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Psychosomatic Medicine

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https://www.readbyqxmd.com/read/28604559/wellbeing-and-arthritis-incidence-the-role-of-inflammatory-mechanisms-findings-from-the-english-longitudinal-study-of-ageing
#1
Judith A Okely, Alexander Weiss, Catharine R Gale
OBJECTIVE: Higher wellbeing is associated with lower levels of inflammatory markers in healthy populations; however, it is unclear whether this association translates into a reduced risk of disease. In the current study, we tested whether the association between wellbeing and inflammation results in a lower risk of arthritis. METHODS: The sample consisted of 5,622 participants aged ≥ 50 from the English Longitudinal Study of Ageing and included 6 waves of data collection...
June 10, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28604560/childhood-cognitive-ability-and-age-related-changes-in-physical-capability-from-midlife-findings-from-a-british-birth-cohort-study
#2
Rachel Cooper, Marcus Richards, Diana Kuh
OBJECTIVE: To test the hypothesis that higher childhood cognitive ability is associated with reduced risk of decline in physical capability in late midlife. METHODS: Participants were 1954 men and women from the MRC National Survey of Health and Development with complete data on cognitive ability at age 15 and measures of grip strength and chair rise speed at ages 53 and 60-64 years. Using multinomial logistic regression, associations of childhood cognitive ability with categories of change in grip strength and chair rise speed (i...
June 9, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28640179/engagement-in-pleasant-leisure-activities-and-blood-pressure-a-5-year-longitudinal-study-in-alzheimer-s-caregivers
#3
Brent T Mausbach, Rosa Romero-Moreno, Taylor Bos, Roland von Känel, Michael G Ziegler, Matthew A Allison, Paul J Mills, Joel E Dimsdale, Sonia Ancoli-Israel, Andrés Losada, María Márquez-González, Thomas L Patterson, Igor Grant
OBJECTIVE: Elevated blood pressure is a significant public health concern, particularly given its association with cardiovascular disease risk, including stroke. Caring for a loved one with Alzheimer's disease has been associated with physical health morbidity, including higher blood pressure. Engagement in adaptive coping strategies may help prevent blood pressure elevation in this population. This 5-year longitudinal study examined whether greater participation in pleasant leisure activities was associated with reduced blood pressure in caregivers...
May 31, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28570439/cortisol-awakening-response-as-a-prospective-risk-factor-for-depressive-symptoms-in-women-after-treatment-for-breast-cancer
#4
Kate Ryan Kuhlman, Michael R Irwin, Patricia A Ganz, Catherine M Crespi, Laura Petersen, Arash Asher, Julienne E Bower
OBJECTIVE: To investigate hypothalamic-pituitary-adrenal axis (HPA-axis) functioning as a neurobiological risk factor for depressive symptoms in an ongoing longitudinal, observational study of women undergoing treatment and recovery from breast cancer. Many women with breast cancer experience depressive symptoms that interfere with their treatment, recovery, and quality of life. Psychosocial risk factors for depression among cancer patients and survivors have been identified, yet neurobiological risk factors in this population remain largely unexamined...
May 31, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28570437/identification-and-validation-of-clinically-relevant-clusters-of-severe-fatigue-in-rheumatoid-arthritis
#5
Neil Basu, Gareth T Jones, Gary J Macfarlane, Katie L Druce
OBJECTIVE: The considerable heterogeneity of rheumatoid arthritis (RA) related fatigue is the greatest challenge to determining pathogenesis. The identification of homogenous sub-types of severe fatigue would inform the design and analysis of experiments seeking to characterise the likely numerous causal pathways which underpin the symptom. This study aimed to identify and validate such fatigue sub-types in patients with RA. METHODS: Data were obtained from patients recruited to the British Society for Rheumatology Biologics register for RA, as either receiving traditional Disease Modifying Anti-Rheumatic Drugs (DMARD cohort, n=522) or commencing anti-TNF therapy (anti-TNF cohort, n=3909)...
May 31, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28570438/surgically-induced-changes-in-gut-microbiome-and-hedonic-eating-as-related-to-weight-loss-preliminary-findings-in-obese-women-undergoing-bariatric-surgery
#6
Claudia P Sanmiguel, Jonathan Jacobs, Arpana Gupta, Tiffany Ju, Jean Stains, Kristen Coveleskie, Venu Lagishetty, Anna Balioukova, Yijun Chen, Erik Dutson, Emeran Mayer, Jennifer S Labus
OBJECTIVE: Weight-loss surgery results in significant changes in the anatomy, function and intraluminal environment of the gastrointestinal tract affecting the gut microbiome. While bariatric surgery results in sustained weight loss, decreased appetite and hedonic eating; it is unknown if the surgery-induced alterations in gut microbiota play a role in the observed changes in hedonic eating. We explored the following hypotheses 1) Laparoscopic sleeve gastrectomy results in changes in gut microbial composition ; 2) Alterations in gut microbiota are related to weight loss; 3) Alterations in gut microbiome are associated with changes in appetite and hedonic eating...
May 30, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28557822/gut-microbiota-and-the-gut-brain-axis-new-insights-in-the-pathophysiology-of-metabolic-syndrome
#7
Nicolien de Clercq, Myrthe N Frissen, Albert K Groen, Max Nieuwdorp
OBJECTIVE: Emerging pre-clinical evidence has shown that the bidirectional signaling between the gastrointestinal tract and the brain, the so-called gut-brain axis, plays an important role in both host metabolism and behavior. In this review, we will discuss the potential mechanisms of the brain-gut axis in relation to the pathophysiology of metabolic syndrome. METHODS: A selective literature review was conducted to evaluate gastrointestinal and brain interactions...
May 27, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28557821/non-completion-of-nighttime-ambulatory-blood-pressure-monitoring-potential-for-selection-bias-in-analyses-of-non-dipping
#8
Kevin J Sundquist, Joseph E Schwartz, Donald Edmondson, Jennifer A Sumner
No abstract text is available yet for this article.
May 27, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28557820/features-of-resting-state-eeg-theta-coherence-in-somatic-symptom-disorder-compared-to-major-depressive-disorder-a-pilot-study
#9
Jaeyoung Ahn, Doug Hyun Han, Ji Sun Hong, Kyoung Joon Min, Young Sik Lee, Bong-Jin Hahm, Sun Mi Kim
OBJECTIVE: Somatic symptom disorder (SSD) often co-occurs with major depressive disorder (MDD). Both conditions share common psychobiological and biobehavioral characteristics, but little is known about differential patterns in brain function. In this study, we compared resting-state functional brain connectivity between SSD and MDD using quantitative electroencephalography (QEEG). METHODS: Fifteen patients with SSD (SSD group), 15 patients with MDD (MDD group), and 15 healthy volunteers (HC group) participated in this study...
May 27, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28498279/effectiveness-of-a-stepped-collaborative-and-coordinated-health-care-network-for-somatoform-disorders-sofu-net-a-controlled-cluster-cohort-study
#10
Bernd Löwe, Katharina Piontek, Anne Daubmann, Martin Härter, Karl Wegscheider, Hans-Helmut König, Meike Shedden-Mora
OBJECTIVE: Stepped, collaborative, and coordinated approaches have been proposed as the optimal treatment strategy for somatic symptom and related disorders (SSRD), but evidence supporting this strategy is lacking. The aim of this study was to assess the effectiveness of a guideline-based health care network for patients who are at high risk of somatoform disorder (Sofu-Net). METHODS: In a controlled, prospective, observer-blinded cluster cohort study, patients who were at high risk of somatoform disorder were recruited at 18 primary care practices in the Sofu-Net and at 15 primary care practices that provided care as usual (CAU)...
May 12, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28498278/depression-and-survival-in-a-17-year-longitudinal-study-of-people-with-hiv-moderating-effects-of-race-and-education
#11
Gail Ironson, Calvin Fitch, Rick Stuetzle
OBJECTIVE: The prevalence of clinically significant depressive symptoms is 3 times higher in people living with HIV (PLWH) than in the general population. While studies have shown that depression predicts worse course with HIV, few have investigated its relationship with mortality, and none have had a 17-year follow-up period and been conducted entirely during the time since the advent of protease inhibitors. METHODS: We followed a diverse sample of HIV positive people (n=177) in the mid-range of illness for a study on stress and coping...
May 12, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28498277/influence-of-visceral-interoceptive-experience-on-the-brain-s-response-to-food-images-in-anorexia-nervosa
#12
Kara L Kerr, Scott E Moseman, Jason A Avery, Jerzy Bodurka, W Kyle Simmons
OBJECTIVE: To determine how visceral sensations affect responses to food stimuli in anorexia nervosa (AN). METHODS: Twenty weight-restored, unmedicated adolescent and young adult women with AN and twenty healthy control participants completed an interoceptive attention task during which they focused on sensations from the heart, stomach, and bladder and made ratings of these sensations. They then underwent fMRI scanning while viewing pictures of food and non-food objects...
May 12, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28498276/influence-of-uncertain-anticipation-on-brain-responses-to-aversive-rectal-distension-in-patients-with-irritable-bowel-syndrome
#13
Michiko Kano, Tomohiko Muratsubaki, Joe Morishita, Keiji Kono, Shunji Mugikura, Kei Takase, Huynh Giao Ly, Patrick Dupont, Lukas Van Oudenhove, Shin Fukudo
OBJECTIVE: We investigated if certainty and uncertainty of impending aversive visceral sensation differently modulate regional brain activity, both during anticipation and visceral sensation in irritable bowel syndrome (IBS) patients compared with healthy controls. METHODS: Twenty-six IBS patients (14 women) and 29 healthy controls (15 women) were enrolled in an fMRI study. Participants received rectal distention at an individually titrated severe discomfort level that was preceded by visual cues to induce certain (100% chance of distention), uncertain (50% chance), and safe (0% chance) anticipation...
May 12, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28498275/influence-of-acute-multi-species-and-multi-strain-probiotic-supplementation-on-cardiovascular-function-and-reactivity-to-psychological-stress-in-young-adults-a-double-blind-randomized-placebo-controlled-trial
#14
Clara M Möller, Eamon J A Olsa, Annie T Ginty, Alyssa L Rapelje, Christina L Tindall, Laura A Holesh, Karen L Petersen, Sarah M Conklin
OBJECTIVE: The potential influence of probiotic supplementation on cardiovascular health and stress responsivity remains largely unexplored. Some evidence suggests the possibility that probiotics may influence blood pressure. A separate body of research suggests that exaggerated cardiovascular reactions to acute psychological stress in the laboratory predict cardiovascular morbidity and mortality. The current investigation explored the effect of acute probiotic use on: 1) resting cardiovascular measures in healthy young adults and 2) cardiovascular and psychological reactions to an acute psychological stressor in the laboratory...
May 12, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28498274/fornix-structural-connectivity-and-allostatic-load-empirical-evidence-from-schizophrenia-patients-and-healthy-controls
#15
Anya Savransky, Joshua Chiappelli, Laura M Rowland, Krista Wisner, Dinesh K Shukla, Peter Kochunov, L Elliot Hong
OBJECTIVE: The fornix is a white matter tract carrying the fibers connecting the hippocampus and the hypothalamus, two essential stress-regulatory structures of the brain. We tested the hypothesis that allostatic load (AL), derived from a battery of peripheral biomarkers indexing the cumulative effects of stress, is associated with abnormalities in brain white matter microstructure, especially the fornix; and that higher AL may help explain the white matter abnormalities in schizophrenia...
May 12, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28498273/effects-of-preoperative-psychological-interventions-on-catecholamineand-cortisol-levels-after-surgery-in-coronary-artery-bypass-graft-patients-the-randomized-controlled-psy-heart-trial
#16
Stefan Salzmann, Frank Euteneuer, Johannes A C Laferton, Charlotte J Auer, Meike C Shedden-Mora, Manfred Schedlowski, Rainer Moosdorf, Winfried Rief
OBJECTIVE: To examine whether preoperative psychological interventions targeting patients' expectations are capable of influencing the biological stress response after coronary artery bypass graft (CABG) surgery and could thus improve recovery after heart surgery. METHODS: Randomized controlled trial with assessments 10 days before surgery, post-psychological intervention (day of hospital admission, but before surgery), postoperative (6-8 days later) and at follow-up (6 months after surgery)...
May 12, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28481761/the-impact-of-narrative-expressive-writing-on-heart-rate-heart-rate-variability-and-blood-pressure-following-marital-separation
#17
Kyle J Bourassa, John J B Allen, Matthias R Mehl, David A Sbarra
OBJECTIVE: Divorce is a common stressor that is associated with increased risk for poor long-term physical and mental health. Using an experimental design, the current study examined the impact of expressive writing (EW) on average heart rate (HR), heart rate variability (HRV), and blood pressure (BP) 7.5 months later. METHODS: Participants from a community sample of recently separated adults (N=109) were assigned to one of three conditions, traditional EW, narrative EW, or a control writing condition, and assessed three times over an average of 7...
May 5, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28452825/joint-impact-of-early-life-adversity-and-comt-val158met-rs4680-genotypes-on-the-adult-cortisol-response-to-psychological-stress
#18
William R Lovallo, Mary-Anne Enoch, Kristen H Sorocco, Andrea S Vincent, Ashley Acheson, Andrew J Cohoon, Colin A Hodgkinson, David Goldman
OBJECTIVE: Exposure to stress during critical periods of development can diminish stress reactivity by the hypothalamic-pituitary-adrenocortical axis. Genetic characteristics may further modify this effect of early adversity, leading to a gene-by-environment (G x E) interaction on stress reactivity in adulthood. Val-allele carriers of a common polymorphism of the COMT gene (Val158Met, rs4680) have rapid removal of catecholamines in the prefrontal cortex, limbic system, and reward centers...
April 27, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28445210/perceived-discrimination-and-longitudinal-change-in-kidney-function-among-urban-adults
#19
May A Beydoun, Angedith Poggi-Burke, Alan B Zonderman, Ola S Rostant, Michele K Evans, Deidra C Crews
OBJECTIVE: Perceived discrimination has been associated with psychosocial distress and adverse health outcomes. We examined associations of perceived discrimination measures with changes in kidney function in a prospective cohort study, the Healthy Aging in Neighborhoods of Diversity Across the LifeSpan. METHODS: Our study included 1,620 participants with preserved baseline kidney function (estimated glomerular filtration rate (eGFR) ≥60 ml/min/1.73m) (662 Whites and 958 African-Americans (AA), aged 30-64 years)...
April 26, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28445209/intelligence-and-interleukin-6-in-older-adults-the-role-of-repetitive-thought
#20
Suzanne C Segerstrom, Rebecca G Reed, April B Scott
OBJECTIVE: Higher IQ correlates with lower systemic inflammation, consistent with an association between lower IQ and disease risk. The present study examined the role of repetitive thought (RT) in the relationship between IQ and interleukin (IL)-6. RT is thinking attentively, repeatedly, and frequently about oneself and one's world and is characterized by Valence (positive-negative), Purpose (searching-solving), and Total quantity (much-little). METHODS: Estimated IQ and RT dimension scores were assessed at baseline in a sample of older adults (N=120, Mage=74 years), who thereafter had blood drawn up to 10 times semiannually (n=799)...
April 26, 2017: Psychosomatic Medicine
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