Johann Sigurjonsson, David Grubb, Anders Grubb, Anders Christensson, Carl M Öberg, Per Ederoth, Sasha Koul, Matthias Götberg, Troels Yndigegn, Tim Tödt, Benedicte Viterius, Henrik Bjursten
The recently discovered selective glomerular hypofiltration syndromes have increased interest in the actual elimination of molecules in the human kidney. In the present study, a novel human model was introduced to directly measure the single-pass renal elimination of molecules of increasing size. Plasma concentrations of urea, creatinine, C-peptide, insulin, pro-BNP, β2 -microglobulin, cystatin C, troponin-T, orosomucoid, albumin, and IgG were analysed in arterial and renal venous blood from 45 patients undergoing Transcatheter Aortic Valve Implantation (TAVI)...
April 8, 2024: Scandinavian Journal of Clinical and Laboratory Investigation