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Journal of Child Psychology and Psychiatry, and Allied Disciplines

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https://www.readbyqxmd.com/read/28627743/polygenic-scores-for-schizophrenia-and-educational-attainment-are-associated-with-behavioural-problems-in-early-childhood-in-the-general-population
#1
Philip R Jansen, Tinca J C Polderman, Koen Bolhuis, Jan van der Ende, Vincent W V Jaddoe, Frank C Verhulst, Tonya White, Danielle Posthuma, Henning Tiemeier
BACKGROUND: Genome-wide association studies in adults have identified numerous genetic variants related to psychiatric disorders and related traits, such as schizophrenia and educational attainment. However, the effects of these genetic variants on behaviour in the general population remain to be fully understood, particularly in younger populations. We investigated whether polygenic scores of five psychiatric disorders and educational attainment are related to emotional and behaviour problems during early childhood...
June 19, 2017: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/28589541/female-specific-association-of-nos1-genotype-with-white-matter-microstructure-in-adhd-patients-and-controls
#2
Hanneke van Ewijk, Janita Bralten, Esther D A van Duin, Marina Hakobjan, Jan K Buitelaar, Dirk J Heslenfeld, Pieter J Hoekstra, Catharina Hartman, Martine Hoogman, Jaap Oosterlaan, Barbara Franke
BACKGROUND: The nitric oxide synthase gene (NOS1) exon 1f (ex1f) VNTR is a known genetic risk factor for Attention-Deficit/Hyperactivity Disorder (ADHD), particularly in females. NOS1 plays an important role in neurite outgrowth and may thus influence brain development, specifically white matter (WM) microstructure, which is known to be altered in ADHD. The current study aimed to investigate whether NOS1 is associated with WM microstructure in (female) individuals with and without ADHD...
June 7, 2017: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/28573761/sex-differences-in-the-associations-between-vagal-reactivity-and-oppositional-defiant-disorder-symptoms
#3
Pablo Vidal-Ribas, Andrew Pickles, Florin Tibu, Helen Sharp, Jonathan Hill
BACKGROUND: Vagal reactivity to stress in children has been associated with future psychiatric outcomes. However, results have been mixed possibly because these effects are in opposite direction in boys and girls. These sex differences are relevant in the context of development of psychopathology, whereby the rates of psychiatric disorders differ by sex. In this study, we aimed to examine the association between vagal reactivity, assessed as a reduction in respiratory sinus arrhythmia (RSA) in response to a challenge, and the development of future oppositional defiant disorder (ODD) symptoms in boys and girls...
June 2, 2017: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/28573672/memo-an-mhealth-intervention-to-prevent-the-onset-of-depression-in-adolescents-a-double-blind-randomised-placebo-controlled-trial
#4
Robyn Whittaker, Karolina Stasiak, Heather McDowell, Iain Doherty, Matthew Shepherd, Shireen Chua, Enid Dorey, Varsha Parag, Shanthi Ameratunga, Anthony Rodgers, Sally Merry
BACKGROUND: Depression often starts in adolescence making it an ideal time to intervene. We developed a universal cognitive behavioural therapy-based programme (MEMO CBT) to be delivered via multimedia mobile phone messages for teens. METHODS: We conducted a prospective multicentre, randomised, placebo-controlled superiority trial in 15 high schools in Auckland, New Zealand, comparing MEMO CBT with a control programme [MEMO control] matched for intensity and type of message but with alternative content not targeting depression...
June 2, 2017: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/28569044/anxiety-disorders-gender-nonconformity-bullying-and-self-esteem-in-sexual-minority-adolescents-prospective-birth-cohort-study
#5
Abbeygail Jones, Emily Robinson, Olakunle Oginni, Qazi Rahman, Katharine A Rimes
BACKGROUND: Sexual minority adolescents (i.e. youth not exclusively heterosexual) report more anxiety than heterosexual youth on symptom questionnaires but no research has used standardised diagnostic tools to investigate anxiety disorder risk. This study uses a UK birth cohort to investigate the risk of anxiety disorders in sexual minority and heterosexual youth using a computerised structured clinical interview and explores the influence of gender nonconformity, bullying and self-esteem...
June 1, 2017: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/28548291/practitioner-review-empirical-evolution-of-youth-psychotherapy-toward-transdiagnostic-approaches
#6
REVIEW
Lauren Krumholz Marchette, John R Weisz
BACKGROUND: Psychotherapy for children and adolescents (herein, 'youths') has grown more precise and focused over the decades, shifting toward empirically supported treatments standardized via therapist manuals. The manuals have increasingly emphasized precise targeting of single disorders or problems, or homogenous clusters. These focal treatments represent a valuable advance, with intervention benefit documented in hundreds of studies. However, relatively few of these treatments are widely used in everyday clinical practice, and their level of benefit may not be ideal, particularly in practice contexts and when compared to usual clinical care...
May 26, 2017: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/28543302/a-randomised-controlled-trial-of-an-ipad-based-application-to-complement-early-behavioural-intervention-in-autism-spectrum-disorder
#7
Andrew J O Whitehouse, Joanna Granich, Gail Alvares, Margherita Busacca, Matthew N Cooper, Alena Dass, Thi Duong, Rajes Harper, Wendy Marshall, Amanda Richdale, Tania Rodwell, David Trembath, Pratibha Vellanki, Dennis W Moore, Angelika Anderson
BACKGROUND: Technology-based interventions for Autism Spectrum Disorder (ASD) have proliferated, but few have been evaluated within the context of a randomised controlled trial (RCT). This RCT evaluated the efficacy of one technology-based early intervention programme (Therapy Outcomes By You; TOBY) in young children with ASD. METHODS: TOBY is an app-based learning curriculum designed for children and parents as a complement to early behavioural intervention. Eighty children (16 female) were recruited to this RCT within 12 months of receiving a diagnosis of ASD (M age = 3...
May 25, 2017: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/28542927/research-review-what-do-we-know-about-psychopathic-traits-in-children
#8
Randall T Salekin
BACKGROUND: Research on the topic of child psychopathy has advanced over the past decade increasing what we know. METHOD: This qualitative review examines the research base for child psychopathy and emphasizes its three dimensions: grandiose-manipulative, callous-unemotional, and daring-impulsive. Literature is reviewed addressing the cognitive, emotional, motivational, personality, parenting, and biological correlates. RESULTS: Support has emerged for the phenotypic construct of child psychopathy, while questions remain regarding definitional issues and key external correlates (e...
May 24, 2017: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/28543426/predictors-and-pathways-of-language-and-motor-development-in-four-prospective-cohorts-of-young-children-in-ghana-malawi-and-burkina-faso
#9
Elizabeth L Prado, Souheila Abbeddou, Seth Adu-Afarwuah, Mary Arimond, Per Ashorn, Ulla Ashorn, Jaden Bendabenda, Kenneth H Brown, Sonja Y Hess, Emma Kortekangas, Anna Lartey, Kenneth Maleta, Brietta M Oaks, Eugenia Ocansey, Harriet Okronipa, Jean Bosco Ouédraogo, Anna Pulakka, Jérôme W Somé, Christine P Stewart, Robert C Stewart, Stephen A Vosti, Elizabeth Yakes Jimenez, Kathryn G Dewey
BACKGROUND: Previous reviews have identified 44 risk factors for poor early child development (ECD) in low- and middle-income countries. Further understanding of their relative influence and pathways is needed to inform the design of interventions targeting ECD. METHODS: We conducted path analyses of factors associated with 18-month language and motor development in four prospective cohorts of children who participated in trials conducted as part of the International Lipid-Based Nutrient Supplements (iLiNS) Project in Ghana (n = 1,023), Malawi (n = 675 and 1,385), and Burkina Faso (n = 1,122)...
May 23, 2017: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/28543077/homotypic-and-heterotypic-continuity-of-symptoms-of-psychiatric-disorders-from-age-4-to-10%C3%A2-years-a-dynamic-panel-model
#10
Lars Wichstrøm, Jay Belsky, Silje Steinsbekk
BACKGROUND: Childhood psychiatric disorders and their symptoms evince both within-disorder (homotypic) and between-disorder (heterotypic) continuities. These continuities may be due to earlier symptoms causing later symptoms or, alternatively, that the same (unknown) causes (e.g., genetics) are operating across time. Applying a novel data analytic approach, we disentangle these two explanations. METHODS: Participants in a Norwegian community study were assessed biennially from 4 to 10 years of age with clinical interviews (n = 1,042)...
May 23, 2017: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/28524378/psychometric-characteristics-of-the-mental-health-crisis-assessment-scale-in-youth-with-autism-spectrum-disorder
#11
Luther G Kalb, Louis P Hagopian, Alden L Gross, Roma A Vasa
BACKGROUND: Youth with autism spectrum disorder (ASD) exhibit high rates of psychopathology. These symptoms can pose a risk of injury to self or others when the child is in crisis. Despite this danger, there are no instruments available to identify those with ASD who are at risk or actively in crisis. This study examined the psychometric properties of the Mental Health Crisis Assessment Scale (MCAS), a 28 item parent report measure. METHODS: The MCAS was administered to the parents of 606 children and young adults (aged 3-25 years, M age = 13 years, SD = 5 years) enrolled in the Interactive Autism Network, an online registry of families raising a child with ASD...
May 19, 2017: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/28524257/the-efficacy-of-early-language-intervention-in-mainstream-school-settings-a-randomized-controlled-trial
#12
Silke Fricke, Kelly Burgoyne, Claudine Bowyer-Crane, Maria Kyriacou, Alexandra Zosimidou, Liam Maxwell, Arne Lervåg, Margaret J Snowling, Charles Hulme
BACKGROUND: Oral language skills are a critical foundation for literacy and more generally for educational success. The current study shows that oral language skills can be improved by providing suitable additional help to children with language difficulties in the early stages of formal education. METHODS: We conducted a randomized controlled trial with 394 children in England, comparing a 30-week oral language intervention programme starting in nursery (N = 132) with a 20-week version of the same programme starting in Reception (N = 133)...
May 19, 2017: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/28524230/the-etiology-of-autistic-traits-in-preschoolers-a-population-based-twin-study
#13
Eveline L de Zeeuw, Catharina E M van Beijsterveldt, Rosa A Hoekstra, Meike Bartels, Dorret I Boomsma
BACKGROUND: Autism Spectrum Disorders (ASD) are highly heritable, but the exact etiological mechanisms underlying the condition are still unclear. METHODS: Using a multiple rater twin design in a large sample of general population preschool twins, this study aimed to (a) estimate the contribution of genetic and environmental factors to autistic traits, controlling for the possible effects of rater bias, (b) to explore possible sex differences in etiology and (c) to investigate the discordance in autistic traits in monozygotic and same-sex dizygotic twin pairs...
May 19, 2017: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/28512921/web-based-integrated-bipolar-parenting-intervention-for-parents-with-bipolar-disorder-a-randomised-controlled-pilot-trial
#14
Steven H Jones, Jelena Jovanoska, Rachel Calam, Laura D Wainwright, Helen Vincent, Ozgur Asar, Peter J Diggle, Rob Parker, Rita Long, Matthew Sanders, Fiona Lobban
BACKGROUND: People with bipolar disorder (BD) experience additional parenting challenges associated with mood driven fluctuations in communication, impulse control and motivation. This paper describes a novel web-based self-management approach (Integrated Bipolar Parenting Intervention; IBPI) to support parents with BD. METHOD: Parents with BD with children aged 3-10 years randomised to IBPI plus treatment as usual (TAU) or waitlist control (WL). IBPI offered 16 weeks access to interactive self-management information concerning BD and parenting issues...
May 16, 2017: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/28504358/randomized-controlled-trial-of-functional-family-therapy-for-offending-and-antisocial-behavior-in-uk-youth
#15
Sajid Humayun, Lauren Herlitz, Melanie Chesnokov, Moira Doolan, Sabine Landau, Stephen Scott
BACKGROUND: Youth offending and antisocial behavior (ASB) are associated with low quality mental health and relationships and usually lead to poor adult functioning; they are very costly for society. Family interventions are effective in children but there are few reliably effective and inexpensive interventions for adolescents. Functional Family Therapy (FFT) is an evidence-based intervention but seldom tested outside the United States. METHODS: One hundred and eleven adolescents (10-17 years of age, M = 15...
May 15, 2017: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/28504308/brainstem-as-a-developmental-gateway-to-social-attention
#16
Ronny Geva, Ayelet Dital, Dan Ramon, Jessica Yarmolovsky, Maor Gidron, Jacob Kuint
BACKGROUND: Evolution preserves social attention due to its key role in supporting survival. Humans are attracted to social cues from infancy, but the neurobiological mechanisms for the development of social attention are unknown. An evolutionary-based, vertical-hierarchical theoretical model of self-regulation suggests that neonatal brainstem inputs are key for the development of well-regulated social attention. METHODS: Neonates born preterm (N = 44, GA 34 w...
May 15, 2017: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/28504307/family-based-promotion-of-mental-health-in-children-affected-by-hiv-a-pilot-randomized-controlled-trial
#17
Theresa S Betancourt, Lauren C Ng, Catherine M Kirk, Robert T Brennan, William R Beardslee, Sara Stulac, Christine Mushashi, Estella Nduwimana, Sylvere Mukunzi, Beatha Nyirandagijimana, Godfrey Kalisa, Cyamatare F Rwabukwisi, Vincent Sezibera
BACKGROUND: Children affected by HIV are at risk for poor mental health. We conducted a pilot randomized controlled trial (RCT) of the Family Strengthening Intervention (FSI-HIV), a family home-visiting intervention to promote mental health and improve parent-child relationships in families with caregivers living with HIV, hypothesizing that child and family outcomes would be superior to usual care social work services. METHODS: Eighty two families (N = 170 children, 48...
May 15, 2017: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/28480579/longitudinal-epigenetic-predictors-of-amygdala-hippocampus-volume-ratio
#18
Esther Walton, Charlotte A M Cecil, Matthew Suderman, Jingyu Liu, Jessica A Turner, Vince Calhoun, Stefan Ehrlich, Caroline L Relton, Edward D Barker
BACKGROUND: The ratio between amygdala:hippocampal (AH) volume has been associated with multiple psychiatric problems, including anxiety and aggression. Yet, little is known about its biological underpinnings. Here, we used a methylome-wide approach to test (a) whether DNA methylation in early life (birth, age 7) prospectively associates with total AH volume ratio in early adulthood, and (b) whether significant DNA methylation markers are influenced by prenatal risk factors. METHODS: Analyses were based on a subsample (n = 109 males) from the Avon Longitudinal Study of Parents and Children, which included measures of prenatal risk, DNA methylation (Infinium Illumina 450k), T1-weighted brain scans and psychopathology in early adulthood (age 18-21)...
May 8, 2017: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/28474733/practitioner-review-the-effects-of-atypical-antipsychotics-and-mood-stabilisers-in-the-treatment-of-depressive-symptoms-in-paediatric-bipolar-disorder
#19
REVIEW
Tobias Atkin, Nicolas Nuñez, Gabriella Gobbi
BACKGROUND: The management of depressive and mixed symptoms in children and adolescents with bipolar disorder (BD) remains a matter of debate. The goal of this review is, thus, to systematically examine the impact of atypical antipsychotics (AAPs) and mood stabilisers in the treatment of bipolar depression and/or mixed states. METHODS: A literature search was conducted for studies assessing the efficacy of pharmacological treatments for bipolar disorder type I, type II and not otherwise specified with a recent depressive, mixed or manic episode (with depressive symptoms) following DSM-IV criteria in children and adolescents as either acute or maintenance treatment...
May 5, 2017: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/28464350/development-and-validation-of-an-item-response-theory-based-social-responsiveness-scale-short-form
#20
Alexandra Sturm, Megan Kuhfeld, Connie Kasari, James T McCracken
BACKGROUND: Research and practice in autism spectrum disorder (ASD) rely on quantitative measures, such as the Social Responsiveness Scale (SRS), for characterization and diagnosis. Like many ASD diagnostic measures, SRS scores are influenced by factors unrelated to ASD core features. This study further interrogates the psychometric properties of the SRS using item response theory (IRT), and demonstrates a strategy to create a psychometrically sound short form by applying IRT results...
May 2, 2017: Journal of Child Psychology and Psychiatry, and Allied Disciplines
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