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Progress in Biophysics and Molecular Biology

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https://www.readbyqxmd.com/read/30615891/bioremediation-potential-of-waste-biomaterials-originating-from-coastal-zostera-marina-l-meadows-for-polluted-aqueous-media-with-industrial-effluents
#1
Fatih Deniz
The studies on novel and efficient biosorbent materials for the promotion of environmental and economic sustainability have been become an up-to-date attempt by scientists for the removal of synthetic dyes from industrial effluents. The biosorbents prepared from biomass based resources are emerging as an alternative promising material for the environmental clean-up because of their low-cost, renewability, eco-friendly, easy availability and so forth characteristics. Hence, for the first time, the biosorption performance of abundantly available natural biowastes originating from coastal Zostera marina L...
January 4, 2019: Progress in Biophysics and Molecular Biology
https://www.readbyqxmd.com/read/30612704/protocells-and-luca-transport-of-substances-from-first-physicochemical-principles
#2
REVIEW
Alexey V Melkikh, Maria Sutormina
Models of the transport of substances in protocells are considered from first physicochemical principles. Functional similarities and differences in the transport systems of archaea, cyanobacteria, E. coli, and diatoms have been analyzed. Based on the selection of the most important transport systems, a model of transport of substances through the membrane of the last universal common ancestor, LUCA, was constructed. Models of isotope separation in protocells were considered. Based on the proposed models, the difference in isotope concentrations in rocks can be predicted, which can serve as an indicator of the presence of life in the early stages of evolution...
January 3, 2019: Progress in Biophysics and Molecular Biology
https://www.readbyqxmd.com/read/30605640/investigation-of-caffeine-taste-mechanism-through-a-statistical-physics-modeling-of-caffeine-dose-taste-response-curve-by-a-biological-putative-caffeine-adsorption-process-in-electrophysiological-response
#3
Amel Nakbi, Mohamed Bouzid, Fakher Ayechi, Fatma Aouaini, Abdelmottaleb Ben Lamine
This work is a contribution to understand the taste mechanism of caffeine molecule using a modeling of a putative adsorption process by model expressions established by a statistical physics treatment. A physicochemical and a gustative parts are the main constituents of this work. We start with a physicochemical investigation of the adsorption process of caffeine molecule, as adsorbate in liquid phase, onto β-cyclodextrin as adsorbent. Experimental adsorption isotherm curves of caffeine onto β-cyclodextrin coated onto Quartz crystal are carried out at three different temperatures...
December 31, 2018: Progress in Biophysics and Molecular Biology
https://www.readbyqxmd.com/read/30597150/circadian-leaf-movements-facilitate-overtopping-of-neighbors
#4
Michael A Woodley Of Menie, Piotr Pawlik, Matthew T Webb, Kenneth D Bruce, Paul F Devlin
Many plants exhibit circadian clock-driven leaf movements whereby the leaves are raised during the day to achieve a relatively high angle during the evening, before lowering late in the night. Such leaf movements were first recorded over 2000 years ago but there is still much debate as to their purpose. We investigated whether such leaf movements within Arabidopsis, a ruderal rosette plant, can aid in overtopping leaves of neighboring plants. Wild type and circadian clock mutant plants were grown in an alternating grid system so that their leaves would meet as the plants grew...
December 28, 2018: Progress in Biophysics and Molecular Biology
https://www.readbyqxmd.com/read/30590094/editorial
#5
EDITORIAL
Noble Dennis
No abstract text is available yet for this article.
December 24, 2018: Progress in Biophysics and Molecular Biology
https://www.readbyqxmd.com/read/30579630/engineering-hipsc-cardiomyocyte-in-vitro-model-systems-for-functional-and-structural-assessment
#6
REVIEW
Alison Schroer, Gaspard Pardon, Erica Castillo, Cheavar Blair, Beth Pruitt
The study of human cardiomyopathies and the development and testing of new therapies has long been limited by the availability of appropriate in vitro model systems. Cardiomyocytes are highly specialized cells whose internal structure and contractile function are sensitive to the local microenvironment and the combination of mechanical and biochemical cues they receive. The complementary technologies of human induced pluripotent stem cell (hiPSC) derived cardiomyocytes (CMs) and microphysiological systems (MPS) allow for precise control of the genetics and microenvironment of human cells in in vitro contexts...
December 19, 2018: Progress in Biophysics and Molecular Biology
https://www.readbyqxmd.com/read/30562539/decoding-systems-biology-of-plant-stress-for-sustainable-agriculture-development-and-optimized-food-production
#7
REVIEW
Khader Shameer, Mahantesha B N Naika, K Mohamed Shafi, Ramanathan Sowdhamini
Plants are essential facilitators of human life on planet earth. Plants play a critical functional role in mediating the quality of air, availability of food and the sustainability of agricultural resources. However, plants are in constant interaction with its environment and often hampered by various types of stresses like biotic and abiotic ones. Biotic stress is a significant reason for crop-loss and causes yield loss in the range of 31-42%, post-harvest loss due to biotic stress is in the range of 6-20%, and abiotic stress causes 6-20% of the crop damage...
December 15, 2018: Progress in Biophysics and Molecular Biology
https://www.readbyqxmd.com/read/30557534/the-golden-section-and-beauty-in-nature-the-perfection-of-symmetry-and-the-charm-of-asymmetry
#8
REVIEW
Ulrich Lüttge, G M Souza
It is not unanimous among scientists if there is beauty in science. Some deny it. Mental clarity of conclusions when captured in simple looking equations is mathematical beauty. This we also find in the Euclidian geometry when performing the Golden Section and by deriving the Golden or Devine Number in golden rectangles, spirals and the Golden Angle. The Golden Section is considered as most beautiful and used in architecture and art. It is found everywhere in nature, e.g. in the pentagram of flowers, in the spirals of the shells of snails and Nautilus and even in galaxies of space...
December 14, 2018: Progress in Biophysics and Molecular Biology
https://www.readbyqxmd.com/read/30557533/rooting-of-eucalypt-cuttings-as-a-problem-solving-oriented-model-in-plant-biology
#9
REVIEW
Johnatan Vilasboa, Cibele Tesser da Costa, Arthur Germano Fett-Neto
Species of Eucalyptus are some of the most planted trees in the world, providing fiber, cellulose, energy, and wood for construction and furniture in renewable fashion, with the added advantage of fixing large amounts of atmospheric carbon. The efficiency of eucalypts in forestry relies mostly on the clonal propagation of selected genotypes both as pure species and interspecific hybrids. The formation of new roots from cambium tissues at the base of cuttings, referred to as adventitious rooting (AR), is essential for accomplishing clonal propagation successfully...
December 14, 2018: Progress in Biophysics and Molecular Biology
https://www.readbyqxmd.com/read/30553754/uncovering-metastability-and-disassembly-hotspots-in-whole-viral-particles
#10
Ranita Ramesh, Xin Xiang Lim, Palur Venkata Raghuvamsi, Wu Chao, Wong Sek Man, Ganesh Srinivasan Anand
Viruses are metastable macromolecular assemblies that toggle between multiple conformational states through molecular rearrangements that are critical for mediating viral host entry. Viruses respond to different host specific environmental cues to form disassembly intermediates for the eventual release of genomic material required for replication. Although static snapshots of these intermediates have been captured through structural techniques such as X-ray crystallography and cryo-EM, the mechanistic details of these conformational rearrangements underpinning viral metastability have been poorly understood...
December 13, 2018: Progress in Biophysics and Molecular Biology
https://www.readbyqxmd.com/read/30553553/agonistic-and-antagonistic-roles-of-fibroblasts-and-cardiomyocytes-on-viscoelastic-stiffening-of-engineered-human-myocardium
#11
Susanne F Schlick, Florian Spreckelsen, Malte Tiburcy, Lavanya M Iyer, Tim Meyer, Laura C Zelarayan, Stefan Luther, Ulrich Parlitz, Wolfram-Hubertus Zimmermann, Florian Rehfeldt
Cardiomyocyte and stroma cell cross-talk is essential for the formation of collagen-based engineered heart muscle, including engineered human myocardium (EHM). Fibroblasts are a main component of the myocardial stroma. We hypothesize that fibroblasts, by compacting the surrounding collagen network, support the self-organization of cardiomyocytes into a functional syncytium. With a focus on early self-organization processes in EHM, we studied the molecular and biophysical adaptations mediated by defined populations of fibroblasts and embryonic stem cell-derived cardiomyocytes in a collagen type I hydrogel...
December 12, 2018: Progress in Biophysics and Molecular Biology
https://www.readbyqxmd.com/read/30550737/a-structural-and-functional-perspective-on-the-enzymes-of-mycobacterium-tuberculosis-involved-in-the-l-rhamnose-biosynthesis-pathway
#12
Devendra K Dhaked, M Bala Divya, Lalitha Guruprasad
Tuberculosis is one of the leading causes of death from bacterial infections. The multi-drugresistant strain has warranted the development of new drug molecules which can inhibit the growth of Mycobacterium tuberculosis. Most of the known drugs inhibit the enzymes in the cell wall biosynthesis. One of such pathway is L-rhamnose, which involves four druggableenzymes RmlA, B, C and D. The 3D structure analyses of these protein models (RmlA, B and D) and crystal structure (RmlC) has been carried out. Multiple sequence alignments of homologs from distant species of 32 taxa and analyses of available structures were performed in order to study the conservation of sequence and structural motifs, and catalytically important residues...
December 11, 2018: Progress in Biophysics and Molecular Biology
https://www.readbyqxmd.com/read/30543828/molecular-binding-response-of-naringin-and-naringenin-to-h46r-mutant-sod1-protein-in-combating-protein-aggregation-using-density-functional-theory-and-discrete-molecular-dynamics
#13
E Srinivasan, R Rajasekaran
Amyotrophic lateral sclerosis (ALS) is a calamitous neurodegenerative disorder characterized by denervation of upper and lower motor neurons. Numerous hypotheses suggest that toxic protein misfolding and aggregation cause ALS, similar to that of other neurodegenerative diseases, such as Alzheimers and Parkinsons. Protruding causes of familial ALS are mutations in the gene encoding Cu/Zn superoxide dismutase-1 (SOD1), which decrease protein stability and endorse protein aggregation. Thus, the interference concerning aggregate formation and destabilization in SOD1 is considered to be an impending therapeutic strategy...
December 10, 2018: Progress in Biophysics and Molecular Biology
https://www.readbyqxmd.com/read/30528740/structural-basis-for-renal-cancer-by-the-dynamics-of-pvhl-dependent-jade1-stabilization-and-%C3%AE-catenin-regulation
#14
Shagufta Shafique, Sajid Rashid
Renal cancer is the major cause of mortality due to abnormal functioning of von Hippel-Lindau (pVHL) and Jade Family PHD Finger 1 (JADE1) complex. E3 ubiquitin ligase JADE1 is stabilized by pVHL interaction through its plant homeodomains (PHDs). JADE1 acts as a renal tumor suppressor that promotes the ubiquitination and degradation of β-catenin by inhibiting canonical WNT signalling. Current study focuses on the structural characterization of reported missense mutations in pVHL through in silico approaches...
December 7, 2018: Progress in Biophysics and Molecular Biology
https://www.readbyqxmd.com/read/30508537/long-distance-electrical-signals-as-a-link-between-the-local-action-of-stressors-and-the-systemic-physiological-responses-in-higher-plants
#15
REVIEW
Vladimir Sukhov, Ekaterina Sukhova, Vladimir Vodeneev
Our review is devoted to the analysis of the role of long-distance electrical signals in the development of the fast systemic physiological responses in higher plants. The characteristics and mechanisms of basic electrical signals (variation potential, action potential and system potential) are analyzed, and a potential schema of the generation and propagation of the system potential is proposed. The review summarizes the physiological changes induced by the variation potential, action potential and system potential in higher plants, including changes in gene expressions, the production of phytohormones, photosynthesis, phloem mass-flow, respiration, ATP content, transpiration and plant growth...
November 30, 2018: Progress in Biophysics and Molecular Biology
https://www.readbyqxmd.com/read/30500339/low-level-laser-therapy-lllt-modulates-ovarian-function-in-mature-female-mice
#16
Gonzalo Oubiña, Natalia Pascuali, Leopoldina Scotti, Mariana Di Pietro, Florenza A La Spina, Mariano G Buffone, Javier Higuera, Dalhia Abramovich, Fernanda Parborell
It is known that LLLT has beneficial effects on several pathological conditions including wound healing, pain and inflammation. LLLT modulates biological processes, including cell proliferation, apoptosis and angiogenesis. In the present study, we examined the effect of local application of LLLT on follicular dynamics, ovarian reserve, AMH expression, progesterone levels, apoptosis, angiogenesis, and reproductive outcome in adult mice. LLLT (200 J/cm2 ) increased the percentage of primary and preantral follicles, whilst decreasing the percentage of corpora lutea compared to control ovaries...
November 27, 2018: Progress in Biophysics and Molecular Biology
https://www.readbyqxmd.com/read/30458181/the-guard-cell-ionome-understanding-the-role-of-ions-in-guard-cell-functions
#17
REVIEW
Biswapriya B Misra, Suzie M Reichman, Sixue Chen
The plant ionome is critical for growth, productivity, defense, and it eventually affects food quantity and quality. Located on the leaf surface, stomatal guard cells are critical gatekeepers for water, gas, and pathogens. Insights form ionomics (metallomics) is imperative as we enter an omics-driven systems biology era where an understanding of guard cell function and physiology is advanced through efforts in genomics, transcriptomics, proteomics, and metabolomics. While the roles of major cations (K, Ca) and anions (Cl) are well known in guard cell function, the related physiology, movement and regulation of trace elements, metal ions, and heavy metals are poorly understood...
November 17, 2018: Progress in Biophysics and Molecular Biology
https://www.readbyqxmd.com/read/30448076/corrigendum-to-limitations-in-electrophysiological-model-development-and-validation-caused-by-differences-between-simulations-and-experimental-protocols-prog-biophys-mol-biol-129-2017-53-64
#18
Jesús Carro, José F Rodríguez-Matas, Violeta Monasterio, Esther Pueyo
No abstract text is available yet for this article.
November 14, 2018: Progress in Biophysics and Molecular Biology
https://www.readbyqxmd.com/read/30447225/insights-into-aba-mediated-regulation-of-guard-cell-primary-metabolism-revealed-by-systems-biology-approaches
#19
Takuya Yoshida, Letícia Dos Anjos, David B Medeiros, Wagner L Araújo, Alisdair R Fernie, Danilo M Daloso
Despite the fact that guard cell abscisic acid (ABA) signalling pathway is well documented, our understanding concerning how and to which extent ABA regulates guard cell metabolism remains fragmentary. Here we have adopted different systems approaches to investigate how ABA modulates guard cell central metabolism by providing genes that are possibly ABA-regulated. By using previous published Arabidopsis guard cell transcript profiling data, we carried out an extensive co-expression network analysis using ABA-related genes and those related to the metabolism and transport of sugars, starch and organic acids...
November 14, 2018: Progress in Biophysics and Molecular Biology
https://www.readbyqxmd.com/read/30444975/thermodynamic-buffering-stable-non-equilibrium-and-establishment-of-the-computable-structure-of-plant-metabolism
#20
REVIEW
Abir U Igamberdiev, Leszek A Kleczkowski
The equilibria of coenzyme nucleotides and substrates established in plant cells generate simple rules that govern the plant metabolome and provide optimal conditions for the non-equilibrium fluxes of major metabolic processes such as ATP synthesis, CO2 fixation, and mitochondrial respiration. Fast and abundant enzymes, such as adenylate kinase, carbonic anhydrase or malate dehydrogenase, provide constant substrate flux for these processes. These "buffering" enzymes follow the Michaelis-Menten (MM) kinetics and operate near equilibrium...
November 13, 2018: Progress in Biophysics and Molecular Biology
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