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Journal of Nutritional Science and Vitaminology

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#1
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2017: Journal of Nutritional Science and Vitaminology
https://www.readbyqxmd.com/read/29225320/combination-effect-of-%C3%AE-tocotrienol-and-%C3%AE-tocopherol-on-prostate-cancer-cell-growth
#2
Chiaki Sato, Saki Kaneko, Ayami Sato, Nantiga Virgona, Kozue Namiki, Tomohiro Yano
Tocotrienols (T3s) and tocopherols (Tocs) are both members of the vitamin E family. It is known that δ-tocotrienol (δ-T3) has displayed the most potent anti-cancer activity amongst the tocotrienols. On the other hand, γ-tocopherol (γ-Toc) is reported to have a protective effect against prostate cancer. Therefore, we investigated whether the combination of γ-Toc and δ-T3 could strengthen the inhibitory effect of δ-T3 on prostate cancer cell growth. In this study the effect of combined δ-T3 (annatto T3 oil) and γ-Toc (Tmix, γ-Toc-rich oil) therapy was assessed against human androgen-dependent prostate cancer cells (LNCaP)...
2017: Journal of Nutritional Science and Vitaminology
https://www.readbyqxmd.com/read/29225319/effects-of-aerobic-exercise-combined-with-panaxatriol-derived-from-ginseng-on-insulin-resistance-and-skeletal-muscle-mass-in-type-2-diabetic-mice
#3
Yusuke Takamura, Mitsuru Nomura, Akira Uchiyama, Satoshi Fujita
Insulin resistance reduces insulin-induced muscle protein synthesis and accelerates muscle protein degradation. Ginseng ingestion has been reported to improve insulin resistance through the phosphoinositide 3-kinase (PI3K)/Akt signaling pathway. We hypothesized that panaxatriol (PT) derived from ginseng in combination with aerobic exercise (EX) may further promote protein synthesis and suppress protein degradation, and subsequently maintain muscle mass through the amelioration of insulin resistance. KKAy insulin-resistant mice were divided into control, panaxatriol only (PT), exercise only (EX), and EX+PT groups...
2017: Journal of Nutritional Science and Vitaminology
https://www.readbyqxmd.com/read/29225318/caffeine-stimulated-intestinal-epithelial-cells-suppress-lipid-accumulation-in-adipocytes
#4
Takakazu Mitani, Tomoya Nagano, Kiyonari Harada, Yoko Yamashita, Hitoshi Ashida
Caffeine is a methylxanthine derived from plant foods such as coffee beans and tea leaves, and has multiple biological activities against physiological response and several diseases. Although there are some reports about the direct effect of caffeine against anti-lipid accumulation in vitro, the effect of caffeine on lipid accumulation in adipocytes through stimulating intestinal epithelial cells is unknown. Since direct treatment with caffeine to 3T3-L1 cells did not affect lipid accumulation, we determined whether caffeine-stimulated intestinal epithelial Caco-2 cells influence the lipid accumulation in 3T3-L1 adipocytes...
2017: Journal of Nutritional Science and Vitaminology
https://www.readbyqxmd.com/read/29225317/pre-exercise-high-fat-diet-for-3-days-affects-post-exercise-skeletal-muscle-glycogen-repletion
#5
Yumiko Takahashi, Yutaka Matsunaga, Yuki Tamura, Shin Terada, Hideo Hatta
Previous studies have shown that the short-term intake of a high-fat diet (HFD) impairs glucose metabolism. In this study, we investigated the influences of pre-exercise HFD intake for 3 d on post-exercise glycogen repletion in skeletal muscle in ICR mice. Mice received either an HFD (57% kcal from fat, 23% kcal from carbohydrate; HFD group) or standard laboratory chow (13% kcal from fat, 60% kcal from carbohydrate; Con group) for 3 d before exercise. Mice performed treadmill running at 25 m/min for 60 min and were orally administered a glucose (2 mg/g body weight) solution immediately after and at 60 min after exercise...
2017: Journal of Nutritional Science and Vitaminology
https://www.readbyqxmd.com/read/29225316/milk-basic-protein-facilitates-increased-bone-mass-in-growing-mice
#6
Aiko Ono-Ohmachi, Yuko Ishida, Yoshikazu Morita, Ken Kato, Takayuki Y Nara
Milk basic protein (MBP) comprises a group of basic whey proteins and is effective in preventing bone loss by promoting bone deposition (bone formation) and suppressing withdrawn (bone resorption). We previously revealed the bone protective effects of MBP during life phases involving excessive bone resorption, such as in adults and postmenopausal women, and in animal models (ovariectomized rats and mice). However, it was unclear whether MBP increases bone mass during the growth stage, when there is more bone formation than resorption...
2017: Journal of Nutritional Science and Vitaminology
https://www.readbyqxmd.com/read/29225315/comparison-of-the-effects-of-three-tea-cultivars-camellia-sinensis-l-on-nitric-oxide-production-and-aortic-soluble-guanylate-cyclase-expression-in-high-salt-diet-fed-spontaneously-hypertensive-rats
#7
Sachiko Nomura, Manami Monobe, Kaori Ema, Mari Maeda-Yamamoto, Atsushi Nesumi
Studies have suggested that the consumption of green tea reduces the risk of cardiovascular diseases. Although epigallocatechin gallate (EGCG) is the best studied active substance characteristic of green tea, previous results on EGCG do not appear sufficient to explain completely the mechanism of cardiovascular protection by green tea. Therefore, we investigated the effect of three different tea cultivars, "Yabukita," "Sofu," and "Sunrouge," which have characteristic flavonoid compositions, on the nitric oxide (NO) production and the related protein expression in the aorta of spontaneously hypertensive rats (SHRs) fed a high-salt diet...
2017: Journal of Nutritional Science and Vitaminology
https://www.readbyqxmd.com/read/29225314/validity-and-reliability-of-a-general-nutrition-knowledge-questionnaire-for-japanese-adults
#8
Mai Matsumoto, Rie Tanaka, Shinji Ikemoto
Nutrition knowledge is necessary for individuals to adopt appropriate dietary habits, and needs to be evaluated before nutrition education is provided. However, there is no tool to assess general nutrition knowledge of adults in Japan. Our aims were to determine the validity and reliability of a general nutrition knowledge questionnaire for Japanese adults. We developed the pilot version of the Japanese general nutrition knowledge questionnaire (JGNKQ) and administered the pilot study to assess content validity and internal reliability to 1,182 Japanese adults aged 18-64 y...
2017: Journal of Nutritional Science and Vitaminology
https://www.readbyqxmd.com/read/29225313/ingestion-of-coffee-polyphenols-improves-a-scaly-skin-surface-and-the-recovery-rate-of-skin-temperature-after-cold-stress-a-randomized-controlled-trial
#9
Sachie Ueda, Masanori Tanahashi, Yuko Higaki, Kayoko Iwata, Yoshinori Sugiyama
Coffee polyphenols (CPPs) derived from coffee beans have beneficial effects on blood pressure and vascular endothelial function. In addition, CPPs suppress ultraviolet light induced erythema. However, the effects of CPPs on dry skin and cutaneous vascular function have not been clarified. We investigated the effects of CPPs on dry skin and the recovery rate (RR) of skin temperature after a cold-stress test as a measure of vascular function in subjects with visible scaliness in a double-blind, placebo-controlled, randomized study...
2017: Journal of Nutritional Science and Vitaminology
https://www.readbyqxmd.com/read/29225312/prevalence-and-trends-of-vitamin-d-deficiency-among-iranian-adults-a-longitudinal-study-from-2001-2013
#10
Hossein Khosravi-Boroujeni, Nizal Sarrafzadegan, Masoumeh Sadeghi, Hamidreza Roohafza, Shu-Kay Ng, Ali Pourmogaddas, Faruk Ahmed
Vitamin D deficiency/insufficiency is currently considered to be a re-emerging public health problem globally. This study was designed to determine the prevalence of vitamin D deficiency and insufficiency and to investigate its trend from 2001 to 2013 in a longitudinal study of Iranian adults. This study was part of a population-based, longitudinal ongoing study of Iranian healthy adults aged 35 y and older at baseline. Serum vitamin D level was assessed in a sub-sample of 370 subjects, who were apparently healthy at the time of recruitment in 2001 and were free from MetS, in three phases (2001, 2007 and 2013) during the 12-y study period...
2017: Journal of Nutritional Science and Vitaminology
https://www.readbyqxmd.com/read/29225311/inhibition-of-oxidative-stress-by-antioxidant-supplementation-does-not-limit-muscle-mitochondrial-biogenesis-or-endurance-capacity-in-rats
#11
Jae Cheol Kim, Gi Duck Park, Sang Hyun Kim
The objective of the present study was to analyze the activation and expression patterns of upstream and downstream factors of PGC-1α to determine whether antioxidant (AO) supplementation inhibits mitochondrial biogenesis in skeletal muscles as an adaptation to endurance training, as well as to analyze changes in endurance capacity based on such findings. For this objective, 24 male Sprague-Dawley (SD) rats were allocated into 4 groups (vehicle-sedentary, V-Sed; vehicle-exercise, V-EX; antioxidant-sedentary, AO-Sed; antioxidant-exercise, AO-EX) of 6 rats each...
2017: Journal of Nutritional Science and Vitaminology
https://www.readbyqxmd.com/read/29225208/dietary-calcium-and-serum-25ohd-protect-chinese-women-from-type-2-diabetes
#12
Lijun Feng, Zhefang Hu, Qingqing Wang
The Chinese dietary structure is different from Western and Mediterranean diets. This study aimed to assess the association of dietary calcium, serum 25-hydroxyvitamin D (25OHD), and other macronutrients with type 2 diabetes (T2D) in Chinese patients. This case-control study enrolled 605 patients (males, 337; females, 268) with T2D and 724 healthy subjects (males, 405; females, 319) at Sir Run Run Shaw Hospital from February to April 2014. Dietary calcium, total energy, fat to energy ratio, glucose administration, 2-h postprandial blood glucose, serum total cholesterol and high density lipoprotein (HDL)-cholesterol, and serum 25OHD level were assessed...
2017: Journal of Nutritional Science and Vitaminology
https://www.readbyqxmd.com/read/28978875/agaro-oligosaccharides-regulate-gut-microbiota-and-adipose-tissue-accumulation-in-mice
#13
Yasuki Higashimura, Yasunori Baba, Ryo Inoue, Tomohisa Takagi, Katsura Mizushima, Hiromu Ohnogi, Akira Honda, Yasushi Matsuzaki, Yuji Naito
Gut microbiota are deeply associated with the prevalence of obesity. Agarose is hydrolyzed easily to yield oligosaccharides, designated as agaro-oligosaccharides (AGO). This study evaluated the effects of AGO on obese phenotype and gut microbial composition in mice. Mice were administered AGO in drinking water (AGO-receiving mice). 16S rRNA gene sequencing analyses revealed their fecal microbiota profiles. Serum bile acids were ascertained using a LC-MS/MS system. Compared to the control group, AGO administration significantly reduced epididymal adipose tissue weights and serum non-esterified fatty acid concentrations, but the cecal content weights were increased...
2017: Journal of Nutritional Science and Vitaminology
https://www.readbyqxmd.com/read/28978874/aphanothece-sacrum-sur-okada-prevents-cataractogenesis-in-type-1-diabetic-mice
#14
Shiori Matsuda, Hikari Sugawa, Jun-Ichi Shirakawa, Rei-Ichi Ohno, Sho Kinoshita, Kenta Ichimaru, Shoutaro Arakawa, Mime Nagai, Kiyotaka Kabata, Ryoji Nagai
Aphanothece sacrum (Sur.) Okada is a species of cyanobacteria found in Japan. Although it has been used in local cuisine in Kyushu, Japan, for 250 y, little is known about its beneficial effect as food. The daily intake of health beneficial phytochemicals is believed to be useful for preventing lifestyle-related diseases, such as diabetic cataracts. In this study, the inhibitory effect of freeze-dried A. sacrum (Asa) on the formation of diabetic cataracts (DCs) was evaluated. Type 1 diabetes was induced in mice using streptozotocin (STZ)...
2017: Journal of Nutritional Science and Vitaminology
https://www.readbyqxmd.com/read/28978873/cooking-methods-for-a-soft-diet-using-chicken-based-on-food-texture-analysis
#15
Emi Watanabe, Masami Maeno, Jun Kayashita, Ken-Ichi Miyamoto, Miho Kogirima
Undernutrition caused by difficulties in masticating is of growing concern among the elderly. Soft diets are often served at nursing homes; however, the styles differ with nursing homes. Improperly modified food texture and consistency may lead to further loss of nutritive value. Therefore, we developed a method to produce a soft diet using chicken. The texture-modified chicken was prepared by boiling a mixture of minced chicken and additive foodstuff that softened the meat. The best food additive was determined through testing cooking process, size after modification and texture...
2017: Journal of Nutritional Science and Vitaminology
https://www.readbyqxmd.com/read/28978872/the-impact-of-menstrual-cycle-phases-on-cardiac-autonomic-nervous-system-activity-an-observational-study-considering-lifestyle-diet-physical-activity-and-sleep-among-female-college-students
#16
Yuki Tada, Takahiro Yoshizaki, Yasutake Tomata, Yuri Yokoyama, Ayaka Sunami, Azumi Hida, Yukari Kawano
Studies examining the impact of menstrual cycle phases on the cardiac autonomic nervous system have produced inconsistent results. This study aimed to investigate this relationship, controlling for the confounding effects of diet, physical activity, and sleep, which can be affected by the menstrual cycle. Fifteen female college students with regular menses were enrolled. Data regarding 24-h heart rate variability (HRV), dietary intake, eating behavior, menstrual distress, and sleep and activity parameters were obtained during the follicular and luteal phases...
2017: Journal of Nutritional Science and Vitaminology
https://www.readbyqxmd.com/read/28978871/co-administration-of-myostatin-targeting-sirna-and-actriib-fc-fusion-protein-increases-masseter-muscle-mass-and-fiber-size
#17
Od Bayarsaikhan, Nobuhiko Kawai, Hiroyo Mori, Nao Kinouchi, Takeshi Nikawa, Eiji Tanaka
Myostatin, a member of the TGF-β superfamily, is a negative regulator of skeletal muscle cell growth and differentiation, and binds with high affinity to the activin type IIB receptor (ActRIIB). The soluble ligand-binding domain of ActRIIB fused to the Fc domain of IgG (ActRIIB-Fc) potently binds and inhibits TGF-β family members in muscle, leading to rapid and marked muscle growth. The present study was designed to assess the effectiveness of the co-delivery of myostatin-targeting siRNA (Mstn-siRNA) and ActRIIB-Fc into skeletal muscle as a potential treatment of atrophic myopathies...
2017: Journal of Nutritional Science and Vitaminology
https://www.readbyqxmd.com/read/28978870/anthocyanin-cyanidin-3-glucoside-attenuates-platelet-granule-release-in-mice-fed-high-fat-diets
#18
Fang-Hang Zhou, Xiu-Juan Deng, Yan-Qiu Chen, Fu-Li Ya, Xian-Dan Zhang, Fenglin Song, Dan Li, Yan Yang
Platelet granule release is considered an important target for preventing and treating cardiovascular diseases (CVDs). Cyanidin-3-glucoside (Cy-3-g) is a predominant bioactive anthocyanin compound in many edible plants and has been reported to be protective against CVDs by attenuating platelet dysfunction. However, direct evidence of the action of Cy-3-g on platelet granule secretion in purified platelets from in vivo assays is still poor. In the present study, we demonstrated that dietary supplementation of purified Cy-3-g reduces serum lipid levels and facilitates down-regulation of the platelet granule release of substances such as P-selectin, CD40L, 5-HT, RANTES and TGF-β1 in gel-filtered platelets, in addition to attenuating serum PF4 and β-TG levels in mice fed high-fat diets...
2017: Journal of Nutritional Science and Vitaminology
https://www.readbyqxmd.com/read/28978869/vitamin-d-receptor-gene-variation-dietary-intake-and-bone-mineral-density-in-obese-women-a-cross-sectional-study
#19
Sajjad Moradi, Leila Khorrami-Nezhad, Zhila Maghbooli, Banafshe Hosseini, Seyed Ali Keshavarz, Khadijeh Mirzaei
Osteoporosis and fragility fractures have been regarded as important public health concerns. We investigated their possible association with vitamin D receptor (VDR) FOK1 polymorphisms (rs10735810) and dietary parameters such as calcium and vitamin D intake. A total of 264 Iranian obese women (BMI>30 kg/m(2)) were categorized based on the FOK1 genotype and divided into two groups: group one with the FF genotype (n=184) and the f allele carrier group with the Ff or ff genotype (n=80). The body composition, dietary intake and bone mineral density were assessed for all cases...
2017: Journal of Nutritional Science and Vitaminology
https://www.readbyqxmd.com/read/28978868/advances-in-genetic-improvement-for-tocotrienol-production-a-review
#20
Sulaiman Rufai Babura, Siti Nor Akmar Abdullah, Huzwah Khaza Ai
Tocotrienols are forms of vitamin E that are present in several important food crops. Compared to tocopherols, less research has been conducted on these compounds because of their low bioavailability and distribution in plant tissues. Both tocotrienols and tocopherols are known for their antioxidant and anticancer activities, which are beneficial for both humans and animals. Moreover, tocotrienols possess certain properties which are not found in tocopherols, such as neuroprotective and cholesterol-lowering activities...
2017: Journal of Nutritional Science and Vitaminology
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