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Journal of the Neurological Sciences

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https://www.readbyqxmd.com/read/30419366/decreased-fractal-dimension-of-heart-rate-variability-is-associated-with-early-neurological-deterioration-and-recurrent-ischemic-stroke-after-acute-ischemic-stroke
#1
Lanying He, Jian Wang, Lili Zhang, Xiaoqiang Zhang, Weiwei Dong, Hao Yang
Acute ischemic stroke (AIS) may experience early neurological deterioration (END) and have high risks of recurrent ischemic strokes (RIS), which are often associated with a poor outcome. Post-stroke prognosis is associated with autonomic status. Recently, studies showed that heart rate variability (HRV) is an early outcome predictor in acute stroke patients. The purpose of our study was to investigate association decreased HRV by fractal dimension (FD) with early END within 72 h of admission and 1-year RIS...
November 5, 2018: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/30419370/ebv-nmda-double-positive-encephalitis-in-an-immunocompromised-patient
#2
LETTER
Garré Jinte, Sprengers Mathieu, Van Melkebeke Deborah, Laureys Guy
No abstract text is available yet for this article.
November 3, 2018: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/30419369/influence-of-the-circle-of-willis-on-leptomeningeal-collateral-flow-in-anterior-circulation-occlusive-stroke-friend-or-foe
#3
Katharina Millesi, Johannes Sebastian Mutzenbach, Monika Killer-Oberpfalzer, Constantin Hecker, Lukas Machegger, Nele Bubel, Christian Ramesmayer, Slaven Pikija
BACKGROUND: Clinical outcome after large vessel occlusion (LVO) stroke depends on collateral integrity. We aimed to evaluate whether the completeness of the circle of Willis (CoW) and anterior temporal artery (ATA) determines the status of leptomeningeal collaterals (LC) in patients with acute LVO (internal carotid artery (ICA) and middle cerebral artery M1 (MCA) occlusion) treated with endovascular thrombectomy. PATIENTS AND METHODS: LC, cross-flow through the anterior communicating artery (ACoA), presence of the ipsilateral posterior communicating artery (IpsiPCoA) and presence of the ATA were evaluated using CT angiography...
November 3, 2018: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/30419367/adult-csf-total-protein-higher-upper-reference-limits-should-be-considered-worldwide-a-web-based-survey
#4
Pierre R Bourque, Ari Breiner, David Moher, John Brooks, Harald Hegen, Florian Deisenhammer, Christopher R McCudden
BACKGROUND: The cerebrospinal fluid total protein level (CSF-TP) is commonly used as a potential marker of infectious or immune disease of the CNS and PNS. Recent laboratory reference studies indicate that the antiquated single upper reference limit of 0.45 g/L commonly used by hospital laboratories and widely quoted in medical literature is a significant underestimation. METHODS: We distributed worldwide a web-based survey comprised of three questions: 1. What is the CSF-TP upper limit used at your institution? 2...
November 3, 2018: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/30401491/concurrent-guillain-barr%C3%A3-syndrome-transverse-myelitis-and-encephalitis-post-zika-and-multiple-arboviral-immunity
#5
LETTER
Sora Yasri, Viroj Wiwanitkit
No abstract text is available yet for this article.
November 2, 2018: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/30401490/editorial-for-adult-csf-total-protein-higher-upper-reference-limits-should-be-considered-worldwide-a-web-based-survey
#6
EDITORIAL
Wolfgang Grisold
No abstract text is available yet for this article.
November 2, 2018: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/30412900/opsoclonus-myoclonus-encephalopathy-induced-by-cefepime
#7
LETTER
Karlo J Lizarraga, Deborah O Heros, David Adams, Anthony E Lang, Andres M Kanner
No abstract text is available yet for this article.
November 1, 2018: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/30399462/ocular-myasthenia-gravis-patients-following-the-administration-of-tacrolimus-and-steroids
#8
LETTER
Taku Omata, Kaori Fukui, Kazuo Kodama, Yoshimi Watanabe, Hiromi Aoyama, Katsunori Fujii, Naoki Shimojo
No abstract text is available yet for this article.
October 30, 2018: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/30412901/plasma-levels-of-soluble-ncam-in-multiple-sclerosis
#9
Nicole Ziliotto, Robert Zivadinov, Dejan Jakimovski, Marcello Baroni, Veronica Tisato, Paola Secchiero, Niels Bergsland, Deepa P Ramasamy, Bianca Weinstock-Guttman, Francesco Bernardi, Murali Ramanathan, Giovanna Marchetti
In multiple sclerosis (MS), several adhesion molecules are involved within the central nervous system in inflammatory and neurodegenerative processes that are associated to progressive disability and increasing brain atrophy. The neural cell adhesion molecule (NCAM) has been suggested to participate in the reparative mechanisms and in the remyelination processes, key issues in MS pathology. We aimed at investigating plasma levels of the seldom investigated soluble (s)NCAM, and as comparison those of intercellular adhesion molecule-1 (sICAM-1) and vascular adhesion molecule-1 (sVCAM-1), and their association with clinical and MRI measures of lesion volumes and of global and regional atrophy...
October 28, 2018: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/30396032/leukocyte-telomere-shortening-in-huntington-s-disease
#10
Daniela Scarabino, Liana Veneziano, Martina Peconi, Marina Frontali, Elide Mantuano, Rosa Maria Corbo
Huntington's disease (HD) is an autosomal dominant neurodegenerative disease caused by an expanded CAG repeat. Though symptom onset commonly occurs at midlife and inversely correlates with the CAG repeat expansion, age at clinical onset and progression rate are variable. In the present study we investigated the relationship between leukocyte telomere length (LTL) and HD development. LTL was measured by real-time PCR in manifest HD patients (HD, n = 62), pre-manifest HD patients (pre-HD, n = 38), and age-matched controls (n = 76)...
October 28, 2018: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/30391820/development-of-permanent-brain-damage-after-subacute-encephalopathy-with-seizures-in-alcoholics
#11
Coline Duwicquet, Julien Biberon, Philippe Corcia, Bertrand De Toffol, Nadège Limousin
PURPOSE: To describe additional cases of subacute encephalopathy with seizures in alcoholics (SESA) syndrome, and to question the clinical and radiological course. METHODS: We retrospectively analyzed the clinical characteristics, electroencephalography (EEG), MRI studies at the admission and over the following 6 months of 5 cases of SESA syndrome visited our neurology department between 2010 and 2016. RESULTS: Five middle-aged males with history of chronic alcohol abuse were admitted for confusion, neurological deficit and seizures...
October 25, 2018: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/30391822/mibg-myocardial-scintigraphy-in-progressive-supranuclear-palsy
#12
Takashi Kamada, Shiroh Miura, Hiroshi Kida, Ken-Ichi Irie, Yoshihiro Yamanishi, Tomoaki Hoshino, Takayuki Taniwaki
BACKGROUND AND OBJECTIVES: Meta-iodobenzylguanidine (MIBG) myocardial scintigraphy is an effective tool for distinguishing Parkinson's disease (PD) from other diseases accompanied by parkinsonism. Unlike other Parkinsonian diseases, in PD, MIBG accumulation in the heart tends to decrease. However, previous studies have reported that a decrease in MIBG accumulation also occurs in progressive supranuclear palsy (PSP). Thus, we analyzed the relationship between the degree of MIBG accumulation decrease, clinical symptoms, and brainstem atrophy in PSP...
October 22, 2018: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/30391819/identification-of-35-cag-repeats-within-atxn1-as-the-probable-shortest-pathogenic-allele-for-spinalcerebellar-ataxia-type-1
#13
LETTER
Yu Zhang, Minjin Wang, Ling Liu
No abstract text is available yet for this article.
October 22, 2018: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/30391823/predictive-score-for-oral-corticosteroid-induced-initial-worsening-of-seropositive-generalized-myasthenia-gravis
#14
Tetsuya Kanai, Akiyuki Uzawa, Naoki Kawaguchi, Fumiko Oda, Yukiko Ozawa, Keiichi Himuro, Satoshi Kuwabara
BACKGROUND: Initial worsening of symptoms after the start of corticosteroid administration is a major concern in the treatment of myasthenia gravis (MG). However, the risk factors or specific patient backgrounds related to this issue have not been fully understood. We aimed to determine the risk factors and developed a scoring system for predicting initial worsening in generalized MG. METHODS: We enrolled 62 generalized MG patients with anti-acetylcholine receptor antibody...
October 19, 2018: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/30366248/three-novel-recessive-dysf-mutations-identified-in-three-patients-with-muscular-dystrophy-limb-girdle-type-2b
#15
LETTER
Mariko Okubo, Aritoshi Iida, Shinichiro Hayashi, Madoka Mori-Yoshimura, Yasushi Oya, Akihiro Watanabe, Hajime Arahata, Rasha El Sherif, Satoru Noguchi, Ichizo Nishino
No abstract text is available yet for this article.
October 16, 2018: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/30391821/outcome-of-human-peripheral-nerve-repair-interventions-using-conduits-a-systematic-review
#16
REVIEW
Sunil K Narayan, Murugesan Arumugam, Ravikumar Chittoria
BACKGROUND & OBJECTIVE: Peripheral nerve injury is very common, but repair is a challenging medical problem. Advances in medical sciences and technologies have however made tremendous breakthroughs in understanding repair mechanisms in nerve injury making this a fascinating area in neurotherapeutics. However, a systematic analysis of existing data is lacking, the present study was attempted to review existing literature in nerve repair studies in human beings and analyse outcome systematically...
October 10, 2018: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/30321796/hypothalamic-and-pituitary-dysfunction-is-common-in-tubercular-meningitis-a-prospective-study-from-a-tertiary-care-center-in-northern-india
#17
Hafeez Mohammed, Manoj Kumar Goyal, Pinaki Dutta, Kusum Sharma, Manish Modi, Faisal Shah, Ritu Shree, Anumiti Jain, Gourav Jain, Niranjan Khandelwal, Navneet Sharma, Vivek Lal
INTRODUCTION: Current literature is poor with respect to well conducted prospective studies of hypothalamic pituitary axis (HPA) dysfunction in tubercular meningitis (TBM). As hormonal deficiencies are associated with poor clinical outcome in various neurological and non-neurological disorders, we prospectively evaluated the hypothalamic pituitary axis (HPA) dysfunction in TBM. PATIENTS AND METHODS: Present study included newly diagnosed drug naive TBM patients (n = 63) at a tertiary care centre in Northern India...
October 9, 2018: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/30312901/effects-of-continuous-subcutaneous-apomorphine-infusion-in-parkinson-s-disease-without-cognitive-impairment-on-motor-cognitive-psychiatric-symptoms-and-quality-of-life
#18
Jean-François Houvenaghel, Sophie Drapier, Joan Duprez, Gabriel Hadrien Robert, Audrey Riou, Dominique Drapier, Paul Sauleau, Marc Vérin
INTRODUCTION: Treatment optimization using continuous subcutaneous apomorphine infusion (CSAI) improves the control of motor fluctuations of patients with Parkinson's disease (PD). Although CSAI seems to be cognitively and behaviorally safe and to improve the quality of life, very few studies have investigated its influence in these domains, especially in patients without cognitive impairment. METHODS: We estimated the impact of CSAI on motor symptoms, cognition, psychiatric domains and quality of life in parkinsonian patients without cognitive impairment by comparing the scores of 22 patients assessed before and 6 months after the start of add-on CSAI...
October 7, 2018: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/30316069/brain-mri-findings-in-children-and-adolescents-with-fabry-disease
#19
C Marchesoni, E Cisneros, P Pfister, P Yáñez, C Rollan, C Romero, I Kisinovsky, L Rattagan, L León Cejas, A Pardal, G Sevlever, R Reisin
OBJECTIVE: To evaluate the presence of white matter and hemorrhagic lesions in brain MRI of children and adolescents with Fabry disease (FD). METHODS: Brain MRI studies in 44 consecutive children and teenagers (20 boys, mean age 14.6 years, range 7-21 years) were evaluated using classic sequences as well as, GRE-weighted images, for white matter lesions (WML) and chronic microbleed detection. All patients lacked history of stroke or TIA. Brain MRI findings in 46 consecutive children and adolescents without FD, referred for the evaluation of headaches (36 females, mean age 14...
October 5, 2018: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/30312902/an-attempt-to-treat-ocular-flutter-and-opsoclonus-by-cerebellar-magnetic-stimulation
#20
LETTER
Yosuke Kudo, Eriko Sugawara, Koji Takahashi, Fumiaki Tanaka, Ken Johkura
No abstract text is available yet for this article.
October 4, 2018: Journal of the Neurological Sciences
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