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Singapore Medical Journal

Huay Cheem Tan, Rajiv Ananthakrishna
The evolution of coronary metal stents has been well known for the past three decades, but it is only in the recent past that research on bioresorbable scaffolds has gained momentum in the field of percutaneous coronary intervention. Although second-generation drug-eluting metal stents are the gold standard for the treatment of obstructive coronary artery disease, a few drawbacks exist. The development of bioresorbable scaffolds is an attempt to overcome the limitations of metal stents. This review highlights the rationale for a bioresorbable scaffold, its properties and its potential application...
November 21, 2016: Singapore Medical Journal
Bryan Wei Hoe Tam, Dana Rui Ting Lo, Daniel Wen Hao Seah, Jun Xian Lee, Zann Fang Ying Foo, Zoe Yu Yah Poh, Fionna Xiu Jun Thong, Sam Kim Yang Sim, Chew Sim Chee
There is relatively less research available on the effect of mindfulness on cognitive functioning. However, it has recently gained more attention due to the ageing population, as catalysed by recent findings on brain function and cellular ageing. Recognising the potential benefits of practicing mindfulness, we aimed to develop a localised, self-training mindfulness programme, guided by expert practitioners and usability testing, for older Singaporean adults. This was followed by a pilot study to examine the effects of this self-training programme on the cognitive functioning in older adults in Singapore...
November 21, 2016: Singapore Medical Journal
Hui Min Lim, Lee Gan Goh, T Thirumoorthy
Medical reports are required to support court applications to appoint a deputy to make decisions on behalf of a person who has lost mental capacity. The doctor writing such a medical report needs to be able to systematically assess the mental capacity of the person in question, in order to gather the necessary evidence for the Court to make a decision. If the medical report is not adequate, the application will be rejected and the appointment of the deputy delayed. This article sets out the best practices for performing the assessment, and the common errors, issues of concern and best practices in writing the medical report...
October 18, 2016: Singapore Medical Journal
Christina Jiun-Yu Tan, Grant E Sklar
INTRODUCTION: Paracetamol is the most common pharmaceutical agent implicated in toxic exposure in Singapore. This study aimed to describe the characteristics of paracetamol overdose in the adult population managed at a tertiary healthcare facility in Singapore. METHODS: Medical records of adult patients hospitalised with a diagnosis of paracetamol overdose at National University Hospital, Singapore, over a three-year period from January 2011 to December 2013 were retrospectively reviewed...
October 18, 2016: Singapore Medical Journal
Ira Sun, Jia Xu Lim, Chun Peng Goh, Shiong Wen Low, Ramez W Kirollos, Chuen Seng Tan, Sein Lwin, Tseng Tsai Yeo
INTRODUCTION: Postoperative cerebrospinal fluid (CSF) leak is a serious complication following trans-sphenoidal surgery for which elevated body mass index (BMI) has been implicated as a risk factor, albeit only in two recent North American studies. Given the paucity of evidence, we sought to determine if this association held true in an Asian population, where BMI criteria for obesity differ from the international standard. METHODS: A retrospective study of 119 patients who underwent 123 trans-sphenoidal procedures for sellar lesions between May 2000 and May 2012 was conducted...
September 22, 2016: Singapore Medical Journal
Wann Jia Loh, Yue Yu, Chian Min Loo, Su Ying Low
INTRODUCTION: The aim of this study was to identify patient characteristics and risk factors associated with in-hospital mortality of patients with pulmonary tuberculosis (PTB) requiring intensive care unit (ICU) management. METHODS: A retrospective chart review was conducted of all patients with active PTB admitted to the ICU at Singapore General Hospital, Singapore, between January 2005 and December 2010. RESULTS: There were 2,155 patients with active PTB diagnosed, of whom 83 (3...
September 22, 2016: Singapore Medical Journal
Tamra Lysaght, Tsung-Ling Lee, Sangeetha Watson, Zohar Lederman, Michele Bailey, Paul Anantharajah Tambyah
No abstract text is available yet for this article.
September 19, 2016: Singapore Medical Journal
Sanjay de Mel, Yunxin Chen, Sathish Kumar Gopalakrishnan, Melissa Ooi, Constance Teo, Daryl Tan, Min Li Claire Teo, Allison Cy Tso, Lian King Lee, Chandramouli Nagarajan, Yeow Tee Goh, Wee Joo Chng
Multiple myeloma (MM) is an incurable plasma cell neoplasm with an incidence of 100 patients per year in Singapore. Major advances have been made in the diagnosis, risk stratification and treatment of MM in the recent past. The reclassification of a subset of patients with smouldering MM, based on high-risk biomarkers, and the development of the revised international staging system are among the key new developments in diagnosis and staging. The use of novel agent-based treatment has resulted in significant improvements in the survival and quality of life of many patients with MM...
September 9, 2016: Singapore Medical Journal
Hui Jin Toh, Zhen Yu Lim, Philip Yap, Terence Tang
INTRODUCTION: Prolonged stay in acute hospitals increases the risks of hospital-acquired infections in older patients, and disrupts patient flow and access to care due to bed shortages. Therefore, factors associated with prolonged length of stay (pLOS) among older patients (aged over 78 years) in a tertiary hospital were investigated to identify potentially modifiable risk factors that could help direct interventions to reduce pLOS. METHODS: During a three-month period from January 2013 to March 2013, 72 patients with pLOS (length of stay [LOS] ≥ 21 days) were identified and compared to 281 randomly selected control patients (LOS < 21 days) for demographic and clinical variables using univariate and multivariate logistic regression analyses...
September 9, 2016: Singapore Medical Journal
Alice Kurien, Sarita Narang, How Chuan Han
INTRODUCTION: We aimed to study the efficacy and safety of the tension-free vaginal tape (TVT)-Abbrevo procedure for female stress urinary incontinence (SUI). METHODS: This was a prospective cohort study that aimed to determine the subjective and objective cure, improvement of SUI and incidence of complications among women who underwent TVT-Abbrevo for SUI during a period of 22 months from September 2011 to June 2013. RESULTS: A total of 76 patients, with a mean age of 48...
September 9, 2016: Singapore Medical Journal
(no author information available yet)
No abstract text is available yet for this article.
November 2016: Singapore Medical Journal
Chaozer Er, Ashish Anil Sule
No abstract text is available yet for this article.
November 2016: Singapore Medical Journal
Tommy Koh
No abstract text is available yet for this article.
November 2016: Singapore Medical Journal
Rositaa Ibrahim, Kartini Rahmat, Farhana Fadzli, Faizatul Izza Rozalli, Caroline Judy Westerhout, Kasumawati Alli, Anushya Vijayananthan, Fatimah Moosa
INTRODUCTION: This study aimed to evaluate the vascular pattern of solid breast lesions using power Doppler ultrasonography (PDUS) and assess whether the presence of intratumoural penetrating vessels can predict breast cancer malignancy. METHODS: Greyscale ultrasonography (US) and PDUS were prospectively performed on 91 women in Malaysia with histopathologically proven breast lesions. The diagnostic accuracy of greyscale US, PDUS, and both greyscale US and PDUS was calculated and compared...
November 2016: Singapore Medical Journal
Chung Wai Mark Ng, Choon How How, Yin Ping Ng
Major depression is a common condition seen in the primary care setting, often presenting with somatic symptoms. It is potentially a chronic illness with considerable morbidity, and a high rate of relapse and recurrence. Major depression has a bidirectional relationship with chronic diseases, and a strong association with increased age and coexisting mental illnesses (e.g. anxiety disorders). Screening can be performed using clinical tools for major depression, such as the Patient Health Questionaire-2, Patient Health Questionaire-9 and Beck Depression Inventory, so that timely treatment can be initiated...
November 2016: Singapore Medical Journal
Su Kai Gideon Ooi, Tien Jin Tan, James Chi Yong Ngu
A 46-year-old Chinese woman with a history of cholecystectomy and appendicectomy presented to the emergency department with symptoms of intestinal obstruction. Physical examination revealed central abdominal tenderness but no clinical features of peritonism. Plain radiography of the abdomen revealed a grossly distended large bowel loop with the long axis extending from the right lower abdomen toward the epigastrium, and an intraluminal air-fluid level. These findings were suspicious for an acute caecal volvulus, which was confirmed on subsequent contrast-enhanced computed tomography (CT) of the abdomen and pelvis...
November 2016: Singapore Medical Journal
Ee Heok Kua, Jade Phek Hui Kua
The Singapore Medical Journal (SMJ) has in the past 55 years reflected the phenomenal socioeconomic progress of Singapore. Publications in the pre-independent years were mainly on diseases like cholera, diphtheria, leprosy, tetanus and worm infestation. In the new millennium, the research papers included molecular genetics, health economics, obesity, Internet medicine, cancer, cosmetic surgery and palliative medicine. The annual SMA Lecture published in the SMJ provides an ethical compass for doctors to remind them of primum non nocere...
November 2016: Singapore Medical Journal
Jia Loon Chong
Kidney transplantation is the preferred treatment for eligible end-stage renal disease patients. However, the supply of donated kidneys has been consistently insufficient to meet the transplantation requirements of the population. In this paper, I discuss the feasibility of several policy options that engage potential donors or key individuals in a Singapore context, including financial and non-financial incentives for deceased/living organ donors and their families, improving actualisation rates of both donation after brain death, donation after cardiac death through quality improvement programmes and remuneration schemes, and a media platform for directed organ donation...
October 2016: Singapore Medical Journal
Beuy Joob, Viroj Wiwanitkit
No abstract text is available yet for this article.
October 2016: Singapore Medical Journal
Jung Ii Lee, Duk Hee Lee
No abstract text is available yet for this article.
October 2016: Singapore Medical Journal
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