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Indian Journal of Medical Research

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https://www.readbyqxmd.com/read/27834341/zosteriform-type-in-transit-metastasis-of-melanoma
#1
Faruk Tas
No abstract text is available yet for this article.
July 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/27834340/acro-osteolysis-calcinosis-in-scleroderma
#2
Sujith V Cherian, Elena Thampy
No abstract text is available yet for this article.
July 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/27834339/scrub-typhus-in-hilly-regions-of-north-east-india
#3
LETTER
Siraj A Khan, Vinotsole Khamo, Helen J Uriah, Trishna Bora, Prafulla Dutta
No abstract text is available yet for this article.
July 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/27834338/hair-dye-poisoning-retrospective-analyses-of-patients-admitted-to-icu-at-a-rural-hospital-in-india
#4
LETTER
Laura Sanchez, Harish Handyal, Shanmugamari Kannan, Gerardo Alvarez-Uria, Laura Gavalda, Xavier Corbella
No abstract text is available yet for this article.
July 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/27834337/a-novel-indirect-elisa-for-diagnosis-of-dengue-fever
#5
Rohan Narayan, Senthil Raja, Senthil Kumar, Mohana Sambasivam, Raja Jagadeesan, Kavita Arunagiri, Kaveri Krishnasamy, Gunasekaran Palani
BACKGROUND & OBJECTIVES: Dengue fever (DF) is associated with significant morbidity and mortality in the tropical and sub-tropical regions of the world. Since there are no effective antiviral drugs for treatment, clinicians often rely on the accurate diagnosis of dengue fever to begin supportive therapy at early stages of the illness. The objective of this study was to develop an in-house dengue virus serotype 2 (DENV-2) non-structural protein- 5 (NS5) based indirect ELISA. METHODS: DENV-2 was raised in Vero cells and the viral proteins were separated and subsequently the NS5 protein was eluted...
July 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/27834336/evaluation-of-symptoms-spirometry-in-children-treated-for-asthma
#6
Shobi Anandi, Milind S Tullu, Keya Lahiri
BACKGROUND & OBJECTIVES: Spirometry plays an important role in the assessment and long term monitoring of patients with asthma. Difficulty in performing spirometry in children has resulted in a paucity of Indian studies using spirometry regularly for research in the paediatric population. This study was undertaken to assess the clinical improvement and changes in spirometric measurements with treatment in children with newly diagnosed asthma and to compare the changes in the symptom score and spirometric measurements...
July 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/27834335/a-pcr-rflp-method-for-detection-of-the-lnpep-encoding-human-insulin-regulated-aminopeptidase-irap-rs4869317-polymorphism
#7
MarIa Jesús RamIrez-Expósito, Jos Manuel MartInez-Martos, Teresa Palomeque, Pedro Lorite
BACKGROUND & OBJECTIVES: Insulin regulated aminopeptidase (IRAP) has been related to certain pathologies such as breast cancer, Alzheimer΄s disease and septic shock. IRAP is encoded by the leucyl/cystinyl aminopeptidase (LNPEP) gene. The genetic variation in the LNPEP gene has been analyzed in relation with the mortality and vasopressin clearance in septic shock. The LNPEP rs4869317 SNP (single nucleotide polymorphism) was the most significantly associated SNP with vasopressinase activity, being TT genotype associated with increased mortality...
July 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/27834334/comparison-of-dietary-profile-of-a-rural-south-indian-population-with-the-current-dietary-recommendations-for-prevention-of-non-communicable-diseases-cures-147
#8
Narasimhan Sowmya, Nagarajan Lakshmipriya, Kokila Arumugam, Sivasankari Venkatachalam, Parthasarathy Vijayalakshmi, Vaidya Ruchi, Gunasekaran Geetha, Ranjit Mohan Anjana, Viswanathan Mohan, Kamala Krishnaswamy, Vasudevan Sudha
BACKGROUND & OBJECTIVES: Despite the rising prevalence of non-communicable diseases (NCDs) in rural India, data on the dietary profile of the rural Indian population in relation to the recommendations for prevention of NCDs are scarce. This study was conducted to assess the dietary intake of a rural south Indian population in relation to the current dietary recommendations for the prevention of NCDs. METHODS: The dietary profiles of 6907 adults aged ≥ 20 yr, from a cluster of 42 villages in Kancheepuram district of Tamil Nadu State in southern India, were assessed using a validated food frequency questionnaire...
July 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/27834333/effect-of-lamotrigine-levetiracetam-topiramate-on-neurobehavioural-parameters-oxidative-stress-in-comparison-with-valproate-in-rats
#9
Sudhir Chandra Sarangi, Ashish Kumar Kakkar, Ritesh Kumar, Yogendra Kumar Gupta
BACKGROUND & OBJECTIVES: Though newer antiepileptic drugs are considered safer than conventional antiepileptics, the effects of lamotrigine, levetiracetam and topiramate on neurobehavioural functions are yet to be established. This study evaluated neurobehavioural parameters and oxidative stress markers in brain tissue of rats treated with lamotrigine, levetiracetam and topiramate compared to sodium valproate . METHODS: Five groups of male Wistar rats were treated respectively with normal saline (control), sodium valproate (370 mg/kg), lamotrigine (50 mg/kg), levetiracetam (310 mg/kg) and topiramate (100 mg/kg) for 45 days...
July 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/27834332/attenuation-of-quorum-sensing-regulated-behaviour-by-tinospora-cordifolia-extract-identification-of-its-active-constituents
#10
Viraj C Gala, Nithya R John, Ashok M Bhagwat, Ajit G Datar, Prashant S Kharkar, Krutika B Desai
BACKGROUND & OBJECTIVES: The pathogenicity of the nosocomial pathogens, Pseudomonas aeruginosa and Acinetobacter baumannii is regulated by their quorum sensing (QS) systems. The objective of the present study was to examine the effect of the cold ethyl acetate extract of Tinospora cordifolia stem on virulence and biofilm development in the wild type and clinical strains of P. aeruginosa and A. baumannii. The study was further aimed to identify the probable active constituents in the plant extract...
July 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/27834331/evaluation-of-colorimetric-nitrate-reductase-assay-for-rapid-detection-of-methicillin-resistance-in-clinical-isolates-of-staphylococcus-aureus
#11
N Niveditha, Sujatha Sistla
BACKGROUND & OBJECTIVES: Methicillin resistant Staphylococcus aureus (MRSA) remains a major cause of health care-associated infections. Rapid detection of MRSA facilitates the early initiation of appropriate treatment and infection control. Hence, the present study was undertaken to standardize and evaluate the performance of rapid colorimetric nitrate reductase assay (NRA) for determining methicillin resistance in S.aureus. METHODS: A total of 160 clinical isolates of S...
July 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/27834330/distribution-trends-antibiogram-pattern-of-salmonella-enterica-serovar-newport-in-india
#12
Y Kumar, N Gupta, V B Vaish, S Gupta
BACKGROUND & OBJECTIVES: Salmonellosis is a major public health concern worldwide. Besides typhoidal salmonellae, infections due to non-typhoidal serovars of Salmonella are also associated with high morbidity and mortality leading to huge economic losses. Among non-typhoidal serovars, Salmonella Newport has been reported as a major cause of foodborne infections resulting in outbreaks due to consumption of contaminated food items. Little data related to this serovar are available from India leading to the scarcity of information on the distribution trends of this important serovar in the country...
July 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/27834329/epidemiology-risk-factors-of-scrub-typhus-in-south-india
#13
George M Varghese, Deepa Raj, Mark R Francis, Rajiv Sarkar, Paul Trowbridge, Jayaprakash Muliyil
BACKGROUND & OBJECTIVES: Scrub typhus is a major public health threat in South and Southeastern Asian countries including India. Understanding local patterns of disease and factors that place individuals at risk is pivotal to future preventive measures against scrub typhus. The primary aim of this study was to identify specific epidemiological and geographical factors associated with an increased risk of developing scrub typhus in this region. METHODS: We mapped 709 patients from Tamil Nadu, Andhra Pradesh and Telangana who were admitted to the Christian Medical College (CMC) Hospital, Vellore, Tamil Nadu, India, for the period 2006-2011, assessed seasonality using monthly counts of scrub typhus cases, and conducted a case-control study among a subset of patients residing in Vellore...
July 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/27834328/intricacies-of-using-temperature-of-different-niches-for-assessing-impact-on-malaria-transmission
#14
Poonam Singh, Yogesh Yadav, Shweta Saraswat, Ramesh C Dhiman
BACKGROUND & OBJECTIVES: The influence of temperature on the life cycle of mosquitoes as well as on development of malaria parasite in mosquitoes is well studied. Most of the studies use outdoor temperature for understanding the transmission dynamics and providing projections of malaria. As the mosquitoes breed in water and rest usually indoors, it is logical to relate the transmission dynamics with temperature of micro-niche. The present study was, therefore, undertaken to understand the influence of different formats of temperature of different micro-niches on transmission of malaria for providing more realistic projections...
July 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/27834327/factors-associated-with-utilization-of-antenatal-care-services-among-tribal-women-a-study-of-selected-states
#15
Tulsi Adhikari, Damodar Sahu, Saritha Nair, Kalyan B Saha, Ravendra K Sharma, Arvind Pandey
BACKGROUND & OBJECTIVES: Despite various efforts by the Government of India, utilization of antenatal care (ANC) services continues to be low among women from rural areas particularly those belonging to the Scheduled Tribes. The present study was undertaken to examine the factors associated with the utilization of ANC services among women in four States including Rajasthan, Odisha, Chhattisgarh and Madhya Pradesh which constitute a good share of tribal population of the country. METHODS: Data from third round of District Level Household and Facility Survey, 2007-08 (DLHS-3) have been used...
July 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/27834326/validation-of-icmr-index-for-identification-of-dental-fluorosis-in-epidemiological-studies
#16
Ashima Goyal, Mahesh Verma, G S Toteja, K Gauba, Vikrant Mohanty, Utkal Mohanty, Rupinder Kaur
BACKGROUND & OBJECTIVES: The Indian Council of Medical Research (ICMR) formulated a Task Force on dental fluorosis and recommended the subgroup to develop a simplified index for identification and grading of dental fluorosis to be used by the health workers. This study was conducted to pre-test the 'ICMR Index for Dental Fluorosis' in the field to check its reliability and reproducibility. METHODS: A total of 600 photographs were taken, 150 in each grade of fluorosis by screening 14-17 yr school children from eight schools of Hisar (Haryana) and South west Delhi...
July 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/27834325/lack-of-association-between-foki-polymorphism-in-vitamin-d-receptor-gene-vdr-type-2-diabetes-mellitus-in-the-tunisian-population
#17
Imen Mahjoubi, Amani Kallel, Mohamed Hédi Sbaï, Bochra Ftouhi, Meriam Ben Halima, Zeineb Jemaa, Moncef Feki, Hedia Slimane, Riadh Jemaa, Naziha Kaabachi
BACKGROUND & OBJECTIVES: The impact of several environmental and genetic factors on diabetes is well documented. Though the association between the vitamin D receptor (VDR) gene polymorphisms and type 2 diabetes mellitus (T2DM) has been analyzed in different ethnic groups, the results have been inconsistent. The aim of this study was to evaluate the possible association between VDR FokI polymorphism and genetic susceptibility to T2DM in Tunisian population. METHODS: A total of 439 unrelated patients with T2DM and 302 healthy controls were included in the study...
July 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/27834324/assay-for-identification-of-heterozygous-single-nucleotide-polymorphism-ala67thr-in-human-poliovirus-receptor-gene
#18
Shyam Sundar Nandi, Deepa Kailash Sharma, Jagadish M Deshpande
BACKGROUND & OBJECTIVES: It is important to understand the role of cell surface receptors in susceptibility to infectious diseases. CD155 a member of the immunoglobulin super family, serves as the poliovirus receptor (PVR). Heterozygous (Ala67Thr) polymorphism in CD155 has been suggested as a risk factor for paralytic outcome of poliovirus infection. The present study pertains to the development of a screening test to detect the single nucleotide (SNP) polymorphism in the CD155 gene. METHODS: New primers were designed for PCR, sequencing and SNP analysis of Exon2 of CD155 gene...
July 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/27834323/association-of-ctg-repeat-polymorphism-in-carnosine-dipeptidase-1-cndp1-gene-with-diabetic-nephropathy-in-north-indians
#19
Ashok K Yadav, Nisha Sinha, Vinod Kumar, Anil Bhansali, Pinaki Dutta, Vivekanand Jha
BACKGROUND & OBJECTIVES: CNDP1 gene, present on chromosome 18q22.3-23, encodes carnosinase, the rate-limiting enzyme in hydrolysis of carnosine to ß-alanine and L-histidine. Linkage of CTG trinucleotide (leucine) repeat polymorphism in CNDP1 gene with diabetic nephropathy has been observed in several populations. However, this association is conflicting and population-dependent. We investigated this association in type 2 diabetes mellitus (T2DM) patients with and without nephropathy in north India...
July 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/27834322/a-structural-epidemiological-genetic-overview-of-klebsiella-pneumoniae-carbapenemases-kpcs
#20
REVIEW
C H Swathi, Rosy Chikala, K S Ratnakar, V Sritharan
Klebsiella pneumoniae carbapenemases (KPCs) are plasmid encoded carbapenem hydrolyzing enzymes which have the potential to spread widely through gene transfer. The instability of upstream region of blaKPC accelerates emergence of different isoforms. Routine antibiotic susceptibility testing failed to detect KPC producers and some commercial kits have been launched for early identification of KPC producers. Notable among the drugs under development against KPC are mostly derivatives of polymixin; ß-lactamase inhibitor NXL104 with combination of oxyimino cephalosporin as well as with ceftazidime; a novel tricyclic carbapenem, LK-157, potentially useful against class A and class C enzymes; BLI-489-a bicyclic penem derivative; PTK-0796, a tetracycline derivative and ACHN-490...
July 2016: Indian Journal of Medical Research
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