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Indian Journal of Medical Research

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https://www.readbyqxmd.com/read/28256477/oro-facial-digital-syndrome-type-ii-with-lingual-lipomas
#1
Riaz Abdulla, Maya Somasundaran
No abstract text is available yet for this article.
October 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/28256476/difference-in-vector-ticks-dropping-rhythm-governs-the-epidemiology-of-crimean-congo-haemorrhagic-fever-kyasanur-forest-disease-in-india
#2
LETTER
Devendra T Mourya, Gajanan N Sapkal, Pragya D Yadav
No abstract text is available yet for this article.
October 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/28256475/extracorporeal-membrane-oxygenation-ecmo-as-a-rescue-treatment-in-acute-respiratory-distress-syndrome-caused-by-ah1n1-virus-infection
#3
LETTER
Marzena Zielinska, Alicja Bartkowska-Sniatkowska, Magdalena Checinska, Jowita Rosada-Kurasinska, Waldemar Golebiowski
No abstract text is available yet for this article.
October 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/28256474/long-term-outbreak-of-klebsiella-pneumoniae-third-generation-cephalosporin-use-in-a-neonatal-intensive-care-unit-in-north-india
#4
Tuhina Banerjee, Amitabha Bhattacharjee, Supriya Upadhyay, Shweta Mishra, Karuna Tiwari, Shampa Anupurba, Malay Ranjan Sen, Sriparna Basu, Ashok Kumar
BACKGROUND & OBJECTIVES: The indiscriminate use of third generation cephalosporin has contributed to the emergence and widespread dissemination of extended spectrum β lactamases (ESBL) genes in Klebsiella pneumoniae. This study was undertaken to elaborate the genetic behaviour of ESBL - producing K. pneumoniae isolates in the neonatal intensive care unit (NICU) of a tertiary care hospital in north India causing successive outbreaks in context with empirical third generation cephalosporin use...
October 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/28256473/antidepressant-anxiolytic-activities-of-n-pyridin-3-yl-quinoxalin-2-carboxamide-a-novel-serotonin-type-3-receptor-antagonist-in-behavioural-animal-models
#5
Dilip Kumar Pandey, Thangraj Devadoss, Neha Modak, Radhakrishnan Mahesh
BACKGROUND & OBJECTIVES: Alteration in the serotonin leads to the psychological illness, such as depression, anxiety, schizophrenia, eating disorders, obsessive-compulsive disorder, panic disorders and migraines. The objective of the current study was to investigate the antidepressant and anxiolytic activities of N-(pyridin-3-yl) quinoxalin-2-carboxamide (QCF-21), a novel 5-HT3receptor antagonist in preclinical models of depression and anxiety. METHODS: Antidepressant activity was evaluated in preliminary tests such as forced swim and tail suspension tests (FST & TST)...
October 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/28256472/a-cost-effective-anaerobic-culture-method-its-comparison-with-a-standard-method
#6
Uma Shankar Saha, Richa Misra, Dinesh Tiwari, Kashi Nath Prasad
Twenty six anaerobes were recovered from 150 deep-seated abscess samples cultured by the proposed two-step combustion-modified candle-jar system and Anoxomat. The degree of growth and colony size were similar in both systems, except for Clostridium difficile. The modified candle-jar system was found to be a sensitive and cost-effective alternative that might be used in resource-limited settings.
October 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/28256471/risk-factors-associated-with-fluoroquinolone-resistant-enterococcal-urinary-tract-infections-in-a-tertiary-care-university-hospital-in-north-india
#7
Tuhina Banerjee, Shampa Anupurba
BACKGROUND & OBJECTIVES: Fluoroquinolone resistance in both Gram-positive and Gram-negative bacteria has increased with the widespread use of fluoroquinolones. Fluoroquinolone resistance in Gram-negative bacilli has been widely studied, though staphylococci and enterococci are also notably resistant. Enterococci being the second most common cause of healthcare-associated urinary tract infections (UTIs) fluoroquinolones are often the drug of choice. This study was undertaken to assess the risk factors associated with fluoroquinolone-resistant enterococcal UTI in a tertiary level health facility in north India...
October 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/28256470/molecular-characterization-of-orientia-tsutsugamushi-serotypes-causing-scrub-typhus-outbreak-in-southern-region-of-andhra-pradesh-india
#8
K Usha, E Kumar, Usha Kalawat, B Siddhartha Kumar, A Chaudhury, D V R Sai Gopal
BACKGROUND & OBJECTIVES: Scrub typhus is a vector-borne zoonotic infection caused by Orientiatsutsugamushi. Local epidemiology of the circulating serotypes of scrub typhus is not available from most parts of India. We conducted this study for the diagnosis of scrub typhus using IgM ELISA and to detect O. tsutsugamushi serotypes circulating in southern Andhra Pradesh, India. METHODS: Samples were collected from patients clinically suspected to have scrub typhus and were subjected to IgM ELISA to measure IgM antibodies against O...
October 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/28256469/epidemiological-investigation-of-an-outbreak-of-typhoid-fever-in-jorhat-town-of-assam-india
#9
Jashbeer Singh Roy, Lahari Saikia, Mithu Medhi, Dipak Tassa
BACKGROUND & OBJECTIVES: Typhoid fever is a global health problem and is also endemic in India. An outbreak of fever occurred in January 2014 in Jorhat Town in Assam, India. Here we report the results of an investigation done to find out the aetiology and source of the outbreak. METHODS: The affected areas were visited on January 23, 2014 by a team of Jorhat district Integrated Disease Surveillance Project personnel. A total of 13 blood samples from patients with fever as first symptom and six water samples were collected from the affected areas...
October 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/28256468/computational-prediction-of-immunodominant-antigenic-regions-potential-protective-epitopes-for-dengue-vaccination
#10
Karthikeyan Muthusamy, Krishnasamy Gopinath, Dharmalingam Nandhini
BACKGROUND & OBJECTIVES: Epitope-based vaccines (EVs) are specific, safe and easy to produce. However, vaccine failure has been frequently reported due to variation within epitopic regions. Therefore, development of vaccines based on conserved epitopes may prevent such vaccine failure. This study was undertaken to identify highly conserved antigenic regions in the four dengue serotypes to produce an epitope-based dengue vaccine. METHODS: Polyprotein sequences of all four dengue serotypes were collected and aligned using MAFFT multiple sequence alignment plugin with Geneious Pro v6...
October 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/28256467/antibacterial-nanosilver-coated-orthodontic-bands-with-potential-implications-in-dentistry
#11
Rahul Damodaran Prabha, Rajasigamani Kandasamy, U Sajeev Sivaraman, Maya A Nandkumar, Prabha D Nair
BACKGROUND & OBJECTIVES: Fixed orthodontic treatment, an indispensable procedure in orthodontics, necessitates insertion of dental bands. Insertion of band material could also introduce a site of plaque retention. It was hypothesized that band materials with slow-release antimicrobial properties could help in sustained infection control, prevention of dental plaque formation and further associated health risks. Considering the known antimicrobial proprieties of silver, a coating of silver nanoparticle (SNP) onto the stainless steel bands was done and characterized for its beneficial properties in the prevention of plaque accumulation...
October 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/28256466/evaluation-of-the-effects-of-omega-3-interferon-alpha-2b-administration-on-partial-bladder-outlet-obstruction-in-a-rat-model
#12
Fatih Firat, Nihat Uluocak, Fikret Erdemir, Dogan Atilgan, Fatma Markoc, Bekir Suha Parlaktas, Adem Yasar
BACKGROUND & OBJECTIVES: In bladder outlet obstruction-induced rat models, the transforming growth factor-beta (TGF-β) and collagen ratios have been shown to be increased. Increased TGF-β leads to fibrosis. In this study, the effect of omega-3 and interferon alpha-2b (IFN α-2b) was investigated on oxidative stress, inflammation and fibrosis in bladder structure in a partial bladder outlet obstruction (PBOO) rat model. METHODS: A total of 35 male Wistar albino rats, weighing 300-350 g, were used in the study...
October 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/28256465/comparison-of-haemoglobin-estimates-using-direct-indirect-cyanmethaemoglobin-methods
#13
Priyanka Gupta Bansal, Gurudayal Singh Toteja, Neena Bhatia, Sanjeev Gupta, Manpreet Kaur, Tulsi Adhikari, Ashok Kumar Garg
BACKGROUND & OBJECTIVES: Estimation of haemoglobin is the most widely used method to assess anaemia. Although direct cyanmethaemoglobin method is the recommended method for estimation of haemoglobin, but it may not be feasible under field conditions. Hence, the present study was undertaken to compare indirect cyanmethaemoglobin method against the conventional direct method for haemoglobin estimation. METHODS: Haemoglobin levels were estimated for 888 adolescent girls aged 11-18 yr residing in an urban slum in Delhi by both direct and indirect cyanmethaemoglobin methods, and the results were compared...
October 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/28256464/prevention-of-phosphine-induced-cytotoxicity-by-nutrients-in-hepg2-cells
#14
Marzieh Rashedinia, Akram Jamshidzadeh, Abbas Rezaiean Mehrabadi, Hossein Niknahad
BACKGROUND & OBJECTIVES: Phosphides used as an insecticide and rodenticide, produce phosphine (PH3) which causes accidental and intentional poisoning cases and deaths. There is no specific treatment or antidote available for PH3poisoning. It is suggested that PH3-induced toxicity is associated with adenosine triphosphate (ATP) depletion; therefore, in this study the effect of some nutrients was evaluated on PH3cytotoxicity in a cell culture model. METHODS: PH3was generated from reaction of zinc phosphide (10 mM) with water in the closed culture medium of HepG2 cells, and cytotoxicity was measured after one and three hours of incubation...
October 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/28256463/characterization-of-cardiac-arrest-in-the-emergency-department-of-a-brazilian-university-reference-hospital-a-prospective-study
#15
Cassia Regina Vancini-Campanharo, Rodrigo Luiz Vancini, Claudio Andre Barbosa de Lira, Marília Dos Santos Andrade, Maria Carolina Barbosa Teixeira Lopes, Meiry Fernanda Pinto Okuno, Ruth Ester Assayag Batista, Álvaro Nagib Atallah, Aécio Flávio Teixeira de Góis
BACKGROUND & OBJECTIVES: Sudden cardiac arrest (CA) represents one of the greatest challenges for medicine due to the vast number of cases and its social and economic impact. Despite advances in cardiopulmonary resuscitation (CPR) techniques, mortality rates have not significantly decreased over decades. This study was undertaken to characterize patients that have suffered CA and to identify factors related to mortality. METHODS: This prospective study was conducted at Emergency Department of São Paulo Hospital, Brazil...
October 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/28256462/morphological-spectrum-of-mediastinal-lesions-with-special-emphasis-on-evaluation-of-needle-biopsy-an-experience-from-a-tertiary-care-hospital
#16
Riti Aggarwal, Seema Rao, Prem Chopra, Sunita Bhalla, C L Vijay, Belal Bin Asaf, Arvind Kumar
BACKGROUND & OBJECTIVES: Mediastinal lesions are uncommon and are infrequently encountered in routine clinical practice. Hence, there is a need for more elaborate studies of mediastinal lesions to make the pathologists and clinicians aware of the large spectrum of these lesions. The present study describes the histomorphological spectrum of various mediastinal lesions in a tertiary care hospital in India, along with the discussion of some unusual and interesting cases. Considering the limited diagnostic material obtained in guided biopsies, the adequacy of such tissue for providing a definite opinion was also evaluated...
October 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/28256461/observation-on-frequency-clinico-pathological-significance-of-various-cytogenetic-risk-groups-in-multiple-myeloma-an-experience-from-india
#17
Pratibha S Kadam Amare, Hemani Jain, Shraddha Nikalje, Manju Sengar, Hari Menon, Nitin Inamdar, P G Subramanian, Sumeet Gujral, Tanuja Shet, Sridhar Epari, Reena Nair
BACKGROUND & OBJECTIVES: Multiple myeloma (MM) is a plasma cell malignancy characterized by cytogenetic heterogeneity. In comparison with conventional karyotyping, fluorescence in situ hybridization (FISH) can efficiently detect various genetic changes in non-cycling plasma cells in 50-90 per cent of MM cases. The present study was undertaken in MM patients to evaluate the frequency and clinico-pathological significance of various cytogenetic abnormalities in the Indian population. METHODS: Interphase FISH was applied on purified plasma cells of 475 patients with MM using specific probes...
October 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/28256460/international-open-trial-of-uniform-multidrug-therapy-regimen-for-leprosy-patients-findings-implications-for-national-leprosy-programmes
#18
Ponnaiah Manickam, Sanjay M Mehendale, Bathyala Nagaraju, Kiran Katoch, Abdul Jamesh, Ramalingam Kutaiyan, Shen Jianping, Shivakumar Mugudalabetta, Vitthal Jadhav, Prabu Rajkumar, Jayasree Padma, Kanagasabai Kaliaperumal, Vijayakumar Pannikar, Padabettu Krishnamurthy, Mohan D Gupte
BACKGROUND & OBJECTIVES: Uniform therapy for all leprosy patients will simplify leprosy treatment. In this context, we evaluated six-month multidrug therapy (MDT) currently recommended for multibacillary (MB) patients as uniform MDT (U-MDT) in a single-arm open trial under programme conditions. Primary objective was to determine efficacy to prevent five-year cumulative five per cent relapse. Secondary objectives were to assess acceptability, safety and compliance. METHODS: Newly detected, treatment-naive leprosy patients were enrolled in India (six sites) and P...
October 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/28256459/apoptosis-autophagy-endoplasmic-reticulum-stress-in-diabetes-mellitus
#19
REVIEW
Levent Demirtas, Aydin Guclu, Fatih Mehmet Erdur, Emin Murat Akbas, Adalet Ozcicek, Didem Onk, Kultigin Turkmen
The prevalence of diabetes mellitus (DM) is increasing secondary to increased consumption of food and decreased physical activity worldwide. Hyperglycaemia, insulin resistance and hypertrophy of pancreatic beta cells occur in the early phase of diabetes. However, with the progression of diabetes, dysfunction and loss of beta cells occur in both types 1 and 2 DM. Programmed cell death also named apoptosis is found to be associated with diabetes, and apoptosis of beta cells might be the main mechanism of relative insulin deficiency in DM...
October 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/28256458/fats-fatty-acids-in-indian-diets-time-for-serious-introspection
#20
REVIEW
Indu Mani, Anura V Kurpad
Recommended dietary allowances for fat and fatty acid (FA) intakes are set on global standards aimed at prevention of lifestyle diseases. Yet, the fat composition of a diet is both ethnic/region specific as well as income dependent. Indian diets are predominantly vegetarian and relatively low in fat. Furthermore, the main sources of fat are of plant origin rather than animal origin. This results in a diet that is relatively low in saturated FA, high in n-6 polyunsaturated fatty acids (PUFA), and very low in n-3 PUFA...
October 2016: Indian Journal of Medical Research
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