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Age and Ageing

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https://www.readbyqxmd.com/read/29165543/identification-of-older-adults-with-frailty-in-the-emergency-department-using-a-frailty-index-results-from-a-multinational-study
#1
Audrey-Anne Brousseau, Elsa Dent, Ruth Hubbard, Don Melady, Marcel Émond, Éric Mercier, Andrew P Costa
Objective: frailty is a central concept in geriatric medicine, yet its utility in the Emergency Department (ED) is not well understood nor well utilised. Our objectives were to develop an ED frailty index (FI-ED), using the Rockwood cumulative deficits model and to evaluate its association with adverse outcomes. Method: this was a large multinational prospective cohort study using data from the interRAI Multinational Emergency Department Study. The FI-ED was developed from the Canadian cohort and validated in the multinational cohort...
November 20, 2017: Age and Ageing
https://www.readbyqxmd.com/read/29161361/trajectories-of-frailty-among-chinese-older-people-in-hong-kong-between-2001-and-2012-an-age-period-cohort-analysis
#2
Ruby Yu, Moses Wong, K C Chong, Billy Chang, C M Lum, T W Auyeung, Jenny Lee, Ruby Lee, Jean Woo
Background: there is little evidence to suggest that older people today are living in better health than their predecessors did at the same age. Only a few studies have evaluated whether there are birth cohort effects on frailty, an indicator of health in older people, encompassing physical, functional and mental health dimensions. Objectives: this study examined longitudinal trajectories of frailty among Chinese older people in Hong Kong. Methods: this study utilised data from the 18 Elderly Health Centres of the Department of Health comprising a total of 417,949 observations from 94,550 community-dwelling Chinese people aged ≥65 years in one early birth cohort (1901-23) and four later birth cohorts (1924-29, 1930-35, 1936-41, 1942-47) collected between 2001 and 2012, to examine trajectories of the frailty index and how birth cohorts may have contributed to the trends using an age-period-cohort analysis...
November 17, 2017: Age and Ageing
https://www.readbyqxmd.com/read/29145553/tumour-boards-in-geriatric-oncology
#3
Tanya Marya Wildes, Anita O'Donovan, Giuseppe Ferdinando Colloca, Kwok-Leung Cheung
Multidisciplinary tumour board is an integral part of cancer treatment planning. Although no definite survival benefits have yet been shown by mostly observational studies, other benefits of multidisciplinary tumour board have been identified. Traditionally the multidisciplinary tumour board involves participation of treating clinicians-medical, radiation and surgical oncologists. They tend to focus on the cancer alone. There is an increasing awareness that the treatment goal for cancer in older adults is not primarily on prolonging survival, with functional preservation and quality of life being particularly important for this population...
November 14, 2017: Age and Ageing
https://www.readbyqxmd.com/read/29145548/supported-discharge-teams-for-older-people-in-hospital-acute-care-hospital-a-randomised-controlled-trial
#4
Matthew Parsons, John Parsons, Paul Rouse, Avinesh Pillai, Sean Mathieson, Rochelle Parsons, Christine Smith, Tim Kenealy
Background: Supported Discharge Teams aim to help with the transition from hospital to home, whilst reducing hospital length-of-stay. Despite their obvious attraction, the evidence remains mixed, ranging from strong support for disease-specific interventions to less favourable results for generic services. Objective: To determine whether older people referred to a Supported Discharge Team have: (i) reduced length-of-stay in hospital; (ii) reduced risk of hospital readmission; and (iii) reduced healthcare costs...
November 14, 2017: Age and Ageing
https://www.readbyqxmd.com/read/29136094/effects-of-multidomain-lifestyle-intervention-omega-3-supplementation-or-their-combination-on-physical-activity-levels-in-older-adults-secondary-analysis-of-the-multidomain-alzheimer-preventive-trial-mapt-randomised-controlled-trial
#5
Philipe de Souto Barreto, Yves Rolland, Matteo Cesari, Charlotte Dupuy, Sandrine Andrieu, Bruno Vellas
Background/objectives: to investigate the effects of a 3-year multidomain lifestyle intervention, omega-3 supplementation or both on physical activity (PA) in older adults with subjective memory complaints. Design/settings/subjects: the Multidomain Alzheimer Preventive Trial was a 3-year randomised controlled trial that enroled 1,680 community-dwelling adults aged 70 years or over, with subjective memory complaints. Participants were randomised to omega-3 supplementation (total daily dose of 800 mg docosahexanoic acid and up to 225 mg eicosapentanoic acid), multidomain intervention (nutritional and exercise counselling and cognitive training), omega-3 plus multidomain intervention or placebo with usual care...
November 10, 2017: Age and Ageing
https://www.readbyqxmd.com/read/29096004/childlessness-and-vulnerability-of-older-people-in-china
#6
Zhixin Feng
Background: the number of childless older people is increasing in China, but relatively little is known about the role of childlessness in health outcomes. This study investigates the relationship between childlessness and three health outcomes: difficulty with Instrumental Activities of Daily Living (IADLs), self-rated health and depression. Methods: this study includes 13,171 individuals aged 50 and above from national survey data of the second wave of the China Family Panel Study (2012)...
October 31, 2017: Age and Ageing
https://www.readbyqxmd.com/read/29088316/alcohol-consumption-in-midlife-and-old-age-and-risk-of-frailty-alcohol-paradox-in-a-30-year-follow-up-study
#7
Arto Y Strandberg, Teemu Trygg, Kaisu H Pitkälä, Timo E Strandberg
Background: alcohol consumption has many harmful health effects, but also benefits of moderate consumption on frailty have been reported. We examined this relationship longitudinally from midlife to old age. Methods: data of reported alcohol consumption in midlife (year 1974) and in old age (years 2000 and 2003) were available of a socioeconomically homogenous sample of 2360 men (born 1919-34, the Helsinki Businessmen Study). Alcohol consumption was divided into zero (N = 131 at baseline), light (1-98 g/week, N = 920), moderate (99-196, N = 593), and high consumption (>196, n = 716)...
October 27, 2017: Age and Ageing
https://www.readbyqxmd.com/read/29077902/z-drugs-and-risk-for-falls-and-fractures-in-older-adults-a-systematic-review-and-meta-analysis
#8
Nir Treves, Amichai Perlman, Lital Kolenberg Geron, Angham Asaly, Ilan Matok
Objective: zolpidem, zopiclone, eszopiclone and zaleplon, also known as 'Z-drugs', are commonly used as alternatives to benzodiazepines (BZDs) to treat insomnia. Z-drugs are often perceived as safer than BZDs. We conducted a systematic review and meta-analysis evaluating the association between Z-drugs and fracutres, falls and injuries. Methods: a systematic review was performed using MEDLINE, EMBASE and ClinicalTials.gov. Pooled effect-sizes were calculated comparing Z-drugs users with non-users, using fixed and random-effect models with corresponding 95% confidence of intervals (CI)...
October 25, 2017: Age and Ageing
https://www.readbyqxmd.com/read/29088331/haloperidol-for-delirium-prevention-uncertainty-remains
#9
Elizabeth Ann Teale
No abstract text is available yet for this article.
October 24, 2017: Age and Ageing
https://www.readbyqxmd.com/read/29040347/frailty-index-as-a-predictor-of-mortality-a-systematic-review-and-meta-analysis
#10
Gotaro Kojima, Steve Iliffe, Kate Walters
Background: two popular operational definitions of frailty, the frailty phenotype and Frailty index (FI), are based on different theories. Although FI was shown to be superior in predicting mortality to the frailty phenotype, no meta-analysis on mortality risk according to FI has been found in the literature. Methods: an electronic systematic literature search was conducted in August 2016 using four databases (Embase, Medline, CINAHL and PsycINFO) for prospective cohort studies published in 2000 or later, examining the mortality risk according to frailty measured by FI...
October 13, 2017: Age and Ageing
https://www.readbyqxmd.com/read/29040344/dilemmas-for-guardians-of-advanced-dementia-patients-regarding-tube-feeding
#11
Efrat Gil, Maayan Agmon, Ayal Hirsch, Miriam Ziv, Anna Zisberg
Background: advanced dementia is an incurable illness, its last stage marked by inability to eat. Tube feeding was deemed a helpful solution at this stage, but in recent years its inefficiency has been proved, and it is no longer practiced in many countries around the world. In Israel, however, the procedure is still accepted. In the gastroenterology department at the Bnai Zion Medical Center, a serious interaction is ongoing with patients' legal guardians, where detailed information is given about the inefficiency of the tube procedure...
October 13, 2017: Age and Ageing
https://www.readbyqxmd.com/read/29036302/a-prospective-observational-study-to-investigate-utility-of-the-delirium-observational-screening-scale-doss-to-detect-delirium-in-care-home-residents
#12
E A Teale, T Munyombwe, M Schuurmans, N Siddiqi, J Young
Background: care home residents are particularly at risk of delirium due to high prevalence of dementia. The Delirium Observation Screening Scale (DOSS) identifies behavioural changes associated delirium onset that nursing staff are uniquely placed to recognise. We tested the psychometric properties of the DOSS in UK care homes compared with the Confusion Assessment Method (CAM). Design: prospective observational cohort study performed between 1 March 2015 and 30 June 2016...
October 5, 2017: Age and Ageing
https://www.readbyqxmd.com/read/29036394/management-of-acute-coronary-syndromes-in-older-people
#13
Roy L Soiza
No abstract text is available yet for this article.
September 28, 2017: Age and Ageing
https://www.readbyqxmd.com/read/29036509/medication-usage-change-in-older-people-65-in-england-over-20-years-findings-from-cfas-i-and-cfas-ii
#14
L Gao, Ian Maidment, Fiona E Matthews, Louise Robinson, Carol Brayne
Background: medical practice has changed over the last decades reflecting the ageing population, when multi-morbidity requiring multiple medications is more common. Objective: describe and quantify self-reported medicine use including both prescription and over the counter medicines in two comparable population-based studies of older people (65+) in England and to assess the nature and scale of polypharmacy. Methods: data used were from two separate population-based studies; the Cognitive Function Ageing Study I and II...
September 26, 2017: Age and Ageing
https://www.readbyqxmd.com/read/29036276/multimorbidity-will-it-stand-the-test-of-time
#15
Joanna C Ford, John A Ford
The concept of multimorbidity has risen in popularity over the past few years. It is use has led to, or coincided with, an increased recognition that patients often have more than one health problem which should not be treated in isolation. The motivation for more holistic, person-centred care that lies behind multimorbidity is to be welcomed. The 2016 National Institute for Health and Care Excellence multimorbidity management guideline helpfully makes recommendations in key areas that are important in the care of patients with complicated medical problems...
September 26, 2017: Age and Ageing
https://www.readbyqxmd.com/read/29036424/frailty-and-healthcare-costs-longitudinal-results-of-a-prospective-cohort-study
#16
André Hajek, Jens-Oliver Bock, Kai-Uwe Saum, Herbert Matschinger, Hermann Brenner, Bernd Holleczek, Walter E Haefeli, Dirk Heider, Hans-Helmut König
Objective: to investigate how frailty and frailty symptoms affect healthcare costs in older age longitudinally. Methods: data were gathered from a prospective cohort study in Saarland, Germany (two waves with 3-year interval, n = 1,636 aged 57-84 years at baseline). Frailty was assessed by the five Fried frailty criteria. Frailty was defined as having at least three criteria, the presence of 1-2 criteria as 'pre-frail'. Healthcare costs were quantified based on self-reported healthcare use in the sectors of inpatient treatment, outpatient treatment, professional nursing care and informal care as well as the provision of pharmaceuticals, medical supplies and dental prostheses...
September 21, 2017: Age and Ageing
https://www.readbyqxmd.com/read/28927235/the-effect-of-complex-interventions-on-supporting-self-care-among-community-dwelling-older-adults-a-systematic-review-and-meta-analysis
#17
Kwan Ching Wong, Frances Kam Yuet Wong, W F Yeung, Katherine Chang
Background: self-care is critical to enable community-dwelling older adults to live independently. Complex interventions have emerged as a strategy to support self-care, but their effectiveness is unknown. Our objective was to review systematically their effectiveness on both positive (increased scores in self-rated health, Activities of Daily Living, Instrumental Activities of Daily Living, quality of life) and negative aspects (increased incidence of falls, fear of falling, hospital and nursing home admission, increased depression score), and to determine which intervention components explain the observed effects...
September 13, 2017: Age and Ageing
https://www.readbyqxmd.com/read/28985259/effectiveness-and-safety-of-oral-anticoagulants-in-older-patients-with-atrial-fibrillation-a-systematic-review-and-meta-regression-analysis
#18
Ying Bai, Shi-Dong Guo, Hai Deng, Alena Shantsila, Laurent Fauchier, Chang-Sheng Ma, Gregory Y H Lip
Background and objective: the study analysed the effectiveness and safety of warfarin use compared with warfarin non-use and non-vitamin K antagonist oral anticoagulants (NOACs) in atrial fibrillation (AF) patients aged ≥65 years. Methods: after searching PubMed and the Cochrane Library, 26 studies were included, with 10 comparing warfarin with warfarin non-use and 16 comparing warfarin with NOACs, in older AF patients (≥65 years). Results: warfarin use was superior to no antithrombotic therapy [relative risk (RR) 0...
September 8, 2017: Age and Ageing
https://www.readbyqxmd.com/read/28985251/reply-to-seasonal-ambient-changes-influence-inpatient-falls-magota-et-al
#19
P J López-Soto, M H Smolensky, L L Sackett-Lundeen, L M A Rodríguez-Borrego
No abstract text is available yet for this article.
September 8, 2017: Age and Ageing
https://www.readbyqxmd.com/read/28985261/lessons-learned-from-a-case-of-candida-discitis
#20
Karen Waldon, Tapan Chattopadhyay
No abstract text is available yet for this article.
September 1, 2017: Age and Ageing
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