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Indian Journal of Physiology and Pharmacology

Sabyasachi Sircar
No abstract text is available yet for this article.
October 2015: Indian Journal of Physiology and Pharmacology
Madhuri Taranikanti, Nikhat Yasmeen, Sanghamitra Panda, Ratna Jyothi Meka, Jayalakshmi Behara, Abdul Raoof Omer Siddiqui
UNLABELLED: Hemostatic system is designed to maintain blood in a fluid state yet provide important defenses against bleeding when injury occurs to the vessel. During surgery, patients are exposed to hemostatic stress causing complications of either hypercoagulability or hemorrhage. The goal of the present study was to describe the clotting changes in patients who underwent major surgeries especially procoagulant mechanisms. METHODS: 30 patients belonging to both sexes who were undergoing surgery for various reasons were included in the study...
October 2015: Indian Journal of Physiology and Pharmacology
Rajiv Rastogi, Priti Bendore
BACKGROUND: Cervical spondylosis is a degenerative disease of cervical spine. The conventional management offered in this condition focuses upon pain, muscle relaxation and restoration of movements. This approach however has not been found adequate in many cases. CASE CHARACTERISTICS: This is a case of cervical spondylosis treated with naturopathy and yogic practices in an OP set up. Earlier to this treatment, the patient was on conventional medicine. INTERVENTION: The patient was given naturopathy treatments in form of cold spinal pack followed by other procedures and some yogic practices consisting of asanas, pranayam and relaxation for 30 minutes for a period of one month with an improvement in symptoms...
October 2015: Indian Journal of Physiology and Pharmacology
Kumar Sai Sailesh, J K Mukkadan
The present study was designed to standardize optimal vestibular stimulation and to investigate its impact on anxiety levels in college students. Vestibular stimulation was achieved by swinging on a swing (Back to front direction) and the participants were advised to adjust frequency, duration and intensity, according to comfort. Frequency, intensity and duration were recorded manually. The anxiety status was assessed by using Spielberger state-trait anxiety inventory (STAI) before and after vestibular stimulation...
October 2015: Indian Journal of Physiology and Pharmacology
Kishore K Deepak, Khalid Umran Al-Umran, Mona H AI-Sheikh, B V Dkoli, Abdullah Al-Rubaish
OBJECTIVES: The functionality of distracters in a multiple choice question plays a very important role. We examined the frequency and impact of functioning and non-functioning distracters on psychometric properties of 5-option items in clinical disciplines. METHODS: We analyzed item statistics of 1115 multiple choice questions from 15 summative assessments of undergraduate medical students and classified the items into five groups by their number of non-functioning distracters...
October 2015: Indian Journal of Physiology and Pharmacology
Vani Gupta, Sameeksha Mishra, Sandeep Kumar, Supriya Mishra
The present study was designed to investigate the association between circulating Orexin-A level with metabolic risk factors in North Indian adult women. 342 women were enrolled for the case-control study, 172 women were with metabolic syndrome (mets) and 170 healthy control women were without metabolic syndrome, (womets) according to (NCEP ATP III criteria). Circulating Orexin-A level was determined by enzyme-linked immunosorbent assay. Observations indicated low levels of orexin-A (26.06 ± 6.09 ng/ml) in women with mets and other metabolic risk factors compared to women without metabolic syndrome (36...
October 2015: Indian Journal of Physiology and Pharmacology
Yogesh Singh, Ratna Sharma
OBJECTIVES: To explore the EEG changes associated with psychological stress state. METHODS: The study was conducted on 34 healthy male student volunteers. The intervention consisted of psychological stress, which was induced by asking the participants to play a pre-decided stressful computer game. Physiological markers of psychological stress were assessed using galvanic skin response (GSR) and heart rate (HR). Electroencephalography (EEG) was recorded from 19 scalp locations according to 10-20 international system of electrode placement...
October 2015: Indian Journal of Physiology and Pharmacology
Rajesh Jeniton Fernando, K Ravichandran, Mario Vaz
Data on aerobic fitness and heart rate recovery in children are limited. This study was done to evaluate the relation between them in Indian school going children. Three hundred children of 7 to 10.5 years were recruited and their aerobic fitness was predicted using modified Harvard's step test (VO₂max) and 20 meter shuttle test (VO₂peak). The heart rate was monitored for 12 minutes post modified Harvard's step test. The difference between the maximum and the 1st minute HR was noted as HRR1 and the time taken to reach the resting heart rate was also recorded...
October 2015: Indian Journal of Physiology and Pharmacology
K Singh
Mobile phone (MP) is commonly used communication tool. Electromagnetic waves (EMWs) emitted from MP may have potential health hazards. So, it was planned to study the effect of electromagnetic waves (EMWs) emitted from the mobile phone on brainstem auditory evoked potential (BAEP) in male subjects in the age group of 20-40 years. BAEPs were recorded using standard method of 10-20 system of electrode placement and sound click stimuli of specified intensity, duration and frequency.Right ear was exposed to EMW emitted from MP for about 10 min...
October 2015: Indian Journal of Physiology and Pharmacology
Jyotsana R Bharshankar, Archana D Mandape, Mrunal S Phatak, Rajay N Bharshankar
Stress, an inevitable and constant feature throughout the lifetime, induces autonomic dysfunctions, for which meditation is considered to be an antidote. So the case control study was planned including 50 Raja-yoga meditators practicing meditation for 5 years and 50 age matched non-meditators. Autonomic function tests were performed and results were compared using the Student-t test. Mean values of resting HR, SBP and DBP were less in meditators. Galvanic Skin Response in meditators was significantly more (p < 0...
October 2015: Indian Journal of Physiology and Pharmacology
Suranjana Sur Mukherjee, M V Sawane, P A Nikose
OBJECTIVE: This cross-sectional comparative study tried to assess the hearing status of the high risk infants by Brainstem Evoked Response Audiometry (BERA) and compare with that of the normal infants. MATERIAL & METHODS: BERA was done on 127 infants of 6 to 18 months age of which 87 were high risk. All were given monaural acoustic stimulation using Cz-M₁/M₂ Montage. Waves I, III and V were analysed for absolute & interpeak latencies (in ms) & also for amplitudes (in µv) & their ratio...
October 2015: Indian Journal of Physiology and Pharmacology
Rosemary Peter, Sushma Sood, Ashwani Dhawan
Physical inactivity is an important risk factor for cardiovascular mortality and morbidity. Exercise is considered an acceptable method for improving and maintaining physical and emotional health. Although yoga is historically a spiritual discipline, a growing body of evidence supports the belief that yoga benefits physical and mental health. The objective of this study was to evaluate heart rate variability which reflects autonomic control of heart among yoga practitioners, athletes and individuals with sedentary lifestyle...
October 2015: Indian Journal of Physiology and Pharmacology
Modou Oumy Kane, Mbaye Sene, Eric Anselm, Stéphanie Dal, Valérie B Schini-Kerth, Cyril Augier
BACKGROUND: Several epidemiological studies have shown that regular consumption of moderate amounts of wine, in particular red wine, is associated with a decreased total mortality due, in part, to a reduced risk of cardiovascular diseases. The protective effect has been attributable to polyphenols, which are potent vasodilators and have anti-thrombotic properties. Polyphenols have been shown to induce pronounced endothelium-dependent relaxations of arteries by causing the redox-sensitive PI3-kinase-dependent formation of nitric oxide (NO) and endothelium-derived hyperpolarizing factor (EDHF)...
October 2015: Indian Journal of Physiology and Pharmacology
Anna Zemancíková, Jozef Török
BACKGROUND: Hypertensive rats serve as valuable tools for studies of dysregulations in cardiovascular functions before and during pathological elevation of blood pressure. They exhibit many defects in structure and function of heart and vessels which are often related to severity of hypertension. OBJECTIVE: The relationship of blood pressure level and manifestation of aberrations in selected cardiovascular and metabolic parameters were determined in 20-week-old normotensive Wistar-Kyoto (WKY) rats, spontaneously hypertensive rats (SHR) and in their F1 offspring borderline hypertensive rats (BHR), and also in normotensive Wistar rats which are genetically less compatible with the other mentioned rat strains...
October 2015: Indian Journal of Physiology and Pharmacology
Sabyasachi Sircar
No abstract text is available yet for this article.
October 2015: Indian Journal of Physiology and Pharmacology
Kamlesh Sharma, Asha Gandhi, Himani Ahluwalia, J K Sahni
Declining hearing sensitivity is appreciated as a normal age related change. However, studies reveal that health variables other than age play significant role in hearing impairment over time. Hypertension is one such variable. The objective of this study was to assess whether the hypertension has an accelerating effect on age related reduction in hearing function in males in the age group of 40-60 years. Systolic and Diastolic blood. pressure and Pure Tone thresholds in frequency range 250-8000 Hz were measured in 30 known hypertensive (HT) male subjects in the age group of 40-60 years and 30 age and sex-matched normotensive (NT) controls...
April 2015: Indian Journal of Physiology and Pharmacology
Raj Kapoor, V K Roy, S Manna, M Bhattacharjee
Measurement of blood pressure is an integral part of clinical examination. Over the years various types of instruments have been used to measure blood pressure but till date the mercury sphygmomanometer is regarded as the gold standard. However, there is a myth prevalent among health professionals regarding the level of the manometer in relation to heart at the time of measuring of blood pressure. Many professionals insist that it has to be placed at the level of the heart. We argue that the limb from which pressure is measured must be at the heart level rather than the manometer...
April 2015: Indian Journal of Physiology and Pharmacology
Komal Marwaha, Anumeha Bhagat, Nandini Kapoor
This study was undertaken to determine the learning style preferences of first and 2nd year BDS students by administering VARK questionnaire. Stepping stone method was used to identify sensory modality preference of each student. 51% students preferred single mode of learning style (27% kinesthetic, 15% aural, 6% read/write and 3% visual mode of learning style). 49% students preferred multiple modes (23% bi-modal, 17% tri-modal, 9% had quad-modal preference). The mean V, A, R, K scores were determined and compared using Mann-Whitney U test...
April 2015: Indian Journal of Physiology and Pharmacology
Mousa-Al-Reza Hadjzadeh, Ziba Rajaei, Reyhaneh Moradi, Ahmad Ghorbani
OBJECTIVE: Hyperlipidemia is a known complication of diabetes mellitus and predisposes to coronary heart disease. The lowering of total cholesterol and low density lipoprotein (LDL)-cholesterol should reduce the incidence of coronary disease. The aim of the present study was to examine the antihyperlipidemic and antidiabetic effects of the hydroalcoholic extract of watercress (Nasturtium officinale) leaves in streptozotocin-induced diabetic rats. METHODS: Female Wistar rats were randomly divided into 4 groups: control, diabetic and diabetic rats treated with the extract of watercress (Nasturtium officinale) at doses of 100 and 200 mg/kg...
April 2015: Indian Journal of Physiology and Pharmacology
Shinichiro Kawaguchi, Rika Kuwahara, Yumi Kohara, Yutaro Uchida, Yushi Oku, Kimihiro Yamashita
4-Nonylphenol (NP) has weak estrogen-like activity, and can therefore act as an endocrine disruptor. This study examined the effects of perinatal exposure to low-dose NP on learning and memory, general activity, and emotionality in male rat offspring. Dams were orally administered 1 or 10 mg/kg/day of NP or vehicle from gestational day 10 to postnatal day 14. The male offspring were evaluated using a battery of behavioral tests, including an appetite-motivated maze test (MAZE test) used to assess spatial learning and memory...
April 2015: Indian Journal of Physiology and Pharmacology
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