between an experienced radiologist and a third-year radiology resident was 0...
April 18, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28411966/ultrasound-screening-for-adverse-local-tissue-reaction-after-hip-arthroplasty
#8
David J Robinson, Steven Lee, Paul Marks, Michal E Schneider
Early detection of adverse local tissue reaction (ALTR) to prosthetic hip wear debris is vital to improve the success of revision surgery. Magnetic resonance imaging with metal artefact reduction sequencing (MARS MRI) is considered the modality of choice to provide cross-sectional imaging of the soft tissues. The areas adjacent to the prosthesis are, however, not readily imaged using these protocols. Ultrasound has also been recommended as an imaging modality in the follow-up of hip replacement surgery. We decided to characterise the typical ultrasound findings in a group of patients undergoing routine biennial review of arthroplastic hips with particular reference to the hip capsule, femoral neck and iliopsoas bursa and tendon adjacent to the implant...
April 12, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28411965/dynamic-cerebral-autoregulation-assessment-using-extracranial-internal-carotid-artery-doppler-ultrasonography
#9
Nai-Fang Chi, Hsiao-Lun Ku, Chen-Yen Wang, Yanhui Liu, Lung Chan, Ying-Chin Lin, Chung-Kang Peng, Vera Novak, Han-Hwa Hu, Chaur-Jong Hu
Transcranial Doppler ultrasonography of the middle cerebral artery (MCA) is frequently used to assess dynamic cerebral autoregulation (dCA); however, this is difficult in patients with poor temporal bone windows. In the study described here, we investigated the agreement and sensitivity of dCA indices determined from the extracranial internal carotid artery (ICA) and those determined from the MCA. Measurements for 32 stroke patients and 59 controls were analyzed. Measurement of the mean flow correlation index (Mx) and transfer function analysis based on spontaneous blood pressure fluctuation were simultaneously performed for the extracranial ICA and MCA...
April 12, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28408062/novel-method-for-vessel-cross-sectional-shear-wave-imaging
#10
Qiong He, Guo-Yang Li, Fu-Feng Lee, Qihao Zhang, Yanping Cao, Jianwen Luo
Many studies have investigated the applications of shear wave imaging (SWI) to vascular elastography, mainly on the longitudinal section of vessels. It is important to investigate SWI in the arterial cross section when evaluating anisotropy of the vessel wall or complete plaque composition. Here, we proposed a novel method based on the coordinate transformation and directional filter in the polar coordinate system to achieve vessel cross-sectional shear wave imaging. In particular, ultrasound radiofrequency data were transformed from the Cartesian to the polar coordinate system; the radial displacements were then estimated directly...
April 10, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28408061/predicting-tissue-susceptibility-to-mechanical-cavitation-damage-in-therapeutic-ultrasound
#11
Lauren Mancia, Eli Vlaisavljevich, Zhen Xu, Eric Johnsen
Histotripsy is a developing focused ultrasound procedure that uses cavitation bubbles to mechanically homogenize soft tissue. To better understand the mechanics of tissue damage, a numerical model of single-bubble dynamics was used to calculate stress, strain and strain rate fields produced by a cavitation bubble exposed to a tensile histotripsy pulse. The explosive bubble growth and its subsequent collapse were found to depend on the properties of the surrounding material and on the histotripsy pulse. Stresses far greater than gigapascals were observed close to the bubble wall, but attenuated by four to six orders of magnitude within 50 μm from the bubble wall, with at least two orders of magnitude attenuation occurring within the first 10 μm from the bubble...
April 10, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28400076/can-tumor-to-cortex-echogenicity-ratio-differentiate-angiomyolipomas-from-other-hyper-echoic-renal-masses
#12
Peiman Habibollahi, Anil Chauhan, Laith R Sultan, Lisa P Jones, Chandra M Sehgal
A retrospective study was performed to evaluate the diagnostic value of tumor-to-cortex echogenicity ratio (TCER) in the characterization of hyper-echoic renal masses. The radiology database was queried between 2012 and 2014 for hyper-echoic renal masses on the basis of defined exclusion and inclusion criteria. Each included mass was characterized as either an angiomyolipoma (AML) or a non-AML based on pre-defined criteria. The ratio of renal mass echogenicity to that of adjacent renal cortex (TCER) was calculated for each mass using commercially available software...
April 8, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28395967/carotid-femoral-pulse-wave-velocity-assessed-by-ultrasound-a-study-with-echotracking-technology
#13
Mathieu Collette, Carlo Palombo, Carmela Morizzo, Sara Sbragi, Michaela Kozakova, Georges Leftheriotis
Described here is a new method for determination of carotid-femoral pulse wave velocity (PWV) based on arterial diameter waveform recording by an ultrasound system. The study was carried out on 120 consecutive patients. Carotid-femoral PWV was determined using a tonometric technique (PWVpp, PulsePen, DiaTecne, Milan, Italy) and an echotracking ultrasound system (PWVet, E-Track, Aloka, Tokyo, Japan). The relationship between PWVpp and PWVet was evaluated by linear regression and Bland-Altman analysis. There was excellent agreement between PWVet and PWVpp (Pearson's r = 0...
April 7, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28395966/measurement-of-median-nerve-strain-and-applied-pressure-for-the-diagnosis-of-carpal-tunnel-syndrome
#14
Yuichi Yoshii, Wen-Lin Tung, Tomoo Ishii
The objective of this study was to evaluate the diagnostic utility of strain and applied-pressure measurements of the median nerve in carpal tunnel syndrome (CTS). Thirty-five wrists of 23 idiopathic CTS patients and 30 wrists of 15 normal patients were examined. Median nerve strain, pressure to the skin and the pressure/strain ratio were measured at the proximal carpal tunnel level. Parameters were compared between CTS patients and controls. The areas under the receiver operating characteristic curves (AUCs) were compared for the parameters...
April 7, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28395965/muscular-echovariation-a-new-biomarker-in-amyotrophic-lateral-sclerosis
#15
Jacinto J Martínez-Payá, María Elena Del Baño-Aledo, José Ríos-Díaz, José I Tembl-Ferrairó, Juan F Vázquez-Costa, Francesc Medina-Mirapeix
The purpose of the work described here was to assess the characteristics of echovariation in amyotrophic lateral sclerosis (ALS) compared with other muscle ultrasonography parameters. Twenty-six ALS patients (8 women, mean age 58.9 y, standard deviation 12.02 y) and 26 healthy controls (17 women, mean age 59.6 y, standard deviation 6.41 y) were included in this observational study. They underwent bilateral and transverse ultrasound of the biceps/brachialis, forearm flexor group, quadriceps femoris and tibialis anterior...
April 7, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28395964/inertial-cavitation-ultrasound-with-microbubbles-improves-reperfusion-efficacy-when-combined-with-tissue-plasminogen-activator-in-an-in%C3%A2-vitro-model-of-microvascular-obstruction
#16
Akash Goyal, Francois T H Yu, Mathea G Tenwalde, Xucai Chen, Andrew Althouse, Flordeliza S Villanueva, John J Pacella
We have previously reported that long-tone-burst, high-mechanical-index ultrasound (US) and microbubble (MB) therapy can restore perfusion in both in vitro and in vivo models of microvascular obstruction (MVO). Addition of MBs to US has been found to potentiate the efficacy of thrombolytics on large venous thrombi; however, the optimal US parameters for achieving microvascular reperfusion of MVO caused by microthrombi, when combined with tissue plasminogen activator (tPA), are unknown. We sought to elucidate the specific effects of US, with and without tPA, for effective reperfusion of MVO in an in vitro model using both venous and arterial microthrombi...
April 7, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28392001/nakagami-m-parametric-imaging-for-atherosclerotic-plaque-characterization-using-the-coarse-to-fine-method
#17
Meng Han, Jinjin Wan, Yongfeng Zhao, Xiaodong Zhou, Mingxi Wan
The Nakagami model was used to analyze the statistical differences in ultrasound backscattered signals between different plaque types. To improve image resolution, Nakagami-m parametric imaging using the coarse-to-fine method based on the maximum likelihood estimation (CTF-BOW) was proposed for atherosclerotic plaque characterization. Simulation results confirmed that the CTF-BOW method significantly outperforms the sliding window method in precision, smoothness and resolution. Preliminary in vivo results (n = 45) indicated that the ranges of the m parameters for calcified, mixed and echolucent plaques are, respectively, 0...
April 6, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28392000/swave-imaging-of-placental-elasticity-and-viscosity-proof-of-concept
#18
Jeffrey M Abeysekera, Manyou Ma, Mehran Pesteie, Jefferson Terry, Denise Pugash, Jennifer A Hutcheon, Chantal Mayer, Lutz Lampe, Septimiu Salcudean, Robert Rohling
The placenta is the interface between the fetus and the mother and is vital for fetal development. Ultrasound elastography provides a non-invasive way to examine in vivo the stiffness of the placenta; increased stiffness has previously been linked to fetal growth restriction. This study used a previously developed dynamic elastography method, called shear wave absolute vibro-elastography, to study 61 post-delivery clinically normal placentas. The shear wave speeds in the placenta were recorded under five different low-frequency mechanical excitations...
April 6, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28385471/differentiation-of-inflammatory-from-fibrotic-ileal-strictures-among-patients-with-crohn-s-disease-through-analysis-of-time-intensity-curves-obtained-after-microbubble-contrast-agent-injection
#19
Emilio Quaia, Antonio Giulio Gennari, Edwin J R van Beek
The aim of the study described here was to assess whether the analysis of time-intensity curves obtained after microbubble contrast agent injection could differentiate inflammatory from fibrotic ileal strictures among patients with Crohn's disease. Sixty-five consecutive patients (40 male and 25 female; mean age ± SD, 42.2 ± 12.22 y) with stricture of the terminal ileal loop from Crohn's disease were scanned after microbubble injection. Time-intensity curves were obtained from quantitative analysis, and peak enhancement, rise time, time to peak, area under the time-intensity curve (AUC), AUC during wash-in (AUCWI) and AUC during wash-out (AUCWO) were compared between patients with inflammatory strictures and patients with fibrotic strictures...
April 3, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28385470/cardiac-respiratory-and-postural-influences-on-venous-return-of-internal-jugular-and-vertebral-veins
#20
Maria M Laganà, Marco Di Rienzo, Francesco Rizzo, Cristian Ricci, Sara D'Onofrio, Leonardo Forzoni, Pietro Cecconi
It is known from physiology that heartbeat and respiration influence venous return, but little is known regarding the extent to which these two factors affect flow. In this study, we estimated the prevalence of cardiac- and breathing-induced venous flow modulations in the internal jugular vein (IJV) and vertebral vein (VV) and the effects of posture. In 19 healthy patients, neck vein flow was examined with pulsed wave Doppler. Electrocardiogram and respiratory signals were simultaneously acquired. In supine position, heart contraction always influenced venous flow, whereas breathing influenced 68% of IJV and 34% of VV flow...
April 3, 2017: Ultrasound in Medicine & Biology
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