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Progress in Cardiovascular Diseases

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https://www.readbyqxmd.com/read/29678447/mediterranean-diet-and-cardiovascular-disease-prevention-what-do-we-know
#1
REVIEW
Jordi Salas-Salvadó, Nerea Becerra-Tomás, Jesús Francisco García-Gavilán, Mònica Bulló, Laura Barrubés
Cardiovascular disease (CVD) morbidity and mortality is increasing, representing an important public health issue worldwide. It is well-known that risk of CVD is substantially influenced by lifestyle, including poor diet, tobacco smoking and physical inactivity. In the last years, the so-called Mediterranean Diet (MedDiet) has been associated with broad healthy benefits on human health, including protection against CVD. The present narrative review aimed to summarize and discuss the evidence from meta-analyses of epidemiological and clinical trials analyzing MedDiet and CVD risk...
April 17, 2018: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/29634958/anticoagulation-beyond-3-to-6-months-what-does-the-data-tell-us
#2
REVIEW
Teresa L Carman
Patients with a history of deep vein thrombosis and pulmonary embolism are at risk for a recurrent event. This is particularly true of patients with idiopathic events or events related to low risk triggers. In these patients extending anticoagulation beyond 3 to 6 months may be warranted. Using clinical risk, biomarker analysis and risk stratification protocols we can make the best recommendations to patients with respect to the risks and benefits of ongoing therapy. Trials demonstrating benefit from low-dose aspirin for secondary prophylaxis may provide an option for patients in whom ongoing anticoagulation is deemed unsafe...
April 7, 2018: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/29630905/introduction-to-the-vascular-medicine-issue-of-progress-in-cardiovascular-diseases
#3
EDITORIAL
Esther S H Kim, Joshua A Beckman
No abstract text is available yet for this article.
April 6, 2018: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/29630904/spontaneous-coronary-artery-dissection-cardiac-manifestations-of-vascular-disease
#4
REVIEW
Vineet Agrawal, Esther S H Kim
Spontaneous coronary artery dissection (SCAD) is an increasingly recognized cause of acute coronary syndrome (ACS) in young women who otherwise do not have traditional risk factors for coronary artery disease. Though previously considered to be a rare occurrence and primarily associated with pregnancy, contemporary series have demonstrated that SCAD may account for 35% of ACS in women under the age of 50 years, and peripartum SCAD accounts for the minority of cases. Importantly, an association between SCAD and arterial abnormalities in non-coronary arterial distributions has been described...
April 6, 2018: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/29571892/omega-3-polyunsaturated-fatty-acids-and-cardiovascular-health-a-comprehensive-review
#5
REVIEW
Andrew Elagizi, Carl J Lavie, Keri Marshall, James J DiNicolantonio, James H O'Keefe, Richard V Milani
The potential cardiovascular (CV) disease (CVD) benefits of Omega-3 Polyunsaturated Fatty Acids (OM3) have been intensely studied and debated for decades. Initial trials were performed in patients with low use of maximal medical therapy for CVD, and reported significant mortality benefits with the use of 1 g/day OM3 intervention following myocardial infarction (MI). More recent studies, including cohorts of patients receiving modern guideline directed medical therapy for CVD, have often not shown similar benefits with OM3 use...
March 20, 2018: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/29551418/combined-effect-of-sauna-bathing-and-cardiorespiratory-fitness-on-the-risk-of-sudden-cardiac-deaths-in-caucasian-men-a-long-term-prospective-cohort-study
#6
REVIEW
Jari A Laukkanen, Tanjaniina Laukkanen, Hassan Khan, Maira Babar, Setor K Kunutsor
Both cardiorespiratory fitness (CRF) and frequency of sauna bathing (FSB) are each strongly and independently associated with sudden cardiac death (SCD) risk. However, the combined effect of CRF and FSB on SCD risk has not been previously investigated. We evaluated the joint impact of CRF and FSB on the risk of SCD in the Kuopio Ischemic Heart Disease prospective cohort study of 2291 men aged 42-61 years at recruitment. Objectively measured CRF and self-reported sauna bathing habits were assessed at baseline...
March 15, 2018: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/29534986/peri-procedural-management-of-oral-anticoagulants-in-the-doac-era
#7
REVIEW
Geoffrey D Barnes, Erin Mouland
Peri-procedural management of oral anticoagulants can be complex and confusing for many providers. It involves a careful balance of a patient's thromboembolic risk and bleeding risk. For every patient chronically taking an oral anticoagulant who will be undergoing an elective procedure, a four step approach may be considered when creating a plan for the oral anticoagulant.(Writing Group M, 20161 ) Does the oral anticoagulant need to stop for the procedure?(Periprocedural Management of Anticoagulation Writing C, Doherty JU, Gluckman TJ, et al...
March 10, 2018: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/29534985/next-generation-endovascular-therapies-in-peripheral-artery-disease
#8
REVIEW
Matthew C Bunte, Mehdi H Shishehbor
Endovascular therapy (EVT) of symptomatic peripheral artery disease (PAD) offers relief of symptoms and enhanced quality of life. Advancements in technique and technology have increased the feasibility and practicality of EVT, which now represents the preferred mode of revascularization over surgical procedures in many centers across the world. In this review, we consider the future of EVT in context of a rapidly expanding population of patients with symptomatic PAD.
March 10, 2018: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/29534984/fibromuscular-dysplasia-contemporary-concepts-and-future-directions
#9
REVIEW
Nupoor Narula, Daniella Kadian-Dodov, Jeffrey W Olin
Fibromuscular dyplasia (FMD) is an under-recognized non-atherosclerotic, non-inflammatory arteriopathy that occurs most commonly in middle-aged women, but may affect individuals of all age groups. FMD may result in stenosis, aneurysm, dissection, occlusion, or arterial tortuosity. Recently published data demonstrated a genetic association of FMD with a variant in the phosphatase and actin regulator 1 gene (PHACTR1), substantiating that the pathogenesis of this condition has genetic contribution. The renal and extracranial carotid and vertebral arteries are most often involved, although any arterial bed may be affected...
March 10, 2018: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/29534983/cutaneous-manifestations-of-chronic-vascular-disease
#10
REVIEW
Steven M Dean
In the contemporary era of medical diagnosis via sophisticated radiographic imaging and/or comprehensive serological testing, a focused physical examination remains paramount in recognizing the cutaneous manifestations of chronic vascular disease. Recognition of the unique cutaneous signs of lymphatic and venous hypertension assists in the diagnosis as well as the staging and classification of both lymphedema and chronic venous insufficiency. Awareness of explicit dermatologic vasomotor manifestations aids not only in the identification of acrocyanosis, Raynaud phenomenon, pernio, and erythromelalgia but also mitigates confusion related to their clinical overlap...
March 10, 2018: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/29474816/coffee-for-cardioprotection-and-longevity
#11
REVIEW
James H O'Keefe, James J DiNicolantonio, Carl J Lavie
Coffee, a complex brew containing hundreds of biologically active compounds, exerts potent effects on long-term human health. Recently, a plethora of studies have been published focusing on health outcomes associated with coffee intake. An inverse association between coffee consumption and all-cause mortality has been seen consistently in large prospective studies. Habitual coffee consumption is also associated with lower risks for cardiovascular (CV) death and a variety of adverse CV outcomes, including coronary heart disease (CHD), congestive heart failure (HF), and stroke; coffee's effects on arrhythmias and hypertension are neutral...
February 20, 2018: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/29458056/alcohol-and-cv-health-jekyll-and-hyde-j-curves
#12
REVIEW
Evan L O'Keefe, James J Di Nicolantonio, James H O'Keefe, Carl J Lavie
A routine of light or moderate alcohol consumption (≤1 drink/day for women and 1 to 2 drinks/day for men) were associated with a lower risk for all-cause mortality, coronary artery disease (CAD), type 2 diabetes mellitus (T2D), heart failure (HF), and stroke. Conversely, heavy drinking, (>4 drinks/day) is associated with an increased risk for death and cardiovascular (CV) disease (CVD). Excessive alcohol intake trails behind only smoking and obesity among the 3 leading causes of premature deaths in the United States (US)...
February 16, 2018: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/29452135/evidence-based-exercise-recommendations-to-reduce-hepatic-fat-content-in-youth-a-systematic-review-and-meta-analysis
#13
REVIEW
María Medrano, Cristina Cadenas-Sanchez, Celia Álvarez-Bueno, Iván Cavero-Redondo, Jonatan R Ruiz, Francisco B Ortega, Idoia Labayen
The main purposes of this study were to elucidate the effects of supervised-exercise training (ET) interventions on hepatic fat content and on non-alcoholic fatty liver disease (NAFLD) prevalence in children and adolescents and to provide information about the optimal ET prescription (type, intensity, volume, and frequency) needed to reduce hepatic fat content in youths. Supervised-ET interventions performed in children and adolescents (6-19 years) that provided results of exercise effects on hepatic fat content or NAFLD prevalence were included...
February 13, 2018: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/29452134/effect-of-high-intensity-interval-training-on-cardiac-function-in-children-with-obesity-a-randomised-controlled-trial
#14
REVIEW
Charlotte B Ingul, Katrin A Dias, Arnt E Tjonna, Turid Follestad, Mansoureh S Hosseini, Anita S Timilsina, Siri M Hollekim-Strand, Torstein B Ro, Peter S W Davies, Peter A Cain, Gary M Leong, Jeff S Coombes
BACKGROUND: High intensity interval training (HIIT) confers superior cardiovascular health benefits to moderate intensity continuous training (MICT) in adults and may be efficacious for improving diminished cardiac function in obese children. The aim of this study was to compare the effects of HIIT, MICT and nutrition advice interventions on resting left ventricular (LV) peak systolic tissue velocity (S') in obese children. METHODS: Ninety-nine obese children were randomised into one of three 12-week interventions, 1) HIIT [n = 33, 4 × 4 min bouts at 85-95% maximum heart rate (HR max ), 3 times/week] and nutrition advice, 2) MICT [n = 32, 44 mins at 60-70% HR max , 3 times/week] and nutrition advice, and 3) nutrition advice only (nutrition) [n = 34]...
February 13, 2018: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/29397950/triple-antithrombotic-therapy-for-patients-with-atrial-fibrillation-undergoing-percutaneous-coronary-intervention
#15
REVIEW
Mathieu Kerneis, Usama Talib, Tarek Nafee, Yazan Daaboul, Seyedmahdi Pahlavani, Anmol Pitliya, M M Furqan, Sudarshana Datta, Hassan A Kazmi, Ahmed Younes, C Michael Gibson
Dual antiplatelet therapy (DAPT) has been the cornerstone of antithrombotic management for patients undergoing percutaneous coronary intervention (PCI). However, approximately 10% of these patients have concomitant atrial fibrillation (AF) and require chronic oral anticoagulant (OAC) in addition to DAPT. This traditional "triple therapy" has been associated with a three to four-fold increased risk of bleeding. The safety of non-vitamin K OAC (NOAC)-based strategies, using a NOAC plus a P2Y12 inhibitor, has been compared to vitamin K antagonist (VKA)-based triple therapy in the PIONEER AF-PCI and REDUAL PCI randomized trials, both of which have demonstrated that NOAC-based strategies are safer and provide an attractive alternative to VKA-based triple therapy among AF patients who undergo PCI...
February 2, 2018: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/29409813/duration-of-dual-antiplatelet-therapy-for-stented-patients-an-update-for-the-clinician
#16
REVIEW
Mahesh K Vidula, Eric A Secemsky, Robert W Yeh
Determining the optimal duration of dual antiplatelet therapy (DAPT) following percutaneous coronary intervention is a complex decision. Randomized controlled trials have shown that while shorter durations of DAPT may lower the risk of bleeding, longer durations of DAPT can reduce the risk of late stent thrombosis and ischemia-related events. In this review article, we will discuss the current guidelines, review contemporary trial data that have evaluated short and extended durations of DAPT, and address common clinical questions...
February 1, 2018: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/29360523/thiamine-and-cardiovascular-disease-a-literature-review
#17
REVIEW
James J DiNicolantonio, Jing Liu, James H O'Keefe
Thiamine is a water-soluble vitamin that plays an important role in the energy metabolism in the human body. Deficiency in thiamine can lead to neurological abnormalities and congestive heart failure (HF), known as dry beriberi and wet beriberi respectively. Several populations are at higher risk for thiamine deficiency, most notably persons with chronic alcoholism. This article aims to provide a review of current literature on the role of thiamine in the human body, the current scope of thiamine deficiency, and explore the specific effects of thiamine deficiency and supplementation on the cardiovascular system...
January 31, 2018: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/29341881/clinical-implications-of-technological-advances-in-screening-for-atrial-fibrillation
#18
REVIEW
Nikhil Singh, Sung Chun, David Hadley, Victor Froelicher
The incidence of atrial fibrillation (AF) continues to increase worldwide as people live longer. AF is the leading cause of stroke among patients older than 75 years and is responsible for at least 15% of all strokes. Industry has responded to this problem with a plethora of monitoring devices. These include single lead ECG adhesive sensors, implantable loop recorders, smartphone attachments and wearables. This review will concentrate on clinical studies using these technologies. There are wearables including watches and watch-like devices that will be mentioned but these have not been validated for clinical use...
January 13, 2018: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/29366879/the-waxing-and-waning-of-antithrombotic-therapy-in-cardiovascular-disease-where-is-the-moon-now
#19
EDITORIAL
Mark B Effron, C Michael Gibson
No abstract text is available yet for this article.
January 2018: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/29360524/dual-anticoagulant-plus-single-antiplatelet-vs-triple-anticoagulant-plus-dual-antiplatelet-antithrombotic-therapy-real-world-experience
#20
REVIEW
Mark B Effron, C Michael Gibson
Atrial fibrillation (AF) is a common arrhythmia that increases in prevalence with advancing age and in patients with coronary artery disease, revascularization, particularly with percutaneous coronary intervention (PCI), is also common. Both disease states have thrombosis as a core pathophysiologic process which requires treatment - low sheer stress thrombi in AF and intracoronary high sheer stress thrombi in PCI. For the 10-20% of patients who have both AF and undergo PCI, preventing thrombotic complications will require inhibition of both processes requiring simultaneous use of anticoagulation and antiplatelet therapy...
January 2018: Progress in Cardiovascular Diseases
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