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Journal of the Neurological Sciences

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https://www.readbyqxmd.com/read/30025235/toe-dystonia-in-parkinson-s-disease-impact-of-subthalamic-nucleus-deep-brain-stimulation
#1
Chloe Laurencin, Solveig Montaut, Christophe Vial, Lorraine Bernard, Sylvie Bin, Lucie Rascle, Gustavo Polo, Patrick Mertens, Teodor Danaila, Stephane Thobois
BACKGROUND: Off state toe dystonia (TD) is a symptom frequently encountered in Parkinson's disease (PD), but little is known about its evolution after subthalamic nucleus deep brain stimulation (STN-DBS). OBJECTIVE: To analyze the prevalence and the evolution of TD in PD patients candidate to STN-DBS. METHODS: Individual data of consecutive 130 PD patients who underwent STN-DBS between 2010 and 2015 were collected. RESULTS: Data were successfully collected in 95 patients...
July 12, 2018: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/30025236/resting-state-fmri-reveals-the-altered-synchronization-of-bold-signals-in-essential-tremor
#2
Pu Wang, Xiangdong Luo, Chengqing Zhong, Lili Yang, Fuqiang Guo, Nengwei Yu
Essential tremor (ET) is one of the most common movement disorders in humans. Nevertheless, there remain several controversies surrounding ET, such as whether it is a disorder of abnormal neuronal oscillations within the tremor network. In this work, the resting-state fMRI data were collected from 17 ET patients and 17 age- and gender-matched healthy controls. First, using FOur-dimensional (spatiotemporal) Consistency of local neural Activities (FOCA) the abnormal synchronization of fMRI signals in ET patients were investigated...
July 10, 2018: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/29961556/association-between-attention-deficit-hyperactivity-disorder-adhd-and-amyotrophic-lateral-sclerosis-als
#3
LETTER
Martina de Zwaan, Leonie Ebel, Susanne Petri, Joachim K Krauss, Reinhard Dengler
No abstract text is available yet for this article.
June 22, 2018: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/29958655/association-between-attention-deficit-hyperactivity-disorder-and-amyotrophic-lateral-sclerosis
#4
LETTER
Tomoyuki Kawada
No abstract text is available yet for this article.
June 21, 2018: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/29935918/response-to-screening-ability-of-cognitive-function-by-two-measures-in-patients-with-multiple-sclerosis
#5
LETTER
Elizabeth S Gromisch, Jeffrey G Portnoy, Frederick W Foley
No abstract text is available yet for this article.
June 14, 2018: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/29925464/screening-ability-of-cognitive-function-by-two-measures-in-patients-with-multiple-sclerosis
#6
LETTER
Tomoyuki Kawada
No abstract text is available yet for this article.
June 13, 2018: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/29910129/the-move-when-neurosciences-teach-us-to-better-teach-neurosciences
#7
EDITORIAL
Marc Vérin, Pascal Benquet
No abstract text is available yet for this article.
June 9, 2018: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/29910128/miming-neurological-syndromes-improves-medical-student-s-long-term-retention-and-delayed-recall-of-neurology
#8
Emmanuel Roze, Yulia Worbe, Céline Louapre, Aurélie Méneret, Cécile Delorme, Eavan McGovern, Marta Ruiz, Jean Capron, Raphaël Le Bouc, Stéphane Epelbaum, Sonia Alamowitch, Alexandre Duguet, Marie-Christine Renaud, Olivier Palombi, Tamara M Pringsheim, Constance Flamand-Roze, Olivier Steichen
Basic examination and diagnostic skills in neurology are important for every graduating medical student. However, a majority of medical students consider neurology as complex and difficult to master. We evaluate the impact a learner-friendly, innovative simulation-based training programme has on long-term retention and delayed recall of neurological semiology amongst third-year medical students from the University Pierre et Marie Curie in Paris, France. The 2013 class received standard teaching in neurological semiology...
June 7, 2018: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/29853250/formaldehyde-dna-damage-als-and-related-neurodegenerative-diseases
#9
EDITORIAL
Peter S Spencer
No abstract text is available yet for this article.
May 25, 2018: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/29807753/from-snow-to-hill-to-als-an-epidemiological-odyssey-in-search-of-als-causation
#10
REVIEW
Carmel Armon
BACKGROUND: Establishing mechanisms of disease causation in neurodegenerative diseases has long seemed to be beyond the pale of traditional epidemiological tools. Establishing a plausible mechanism for initiation of amyotrophic lateral sclerosis (ALS) has appeared a particularly elusive goal. This review shows that a likely mechanism for ALS initiation may be inferred by applying classical methods of epidemiological inference. KEY POINTS: Advances in characterizing the biology of ALS suggest that most cases of ALS are cortically-generated, part of the ALS-FTD spectrum, with focal onset and spread by contiguity within the motor super-network...
May 21, 2018: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/29801917/cocaine-as-a-potential-trigger-for-neuromyelitis-optica
#11
LETTER
Ahmed Z Obeidat
No abstract text is available yet for this article.
July 15, 2018: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/29801916/leukodystrophy-with-disorders-of-sex-development-due-to-wt1-mutations
#12
Paulo Victor Sgobbi Souza, Bruno Mattos Lombardi Badia, Luiz Henrique Libardi Silva, Carlos Alberto Castro Teixeira, Daniel Delgado Seneor, Vitor Dias Gomes Barrios Marin, Igor Braga Farias, Renan Braido Dias, Acary Souza Bulle Oliveira, Wladimir Bocca Vieira Rezende Pinto
BACKGROUND: Hypomyelinating leukodystrophies represent an expanding group of neurogenetic disorders characterized primarily by central nervous system hypomyelination and variable neurological and non-neurological involvement. Hypomyelinating disorders have been rarely associated with gonadal dysfunction, being mainly represented by hypogonadotrophic hypogonadism in 4H syndrome. WT1 gene-associated disorders are classically associated with complex phenotypes including early carcinogenic risk for gonadoblastoma and Wilms' tumor, chronic renal failure, nephrotic syndrome and sex developmental disorders in intersex disorders and ambiguous genitalia...
July 15, 2018: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/29801915/the-impact-of-very-short-transition-times-on-switching-from-natalizumab-to-fingolimod-on-imaging-and-clinical-effectiveness-outcomes-in-multiple-sclerosis
#13
Brandi Vollmer, Justin M Honce, Stefan Sillau, John R Corboy, Timothy Vollmer, Kavita Nair, Enrique Alvarez
BACKGROUND: Due to the recurrence of disease activity in multiple sclerosis (MS) patients, a washout period of <3 months has been suggested for the transition from natalizumab (NTZ) to fingolimod (FTY). However, very short transition periods of <1 month may be more beneficial. METHODS: Retrospective analysis of patients from the Rocky Mountain MS Center at the University of Colorado who were: a) on NTZ for ≥6 months prior to switching to FTY; b) had a transition period ≤ 6 months; and c) initiated FTY treatment prior to November 2013...
July 15, 2018: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/29801914/improvement-of-mouse-controlling-in-essential-tremor-by-a-tremor-filter-a-case-report
#14
LETTER
Roberto López-Blanco, Antonio Méndez-Guerrero, Miguel A Velasco
The interaction with electronic devices is crucial in our technological society. Hand kinetic tremor complicates mouse driving in Essential tremor patients. To solve this issue some technological solutions are available and accessible online. We present a 71-year-old patient with prominent mouse controlling tremor who improved with one of these systems.
July 15, 2018: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/29801913/progressive-spasticity-supranuclear-gaze-palsy-and-postural-instability-without-parkinsonism-what-s-in-a-phenotype
#15
L Ricciardi, M J Edwards, A Fasano, K P Bhatia, M Stamelou
We present a series of patients with vertical supranuclear gaze palsy, postural instability with falls, and progressive spasticity, who mimic Progressive Supranuclear Palsy - Richardson's syndrome (PSP-R) but have no parkinsonism, and in whom dopamine transporter imaging is normal. We suggest possible aetiologies for this constellation of symptoms, discuss the possible origin of these signs and highlight this phenotype as it may mimic atypical parkinsonism and in particular PSP.
July 15, 2018: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/29801912/long-term-outcomes-of-acute-ischemic-stroke-patients-treated-with-endovascular-thrombectomy-a-real-world-experience
#16
Wenbo Zhao, Shuyi Shang, Chuanhui Li, Longfei Wu, Chuanjie Wu, Jian Chen, Haiqing Song, Hongqi Zhang, Yunzhou Zhang, Jiangang Duan, Wuwei Feng, Xunming Ji
BACKGROUND AND PURPOSE: Long-term follow-up of large trials have confirmed the superiority of endovascular thrombectomy (ET) for treating acute ischemic stroke (AIS). However, it is still unknown whether these results can be generalized to clinical practice. In this study, we aimed to determine the long-term outcomes of AIS post-ET in the real-world clinical practice. METHODS: This observational study is based on a single-center prospective registry study. AIS patients were treated with second-generation stent retrievers from December 2012 to April 2016...
July 15, 2018: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/29801911/the-many-faces-of-neurocysticercosis
#17
Pooja Raibagkar, Aaron L Berkowitz
Neurocysticercosis (NCC) is the most common parasitic disease of the central nervous system, and one of the most common causes of epilepsy worldwide. The radiologic appearance of neurocysticercosis varies depending on the stage of the disease, and the stage of the disease determines the appropriate treatment. In this article, we review key neuroimaging characteristics of the stages of NCC (vesicular, colloidal, granular, and calcified) and treatment principles for these different stages of the disease.
July 15, 2018: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/29801910/perampanel-as-adjunctive-therapy-in-highly-refractory-epilepsies-real-world-data-from-an-italian-tertiary-care-epilepsy-centre
#18
Alessandra Morano, Jinane Fattouch, Mariarita Albini, Sara Casciato, Martina Fanella, Luca Manfredi Basili, Alessandro Viganò, Mario Manfredi, Anna Teresa Giallonardo, Carlo Di Bonaventura
Perampanel (PER) is a selective non-competitive α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptor antagonist, licensed as adjunctive therapy in focal epilepsy and primary generalized tonic-clonic seizures (pGTCSs). We performed a retrospective study on highly refractory adult patients taking PER, with 1-year follow-up. Retention rate represented the primary outcome of our work; seizure frequency reduction (≥50%), "switch rate" and proportion of adverse events (AEs) were evaluated as secondary endpoints...
July 15, 2018: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/29801909/infantile-traumatic-brain-injury-with-a-biphasic-clinical-course-and-late-reduced-diffusion
#19
Nanako Takase, Noboru Igarashi, Hiromichi Taneichi, Kumi Yasukawa, Takafumi Honda, Hiromichi Hamada, Jun-Ichi Takanashi
Reduced diffusion in the subcortical white matter has been reported in some infants with traumatic brain injury (TBI), including abusive head trauma. However, the pathomechanisms of the lesions and clinical features are uncertain. We herein report two infants with TBI who presented with biphasic clinical courses and late reduced diffusion in the subcortical white matter, and reviewed seven clinically and radiologically similar patients with TBI. Their clinical features (secondary neurological symptoms on days 3 to 6) and radiological findings (normal diffusion on days 1 to 2, followed by reduced diffusion on days 3 to 6) are very similar to those observed in patients with acute encephalopathy with biphasic seizures and late reduced diffusion (AESD)...
July 15, 2018: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/29801908/the-clinical-utility-of-a-30-minute-neuropsychological-assessment-battery-in-inpatient-stroke-rehabilitation
#20
Abhishek Jaywant, Joan Toglia, Faith M Gunning, Michael W O'Dell
Cognitive assessment is an important component of inpatient stroke rehabilitation. Few studies have empirically evaluated the clinical utility of specific neuropsychological measures in this setting. We investigated the psychometric properties and clinical utility of a 30-minute neuropsychological battery developed by the National Institute of Neurologic Disorders and Stroke (NINDS) and the Canadian Stroke Network (CSN). Clinical data were analyzed from 100 individuals with mild-moderate stroke severity on an acute inpatient rehabilitation unit who completed the NINDS-CSN battery at admission...
July 15, 2018: Journal of the Neurological Sciences
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