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Progress in Cardiovascular Diseases

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https://www.readbyqxmd.com/read/28801124/changing-our-approach-to-stage-d-heart-failure
#1
REVIEW
Miriam Becnel, Hector O Ventura, Selim R Krim
Despite the tremendous progress made in the management of heart failure (HF), many patients reach advanced stages. This paper aims to present a practical approach to the stage D HF patient who is no longer responding to optimal medical therapy. We discuss all available therapies for this patient population. We also offer some important caveats with regard to identification, risk stratification, evaluation and treatment including early patient referral to a center with an advanced HF program. Given the changing landscape of heart transplantation and an impending change in the allocation system, we also intend to engage a discussion on the need for a paradigm shift towards left ventricular assist device therapy in this population...
August 8, 2017: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/28782529/from-heart-failure-to-journal-metrics-making-progress-in-cardiovascular-diseases
#2
EDITORIAL
Carl J Lavie
No abstract text is available yet for this article.
August 3, 2017: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/28779953/comprehensive-heart-failure-management
#3
EDITORIAL
Hector O Ventura, Ileana L Piña
No abstract text is available yet for this article.
August 2, 2017: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/28743529/implementation-of-a-patient-navigator-program-to-reduce-30-day-heart-failure-readmission-rate
#4
REVIEW
Katherine E Di Palo, Khusbu Patel, Manaf Assafin, Ileana L Piña
With increasing awareness to provide personalized care our institution applied the American College of Cardiology (ACC) Patient Navigator Program to identify hospitalized heart failure (HF) patients and improve transitions and outcomes. Utilizing a Navigator Team (NT) composed of a nurse and clinical pharmacist, we delivered evidenced-based interventions and hypothesized this approach would improve identification of HF inpatients and reduce the 30-day all-cause readmission rate. Patients were followed from admission to discharge and received at least one intervention, tailored to the patient's health literacy and social needs...
July 22, 2017: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/28733079/is-an-admission-for-decompensated-heart-failure-inevitable
#5
REVIEW
Alexander J Blood, Ariane M Fraiche, Zubin J Eapen
Given the high prevalence of heart failure (HF) and the profound impact on morbid, mortality, and health care costs, strategies to improve outcomes and reduce cost have become progressively more attractive. Reducing HF hospitalizations as a study outcome has gained traction in recent years. The basic hypothesis of these investigations is that HF hospitalizations are preventable and harmful. This article examines advancements in pharmacotherapy, medical devices, and health care delivery techniques targeting reductions in HF hospitalizations and evaluates the role and implications of hospitalization in the natural history of HF...
July 18, 2017: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/28793972/taking-physical-activity-exercise-and-fitness-to-a-higher-level
#6
EDITORIAL
Ulrik Wisloff, Carl J Lavie
No abstract text is available yet for this article.
June 2017: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/28689854/impact-of-cardiac-rehabilitation-and-exercise-training-programs-in-coronary-heart-disease
#7
REVIEW
Sergey Kachur, Vasutakarn Chongthammakun, Carl J Lavie, Alban De Schutter, Ross Arena, Richard V Milani, Barry A Franklin
Cardiovascular rehabilitation (CR) is the process of developing and maintaining an optimal level of physical, social, and psychological well-being in order to promote recovery from cardiovascular (CV) illness. It is a multi-disciplinary approach encompassing supervised exercise training, patient counseling, education and nutritional guidance that may also enhance quality of life. Beneficial CV effects may include improving coronary heart disease risk factors; particularly exercise capacity, reversing cardiac remodeling, and favorably modifying metabolism and systemic oxygen transport...
June 2017: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/28684221/exercise-training-for-prevention-and-treatment-of-heart-failure
#8
REVIEW
Nitin Kondamudi, Mark Haykowsky, Daniel E Forman, Jarett D Berry, Ambarish Pandey
Heart failure (HF) results in high healthcare costs and burdens for the United States in respects to hospitalizations, therapies, and associated disability. The relative proportion of HF with preserved ejection fraction (HFpEF) compared with HF with reduced ejection fraction (HFrEF) is on the rise; HFpEF has already become the dominant form of HF and it continues to increase. The serious implications of these trends are compounded by a dearth of effective HFpEF therapies. While low physical activity, low cardiorespiratory fitness (CRF), and obesity, are risk factors for HF in general, they particularly predispose to HFpEF...
June 2017: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/28666746/micrornas-as-important-regulators-of-exercise-adaptation
#9
REVIEW
Gustavo J J Silva, Anja Bye, Hamid El Azzouzi, Ulrik Wisløff
A significant body of evidence supports the protective role of exercise training (ET) in cardiovascular diseases, skeletal muscle dystrophies, several types of cancer, Alzheimer disease or even in the recovery of spinal cord injury. In spite of this, the molecular mechanisms underlying the beneficial effects of exercise training are not well understood and remain elusive. Several mechanisms have been proposed in the past, but more recently microRNAs (miRNAs), small non-coding RNA molecules involved in a variety of basic biological processes that negatively modulate gene expression, recognized as important regulatory molecules...
June 2017: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/28606473/cardiorespiratory-fitness-and-exercise-training-in-african-americans
#10
REVIEW
Damon L Swift, Neil M Johannsen, Conrad P Earnest, Robert L Newton, Joshua E McGee, Timothy S Church
African Americans (AAs) have a higher risk for cardiovascular disease (CVD) compared to their Caucasian American (CA) counterparts, which represents a major health disparity. Low cardiorespiratory fitness (CRF) is a well-established independent risk factor for all-cause and CVD mortality, which has been shown across many epidemiological and clinical trials to be lower in AAs compared to CAs. While much attention has been given to traditional health disparity risk factors (e.g. blood pressure, obesity, insulin resistance), the impact of racial differences in CRF on CVD mortality has not been widely considered...
June 2017: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/28576674/public-park-spaces-as-a-platform-to-promote-healthy-living-introducing-a-healthpark-concept
#11
REVIEW
Ross Arena, Samantha Bond, Robert O'Neill, Deepika R Laddu, Andrew P Hills, Carl J Lavie, Amy McNeil
The concept of Healthy Living (HL) as a primary medical intervention continues to gain traction, and rightfully so. Being physically active, consuming a nutritious diet, not smoking and maintaining an appropriate body weight constitute the HL polypill, the foundation of HL medicine (HLM). Daily use of the HL polypill, working toward optimal dosages, portends profound health benefits, substantially reducing the risk of chronic disease [i.e., cardiovascular disease (CVD), pulmonary disease, metabolic syndromes, certain cancers, etc...
June 2017: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/28502849/the-interaction-of-cardiorespiratory-fitness-with-obesity-and-the-obesity-paradox-in-cardiovascular-disease
#12
REVIEW
Ahmet Afşin Oktay, Carl J Lavie, Peter F Kokkinos, Parham Parto, Ambarish Pandey, Hector O Ventura
Overweight and obesity are well-established risk factors for most cardiovascular diseases (CVD), including coronary heart disease (CHD), heart failure (HF), and atrial fibrillation. Despite the strong link between excess adiposity and risk of CVD, growing evidence has demonstrated an obesity paradox in patients with CVD. This phenomenon is characterized by a better prognosis in overweight and mildly obese CVD patients than their leaner counterparts. Moreover, the worst outcomes are often incurred by underweight CVD patients, followed by those of normal weight or severely obese...
June 2017: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/28502848/exercise-training-in-athletes-with-heart-disease
#13
REVIEW
Antonio B Fernandez, Paul D Thompson
Exercise events and sport participation have increased over recent decades. The average age of sports participants has also increased with a potential parallel increase in the number of exercise participants with both occult and diagnosed cardiovascular disease (CVD). Habitual physical activity and exercise training reduce atherosclerotic CVD (ASCVD) risk in a curvilinear fashion by affecting multiple ASCVD risk factors. Nonetheless, exercise also increases the risk of sudden cardiac death in both young and adult individuals with occult CVD making it important to balance the risks and benefits of exercise and exercise training in these individuals...
June 2017: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/28385556/high-intensity-interval-training-for-maximizing-health-outcomes
#14
REVIEW
Trine Karlsen, Inger-Lise Aamot, Mark Haykowsky, Øivind Rognmo
Regular physical activity and exercise training are important actions to improve cardiorespiratory fitness and maintain health throughout life. There is solid evidence that exercise is an effective preventative strategy against at least 25 medical conditions, including cardiovascular disease, stroke, hypertension, colon and breast cancer, and type 2 diabetes. Traditionally, endurance exercise training (ET) to improve health related outcomes has consisted of low- to moderate ET intensity. However, a growing body of evidence suggests that higher exercise intensities may be superior to moderate intensity for maximizing health outcomes...
June 2017: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/28377168/a-reference-equation-for-normal-standards-for-vo2-max-analysis-from-the-fitness-registry-and-the-importance-of-exercise-national-database-friend-registry
#15
REVIEW
Jonathan Myers, Leonard A Kaminsky, Ricardo Lima, Jeffrey W Christle, Euan Ashley, Ross Arena
Existing normal standards for maximal oxygen uptake (VO2 max) are problematic because they tend to be population specific, lack normal distribution and portability, and are poorly represented by women. The objective of the current study was to apply the Fitness Registry and the Importance of Exercise: A National Data Base (FRIEND) Registry to improve upon previous regression formulas for normal standards for VO2 max using treadmill testing. Maximal treadmill tests were performed in 7783 healthy men and women (20-79years; maximal RER >1...
June 2017: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/28365296/running-as-a-key-lifestyle-medicine-for-longevity
#16
REVIEW
Duck-Chul Lee, Angelique G Brellenthin, Paul D Thompson, Xuemei Sui, I-Min Lee, Carl J Lavie
Running is a popular and convenient leisure-time physical activity (PA) with a significant impact on longevity. In general, runners have a 25%-40% reduced risk of premature mortality and live approximately 3 years longer than non-runners. Recently, specific questions have emerged regarding the extent of the health benefits of running versus other types of PA, and perhaps more critically, whether there are diminishing returns on health and mortality outcomes with higher amounts of running. This review details the findings surrounding the impact of running on various health outcomes and premature mortality, highlights plausible underlying mechanisms linking running with chronic disease prevention and longevity, identifies the estimated additional life expectancy among runners and other active individuals, and discusses whether there is adequate evidence to suggest that longevity benefits are attenuated with higher doses of running...
June 2017: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/28286137/impact-of-cardiorespiratory-fitness-on-all-cause-and-disease-specific-mortality-advances-since-2009
#17
REVIEW
Matthew P Harber, Leonard A Kaminsky, Ross Arena, Steven N Blair, Barry A Franklin, Jonathan Myers, Robert Ross
Cardiorespiratory fitness (CRF) has been one of the most widely examined physiological variables, particularly as it relates to functional capacity and human performance. Over the past three decades, CRF has emerged as a strong, independent predictor of all-cause and disease-specific mortality. The evidence supporting the prognostic use of CRF is so powerful that the American Heart Association recently advocated for the routine assessment of CRF as a clinical vital sign. Interestingly, the continuity of evidence of the inverse relationship between CRF and mortality over the past decade exists despite a wide variation of methods used to assess CRF in these studies, ranging from the gold-standard method of directly measured maximal oxygen uptake (VO2max) during cardiopulmonary exercise testing to estimation from exercise tests and non-exercise prediction equations...
June 2017: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/28274819/impact-of-changes-in-cardiorespiratory-fitness-on-hypertension-dyslipidemia-and-survival-an-overview-of-the-epidemiological-evidence
#18
REVIEW
Xuemei Sui, Mark A Sarzynski, Duck-Chul Lee, Peter F Kokkinos
Over the last fifty years, cardiorespiratory fitness (CRF) has been firmly established as an important risk factor for cardiovascular disease (CVD) and all-cause mortality. Mounting evidence supports a strong and inverse association between baseline CRF and the risk of developing hypertension (HTN) and dyslipidemia. Accumulating evidence also suggests that improving or maintaining a certain level of CRF over time leads to lower incidence of HTN and dyslipidemia and improves survival. These findings are promising, with significant public health importance, and warrant further evaluation to elucidate the role of longitudinal changes in CRF during the lifespan on CVD morbidity and mortality, as well as all-cause survival...
June 2017: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/28274818/personal-activity-intelligence-pai-sedentary-behavior-and-cardiovascular-risk-factor-clustering-the-hunt-study
#19
REVIEW
Nina Zisko, Kjerstin Næss Skjerve, Atefe R Tari, Silvana Bucher Sandbakk, Ulrik Wisløff, Bjarne M Nes, Javaid Nauman
Prolonged sedentary behavior (SB) positively associates with clustering of risk factors for cardiovascular disease (CVD). The recently developed metric for physical activity (PA) tracking called Personal Activity Intelligence (PAI) takes into account age, sex, resting and maximum heart rate, and a score of ≥100 weekly PAI has been shown to reduce the risk of premature CVD death in healthy as well as individuals with known CVD risk factors, regardless of whether or not the current PA recommendations were met...
June 2017: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/28192133/global-fitness-levels-findings-from-a-web-based-surveillance-report
#20
REVIEW
Javaid Nauman, Lucas C Tauschek, Leonard A Kaminsky, Bjarne M Nes, Ulrik Wisløff
IMPORTANCE: Cardiorespiratory fitness (CRF) has shown to improve the classification beyond traditional risk factors and cumulative lifetime risk of death, however, there is no formal multicenter database that provides representative sample on a global scale to accurately interpret CRF measures. OBJECTIVE: The objective of the study was to describe worldwide web-surveillance data of CRF. DESIGN: Cross-sectional population based study. SETTING: Data was collected through a web-based questionnaire, including questions on country and city of residence, ethnicity, level of education, age, gender and anthropometric data such as height, weight, waistline, and maximal and resting pulse rate, on a freely available webpage (www...
June 2017: Progress in Cardiovascular Diseases
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