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American Journal of Clinical Nutrition

Ai-Ru Chia, Jamie V de Seymour, Marjorelee Colega, Ling-Wei Chen, Yiong-Huak Chan, Izzuddin M Aris, Mya-Thway Tint, Phaik Ling Quah, Keith M Godfrey, Fabian Yap, Seang-Mei Saw, Philip N Baker, Yap-Seng Chong, Rob M van Dam, Yung Seng Lee, Mary Foong-Fong Chong
BACKGROUND: Maternal dietary patterns during pregnancy have been shown to influence infant birth outcomes. However, to our knowledge, only a few studies have examined the associations in Asian populations. OBJECTIVE: We characterized maternal dietary patterns in Asian pregnant women and examined their associations with the risk of preterm birth and offspring birth size. DESIGN: At 26-28 wk of gestation, 24-h recalls and 3-d food diaries were collected from the women in the Growing Up in Singapore Towards healthy Outcomes mother-offspring cohort...
October 12, 2016: American Journal of Clinical Nutrition
Patsy M Brannon, Connie M Weaver, Cheryl Am Anderson, Sharon M Donovan, Suzanne P Murphy, Ann L Yaktine
BACKGROUND: Dietary Reference Intakes (DRIs) are fundamental to inform national nutrition policy. However, a regular systematic review of the 51 nutrients that have DRIs has limited feasibility, and many DRIs have not been reviewed in >15 y. OBJECTIVE: To address this issue, individuals (nutrient review group) who were members of the Food and Nutrition Board developed a streamlined, evidence-based methodology that could be used to identify nutrients potentially in need of a systematic review...
October 12, 2016: American Journal of Clinical Nutrition
Eva Pedersen, Kylie Lange, Peter Clifton
BACKGROUND: People with type 2 diabetes are advised to consume an even meal distribution of carbohydrate. Whether this distribution is optimal is unknown. OBJECTIVE: Our objective was to show that omitting carbohydrate in the first meal after a fast would lead to an augmented lunch response. DESIGN: Two diets of 1-d duration that differed only in the breakfast-meal composition (carbohydrate or no carbohydrate) were consumed on sequential days in a randomized crossover study...
October 12, 2016: American Journal of Clinical Nutrition
Raquel de Deus Mendonça, Adriano Marçal Pimenta, Alfredo Gea, Carmen de la Fuente-Arrillaga, Miguel Angel Martinez-Gonzalez, Aline Cristine Souza Lopes, Maira Bes-Rastrollo
BACKGROUND: Ultraprocessed food consumption has increased in the past decade. Evidence suggests a positive association between ultraprocessed food consumption and the incidence of overweight and obesity. However, few prospective studies to our knowledge have investigated this potential relation in adults. OBJECTIVE: We evaluated the association between ultraprocessed food consumption and the risk of overweight and obesity in a prospective Spanish cohort, the SUN (University of Navarra Follow-Up) study...
October 12, 2016: American Journal of Clinical Nutrition
Charlotte Mortensen, Camilla T Damsgaard, Hanne Hauger, Christian Ritz, Susan A Lanham-New, Taryn J Smith, Áine Hennessy, Kirsten Dowling, Kevin D Cashman, Mairead Kiely, Christian Mølgaard
BACKGROUND: Children in northern latitudes are at high risk of vitamin D deficiency during winter because of negligible dermal vitamin D3 production. However, to our knowledge, the dietary requirement for maintaining the nutritional adequacy of vitamin D in young children has not been investigated. OBJECTIVE: We aimed to establish the distribution of vitamin D intakes required to maintain winter serum 25-hydroxyvitamin D [25(OH)D] concentrations above the proposed cutoffs (25, 30, 40, and 50 nmol/L) in white Danish children aged 4-8 y living at 55°N...
October 12, 2016: American Journal of Clinical Nutrition
Jordi Mayneris-Perxachs, David T Bolick, Joy Leng, Greg L Medlock, Glynis L Kolling, Jason A Papin, Jonathan R Swann, Richard L Guerrant
BACKGROUND: Environmental enteropathy, which is linked to undernutrition and chronic infections, affects the physical and mental growth of children in developing areas worldwide. Key to understanding how these factors combine to shape developmental outcomes is to first understand the effects of nutritional deficiencies on the mammalian system including the effect on the gut microbiota. OBJECTIVE: We dissected the nutritional components of environmental enteropathy by analyzing the specific metabolic and gut-microbiota changes that occur in weaned-mouse models of zinc or protein deficiency compared with well-nourished controls...
October 12, 2016: American Journal of Clinical Nutrition
Karin Schindler, Michael Themessl-Huber, Michael Hiesmayr, Sigrid Kosak, Mitja Lainscak, Alessandro Laviano, Olle Ljungqvist, Mohamed Mouhieddine, Stéphane Schneider, Marian de van der Schueren, Tatjana Schütz, Christian Schuh, Pierre Singer, Peter Bauer, Claude Pichard
BACKGROUND: Inadequate nutrition during hospitalization is strongly associated with poor patient outcome, but ensuring adequate food intake is not a priority in clinical routine worldwide. This lack of priority results in inadequate and unbalanced food intake in patients and huge amounts of wasted food. OBJECTIVES: We evaluate the main factors that are associated with reduced meal intake in hospitalized patients and the differences between geographical regions. DESIGN: We conducted a descriptive analysis of data from 9 consecutive, annual, and cross-sectional nutritionDay samples (2006-2014) in a total of 91,245 adult patients in 6668 wards in 2584 hospitals in 56 countries...
October 12, 2016: American Journal of Clinical Nutrition
Danxia Yu, Xianglan Zhang, Xiao-Ou Shu, Hui Cai, Honglan Li, Ding Ding, Zhen Hong, Yong-Bing Xiang, Yu-Tang Gao, Wei Zheng, Gong Yang
BACKGROUND: Epidemiologic evidence on dietary carbohydrates and stroke risk remains controversial. Very few prospective cohort studies have been conducted in Asian populations, who usually consume a high-carbohydrate diet and have a high burden of stroke. OBJECTIVE: We examined dietary glycemic index (GI), glycemic load (GL), and intakes of refined and total carbohydrates in relation to risks of total, ischemic, and hemorrhagic stroke and stroke mortality. DESIGN: This study included 64,328 Chinese women, aged 40-70 y, with no history of cardiovascular disease, diabetes, or cancer...
October 12, 2016: American Journal of Clinical Nutrition
Eugene Kobyliansky, Dmitry Torchinsky, Leonid Kalichman, David Karasik
BACKGROUND: To our knowledge, there are no experimental studies that have addressed the effects of starvation on the maintenance of telomere length. Two epidemiologic studies that have addressed this topic gave controversial results. OBJECTIVE: We characterized leukocyte telomere length (LTL) in a Chuvash population that was comprised of survivors of the mass famine of 1922-1923 and in these survivors' descendants. DESIGN: The tested cohort consisted of native Chuvash men (n = 687) and women (n = 647) who were born between 1909 and 1980 and who resided in small villages in the Chuvash Republic of the Russian Federation...
October 12, 2016: American Journal of Clinical Nutrition
Ameneh Madjd, Moira A Taylor, Leila Shafiei Neek, Alireza Delavari, Reza Malekzadeh, Ian A Macdonald, Hamid R Farshchi
BACKGROUND: The effect of intensity and duration of physical activity (PA) on weight loss has been well described. However, the effect of the frequency of weekly PA on weight loss is still unknown. OBJECTIVE: The purpose of this study was to evaluate the effect of the frequency of weekly PA sessions while maintaining the same total activity time on weight loss during a 24-wk weight loss program. DESIGN: Overweight and obese women [n = 75; body mass index (BMI; in kg/m(2)): 27-37; age: 18-40 y] who had a normally sedentary lifestyle were randomly allocated to 1 of 2 intervention groups: a high-frequency physical activity (HF) or a low-frequency physical activity (LF) group...
October 12, 2016: American Journal of Clinical Nutrition
Bradley C Johnston, Gordon H Guyatt
Among clinical trials of adequate size, randomization balances both known and unknown prognostic factors between trial arms, thus allowing an unbiased comparison of intervention and control. To preserve this benefit, all randomly assigned participants should be followed to study termination and analyzed in the arm to which they were allocated. There are 2 potential limitations in study implementation: 1) patients are nonadherent and continue with follow-up visits, or 2) patients are lost to follow-up and their outcome data are missing...
October 12, 2016: American Journal of Clinical Nutrition
Raschida R Bouhouch, Sana El-Fadeli, Maria Andersson, Abdelmounaim Aboussad, Laila Chabaa, Christophe Zeder, Maria Kippler, Jeannine Baumgartner, Azzedine Sedki, Michael B Zimmermann
BACKGROUND: Lead is a common neurotoxicant and its absorption may be increased in iron deficiency (ID). Thus, iron fortification to prevent ID in populations is a promising lead mitigation strategy. Two common fortificants are ferrous sulfate (FeSO4) and ferric sodium EDTA (NaFeEDTA). EDTA can chelate iron and lead. OBJECTIVES: Our study objective was to determine the effects of iron and EDTA, alone and in combination, on blood lead (BPb) concentration, iron status, and cognition...
October 12, 2016: American Journal of Clinical Nutrition
Dennis M Bier, Walter C Willett
No abstract text is available yet for this article.
October 12, 2016: American Journal of Clinical Nutrition
Shu-Chun Chuang, Hui-Ling Chen, Wei-Ting Tseng, I-Chien Wu, Chih-Cheng Hsu, Hsing-Yi Chang, Yii-Der Ida Chen, Marion M Lee, Kiang Liu, Chao Agnes Hsiung
BACKGROUND: A previous study indicated that 31% of the elderly in Taiwan have a vitamin D deficiency. Vitamin D adequacy has been associated with physical performance in the elderly. OBJECTIVES: The first aim of the current study was to identify the determinants for vitamin D deficiency. The second aim was to evaluate the association between vitamin D status and physical performance. DESIGN: A total of 5664 community-dwelling participants aged ≥55 y were recruited since 2008...
October 12, 2016: American Journal of Clinical Nutrition
Steven A Abrams
No abstract text is available yet for this article.
October 12, 2016: American Journal of Clinical Nutrition
Hathairat Sawaengsri, Peter R Bergethon, Wei Qiao Qiu, Tammy M Scott, Paul F Jacques, Jacob Selhub, Ligi Paul
BACKGROUND: The 776C→G polymorphism of the vitamin B-12 transport protein transcobalamin gene (TCN2) (rs1801198; Pro259Arg) is associated with a lower holotranscobalamin concentration in plasma. This effect may reduce the availability of vitamin B-12 to tissues even when vitamin B-12 intake is adequate. Clinical outcomes associated with vitamin B-12 insufficiency could potentially be worsened by high folate intake. OBJECTIVE: We determined the association of the TCN2 776C→G polymorphism and folate intake with peripheral neuropathy in elders with normal plasma concentrations of vitamin B-12...
October 12, 2016: American Journal of Clinical Nutrition
Ping Li, Chaonan Fan, Yuanyuan Lu, Kemin Qi
BACKGROUND: Whether calcium supplementation can reduce body weight and prevent obesity remains unclear because of inconsistent reports. OBJECTIVE: We performed a meta-analysis to investigate the correlations between calcium supplementation and changes in body weight on the basis of age, sex, body mass index (BMI) of the subjects, and length of calcium intervention. DESIGN: PubMed, EMBASE, Web of Knowledge, and China National Knowledge Infrastructure databases were systematically searched to select relevant studies that were published from January 1994 to March 2016...
October 12, 2016: American Journal of Clinical Nutrition
D Ian Givens, Sabita S Soedamah-Muthu
No abstract text is available yet for this article.
October 12, 2016: American Journal of Clinical Nutrition
Charles E Matthews, Sarah Kozey Keadle, Richard P Troiano, Lisa Kahle, Annemarie Koster, Robert Brychta, Dane Van Domelen, Paolo Caserotti, Kong Y Chen, Tamara B Harris, David Berrigan
BACKGROUND: Moderate-to-vigorous-intensity physical activity is recommended to maintain and improve health, but the mortality benefits of light activity and risk for sedentary time remain uncertain. OBJECTIVES: Using accelerometer-based measures, we 1) described the mortality dose-response for sedentary time and light- and moderate-to-vigorous-intensity activity using restricted cubic splines, and 2) estimated the mortality benefits associated with replacing sedentary time with physical activity, accounting for total activity...
October 5, 2016: American Journal of Clinical Nutrition
Karen E Christensen, Wenyang Hou, Renata H Bahous, Liyuan Deng, Olga V Malysheva, Erland Arning, Teodoro Bottiglieri, Marie A Caudill, Loydie A Jerome-Majewska, Rima Rozen
BACKGROUND: Moderately high folic acid intake in pregnant women has led to concerns about deleterious effects on the mother and fetus. Common polymorphisms in folate genes, such as methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase-formyltetrahydrofolate synthetase (MTHFD1) R653Q, may modulate the effects of elevated folic acid intake. OBJECTIVES: We investigated the effects of moderate folic acid supplementation on reproductive outcomes and assessed the potential interaction of the supplemented diet with MTHFD1-synthetase (Mthfd1S) deficiency in mice, which is a model for the R653Q variant...
October 5, 2016: American Journal of Clinical Nutrition
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