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Southern Medical Journal

Abdelhamid M Alsharif, Michelle Potts, Regina Laws, Amado X Freire, Ibrahim Sultan-Ali
OBJECTIVES: Obstructive sleep apnea (OSA) is a prevalent disorder that is associated with multiple medical consequences. Although in-laboratory polysomnography is the gold standard for the diagnosis of OSA, portable monitors have been developed and studied to help increase efficiency and ease of diagnosis. We aimed to assess the adequacy of a midlevel provider specializing in sleep medicine to risk-stratify patients for OSA based on a chart review versus a comprehensive clinic evaluation before scheduling an unattended sleep study...
October 2016: Southern Medical Journal
Eliana Hanna Deschamps, Elias B Hanna
An atrioventricular accessory pathway (AP) may be manifest or concealed. When manifest, it leads to preexcitation on the baseline electrocardiogram, which is called the Wolff-Parkinson-White pattern. The degree of preexcitation varies according to the relative conduction speed of the atrioventricular node versus the AP, the AP location, and the AP refractory period. This explains that even a manifest AP may lead to only intermittent preexcitation. The AP conducts faster than the atrioventricular node but has a longer refractory period, which allows the initiation of a reentrant arrhythmia called atrioventricular reciprocating tachycardia...
October 2016: Southern Medical Journal
Michael G Abraham
No abstract text is available yet for this article.
October 2016: Southern Medical Journal
James E Siegler, Sheryl Martin-Schild
INTRODUCTION: Although intravenous tissue plasminogen activator (IV tPA) is associated with neurologic deterioration (ND) caused by hemorrhage, whether it attenuates deterioration as a result of other etiologies including progressive stroke remains unexplored. The objective of this study was to determine whether IV tPA is associated with a reduced risk of ND caused by progressive stroke. METHODS: A retrospective investigation of consecutively admitted patients with acute ischemic stroke (July 2008-June 2014) within 4...
October 2016: Southern Medical Journal
Kriselle Lao, Namita Sharma, Ajeet Gajra, Neerja Vajpayee
OBJECTIVE: The purpose of this study was to correlate the significance of bone marrow hemophagocytosis and analyze outcome data in patients with suspected hemophagocytic lymphohistiocytosis (HLH) at a tertiary care hospital during the course of 5 years. METHODS: The pathology database of State University of New York Upstate Medical University, Syracuse, was searched for the terms "hemophagocytosis," "hemophagocytic syndrome," and "hemophagocytic lymphohistiocytosis" encompassing the period January 2009-December 2014...
October 2016: Southern Medical Journal
Adam C Adler
No abstract text is available yet for this article.
October 2016: Southern Medical Journal
Chris Terpening
Allergies to various antibiotics are reported by a substantial proportion of patients. As a result, clinical decision support programming generates frequent warnings when prescribing within electronic medical records. For a variety of reasons, the majority of these warnings may be inappropriate. Our improved understanding of the underlying physiology of allergic processes reveals that the majority of cross-reacting antibiotic allergies are implausible. Appropriate history taking and workup can invalidate many more warnings...
October 2016: Southern Medical Journal
Rita Pichardo-Geisinger
No abstract text is available yet for this article.
October 2016: Southern Medical Journal
William B Horton, Patrick L Boler, Angela R Subauste
Diabetes mellitus (DM) is a heterogeneous condition characterized by hyperglycemia as a consequence of defects in insulin secretion and variable degrees of insulin resistance. DM is the most common endocrine disorder in the United States, affecting 9.3% of the population (29.1 million people) in 2014. Skin disorders are present in 79.2% of patients with DM, and cutaneous disease may appear as the first sign of DM or develop at any time in the course of the disease. Given the increasing incidence and prevalence of DM in the United States, primary care physicians should be aware of the associated cutaneous manifestations...
October 2016: Southern Medical Journal
Lindsay D Croft, Michael E Liquori, James Ladd, Hannah R Day, Lisa Pineles, Elizabeth M Lamos, Preeti Mehrotra, Eli N Perencevich, Anthony D Harris, Daniel J Morgan
OBJECTIVES: Adverse events (AEs) are unintended physical injuries resulting from or contributed to by medical or surgical care. We determined the frequency and type of AEs before, during, and after hospital admission. METHODS: We conducted a cohort study of 296 adult hospital patients. We used the standardized Institute for Healthcare Improvement Global Trigger Tool for Measuring Adverse Events to review the medical records of the hospital patients for occurrence, timing relative to hospital admission, severity, and preventability of AEs...
October 2016: Southern Medical Journal
Puneet Narang, Amy Johnson, Manasa Enja, Steven Lippmann
Many psychiatric patients experience pharmaceutical intolerances, and some of them do not derive optimal efficacy from their pharmacotherapies. Clinical problems such as these may result in prolonged dysfunction, adverse consequences, and repeated changes in medication treatment regimens. Pharmacogenomics is a laboratory method that aids individualized medication selection by predicting drug efficacy and adverse effect profiles. It is a technique that involves the testing of patients' genetic makeup to improve medicinal response and tolerance...
October 2016: Southern Medical Journal
Kyle E Horst, Susan C Modesitt
OBJECTIVES: Endometrial cancer remains the fourth most common malignancy among US women, and hormonal contraceptives drastically reduce this risk. The study objectives were to assess the prescribing patterns, counseling practices, and knowledge of family physicians and obstetrician/gynecologists (OB/GYNs) regarding hormonal contraceptives, obesity, and cancer prevention. METHODS: A 25-question survey was mailed to 4600 OB/GYNs and family practitioners licensed in Virginia to assess self-reported hormonal contraceptive prescription practices, patient evaluation and counseling, and gynecologic oncology knowledge...
October 2016: Southern Medical Journal
G Richard Holt
No abstract text is available yet for this article.
October 2016: Southern Medical Journal
Anna N Breiburg, Ware Kuschner
No abstract text is available yet for this article.
October 2016: Southern Medical Journal
James R Churilla, Tammie M Johnson, Michael R Richardson, Bethany D Williams
OBJECTIVES: Examine the odds of adults reporting physical inactivity (PI) across six body mass index (BMI) categories. METHODS: We used data from the 2013 Behavioral Risk Factor Surveillance System. Six BMI categories were used. RESULTS: The odds of reporting PI in underweight men and men in the class I, II, and III obesity categories were 1.65 (95% confidence interval [CI] 1.35-2.02), 1.30 (95% CI 1.21-1.39), 1.73 (95% CI 1.58-1.90), and 2...
October 2016: Southern Medical Journal
Catherine Bulka, Loretta J Nastoupil, Jean L Koff, Leon Bernal-Mizrachi, Kevin C Ward, Jessica N Williams, A Rana Bayakly, Jeffrey M Switchenko, Lance A Waller, Christopher R Flowers
OBJECTIVES: Examining the spatial patterns of diffuse large B-cell lymphoma (DLBCL) incidence and residential proximity to toxic release locations may provide insight regarding environmental and sociodemographic risk factors. METHODS: We linked and geocoded cancer incidence data for the period 1999-2008 from the Georgia Comprehensive Cancer Registry with population data from the US Census and the Environmental Protection Agency's Toxics Release Inventory. We conducted cluster analyses and constructed Poisson regression models to assess DLBCL incidence as a function of mean distance to the toxic release sites...
October 2016: Southern Medical Journal
Kristen Ranzenberger, Terry L Bunn, Svetla Slavova
OBJECTIVES: The healthcare industry continues to have a high number of reported injuries. The purpose of this study was to characterize healthcare industry injuries by patient contact status, identify the occupations associated with healthcare injuries by patient contact status, and determine healthcare injury rates by occupation to gain a better understanding of healthcare industry-compensated injuries and better target safety practices and programs in the healthcare industry. METHODS: Kentucky healthcare industry workers' compensation first reports of injuries from calendar years 2012-2014 were categorized into injuries involved in direct patient contact versus injuries without direct patient contact using narrative text analysis...
October 2016: Southern Medical Journal
Ramin Parsa-Parsi
No abstract text is available yet for this article.
October 2016: Southern Medical Journal
Edward Donnell Ivy
No abstract text is available yet for this article.
September 2016: Southern Medical Journal
Lance A Williams, Robin G Lorenz, Absar Tahir, Huy P Pham, Marisa B Marques
OBJECTIVES: Alloantibody formation secondary to transfusion in patients with sickle cell disease (SCD) is a well-known phenomenon. Pretransfusion testing (eg, "antibody screening") protects patients from receiving incompatible red blood cell transfusions. Because alloantibodies have a tendency to evanesce (ie, become undetectable over time), however, this phenomenon puts patients at risk of a delayed hemolytic transfusion reaction or even acute hemolysis. METHODS: We evaluated the records of 71 patients with SCD with alloantibodies detected during a 2-year period to describe their most common specificities and their rate of evanescence...
September 2016: Southern Medical Journal
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