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Ultrasound in Medicine & Biology

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https://www.readbyqxmd.com/read/28318890/measuring-endotracheal-tube-depth-by-bedside-ultrasound-in-adult-patients-in-an-intensive-care-unit-a-pilot-study
#1
Fenglin Dong, Canhong Zhu, Huiwen Xu, Jiajia Wang, Yehan Zhu, Qingmin Fan, Jian'an Huang, Wei Lei
The aim of the study described here was to evaluate the feasibility and accuracy of measuring endotracheal tube (ETT) depth with ultrasound in adult patients in an intensive care unit (ICU). The distance between the upper margin of the cuff and the upper margin of the aortic arch (Duc-ua) of 67 ICU patients was measured by ultrasound, and the time of measurement was recorded. The level of agreement between the distance between the tip of the ETT and the carina (Dtt-c) measured by ultrasound (U-Dtt-c) and Dtt-c measured by bronchoscopy (B-Dtt-c) was assessed using linear regression and a Bland-Altman plot...
March 16, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28318889/non-invasive-liver-ablation-using-histotripsy-preclinical-safety-study-in-an-in%C3%A2-vivo-porcine-model
#2
Eli Vlaisavljevich, Gabe Owens, Jonathan Lundt, Dejan Teofilovic, Kimberly Ives, Alexander Duryea, Jim Bertolina, Theodore H Welling, Zhen Xu
This study investigates the safety profile for use of histotripsy, a non-invasive ultrasonic ablation method currently being developed for the treatment of liver cancer, for liver ablation in an in vivo porcine model. Histotripsy treatments were applied to the liver and hepatic veins of 22 porcine subjects, with half of the subjects receiving systemic heparinization. Vital signs (heart rate, blood pressure, temperature, electrocardiogram and SpO2) were monitored throughout the procedure and for 1 h post-treatment...
March 16, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28318888/characterization-of-the-lung-parenchyma-using-ultrasound-multiple-scattering
#3
Kaustav Mohanty, John Blackwell, Thomas Egan, Marie Muller
The purpose of the study described here was to showcase the application of ultrasound to quantitative characterization of the micro-architecture of the lung parenchyma to predict the extent of pulmonary edema. The lung parenchyma is a highly complex and diffusive medium for which ultrasound techniques have remained qualitative. The approach presented here is based on ultrasound multiple scattering and exploits the complexity of ultrasound propagation in the lung structure. The experimental setup consisted of a linear transducer array with an 8-MHz central frequency placed in contact with the lung surface...
March 16, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28318887/multi-focus-beamforming-for-thermal-strain-imaging-using-a-single-ultrasound-linear-array-transducer
#4
Man M Nguyen, Xuan Ding, Steven A Leers, Kang Kim
Ultrasound-induced thermal strain imaging (TSI) has been used successfully to identify lipid- and water-based tissues in atherosclerotic plaques in some research settings. However, TSI faces several challenges to be realized in clinics. These challenges include motion artifacts and displacement tracking accuracy, as well as limited heating capability, which contributes to low thermal strain signal-to-noise ratio, and a limited field of view. Our goal was to address the challenge in heating tissue in TSI. Current TSI systems use separate heating and imaging transducers, which require physical alignment of the heating and imaging beams and result in a bulky setup that limits in vivo operation...
March 15, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28285729/evaluation-of-post-stroke-spastic-muscle-stiffness-using-shear-wave-ultrasound-elastography
#5
Chueh-Hung Wu, Yu-Chun Ho, Ming-Yen Hsiao, Wen-Shiang Chen, Tyng-Guey Wang
Current clinical evaluations of post-stroke upper limb spasticity are subjective and qualitative. We proposed a quantitative measurement of post-stroke spastic muscle stiffness by using shear-wave ultrasound elastography and tested its reliability. Acoustic radiation force impulse with shear wave velocity (SWV) detection was used to evaluate stiffness of the biceps brachii muscles at 90° and 0° elbow flexion. In 21 control subjects, SWV did not significantly differ between dominant and non-dominant sides at either flexion angle (0°: p = 0...
March 9, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28283327/pharmacokinetics-of-perfluorobutane-after-intra-venous-bolus-injection-of-sonazoid-in-healthy-chinese-volunteers
#6
Pengfei Li, Susan Hoppmann, Ping Du, Huiling Li, Paul M Evans, Siver A Moestue, Weiyue Yu, Fang Dong, Hongchuan Liu, Lihong Liu
Sonazoid is an ultrasound contrast agent based on microbubbles (MB) containing perfluorobutane (PFB) gas. Sonazoid is approved in Japan, Korea and Norway for contrast-enhanced ultrasonography of focal liver lesions and focal breast lesions (Japan only). The objective of this study was to determine the pharmacokinetics (PKs) and safety of Sonazoid in Chinese healthy volunteers (HVs) and to evaluate the potential for ethnic differences in PKs between Chinese and Caucasian HVs. Sonazoid was administered as an intra-venous bolus injection at the clinical dose of 0...
March 7, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28283326/whole-breast-ultrasound-for-breast-screening-and-archiving
#7
Chiun-Sheng Huang, Ya-Wen Yang, Rong-Tai Chen, Chung-Ming Lo, Chao Lo, Ching-Fen Cheng, Chao-Shuan Lee, Ruey-Feng Chang
The incidence of breast cancer is increasing worldwide, reinforcing the importance of breast screening. Conventional hand-held ultrasound (HHUS) for breast screening is efficient and relatively easy to perform; however, it lacks systematic recording and localization. This study investigated an electromagnetic tracking-based whole-breast ultrasound (WBUS) system to facilitate the use of HHUS for breast screening. One-hundred nine breast masses were collected, and the detection of suspicious breast lesions was compared between the WBUS system, HHUS and a commercial automated breast ultrasound (ABUS) system...
March 7, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28274602/assessment-of-curve-flexibility-on-scoliotic-surgical-candidates-using-ultrasound-imaging-method
#8
Rui Zheng, Doug Hill, Douglas Hedden, Marc Moreau, Lawrence H Le, Jim Raso, Edmond Lou
The ultrasound imaging method was implemented to assess the spinal curve flexibility of scoliotic surgical candidates, or how much correction it can achieve while patients are bending or lying down. Fifteen participants were recruited. Pre-operative radiographs and ultrasound images in both standing and bending positions were acquired. The post-operative standing radiographs were obtained 1 wk after surgery. Two raters (RZ, EL) measured the ultrasound images twice, 1 wk apart. A curve correction index (CI) was developed to estimate the curve flexibility...
March 5, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28268036/effect-of-hypoxemia-on-fetal-ventricular-deformation-in-a-chronically-instrumented-sheep-model
#9
Amarnath Bhide, Juha Rasanen, Heikki Huhta, Juulia Junno, Tiina Erkinaro, Pasi Ohtonen, Mervi Haapsamo, Ganesh Acharya
We hypothesized that in near-term sheep fetuses, hypoxemia changes myocardial function as reflected in altered ventricular deformation on speckle-tracking echocardiography. Fetuses in 21 pregnant sheep were instrumented. After 4 d of recovery, fetal cardiac function was assessed by echocardiography at baseline, after 30 and 120 min of induced fetal hypoxemia and after its reversal. Left (LV) and right (RV) ventricular cardiac output and myocardial strain were measured. Baseline mean (standard deviation [SD]) LV and RV global longitudinal strains were -18...
March 4, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28258771/acoustic-behavior-of-halobacterium-salinarum-gas-vesicles-in-the-high-frequency-range-experiments-and-modeling
#10
Emmanuel Cherin, Johan M Melis, Raymond W Bourdeau, Melissa Yin, Dennis M Kochmann, F Stuart Foster, Mikhail G Shapiro
Gas vesicles (GVs) are a new and unique class of biologically derived ultrasound contrast agents with sub-micron size whose acoustic properties have not been fully elucidated. In this study, we investigated the acoustic collapse pressure and behavior of Halobacterium salinarum gas vesicles at transmit center frequencies ranging from 12.5 to 27.5 MHz. The acoustic collapse pressure was found to be above 550 kPa at all frequencies, nine-fold higher than the critical pressure observed under hydrostatic conditions...
March 1, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28256343/evaluation-of-coronary-artery-disease-using-myocardial-elastography-with-diverging-wave-imaging-validation-against-myocardial-perfusion-imaging-and-coronary-angiography
#11
Julien Grondin, Marc Waase, Alok Gambhir, Ethan Bunting, Vincent Sayseng, Elisa E Konofagou
Myocardial elastography (ME) is an ultrasound-based technique that can image 2-D myocardial strains. The objectives of this study were to illustrate that 2-D myocardial strains can be imaged with diverging wave imaging and differ, on average, between normal and coronary artery disease (CAD) patients. In this study, 66 patients with symptoms of CAD were imaged with myocardial elastography before a nuclear stress test or an invasive coronary angiography. Radial cumulative strains were estimated in all patients...
February 28, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28256344/what-help-could-ultrasound-elastography-give-to-the-diagnosis-of-breast-papillary-lesions
#12
Lu-Jing Li, Ji-Yi Yao, Xin-Chuan Zhou, Xin-Bao Zhao, Wen-Jing Zhong, Bing Ou, Bao-Ming Luo, Shao-Yun Hao, Hui Zhi
On the basis of results of our previous studies and the findings of other scholars, the most common histologic type of false-positive diagnosis with strain elastography (SE) was papilloma. The objectives of our study were to evaluate whether SE could contribute to conventional ultrasound differentiation between benign and malignant papillary lesions and between papillary lesions and other common benign breast lesions. Data on 89 papillary lesions at our hospital, including 74 benign and 15 malignant papillary lesions, were included in our study...
February 27, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28256342/usefulness-of-the-continuous-wave-doppler-derived-pulmonary-arterial-right-ventricular-pressure-gradient-just-before-atrial-contraction-for-the-estimation-of-pulmonary-arterial-diastolic-and-wedge-pressures
#13
Michito Murayama, Taisei Mikami, Sanae Kaga, Kazunori Okada, Takuma Hioka, Nobuo Masauzi, Masahiro Nakabachi, Hisao Nishino, Shinobu Yokoyama, Mutsumi Nishida, Hiroyuki Iwano, Mamoru Sakakibara, Satoshi Yamada, Hiroyuki Tsutsui
In our new echocardiographic method, pulmonary regurgitant velocity immediately before right atrial (RA) contraction is used to estimate pulmonary artery diastolic pressure (PADP) and mean PA wedge pressure (MPAWP). Our aim here was to compare the usefulness of this new method with that of the conventional method, which uses pulmonary regurgitant velocity at end diastole. We studied 55 consecutive patients who underwent echocardiography and right-sided heart catheterization. The pulmonary regurgitant velocities just before RA contraction and at end diastole were measured to obtain echocardiographic estimates of PADP (EPADPpreA and EPADPED, respectively) by adding the pressure gradients to the echocardiographically estimated RA pressure...
February 27, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28242086/ultrasound-image-classification-of-ductal-carcinoma-in-situ-dcis-of-the-breast-analysis-of-705-dcis-lesions
#14
Takanori Watanabe, Takuhiro Yamaguchi, Hiroko Tsunoda, Setsuko Kaoku, Eriko Tohno, Hidemitsu Yasuda, Kanako Ban, Koichi Hirokaga, Kumiko Tanaka, Takeshi Umemoto, Toshitaka Okuno, Yasuhisa Fujimoto, Shuichi Nakatani, Jun Ito, Ei Ueno
The Japan Association of Breast and Thyroid Sonology (JABTS) proposed, in 2003, a conceptual classification system for non-mass abnormalities to be applied in addition to the conventional concept of masses, to facilitate detecting ductal carcinoma in situ (DCIS) lesions. The aim of this study was to confirm the utility of this system and to clarify the distribution of these findings in DCIS lesions. Data on 705 surgically treated DCIS lesions from 16 institutions in Japan were retrospectively reviewed. All 705 DCIS lesions could be classified according to the JABTS classification system...
February 24, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28242085/semi-quantitative-strain-ratio-determined-using-different-measurement-methods-comparison-of-strain-ratio-values-and-diagnostic-performance-using-one-versus-two-region-of-interest-measurement
#15
Jung Hyun Yoon, Mi Kyung Song, Eun-Kyung Kim
We evaluated the agreement and diagnostic performance of strain ratio values using measurements made with one and two user-defined regions of interest (ROIs) on breast elastography. Two hundred forty-three breast masses of 226 women (mean age: 48.2 y) were included. Ultrasonography (US) and elastography images of the masses were recorded. Strain ratio was measured twice on the same elastography image; strain ratio 1, applying one ROI at the target mass for measurement, and strain ratio 2, applying one ROI at the target mass and another ROI as reference strain...
February 24, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28237637/common-carotid-artery-diameter-blood-flow-velocity-and-wave-intensity-responses-at-rest-and-during-exercise-in-young-healthy-humans-a-reproducibility-study
#16
Nicola Pomella, Eurico Nestor Wilhelm Neto Wilhelm, Christina Kolyva, José González-Alonso, Mark Rakobowchuk, Ashraf W Khir
The aim of this study was to assess the reproducibility of non-invasive, ultrasound-derived wave intensity (WI) in humans at the common carotid artery. Common carotid artery diameter and blood velocity of 12 healthy young participants were recorded at rest and during mild cycling, to assess peak diameter, change in diameter, peak velocity, change in velocity, time derivatives, non-invasive wave speed and WI. Diameter, velocity and WI parameters were fairly reproducible. Diameter variables exhibited higher reproducibility than corresponding velocity variables (intra-class correlation coefficient [ICC] = 0...
February 22, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28236534/computer-based-algorithmic-determination-of-muscle-movement-onset-using-m-mode-ultrasonography
#17
Andrew J Tweedell, Courtney A Haynes, Matthew S Tenan
The study purpose was to evaluate the use of computer-automated algorithms as a replacement for subjective, visual determination of muscle contraction onset using M-mode ultrasonography. Biceps and quadriceps contraction images were analyzed visually and with three different classes of algorithms: pixel standard deviation (SD), high-pass filter and Teager Kaiser energy operator transformation. Algorithmic parameters and muscle onset threshold criteria were systematically varied within each class of algorithm...
February 21, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28236532/investigation-of-ultrasound-measured-flow-velocity-flow-rate-and-wall-shear-rate-in-radial-and-ulnar-arteries-using-simulation
#18
Xiaowei Zhou, Chunming Xia, Gandy Stephen, Faisel Khan, George A Corner, Peter R Hoskins, Zhihong Huang
Parameters of blood flow measured by ultrasound in radial and ulnar arteries, such as flow velocity, flow rate and wall shear rate, are widely used in clinical practice and clinical research. Investigation of these measurements is useful for evaluating accuracy and providing knowledge of error sources. A method for simulating the spectral Doppler ultrasound measurement process was developed with computational fluid dynamics providing flow-field data. Specific scanning factors were adjusted to investigate their influence on estimation of the maximum velocity waveform, and flow rate and wall shear rate were derived using the Womersley equation...
February 21, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28233619/sonoelastomics-for-breast-tumor-classification-a-radiomics-approach-with-clustering-based-feature-selection-on-sonoelastography
#19
Qi Zhang, Yang Xiao, Jingfeng Suo, Jun Shi, Jinhua Yu, Yi Guo, Yuanyuan Wang, Hairong Zheng
A radiomics approach to sonoelastography, called "sonoelastomics," is proposed for classification of benign and malignant breast tumors. From sonoelastograms of breast tumors, a high-throughput 364-dimensional feature set was calculated consisting of shape features, intensity statistics, gray-level co-occurrence matrix texture features and contourlet texture features, which quantified the shape, hardness and hardness heterogeneity of a tumor. The high-throughput features were then selected for feature reduction using hierarchical clustering and three-feature selection metrics...
February 20, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28216111/anatomical-regurgitant-orifice-detection-and-quantification-from-3-d-echocardiographic-images
#20
Miguel Sotaquirá, Mauro Pepi, Gloria Tamborini, Enrico G Caiani
The vena contracta and effective regurgitant orifice area (EROA) are currently used for the clinical assessment of mitral regurgitation (MR) from 2-D color Doppler imaging. In addition to being highly user dependent and having low repeatability, these methods do not represent accurately the anatomic regurgitant orifice (ARO), which affects the adequate assessment of MR patients. We propose a novel method for semi-automatic detection and quantitative assessment of the 3-D ARO shape from 3-D transesophageal echocardiographic images...
February 16, 2017: Ultrasound in Medicine & Biology
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