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Indian Journal of Physiology and Pharmacology

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https://www.readbyqxmd.com/read/29957989/enteric-glial-cells-and-inflammatory-bowel-disease-friend-or-foe
#1
Purnima Sharma
No abstract text is available yet for this article.
July 2016: Indian Journal of Physiology and Pharmacology
https://www.readbyqxmd.com/read/29957988/high-steroid-usage-among-reproductive-aged-farmers-in-underserved-area-in-indonesia-langkat-south-securai-village
#2
LETTER
Sarma Nursani Lumbanraja
No abstract text is available yet for this article.
July 2016: Indian Journal of Physiology and Pharmacology
https://www.readbyqxmd.com/read/29957987/endocrinology-coverage-in-the-haryana-eml-essential-medicines-list
#3
LETTER
Garima Bhutani, Sanjay Kalra, Prem Kumar Verma
No abstract text is available yet for this article.
July 2016: Indian Journal of Physiology and Pharmacology
https://www.readbyqxmd.com/read/29957986/electrolyte-abnormalities-in-cisplatin-based-chemotherapy
#4
LETTER
S Nikhil, Araavindh S Anand
No abstract text is available yet for this article.
July 2016: Indian Journal of Physiology and Pharmacology
https://www.readbyqxmd.com/read/29957985/perceptions-of-post-graduate-students-towards-m-d-physiology-curriculum-in-india
#5
Noorin Bhimani, Priyadarshini Mishra
In India, the system of postgraduate (PG) medical education has suffered due to long-term neglect. A comprehensive review of the curriculum of PG courses has not taken place for several decades. Whatever changes have been made are marginal and have had little overall impact. Inspite of societal need and dearth of physiologist, there is an observation that there hardly any takers for M.D. Physiology. The above facts compel the need into rethinking the training and curriculum designing of M.D. Physiology curriculum in India...
July 2016: Indian Journal of Physiology and Pharmacology
https://www.readbyqxmd.com/read/29957984/pharmacological-interventions-for-vascular-targeting-in-retinopathy-of-prematurity-an-experimental-study
#6
Neelima Aron, Madhu Nath, Shorya Vardhan Azad, Parijat Chandra, Raj Vardhan Azad, Thirumurthy Velpandian
Purpose: This study was conducted to evaluate the pharmacological interventions to target vascular proliferation in the Retinopathy of Prematurity (ROP). Methods: Protein Kinase C modulator (Bryostatin), tubulin polymerization inhibitor (Dolastatin 10), antiVEGF (Bevacizumab) and a non-specific VEGF inhibitor (Thalidomide) were screened in Retinopathy of Prematurity (ROP) model. The retinal vasculature was evaluated by calculating the tortuosity indices of vessels and electroretinography responses in terms of ‘b’ wave amplitude and was recorded from ROP rats on postnatal Day 17 and Day 25...
July 2016: Indian Journal of Physiology and Pharmacology
https://www.readbyqxmd.com/read/29957983/evaluation-of-the-protective-effect-of-nmda-non-nmda-receptor-antagonists-against-ethambutol-induced-retinal-toxicity-using-erg-in-wistar-rats
#7
A R Vijayakumar, H Anuradha, Nihar Ranjan Biswas, Vimla Menon, Rohit Saxena, Nabanita Halder, T Velpandian
To study the protective effect of NMDA and non-NMDA receptor antagonists against ethambutol (EMB) induced retinal toxicity in Wistar rats using flash electroretinogram (ERG). Rats were randomized into four groups: Group-1 received vehicle. Group-2 received oral EMB (200 mg/kg/day). Group-3 and 4 were fed with oral EMB along with memantine (MEM) (1 mg/kg, ip) and trimetazidine (TMZ) (3mg/kg, ip) respectively. All treatments were continued up to 28 days. ERG was recorded at 0 and 21st day using green and white lights...
July 2016: Indian Journal of Physiology and Pharmacology
https://www.readbyqxmd.com/read/29957920/sub-clinical-hypothyroidism-in-type-2-diabetes-mellitus-patients-in-a-tertiary-care-hospital-mysore
#8
Srinath C Galag, R Rajalashmi, K M Srinath, B Madhu
Thyroid diseases and type 2 diabetes mellitus are the two most common endocrine disorders encountered in clinical practice. Diabetes mellitus and thyroid disorders are shown to mutually influence each other. The present study was done to assess and compare the thyroid function tests in diabetes mellitus patients and normal healthy volunteers. This is a cross-sectional, age-matched, comparative, hospital based study. Type 2 Diabetes mellitus patients without hypothyroidism attending the medicine outpatient department (OPD) or admitted in the medicine wards were screened and then included as cases (30 patients)...
July 2016: Indian Journal of Physiology and Pharmacology
https://www.readbyqxmd.com/read/29957917/comparison-of-cardiovascular-parameters-and-cardiac-autonomic-activity-of-obese-and-normal-weight-school-children-in-puducherry
#9
R Rajalakshmi, Susheela Veliath, N Krishnamurthy, M Thenmozhi
Background and Aim: Worldwide, incidence of childhood obesity is on the rising trend and obese children are more vulnerable to various health disorders. This study was done to assess and compare the cardiovascular parameters and Heart rate variability (HRV) parameters of obese school children with children with normal Body Mass Index (BMI). Methods: Thirty obese children (BMI  95th percentile) aged 9-12 years and 30 age and sex matched children with normal BMI (BMI 5th to below 85th percentile) were included in test and control groups respectively...
July 2016: Indian Journal of Physiology and Pharmacology
https://www.readbyqxmd.com/read/29957914/correlation-of-audio-visual-reaction-time-with-body-mass-index-skin-fold-thickness-between-runners-and-healthy-controls
#10
S Jyothi, Sunil S Vernekar, Manishankar, L Jayalakshmi Vinothkumar, R Rashmi
Audio-visual reaction time is essential for activities like driving and very important in sports persons. Reaction time of 31 National level runners was compared with 31 controls. Runners were subdivided into two groups, group A (>2 yrs & < 3 yrs of training) and group B (>3 yrs & < 10 yrs of training). Correlation between Body Mass Index & Skin Fold Thickness with reaction time was also analyzed. Reaction time was significantly less in runners (p<0.05) when compared to controls and also in group B...
July 2016: Indian Journal of Physiology and Pharmacology
https://www.readbyqxmd.com/read/29957912/hindi-and-english-letter-cancellation-tasks-does-language-have-an-effect-on-performance
#11
Abhinav Dixit, Ankit Kumar Rai
Letter Cancellation Tasks (LCTs) are paper-pencil based psychomotor tasks that are commonly used to assess cognitive functions of healthy volunteers and patients. The performance on LCTs can be affected by the proficiency in the language used for the tasks. This is of importance in a country like India where most of the population is not fluent in English. Since most of the cognitive tests are in English, the population that can be recruited for cognitive studies gets limited. It is therefore essential to develop tests in Indian languages like Hindi and compare the results obtained with tests in English...
July 2016: Indian Journal of Physiology and Pharmacology
https://www.readbyqxmd.com/read/29957910/do-congenitally-blind-individuals-have-better-haptic-object-perception-compared-to-blindfolded-sighted-individuals
#12
B G Bhirud, L M Chandan, A Chawla
Objective: Haptic perceptual enhancement in congenitally blind people is a subject of intense debate. There is no consensus whether the congenitally blind get the benefit of their haptic experience or the sighted get the benefit of previous visual experience when it comes to recognizing objects by manual exploration using different constraints. The present study compared haptic object perception between congenitally blind and blindfolded sighted participants in a situation where manual exploration of objects was constrained...
July 2016: Indian Journal of Physiology and Pharmacology
https://www.readbyqxmd.com/read/29957906/cardiac-autonomic-neuropathy-in-type-ii-diabetes-mellitus-patients-and-its-association-with-the-age-of-the-patient-duration-of-disease-and-glycemic-control
#13
V Nagalakshmi, V Smruthi, Shama, Gauthan Rathnakarashetty, Shobha C Nallulwar
Objectives: Evaluation of association between age, duration of disease and glycemic control in type II diabetics with the incidence of cardiac autonomic neuropathy (CAN). Methods: Study includes 50 Type II diabetic patients of 40-60 years age of both the genders with different duration of disease. CAN was evaluated in terms of presence of resting tachycardia, loss of sinus arrhythmia and heart rate response to Valsalva maneuver by electrocardiogram (ECG). An R-R variation with respiration of >15 beats per minute was taken normal, while 10-15 beats and <10 beats per minute were taken as borderline and definitive CAN respectively...
July 2016: Indian Journal of Physiology and Pharmacology
https://www.readbyqxmd.com/read/29957904/a-novel-practical-to-demonstrate-systemic-and-local-regulation-of-circulation-in-a-human-subject
#14
Manpreet Kaur, Dinu S Chandran, Ashok K Jaryal, Kishore K Deepak
Purpose of the study: Systemic and local regulation of peripheral circulation is a vital concept to be taught to undergraduate medical students. There is lack of an effective practical module to demonstrate and reinforce the theoretical understanding of this concept. Methodology: We designed a simple feasible novel practical using finger pulse recording coupled with hand grip test and reactive hyperemia protocol to elicit systemic and local regulation of peripheral circulation respectively...
July 2016: Indian Journal of Physiology and Pharmacology
https://www.readbyqxmd.com/read/29809381/an-evidence-based-study-on-comparison-of-adverse-drug-reactions-of-metformin-sitagliptin-with-their-combination
#15
LETTER
Krunal Dalal, Alpa Gor, Barna Ganguly
No abstract text is available yet for this article.
April 2016: Indian Journal of Physiology and Pharmacology
https://www.readbyqxmd.com/read/29809380/comparison-of-anthropometric-parameters-and-blood-pressure-changes-in-response-to-physical-stress-test-in-normotensive-subjects-with-or-without-family-history-of-hypertension
#16
Amita M Pardeshi, Sunanda N Kirtikar
Hypertension is recognized as a key risk factor for cardiovascular disease mortality and morbidity. Early detection of prehypertensive stage may help an individual to lead a healthy life by altering the life style. The present study was attempted to compare blood pressure response and anthropometric parameter in children of hypertensive and non hypertensive parents. The study was conducted on total 120 participants, 60 in control and 60 in test group. Cardiovascular response to stress was determined by Harvard step test...
April 2016: Indian Journal of Physiology and Pharmacology
https://www.readbyqxmd.com/read/29809379/effect-of-ascorbic-acid-on-interleukin-2-secretion-by-t-lymphocytes-in-whole-blood-cultures
#17
Snekalatha S
The effect of vitamin C on T lymphocyte function is not clear. In-vivo supplementation of vitamin C is found to have a stimulatory effect on T cells while studies in which ascorbic acid was added to T cell cultures show an inhibition of cell function. The study aims to investigate the effect of ascorbic acid on interleukin-2 secretion by T cells in whole blood cultures which better resembles the physiological environment than pure T cell cultures. It was found that ascorbic acid, when added to whole blood cultures at a very high concentration of 1 mM, inhibits interleukin-2 secretion by T cells (p<0...
April 2016: Indian Journal of Physiology and Pharmacology
https://www.readbyqxmd.com/read/29809378/description-and-validation-of-a-novel-method-of-measuring-pharyngeal-pressure-in-new-born
#18
Nishanth Sampath, Akanksha Singh, Shridhar Gopalakrishnan, Anu Thukral, M Jeeva Sankar, Ramesh Agarwal, Ashok Kumar Jaryal, Ashok Deorari, Vinod K Paul
Study background: Measurement of delivered pharyngeal pressure during continuous positive airway pressure (CPAP) therapy is not in routine practice due to lack of a simple and affordable technique of intrapharyngeal pressure measurement. To overcome the lack of the gold standard solid-state catheter-tip pressure measurement technology in our set up, we improvised a novel method of pressure measurement and tested its validity in a simulated pharynx. METHODS: A low-cost pressure transducer was improvised by attaching an orogastric tube to its one end...
April 2016: Indian Journal of Physiology and Pharmacology
https://www.readbyqxmd.com/read/29809377/olanzapine-vs-risperidone-in-schizophrenia-a-cross-sectional-comparison-of-quality-of-life-of-caregivers
#19
COMPARATIVE STUDY
Meghaa S Bhargava, Harmeet Singh Rehan, Dinesh Kataria
In schizophrenia, efficacy of antipsychotic therapy might be better measured by quality of life (QoL) of caregiver, due to less reliability of patient's account and greater burden of management on caregiver. Hence, we compared QoL of the primary caregiver of schizophrenics prescribed either olanzapine or risperidone. In a cross sectional analytical study, caregivers of 120 schizophrenic patients' on either olanzapine or risperidone filled the WHOQOL-BREF questionnaire containing physical, psychological, social and environmental domains...
April 2016: Indian Journal of Physiology and Pharmacology
https://www.readbyqxmd.com/read/29809376/fabrication-and-validation-of-gyro-dot-optomotor-response-device-using-gold-fish-to-study-drugs-affecting-visual-perception
#20
Arumugam Ramamoorthy Vijayakumar, Nihar Ranjan Biswas, Vimla Menon, Rohit Saxena, Warisha Ahmed, Nabanita Halder, Thirumurthy Velpandian
An appropriate model to predict the effect of xenobiotics on the vision perception in neuropsychoharmacological studies is of great importance in drug development and toxicity studies. The present study valuated the effect of CNS stimulant, depressant and therapeutic agents known to have ocular toxicity on ptomotor response (OMR) using goldfish in a newly developed device. A digital light processing aided gyrating poly-chromatic dotted pattern-OMR (Gyro-dot-OMR) analyzer was developed and standardized for this study in our laboratory...
April 2016: Indian Journal of Physiology and Pharmacology
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