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Journal of Urology

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https://www.readbyqxmd.com/read/28327453/combining-transcutaneous-electrical-nerve-stimulation-tens-with-oxybutynin-is-superior-to-monotherapy-in-children-with-urge-incontinence-a-randomized-placebo-controlled-study
#1
L Borch, S Hagstroem, K Kamperis, C V Siggaard, S Rittig
PURPOSE: To evaluate if combination therapy with TENS and oxybutynin results in a superior treatment response than monotherapy with the two modalities in childhood urge incontinence. MATERIALS AND METHODS: In this placebo-controlled study 66 urge incontinent children (mean age 7.3 ± 1.6 years) were randomized into three treatment groups. Group 1: active TENS + active oxybutynin (n = 22). Group 2: active TENS + placebo oxybutynin (n = 21). Group 3: active oxybutynin + placebo TENS (n = 23)...
March 18, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28325669/a-pediatric-urology-wish-list-for-spina-bifida-research
#2
EDITORIAL
Jonathan C Routh
No abstract text is available yet for this article.
March 18, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28325668/robot-assisted-laparoscopic-extravesical-ureteral-reimplantation-for-primary-vesicoureteral-reflux-in-children
#3
EDITORIAL
Glenn M Cannon, Michael C Ost
No abstract text is available yet for this article.
March 18, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28322857/vascular-targeted-photodynamic-therapy-with-padeliporfin-for-low-risk-prostate-cancer-treatment-mid-term-oncological-outcomes
#4
Souhil Lebdai, Pierre Bigot, Pierre-Adrien Leroux, Louis-Paul Berthelot, Pierre Maulaz, Abdel-Rahmene Azzouzi
PURPOSE: To assess the mid-term oncological outcomes of vascular-targeted photodynamic therapy with padeliporfin for low-risk prostate cancer treatment. MATERIAL AND METHODS: We prospectively assessed all patients treated with vascular-targeted photodynamic therapy for low-risk prostate cancer in our center. Patients were followed every 6 months. All patients underwent prostate biopsies 6 months post-treatment or in case of biological or clinical progression. Primary endpoint was the progression-free survival...
March 18, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28322856/orgasmic-function-after-radical-prostatectomy
#5
Kefu Du, Chong Zhang, Angela P Presson, Jonathan D Tward, William O Brant, Christopher B Dechet
PURPOSE: We examined post-prostatectomy orgasmic function (OF) and assessed for potential predictors. MATERIALS AND METHODS: Between 2005 and 2013, 499 men underwent radical prostatectomy and completed quality of life questionnaires prospectively preoperatively and at regular postoperative intervals. We used mixed effects logistic regression models to evaluate average differences in follow-up measures and interactions with time. RESULTS: At a median follow-up of 36 months, OF was worsened, stable, or improved in 300 (60...
March 18, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28322195/choosing-the-right-intervention-for-treatment-of-lower-urinary-tract-symptoms-in-men
#6
EDITORIAL
Henry H Woo
No abstract text is available yet for this article.
March 16, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28322194/erratum
#7
(no author information available yet)
No abstract text is available yet for this article.
March 16, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28322193/editorial-comment
#8
Hann-Chorng Kuo
No abstract text is available yet for this article.
March 16, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28322192/editorial-comment
#9
Michael B Chancellor
No abstract text is available yet for this article.
March 16, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28288839/the-role-of-high-dose-interleukin-2-in-the-era-of-targeted-therapy
#10
Jessie Gills, William P Parker, Scott Pate, Sida Niu, Peter Van Veldhuizen, Moben Mirza, Jeffery M Holzbeierlein, Eugene K Lee
OBJECTIVE: To assess survival outcomes following high dose IL-2 (HDIL-2) in a contemporary cohort of patients during the era of targeted agents. METHODS: Retrospective review of metastatic RCC patients treated with HDIL-2 between July 2007 and September 2014. Clinicopathologic data were abstracted and patient response to therapy was based on RECIST v1.1 criteria. The Kaplan-Meier method was used to estimate progression-free survival (PFS) and overall survival (OS) for the entire cohort, response to HDIL-2 in regards to previous targeted agent therapy, and response to targeted agent in relationship to response to HDIL-2...
March 10, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28288838/routine-ertapenem-prophylaxis-for-transrectal-ultrasound-guided-prostate-biopsy-does-not-select-for-carbapenem-resistant-organisms-a-prospective-cohort-study
#11
Maxim G Bloomfield, Matthew J Page, Alice G McLachlan, Rodney C Studd, Timothy K Blackmore
PURPOSE: Post-transrectal ultrasound-guided prostate biopsy sepsis is an increasing problem in this era of rising antibiotic resistance. Ertapenem prophylaxis has proven very effective at our institution for reducing this, however has raised local and regional antimicrobial stewardship concerns. This study investigated the possible selective effect of single dose ertapenem prophylaxis on fecal colonization with carbapenem-resistant Enterobacteriaceae. MATERIALS AND METHODS: Patients had a rectal swab taken prior to receiving pre-biopsy ertapenem prophylaxis...
March 10, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28288837/can-cranberries-contribute-to-reduce-the-incidence-of-urinary-tract-infections-a-systematic-review-with-meta-analysis-and-trial-sequential-analysis-of-clinical-trials
#12
Ângelo Luís, Fernanda Domingues, Luísa Pereira
PURPOSE: To clarify the association between cranberries intake and the prevention of urinary tract infections (UTIs). METHODS: It was performed a systematic review, complied with the PRISMA (Preferred Reporting Items for Systematic Review and Meta-Analysis) statement, followed by a meta-analysis and trial sequential analysis (TSA) of clinical trials. RESULTS: The results clearly show the potential use of cranberries in a clinical condition of UTI...
March 10, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28286074/human-penile-transplantation-an-emerging-therapy-for-genitourinary-reconstruction
#13
REVIEW
Nikolai A Sopko, Sami H Tuffaha, Denver Lough, Gerald Brandacher, W P Andrew Lee, Trinity J Bivalacqua, Richard J Redett, Arthur L Burnett
PURPOSE: Reconstruction of complex functional structures is increasingly being performed with vascularized composite allo-transplantation (VCA). Penile transplantation is a novel VCA treatment option for severe penile tissue loss and disfigurement. Three allogeneic human penile transplantations have been reported. We review these cases as well as penile transplant indications, pre-clinical models, and immunosuppression therapy. MATERIALS AND METHODS: We performed a comprehensive literature review for the years 1970 to 2016 via MEDLINE, PubMed, and Google with the key words "penis transplantation", "penile rejection", "penile replantation", "penile tissue loss", and "penis vascularized composite allo-transplantation"...
March 9, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28286073/intermediate-term-outcomes-and-complications-of-long-segment-urethroplasty-with-lingual-mucosa-grafts
#14
Yue-Min Xu, Chao Li, Hong Xie, Ying-Long Sa, Qiang Fu, Deng-Long Wu, Jiong Zhang, Chao Feng, Chong-Rui Jin, Lu-Jie Song, Hong-Bin Li, Ying Liu
PURPOSE: We evaluated the outcomes and donor site complications of male patients with complex urethral strictures (CUS) that underwent urethroplasty by using with long-strip oral mucosal grafts (OMGs). The study analyzed whether lingual mucosa graft (LMG) is a good substitute for repairing long segment urethral strictures. MATERIALS AND METHODS: This was a retrospective study of 81 male patients with CUS that underwent OMGs urethroplasty. Patients with long segment anterior urethral strictures(≥8 cm)that were considered for long-strip LMG urethroplasty were included in the study...
March 9, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28286072/organ-sparing-surgery-in-penile-cancer-a-systematic-review
#15
REVIEW
Mohamed H Kamel, Nabil Bissada, Renee Warford, Judy Farias, Rodney Davis
PURPOSE: Although penile cancer (PC) only represents 1% of all male cancers, the traditional treatment of total or subtotal penectomy carries devastating psychological and functional outcomes. Organ sparing surgery (OSS) in PC is an attractive option if it can provide satisfactory cancer control equivocal or near equivocal to standard techniques. In fact, these techniques are meeting increasing acceptance. Accordingly, the need to evaluate these options objectively is crucial in a comprehensive review is timely in order to increase awareness of these procedures, their applicability and provide guidance to the practicing urologist...
March 9, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28286071/bosniak-classification-for-complex-renal-cysts-re-evaluated-a-systematic-review
#16
REVIEW
Ivo G Schoots, Keren Zaccai, Myriam G Hunink, Paul C M S Verhagen
OBJECTIVE: To systematically evaluate the Bosniak classification, with malignancy rates of each Bosniak category, and to assess the effectiveness related to surgical treatment and oncological outcome, based on recurrence and/or metastasis. METHODS: A systematic review (according to the PRISMA statement and the QUADAS-2 criteria) selected 39 publications for inclusion in this analysis and categorised into: 1) "surgical" cohorts- all cysts underwent surgery, and 2) "radiological" cohorts- cysts underwent either surgical treatment or radiological follow-up...
March 9, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28286070/the-risk-of-chronic-kidney-disease-associated-with-urolithiasis-and-its-urological-treatments-a-review
#17
REVIEW
Giovanni Gambaro, Emanuele Croppi, David Bushinsky, Philippe Jaeger, Adamasco Cupisti, Andrea Ticinesi, Sandro Mazzaferro, Alessandro D'Addessi, Pietro Manuel Ferraro
PURPOSE: Urolithiasis can impair kidney function. This literature review focuses on the risk of kidney impairment in stone formers, the specific conditions associated with this risk and the impact of urological surgery. MATERIALS AND METHODS: The PubMed and Embase databases were searched for publications on urolithiasis, its treatment, and the risk of chronic kidney disease (CKD), end-stage renal disease (ESRD) and nephrectomy in stone formers. RESULTS: In general, renal stone formers carry twice the risk of CKD or ESRD, and for female and overweight stone formers the risk is even higher...
March 9, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28286069/the-risks-and-benefits-of-cavernosal-neurovascular-bundle-sparing-during-radical-prostatectomy-a-systematic-review-and-meta-analysis
#18
REVIEW
Laura N Nguyen, Linden Head, Kelsey Witiuk, Nahid Punjani, Ranjeeta Mallick, Sonya Cnossen, Dean A Fergusson, Ilias Cagiannos, Luke T Lavallée, Christopher Morash, Rodney H Breau
PURPOSE: Our objective was to summarize published data on associations between cavernosal neurovascular bundle preservation (nerve spare) and positive surgical margins, erectile function, urinary function, and other patient reported outcomes. MATERIALS AND METHODS: A systematic literature search of Medline, EMBASE, and Cochrane Reviews databases was performed for interventional or observational studies published between 2000-2014. English-language articles that compared clinical outcomes of patients undergoing nerve-sparing and non-nerve-sparing radical prostatectomy were included...
March 9, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28286068/efficacy-of-bacillus-calmette-guerin-strains-for-the-treatment-of-non-muscle-invasive-bladder-cancer-a-systematic-review-and-network-meta-analysis
#19
REVIEW
Brock E Boehm, John E Cornell, Hanzhang Wang, Neelam Mukherjee, Jacob S Oppenheimer, Robert S Svatek
PURPOSE: To determine the efficacy of genetically distinct Bacillus Calmette-Guérin (BCG) strains in preventing disease recurrence for patients with non-muscle invasive bladder cancer (NMIBC). EXPERIMENTAL DESIGN: We conducted a systematic review and network meta-analysis of trials evaluating BCG strains against all possible comparators (different BCG strains, chemotherapy, and non-BCG biologic therapies) and intravesical chemotherapy as the common comparator. MEDLINE served as the primary data source, with search from inception to October 2016 for clinical trials involving patients with NMIBC receiving BCG...
March 9, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28286067/future-directions-of-research-and-care-for-urinary-incontinence-in-women-findings-from-the-national-institute-of-diabetes-and-digestive-and-kidney-diseases-niddk-summit-on-urinary-incontinence-clinical-research-in-women
#20
REVIEW
Toby C Chai, Tirsit S Asfaw, Jan E Baker, Becky Clarkson, Pamela Coleman, Susan Hoffstetter, Kimberly Konkel, Missy Lavender, Shailaja Nair, Jenna Norton, Leslee Subak, Anthony Visco, Robert A Star, Tamara Bavendam
PURPOSE: Female urinary incontinence (UI) is prevalent, costly, and morbid. Participants in an NIDDK-sponsored summit reviewed findings from NIH-funded clinical research in UI and discussed the future of UI research. MATERIALS AND METHODS: On March 14 2014, the NIDDK convened a "Summit on Urinary Incontinence Clinical Research in Women." Participants representing a broad range of clinical expertise reviewed completed, NIH-sponsored UI-related studies, including results from community-based, epidemiologic studies such as the Boston Area Community Health (BACH) Survey and from randomized clinical trials such as the Program to Reduce Incontinence by Diet and Exercise (PRIDE) and studies conducted by the Pelvic Floor Disorders Network (PFDN) and the Urinary Incontinence Treatment Network (UITN)...
March 9, 2017: Journal of Urology
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