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Progress in Cardiovascular Diseases

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https://www.readbyqxmd.com/read/30321560/advanced-imaging-techniques-for-mitral-regurgitation
#1
REVIEW
Mary M Quien, Andrew F Vainrib, Robin S Freedberg, Daniel G Bamira, Ricardo J Benenstein, Matthew R Williams, Muhamed Saric
Mitral regurgitation (MR) is one of the most commonly encountered valvular lesions in clinical practice. MR can be either primary (degenerative) or secondary (functional) depending on the etiology of MR and the pathology of the mitral valve (MV). Echocardiography is the primary diagnostic tool for MR and is key in determining this etiology as well as MR severity. While clinicians usually turn to 2 Dimensional echocardiography as first-line imaging, 3 Dimensional echocardiography (3DE) has continually shown to be superior in terms of describing MV anatomy and pathology...
October 12, 2018: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/30236752/the-importance-of-school-based-healthy-living-initiatives-introducing-the-health-and-wellness-academy-concept
#2
REVIEW
Lindsey Strieter, Deepika R Laddu, Jenna Sainsbury, Ross Arena
Over the last 15 years, the number of school and community based health-intervention programs in the United States has grown. Many of these programs aim to prevent non-communicable chronic disease diagnoses (e.g., obesity, cardiovascular disease and type-2 diabetes). The Department of Physical Therapy in the College of Applied Health Sciences (CAHS) at the University of Illinois at Chicago (UIC) created a school-based wellness program (SBWP) that focuses on nutrition and physical activity, providing tailored experiences that motivate adolescents to make healthier lifestyle choices...
September 17, 2018: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/30236751/long-term-consequences-of-the-fontan-procedure-and-how-to-manage-them
#3
REVIEW
W Aaron Kay, Tabitha Moe, Blair Suter, Andrea Tennancour, Alice Chan, Richard A Krasuski, Ali N Zaidi
In 1971, Fontan and Baudet described a surgical technique for successful palliation of patients with tricuspid atresia. Subsequently, this technique has been applied to treat most forms of functional single ventricles and has become the current standard of care for long-term palliation of all patients with single ventricle congenital heart disease. Since 1971, the Fontan procedure has undergone several variations. These patients require lifelong management including a thorough knowledge of their anatomic substrate, hemodynamic status, management of rhythm and ventricular function along with multi organ evaluation...
September 17, 2018: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/30236750/transcatheter-valve-replacement-for-right-sided-valve-disease-in-congenital-heart-patients
#4
REVIEW
Jordan Gales, Richard A Krasuski, Gregory A Fleming
Pulmonary and/or tricuspid valve dysfunction is common among individuals with congenital heart disease, and surgical intervention often carries prohibitive risks. Transcatheter valve replacement (TVR) of the right-sided cardiac valves has become a viable treatment option over the past two decades, while continued technological development aims to broaden its applicability to an even larger portion of those with repaired congenital heart disease. To date, two transcatheter valves have been approved for use in patients with dysfunctional right ventricular to pulmonary artery conduits as well as those with failing pulmonic bioprosthetic valves, and are also used off-label in the "native" RVOT and within surgically repaired/replaced but failing tricuspid valves...
September 17, 2018: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/30227188/when-should-adult-congenital-heart-disease-patients-be-considered-for-transplant-and-deciding-which-organs-to-transplant
#5
REVIEW
Matthew Lewis, Marlon Rosenbaum
The number of adult congenital heart disease (ACHD) patients continues to increase. Because of multiple related factors such as aging, residual cardiac lesions and prior palliative procedures, advanced heart failure (HF) is increasingly prevalent in this population. Consequently, there is an emerging need to determine which patients are best suited for advanced cardiac therapies, including heart transplantation (HT) and mechanical circulatory support. Unfortunately, optimizing patient selection for these therapies is complicated by patient heterogeneity, variable HF presentation across lesion-type, and a paucity of outcome data...
September 15, 2018: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/30227187/meta-analysis-of-exercise-training-on-left-ventricular-ejection-fraction-in-heart-failure-with-reduced-ejection-fraction-a-10-year-update
#6
REVIEW
Wesley J Tucker, Rhys I Beaudry, Yuanyuan Liang, Alexander M Clark, Corey R Tomczak, Michael D Nelson, Oyvind Ellingsen, Mark J Haykowsky
BACKGROUND: The role of exercise training modality to attenuate left ventricular (LV) remodeling in heart failure patients with reduced ejection fraction (HFrEF) remains uncertain. The authors performed a systematic review and meta-analysis of published reports on exercise training (moderate-intensity continuous aerobic, high-intensity interval aerobic, and resistance exercise) and LV remodeling in clinically stable HFrEF patients. METHODS: We searched MEDLINE, Cochrane Central Registry of Controlled Trials, CINAHL, and PubMed (2007 to 2017) for randomized controlled trials of exercise training on resting LV ejection fraction (EF) and end-diastolic and end-systolic volumes in HFrEF patients...
September 15, 2018: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/30227186/long-term-outcomes-of-the-arterial-switch-operation-for-d-transposition-of-the-great-arteries
#7
REVIEW
Tabitha G Moe, Dianna M E Bardo
Dextrotransposition of the great arteries (d-TGA) is a relatively rare form of complex childhood congenital heart disease, which occurs in approximately 0.2 in 1000 live births1 . The most common palliative procedure for this anatomy has become the arterial switch operation (ASO). We will review in this paper the evidence that is currently available regarding the clinical management following the ASO. Individuals with d-TGA who undergo ASO at a young age thus far have excellent long-term outcomes. Long-term complications for the ASO should be monitored for and patients should have routine follow-up with specialists in adult congenital heart disease ...
September 15, 2018: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/30227185/temporal-changes-in-a-novel-metric-of-physical-activity-tracking-personal-activity-intelligence-and-mortality-the-hunt-study-norway
#8
REVIEW
Sophie K Kieffer, Ilaria Croci, Ulrik Wisløff, Javaid Nauman
BACKGROUND: Personal Activity Intelligence (PAI) is a novel activity metric that translates heart rate variations during exercise into a weekly score. Weekly PAI scores assessed at a single point in time were found to associate with lower risk of premature cardiovascular disease (CVD) mortality in the general healthy population. However, to date, the associations between long-term longitudinal changes in weekly PAI scores and mortality have not been explored. PURPOSE: The aim of the present study was to prospectively examine the association between change in weekly PAI scores estimated 10 years apart, and risk of mortality from CVD and all-causes...
September 15, 2018: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/30170697/sugar-wars-commentary-from-the-editor
#9
EDITORIAL
Carl J Lavie
No abstract text is available yet for this article.
August 28, 2018: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/30170696/the-demonization-of-diet-is-nothing-new
#10
LETTER
Edward Archer
No abstract text is available yet for this article.
August 28, 2018: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/30170695/in-critique-of-in-defense-of-sugar-the-nuance-of-whole-foods
#11
LETTER
James J DiNicolantonio, James H O'Keefe
No abstract text is available yet for this article.
August 28, 2018: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/30125582/epidemiology-of-achd-what-has-changed-and-what-is-changing
#12
REVIEW
Abigail Khan, Michelle Gurvitz
The worldwide population of adults with congenital heart disease (ACHD) has grown steadily over the last few decades, estimated at approximately 1.4 million people in 2010 (Gilboa et al., 2016). Innovations in surgical and medical treatment of children with congenital heart disease (CCHD) have dramatically improved survival, resulting in a growing population of ACHD patients with unique health needs (Marelli et al., 2014; Khairy et al., 2010). This growth has significant implications for health care providers and health systems, which must adapt to meet the demands of caring for this complex population...
August 17, 2018: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/30118722/neurocognitive-impairment-and-its-long-term-impact-on-adults-with-congenital-heart-disease
#13
REVIEW
Scott Cohen, Michael G Earing
It is well-recognized now that adult survivors with congenital heart disease (ACHD) are at risk for non-cardiac co-morbidities and complications that can impact symptoms and clinical outcomes. Cognitive dysfunction, in particular, is common in this population, but likely an under-recognized and undertreated cause for long-term morbidity. Abnormal cognitive function has a major impact on all aspects of quality of life, including employment opportunities, educational attainment, and the ability to maintain meaningful social relationships, such as marriage...
August 15, 2018: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/30107184/management-of-heart-failure-in-adult-congenital-heart-disease
#14
REVIEW
Angeline D Opina, Wayne J Franklin
Heart failure (HF) in the adult with congenital heart disease (ACHD) is associated with high morbidity and mortality and has been implicated as the leading cause of death in this patient population. The diagnosis of HF in ACHD involves a combination of clinical suspicion from subjective patient history, anatomic imaging, functional diagnostic studies, and rhythm evaluation. Once diagnosed, the approach to management of HF in this population varies widely and by lesion. Unfortunately, there is a paucity of literature available delineating the optimal management of these patients, making clinical decision-making extremely challenging...
August 11, 2018: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/30102921/family-planning-and-pregnancy-management-in-adults-with-congenital-heart-disease
#15
REVIEW
Kelly K Shum, Tripti Gupta, Mary M Canobbio, Jennifer Durst, Sangeeta B Shah
With advances in congenital heart disease management, there are an increasing number of women reaching reproductive age. Pregnancy results in a surge of hormones and increased demands on both the cardiovascular (CV) and respiratory systems. Depending on the heart defect and the treatments the mother has undergone, these hemodynamic changes can result in an increased risk of maternal CV events and an increased risk of fetal morbidity and mortality. Thus, it is important to have a comprehensive approach to adult congenital heart disease patients involving pre-pregnancy planning in addition to diligent peri- and post-partum care...
August 10, 2018: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/30041022/when-the-heart-is-not-to-blame-managing-lung-disease-in-adult-congenital-heart-disease
#16
REVIEW
Salil Ginde, Michael G Earing
It is well-recognized now that adult survivors with congenital heart disease (CHD) are at risk for non-cardiac co-morbidities and complications that can impact symptoms and clinical outcomes. Lung disease, in particular, is common in this population, but likely an under-recognized and undertreated cause for long-term morbidity. Abnormal lung function contributes to exercise intolerance and is associated with a higher risk for mortality in this population. The exact mechanisms that contribute to abnormal measurements of lung function are not entirely known, and are likely multifactorial and variable depending on the underlying CHD...
July 21, 2018: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/30041021/precise-therapy-for-thoracic-aortic-aneurysm-in-marfan-syndrome-a-puzzle-nearing-its-solution
#17
REVIEW
Erica Rurali, Gianluca Lorenzo Perrucci, Chiara Assunta Pilato, Alessandro Pini, Raffaella Gaetano, Patrizia Nigro, Giulio Pompilio
Marfan Syndrome (MFS) is a rare connective tissue disorder, resulting from mutations in the fibrillin-1 gene, characterized by pathologic phenotypes in multiple organs, the most detrimental of which affects the thoracic aorta. Indeed, thoracic aortic aneurysms (TAA), leading to acute dissection and rupture, are today the major cause of morbidity and mortality in adult MFS patients. Therefore, there is a compelling need for novel therapeutic strategies to delay TAA progression and counteract aortic dissection occurrence...
July 21, 2018: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/30041020/coronary-disease-and-modifying-cardiovascular-risk-in-adult-congenital-heart-disease-patients-should-general-guidelines-apply
#18
REVIEW
Jordan D Awerbach, Richard A Krasuski, Michael G W Camitta
There are >1.4 million adult congenital heart disease (CHD; ACHD) patients living in the United States. Coronary artery disease (CAD) is at least as prevalent in ACHD patients as in the general population and has become a leading cause of their mortality. In the majority of cases, CAD in the ACHD population is driven by the presence of traditional cardiovascular disease (CVD) risk factors. 80% of ACHD patients have at least one CVD risk factor. Hypertension (HTN), obesity and physical inactivity are frequently seen in both pediatric and adult patients with CHD...
July 21, 2018: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/30012407/depressive-and-anxiety-symptoms-in-adult-congenital-heart-disease-prevalence-health-impact-and-treatment
#19
REVIEW
Jamie L Jackson, Carine E Leslie, Shawn N Hondorp
Over 1.4 million adults in the United States are living with congenital heart disease (CHD), which can vary widely in disease burden and risk for future cardiovascular complications. As a result, some CHD survivors may experience greater emotional distress, including symptoms of depression and anxiety. This review summarizes the developing research literature on the prevalence, health impact, as well as screening and treatment of depressive and anxiety symptoms among adult CHD survivors. Additionally, the review will highlight findings from the acquired heart disease literature, a well-studied area that can inform research and clinical care practices for CHD survivors with depressive and/or anxiety symptoms...
July 20, 2018: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/30031004/transition-of-care-in-congenital-disease-allaying-fears-for-patients-and-specialists
#20
REVIEW
Timothy B Cotts
Advances in the care of infants and children with congenital heart disease (CHD) have resulted in significantly improved survival of this population into adulthood. Although the majority of patients with CHD have undergone surgical intervention or transcatheter intervention, patients are not "cured" and almost all require lifelong cardiac care. In many parts of the world, robust systems of care have been developed for infants and children with CHD. Although there has been progress in the development of programs for the care of adults with CHD, the time of transition and transfer of care remains a time of high risk for lapses in care and becoming lost to follow-up...
July 18, 2018: Progress in Cardiovascular Diseases
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