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Kardiologia Polska

Fang-Fei Wei, Zhen-Yu Zhang, Qi-Fang Huang, Wen-Yi Yang, Jan A Staessen
The publication of the first non-randomised proof-of-concept trial of renal denervation as a treatment modality in treatment-resistant hypertension set the stage for a search for novel devices with the expectation that technology would reduce the burden of hypertension by reducing or eliminating the costly and lifelong use of blood pressure lowering medications. As we demonstrate in this review, this idea so attractive to manufacturers and invasive cardiologists and radiologists overlooked decades of careful pathophysiological research in a disease, which still remains enigmatic but remains the major cause of cardiovascular mortality worldwide...
June 15, 2018: Kardiologia Polska
Mateusz T Knop, Jacek Białkowski, Małgorzata Szkutnik, Roland Fiszer, Sebastian Smerdziński, Michał Gałeczka, Linda Litwin
BACKGROUND: Atrial septal defect type II (ASD), according to current standards, is closed percutaneously usually after the child has reached the age of 4-5 years. There are limited data regarding such treatment in smaller infants. AIMS: To evaluate feasibility, safety and efficacy of percutaneous ASD closure in children under 3 years of age. METHODS: Overall group of 149 children < 3 years with hemodynamically significant ASD, who underwent effective transcatheter ASD closure in one tertiary center between 1999 and 2014 were included...
June 4, 2018: Kardiologia Polska
Qiming Wang, Jian Zhang, Yafei Li, Haojie Shi, Hao Wang, Bingrui Chen, Fang Wang, Zemu Wang, Zhijian Yang, Liansheng Wang
BACKGROUND: Epigallocatechin-3-gallate (EGCG), which is the principal component of green tea, has been shown to prevent the formation of atherosclerosis. However, the effect of EGCG on atherosclerotic plaque stability remains unknown. AIM: This study aimed to assess whether EGCG can enhance atherosclerotic plaque stability and to investigate the underlying mechanisms. METHODS: Apolipoprotein E-deficient mice fed a high-fat diet were injected intraperitoneally with EGCG (10 mg/kg ) for 16 weeks...
June 4, 2018: Kardiologia Polska
Arkadiusz Retwiński, Marcin Kosmalski, Marisa Crespo-Leiro, Aldo Maggioni, Grzegorz Opolski, Piotr Ponikowski, Lech Poloński, Ewa Jankowska, Jerzy Drzewoski, Jarosław Drożdż
BACKGROUND: Metformin (MET) is one of antihyperglycaemic substances that reduces risk of major cardiovascular events, including fatal ones. Although it is formally contraindicated in moderate and severe functional stages of heart failure (HF), it is commonly used in patients with concomitant type 2 diabetes mellitus (T2DM). AIM: Evaluation of the effect of MET and T2DM on total mortality and hospitalization rates in patients with HF. METHODS: 1030 adult patients (>18 years) with HF from the Polish section of HF Long-Term Registry were included in years 2011-2014 into this retrospective analysis...
June 4, 2018: Kardiologia Polska
Rafał Dankowski, Tomasz Kotwica, Andrzej Szyszka, Monika Przewłocka-Kosmala, Wioletta Sacharczuk, Bożena Karolko, Małgorzata Kobusiak-Prokopowicz, Andrzej Mysiak, Wojciech Kosmala
BACKGROUND: The determinants of the impact of mineralocorticoid receptor antagonism (MRA) on exercise tolerance in heart failure with reduced ejection fraction (HFrEF) have not been sufficiently characterized. AIMS: We sought to investigate the factors associated with improvement in exercise capacity following the introduction of spironolactone to therapy in HFrEF patients, as well as to assess the linkage between improvement in exercise capacity and changes in cardiac functional characteristics with treatment...
June 4, 2018: Kardiologia Polska
Christine M DeStephan, David J Schneider
Considerable variation in the use and duration of antiplatelet medications during the perioperative and postoperative care of patients undergoing coronary artery bypass grafting (CABG) reflects limited studies focused directly on these patients as well as variation in the results reported. In this review we will highlight the incidence and mechanisms of graft closure as well as the evidence in support of antiplatelet therapy that is balanced by the impact of antiplatelet therapy on the risk of bleeding to provide recommendations for the use of antiplatelet therapy in patients undergoing CABG...
May 21, 2018: Kardiologia Polska
Mark Crowther, John Eikelboom
Dual antiplatelet therapy (DAPT) has been the cornerstone of antithrombotic management for patients undergoing percutaneous coronary intervention (PCI). Despite low-quality evidence, triple antithrombotic therapy involving acetylsalicylic acid, clopidogrel and warfarin or non-vitamin K antagonist oral anticoagulant (NOAC) has been recommended in patients with concomitant atrial fibrillation undergoing PCI, who require long-term oral anticoagulation, although such strategy is associated with a substantially increased risk of bleeding compared with DAPT...
May 21, 2018: Kardiologia Polska
Mariusz Tomaniak, Janusz Kochman, Łukasz Kołtowski, Arkadiusz Pietrasik, Adam Rdzanek, Jacek Jąkała, Klaudia Proniewska, Krzysztof Malinowski, Dorota Ochijewicz, Krzysztof J Filipiak, Salvatore Brugaletta, Grzegorz Opolski
BACKGROUND: Early-generation drug-eluting stents (DES) have been shown to accelerate neoatherogenesis. Limited optical coherence tomography (OCT) data on the very long-term neoatherosclerosis progression after DES implantation are available. AIM: The aim of this study was a serial OCT evaluation of neoatherosclerosis at 3 and 9 years after implantation of sirolimus-eluting stents (SES) and paclitaxel-eluting stents (PES). METHODS: Consecutive patients undergoing elective PCI with SES (Cypher, Cordis) or PES (Taxus, Boston Scientific) were included in this single-centre, longitudinal study...
May 11, 2018: Kardiologia Polska
Anna H Skoczyńska, Ewa Gluza, Anna Wojakowska, Barbara Turczyn, Marta Skoczyńska
BACKGROUND: Linseed oil has cardio-protective effects. However, its antihypertensive action has not yet been well characterized. AIM: The primary purpose of the study was to evaluate the effect of short-term dietary supplementation with linseed oil on blood pressure (BP) and lipid metabolism in patients with mild hypercholesterolemia. The secondary aim was to evaluate the effect of linseed oil on nitric oxide pathway and selected serum trace metals. METHODS: 150 volunteers: 43 men (49...
April 24, 2018: Kardiologia Polska
Maciej Dębski, Mateusz Ulman, Andrzej Ząbek, Krzysztof Boczar, Kazimierz Haberka, Marcin Kuniewicz, Jacek Lelakowski, Barbara Małecka
BACKGROUND: Pacing leads remain the weakest link in pacemaker systems despite advances in manufacturing technology. AIM: To assess the long-term pacing lead performance in an unselected real-life cohort following primary DDD pacing system implantation. METHODS: A single-centre retrospective analysis of patients who underwent DDD pacing system implantation between October 1984 and December 2014 and were followed up until August 2016 was conducted...
April 10, 2018: Kardiologia Polska
Wioletta Szczurek, Bożena Szyguła-Jurkiewicz, Michał Wojciech Zakliczyński, Bogumiła Król, Mariusz Gąsior, Marian Zembala
BACKGROUND: Due to the increasing number of patients placed on waiting lists for orthotopic heart transplantation (OHT), the selection of patients with the highest risk of death becomes paramount. AIM: This study sought to evaluate the predictive value of the MELD-XI (Model for End-Stage Liver Disease excluding INR) and MAGGIC (Meta-Analysis Global Group in Chronic Heart Failure) scales in ambulatory patients awaiting OHT and compare them to the HFSS (Heart Failure Survival Score)...
April 10, 2018: Kardiologia Polska
Michał Orczykowski, Karolina Borowiec, Elzbieta Biernacka, Robert Bodalski, Piotr Urbanek, Pawel Derejko, Katarzyna Kodziszewska, Olgierd Wozniak, Aneta Fronczak, Kamil Marcinkiewicz, Krystyna Guzek, Agnieszka Fil, Grzegorz Warminski, Piotr Hoffman, Maria Bilinska, Lukasz Szumowski
BACKGROUND: After the surgical correction of Tetralogy of Fallot (TOF), surgical scars and natural obstacles form pathways capable of supporting an atrial tachyarrhythmia (AT). Radiofrequency ablation is effective, although the few studies to date on this topic had relatively short follow-up periods. AIM: The aims of the study were to evaluate the acute and long-term effects of RF ablation of AT and examine the characteristics of arrhythmia recurrence. METHODS: Tetralogy of Fallot patients (N 16, age 44...
March 14, 2018: Kardiologia Polska
Małgorzata Konieczyńska, Ewa Sobieraj, Agata Hanna Bryk, Maciej Dębski, Maciej Polak, Piotr Podolec, Barbara Małecka, Andrzej Pająk, Lien Desteghe, Hein Heidbuchel, Anetta Undas
BACKGROUND: Non-vitamin K antagonist oral anticoagulants (NOACs) are increasingly used for stroke prevention in patients with atrial fibrillation (AF) worldwide. Few articles have compared current understanding of AF patients about the disease and anticoagulant therapy in relation to the medications used. AIM: The aim of this study was to compare the knowledge of AF and anticoagulation between AF patients treated with NOACs and those on vitamin K antagonists (VKA)...
March 12, 2018: Kardiologia Polska
Patrycja Pruszkowska, Radosław Lenarczyk, Jakub Gumprecht, Ewa Jedrzejczyk-Patej, Michał Mazurek, Oskar Kowalski, Adam Sokal, Tomasz Podolecki, Stanisław Morawski, Witold Streb, Katarzyna Mitręga, Zbigniew Kalarus
BACKGROUND: Pulmonary vein isolation with cryobaloon catheter ablation (CCB) is an effective method oftreatment in patients with atrial fibrillation (AF) but in patients with heart failure (HF) therole of CCB remains unknown. AIMS: To assess feasibility, effectiveness and safety of CCB in patients with HF and cardiac electronic devices (CIED), the impact of the procedure on symptoms and echocardiographic parameters. METHODS: Thirty consecutive HF patients with left ventricular ejection fraction (EF)≤40% and CIED, referred for CCB of AF were included...
March 12, 2018: Kardiologia Polska
Jacek Migaj, Marta Kałużna-Oleksy, Jadwiga Nessler, Grzegorz Opolski, Marisa Crespo-Leiro, Aldo P Maggioni, Stefan Grajek, Piotr Ponikowski, Jarosław Drożdż, Ewa Straburzyńska-Migaj
BACKGROUND: Digoxin is used in treatment of atrial fibrillation and heart failure (HF). It was reported to increase the risk of death in HF. Studies of digoxin base mainly on patients treated some years ago, before the era of common beta-blocker use. AIM: This study aims to show the influence of digoxin in a modern cohort of HF patients on top of the contemporary guideline-directed treatment. METHODS: This study analyzes retrospectively the Polish portion of the ESC HF Long-Term Registry...
February 24, 2018: Kardiologia Polska
Olga Jelonek, Iwona Gorczyca, Michał Bączek, Paweł Kośmider, Beata Wożakowska-Kapłon
BACKGROUND: Prevention of thromboembolic complications is a priority in patients with atrial fibrillation (AF). The use of non-vitamin K antagonist oral anticoagulants (novel oral anticoagulants, NOAC) is more common, and some patients have indications for a reduced dose of NOAC. AIM: The aim of the study was to evaluate the frequency of NOACs being prescribed to AF patients and to compare the groups of AF patients receiving standard and reduced doses of NOACs. METHODS: The study was conducted in a population of 1,327 patients diagnosed with AF and hospitalized at an institution of the highest referral level in cardiology in years 2015-2016...
February 14, 2018: Kardiologia Polska
Han Jin, Shengwen Yang, Wei Hua, Min Gu, Hongxia Niu, Ligang Ding, Jing Wang, Cong Xue, Shu Zhang
BACKGROUND: Cardiac resynchronization therapy (CRT) has been shown to reduce Functional mitral regurgitation (FMR), although the relationship between significant mitral regurgitation (SMR) and the clinical prognosis of CRT remains uncertain. AIM: To investigate the association of baseline of SMR with long-term outcomes in patients undergoing CRT. METHODS: A total of 296 consecutive patients undergoing CRT were enrolled. SMR was quantified by color Doppler in all the patients at baseline and defined as grading scale ≥ 3...
February 5, 2018: Kardiologia Polska
Omer Yiginer, Mehmet Dogan, Ismet Gun, Huseyin Tayfun Kutlu, Gokhan Degirmencioglu, İlkin Guliyev, Alptug Tokatli, Fethi Kilicaslan
BACKGROUND: The frequency of arrhythmic death developing without a structural cardiac disease is higher in women. Also female gender is an independent risk factor regarding developing Torsades des Pointes. Several studies have been conducted on the effects of physiological and therapeutic sex hormones on cardiac conduction system. AIM: In this study we aim to examine the effect of hormonal changes occurring during in vitro fertilization treatment and especially supraphysiological E2 levels on ventricular repolarization parameters...
February 5, 2018: Kardiologia Polska
Ireneusz Haponiuk, Radosław Jaworski, Konrad Paczkowski, Maciej Chojnicki, Mariusz Steffens, Aneta Szofer-Sendrowska, Katarzyna Gierat-Haponiuk, Ewelina Kwaśniak, Marta Paśko-Majewska, Katarzyna Leszczyńska, Jacek Zieliński, Wiktor Szymanowicz
BACKGROUND: The extracorporeal circulation is associated with systemic inflammatory response syndrome. Therefore, the diagnosis of infection should be differenced from typical postoperative course. AIM: Evaluation of kinetics of inflammatory biomarkers in children in the first days after cardiac surgery with extracorporeal circulation. METHODS: Prospective data collection from 51 consecutive children referred for surgical treatment [the Institution], between February 2015 and August 2015...
February 5, 2018: Kardiologia Polska
Paweł Bugajski, Krzysztof Greberski, Michał Kuzemczak, Ryszard Kalawski, Radosław Jarząbek, Tomasz Siminiak
BACKGROUND: Despite increasing number of patients after percutaneous coronary interventions requiring coronary artery bypass grafting, studies on the impact of these procedures on surgical revascularization outcomes are sparse. Furthermore, advances in cardiology require reassessment of their potential prognostic significance. AIM: We sought to assess the influence of previous percutaneous coronary interventions on coronary artery bypass grafting outcomes. METHODS: 211 consecutive patients scheduled for coronary artery bypass grafting were enrolled into this prospective study...
February 5, 2018: Kardiologia Polska
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