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Journal of the Neurological Sciences

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https://www.readbyqxmd.com/read/28526215/cardiac-takotsubo-syndrome-in-association-with-cerebral-renal-gastrointestinal-vascular-and-perhaps-total-body-takotsubo-syndrome
#1
LETTER
John E Madias
No abstract text is available yet for this article.
May 12, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28511898/is-the-takotsubo-syndrome-a-brain-heart-or-multiorgan-disorder
#2
LETTER
Josef Finsterer, Claudia Stollberger
No abstract text is available yet for this article.
May 12, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28511897/takotsubo-in-amyotrophic-lateral-sclerosis
#3
LETTER
Josef Finsterer, Claudia Stöllberger
No abstract text is available yet for this article.
May 10, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28477718/the-relationship-between-interventionists-experience-and-clinical-and-radiological-outcome-in-intra-arterial-treatment-for-acute-ischemic-stroke-a-mr-clean-pretrial-survey
#4
Debbie Beumer, Tiemen H van Boxtel, Stefanie Schipperen, Wim H van Zwam, Geert J Lycklama À Nijeholt, Patrick A Brouwer, Sjoerd F M Jenniskens, Wouter J Schonewille, Jan Albert Vos, Aad van der Lugt, Yvo B Roos, Charles B Majoie, Robert J van Oostenbrugge, Diederik W J Dippel
BACKGROUND: Intra-arterial treatment in acute ischemic stroke is safe and effective as recently shown in several randomized clinical trials. The level of experience of the interventionist performing the IAT procedure has not been studied. The present study investigates effects of interventionists' experience on technical aspects of the procedure and clinical outcome of the patient. METHODS: In this study of 313 patients with a proximal intracranial arterial anterior circulation occlusion, treated in the Netherlands from 2002 until participation in the Multicenter Randomized Clinical trial of Endovascular treatment for acute ischemic stroke (MR CLEAN), data were collected retrospectively...
June 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28477717/a-multidisciplinary-medical-network-approach-is-crucial-for-increasing-the-number-of-autopsies-for-prion-disease-reply-to-how-can-we-increase-the-numbers-of-autopsies-for-prion-disease-a-model-system-in-japan
#5
LETTER
https://www.readbyqxmd.com/read/28477716/the-research-on-association-of-copy-number-variation-in-chromosome-9p21-region-with-atherothrombotic-stroke-in-the-han-chinese-population
#6
Hua Liu, Min Yang, Xiaoming Wang, Yifei Ji, Jin Zhao, Wei Liu, Jian Zheng
BACKGROUND/PURPOSE: The copy number variants (CNVs) contain more genetic information compared with SNPs. The aim of this study was to elucidate whether the CNVs in Chromosome 9p21 region are associated with increased risk of Atherothrombotic stroke (ATS) in a Han Chinese population. METHODS: A case-controlled association study was conducted in which only patients with ATS were enrolled. The CNVs were detected by the method of multiplex competitive amplification...
June 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28477715/how-variable-are-psychogenic-nonepileptic-seizures-a-retrospective-semiological-study
#7
Ali A Asadi-Pooya, Jennifer Tinker, Elizabeth W Fletman
PURPOSE: To classify patients with psychogenic nonepileptic seizures (PNES) according to a recently proposed classification system and investigate the variability of PNES semiology. METHODS: We retrospectively investigated all patients with PNES admitted at the Jefferson Comprehensive Epilepsy Center from 2012 through 2016. We classified their seizures after retrospectively reviewing their recorded videos during their video-EEG monitoring admission and investigated the seizure variability...
June 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28477714/-18-f-fallypride-pet-ct-of-dopamine-d2-d3-receptors-in-patients-with-sporadic-amyotrophic-lateral-sclerosis
#8
Xiaoling Fu, Wenjia Zhu, Zhe Guo, Gangming Shu, Fang Cui, Fei Yang, Ying Zhang, Yuting Ren, Xiaojun Zhang, Xiaolan Zhang, Zhaohui Chen, Li Ling, Xusheng Huang, Jinming Zhang
Amyotrophic lateral sclerosis (ALS) is a progressive and fatal neurodegenerative disease with unclear pathogenesis. To date, there have been no reports regarding the distribution of dopamine receptors outside the striatum in ALS patients. In this study, 17 ALS patients and 11 healthy controls underwent (18)F-fallypride positron emission tomography/computed tomography (PET/CT) and completed cognitive-related tests for assessment of the distribution of dopamine receptors inside and outside the striatum in ALS and evaluation of the relationships between the distribution of dopamine receptors and cognitive function...
June 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28477713/factors-influencing-interest-in-the-brain-related-sciences-in-a-uk-cohort
#9
LETTER
Charlotte Burford, Emma Alexander, William Sloper, Marian Huett
No abstract text is available yet for this article.
June 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28477712/effectiveness-and-safety-of-immunosuppressive-therapy-in-neuromyelitis-optica-spectrum-disorder-during-pregnancy
#10
Bingxin Shi, Mangsuo Zhao, Tongchao Geng, Liyan Qiao, Yapeng Zhao, Xiuli Zhao
OBJECTIVE: To evaluate the effectiveness and safety of immunosuppressive therapy in neuromyelitis optica spectrum disorder (NMOSD) during pregnancy. METHODS: Sixteen NMOSD patients who had at least one pregnancy after NMOSD onset were enrolled. The patients were divided into two groups according to whether they received immunosuppressive therapy during pregnancy. The annual relapse rate (ARR) before pregnancy (BP); during the first (DP1), second (DP2), and third trimesters (DP3); first trimester postpartum (PP1); and second trimester postpartum (PP2) were calculated...
June 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28477711/association-analysis-of-polymorphisms-in-vmat2-and-tmem106b-genes-for-parkinson-s-disease-amyotrophic-lateral-sclerosis-and-multiple-system-atrophy
#11
Tao Hu, Yongping Chen, Ruwei Ou, Qianqian Wei, Bei Cao, Bi Zhao, Ying Wu, Wei Song, Xueping Chen, Hui-Fang Shang
BACKGROUND: The vesicular monoamine transporter type 2 (VMAT2) and transmembrane Protein 106B (TMEM106B) were reported to be associated with neurodegenerative diseases. Recent studies found that two polymorphisms (rs363371 and rs363324) in VMAT2 might be a risk factor for Parkinson's disease (PD) in Caucasians, while the two other variants (rs1990622 and rs3173615) in TMEM106B increased the risk for frontotemporal dementia (FTD). Considering the overlap between clinical manifestation and pathologic characteristics in neurodegenerative diseases, we conducted a large-sample study to investigate the associations between these four polymorphisms and the risk for PD, sporadic amyotrophic lateral sclerosis (SALS), and multiple system atrophy (MSA) in a Chinese patient population...
June 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28477710/three-novel-missense-mutations-in-slc20a2-associated-with-idiopathic-basal-ganglia-calcification
#12
LETTER
Elisa Rubino, Elisa Giorgio, Massimiliano Godani, Enrico Grosso, Maurizio Zibetti, Leonardo Lopiano, Patrizia Ferrero, Sergio Duca, Leonardo Moretti, Salvatore Gallone, Innocenzo Rainero, Alfredo Brusco
No abstract text is available yet for this article.
June 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28477709/liquid-levodopa-carbidopa-in-advanced-parkinson-s-disease-with-motor-complications
#13
Hui-Jun Yang, Gwanhee Ehm, Young Eun Kim, Ji Young Yun, Woong-Woo Lee, Aryun Kim, Han-Joon Kim, Beomseok Jeon
While levodopa, carbidopa, ascorbic acid solution (LCAS) therapy has been used in patients with advanced Parkinson's disease (PD) for many years, long-term follow-up data is scarce. The present study aimed to determine the long-term retention rate for LCAS therapy, and to identify the causes of LCAS therapy withdrawal. Our study included a series of 38 patients with PD (14 men and 24 women) who underwent LCAS treatment between 2011 and 2013 to alleviate motor complications that were not satisfactorily controlled by optimized conventional anti-parkinsonian treatment at the Seoul National University Hospital...
June 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28477708/impaired-cholinergic-transmission-in-patients-with-parkinson-s-disease-and-olfactory-dysfunction
#14
Viviana Versace, Patrick B Langthaler, Luca Sebastianelli, Yvonne Höller, Francesco Brigo, Andrea Orioli, Leopold Saltuari, Raffaele Nardone
Olfactory dysfunction represents a frequent and disturbing non-motor manifestation of Parkinson's disease (PD). The pathophysiology of olfactory dysfunction in PD is still poorly understood. Experimental evidence suggests that olfactory impairment could be related to central cholinergic dysfunction. Short latency afferent inhibition (SAI) technique gives the opportunity to test an inhibitory cholinergic circuit in the human cerebral motor cortex. The objective of the study was to assess the cholinergic function, as measured by SAI, in PD patients with different degrees of olfactory dysfunction...
June 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28477707/comparison-of-diagnostic-utility-of-semi-quantitative-analysis-for-dat-spect-for-distinguishing-dlb-from-ad
#15
Soichiro Shimizu, Nayuta Namioka, Daisuke Hirose, Hidekazu Kanetaka, Kentaro Hirao, Hirokuni Hatanaka, Naoto Takenoshita, Yoshitsugu Kaneko, Yusuke Ogawa, Akito Tsugawa, Takahiko Umahara, Hirofumi Sakurai, Haruo Hanyu
PURPOSE: It is widely known that there is low striatal (123)I-FP-CIT dopamine transporter single photon emission computed tomography (DAT-SPECT) uptake in patients with dementia with Lewy bodies (DLB). However, a consistent quantitative evaluation method for DAT-SPECT has not yet been established. There are two semi-quantitative software packages for DAT-SPECT available in Japan, namely, DaTView and DaTQUANT. The aim of this study was to identify which of these is superior for distinguishing DLB from AD...
June 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28477706/acute-intermittent-porphyria-presenting-as-posterior-reversible-encephalopathy-syndrome-with-hyperperfusion-in-bilateral-occipital-lobes-a-case-report
#16
LETTER
Yasuhiro Sakashita, Toshio Hamada, Tomohiko Machiya, Masahito Yamada
No abstract text is available yet for this article.
June 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28477705/a-quantitative-method-for-the-assessment-of-dysarthrophonia-in-myasthenia-gravis
#17
Kostas Konstantopoulos, Yiolanda-Panayiota Christou, Paris Vogazianos, Eleni Zamba-Papanicolaou, Kleopas A Kleopa
Speech and voice symptomatology (dysarthrophonia) are often reported by patients with myasthenia gravis (MG). However, they have been poorly investigated despite their significant impact on quality of life. Quantitative methods for the assessment of dysarthrοphonia could facilitate the evaluation of these common MG symptoms. The goal of this study was to investigate the phonatory (sustained phonation and reading) and speech (diadochokinesis) function in MG patients using quantitative measures. The voice/speech of 12 MG patients (7 with anti-AchR and 5 with anti-MuSK antibodies) and 24 age-matched healthy controls was recorded and analyzed using electroglottography (EGG) and speech acoustics...
June 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28477704/quantitative-assessment-of-autonomic-symptom-burden-in-postural-tachycardia-syndrome-pots
#18
Natalie A Rea, Corey L Campbell, Melissa M Cortez
Postural tachycardia syndrome (PoTS) is a poorly understood disorder characterized by excessive tachycardia in the upright position. In addition, patients with PoTS often complain of non-postural symptoms, including fatigue, gastrointestinal and vasomotor fluctuations. The present study quantitatively assessed autonomic symptom burden in PoTS patients (n=32) using the COMPASS-31, compared to that of autonomic failure/neuropathy (AF/N; n=47) and asymptomatic, healthy controls (n=32). Using AIC model selection and regression analysis, we found differences in the contribution of individual COMPASS-31 domains, depending on the autonomic disorder...
June 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28477703/indoleamine-2-3-dioxygenase-ido-2-polymorphisms-are-not-associated-with-multiple-sclerosis-in-italians
#19
Cristina Agliardi, Franca Rosa Guerini, Milena Zanzottera, Marco Rovaris, Domenico Caputo, Mario Clerici
Indoleamine 2,3 dioxygenase (IDO)1 and IDO2 are enzymes playing a pivotal role in the metabolism of tryptophan and in immune modulation. IDO2, in particular, was recently suggested to drive B cell-mediated autoimmune diseases. Two functional polymorphisms within the IDO2 gene are described that result in the production of enzymes with suppressed activity; we analyzed these polymorphisms in a cohort of Italian multiple sclerosis patients (MS). R248W (rs10109853) and Y359STOP (rs4503083) IDO2 polymorphisms were analyzed in 1355 Caucasian Italians (675 MS patients and 680 healthy controls) using Allelic discrimination Real-time approach with predesigned TaqMan probes...
June 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28477702/robotic-gait-training-in-multiple-sclerosis-rehabilitation-can-virtual-reality-make-the-difference-findings-from-a-randomized-controlled-trial
#20
Rocco Salvatore Calabrò, Margherita Russo, Antonino Naro, Rosaria De Luca, Antonino Leo, Provvidenza Tomasello, Francesco Molonia, Vincenzo Dattola, Alessia Bramanti, Placido Bramanti
Gait, coordination, and balance may be severely compromised in patients with multiple sclerosis (MS), with considerable consequences on the patient's daily living activities, psychological status and quality of life. For this reason, MS patients may benefit from robotic-rehabilitation and virtual reality training sessions. Aim of the present study was to assess the efficacy of robot-assisted gait training (RAGT) equipped with virtual reality (VR) system in MS patients with walking disabilities (EDSS 4.0 to 5...
June 15, 2017: Journal of the Neurological Sciences
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