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Journal of Radiation Research

Shunta Jinno, Hidenobu Tachibana, Shunsuke Moriya, Norifumi Mizuno, Ryo Takahashi, Tatsuya Kamima, Satoru Ishibashi, Masanori Sato
In inhomogeneous media, there is often a large systematic difference in the dose between the conventional Clarkson algorithm (C-Clarkson) for independent calculation verification and the superposition-based algorithms of treatment planning systems (TPSs). These treatment site-dependent differences increase the complexity of the radiotherapy planning secondary check. We developed a simple and effective method of heterogeneity correction integrated with the Clarkson algorithm (L-Clarkson) to account for the effects of heterogeneity in the lateral dimension, and performed a multi-institutional study to evaluate the effectiveness of the method...
May 21, 2018: Journal of Radiation Research
Naoki Nakamura, Hidehiro Hojo, Kazuya Inoue, Kenji Hotta, Sadamoto Zenda, Hiromi Baba, Masakatsu Onozawa, Atsushi Motegi, Masaki Nakamura, Yuichi Kibe, Tetsuo Akimoto
This study aimed to examine late radiological changes after proton beam therapy (PBT) for early-stage non-small cell lung cancer (NSCLC) and to clarify correlations between mass-like radiological changes and patient characteristics. CT scans of patients who underwent passive scattering PBT for T1-2N0M0 NSCLC were analyzed retrospectively. Patients were considered eligible if follow-up CT was performed for at least 2 years, with no definite evidence of local recurrence. The following five periods were defined: (i) 6-12 months, (ii) 12-24 months, (iii) 24-36 months, (iv) 36-48 months and (v) 48-60 months after PBT...
May 21, 2018: Journal of Radiation Research
Yukihisa Tamaki, Tomoko Itazawa, Takafumi Komiyama, Yasumasa Nishimura, Yuko Nakayama, Hiroyuki Ito, Yasuhisa Ohde, Masahiko Kusumoto, Shuji Sakai, Kenji Suzuki, Hirokazu Watanabe, Hisao Asamura
No abstract text is available yet for this article.
May 19, 2018: Journal of Radiation Research
Chawalit Lertbutsayanukul, Sarin Kitpanit, Anussara Prayongrat, Danita Kannarunimit, Buntipa Netsawang, Chakkapong Chakkabat
This study aimed to validate previously reported dosimetric parameters, including thyroid volume, mean dose, and percentage thyroid volume, receiving at least 40, 45 and 50 Gy (V40, V45 and V50), absolute thyroid volume spared (VS) from 45, 50 and 60 Gy (VS45, VS50 and VS60), and clinical factors affecting the development of radiation-induced hypothyroidism (RHT). A post hoc analysis was performed in 178 euthyroid nasopharyngeal cancer (NPC) patients from a Phase III study comparing sequential versus simultaneous-integrated boost intensity-modulated radiation therapy...
May 10, 2018: Journal of Radiation Research
Nana Sato, Makiko Orita, Yasuyuki Taira, Noboru Takamura
No abstract text is available yet for this article.
April 30, 2018: Journal of Radiation Research
Hiraku Iramina, Takumi Hamaguchi, Mitsuhiro Nakamura, Takashi Mizowaki, Ikuo Kanno
We evaluated two dual-energy cone-beam computed tomography (DE-CBCT) methodologies for a bench-top micro-CBCT system to reduce metal artifacts on reconstructed images. Two filter-based DE-CBCT methodologies were tested: (i) alternative spectral switching and (ii) simultaneous beam splitting. We employed filters of 0.6-mm-thick tin and 0.1-mm-thick tungsten to generate high- and low-energy spectra from 120 kVp X-rays, respectively. The spectral switching method was imitated by two half scans with different filters (pseudo-switching)...
April 30, 2018: Journal of Radiation Research
Kazuhiko Sato, Hiromi Fuchikami, Naoko Takeda, Masahiro Kato, Takahiro Shimo, Tomohiko Okawa
Based on the accumulating evidence for equivalent results of partial-breast irradiation (PBI) and whole-breast irradiation (WBI) in breast-conserving therapy (BCT), the American Society for Radiation Oncology (ASTRO) updated the consensus statement (CS) to expand the range of potential candidates for PBI outside clinical trials. Of the various techniques, PBI using multicatheter interstitial brachytherapy (MCB) is the oldest and has long-term data. In this study, the efficacy of single-stage BCT using MCB-PBI achieved by an intraoperative catheter placement was validated on updated ASTRO guidelines...
April 25, 2018: Journal of Radiation Research
(no author information available yet)
No abstract text is available yet for this article.
April 24, 2018: Journal of Radiation Research
Aydemir Kale, Özcan Piskin, Yilmaz Bas, Bengü Gülhan Aydin, Murat Can, Özlem Elmas, Çagatay Büyükuysal
Extensive research has been focused on radiation-induced brain injury. Animal and human studies have shown that flavonoids have remarkable toxicological profiles. This study aims to investigate the neuroprotective effects of quercetin in an experimental radiation-induced brain injury. A total of 32 adult male Wistar-Albino rats were randomly divided into four groups (control, quercetin, radiation, and radiation+quercetin groups, with eight rats in each group). Doses (50 mg/kg) of quercetin were administered to the animals in the quercetin and radiation+quercetin groups; radiation and radiation+quercetin groups were exposed to a dose of 20 Gy to the cranium region...
April 24, 2018: Journal of Radiation Research
Hiroshi Nukui, Sanae Midorikawa, Michio Murakami, Masaharu Maeda, Akira Ohtsuru
Work-related mental health impairment is recognized as a real problem in the context of helping responders, including health professionals, due to adverse health outcomes after a severe disaster. The Great East-Japan Earthquake, which occurred on 11 March 2011, was an unprecedented complex disaster that caused a nuclear accident at the Fukushima Daiichi Nuclear Power Plant (NPP). In addition to disaster stress and daily work, medical and health-care professionals, particularly nurses, provided counseling services to residents concerned about radiation health risks or mental health issues...
April 13, 2018: Journal of Radiation Research
Kenichi Tanaka, Tsuyoshi Kajimoto, Takahiro Hayashi, Osamu Asanuma, Masakazu Hori, Ken-Ichi Kamo, Iori Sumida, Yutaka Takahashi, Kunihiko Tateoka, Gerard Bengua, Koh-Ichi Sakata, Satoru Endo
This study aims to demonstrate the feasibility of a method for estimating the strength of a moving brachytherapy source during implantation in a patient. Experiments were performed under the same conditions as in the actual treatment, except for one point that the source was not implanted into a patient. The brachytherapy source selected for this study was 125I with an air kerma strength of 0.332 U (μGym2h-1), and the detector used was a plastic scintillator with dimensions of 10 cm × 5 cm × 5 cm. A calibration factor to convert the counting rate of the detector to the source strength was measured and then the accuracy of the proposed method was investigated for a manually driven source...
April 11, 2018: Journal of Radiation Research
Masahiro Inada, Hajime Monzen, Kenji Matsumoto, Mikoto Tamura, Takafumi Minami, Kiyoshi Nakamatsu, Yasumasa Nishimura
Tungsten functional paper (TFP) is a paper-based radiation-shielding material, which is lead-free and easy to cut. We developed a radiation protection undergarment using TFP for prostate cancer patients treated with permanent 125I seed implantation (PSI). The aim of this study was to evaluate the shielding ability of the undergarment with respect to household contacts and members of the public. Between October 2016 and April 2017, a total of 10 prostate cancer patients treated with PSI were enrolled in this prospective study...
April 11, 2018: Journal of Radiation Research
Noriko Takata, Masaaki Kataoka, Yasushi Hamamoto, Shintaro Tsuruoka, Hiromitsu Kanzaki, Kotaro Uwatsu, Kei Nagasaki, Teruhito Mochizuki
Pericardial effusion is an important late toxicity after concurrent chemoradiotherapy (CCRT) for locally advanced esophageal cancer. We investigated the clinical and dosimetric factors that were related to pericardial effusion among patients with thoracic esophageal cancer who were treated with definitive CCRT using the two opposed fields technique (TFT) or the four-field technique (FFT), as well as the effectiveness of FFT. During 2007-2015, 169 patients with middle and/or lower thoracic esophageal cancer received definitive CCRT, and 94 patients were evaluable (51 FFT cases and 43 TFT cases)...
April 11, 2018: Journal of Radiation Research
Arifumi Hasegawa, Manami Takahashi, Mami Nemoto, Takashi Ohba, Chieri Yamada, Shiro Matsui, Mitsuko Fujino, Kenichi Satoh
Although many experts have attempted communication about radiation risk, fears about radiation exposure stemming from the Fukushima Daiichi Nuclear Power Plant accident remain deeply rooted. The characteristics of the anxiety vary with social background, which makes it difficult to alleviate with one approach. Our ultimate goal is therefore to create risk-communication materials tailored to various groups with differing social backgrounds. Towards that end, the purpose of the present study was to clarify potential factors associated with radiation-related anxieties within these groups...
April 10, 2018: Journal of Radiation Research
Toyoaki Sawano, Yoshitaka Nishikawa, Akihiko Ozaki, Claire Leppold, Masaharu Tsubokura
The health threats of radiation-release incidents are diverse and long term. In addition to direct radiation effects, it is imperative to manage the indirect effects of radiation such as stigma, prejudice and broader mental health impacts. Six years after the Fukushima Daiichi Nuclear Power Plant accident of March 2011, bullying caused by stigma and prejudice toward evacuees, including children, has become a social problem in Japan. This phenomenon may be associated with the fact that knowledge about radiation has still not reached the general public, and to a potential lack of motivation among Japanese citizens to learn about radiation and bullying...
April 9, 2018: Journal of Radiation Research
Takeshi Iimoto, Hirofumi Fujii, Seiichi Someya, Hajime Matsuzawa, Yukihide Yanagawa, Kiyoshi Kunii
Kashiwa city, inside the Tokyo metropolitan area and located ~200 km south of the Fukushima Dai-ichi Nuclear Power Plant, received a raised environmental ambient radiation dose due to the disaster relative to the rest of area. In this paper, the challenging process of the official voluntary decontamination activity in Kashiwa city, Chiba prefecture, which was carried out with strong cooperation between a local government and experts, is described and reviewed in terms of the effectiveness of the radiation protection...
April 6, 2018: Journal of Radiation Research
Asuka Oyama, Shinobu Kumagai, Norikazu Arai, Takeshi Takata, Yusuke Saikawa, Kenshiro Shiraishi, Takenori Kobayashi, Jun'ichi Kotoku
This study was conducted to improve cone-beam computed tomography (CBCT) image quality using the super-resolution technique, a method of inferring a high-resolution image from a low-resolution image. This technique is used with two matrices, so-called dictionaries, constructed respectively from high-resolution and low-resolution image bases. For this study, a CBCT image, as a low-resolution image, is represented as a linear combination of atoms, the image bases in the low-resolution dictionary. The corresponding super-resolution image was inferred by multiplying the coefficients and the high-resolution dictionary atoms extracted from planning CT images...
April 5, 2018: Journal of Radiation Research
Jin Seo Park, Yong Wook Jung, Hyung-Do Choi, Ae-Kyoung Lee
The anatomical structures in most phantoms are classified according to tissue properties rather than according to their detailed structures, because the tissue properties, not the detailed structures, are what is considered important. However, if a phantom does not have detailed structures, the phantom will be unreliable because different tissues can be regarded as the same. Thus, we produced the Visible Korean (VK) -phantoms with detailed structures (male, 583 structures; female, 459 structures) based on segmented images of the whole male body (interval, 1...
April 5, 2018: Journal of Radiation Research
Takakiyo Tsujiguchi, Hideki Obara, Shuichi Ono, Yoko Saito, Ikuo Kashiwakura
Computed tomography (CT) has recently been utilized in various medical settings, and technological advances have resulted in its widespread use. However, medical radiation exposure associated with CT scans accounts for the largest share of examinations using radiation; thus, it is important to understand the organ dose and effective dose in detail. The CT dose index and dose-length product are used to evaluate the organ dose. However, evaluations using these indicators fail to consider the age and body type of patients...
April 5, 2018: Journal of Radiation Research
Ying Tong, Yong Yin, Pinjing Cheng, Jie Lu, Tonghai Liu, Jinhu Chen, Guanzhong Gong
Cardiac activity can induce dose-volume evaluation errors for cardiac structures. The purpose of this study was to quantify the variation in dose-volume parameters for the heart, pericardium and left ventricular myocardium (LVM) throughout the cardiac circle. The heart, pericardium and LVM of 22 patients were contoured on 20 phases of electrocardiography-gated 4D computed tomography (4DCT) images acquired during breath-hold. Radiotherapy plans were designed on 0% phase of the 4DCT images, and the dose distributions of the plans were imported into MIM Maestro and deformed to each phase to generate distributions for all phases...
April 5, 2018: Journal of Radiation Research
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