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American Journal of Clinical Nutrition

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https://www.readbyqxmd.com/read/28931533/inflammatory-potential-of-the-diet-and-colorectal-tumor-risk-in-persons-with-lynch-syndrome
#1
Jesca Gm Brouwer, Maureen Makama, Geertruida J van Woudenbergh, Hans Fa Vasen, Fokko M Nagengast, Jan H Kleibeuker, Ellen Kampman, Fränzel Jb van Duijnhoven
Background: Persons with Lynch syndrome (LS) have high lifetime risk of developing colorectal tumors (CRTs) because of a germline mutation in one of their mismatch repair (MMR) genes. An important process in the development of CRTs is inflammation, which has been shown to be modulated by diet.Objective: We aimed to investigate the association between the inflammatory potential of the diet and the risk of CRTs in persons with LS.Design: We used the dietary intake of 457 persons with LS from a prospective cohort study to calculate the adapted dietary inflammatory index (ADII)...
September 20, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28931532/genetic-variation-of-habitual-coffee-consumption-and-glycemic-changes-in-response-to-weight-loss-diet-intervention-the-preventing-overweight-using-novel-dietary-strategies-pounds-lost-trial
#2
Liyuan Han, Wenjie Ma, Dianjianyi Sun, Yoriko Heianza, Tiange Wang, Yan Zheng, Tao Huang, Donghui Duan, J George A Bray, Catherine M Champagne, Frank M Sacks, Lu Qi
Background: Coffee consumption has been associated with glucose metabolism and risk of type 2 diabetes.Objective: We examined whether the genetic variation determining habitual coffee consumption affected glycemic changes in response to weight-loss dietary intervention.Design: A genetic risk score (GRS) was calculated based on 8 habitual coffee consumption-associated single nucleotide polymorphisms. We used general linear models to test changes in glycemic traits in groups randomly assigned to high- and low-fat diets according to tertiles of the GRS...
September 20, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28903960/biomarkers-of-food-intake-and-nutrient-status-are-associated-with-glucose-tolerance-status-and-development-of-type-2-diabetes-in-older-swedish-women
#3
Otto Savolainen, Mads Vendelbo Lind, Göran Bergström, Björn Fagerberg, Ann-Sofie Sandberg, Alastair Ross
Background: Diet is frequently associated with both the development and prevention of type 2 diabetes (T2D), but there is a lack of objective tools for assessing the relation between diet and T2D. Biomarkers of dietary intake are unconfounded by recall and reporting bias, and using multiple dietary biomarkers could help strengthen the link between a healthy diet and the prevention of T2D.Objective: The objective of this study was to explore how diet is related to glucose tolerance status (GTS) and to future development of T2D irrespective of common T2D and cardiovascular disease risk factors by using multiple dietary biomarkers...
September 13, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28903959/effect-of-prior-meal-macronutrient-composition-on-postprandial-glycemic-responses-and-glycemic-index-and-glycemic-load-value-determinations
#4
Huicui Meng, Nirupa R Matthan, Lynne M Ausman, Alice H Lichtenstein
Background: The potential impact of prior meal composition on the postprandial glycemic response and glycemic index (GI) and glycemic load (GL) value determinations remains unclear.Objective: We determined the effect of meals that varied in macronutrient composition on the glycemic response and determination of GI and GL values of a subsequent standard test food.Design: Twenty healthy participants underwent 6 test sessions within 12 wk. The subjects received each of 3 isocaloric breakfast meals (i.e., high carbohydrate, high fat, or high protein) on separate days in a random order, which was followed by a standard set of challenges (i...
September 13, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28903958/can-changes-in-the-plasma-lipidome-help-explain-the-cardiovascular-benefits-of-the-mediterranean-diet
#5
Archna Bajaj, Daniel J Rader
No abstract text is available yet for this article.
September 13, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28903957/within-day-protein-distribution-does-not-influence-body-composition-responses-during-weight-loss-in-resistance-training-adults-who-are-overweight
#6
Joshua L Hudson, Jung Eun Kim, Douglas Paddon-Jones, Wayne W Campbell
Background: Emerging research suggests that redistributing total protein intake from 1 high-protein meal/d to multiple moderately high-protein meals improves 24-h muscle protein synthesis. Over time, this may promote positive changes in body composition.Objective: We sought to assess the effects of within-day protein intake distribution on changes in body composition during dietary energy restriction and resistance training.Design: In a randomized parallel-design study, 41 men and women [mean ± SEM age: 35 ± 2 y; body mass index (in kg/m(2)): 31...
September 13, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28903956/closer-to-clarity-on-the-effect-of-lipid-consumption-on-fat-soluble-vitamin-and-carotenoid-absorption-do-we-need-to-close-in-further
#7
Nancy E Moran, Elizabeth J Johnson
No abstract text is available yet for this article.
September 13, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28903955/in-the-elderly-meat-protein-assimilation-from-rare-meat-is-lower-than-that-from-meat-that-is-well-done
#8
Caroline Buffière, Claire Gaudichon, Noureddine Hafnaoui, Carole Migné, Valérie Scislowsky, Nadezda Khodorova, Laurent Mosoni, Adeline Blot, Yves Boirie, Dominique Dardevet, Véronique Santé-Lhoutellier, Didier Rémond
Background: Meat cooking conditions in in vitro and in vivo models have been shown to influence the rate of protein digestion, which is known to affect postprandial protein metabolism in the elderly.Objectives: The present study was conducted to demonstrate the effect of cooking conditions on meat protein assimilation in the elderly. We used a single-meal protocol to assess the meat protein absorption rate and estimate postprandial meat protein utilization in elderly subjects.Design: The study recruited 10 elderly volunteers aged 70-82 y...
September 13, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28903954/quantity-and-source-of-dietary-protein-influence-metabolite-production-by-gut-microbiota-and-rectal-mucosa-gene-expression-a-randomized-parallel-double-blind-trial-in-overweight-humans
#9
Martin Beaumont, Kevin Joseph Portune, Nils Steuer, Annaïg Lan, Victor Cerrudo, Marc Audebert, Florent Dumont, Giulia Mancano, Nadezda Khodorova, Mireille Andriamihaja, Gheorghe Airinei, Daniel Tomé, Robert Benamouzig, Anne-Marie Davila, Sandrine Paule Claus, Yolanda Sanz, François Blachier
Background: Although high-protein diets (HPDs) are frequently consumed for body-weight control, little is known about the consequences for gut microbiota composition and metabolic activity and for large intestine mucosal homeostasis. Moreover, the effects of HPDs according to the source of protein need to be considered in this context.Objective: The objective of this study was to evaluate the effects of the quantity and source of dietary protein on microbiota composition, bacterial metabolite production, and consequences for the large intestinal mucosa in humans...
September 13, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28877896/intake-of-potassium-and-magnesium-enriched-salt-improves-functional-outcome-after-stroke-a-randomized-multicenter-double-blind-controlled-trial
#10
Wen-Harn Pan, Ying-Ho Lai, Wen-Ting Yeh, Jiunn-Rong Chen, Jiann-Shing Jeng, Chyi-Huey Bai, Ruey-Tay Lin, Tsong-Hai Lee, Ku-Chou Chang, Huey-Juan Lin, Chin-Fu Hsiao, Chang-Ming Chern, Li-Ming Lien, Chung-Hsiang Liu, Wei-Hung Chen, Anna Chang
Background: Stroke is one of the leading causes of mortality and neurologic deficits. Management measures to improve neurologic outcomes are in great need. Our previous intervention trial in elderly subjects successfully used salt as a carrier for potassium, demonstrating a 41% reduction in cardiovascular mortality by switching to potassium-enriched salt. Dietary magnesium has been associated with lowered diabetes and/or stroke risk in humans and with neuroprotection in animals.Objective: Because a large proportion of Taiwanese individuals are in marginal deficiency states for potassium and for magnesium and salt is a good carrier for minerals, it is justifiable to study whether further enriching salt with magnesium at an amount near the Dietary Reference Intake (DRI) amount may provide additional benefit for stroke recovery...
September 6, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28877895/trajectories-of-maternal-weight-from-before-pregnancy-through-postpartum-and-associations-with-childhood-obesity
#11
Stephanie A Leonard, Kathleen M Rasmussen, Janet C King, Barbara Abrams
Background: Prepregnancy body mass index [BMI (in kg/m(2))], gestational weight gain, and postpartum weight retention may have distinct effects on the development of child obesity, but their combined effect is currently unknown.Objective: We described longitudinal trajectories of maternal weight from before pregnancy through the postpartum period and assessed the relations between maternal weight trajectories and offspring obesity in childhood.Design: We analyzed data from 4436 pairs of mothers and their children in the National Longitudinal Survey of Youth 1979 (1981-2014)...
September 6, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28877894/later-circadian-timing-of-food-intake-is-associated-with-increased-body-fat
#12
Andrew W McHill, Andrew Jk Phillips, Charles A Czeisler, Leigh Keating, Karen Yee, Laura K Barger, Marta Garaulet, Frank Ajl Scheer, Elizabeth B Klerman
Background: Weight gain and obesity have reached alarming levels. Eating at a later clock hour is a newly described risk factor for adverse metabolic health; yet, how eating at a later circadian time influences body composition is unknown. Using clock hour to document eating times may be misleading owing to individual differences in circadian timing relative to clock hour.Objective: This study examined the relations between the timing of food consumption relative to clock hour and endogenous circadian time, content of food intake, and body composition...
September 6, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28877893/randomized-controlled-trial-on-the-impact-of-early-life-intervention-with-bifidobacteria-on-the-healthy-infant-fecal-microbiota-and-metabolome
#13
Monika Bazanella, Tanja V Maier, Thomas Clavel, Ilias Lagkouvardos, Marianna Lucio, Maria X Maldonado-Gòmez, Chloe Autran, Jens Walter, Lars Bode, Philippe Schmitt-Kopplin, Dirk Haller
Background: Early-life colonization of the intestinal tract is a dynamic process influenced by numerous factors. The impact of probiotic-supplemented infant formula on the composition and function of the infant gut microbiota is not well defined.Objective: We sought to determine the effects of a bifidobacteria-containing formula on the healthy human intestinal microbiome during the first year of life.Design: A double-blind, randomized, placebo-controlled study of newborn infants assigned to a standard whey-based formula containing a total of 10(8) colony-forming units (CFU)/g of Bifidobacterium bifidum, Bifidobacterium breve, Bifidobacterium longum, B...
September 6, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28877892/supplementing-a-normal-diet-with-protein-yields-a-moderate-improvement-in-the-robust-gains-in-muscle-mass-and-strength-induced-by-resistance-training-in-older-individuals
#14
Lars Holm, Nikolai B Nordsborg
No abstract text is available yet for this article.
September 6, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28877891/investigating-predictors-of-eating-is-resting-metabolic-rate-really-the-strongest-proxy-of-energy-intake
#15
Jessica McNeil, Gilles Lamothe, Jameason D Cameron, Marie-Ève Riou, Sébastien Cadieux, Jacynthe Lafrenière, Gary Goldfield, Stephanie Willbond, Denis Prud'homme, Éric Doucet
Background: Evidence suggests that fat-free mass and resting metabolic rate (RMR), but not fat mass, are strong predictors of energy intake (EI). However, body composition and RMR do not explain the entire variance in EI, suggesting that other factors may contribute to this variance.Objective: We aimed to investigate the associations between body mass index (in kg/m(2)), fat mass, fat-free mass, and RMR with acute (1 meal) and daily (24-h) EI and between fasting appetite ratings and certain eating behavior traits with daily EI...
September 6, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28877890/tackling-iron-deficiency-in-infants-galacto-oligosaccharides-may-be-up-to-the-task
#16
Fudi Wang
No abstract text is available yet for this article.
September 6, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28855225/plasma-glucose-and-insulin-responses-after-consumption-of-breakfasts-with-different-sources-of-soluble-fiber-in-type-2-diabetes-patients-a-randomized-crossover-clinical-trial
#17
Cláudia M de Carvalho, Tatiana P de Paula, Luciana V Viana, Vitória Mt Machado, Jussara C de Almeida, Mirela J Azevedo
Background: The amount and quality of carbohydrates are important determinants of plasma glucose after meals. Regarding fiber content, it is unclear whether the intake of soluble fibers from foods or supplements has an equally beneficial effect on lowering postprandial glucose.Objective: The aim of our study was to compare the acute effect of soluble fiber intake from foods or supplements after a common meal on postprandial plasma glucose and plasma insulin in patients with type 2 diabetes (T2D).Design: A randomized crossover clinical trial was conducted in patients with T2D...
August 30, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28855224/dha-rich-n-3-fatty-acid-supplementation-decreases-dna-methylation-in-blood-leukocytes-the-omegad-study
#18
Mohsen Karimi, Inger Vedin, Yvonne Freund Levi, Hans Basun, Gerd Faxén Irving, Maria Eriksdotter, Lars-Olof Wahlund, Marianne Schultzberg, Erik Hjorth, Tommy Cederholm, Jan Palmblad
Background: Dietary fish oils, rich in long-chain n-3 (ω-3) fatty acids (FAs) [e.g., docosahexaenoic acid (DHA, 22:6n-3) and eicosapentaenoic acid (EPA, 20:5n-3)], modulate inflammatory reactions through various mechanisms, including gene expression, which is measured as messenger RNA concentration. However, the effects of long-term treatment of humans with DHA and EPA on various epigenetic factors-such as DNA methylation, which controls messenger RNA generation-are poorly described.Objective: We wanted to determine the effects of 6 mo of dietary supplementation with an n-3 FA preparation rich in DHA on global DNA methylation of peripheral blood leukocytes (PBLs) and the relation to plasma EPA and DHA concentrations in Alzheimer disease (AD) patients...
August 30, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28855223/effects-of-dietary-sodium-on-metabolites-the-dietary-approaches-to-stop-hypertension-dash-sodium-feeding-study
#19
Andriy Derkach, Joshua Sampson, Justin Joseph, Mary C Playdon, Rachael Z Stolzenberg-Solomon
Background: High sodium intake is known to increase blood pressure and is difficult to measure in epidemiologic studies.Objective: We examined the effect of sodium intake on metabolites within the DASH (Dietary Approaches to Stop Hypertension Trial)-Sodium Trial to further our understanding of the biological effects of sodium intake beyond blood pressure.Design: The DASH-Sodium Trial randomly assigned individuals to either the DASH diet (low in fat and high in protein, low-fat dairy, and fruits and vegetables) or a control diet for 12 wk...
August 30, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28835366/vitamin-d-prenatal-programming-of-childhood-metabolomics-profiles-at-age-3-y
#20
Kevin Blighe, Bo L Chawes, Rachel S Kelly, Hooman Mirzakhani, Michael McGeachie, Augusto A Litonjua, Scott T Weiss, Jessica A Lasky-Su
Background: Vitamin D deficiency is implicated in a range of common complex diseases that may be prevented by gestational vitamin D repletion. Understanding the metabolic mechanisms related to in utero vitamin D exposure may therefore shed light on complex disease susceptibility.Objective: The goal was to analyze the programming role of in utero vitamin D exposure on children's metabolomics profiles.Design: First, unsupervised clustering was done with plasma metabolomics profiles from a case-control subset of 245 children aged 3 y with and without asthma from the Vitamin D Antenatal Asthma Reduction Trial (VDAART), in which pregnant women were randomly assigned to vitamin D supplementation or placebo...
August 23, 2017: American Journal of Clinical Nutrition
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