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Journal of Nutrition

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https://www.readbyqxmd.com/read/28701389/meal-frequency-and-timing-are-associated-with-changes-in-body-mass-index-in-adventist-health-study-2
#1
Hana Kahleova, Jan Irene Lloren, Andrew Mashchak, Martin Hill, Gary E Fraser
Background: Scientific evidence for the optimal number, timing, and size of meals is lacking.Objective: We investigated the relation between meal frequency and timing and changes in body mass index (BMI) in the Adventist Health Study 2 (AHS-2), a relatively healthy North American cohort.Methods: The analysis used data from 50,660 adult members aged ≥30 y of Seventh-day Adventist churches in the United States and Canada (mean ± SD follow-up: 7.42 ± 1.23 y). The number of meals per day, length of overnight fast, consumption of breakfast, and timing of the largest meal were exposure variables...
July 12, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28701388/should-we-restrict-vitamin-a-intake-a-minor-contributor-to-plasma-retinol-turnover-when-using-retinol-isotope-dilution-equations-to-estimate-an-individual-s-vitamin-a-status-or-should-vitamin-a-balance-be-maintained
#2
Jennifer Lynn Ford, Joanne Balmer Green, Michael H Green
We discuss whether dietary vitamin A intake should be restricted or maintained at balance when retinol isotope dilution equations are applied to estimate an individual's vitamin A total body stores (TBS) after oral administration of a labeled dose of vitamin A. Although, at first glance, restriction makes sense as a way to prevent dilution of tracer in plasma, further investigation of the assumptions underlying the widely used isotope dilution equation presented by Olson's laboratory in 1989, as well as the compartmental modeling results presented in this article, indicate that, in fact, restriction leads to an incorrect prediction of TBS if steady state retinol isotope dilution equations are applied at the traditional time (21 d)...
July 12, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28701387/high-iron-stores-in-the-low-malaria-season-increase-malaria-risk-in-the-high-transmission-season-in-a-prospective-cohort-of-rural-zambian-children
#3
Maxwell A Barffour, Kerry J Schulze, Christian L Coles, Justin Chileshe, Ng'andwe Kalungwana, Margia Arguello, Ward Siamusantu, William J Moss, Keith P West, Amanda C Palmer
Background: Higher iron stores, defined by serum ferritin (SF) concentration, may increase malaria risk.Objective: We evaluated the association between SF assessed during low malaria season and the risk of malaria during high malaria season, controlling for inflammation.Methods: Data for this prospective study were collected from children aged 4-8 y (n = 745) participating in a biofortified maize efficacy trial in rural Zambia. All malaria cases were treated at baseline (September 2012). We used baseline SF and malaria status indicated by positive microscopy at endline (March 2013) to define exposure and outcome, respectively...
July 12, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28701386/low-calcium-intake-in-midpregnancy-is-associated-with-hypertension-development-within-10-years-after-pregnancy-the-norwegian-mother-and-child-cohort-study
#4
Grace M Egeland, Svetlana Skurtveit, Solveig Sakshaug, Anne Kjersti Daltveit, Bjørn E Vikse, Margaretha Haugen
Background: Low dietary calcium intake may be a risk factor for hypertension, but studies conflict.Objective: We evaluated the ability to predict hypertension within 10 y after delivery based on calcium intake during midpregnancy.Methods: The Norwegian Mother and Child Cohort Study of women delivering in 2004-2009 was linked to the Norwegian Prescription Database (2004-2013) to ascertain antihypertensive medication usage >90 d after delivery. Women with hypertension before pregnancy were excluded, leaving 60,027 mothers for analyses...
July 12, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28701385/biotin-from-nutrition-to-therapeutics
#5
REVIEW
Donald M Mock
Although frank symptomatic biotin deficiency is rare, some evidence suggests that marginal biotin deficiency occurs spontaneously in a substantial proportion of women during normal human pregnancy and might confer an increased risk of birth defects. Herein I review 1) advances in assessing biotin status, including the relation between acylcarnitine excretion and biotin status; 2) recent studies of biotin status in pregnancy; 3) advances in understanding the role of biotin in gene expression and the potential roles of biotinylated proteins that are neither histones nor carboxylases; and 4) novel large-dose biotin supplementation as therapy for multiple sclerosis...
July 12, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28679627/ablation-of-arginase-ii-spares-arginine-and-abolishes-the-arginine-requirement-for-growth-in-male-mice
#6
Inka C Didelija, Mahmoud A Mohammad, Juan C Marini
Background: Arginine is considered a semiessential amino acid in many species, including humans, because under certain conditions its demand exceeds endogenous production. Arginine availability, however, is determined not only by its production but also by its disposal. Manipulation of disposal pathways has the potential to increase availability and thus abolish the requirement for arginine.Objective: The objective of the study was to test the hypothesis that arginase II ablation increases arginine availability for growth...
July 5, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28659408/the-nitrogen-moieties-of-dietary-nonessential-amino-acids-are-distinctively-metabolized-in-the-gut-and-distributed-to-the-circulation-in-rats
#7
Hidehiro Nakamura, Yasuko Kawamata, Tomomi Kuwahara, Ryosei Sakai
Background: Although previous growth studies in rodents have indicated the importance of dietary nonessential amino acids (NEAAs) as nitrogen sources, individual NEAAs have different growth-promoting activities. This phenomenon might be attributable to differences in the nitrogen metabolism of individual NEAAs. Objective: The aim of this study was to compare nitrogen metabolism across dietary NEAAs with the use of their (15)N isotopologues.Methods: Male Fischer rats (8 wk old) were given 1.0 g amino acid-defined diets containing either (15)N-labeled glutamate, glutamine (amino or amide), aspartate, alanine, proline, glycine, or serine hourly for 5-6 h...
June 28, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28659407/an-empirical-dietary-inflammatory-pattern-score-enhances-prediction-of-circulating-inflammatory-biomarkers-in-adults
#8
Fred K Tabung, Stephanie A Smith-Warner, Jorge E Chavarro, Teresa T Fung, Frank B Hu, Walter C Willett, Edward L Giovannucci
Background: Two indexes exist to describe dietary inflammatory potential: an empirical dietary inflammatory pattern (EDIP) composed of food groups as reported on a food-frequency questionnaire (FFQ) and a literature-derived dietary inflammatory index (DII) composed mainly of nutrients.Objective: We compared the ability of the 2 indexes to predict concentrations of inflammatory markers and hypothesized that the EDIP would be more predictive because it was derived on the basis of circulating inflammatory markers...
June 28, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28659406/early-postnatal-diets-affect-the-bioregional-small-intestine-microbiome-and-ileal-metabolome-in-neonatal-pigs
#9
Brian D Piccolo, Kelly E Mercer, Sudeepa Bhattacharya, Anne K Bowlin, Manish K Saraf, Lindsay Pack, Sree V Chintapalli, Kartik Shankar, Sean H Adams, Thomas M Badger, Laxmi Yeruva
Background: Breastfeeding is known to be protective against gastrointestinal disorders and may modify gut development. Although the gut microbiome has been implicated, little is known about how early diet affects the small intestine microbiome.Objective: We hypothesized that disparate early diets would promote unique microbial profiles in the small intestines of neonatal pigs.Methods: Male and female 2-d-old White Dutch Landrace pigs were either sow fed or provided dairy (Similac Advance powder; Ross Products Abbott Laboratories) or soy (Enfamil Prosobee Lipil powder; Mead Johnson Nutritionals) infant formulas until day 21...
June 28, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28659405/fish-oil-contaminated-with-persistent-organic-pollutants-induces-colonic-aberrant-crypt-foci-formation-and-reduces-antioxidant-enzyme-gene-expression-in-rats
#10
Mee Young Hong, Eunha Hoh, Brian Kang, Rebecca DeHamer, Jin Young Kim, Jan Lumibao
Background: Epidemiologic, clinical, and experimental studies have suggested that fish oil (FO), a rich source of n-3 (ω-3) polyunsaturated fatty acids, protects against colon cancer. However, this message is confounded by the FDA's warning that the consumption of certain types of fish should be restricted because of contamination with persistent organic pollutants (POPs), such as polychlorinated biphenyls (PCBs) and organochlorine pesticides.Objective: We examined FO contaminated with POPs (PCBs, dichlorodiphenyltrichloroethane, and chlordane) compared with unmodified FO on the risk factors of colon cancer development...
June 28, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28637686/high-serum-phospholipid-dihomo-%C3%AE-linoleic-acid-concentration-and-low-%C3%AE-5-desaturase-activity-are-associated-with-increased-risk-of-type-2-diabetes-among-japanese-adults-in-the-hitachi-health-study
#11
Shamima Akter, Kayo Kurotani, Masao Sato, Takuya Hayashi, Keisuke Kuwahara, Yumi Matsushita, Tohru Nakagawa, Maki Konishi, Toru Honda, Shuichiro Yamamoto, Takeshi Hayashi, Mitsuhiko Noda, Tetsuya Mizoue
Background: The association between the circulating fatty acid (FA) composition and type 2 diabetes (T2D) has been reported in Western populations, but evidence is scarce among Asian populations, including Japanese, who consume large amounts of fish.Objective: The objective of the present study was to prospectively examine the association between circulating concentrations of individual FAs and T2D incidence among Japanese adults.Methods: We conducted a nested case-control study in a cohort of 4754 employees, aged 34-69 y, who attended a comprehensive health checkup in 2008-2009 and donated blood samples for the Hitachi Health Study...
June 21, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28637685/milk-oligosaccharides-inhibit-human-rotavirus-infectivity-in-ma104-cells
#12
Daniel R Laucirica, Vassilis Triantis, Ruud Schoemaker, Mary K Estes, Sasirekha Ramani
Background: Oligosaccharides in milk act as soluble decoy receptors and prevent pathogen adhesion to the infant gut. Milk oligosaccharides reduce infectivity of a porcine rotavirus strain; however, the effects on human rotaviruses are less well understood.Objective: In this study, we determined the effect of specific and abundant milk oligosaccharides on the infectivity of 2 globally dominant human rotavirus strains.Methods: Four milk oligosaccharides-2'-fucosyllactose (2'FL), 3'-sialyllactose (3'SL), 6'-sialyllactose (6'SL), and galacto-oligosaccharides-were tested for their effects on the infectivity of human rotaviruses G1P[8] and G2P[4] through fluorescent focus assays on African green monkey kidney epithelial cells (MA104 cells)...
June 21, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28615383/introduction-to-the-fourth-global-summit-on-the-health-effects-of-yogurt
#13
REVIEW
Sharon M Donovan, Jordi Salas-Salvadó
No abstract text is available yet for this article.
June 14, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28615380/leucine-differentially-regulates-gene-specific-translation-in-mouse-skeletal-muscle
#14
Micah J Drummond, Paul T Reidy, Lisa M Baird, Brian K Dalley, Michael T Howard
Background: Amino acids, especially leucine, are particularly effective in promoting protein synthesis. Leucine is known to increase the rate of protein synthesis in skeletal muscle through the mechanistic target of rapamycin complex 1-dependent, as well as -independent, signaling pathways. However, the overall translation program is poorly defined, and it is unknown how the activation of these pathways differentially controls the translation of specific mRNAs.Objective: Ribosome profiling and RNA sequencing were used to precisely define the translational program activated by an acute oral dose of leucine...
June 14, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28615379/daily-consumption-of-lipid-based-nutrient-supplements-containing-250-%C3%AE-g-iodine-does-not-increase-urinary-iodine-concentrations-in-pregnant-and-postpartum-women-in-bangladesh
#15
Malay K Mridha, Susana L Matias, Rina Rani Paul, Sohrab Hussain, Md Showkat Ali Khan, Zakia Siddiqui, Barkat Ullah, Mostofa Sarker, Mokbul Hossain, Rebecca T Young, Charles D Arnold, Kathryn G Dewey
Background: Maternal iodine deficiency during pregnancy and lactation is common in Bangladesh.Objective: We evaluated the effect of lipid-based nutrient supplements for pregnant and lactating women (LNS-PL) on urinary iodine concentration (UIC).Methods: We conducted a cluster-randomized controlled effectiveness trial in which we enrolled 4011 pregnant women at ≤20 gestational weeks. Women in 48 clusters received iron and folic acid (IFA; 60 mg Fe/d + 400 μg folic acid/d) and women in 16 clusters received LNS-PL (20 g/d, 118 kcal) containing 22 vitamins and minerals (including 250 μg I)...
June 14, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28615378/amino-acid-absorption-in-the-large-intestine-of-humans-and-porcine-models
#16
REVIEW
Nikkie van der Wielen, Paul J Moughan, Marco Mensink
Dietary protein quality has been recognized as a critical issue by international authorities because it can affect important functions of the body. To predict protein quality, the FAO introduced the Digestible Indispensable Amino Acid Score. This score depends on ileal amino acid (AA) digestibility; therefore, the assumption is made that AAs are not absorbed in nutritionally relevant amounts from the large intestine. This article reviews the evidence for this assumption by considering the role of the mammalian large intestine in dietary protein and AA digestion and absorption, with particular reference to adult humans...
June 14, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28615377/after-mexico-implemented-a-tax-purchases-of-sugar-sweetened-beverages-decreased-and-of-water-increased-difference-by-place-of-residence-household-composition-and-income-level
#17
M Arantxa Colchero, Mariana Molina, Carlos M Guerrero-López
Background: In January 2014, Mexico implemented a tax on sugar-sweetened beverage (SSB) purchases of 1 peso/L.Objective: We examined the heterogeneity of changes in nonalcoholic beverage (SSB and bottled water) purchases after the tax was implemented by household income, urban and rural strata, and household composition.Methods: We used 4 rounds of the National Income and Expenditure Surveys: 2008, 2010, 2012, and 2014. Changes in purchases in per capita liters per week were estimated with the use of 2-part models to adjust for nonpurchases...
June 14, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28615376/smell-and-taste-dysfunction-is-associated-with-higher-serum-total-cholesterol-concentrations-in-chinese-adults
#18
Zhe Huang, Shue Huang, Hongliang Cong, Zheng Li, Junjuan Li, Kathleen L Keller, Gregory C Shearer, Penny M Kris-Etherton, Shouling Wu, Xiang Gao
Background: Several lipid-related hormones and peptides, such as glucagon-like peptide-1 and leptin, are involved in the regulation of taste and smell function. However, to our knowledge, it remains unknown whether these chemosensory functions are associated with lipid profiles.Objective: We examined the cross-sectional association between taste and smell dysfunction and blood cholesterol concentrations.Methods: With the use of a questionnaire, we assessed chronic smell and taste dysfunction in 12,627 Chinese participants (10,418 men and 2209 women; mean age: 54...
June 14, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28615375/inclusion-of-almonds-in-a-cholesterol-lowering-diet-improves-plasma-hdl-subspecies-and-cholesterol-efflux-to-serum-in-normal-weight-individuals-with-elevated-ldl-cholesterol
#19
Claire E Berryman, Jennifer A Fleming, Penny M Kris-Etherton
Background: Almonds may increase circulating HDL cholesterol when substituted for a high-carbohydrate snack in an isocaloric diet, yet little is known about the effects on HDL biology and function.Objective: The objective was to determine whether incorporating 43 g almonds/d in a cholesterol-lowering diet would improve HDL subspecies and function, which were secondary study outcomes.Methods: In a randomized, 2-period, crossover, controlled-feeding study, a diet with 43 g almonds/d (percentage of total energy: 51% carbohydrate, 16% protein, and 32% total and 8% saturated fat) was compared with a similar diet with an isocaloric muffin substitution (58% carbohydrate, 15% protein, and 26% total and 8% saturated fat) in men and women with elevated LDL cholesterol...
June 14, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28615374/a-cross-sectional-survey-in-rural-bihar-india-indicates-that-nutritional-status-diet-and-stimulation-are-associated-with-motor-and-mental-development-in-young-children
#20
Leila M Larson, Melissa F Young, Usha Ramakrishnan, Amy Webb Girard, Pankaj Verma, Indrajit Chaudhuri, Sridhar Srikantiah, Reynaldo Martorell
Background: Many malnourished children in resource-poor settings fail to fulfill their developmental potential.Objectives: The objectives of this analysis were to examine the nutritional, psychosocial, environmental, and household correlates of child development in Bihar, India, and identify mediators between dietary diversity and mental development.Methods: Using 2-stage cluster randomized sampling, we surveyed 4360 households with children 6-18 mo of age in the West Champaran district of Bihar. We measured motor and mental development with the use of the Developmental Milestones Checklist II...
June 14, 2017: Journal of Nutrition
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