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Singapore Medical Journal

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https://www.readbyqxmd.com/read/29430577/phenotypic-and-metabolic-dichotomy-in-obesity-clinical-biochemical-and-immunological-correlates-of-metabolically-divergent-obese-phenotypes-in-healthy-south-asian-adults
#1
Khadija Irfan Khawaja, Saqib Ali Mian, Aziz Fatima, Ghulam Murtaza Tahir, Fehmida Farrukh Khan, Saira Burney, Ali Hasan, Faisal Masud
INTRODUCTION: Metabolic heterogeneity among obese individuals is thought to translate into variation in cardiovascular risk. Identifying obese people with an unfavourable metabolic profile may allow targeting preventive strategies towards those at greatest risk. This study aimed to identify clinical, biochemical and immunological differences between insulin sensitive and resistant obese subgroups, to understand the population-specific pathophysiological basis of the adverse cardiovascular risk profile in the latter group...
February 12, 2018: Singapore Medical Journal
https://www.readbyqxmd.com/read/29430576/prevalence-and-correlates-of-diabetes-mellitus-and-dyslipidaemia-in-a-long-stay-inpatient-schizophrenia-population-in-singapore
#2
Saleha Shafie, Siau Pheng Lee, Samantha Bee Cheng Ong, Peizhi Wang, Esmond Seow, Hui Lin Ong, Siow Ann Chong, Mythily Subramaniam
INTRODUCTION: Patients with schizophrenia have shorter life expectancy and one of the main causes of death is cardiovascular disease (CVD). Modifiable risk factors for CVD include diabetes mellitus (DM) and dyslipidaemia. This study aimed to establish: (a) the prevalence and correlates of DM and dyslipidaemia; (b) the proportion of those whose condition was well controlled; and (c) the incidence of undiagnosed DM and dyslipidaemia in a long-stay inpatient schizophrenia population. METHODS: Data was collected to assess the physical health status of 110 inpatients with schizophrenia who had been in hospital for over one year...
February 12, 2018: Singapore Medical Journal
https://www.readbyqxmd.com/read/29430575/knowledge-and-attitude-of-singapore-schoolchildren-learning-cardiopulmonary-resuscitation-and-automated-external-defibrillator-skills
#3
Phek Hui Jade Kua, Alexander E White, Wai Yee Ng, Stephanie Fook-Chong, Eileen Kai Xin Ng, Yih Yng Ng, Marcus Eng Hock Ong
INTRODUCTION: Victims of out-of-hospital cardiac arrests require timely cardiopulmonary resuscitation (CPR) and early defibrillation. Persons making the call to emergency medical services will be asked to provide dispatcher-guided response until an ambulance arrives. Knowing what to expect in such circumstances should reduce both delay and confusion. METHODS: We conducted this study among schoolchildren aged 11-17 years using ten-item pre- and post-training surveys...
February 12, 2018: Singapore Medical Journal
https://www.readbyqxmd.com/read/29430574/how-the-personalities-of-medical-students-at-the-national-university-of-singapore-differ-from-the-local-non-medical-undergraduate-population-a-cross-sectional-study
#4
Lyn Li Lean, Ryan Yee Shiun Hong, Lian Kah Ti
INTRODUCTION: Integrity and willingness to contribute to society are desired traits of medical students beyond academic excellence. We investigated the personality traits of medical students at the National University of Singapore (NUS), Singapore, as they were about to become doctors. Personality traits were compared with a peer population of local university students. METHODS: This study was conducted between October 2013 and December 2014. Year 4 medical students were administered the Revised NEO (Neuroticism-Extraversion-Openness) Personality Inventory (NEO PI-R), a 240-item Likert scale personality test...
February 12, 2018: Singapore Medical Journal
https://www.readbyqxmd.com/read/29372261/patients-with-primary-restless-legs-syndrome-have-higher-prevalence-of-autonomic-dysfunction-and-irritable-bowel-syndrome
#5
Bilgehan Atılgan Acar, Mustafa Atahan Gürkan Acar, Türkan Acar, Ceyhun Varım, Aybala Neslihan Alagöz, Enis Bekir Demiryürek, Belma Doğan Güngen, Yeşim Güzey Aras
INTRODUCTION: Given the limited data on autonomic dysfunction in patients with primary restless legs syndrome (pRLS), we compared the autonomic dysfunction and presence of irritable bowel syndrome (IBS) among patients with pRLS with those among control patients. METHODS: Consecutive adult drug-naïve patients with pRLS, and age- and gender-matched healthy control patients were enrolled in this study. Diagnoses, based on validated self-reported questionnaires, were made using the following guidelines: the Rome III Classification System for Functional Gastrointestinal Disorders for IBS; the Beck Anxiety Inventory (BAI) and Beck Depression Inventory (BDI) for the presence of anxiety and depression, respectively; the Pittsburgh Sleep Quality Index (PSQI) for severity of sleep disturbances; and Scales for Outcomes in Parkinson's disease-Autonomic (SCOPA-AUT) for autonomic dysfunction...
January 26, 2018: Singapore Medical Journal
https://www.readbyqxmd.com/read/29372260/comparison-of-the-outcome-measures-from-different-pathways-post-total-knee-arthroplasty
#6
Hiok Yang Chan, Rehena Sultana, Seng Jin Yeo, Shi-Lu Chia, Hee Nee Pang, Ngai Nung Lo
INTRODUCTION: The benefits of extended inpatient rehabilitation post-total knee arthroplasty (TKA) in local community hospitals (CHs) are unproven. Our study compared functional outcomes between patients discharged home and to CHs post TKA. METHODS: A case-control study was conducted of patients undergoing primary unilateral TKA. Consecutive patients (n = 1,065) were retrospectively reviewed using Knee Society Clinical Rating Score (KSCRS), 36-item Short Form Health Survey (SF-36) and Oxford Knee Score (OKS) preoperatively, six-month and two-year follow-ups...
January 26, 2018: Singapore Medical Journal
https://www.readbyqxmd.com/read/29297090/outcome-and-risk-factors-of-patients-with-acute-fatty-liver-of-pregnancy-a-multicentre-retrospective-study
#7
Qiang Gao, Xin Qu, Xiukai Chen, Jicheng Zhang, Fen Liu, Suochen Tian, Chunting Wang
INTRODUCTION: Acute fatty liver of pregnancy (AFLP) frequently causes liver failure in pregnant women. The relatively high mortality of AFLP behoves a better understanding of its clinical characteristics, management, outcomes and risk factors. We aimed to describe the characteristics of AFLP, and further assess its outcomes and potential risk factors from the perspectives of the mother and fetus. METHODS: This was a retrospective cohort study of 133 patients with AFLP hospitalised at four tertiary hospitals in China between January 2009 and April 2014...
January 3, 2018: Singapore Medical Journal
https://www.readbyqxmd.com/read/29297089/cricoid-ridge-ossification-mimicking-ingested-fish-bone-on-plain-radiography-prevalence-in-singapore
#8
Sheldon Jin Keat Ng, Joseph King Tak Lee, Yee Liang Thian
INTRODUCTION: Ossification of the cricoid ridge mimicking impacted upper aerodigestive tract fish bone has been described in several case reports. We performed this study to determine the prevalence of such ossification in an adult population from Singapore and to identify specific imaging features that may be used as aid in differentiating patients with cricoid ridge ossification from those having an upper aerodigestive tract impacted fish bone. METHODS: We retrospectively evaluated 442 lateral neck radiographs of patients aged 16 years and above that were performed in the adult emergency department at the National University Hospital, Singapore, during the four-month period between 1 September 2014 and 31 December 2014...
January 3, 2018: Singapore Medical Journal
https://www.readbyqxmd.com/read/29297088/changes-in-operative-experience-after-the-introduction-of-residency-an-objective-comparison-of-surgical-and-endoscopic-volumes
#9
Kherru Sarah Sim, Jin Yao Teo, Peng Chung Cheow
INTRODUCTION: The SingHealth Residency General Surgery Programme replaced the basic and advanced specialist training (AST) system in Singapore in 2010. The relative merits of both systems continue to be debated, especially concerning the operational readiness of graduating residents. We set out to compare the operative and endoscopic volumes of graduates from the AST system with those from the first graduating batch of the residency programme during their registrar (or equivalent) years, as a reflection of procedural experience gained during traineeship...
January 3, 2018: Singapore Medical Journal
https://www.readbyqxmd.com/read/29297087/biobrane-dressing-for-paediatric-burns-in-singapore-a-retrospective-review
#10
Cong Fan, Chong Han Pek, Yong Chen Por, Gale Jue Shuang Lim
INTRODUCTION: The ideal burn dressing for children should aim to alleviate pain, decrease length of hospital stay and minimise complications, such as conversion and infection. The current literature is still inconclusive with regard to the gold standard burn dressing for the paediatric population. METHODS: We retrospectively reviewed children with superficial partial thickness burns admitted to our paediatric burn unit from January 2014 to April 2015. A total of 30 patients were included in our study, of which 13 had Biobrane dressing...
January 3, 2018: Singapore Medical Journal
https://www.readbyqxmd.com/read/29214323/economic-value-of-using-partially-hydrolysed-infant-formula-for-risk-reduction-of-atopic-dermatitis-in-high-risk-infants-not-exclusively-breastfed-in-singapore
#11
Marc F Botteman, Abhijeet J Bhanegaonkar, Erica G Horodniceanu, Xiang Ji, Bee Wah Lee, Lynette P Shek, Hugo Ps Van Bever, Patrick Detzel
INTRODUCTION: Previous trials have demonstrated reductions in atopic dermatitis (AD) incidence when healthy, high-risk, non-exclusively breastfed infants were fed until four months of age with 100% whey-based partially hydrolysed formula (PHF-W) versus standard cow's milk formula (CMF). We assessed this intervention's cost-effectiveness in Singapore. METHODS: Modelling techniques were used to simulate, from birth to Month 30, the incidence, and clinical and economic burden of AD in high-risk, non-exclusively breastfed infants fed with PHF-W or CMF for up to four months...
December 7, 2017: Singapore Medical Journal
https://www.readbyqxmd.com/read/29214322/road-traffic-accidents-in-children-the-what-how-and-why
#12
Yue Yen Lee, Eric Fang, Yanyi Weng, Sashikumar Ganapathy
INTRODUCTION: Road traffic accidents (RTAs) in Singapore involving children were evaluated, with particular focus on the epidemiology, surrounding circumstances and outcomes of these accidents. Key factors associated with worse prognosis were identified. We proposed some measures that may be implemented to reduce the frequency and severity of such accidents. METHODS: This was a retrospective study of RTAs involving children aged 0-16 years who presented to the Children's Emergency at KK Women's and Children's Hospital, Singapore, from January 2011 to June 2014...
December 7, 2017: Singapore Medical Journal
https://www.readbyqxmd.com/read/29214321/hemithyroidectomy-for-low-risk-follicular-carcinoma-of-thyroid-results-from-a-regional-hospital
#13
Tam-Lin Chow, Susanna Wai-Yin Tam, Chi-Yee Choi, Wilson Wai-Yin Kwan
INTRODUCTION: Excellent outcome after conservative thyroid surgery for low-risk follicular thyroid carcinoma (FTC) has been reported from highly specialised centres. However, it is uncertain whether similar treatment results can be achieved in low-volume hospitals. METHODS: At our institution, 49 patients with FTC were treated during 1991-2014. Patients with minimally invasive FTC (MIFTC) were usually treated with hemithyroidectomy. The demographic data, pathology, treatment modality and oncological outcomes of these patients were retrospectively evaluated...
December 7, 2017: Singapore Medical Journal
https://www.readbyqxmd.com/read/29376190/a-time-for-reflection-and-thanks
#14
Kian Keong Poh
No abstract text is available yet for this article.
January 2018: Singapore Medical Journal
https://www.readbyqxmd.com/read/29376189/clinics-in-diagnostic-imaging-183
#15
Qi Hui Bernice Heng, Dinesh Chinchure, Reyaz Moiz Singaporewalla
Hydrocoele of the canal of Nuck is a rare condition in adult women caused by a failure of complete obliteration of the canal of Nuck. It may be likened to a patent processus vaginalis in men. In most cases, the diagnosis is made during surgery as it is often mistaken for an inguinal hernia. We report a case where the diagnosis of this condition was made preoperatively on imaging. The salient anatomy, clinical features, radiological images and surgical management are discussed and the medical literature reviewed...
January 2018: Singapore Medical Journal
https://www.readbyqxmd.com/read/29376188/fall-concern-about-older-persons-shifts-to-carers-as-changing-health-policy-focuses-on-family-home-based-care
#16
Seng Giap Marcus Ang, Anthony Paul O'Brien, Amanda Wilson
With the Singaporean population ageing at an exponential rate, home carers are increasingly becoming essential partners in fall prevention and care delivery for older persons living at home and in the community. Singapore, like other Asian countries, regards the family as the main support structure for the older person, and national policies have been implemented to support this cultural expectation. Family carers experience similar concerns as older persons with regard to fall risk, and identifying and addressing these concerns can potentially lower fall risk and improve fall prevention for older persons...
January 2018: Singapore Medical Journal
https://www.readbyqxmd.com/read/29376187/severo-ochoa-1905-1993-the-man-behind-rna
#17
Siang Yong Tan, Kate Pettigrew
No abstract text is available yet for this article.
January 2018: Singapore Medical Journal
https://www.readbyqxmd.com/read/29376186/ministry-of-health-clinical-practice-guidelines-hypertension
#18
Jam Chin Tay, Ashish Anil Sule, E K Chew, Jeannie S Tey, Titus Lau, Simon Lee, Sze Haur Lee, Choon Kit Leong, Soo Teik Lim, Lip Ping Low, Vernon Min Sen Oh, K Y Phoon, Kian Wee Kenneth Tan, Akira Wu, Loo See Yeo
The Ministry of Health (MOH) has updated the clinical practice guidelines on hypertension to provide doctors and patients in Singapore with evidence-based treatment for hypertension. This article reproduces the introduction and executive summary (with recommendations from the guidelines) from the MOH clinical practice guidelines on hypertension, for the information of SMJ readers. Chapters and page numbers mentioned in the reproduced extract refer to the full text of the guidelines, which are available from the Ministry of Health website: http://www...
January 2018: Singapore Medical Journal
https://www.readbyqxmd.com/read/29376185/internationalising-singapore-medicine
#19
Choon Yong Loo
No abstract text is available yet for this article.
January 2018: Singapore Medical Journal
https://www.readbyqxmd.com/read/29376184/authors-reply
#20
Hui Bin Yvonne Chan, Choon How How, Chung Wai Mark Ng
No abstract text is available yet for this article.
January 2018: Singapore Medical Journal
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