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Journal of Nutrition

Renjuan Chen, Qian Li, Wenli Cui, Xiaoyi Wang, Qin Gao, Chunrong Zhong, Guoqiang Sun, Xinlin Chen, Guoping Xiong, Xuefeng Yang, Liping Hao, Nianhong Yang
Background: Maternal iodine status has been suggested to affect birth outcomes. Few studies have focused on its effects on fetal growth during pregnancy. Objective: This study aimed to assess maternal iodine status during early pregnancy and further examine the relation between maternal iodine status and fetal growth. Methods: A total of 2087 singleton-pregnant women participating in the Tongji Maternal and Child Health Cohort study were involved...
September 18, 2018: Journal of Nutrition
Hee Young Yun, Johanna W Lampe, Lesley F Tinker, Marian L Neuhouser, Shirley A A Beresford, Kristine R Niles, Yasmin Mossavar-Rahmani, Linda G Snetselaar, Linda Van Horn, Ross L Prentice, Diane M O'Brien
Background: Natural abundance stable isotope ratios are candidate biomarkers of dietary intake that have not been evaluated in a controlled feeding study in a US population. Objectives: Our goals were to evaluate dietary associations with serum carbon (CIR), nitrogen (NIR), and sulfur (SIR) isotope ratios in postmenopausal women, and to evaluate whether statistical models of dietary intake that include multiple isotopes and participant characteristics meet criteria for biomarker evaluation...
September 17, 2018: Journal of Nutrition
Andrew D Jones, Hilary Creed-Kanashiro, Karl S Zimmerer, Stef de Haan, Miluska Carrasco, Krysty Meza, Gisella S Cruz-Garcia, Milka Tello, Franklin Plasencia Amaya, R Margot Marin, Lizette Ganoza
Background: The extent to and mechanisms by which agricultural biodiversity may influence diet diversity and quality among women are not well understood. Objectives: We aimed to 1) determine the association of farm-level agricultural biodiversity with diet diversity and quality among women of reproductive age in Peru and 2) determine the extent to which farm market orientation mediates or moderates this association. Methods: We surveyed 600 households with the use of stratified random sampling across 3 study landscapes in the Peruvian Andes with diverse agroecological and market conditions...
September 13, 2018: Journal of Nutrition
Kevin C Maki, Wendy Hasse, Mary R Dicklin, Marjorie Bell, Mary A Buggia, Martha E Cassens, Fulya Eren
Background: Few trials have examined the effects of coconut oil consumption in comparison with polyunsaturated fatty acid-rich oils such as corn oil. Objective: This trial assessed the effects of consuming foods made with corn oil compared with coconut oil on lipids, glucose homeostasis, and inflammation. Methods: This was a preliminary randomized crossover study of men (n = 12) and women (n = 13) with a mean age of 45.2 y, mean body mass index (in kg/m2) of 27...
September 10, 2018: Journal of Nutrition
Aya Masuda, Jos G M Houdijk, Judith E Allen, Spiridoula Athanasiadou
Background: It has been shown that dietary protein supplementation during lactation boosts immunity in Nippostrongylus brasiliensis-infected periparturient rats. It is not known whether body protein reserves accumulated during gestation have a similar effect during lactation. Objective: This study aimed to quantify the impact of body protein reserves and dietary protein supplementation on maternal performance and immune responses to N. brasiliensis during lactation...
September 10, 2018: Journal of Nutrition
Aulo Gelli, Amy Margolies, Marco Santacroce, Natalie Roschnik, Aisha Twalibu, Mangani Katundu, Helen Moestue, Harold Alderman, Marie Ruel
Background: Children in Malawi face nutritional risks related to low-quality diets and chronic malnutrition. Objective: This study evaluated the impact of a 1-y early childhood development (ECD) center-based agriculture and nutrition intervention aimed at improving household production diversity, maternal knowledge on child nutrition and feeding practices, and children's diets and anthropometric measures. Methods: A longitudinal cluster-randomized controlled trial was implemented in 60 community-based childcare centers (CBCCs), covering 1248 preschool children (aged 36-72 mo) and 304 younger siblings (aged 6-24 mo)...
September 10, 2018: Journal of Nutrition
Alice Rosi, Daniela Martini, Francesca Scazzina, Elisabetta Dall'Aglio, Roberto Leonardi, Lucilla Monti, Fabrizio Fasano, Cinzia Di Dio, Lucia Riggio, Furio Brighenti
Background: Regular breakfast consumption is associated with better health status and healthier food intake throughout the day, but this association is a complex interaction of several factors. Objective: This study aimed to investigate the effect of nutritional and cognitive-perceived characteristics of breakfast on metabolic and behavioral variables related to food intake. Methods: The study was a randomized, crossover, controlled trial, with 4 experimental conditions consisting of 3 iso-energetic breakfasts and 1 energy-free control meal...
September 10, 2018: Journal of Nutrition
Ling Tao, Tao Sun, Andrew D Magnuson, Tahir R Qamar, Xin Gen Lei
Background: We previously showed enrichments of docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) in broiler chicks fed defatted microalgae. Objectives: The aims of this study were to determine 1) if the enrichments affected meat texture and were enhanced by manipulating dietary corn oil, selenium, and vitamin E concentrations and 2) how the enrichments corroborated with hepatic gene expression involved in biosynthesis and oxidation of EPA and DHA. Methods: Day-old hatching Cornish Giant cockerels (n = 216) were divided into 6 groups (6 cages/group and 6 chicks/cage)...
September 10, 2018: Journal of Nutrition
Suzanne M Hodgkinson, Carlos A Montoya, Patty T Scholten, Shane M Rutherfurd, Paul J Moughan
Background: Cooking processes affect the physical, chemical, and structural properties of meat proteins. Cooking may also affect the protein quality of meat, as indicated by the true ileal digestibility of individual amino acids, the content of each truly digestible amino acid, and the digestible indispensable amino acid score (DIAAS). Objective: The study aimed to determine the effect of the cooking process (raw, not cooked; boiled; grilled; pan-fried; roasted) of beef on true (standardized) ileal amino acid digestibility, true ileal digestible amino acid content, and DIAAS...
September 10, 2018: Journal of Nutrition
Susana L Matias, Malay K Mridha, Rebecca T Young, Sohrab Hussain, Kathryn G Dewey
Background: Maternal anemia and iron deficiency are prevalent in low- and middle-income countries. Objective: We aimed to determine the effects of lipid-based nutrient supplements for pregnant and lactating women (LNS-PL) on hemoglobin (Hb), anemia, and iron status (nonprimary outcomes) at 36 weeks of gestation (women) and 6 mo postpartum (women and infants). Methods: The Rang-Din Nutrition Study, a cluster-randomized effectiveness trial, enrolled 4011 Bangladeshi pregnant women at ≤20 weeks of gestation to receive either daily LNS-PL (20 mg Fe) during pregnancy and the first 6 mo postpartum, or iron and folic acid (IFA, 60 mg Fe + 400 µg folic acid) daily during pregnancy and every other day during the first 3 mo postpartum...
September 10, 2018: Journal of Nutrition
Annette L West, Grete Mørk Kindberg, Svein Olaf Hustvedt, Philip C Calder
Background: A self-micro-emulsifying delivery system (SMEDS) promotes spontaneous emulsification of omega-3 (n-3) ethyl esters (EEs) into microdroplets in the stomach. Objective: The objective was to compare the effect of SMEDS preparations of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) EEs with standard EEs on EPA and DHA concentrations in the bloodstream after a single dose and repeated daily dosing. Methods: Eighty healthy subjects aged 18-65 y were randomly assigned to SMEDS-EPA or EE-EPA (both providing more EPA than DHA) or SMEDS-DHA or EE-DHA (both providing more DHA than EPA)...
September 7, 2018: Journal of Nutrition
Amanda Barks, Stephanie Jb Fretham, Michael K Georgieff, Phu V Tran
Background: Iron deficiency (ID) compromises the developing nervous system, including the hippocampus, resulting in later-life deficits despite iron repletion. The iron-dependent molecular changes driving these lasting deficits, and the effect of early iron repletion, are incompletely understood. Previous studies have utilized dietary models of maternal-fetal ID anemia (IDA) to address these questions; however, concurrent anemia prevents delineation of the specific role of iron. Objective: The aim of the study was to isolate the effects of developmental ID on adult hippocampal gene expression and to determine if iron repletion reverses these effects in a mouse model of nonanemic hippocampal neuronal ID...
August 30, 2018: Journal of Nutrition
Elaine K McCarthy, Deirdre M Murray, Lucio Malvisi, Louise C Kenny, Jonathan O'B Hourihane, Alan D Irvine, Mairead E Kiely
Background: Although animal studies show evidence for a role of vitamin D during brain development, data from human studies show conflicting signals. Objective: We aimed to explore associations between maternal and neonatal vitamin D status with childhood neurodevelopmental outcomes. Methods: Comprehensive clinical, demographic, and lifestyle data were collected prospectively in 734 maternal-infant dyads from the Cork BASELINE Birth Cohort Study...
August 30, 2018: Journal of Nutrition
Laura E Murray-Kolb
No abstract text is available yet for this article.
August 30, 2018: Journal of Nutrition
Sunny S Kim, Phuong Hong Nguyen, Lan Mai Tran, Tina Sanghvi, Zeba Mahmud, Mohammad Raisul Haque, Kaosar Afsana, Edward A Frongillo, Marie T Ruel, Purnima Menon
Background: Sustained improvements in infant and young child feeding (IYCF) require continued implementation of effective interventions. From 2010-2014, Alive & Thrive (A&T) provided intensive interpersonal counseling (IPC), community mobilization (CM), and mass media (MM) in Bangladesh, demonstrating impact on IYCF practices. Since 2014, implementation has been continued and scaled up by national partners with support from other donors and with modifications such as added focus on maternal nutrition and reduced program intensity...
August 29, 2018: Journal of Nutrition
Mariam El Assar, Javier Angulo, Stefan Walter, José Antonio Carnicero, Francisco José García-García, José-María Sánchez-Puelles, Carlos Sánchez-Puelles, Leocadio Rodríguez-Mañas
Background: The expression of certain genes involved in response to oxidative stress is likely related to aging-related outcomes, such as frailty in old age. Given nutrition's substantial impact in aging and age-related diseases, one of its mechanisms might be through influencing gene expression. Objective: This study aimed to investigate the association between nutrition and the expression of 15 genes related to cellular response to stress in older community-dwelling individuals...
September 1, 2018: Journal of Nutrition
Janet C King
No abstract text is available yet for this article.
September 1, 2018: Journal of Nutrition
Bastian Fromm, Juan Pablo Tosar, Yin Lu, Marc K Halushka, Kenneth W Witwer
No abstract text is available yet for this article.
September 1, 2018: Journal of Nutrition
Alyssa M Tindall, Kristina S Petersen, Penny M Kris-Etherton
Clusters of bacterial species within the gut microenvironment, or gut enterotype, have been correlated with cardiometabolic disease risk. The metabolic products and metabolites that bacteria produce, such as short-chain fatty acids, secondary bile acids, and trimethylamine, may also affect the microbial community and disease risk. Diet has a direct impact on the gut microenvironment by providing substrates to and promoting the colonization of resident bacteria. To date, few dietary patterns have been evaluated for their effect on the gut microbiome, but the Mediterranean diet and Vegetarian diets have shown favorable effects for both the gut microbiome and cardiometabolic disease risk...
September 1, 2018: Journal of Nutrition
Xiujuan Lin, Shanshan Li, Yixuan Zou, Feng-Qi Zhao, Jianxin Liu, Hongyun Liu
Background: l-lysine (Lys) is a critical dietary nutrient for mammary gland development and milk production. However, the specific pathways of Lys utilization and how milk protein synthesis is affected in bovine mammary epithelial cells (BMECs) are poorly understood. Objective: We aimed to investigate the effects of Lys on milk protein synthesis and the mechanism of Lys uptake and catabolism in BMECs. Methods: BMECs were cultured in 0, 0.5, 1...
September 1, 2018: Journal of Nutrition
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