journal
MENU ▼
Read by QxMD icon Read
search

Journal of Comparative Neurology

journal
https://www.readbyqxmd.com/read/28643417/congenital-deafness-affects-deep-layers-in-primary-and-secondary-auditory-cortex
#1
Christoph Berger, Daniela Kühne, Verena Scheper, A Kral
Congenital deafness leads to functional deficits in the auditory cortex for which early cochlear implantation can effectively compensate. Most of these deficits have been demonstrated functionally. Furthermore, the majority of previous studies on deafness have involved the primary auditory cortex; knowledge of higher-order areas is limited to effects of cross-modal reorganization. In this study, we compared the cortical cytoarchitecture of four cortical areas in adult hearing and congenitally deaf cats (CDCs): the primary auditory field A1, two secondary auditory fields, namely the dorsal zone (DZ) and second auditory field (A2); and a reference visual association field (area 7) in the same section stained either using Nissl or SMI-32 antibodies...
June 23, 2017: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/28617951/altered-expression-of-igf-i-system-in-neurons-of-the-inflamed-spinal-cord-during-acute-experimental-autoimmune-encephalomyelitis
#2
Azita Parvaneh Tafreshi, Farideh Talebi, Samira Ghorbani, Claude Bernard, Farshid Noorbakhsh
BACKGROUND: There is growing evidence that the impaired IGF-I system contributes to neurodegeneration. OBJECTIVES: In this study, we examined the spinal cords of the EAE, the animal model of multiple sclerosis, to see if the expression of the IGF-I system is altered. METHODS: To induce EAE, C57/BL6 mice were immunized with the Hooke lab MOG kit, sacrificed at the peak of the disease and their spinal cords were examined for the immunoreactivities (ir) of the IGF-I, IGF binding protein-1 (IGFBP-1) and glycogen synthase kinase 3β (GSK3β), as one major downstream molecule in the IGF-I signaling...
June 15, 2017: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/28614906/heterogeneous-organization-and-connectivity-of-the-chicken-auditory-thalamus-gallus-gallus
#3
Yuan Wang, Diego A R Zorio, Harvey J Karten
The auditory ascending system contains parallel pathways in vertebrate brains. In chickens (Gallus gallus), three pathways arise from nucleus laminaris (NL), nucleus angularis (NA), and regio intermedius (RI) in the brainstem, innervating three subdivisions of the nucleus mesencephalicus lateralis pars dorsalis (MLd) in the midbrain. The current study reveals the segregation of these pathways in their subsequent projections to the nucleus ovoidalis (Ov) in the thalamus. Based on cytoarchitecture and myelin distribution, we identified seven Ov subregions, including five neuronal clusters within the Ov proper, the nucleus semilunaris parovoidalis (SPO), and the circum-ovoidalis (cOv)...
June 14, 2017: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/28608460/anatomical-and-electrophysiological-development-of-the-hypothalamic-orexin-neurons-from-embryos-to-neonates
#4
Yukino Ogawa, Takeshi Kanda, Kaspar Vogt, Masashi Yanagisawa
The amount, quality and diurnal pattern of sleep change greatly during development. Developmental changes of sleep/wake architecture are in a close relationship to brain development. The fragmentation of wake episodes is one of the salient features in the neonatal period, which is also observed in mature animals and human individuals lacking neuropeptide orexin/hypocretin signaling. This raises the possibility that developmental changes of lateral hypothalamic orexin neurons are relevant to the development of sleep/wake architecture...
June 12, 2017: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/28608425/three-dimensional-visualization-of-ocellar-interneurons-of-the-orchid-bee-euglossa-imperialis-using-micro-x-ray-computed-tomography
#5
Willi Ribi, Jochen Zeil
We used contrast-optimized micro X-ray Computed Tomography (mCT) to trace the profiles of the full complement of large ocellar L-neurons in the male orchid bee Euglossa imperialis. We find that most L-neurons collect information from either the dorsal or the ventral retinae in both median and lateral ocelli, with only three neurons associated with the median ocellus having dendritic branches in both dorsal and ventral retina. In the median ocellus, we find also L-neurons that either collect information from the left or the right half of the ocellar plexus and two neurons that have a split dendritic tree in both halves...
June 12, 2017: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/28599354/a-profile-of-auditory-responsive-neurons-in-the-larval-zebrafish-brain
#6
Gilles Vanwalleghem, Lucy A Heap, Ethan K Scott
Many features of auditory processing are conserved among vertebrates, but the degree to which these pathways are established at early stages is not well explored. In this study, we have observed single cell activity throughout the brains of larval zebrafish with the goal of identifying the cellular responses, brain regions, and brain-wide pathways through which these larvae perceive and process auditory stimuli. Using GCaMP and selective plane illumination microscopy, we find strong responses to auditory tones ranging from 100 to 400Hz...
June 9, 2017: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/28597915/dissecting-lsd1-dependent-neuronal-maturation-in-the-olfactory-epithelium
#7
Julie H Coleman, Brian Lin, James E Schwob
Neurons in the olfactory epithelium (OE) each express a single dominant olfactory receptor (OR) allele from among roughly 1000 different OR genes. While monogenic and monoallelic OR expression has been appreciated for over two decades, regulators of this process are still being described; most recently, epigenetic modifiers have been of high interest as silent OR genes are decorated with transcriptionally-repressive trimethylated histone 3 lysine 9 (H3K9me3) whereas active OR genes are decorated with transcriptionally-activating trimethylated histone 3 lysine 4 (H3K4me3)...
June 9, 2017: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/28577305/phenotyping-of-nnos-neurons-in-the-postnatal-and-adult-female-mouse-hypothalamus
#8
Konstantina Chachlaki, Samuel A Malone, Emily Qualls-Creekmore, Erik Hrabovszky, Heike Münzberg, Paolo Giacobini, Fabrice Ango, Vincent Prevot
Neurons expressing nitric oxide (NO) synthase (nNOS) and thus capable of synthesizing NO play major roles in many aspects of brain function. While the heterogeneity of nNOS-expressing neurons has been studied in various brain regions, their phenotype in the hypothalamus remains largely unknown. Here we examined the distribution of cells expressing nNOS in the postnatal and adult female mouse hypothalamus using immunohistochemistry. In both adults and neonates, nNOS was largely restricted to regions of the hypothalamus involved in the control of bodily functions, such as energy balance and reproduction...
June 2, 2017: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/28577301/neural-organization-of-afferent-pathways-from-the-stomatopod-compound-eye
#9
Hanne H Thoen, Nicholas J Strausfeld, Justin Marshall
Crustaceans and insects share many similarities of brain organisation suggesting that their common ancestor possessed some components of those shared features. Stomatopods (mantis shrimps) are basal eumalacostracan crustaceans famous for their elaborate visual system, the most complex of which possesses 12 types of colour photoreceptors and the ability to detect both linearly and circularly polarised light. Here, using a palette of histological methods we describe neurons and their neuropils most immediately associated with the stomatopod retina...
June 2, 2017: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/28560734/substrate-properties-of-zebrafish-rtn4b-nogo-and-axon-regeneration-in-the-zebrafish-optic-nerve
#10
Vsevolod Bodrikov, Cornelia Welte, Marianne Wiechers, Markus Weschenfelder, Gurjot Kaur, Aleksandra Shypitsyna, Alejandro Pinzon-Olejua, Martin Bastmeyer, Claudia A O Stuermer
This study explored why lesioned retinal ganglion cell (RGC) axons regenerate successfully in the zebrafish optic nerve despite the presence of Rtn4b, the homologue of the rat neurite growth inhibitor RTN4-A/Nogo-A. Rat Nogo-A and zebrafish Rtn4b possess characteristic motifs (M1-4) in the Nogo-A-specific region, which contains delta20, the most inhibitory region of rat Nogo-A. To determine whether zebrafish M1-4 is inhibitory as rat M1-4 and Nogo-A delta20, proteins were recombinantly expressed and used as substrates for zebrafish single cell RGCs, mouse hippocampal neurons and goldfish, zebrafish and chick retinal explants...
May 30, 2017: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/28560719/visual-system-pathology-in-humans-and-animal-models-of-blast-injury
#11
REVIEW
Gloria J DeWalt, William D Eldred
Injury from blast exposure is becoming a more prevalent cause of death and disability worldwide. The devastating neurological impairments that result from blasts are significant and lifelong. Progress in the development of effective therapies to treat injury have been slowed by its heterogeneous pathology and the dearth of information regarding the cellular mechanisms involved. Within the last decade, a number of studies have documented visual dysfunction following injury. This brief review examines blast damage to the visual system in both humans and animal models of blast injury...
May 30, 2017: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/28547795/synaptogenesis-and-synaptic-protein-localization-in-the-postnatal-development-of-rod-bipolar-cell-dendrites-in-mouse-retina
#12
Ivan A Anastassov, Weiwei Wang, Felice A Dunn
Retinal responses to photons originate in rod photoreceptors and are transmitted to the ganglion cell output of the retina through the primary rod bipolar pathway. At the first synapse of this pathway, input from multiple rods is pooled into individual rod bipolar cells. This architecture is called convergence. Convergence serves to improve sensitivity of rod vision when photons are sparse. Establishment of convergence depends on the development of a proper complement of dendritic tips and transduction proteins in rod bipolar cells...
May 25, 2017: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/28542916/spatial-rearrangement-of-purkinje-cell-subsets-forms-the-transverse-and-longitudinal-compartmentalization-in-the-mouse-embryonic-cerebellum
#13
Suteera Vibulyaseck, Hirofumi Fujita, Yuanjun Luo, Anh Khoa Tran, Arata Oh-Nishi, Yuichi Ono, Shinji Hirano, Izumi Sugihara
Transversely oriented lobules and longitudinally arrayed stripes of Purkinje cell subsets subdivide the cerebellar cortex into multiple compartments that are involved in diverse functions. In the mammalian cerebellum, anterior, and posterior lobules, which are involved in somatosensorimotor function, show an alternation of aldolase C (zebrin II) -positive and -negative stripes, whereas the central lobules (lobules VIb-VII and crus I), which are implicated in nonmotor functions, show a laterally expanded arrangement solely of aldolase C-positive stripes...
May 24, 2017: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/28542900/the-sensory-trigeminal-complex-and-the-organization-of-its-primary-afferents-in-the-zebra-finch-taeniopygia-guttata
#14
Macarena Faunes, J Martin Wild
Our knowledge of the avian sensory trigeminal system has been largely restricted to the principal trigeminal nucleus (PrV) and its ascending projections to the forebrain. Studies addressing the cytoarchitecture and organization of afferent input to the sensory trigeminal complex, which includes both the PrV and the nuclei of the descending trigeminal tract (nTTD), have only been performed in pigeons and ducks. Here we extend such an analysis to a songbird, the zebra finch (Taeniopygia guttata). We describe the cytoarchitecture of the sensory trigeminal complex, the patterns of calbindin-like and substance P-like immunoreactivity, and the organization of afferents from the three branches of the trigeminal nerve and from the lingual branch of the hypoglossal nerve...
May 24, 2017: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/28543449/the-ascending-projections-of-the-nuclei-of-the-descending-trigeminal-tract-nttd-in-the-zebra-finch-taeniopygia-guttata
#15
Macarena Faunes, J Martin Wild
In our traditional view of the avian somatosensory system, input from the beak and head reaches the telencephalon via a disynaptic pathway, involving projections from the principal sensory nucleus (PrV) directly to nucleus basorostralis (previously called nucleus basalis), whereas input from the rest of the body follows a trisynatic pathway similar to that in mammals, involving projections from the dorsal column nuclei to the thalamus, and thence to somatosensory cortex. However, the role of the nuclei of the descending trigeminal tract (nTTD) in this scenario is unclear, partly because their ascending projections have been examined in only one species, the mallard duck (Arends & Dubbeldam, 1984, Neuroscience 13(3):797-817)...
May 23, 2017: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/28543083/afferent-and-efferent-projections-of-the-anterior-cortical-amygdaloid-nucleus-in-the-mouse
#16
Bernardita Cádiz-Moretti, María Abellán-Álvaro, Cecília Pardo-Bellver, Fernando Martínez-García, Enrique Lanuza
The anterior cortical amygdaloid nucleus (ACo) is a chemosensory area of the cortical amygdala that receives afferent projections from both the main and accessory olfactory bulbs. The role of this structure is unknown, partially due to a lack of knowledge of its connectivity. In this work, we describe the pattern of afferent and efferent projections of the ACo by using fluorogold and biotinylated dextranamines as retrograde and anterograde tracers, respectively. The results show that the ACo is reciprocally connected with the olfactory system and basal forebrain, as well as with the chemosensory and basomedial amygdala...
May 23, 2017: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/28543060/nogo-b-is-the-major-form-of-nogo-at-the-floor-plate-and-likely-mediates-crossing-of-commissural-axons-in-the-mouse-spinal-cord
#17
Liqing Wang, Chao Yu, Jun Wang, Peggy Leung, Ding Ma, Hui Zhao, Jeremy S H Taylor, Sun-On Chan
Using Nogo antibodies with defined binding specificity, Nogo-B, but not Nogo-A, was localized on radial glia in the floor plate of mouse embryos. The presence of Nogo-B was confirmed in Nogo-A knockout mice. In explant cultures of embryonic day (E) 11 and E12 spinal cord, blocking of NgR function with antagonist peptide NEP1-40 reduced the crossing of newly arrived commissural axons, resulting in an accumulation of growth cones in the floor plate. Analysis of growth cone morphology demonstrated an increase in size of growth cones in the floor plate after peptide treatment, which was not detected in axons growing towards the midline...
May 22, 2017: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/28543879/vglut1-synapses-and-p-boutons-on-regenerating-motoneurons-after-nerve-crush
#18
Adam J Schultz, Travis M Rotterman, Anirudh Dwarakanath, Francisco J Alvarez
Stretch-sensitive Ia afferent monosynaptic connections with motoneurons form the stretch reflex circuit. After nerve transection, Ia afferent synapses and stretch reflexes are permanently lost, even after regeneration and efficient re-innervation of muscle by motor and sensory afferents is completed in the periphery. This loss greatly affects full recovery of motor function. However, after nerve crush, reflex muscle forces during stretch do recover after muscle reinnervation and reportedly exceed 140% baseline values...
May 20, 2017: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/28542922/study-of-retinal-neurodegeneration-and-maculopathy-in-diabetic-meriones-shawi-a-particular-animal-model-with-human-like-macula
#19
Imane Hammoum, Maha Benlarbi, Ahmed Dellaa, Klaudia Szabó, Bulcsú Dékány, Dávid Csaba, Zsuzsanna Almási, Rozina I Hajdú, Rached Azaiz, Ridha Charefeddine, Ákos Lukáts, Rafika Benchouacha-Chekir
The purpose of this work was to evaluate a potentially useful animal model, Meriones shawi (M.sh) - developing metabolic X syndrome, diabetes and possessing a visual streak similar to human macula - in the study of diabetic retinopathy and diabetic macular edema (DME). Type 2 diabetes (T2D) was induced by high fat diet administration in M.sh. Body weights, blood glucose levels were monitored throughout the study. Diabetic retinal histopathology was evaluated 3 and 7 months after diabetes induction. Retinal thickness was measured, retinal cell types were labeled by immunohistochemistry and the number of stained elements were quantified...
May 20, 2017: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/28512739/normal-develompent-of-spinal-axons-in-early-embryo-stages-and-posterior-locomotor-function-is-independent-of-gal-1
#20
Juana M Pasquini, Francisco J Barrantes, Héctor R Quintá
It was recently described that Galectin-1 (Gal-1) promotes axonal growth after spinal cord injury. This effect depends on protein dimerization, since monomeric Gal-1 fails to stimulate axonal re-growth. Gal-1 is expressed in vivo at concentrations that favor the monomeric species. The aim of the present study is to investigate whether endogenous Gal-1 is required for spinal axon development and normal locomotor behavior in mice. In order to characterize axonal development, we used a novel combination of 3-DISCO technique with 1-photon microscopy and epifluorescence microscopy under high power LED illumination, followed by serial image section deconvolution and 3-D reconstruction...
May 17, 2017: Journal of Comparative Neurology
journal
journal
24459
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"