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Age and Ageing

Mandip S Dhamoon, Ying-Kuen Cheung, Yeseon P Moon, Clinton B Wright, Joshua Z Willey, Ralph Sacco, Mitchell Sv Elkind
BACKGROUND: high-sensitivity C-reactive protein (CRP) has been associated with cardiovascular events and mortality, but the association of CRP with functional status is not well defined. We hypothesised that serum levels of high-sensitivity CRP are associated with long-term trajectories of functional status independently of vascular risk factors and stroke and myocardial infarction (MI) occurring during follow-up. DESIGN: prospective, population-based. SETTING: northern Manhattan Study...
October 15, 2016: Age and Ageing
Jennifer Kirsty Harrison, Azucena Garcia Garrido, Sarah J Rhynas, Gemma Logan, Alasdair M J MacLullich, Juliet MacArthur, Susan Shenkin
BACKGROUND: institutionalisation following acute hospital admission is common and yet poorly described, with policy documents advising against this transition. OBJECTIVE: to characterise the individuals admitted to a care home on discharge from an acute hospital admission and to describe their assessment. DESIGN AND SETTING: a retrospective cohort study of people admitted to a single large Scottish teaching hospital. SUBJECTS: 100 individuals admitted to the acute hospital from home and discharged to a care home...
October 15, 2016: Age and Ageing
Shota Hamada, Martin C Gulliford
OBJECTIVE: to evaluate primary care drug utilisation during the last year of life, focusing on antidiabetic and cardiovascular drugs, in patients of advanced age with diabetes. DESIGN: population-based cohort study. SETTING: primary care database in the UK. SUBJECTS: patients with type 2 diabetes who died at over 80 years of age between 2011 and 13. METHODS: main outcome measures included proportions of patients prescribed different classes of drugs, comparing the first (Q1) and the fourth quarters (Q4) of the last year of life...
October 15, 2016: Age and Ageing
David Barer
BACKGROUND: an increased mortality rate among patients admitted to hospital at weekends has been found in many studies, and this 'weekend effect' has been used to justify major health service reorganisation. Most studies have used routine administrative data to adjust for potential confounding factors, and are unable to measure differences in illness severity due to the tendency of patients with milder symptoms to stay home at weekends. We set out to estimate the importance of such unmeasured 'confounding by severity', using data from a hospital stroke register...
October 15, 2016: Age and Ageing
Qu Tian, Yang An, Susan M Resnick, Stephanie Studenski
BACKGROUND: most older individuals who experience mobility decline, also show cognitive decline, but whether cognitive decline precedes or follows mobility limitation is not well understood. OBJECTIVE: examine the temporal sequence of mobility and cognition among initially unimpaired older adults. METHODS: mobility and cognition were assessed every 2 years for 6 years in 412 participants aged ≥60 with initially unimpaired cognition and gait speed...
October 15, 2016: Age and Ageing
Ilse Bloom, Mark Edwards, Karen A Jameson, Holly E Syddall, Elaine Dennison, Catharine R Gale, Janis Baird, Cyrus Cooper, Avan Aihie Sayer, Sian Robinson
BACKGROUND: poor diet quality is common among older people, but little is known about influences on food choice, including the role of psychosocial factors at this age. OBJECTIVE: to identify psychosocial correlates of diet quality in a community-dwelling population of men and women aged 59-73 years; to describe relationships with change in diet quality over 10 years. DESIGN: Longitudinal cohort, Hertfordshire Cohort Study (HCS). SUBJECTS: HCS participants assessed at baseline (1998-2003: 1,048 men, 862 women); 183 men and 189 women re-assessed in 2011...
October 15, 2016: Age and Ageing
Fiona Clague, Stewart W Mercer, Gary McLean, Emma Reynish, Bruce Guthrie
BACKGROUND: the care of older people with dementia is often complicated by physical comorbidity and polypharmacy, but the extent and patterns of these have not been well described. This paper reports analysis of these factors within a large, cross-sectional primary care data set. METHODS: data were extracted for 291,169 people aged 65 years or older registered with 314 general practices in the UK, of whom 10,258 had an electronically recorded dementia diagnosis...
October 13, 2016: Age and Ageing
Philip Robert Baker, Daniel Peter Francis, Noran Naqiah Mohd Hairi, Sajaratulnisah Othman, Wan Yuen Choo
There is evidence that elder abuse is a significant public health problem that is destined to grow as population age. Countries are considering how best to act and this requires an understanding of the complex causal mechanisms contributing to its occurrence and the identification of effective interventions which can potentially make a difference. Previously, a high quality synthesis of evidence for policy and practice has been missing. In this paper, we describe a new Cochrane review of interventions to prevent the occurrence or reoccurrence of elder abuse...
October 13, 2016: Age and Ageing
Claire Goodman
No abstract text is available yet for this article.
October 13, 2016: Age and Ageing
Jim E Banta
No abstract text is available yet for this article.
October 13, 2016: Age and Ageing
Guy Hindley, John Kissima, Lloyd L Oates, Stella-Maria Paddick, Aloyce Kisoli, Christine Brandsma, William K Gray, Richard W Walker, Declare Mushi, Catherine L Dotchin
BACKGROUND: low diagnostic rates are a barrier to improving care for the growing number of people with dementia in sub-Saharan Africa. Many people with dementia are thought to visit traditional healers (THs) and Christian faith healers (FHs) and these groups may have a role in identifying people with dementia. We aimed to explore the practice and attitudes of these healers regarding dementia in rural Tanzania and investigate attitudes of their patients and their patients' carers. METHODS: this was a qualitative study conducted in Hai district, Tanzania...
October 4, 2016: Age and Ageing
Patricia López Pardo, Concepción Jiménez Rojas, María Moral Carretón
Although neuromyelitis optica initially described by Eugen Devic in 1897 was considered for many years as a variant of multiple sclerosis, clinical course, more aggressive from the start, progressive towards severe disability and poor visual prognosis, and a different response to treatment, clearly point to a different process. Anti-aquaporin 4 antibodies are a specific biomarker of the entity and, since their discovery, both the number of symptoms and the radiological data about the disease have progressively increased, and the concept of clinical spectrum of neuromyelitis optica has been defined...
September 13, 2016: Age and Ageing
Judy Lowthian
No abstract text is available yet for this article.
September 13, 2016: Age and Ageing
Blanca Serrano Falcón, Ángel Álvarez Sánchez, Manuel Diaz-Rubio, Enrique Rey
BACKGROUND: faecal impaction (FI) is a common problem in old people living in nursing home. Its prevalence and associated factors remain unknown in the general population. AIM: to evaluate FI prevalence in the Spanish population older than 65 years and to assess the factors associated with it. METHODS: a telephone survey was carried out of a Spanish population older than 65 years random sample (N = 1000). FI was assessed using a previously validated questionnaire...
September 12, 2016: Age and Ageing
George J E Crowther, Michael I Bennett, John D Holmes
INTRODUCTION: in the United Kingdom dementia is generally diagnosed by mental health services. General hospitals are managed by separate healthcare trusts and the handover of clinical information between organisations is potentially unreliable. Around 40% of older people admitted to hospital have dementia. This group have a high prevalence of psychological symptoms and delirium. If the dementia diagnosis or symptoms are not recognised, patients may suffer unnecessarily with resulting negative outcomes...
September 10, 2016: Age and Ageing
Nicole D A Boyé, Nathalie van der Velde, Oscar J de Vries, Esther M M van Lieshout, Klaas A Hartholt, Francesco U S Mattace-Raso, Paul Lips, Peter Patka, Ed F van Beeck, Tischa J M van der Cammen
OBJECTIVES: to investigate the effect of withdrawal of fall-risk-increasing-drugs (FRIDs) versus 'care as usual' on reducing falls in community-dwelling older fallers. DESIGN: randomised multicentre trial. PARTICIPANTS: six hundred and twelve older adults who visited an Emergency Department (ED) because of a fall. INTERVENTIONS: withdrawal of FRIDs. MAIN OUTCOMES AND MEASURES: primary outcome was time to the first self-reported fall...
September 10, 2016: Age and Ageing
Timothy Kwok, Jason Leung, Elizabeth Barrett-Connor
INTRODUCTION: angiotensin II, a major effector protein of the renin angiotensin system (RAS), induces bone loss under certain conditions. Drugs that block the RAS may therefore reduce bone loss and fracture incidence. The fracture incidence in older hypertensive men with long-term use of angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs) were compared with the incidence in users of calcium channel blockers (CCBs) and non-users. METHODS: a total of 5,994 US men aged 65 years or older who had bone mineral density measured at baseline in the Osteoporotic Fractures in Men Study (MrOS) were followed for fracture incidence for an average of 6...
September 10, 2016: Age and Ageing
Glenn Arendts, Stephen Jan, Matthew J Beck, Kirsten Howard
OBJECTIVES: to estimate the effect of factors that influence decisions to transfer residents of aged care facilities to an emergency department (ED) for acute medical emergencies. DESIGN AND PARTICIPANTS: a discrete choice experiment with residents (N = 149), the relatives of residents (N = 137) and staff members (N = 128) of aged care facilities. SETTING: aged care facilities in three Australian states. OUTCOME MEASURES: using random parameter logit models, parameter estimates and odds ratios were estimated, and resultant utility functions for ED and alternate care were constructed...
September 10, 2016: Age and Ageing
Marjon van Rijn, Jacqueline J Suijker, Wietske Bol, Eva Hoff, Gerben Ter Riet, Sophia E de Rooij, Eric P Moll van Charante, Bianca M Buurman
OBJECTIVES: to study (i) the prevalence of geriatric conditions in community-dwelling older persons at increased risk of functional decline and (ii) the extent to which older persons recognise comprehensive geriatric assessment (CGA)-identified conditions as relevant problems. METHODS: trained registered nurses conducted a CGA in 934 out of 1209 older persons at increased risk of functional decline participating in the intervention arm of a randomised trial in the Netherlands...
September 10, 2016: Age and Ageing
Kimiko Tomioka, Norio Kurumatani, Hiroshi Hosoi
BACKGROUND: self-rated health (SRH) is a strong predictor of mortality, but it is unclear if SRH independently predicts a decline in instrumental activities of daily living (IADL). OBJECTIVE: to verify whether SRH is an independent predictor of IADL decline. DESIGN: a population-based longitudinal cohort study. SETTING: two local municipalities in Nara, Japan. SUBJECTS: community-dwelling older adults 65 years or older (2,638 males and 3,346 females) with independent IADL at baseline...
September 10, 2016: Age and Ageing
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