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Indian Journal of Medical Research

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https://www.readbyqxmd.com/read/29749370/fanconi-anaemia-presenting-as-tonsillar-squamous-cell-carcinoma
#1
Y S Sarma, M Sriharibabu
No abstract text is available yet for this article.
January 2018: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/29749369/extended-spectrum-%C3%AE-lactamase-carbapenemase-producing-gram-negative-bacilli-in-neonates-from-a-tertiary-care-centre-in-dibrugarh-assam-india
#2
LETTER
Utpala Devi, Reeta Bora, Jayanta Kumar Das, Jagadish Mahanta
No abstract text is available yet for this article.
January 2018: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/29749368/effect-of-inherited-red-cell-defects-on-growth-of-plasmodium-falciparum-an-in-vitro-study
#3
Vrushali Pathak, Roshan Colah, Kanjaksha Ghosh
Background & objectives: High prevalence of certain polymorphic alleles of erythrocytes in malaria endemic area has been linked to the resistance provided by these alleles against parasitic infestations. Numerous studies undertaken to demonstrate this correlation have generated conflicting results. This study was undertaken to investigate the abilities of various polymorphic erythrocytes to support in vitro growth of Plasmodium falciparum parasites. Methods: In this study under in vitro condition the ability of P...
January 2018: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/29749367/use-of-succinic-oxalic-acid-in-reducing-the-dosage-of-colistin-against-new-delhi-metallo-%C3%AE-lactamase-1-bacteria
#4
Ravichandiran Kumar, Brinda Chandar, Madasamy Parani
Background & objectives: New Delhi metallo-β-lactamase 1 (NDM-1) cleaves the beta-lactam ring, and confers bacterial resistance against most of the beta-lactam antibiotics, except tigecycline and colistin. Among these two antibiotics, colistin is considered toxic, and therefore, its clinical use and dosage need cautious approach. In the present study, six organic acids were screened individually and in combination of two acids for their effectiveness against NDM-1 Escherichia coli and a combination of colistin and oxalic or succinic acid was tested to find out the potential of combination therapy for reducing the dose of toxic colistin...
January 2018: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/29749366/experimental-zika-virus-infection-in-aedes-aegypti-susceptibility-transmission-co-infection-with-dengue-chikungunya-viruses
#5
Devendra T Mourya, Mangesh D Gokhale, Triparna D Majumdar, Pragya D Yadav, Vimal Kumar, Mangala S Mavale
Background & objectives: There are reports about the susceptibility of Aedes mosquitoes to ZIKV from various countries, however, no such information is available from Indian sub-continent, although, high level of group cross-reactivity of ZIKV with other flaviviruses has been reported. During outbreak situations, many cases of Dengue (DEN) and Chikungunya (CHIK) are reported. In such scenario, vector mosquitoes are likely to get co-infection/secondary-infection with one or other virus...
January 2018: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/29749365/antimicrobial-resistance-in-beta-haemolytic-streptococci-in-india-a-four-year-study
#6
Nidhi Bhardwaj, Purva Mathur, Bijayini Behera, Kushal Mathur, Arti Kapil, Mahesh C Misra
Background & objectives: The incidence and severity of invasive and non-invasive infections demonstrate variability over time. The emerging resistance of Group A streptococci (GAS) to commonly used antibiotics is of grave concern. This study was conducted to assess the antimicrobial resistance of beta-haemolytic streptococci (βHS) in India and to ascertain the molecular mechanisms of resistance. Methods: All isolates of βHS from the Trauma Centre of All India Institute of Medical Sciences (AIIMS) (north India), and heavily populated area of old Delhi from 2010 to 2014 and Yashoda Hospital, Secunderabad (in south India, 2010-2012) and preserved isolates of βHS at AIIMS (2005-2009) were included...
January 2018: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/29749364/cytopenia-in-adult-brucellosis-patients
#7
Safak Kaya, Nazif Elaldi, Ozcan Deveci, Ahmet Emre Eskazan, Muhammed Bekcibasi, Salih Hosoglu
Background & objectives: Brucellosis can lead to haematological abnormalities including cytopenia confusing with haematological malignancies. The aim of this study was to compare the main characteristics of brucellosis patients without cytopenia (Group 1) and with cytopenia (Group 2). Methods: This five-year period study which was performed in two referral hospitals in Turkey, included all adult brucellosis patients. Abnormally, low counts of leucocyte or haemoglobin or platelets in a patient were considered as cytopenia...
January 2018: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/29749363/a-non-inferiority-randomized-controlled-clinical-trial-comparing-unani-formulation-psoralen-plus-ultraviolet-a-sol-in-chronic-plaque-psoriasis
#8
Neena Khanna, Tamanna Nazli, Khalid Mahmud Siddiqui, Mani Kalaivani
Background & objectives: Though Unani medications have been used for centuries to treat psoriasis, there is paucity of published studies which have systematically evaluated their efficacy and safety. This study was conducted to establish non-inferiority of Unani medications (oral UNIM-401 and topical UNIM-403) vs psoralen plus ultraviolet A (PUVA) sol in treatment of moderate-severe chronic plaque psoriasis (CPP) in achieving psoriasis area severity index (PASI) 75 at 12 wk and to estimate proportion of patients who relapsed in follow up period of 12 weeks, after having achieved PASI 50...
January 2018: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/29749362/effects-of-synbiotics-on-ileal-microbiota
#9
Shunichiro Komatsu, Eiji Sakamoto, Takashi Asahara, Koji Nomoto, Masato Nagino
Background & objectives: Despite advancements in molecular-based methods, the composition of the human ileal microbiota and the effects of synbiotics/probiotics on its microbes remain poorly understood. The aim of this study was to determine the composition of the mucus microbiota in the human ileum and to assess the effects of oral administration of synbiotics on the microbiota. Methods: As part of a clinical trial for synbiotics treatment and surgical infection, ileal mucus was sampled when resection of the ileocecal portion was required...
January 2018: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/29749361/risk-factors-for-ruptured-intracranial-aneurysms
#10
Guang-Xian Wang, Dong Zhang, Zhi-Ping Wang, Liu-Qing Yang, Hua Yang, Wen Li
Background & objectives: The treatment of unruptured intracranial aneurysms (IAs) remains controversial; the ability to predict the risk of rupture for an aneurysm would be of clinical value. The aim of this study was to determine and evaluate the predictive value of the risk factors of IA rupture. Methods: This retrospective study involved 379 consecutive patients with 441 aneurysms between August 2011 and July 2014. Based on clinical data and computed tomography angiography findings, the potential of risk factors to predict the aneurysmal rupture was assessed using statistical methods...
January 2018: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/29749360/utility-of-cystatin-c-as-a-potential-bladder-tumour-biomarker-confirmed-by-surface-plasmon-resonance-technique
#11
Anna Tokarzewicz, Tomasz Guszcz, Anna Onopiuk, Robert Kozlowski, Ewa Gorodkiewicz
Background & objectives: The determination of cystatin C (cysC) may be helpful in diagnosis and monitoring of cancer because the pathogenesis of cancer is linked with an increased activity of cysteine peptidases (cathepsins) and a decrease of cysC concentration. This study was aimed to examine the utility of cysC as a marker of bladder cancer (BCa) to be used in the diagnosis. Methods: This study was conducted with 90 patients with BCa and 27 healthy people...
January 2018: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/29749359/immunohistochemistry-on-pattern-of-ocular-adnexal-tumours-in-a-tertiary-eye-care-centre-of-northeast-india
#12
Dipankar Das, Harsha Bhattacharjee, Apurba Deka, Panna Deka, Samir Serasiya, Kasturi Bhattacharjee, Jayanta Kumar Das, Ganesh Chandra Kuri, Eknath Pawar, Rushil Kumar Saxena
Background & objectives: Ocular and adnexal tumours are important causes of morbidity in India and globally. Immunohistochemistry (IHC) is a vital molecular pathology tool, which helps to diagnose a tumour with more accuracy. The present study was undertaken to document the profile of ocular and adnexal tumour with IHC at a tertiary eye care center in Northeast India. Methods: This was a prospective and laboratory-based study. Histopathological and IHC study of the ocular and adnexal tumour was carried out from 2012 to 2014...
January 2018: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/29749358/field-evaluation-of-the-biolarvicide-spinosad-20-per-cent-emulsifiable-concentrate-in-comparison-to-its-12-per-cent-suspension-concentrate-formulation-against-culex-quinquefasciatus-the-vector-of-bancroftian-filariasis-in-india
#13
Candasamy Sadanandane, Kasinathan Gunasekaran, Ponnusamy Sivagnana Boopathi Doss, Purushothaman Jambulingam
Background & objectives: Biolarvicides may offer alternatives to chemical larvicides as these are known to be safe to environment and selective against the target species. However, only a limited number of biolarvicides have been approved for mosquito larval control. In the current study, a new formulation of spinosad, 20 per cent emulsifiable concentrate (EC) was tested for its efficacy against Culex quinquefasciatus, in comparison to its 12 per cent suspension concentrate (SC). Methods: Spinosad 20 per cent EC was tested against Cx...
January 2018: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/29749357/-mycoplasma-pneumoniae-a-significant-but-underrated-pathogen-in-paediatric-community-acquired-lower-respiratory-tract-infections
#14
REVIEW
Surinder Kumar
Lower respiratory tract infections are considered a common cause responsible for morbidity and mortality among children, and Mycoplasma pneumoniae is identified to be responsible for up to 40 per cent of community-acquired pneumonia in children greater than five years of age. Extrapulmonary manifestations have been reported either due to spread of infection or autoimmune mechanisms. Infection by M. pneumoniae has high incidence and clinical importance but is still an underrated disease. Most widely used serologic methods are enzyme immunoassays for detection of immunoglobulin M (IgM), IgG and IgA antibodies to M...
January 2018: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/29749356/advances-challenges-in-leptospiral-vaccine-development
#15
REVIEW
Garba Bashiru, Abdul Rani Bahaman
Considerable progress has been made in the field of leptospiral vaccines development since its first use as a killed vaccine in guinea pigs. Despite the fact that the immunity conferred is restricted to serovars with closely related lipopolysaccharide antigen, certain vaccines have remained useful, especially in endemic regions, for the protection of high-risk individuals. Other conventional vaccines such as the live-attenuated vaccine and lipopolysaccharide (LPS) vaccine have not gained popularity due to the reactive response that follows their administration and the lack of understanding of the pathogenesis of leptospirosis...
January 2018: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/29749355/collaborating-centres-rediscovering-an-extended-arm-of-world-health-organization
#16
Poonam Khetrapal Singh
No abstract text is available yet for this article.
January 2018: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/29749354/lymphatic-filariasis-elimination-programme-in-assam-india-needs-change-in-mass-drug-administration-strategy-to-target-the-focus-of-infection
#17
Abdul Mabood Khan
No abstract text is available yet for this article.
January 2018: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/29749353/spinosad-a-biorational-mosquito-larvicide-for-vector-control
#18
Kamaraju Raghavendra, Poonam Sharma Velamuri
No abstract text is available yet for this article.
January 2018: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/29749352/world-leprosy-day-2018-how-forward-respecting-the-past
#19
EDITORIAL
Bernard Naafs
No abstract text is available yet for this article.
January 2018: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/29664044/tuberculosis-of-the-shoulder-caries-sicca
#20
Vipul Vijay, Raju Vaishya
No abstract text is available yet for this article.
December 2017: Indian Journal of Medical Research
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