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Psychosomatic Medicine

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https://www.readbyqxmd.com/read/28498279/effectiveness-of-a-stepped-collaborative-and-coordinated-health-care-network-for-somatoform-disorders-sofu-net-a-controlled-cluster-cohort-study
#1
Bernd Löwe, Katharina Piontek, Anne Daubmann, Martin Härter, Karl Wegscheider, Hans-Helmut König, Meike Shedden-Mora
OBJECTIVE: Stepped, collaborative, and coordinated approaches have been proposed as the optimal treatment strategy for somatic symptom and related disorders (SSRD), but evidence supporting this strategy is lacking. The aim of this study was to assess the effectiveness of a guideline-based health care network for patients who are at high risk of somatoform disorder (Sofu-Net). METHODS: In a controlled, prospective, observer-blinded cluster cohort study, patients who were at high risk of somatoform disorder were recruited at 18 primary care practices in the Sofu-Net and at 15 primary care practices that provided care as usual (CAU)...
May 12, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28498278/depression-and-survival-in-a-17-year-longitudinal-study-of-people-with-hiv-moderating-effects-of-race-and-education
#2
Gail Ironson, Calvin Fitch, Rick Stuetzle
OBJECTIVE: The prevalence of clinically significant depressive symptoms is 3 times higher in people living with HIV (PLWH) than in the general population. While studies have shown that depression predicts worse course with HIV, few have investigated its relationship with mortality, and none have had a 17-year follow-up period and been conducted entirely during the time since the advent of protease inhibitors. METHODS: We followed a diverse sample of HIV positive people (n=177) in the mid-range of illness for a study on stress and coping...
May 12, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28498277/influence-of-visceral-interoceptive-experience-on-the-brain-s-response-to-food-images-in-anorexia-nervosa
#3
Kara L Kerr, Scott E Moseman, Jason A Avery, Jerzy Bodurka, W Kyle Simmons
OBJECTIVE: To determine how visceral sensations affect responses to food stimuli in anorexia nervosa (AN). METHODS: Twenty weight-restored, unmedicated adolescent and young adult women with AN and twenty healthy control participants completed an interoceptive attention task during which they focused on sensations from the heart, stomach, and bladder and made ratings of these sensations. They then underwent fMRI scanning while viewing pictures of food and non-food objects...
May 12, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28498276/influence-of-uncertain-anticipation-on-brain-responses-to-aversive-rectal-distension-in-patients-with-irritable-bowel-syndrome
#4
Michiko Kano, Tomohiko Muratsubaki, Joe Morishita, Keiji Kono, Shunji Mugikura, Kei Takase, Huynh Giao Ly, Patrick Dupont, Lukas Van Oudenhove, Shin Fukudo
OBJECTIVE: We investigated if certainty and uncertainty of impending aversive visceral sensation differently modulate regional brain activity, both during anticipation and visceral sensation in irritable bowel syndrome (IBS) patients compared with healthy controls. METHODS: Twenty-six IBS patients (14 women) and 29 healthy controls (15 women) were enrolled in an fMRI study. Participants received rectal distention at an individually titrated severe discomfort level that was preceded by visual cues to induce certain (100% chance of distention), uncertain (50% chance), and safe (0% chance) anticipation...
May 12, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28498275/influence-of-acute-multi-species-and-multi-strain-probiotic-supplementation-on-cardiovascular-function-and-reactivity-to-psychological-stress-in-young-adults-a-double-blind-randomized-placebo-controlled-trial
#5
Clara M Möller, Eamon J A Olsa, Annie T Ginty, Alyssa L Rapelje, Christina L Tindall, Laura A Holesh, Karen L Petersen, Sarah M Conklin
OBJECTIVE: The potential influence of probiotic supplementation on cardiovascular health and stress responsivity remains largely unexplored. Some evidence suggests the possibility that probiotics may influence blood pressure. A separate body of research suggests that exaggerated cardiovascular reactions to acute psychological stress in the laboratory predict cardiovascular morbidity and mortality. The current investigation explored the effect of acute probiotic use on: 1) resting cardiovascular measures in healthy young adults and 2) cardiovascular and psychological reactions to an acute psychological stressor in the laboratory...
May 12, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28498274/fornix-structural-connectivity-and-allostatic-load-empirical-evidence-from-schizophrenia-patients-and-healthy-controls
#6
Anya Savransky, Joshua Chiappelli, Laura M Rowland, Krista Wisner, Dinesh K Shukla, Peter Kochunov, L Elliot Hong
OBJECTIVE: The fornix is a white matter tract carrying the fibers connecting the hippocampus and the hypothalamus, two essential stress-regulatory structures of the brain. We tested the hypothesis that allostatic load (AL), derived from a battery of peripheral biomarkers indexing the cumulative effects of stress, is associated with abnormalities in brain white matter microstructure, especially the fornix; and that higher AL may help explain the white matter abnormalities in schizophrenia...
May 12, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28498273/effects-of-preoperative-psychological-interventions-on-catecholamineand-cortisol-levels-after-surgery-in-coronary-artery-bypass-graft-patients-the-randomized-controlled-psy-heart-trial
#7
Stefan Salzmann, Frank Euteneuer, Johannes A C Laferton, Charlotte J Auer, Meike C Shedden-Mora, Manfred Schedlowski, Rainer Moosdorf, Winfried Rief
OBJECTIVE: To examine whether preoperative psychological interventions targeting patients' expectations are capable of influencing the biological stress response after coronary artery bypass graft (CABG) surgery and could thus improve recovery after heart surgery. METHODS: Randomized controlled trial with assessments 10 days before surgery, post-psychological intervention (day of hospital admission, but before surgery), postoperative (6-8 days later) and at follow-up (6 months after surgery)...
May 12, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28481761/the-impact-of-narrative-expressive-writing-on-heart-rate-heart-rate-variability-and-blood-pressure-following-marital-separation
#8
Kyle J Bourassa, John J B Allen, Matthias R Mehl, David A Sbarra
OBJECTIVE: Divorce is a common stressor that is associated with increased risk for poor long-term physical and mental health. Using an experimental design, the current study examined the impact of expressive writing (EW) on average heart rate (HR), heart rate variability (HRV), and blood pressure (BP) 7.5 months later. METHODS: Participants from a community sample of recently separated adults (N=109) were assigned to one of three conditions, traditional EW, narrative EW, or a control writing condition, and assessed three times over an average of 7...
May 5, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28452825/joint-impact-of-early-life-adversity-and-comt-val158met-rs4680-genotypes-on-the-adult-cortisol-response-to-psychological-stress
#9
William R Lovallo, Mary-Anne Enoch, Kristen H Sorocco, Andrea S Vincent, Ashley Acheson, Andrew J Cohoon, Colin A Hodgkinson, David Goldman
OBJECTIVE: Exposure to stress during critical periods of development can diminish stress reactivity by the hypothalamic-pituitary-adrenocortical axis. Genetic characteristics may further modify this effect of early adversity, leading to a gene-by-environment (G x E) interaction on stress reactivity in adulthood. Val-allele carriers of a common polymorphism of the COMT gene (Val158Met, rs4680) have rapid removal of catecholamines in the prefrontal cortex, limbic system, and reward centers...
April 27, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28445210/perceived-discrimination-and-longitudinal-change-in-kidney-function-among-urban-adults
#10
May A Beydoun, Angedith Poggi-Burke, Alan B Zonderman, Ola S Rostant, Michele K Evans, Deidra C Crews
OBJECTIVE: Perceived discrimination has been associated with psychosocial distress and adverse health outcomes. We examined associations of perceived discrimination measures with changes in kidney function in a prospective cohort study, the Healthy Aging in Neighborhoods of Diversity Across the LifeSpan. METHODS: Our study included 1,620 participants with preserved baseline kidney function (estimated glomerular filtration rate (eGFR) ≥60 ml/min/1.73m) (662 Whites and 958 African-Americans (AA), aged 30-64 years)...
April 26, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28445209/intelligence-and-interleukin-6-in-older-adults-the-role-of-repetitive-thought
#11
Suzanne C Segerstrom, Rebecca G Reed, April B Scott
OBJECTIVE: Higher IQ correlates with lower systemic inflammation, consistent with an association between lower IQ and disease risk. The present study examined the role of repetitive thought (RT) in the relationship between IQ and interleukin (IL)-6. RT is thinking attentively, repeatedly, and frequently about oneself and one's world and is characterized by Valence (positive-negative), Purpose (searching-solving), and Total quantity (much-little). METHODS: Estimated IQ and RT dimension scores were assessed at baseline in a sample of older adults (N=120, Mage=74 years), who thereafter had blood drawn up to 10 times semiannually (n=799)...
April 26, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28437381/mean-levels-and-variability-in-affect-diabetes-self-care-behaviors-and-continuously-monitored-glucose-a-daily-study-of-latinos-with-type-2-diabetes
#12
Julie Wagner, Stephen Armeli, Howard Tennen, Angela Bermudez-Millan, Howard Wolpert, Rafael Pérez-Escamilla
OBJECTIVE: This study investigated between-person and within-person associations among mean levels and variability in affect, diabetes self-care behaviors, and continuously monitored glucose in Latinos with type 2 diabetes. METHODS: Fifty participants (mean age=57.8 [SD=11.7] years, 74% women, mean A1c=8.3% [SD=1.5%]) wore a 'blinded' continuous glucose monitor for 7 days, and they responded to twice-daily automated phone surveys regarding positive affect (PA), negative affect (NA) and self-care behaviors...
April 21, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28437380/lifestyle-and-neurocognition-in-older-adults-with-cardiovascular-risk-factors-and-cognitive-impairment
#13
James A Blumenthal, Patrick J Smith, Stephanie Mabe, Alan Hinderliter, Kathleen Welsh-Bohmer, Jeffrey N Browndyke, Pao-Hwa Lin, William Kraus, P Murali Doraiswamy, James Burke, Andrew Sherwood
OBJECTIVE: To determine the relationship of lifestyle factors and neurocognitive functioning in older adults with vascular risk factors and cognitive impairment, without dementia (CIND). METHODS: One hundred sixty adults (Mean = 65.4±6.8 years) with CIND completed neurocognitive assessments of executive function, processing speed, and memory. Objective measures of physical activity using accelerometry, aerobic capacity determined by exercise testing, and dietary habits quantified by the Food Frequency Questionnaire and 4-Day Food Diary to assess adherence to the Mediterranean and DASH diets were obtained to assess direct effects with neurocognition...
April 21, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28437379/associations-of-lifetime-trauma-and-chronic-stress-with-c-reactive-protein-in-adults-ages-50-and-older-examining-the-moderating-role-of-perceived-control
#14
Ari J Elliot, Christopher J Mooney, Frank J Infurna, Benjamin P Chapman
OBJECTIVE: To investigate whether high perceived control mitigates systemic inflammatory risk associated with traumatic and chronic stress exposures in older adults. METHODS: A sample of community-dwelling adults ages 50 and older (N=4,779) was drawn from the Health and Retirement Study (HRS). Structural equation models tested interactions of lifetime trauma and chronic stress with mastery and perceived constraints predicting baseline levels and four-year change in C-reactive protein (CRP)...
April 21, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28422780/understanding-the-gut-microbiota-in-inflammatory-and-functional-gastrointestinal-diseases
#15
Johanna Sundin, Lena Öhman, Magnus Simren
OBJECTIVE: During the last decade experimental and observational studies have shown that patients with Inflammatory Bowel Disease (IBD) and Irritable Bowel Syndrome (IBS) may have an altered intestinal microbial composition compared to healthy subjects. However, no uniform microbial signature has as yet been detected for either IBD or IBS. This review summarizes the current knowledge of microbial dysbiosis, and its potential relationship to the pathophysiology in IBD and IBS. METHODS: A selective review was conducted to summarize the current knowledge of gut microbiota in the pathophysiology of IBD and IBS...
April 18, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28406804/subjective-general-health-and-the-social-regulation-of-hypothalamic-activity
#16
Casey L Brown, Lane Beckes, Joseph P Allen, James A Coan
OBJECTIVE: Social support is associated with better health. This association may be partly mediated through the social regulation of adrenomedullary activity related to poor cardiovascular health and glucocorticoid activity known to inhibit immune functioning. These physiological cascades originate in the hypothalamic areas that are involved in the neural response to threat. We investigated whether the down regulation, by social support, of hypothalamic responses to threat is associated with better subjective health...
April 12, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28406803/investigating-clinical-benefits-of-a-novel-sleep-focused-mind-body-program-on-gulf-war-illness-gwi-symptoms-a-randomized-controlled-trial
#17
Yoshio Nakamura, David L Lipschitz, Gary W Donaldson, Yuri Kida, Samuel Williams, Richard Landward, Don Glover, Gavin West, Ashok Tuteja
OBJECTIVE: Mind-Body Bridging (MBB) has been shown to be effective for improving disturbed sleep. In this prospective randomized-controlled trial, we evaluated the efficacy of sleep-focused MBB compared with sleep education control (SED) for improving sleep in previously deployed Gulf War Veterans. METHODS: US military service members with sleep and physical health complaints who were deployed in 1990-1991 were randomized to receive MBB (n=33) or SED (n=27) between 2012 and 2015, each comprised three weekly sessions...
April 12, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28323668/mindfulness-meditation-training-and-executive-control-network-resting-state-functional-connectivity-a-randomized-controlled-trial
#18
Adrienne A Taren, Peter J Gianaros, Carol M Greco, Emily K Lindsay, April Fairgrieve, Kirk Warren Brown, Rhonda K Rosen, Jennifer L Ferris, Erica Julson, Anna L Marsland, J David Creswell
OBJECTIVE: Mindfulness meditation training has been previously shown to enhance behavioral measures of executive control (e.g. attention, working memory, cognitive control), but the neural mechanisms underlying these improvements are largely unknown. Here, we test whether mindfulness training interventions foster executive control by strengthening functional connections between dorsolateral prefrontal cortex (dlPFC) - a hub of the executive control network - and frontoparietal regions that coordinate executive function...
March 20, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28319558/effects-of-medical-interventions-on-gender-dysphoria-and-body-image-a-follow-up-study
#19
Tim C van de Grift, Els Elaut, Susanne C Cerwenka, Peggy T Cohen-Kettenis, Griet De Cuypere, Hertha Richter-Appelt, Baudewijntje P C Kreukels
OBJECTIVES: The aim of the European Network for the Investigation of Gender Incongruence is to investigate the status of all individuals who had applied for gender confirming interventions from 2007 until 2009, irrespective of whether they received treatment. The current article describes the study protocol, the effect of medical treatment on gender dysphoria and body image, and the predictive value of (pre)treatment factors on post-treatment outcomes. METHODS: Data were collected on medical interventions, transition status, gender dysphoria (Utrecht Gender Dysphoria Scale), and body image (Body Image Scale for Transsexuals)...
March 18, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28306624/the-association-of-work-characteristics-with-ovarian-cancer-risk-and-mortality
#20
Claudia Trudel-Fitzgerald, Elizabeth M Poole, Annika Idahl, Eva Lundin, Anil K Sood, Ichiro Kawachi, Laura D Kubzansky, Shelley S Tworoger
OBJECTIVE: Ovarian cancer (OvCA) is a leading cause of cancer death for women. Depression and social isolation have been associated with a higher OvCA risk and poorer survival, but other forms of chronic psychosocial stress, including work-related characteristics, remain understudied. METHODS: Women from three prospective cohorts (Nurses' Health Study (NHS), n=31,754; Nurses' Health Study II (NHSII), n=74,260; Northern Sweden Health and Disease Study (NSHDS); nnested case-control study=196) completed a job questionnaire, assessing demand and control at work, social support provided by coworkers and supervisor, and job security...
March 17, 2017: Psychosomatic Medicine
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