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Indian Journal of Medical Research

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https://www.readbyqxmd.com/read/29998880/an-older-male-with-fever-induced-brugada-syndrome
#1
Xiang-Fei Feng, Kai Guo
No abstract text is available yet for this article.
April 2018: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/29998879/identification-of-a-case-of-srd5a3-congenital-disorder-of-glycosylation-cdg1q-by-exome-sequencing
#2
LETTER
Neerja Gupta, Gaurav Verma, Madhulika Kabra, Sunita Bijarnia-Mahay, Aparna Ganapathy
No abstract text is available yet for this article.
April 2018: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/29998878/ader-ades-mutations-overexpression-of-the-adeabc-efflux-system-in-ciprofloxacin-resistant-acinetobacter-baumannii-clinical-isolates
#3
Abdolaziz Rastegar Lari, Abdollah Ardebili, Ali Hashemi
Background & objectives: : Overexpression of efflux pumps is a cause of acquired resistance to fluoroquinolones in Acinetobacter baumannii. The present study was done to investigate the presence and overexpression of AdeABC efflux system and to analyze the sequences of AdeR-AdeS regulatory system in ciprofloxacin-resistant A. baumannii isolates. Methods: : Susceptibility of 50 clinical A. baumannii isolates to ciprofloxacin, imipenem, ceftazidime, cefepime and gentamicin antimicrobials was evaluated by agar dilution method...
April 2018: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/29998877/pharmacokinetics-of-colistin-in-patients-with-multidrug-resistant-gram-negative-infections-a-pilot-study
#4
Vikas Gautam, Nusrat Shafiq, Johan W Mouton, Sameer Malhotra, Satinder Kaur, Pallab Ray
Background & objectives: There is little information concerning intravenously (i.v.) administered colistin in patients with multidrug-resistant (MDR) Gram-negative infections. Thus, this pilot prospective study was undertaken to characterize efficacy and pharmacokinetics of colistin in patients with MDR Gram-negative infections. Methods: Nine patients with age >12 yr and MDR Gram-negative infections were included, of whom six were given colistin at the doses of 2 MU, while three patients were given 1 MU i...
April 2018: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/29998876/association-of-furanone-c-30-with-biofilm-formation-antibiotic-resistance-in-pseudomonas-aeruginosa
#5
Jingming Zhao, Wei Cheng, Xigang He, Yanli Liu, Ji Li, Jiaxing Sun, Jinfeng Li, Fangfang Wang, Yufang Gao
Background & objectives: Pseudomonas aeruginosa is an opportunistic pathogen that can cause nosocomial bloodstream infections in humans. This study was aimed to explore the association of furanone C-30 with biofilm formation, quorum sensing (QS) system and antibiotic resistance in P. aeruginosa. Methods: An in vitro model of P. aeruginosa bacterial biofilm was established using the standard P. aeruginosa strain (PAO-1). After treatment with 2.5 and 5 μg/ml of furanone C-30, the change of biofilm morphology of PAO-1 was observed, and the expression levels of QS-regulated virulence genes (lasB, rhlA and phzA2), QS receptor genes (lasR, rhlR and pqsR) as well as QS signal molecule synthase genes (lasI, rhlI, pqsE and pqsH) were determined...
April 2018: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/29998875/detection-of-parvovirus-b19-in-selected-high-risk-patient-groups-their-phylogenetic-selection-analysis
#6
Kumaran Vadivel, Ramamurthy Mageshbabu, Sathish Sankar, Amita Jain, Vivekanandan Perumal, Padma Srikanth, Ghosh Asit Ranjan, Aravindan Nair, Eric A F Simoes, Balaji Nandagopal, Gopalan Sridharan
Background & objectives: Human parvovirus B19V (B19V) is known to be associated with erythema infectiosum commonly in children, aplastic crisis, especially in persons with underlying haemolytic disorders, hydrops fetalis in pregnancies and arthritis. This cross-sectional study was aimed to determine the presence of B19V infection in childhood febrile illnesses, association of B19V with arthropathies and in adult patients with end-stage renal disease (ESRD) on dialysis. The genetic diversity among the sequences was also analysed...
April 2018: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/29998874/plasma-urinary-catecholamines-urinary-vanillylmandelic-acid-levels-in-patients-with-generalized-vitiligo
#7
Binamra Basnet, Aditya Bhushan, Rehan Khan, Guresh Kumar, Vinod Kumar Sharma, Alpana Sharma, Somesh Gupta
Background & objectives: Vitiligo is an acquired skin disease characterized by depigmented areas of the skin. Increased release of catecholamines from autonomic nerve endings in microenvironment of melanocytes in affected skin might be involved in the aetiopathogenesis of vitiligo. Levels of catecholamines are considered as being related to onset or worsening of the disease. Therefore, in this study, the role of catecholamines was evaluated in mapping disease stability and outcome of vitiligo patients undergoing melanocyte transfer...
April 2018: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/29998873/lymphopenia-induced-proliferation-of-cd4-t-cells-is-associated-with-cd4-t-lymphocyte-exhaustion-in-treated-hiv-infected-patients
#8
Evgeniya V Saidakova, Konstantin V Shmagel, Larisa B Korolevskaya, Nadezhda G Shmage, Valeriy A Chereshnev
Background & objectives: Under the lymphopenic condition, T-cells divide to maintain their peripheral pool size. Profound chronic lymphopenia in some treated HIV-infected patients, characterized by poor T-cell recovery, might result in intensive homeostatic proliferation and can cause T-cell exhaustion and/or senescence. The present study was undertaken to evaluate the homeostatic proliferation of CD4+ T-cells in treated HIV-infected individuals, and to determine the amount of phenotypically exhausted and senescent CD4 T-lymphocytes...
April 2018: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/29998872/development-of-a-screening-instrument-for-autism-spectrum-disorder-chandigarh-autism-screening-instrument
#9
Priti Arun, Bir Singh Chavan
Background & objectives: There is a paucity of trained professionals for the diagnosis of autism spectrum disorder (ASD), and a large number of cases go undetected and are diagnosed only during adolescence. There is no screening instrument specifically developed for screening of Indian population for ASD. This study was undertaken to develop a screening instrument to screen ASD in north Indian Hindi speaking population by multipurpose health workers. Methods: A 37-item instrument in Hindi with dichotomous yes/no responses [Chandigarh Autism Screening Instrument (CASI)] was developed to be applied on children aged 1...
April 2018: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/29998871/expression-analysis-of-apolipoproteins-ai-aiv-in-hepatocellular-carcinoma-a-protein-based-hepatocellular-carcinoma-associated-study
#10
Dipu Bharali, Basu Dev Banerjee, Mausumi Bharadwaj, Syed Akhtar Husain, Premashis Kar
Background & objectives: Hepatocellular carcinoma (HCC) is one of the leading causes of cancer mortality. The objective of this study was to find out the differential expression of apolipoproteins (ApoAI and ApoAIV) in HCC and cases of liver cirrhosis and chronic hepatitis (controls) without HCC and to compare ApoAI and ApoAIV expression with alpha-foetoprotein (AFP), the conventional marker in HCC. Methods: Fifty patients with HCC and 50 controls comprising patients with liver cirrhosis (n=25) and chronic hepatitis (n=25) without HCC were included in this study...
April 2018: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/29998870/erythrocyte-membrane-fatty-acid-profile-serum-cytokine-levels-in-patients-with-non-alcoholic-fatty-liver-disease
#11
Bahareh Amirkalali, Masoud Reza Sohrabi, Ali Esrafily, Mahmoud Jalali, Ali Gholami, Payam Hosseinzadeh, Hossein Keyvani, Farzad Shidfar, Farhad Zamani
Background & objectives: Fatty acids may affect the expression of genes, and this process is influenced by sex hormones. Cytokines are involved in the pathogenesis of non-alcoholic fatty liver disease (NAFLD), so this study was aimed to assess the association of erythrocyte membrane fatty acids with three cytokines and markers of hepatic injury in NAFLD patients and to explore whether these associations were the same in both sexes. Methods: In this cross-sectional study, 62 consecutive patients (32 men and 30 women) with NAFLD during the study period...
April 2018: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/29998869/oxidative-stress-as-a-possible-pathogenic-cofactor-of-post-menopausal-osteoporosis-existing-evidence-in-support-of-the-axis-oestrogen-deficiency-redox-imbalance-bone-loss
#12
REVIEW
Gloria Bonaccorsi, Isabella Piva, Pantaleo Greco, Carlo Cervellati
Post-menopausal osteoporosis (PO) is one of the major health issues associated with menopause-related oestrogen withdrawal. Despite the intense research and the relevant progress achieved in the last two decades, the pathogenic mechanism underlying PO is still poorly understood. As a consequence of this gap in the knowledge, such disorder and the related complications are still difficult to be effectively prevented. A wealth of experimental and epidemiological/clinical evidence suggests that the endocrine change associated to menopausal transition might lead to a derangement of redox homeostasis, that is, the prelude to the health-threaten condition of oxidative stress (OxS)...
April 2018: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/29998868/chronic-obstructive-pulmonary-disease-in-non-smokers-is-it-a-different-phenotype
#13
Surinder K Jindal
No abstract text is available yet for this article.
April 2018: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/29998867/analyzing-lipids-in-the-liver-in-the-red-blood-cell-membrane-in-liver-diseases
#14
COMMENT
C E Eapen, Banumathi Ramakrishna, K A Balasubramanian
No abstract text is available yet for this article.
April 2018: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/29998866/world-immunization-week-2018-what-lessons-for-india
#15
EDITORIAL
T Jacob John
No abstract text is available yet for this article.
April 2018: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/29998865/universal-health-coverage-in-india-progress-achieved-the-way-forward
#16
EDITORIAL
Sanjay Zodpey, Habib Hasan Farooqui
No abstract text is available yet for this article.
April 2018: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/29923526/dermatitis-neglecta
#17
Sonali Langar, Sidharth Sonthalia
No abstract text is available yet for this article.
March 2018: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/29923525/an-unusual-cause-of-dysphagia-in-a-child-gastrointestinal-manifestations-of-epidermolysis-bullosa
#18
Raghu Prakash, Archana Puri
No abstract text is available yet for this article.
March 2018: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/29923524/circulation-of-nipah-virus-in-pteropus-giganteus-bats-in-northeast-region-of-india-2015
#19
LETTER
Pragya Yadav, Anakkathil Sudeep, Mangesh Gokhale, Shailesh Pawar, Anita Shete, Deepak Patil, Vimal Kumar, Rajen Lakra, Prasad Sarkale, Stuart Nichol, Devendra Mourya
No abstract text is available yet for this article.
March 2018: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/29923523/a-possible-need-for-routine-screening-for-strongyloides-stercoralis-infection-in-indian-haemophilia-patients
#20
LETTER
Rucha K Patil, Kanjaksha K Ghosh, S Chandrakala, Shrimati Shetty
No abstract text is available yet for this article.
March 2018: Indian Journal of Medical Research
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