journal
MENU ▼
Read by QxMD icon Read
search

Survey of Ophthalmology

journal
https://www.readbyqxmd.com/read/28688894/a-review-of-keratoconus-diagnosis-pathophysiology-and-genetics
#1
V Mas-Tur, C MacGregor, R Jayaswal, D P S O'Brart, N J R Maycock
We discuss new approaches to the early detection of keratoconus (KCN) and recent investigations regarding the nature of its pathophysiology. We review the current evidence for its complex genetics and evaluate the presently identified genes/loci and potential candidate gene/loci. In addition, we highlight current research methodologies that may be used to further elucidate the pathogenesis of KCN.
July 5, 2017: Survey of Ophthalmology
https://www.readbyqxmd.com/read/28684101/acquired-unilateral-scotoma
#2
Amir H Marvasti, Kevin C Chen, Henry A Ferreyra, Julie Falardeau
A 54-year-old white man presented with a "blind spot" temporally in his left eye. Best-corrected visual acuity in the affected eye was 20/20 and Humphrey visual field revealed an enlarged blind spot. Funduscopic examination revealed subtle peripapillary pigmentary changes corresponding to a well-demarcated peripapillary region of hyper- and hypoautofluorescence on fundus autofluorescence (FAF). Outer retinal degenerative changes were detected on spectral domain optical coherence tomography (SD-OCT). A diagnosis of Acute zonal occult outer retinopathy (AZOOR) was made based on clinical history and imaging studies...
July 3, 2017: Survey of Ophthalmology
https://www.readbyqxmd.com/read/28673727/central-serous-chorioretinopathy-and-glucocorticoids-an-update-on-evidence-for-association
#3
REVIEW
Benjamin P Nicholson, Elizabeth Atchison, Amrou Ali Idris, Sophie J Bakri
Central serous chorioretinopathy (CSC) is a common idiopathic retinal disease characterized by central vision loss from serous detachment of the neurosensory retina, serous pigment epithelial detachments, and leakage of fluid through the retinal pigment epithelium into the sub-retinal space. The concept of an association between exogenous glucocorticoid use and CSC is widely accepted among ophthalmologists. Here we review the evidence for and against such an association. This evidence includes two large, case-control studies that found strong associations, and a smaller, population-based study that found no association...
June 30, 2017: Survey of Ophthalmology
https://www.readbyqxmd.com/read/28666629/ageing-and-ocular-tissue-stiffness-in-glaucoma
#4
REVIEW
Baiyun Liu, Sara McNally, Jason I Kilpatrick, Suzanne P Jarvis, Colm J O'Brien
Glaucoma is a progressive and chronic neurodegenerative disorder characterised by damage to the inner layers of the retina and deformation of the optic nerve head. The degeneration of retinal ganglion cells (RGCs) and their axons results in an irreversible loss of vision and is correlated with increasing age. Extracellular matrix (ECM) changes related to natural ageing generates a stiffer extracellular environment throughout the body. Altered age-associated ocular tissue stiffening plays a major role in a significant number of ophthalmic pathologies...
June 27, 2017: Survey of Ophthalmology
https://www.readbyqxmd.com/read/28648383/optical-coherence-tomography-angiography-in-dry-age-related-macular-degeneration
#5
REVIEW
Maria Vittoria Cicinelli, Alessandro Rabiolo, Riccardo Sacconi, Adriano Carnevali, Lea Querques, Francesco Bandello, Giuseppe Querques
Optical coherence tomography angiography (OCT-A) is a new imaging modality that provides non-invasive characterization and quantification of the microvasculature in different retinal conditions. The purpose of this paper is to give an updated review of the features of dry age-related macular degeneration investigated by means of new generation OCT-A. We searched PubMed and Medline using the terms "optical coherence tomography angiography" associated with "age-related macular degeneration", "drusen", "reticular pseudodrusen," and "geographic atrophy" and reviewed publications up to January, 2017...
June 22, 2017: Survey of Ophthalmology
https://www.readbyqxmd.com/read/28624250/reply-to-lee-et-al-viral-posterior-uveitis
#6
LETTER
Dr Paul J Steptoe
No abstract text is available yet for this article.
June 14, 2017: Survey of Ophthalmology
https://www.readbyqxmd.com/read/28623165/ocular-effects-of-zika-virus-a-review
#7
REVIEW
Maria Carolina Marquezan, Camila V Ventura, Jeanne S Sheffield, William Christopher Golden, Revaz Omiadze, Rubens Belfort, William May
Zika virus (ZIKV) was considered an innocent pathogen while restricted to the African and Asian population; however, after reaching the Americas in March 2015, it became a global threat. Despite usually causing mild or no symptoms in infected adults, ZIKV displays a different behavior towards fetuses. When infected during gestation, fetuses have their immature neural cells killed by the virus and consequently have devastating findings at birth. In the past year, the drastic effects of ZIKV infection in newborns include neurological, ophthalmological, audiological, and skeletal abnormalities...
June 13, 2017: Survey of Ophthalmology
https://www.readbyqxmd.com/read/28623164/thick-corneas-large-pupils-and-a-giant-problem
#8
Francesco Pellegrini, Giovanni Prosdocimo, Daniela Bonsanto, Rod Foroozan
An 87-year-old woman presented 1 month after uneventful cataract surgery with ipsilateral corneal edema. She was diagnosed with pseudophakic bullous keratopathy and scheduled for endothelial transplantation. However, a few days later, she presented with bilateral corneal edema, dilated pupils and further reduction of visual acuity. Neuro-Ophthalmic evaluation disclosed a bilateral ocular ischemic syndrome causing complete visual loss. Temporal artery biopsy was consistent with GCA. Corneal decompensation should be considered as a rare presentation of GCA, that ophthalmologists should suspect in any case of unilateral or bilateral ocular ischemic syndrome...
June 13, 2017: Survey of Ophthalmology
https://www.readbyqxmd.com/read/28606632/author-s-response
#9
LETTER
Rupesh Agrawal
No abstract text is available yet for this article.
June 9, 2017: Survey of Ophthalmology
https://www.readbyqxmd.com/read/28579550/the-application-of-optical-coherence-tomography-angiography-in-retinal-diseases
#10
REVIEW
Kumar Sambhav, Sandeep Grover, K V Chalam
Optical coherence tomography angiography (OCTA) is a new, non-invasive imaging technique that generates real time volumetric data of chorioretinal vasculature and its flow pattern. With the advent of high-speed optical coherence tomography, established en-face chorioretinal segmentation, and efficient algorithms, OCTA generate images that resembles an angiogram. The principle of OCTA involves determining the change in backscattering between consecutive B-scans and then attributing the differences to the flow of erythrocytes through retinal blood vessels...
June 1, 2017: Survey of Ophthalmology
https://www.readbyqxmd.com/read/28579549/the-use-of-microperimetry-in-assessing-visual-function-in-age-related-macular-degeneration
#11
REVIEW
Nicola K Cassels, John M Wild, Tom H Margrain, Victor Chong, Jennifer H Acton
Microperimetry is a novel technique for assessing visual function and appears particularly suitable for age-related macular degeneration (AMD). Compared to standard automated perimetry (SAP), microperimetry offers several unique features. It simultaneously images the fundus, incorporates an eye tracking system to correct the stimulus location for fixation loss, and identifies any preferred retinal loci. A systematic review of microperimetry in the assessment of visual function in AMD identified 680 articles...
June 1, 2017: Survey of Ophthalmology
https://www.readbyqxmd.com/read/28533131/don-t-get-off-the-track
#12
Rod Foroozan, Andrew G Lee
A 43 year-old man noted decreased vision after head trauma, with normal neuroimaging acutely. He had a left homonymous hemianopia, confirmed with hemifield visual evoked potentials, from trauma to the right optic tract. Four months after trauma an MRI of the brain showed atrophy of the right optic tract, and funduscopy revealed optic disc pallor with decreased retinal nerve fiber layer measures consistent with an optic tract syndrome.
May 19, 2017: Survey of Ophthalmology
https://www.readbyqxmd.com/read/28527856/a-bloody-mess
#13
Michael C Brodsky, Valérie Biousse
A 15-year-old girl presented with a unilateral sixth nerve palsy and papilledema following a severe headache. MR imaging showed thrombosis of the superior sagittal sinus and proximal right transverse sinus that were attributed to oral contraceptive use after a coagulation workup was negative. Systemic anticoagulation caused a hemorrhagic papillopathy in both eyes, raising the question as to whether anticoagulation should be discontinued. Diagnostic and management issues regarding cerebral venous sinus thrombosis with secondary intracranial hypertension are discussed...
May 17, 2017: Survey of Ophthalmology
https://www.readbyqxmd.com/read/28522341/systemic-and-ocular-fluid-compounds-as-potential-biomarkers-in-age-related-macular-degeneration
#14
REVIEW
Eveline Kersten, Constantin C Paun, Rosa L Schellevis, Carel B Hoyng, Cécile Delcourt, Imre Lengyel, Tunde Peto, Marius Ueffing, Caroline C W Klaver, Sascha Dammeier, Anneke I den Hollander, Eiko K de Jong
Biomarkers can help unravel mechanisms of disease and identify new targets for therapy. They can also be useful in clinical practice for monitoring disease progression, evaluation of treatment efficacy and risk assessment in multifactorial diseases, such as age-related macular degeneration (AMD). AMD is a highly prevalent progressive retinal disorder for which multiple genetic and environmental risk factors have been described, but the exact etiology is not yet fully understood. Many compounds have been evaluated for their association with AMD...
May 15, 2017: Survey of Ophthalmology
https://www.readbyqxmd.com/read/28506604/the-supraciliary-space-as-a-suitable-pathway-for-glaucoma-surgery-ho-hum-or-home-run
#15
REVIEW
Michele Figus, Chiara Posarelli, Andrea Passani, Timothy G Albert, Francesco Oddone, Angela Tindara Sframeli, Marco Nardi
The supraciliary space is a physiological route for aqueous humor outflow located anteriorly between the outer surface of the ciliary body and the internal surface of the sclera. Posteriorly, the suprachoroidal space is located between the choroid and the internal surface of the sclera. These spaces have been targeted as suitable and helpful pathways for glaucoma treatment, alternatives to the traditional subconjunctival space. The subconjunctival surgical pathway is affected by several limitations such as poor cosmesis, a lifetime risk for endophthalmitis, and an unpredictable wound healing response...
May 12, 2017: Survey of Ophthalmology
https://www.readbyqxmd.com/read/28506603/exudative-retinal-detachment
#16
REVIEW
Radgonde Amer, Hilal Nalcı, Nilüfer Yalçındağ
Exudative retinal detachment (ERD) develops when fluid collects in the subretinal space. The subretinal space between the photoreceptors and the retinal pigment epithelium is the remnant of the embryonic optic vesicle. In the developed eye the subretinal space is of minimal size, but it can re-open under pathological conditions that disrupt the integrity of blood-retinal barrier (BRB). Inflammatory, infectious, infiltrative, neoplastic, vascular and degenerative conditions may be associated with BRB breakdown and the sequential development of ERD...
May 12, 2017: Survey of Ophthalmology
https://www.readbyqxmd.com/read/28336128/retinal-pigment-epithelium-tears-classification-pathogenesis-predictors-and-management
#17
REVIEW
Mehmet Giray Ersoz, Murat Karacorlu, Serra Arf, Isil Sayman Muslubas, Mumin Hocaoglu
Various eye conditions cause tears in the retinal pigment epithelium (RPE). The most common cause of a RPE tear is vascularized retinal pigment epithelial detachment (PED) in patients with exudative age-related macular degeneration. Although RPE tears can develop spontaneously in vascularized PEDs, most recent cases have been associated with anti-vascular endothelial growth factor (VEGF) injections. The subretinal fluid within the PED applies hydrostatic pressure to the RPE and stretches it. The PED enlarges as the hydrostatic pressure increases...
July 2017: Survey of Ophthalmology
https://www.readbyqxmd.com/read/28300548/new-insights-into-the-pathoanatomy-of-macular-holes-based-on-features-of-optical-coherence-tomography
#18
REVIEW
Hyewon Chung, Suk Ho Byeon
Various important findings related to the development and progression of idiopathic macular holes (MHs) have been described using optical coherence tomography since Gass first staged MH development using biomicroscopy in 1988 and 1995. We believe that a system for classifying and staging MHs should reflect the degree of disease status and its progression and have value not only from a practical point of view (by predicting the chance of closure or visual recovery), but also provide researchers and clinicians with insights into the pathogenesis and disease progression of MH...
July 2017: Survey of Ophthalmology
https://www.readbyqxmd.com/read/28189495/retinal-angiomatous-proliferation
#19
REVIEW
Andrew S H Tsai, Ning Cheung, Alfred T L Gan, Glenn J Jaffe, Sobha Sivaprasad, Tien Yin Wong, Chui Ming Gemmy Cheung
Retinal angiomatous proliferation (RAP) is a unique variant of neovascular age-related macular degeneration. Published studies have estimated that up to 15% of patients with neovascular age-related macular degeneration have RAP. Clinical features frequently associated with RAP include bilateral disease, presence of pigment epithelial detachments, and reticular pseudodrusen. RAP is more frequently associated with the development of retinal pigment epithelial tears and geographic atrophy that can lead to severe vision loss...
July 2017: Survey of Ophthalmology
https://www.readbyqxmd.com/read/28131871/cavernous-venous-malformation-cavernous-hemangioma-of-the-orbit-current-concepts-and-a-review-of-the-literature
#20
REVIEW
Luigi Calandriello, Gabriela Grimaldi, Gianluigi Petrone, Mario Rigante, Sergio Petroni, Monica Riso, Gustavo Savino
The cavernous venous malformation of the orbit, previously called cavernous hemangioma, is the most common primary orbital lesion of adults. Cavernous venous malformation occurs more often in women and typically presents in the fourth and fifth decades of life. It is a benign vascular malformation characterized by a well-defined capsule and numerous large vascular channels. The most common sign of cavernous venous malformation is progressive axial proptosis from the preferential involvement of the intraconal orbital space...
July 2017: Survey of Ophthalmology
journal
journal
24417
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"