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Indian Heart Journal

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https://www.readbyqxmd.com/read/28038723/the-value-of-wrist-circumference-for-predicting-the-presence-of-coronary-artery-disease-and-metabolic-syndrome
#1
Shokoufeh Hajsadeghi, Ata Firouzi, Pouria Bahadoran, Morteza Hassanzadeh
BACKGROUND: Recently, the value of various structural body components have been proposed for predicting cardio-metabolic risk. The present study aimed to assess the wrist circumference (WrC) as an alternative measure for differentiating patients with CAD and METs from those without CAD and METs. METHODS: We studied 228 consecutive subjects who underwent coronary angiography. Those with and without evidence of coronary artery involvement at angiography were considered as the coronary artery disease (CAD) group (n=139) and the non-CAD group (n=89), respectively...
December 2016: Indian Heart Journal
https://www.readbyqxmd.com/read/28038722/management-standards-for-stable-coronary-artery-disease-in-india
#2
Sundeep Mishra, Saumitra Ray, Jamshed J Dalal, J P S Sawhney, S Ramakrishnan, Tiny Nair, S S Iyengar, V K Bahl
Coronary artery disease (CAD) is one of the important causes of cardiovascular morbidity and mortality globally, giving rise to more than 7 million deaths annually. An increasing burden of CAD in India is a major cause of concern with angina being the leading manifestation. Stable coronary artery disease (SCAD) is characterised by episodes of transient central chest pain (angina pectoris), often triggered by exercise, emotion or other forms of stress, generally triggered by a reversible mismatch between myocardial oxygen demand and supply resulting in myocardial ischemia or hypoxia...
December 2016: Indian Heart Journal
https://www.readbyqxmd.com/read/28038721/assessment-of-inferior-vena-cava-diameter-by-echocardiography-in-normal-indian-population-a-prospective-observational-study
#3
Shivanand Patil, Santosh Jadhav, Natraj Shetty, Jayashree Kharge, Beeresha Puttegowda, Rangraj Ramalingam, Manjunath Nanjappa Cholenahally
BACKGROUND: The assessment of the IVC diameter is self explanatory for evaluation of the individuals' volume status. Studies regarding IVC diameter estimation in normal individuals are scarce. AIM: The present study aimed to define normal criteria of size and dynamics of the inferior vena cava (IVC) by M-mode echocardiography in normal individuals. METHODS: This was a prospective, single-center, observational study carried out at Sri Jayadeva Institute of Cardiovascular Sciences and Research between December 2011 and April 2014...
December 2016: Indian Heart Journal
https://www.readbyqxmd.com/read/28038720/prevalence-and-characterization-of-coronary-artery-disease-in-patients-with-symptomatic-bradyarrhythmias-requiring-pacemaker-implantation
#4
Mohammad S Alai, Jahangir Rashid Beig, Sanjay Kumar, Irfan Yaqoob, Imran Hafeez, Ajaz A Lone, Mohammad Iqbal Dar, Hilal A Rather
BACKGROUND: This study was conducted to assess the prevalence and characterization of CAD in high risk patients requiring pacemaker implantation for symptomatic bradyarrhythmias. METHODS: This study included 100 patients with symptomatic sinus node dysfunction or atrioventricular block, who were at high risk of CAD or had previously documented atherosclerotic vascular disease (ASCVD). Coronary angiography was performed before pacemaker implantation. CAD was defined as the presence of any degree of narrowing in at least one major coronary artery or its first order branch...
December 2016: Indian Heart Journal
https://www.readbyqxmd.com/read/28038719/testosterone-as-a-marker-of-coronary-artery-disease-severity-in-middle-aged-males
#5
Kunal Gururani, John Jose, Paul V George
Historically, higher levels of serum testosterone were presumed deleterious to the cardiovascular system. In the last two decades, studies have suggested that low testosterone levels are associated with increased prevalence of risk factors for cardiovascular disease (CVD), including dyslipidemia and diabetes. This is a cross sectional study. The aim of our study was to determine the relationship between serum testosterone levels and angiographic severity of coronary artery disease (CAD). Serum testosterone levels were also correlated with flow mediated dilation of brachial artery (BAFMD) - an indicator of endothelial function...
December 2016: Indian Heart Journal
https://www.readbyqxmd.com/read/28038718/preoperative-values-of-inflammatory-markers-predict-clinical-outcomes-in-patients-after-cabg-regardless-of-the-use-of-cardiopulmonary-bypass
#6
Dariusz Plicner, Jarosław Stoliński, Marcin Wąsowicz, Bugusław Gawęda, Hubert Hymczak, Bogusław Kapelak, Rafał Drwiła, Anetta Undas
OBJECTIVE: The impact of systemic inflammation on clinical outcomes after CABG surgery is still controversial. In this study, we evaluated the impact of the markers of inflammation, endothelial damage and platelet activation on clinical outcomes after on- and off-pump CABG. METHODS: A group of 191 consecutive on- and off-pump CABG patients were prospectively studied. Blood samples were drawn before surgery, 18-36h after the procedure and 5-7 days postoperatively and analyzed for 8-iso-prostaglandin F2α (8-iso-PGF2α), asymmetric dimethylarginine (ADMA) and β-thromboglobulin (β-TG)...
December 2016: Indian Heart Journal
https://www.readbyqxmd.com/read/28038717/american-college-of-cardiology-acc-s-pinnacle-india-quality-improvement-program-piqip-inception-progress-and-future-direction-a-report-from-the-piqip-investigators
#7
Ankur Kalra, Nathan Glusenkamp, Karen Anderson, Ram N Kalra, Prafulla G Kerkar, Ganesh Kumar, Thomas M Maddox, William J Oetgen, Salim S Virani
Cardiovascular diseases have surpassed infectious disorders to become the leading cause of morbidity and mortality in India.(1) A national-level registry comprehensively documenting the current-day prevalence of cardiovascular risk factors and disease burden among patients seeking care in the outpatient setting in India is currently non-existent. With a burgeoning urban population, the cardiovascular disease burden in India is set to skyrocket, with an estimated 18 million productive years of life lost by 2030...
December 2016: Indian Heart Journal
https://www.readbyqxmd.com/read/27931562/management-protocols-of-stable-coronary-artery-disease-in-india-executive-summary
#8
Sundeep Mishra, Saumitra Ray, Jamshed J Dalal, J P S Sawhney, S Ramakrishnan, Tiny Nair, S S Iyengar, Vinay K Bahl
No abstract text is available yet for this article.
November 2016: Indian Heart Journal
https://www.readbyqxmd.com/read/27931561/good-news-for-kerala
#9
LETTER
Prabha Nini Gupta, Ullas R Mullamalla, Alummoottil George Koshy, Sivaprasad Kunjukrishanpillai, Radhakrishanan Vellikat Velayudhan
No abstract text is available yet for this article.
November 2016: Indian Heart Journal
https://www.readbyqxmd.com/read/27931560/a-kerala-model-for-cardiovascular-research
#10
REVIEW
Geevar Zachariah, Mohanan Padinharepurayil, Krishnan Mangalath Narayanan
India's contribution to cardiovascular research has been dismal with a share of only 1% of total number of papers published in the world during the period 1999-2008. Based on two recent studies published from Kerala, the Kerala ACS Registry and the CSI Kerala CRP Study and four other studies being undertaken in Kerala, we think that a Kerala model for cardiovascular research can be conceptualized. This model which consists of funding by professional organization of cardiologists with wide participation of cardiologists, physicians, health workers, nurses, and in some situations general public, logistics looked after by a central coordinator and study design by panel of experts or institutions of repute in the region and carried out at low cost can be considered for implementation in rest of India...
November 2016: Indian Heart Journal
https://www.readbyqxmd.com/read/27931559/role-of-cardiac-renin-angiotensin-system-in-ischemia-reperfusion-injury-and-preconditioning-of-heart
#11
REVIEW
Vimal Agrawal, Jeetendra Kumar Gupta, Shaiba Sana Qureshi, Vishal Kumar Vishwakarma
Cardio-vascular diseases are the leading cause of morbidity and mortality. Ischemia is a state of oxygen deprivation in tissues, whereas reperfusion is restoration of blood flow in ischemic tissues. Myocardial damage of tissue during reperfusion after ischemic insult is known as myocardial ischemia-reperfusion (I/R) injury. It induces damage to cardiac muscle via increasing expression of oxygen, sodium and calcium ions which are responsible in the activation of proteases and cell death. Heart renin angiotensin system (RAS) plays an important role in the myocardial ischemia and reperfusion injury...
November 2016: Indian Heart Journal
https://www.readbyqxmd.com/read/27931558/time-to-shift-from-contemporary-to-high-sensitivity-cardiac-troponin-in-diagnosis-of-acute-coronary-syndromes
#12
REVIEW
Jamshed J Dalal, C K Ponde, Brian Pinto, C N Srinivas, Joy Thomas, Sunil Kumar Modi, Sanjay Mehta, Suvin Shetty, Manimarane, Bhupen Desai
Early rule-in and rule-out of non-ST-segment elevation myocardial infarction (NSTEMI) is a challenge. In patients with inconclusive findings on ECG, cardiac biomarkers play a crucial role in the diagnosis. The introduction of the new high-sensitive cardiac troponin test (hs-TnI assay) has changed the landscape of NSTEMI diagnosis. The new hs-TnI assay can detect troponin values at a lower level compared with a contemporary cardiac troponin (cTn) assay. The hs-cTnI assay has a coefficient of variation of ≤10%, well below the 99th percentile value...
November 2016: Indian Heart Journal
https://www.readbyqxmd.com/read/27931557/dedicated-bifurcation-stents-mechanistic-hardware-and-technical-aspects
#13
Sundeep Mishra
Percutaneous coronary intervention (PCI) in bifurcation lesions is associated with lower success rate, higher acute complication rates and higher event rates in follow-up. The reason for this higher than usual complication rate relates to the relationship between anatomy, flow, and atheroma distribution in bifurcation lesions. Further, stenting these lesions can be a prolonged procedure and can be technically more demanding. The most common complication is the loss of significant side branch (SB). Main vessel (MV) stenting may enhance the carina displacement and atheroma shift across the SB ostium leading to SB ostium narrowing...
November 2016: Indian Heart Journal
https://www.readbyqxmd.com/read/27931556/non-physician-health-workers-for-improving-adherence-to-medications-and-healthy-lifestyle-following-acute-coronary-syndrome-24-month-follow-up-study
#14
Krishna Kumar Sharma, Rajeev Gupta, Mukul Mathur, Vishnu Natani, Sailesh Lodha, Sanjeeb Roy, Denis Xavier
OBJECTIVE: To evaluate usefulness of non-physician health workers (NPHW) to improve adherence to medications and lifestyles following acute coronary syndrome (ACS). METHODS: We randomized 100 patients at hospital discharge following ACS to NPHW intervention (n=50) or standard care (n=50) in an open label study. NPHW was trained for interventions to improve adherence to medicines - antiplatelets, β-blockers, renin-angiotensin system (RAS) blockers and statins and healthy lifestyles...
November 2016: Indian Heart Journal
https://www.readbyqxmd.com/read/27931555/risk-factor-profile-of-calcific-aortic-stenosis
#15
I Sathyamurthy, Shaji Alex, K Kirubakaran, G Sengottuvelu, K N Srinivasan
BACKGROUND: Calcific aortic stenosis and coronary artery disease share common risk factors. In some of the previous studies statins have been used to retard the progression of aortic stenosis, but the results were inconsistent. METHODS: One hundred and ten patients of CAS above the age of 40 years have undergone clinical, biochemical and echocardiographic evaluation. Coronary angiograms were done in 66% of them. RESULTS: Male to female ratio was 2:1...
November 2016: Indian Heart Journal
https://www.readbyqxmd.com/read/27931554/a-study-to-derive-distribution-of-carotid-intima-media-thickness-and-to-determine-its-correlation-with-cardiovascular-risk-factors-in-asymptomatic-nationwide-indian-population-score-india
#16
Ravi R Kasliwal, Manish Bansal, Nagaraj Desai, Bhavesh Kotak, Ammar Raza, Hardik Vasnawala, Amit Kumar
BACKGROUND: There is presently no data to describe normal distribution of carotid intima-media thickness (CIMT), an established measure of subclinical atherosclerosis, in Indian subjects. METHODS: In this multi-centric study, 1229 subjects with age ≥30 years and no previous cardiovascular disease (CVD) underwent CVD risk factor assessment and CIMT measurement. Mean far wall common carotid artery IMT was measured on both sides and averaged. RESULTS: Mean age of the subjects was 48...
November 2016: Indian Heart Journal
https://www.readbyqxmd.com/read/27931553/change-in-left-ventricular-systolic-function-in-patients-with-st-elevation-myocardial-infarction-evidence-for-smoker-s-paradox-or-pseudo-paradox
#17
Burak Acar, Ozcan Ozeke, Sefa Unal, Mustafa Karakurt, Meryem Kara, Ozgur Kirbas, Fatih Sen, Ahmet Korkmaz, Dursun Aras, Sinan Aydogdu
BACKGROUND: The 'smoker's paradox' refers to the observation of favorable prognosis in current smokers following an acute ST elevation myocardial infarction (STEMI) in the era of fibrinolysis, however, several STEMI studies have demonstrated conflicting results in patients undergoing primary percutaneous coronary intervention (p-PCI). OBJECTIVE: Aim of the current study was to evaluate the impact of cigarette smoking on left ventricular function in STEMI patients undergoing p-PCI...
November 2016: Indian Heart Journal
https://www.readbyqxmd.com/read/27931552/effects-of-sustained-release-trimetazidine-on-chronically-dysfunctional-myocardium-of-ischemic-dilated-cardiomyopathy-six-months-follow-up-result
#18
A Momen, M Ali, P K Karmakar, M Z Ali, A Haque, M R Khan, M I Khalil, M S Hossain, R M Huda, M N Goni
BACKGROUND: Ischemic cardiomyopathy is a growing burden in third world countries. So far, benefits of trimetazidine in this group of patients have been suggested by clinical trials mainly conducted in Europe. We evaluated the effect of trimetazidine on ischemic dilated cardiomyopathy in our population. METHODS AND RESULTS: 98 patients (aged 58.5±9.2 years), admitted with decompensated heart failure with previous history of MI and/or documentation of significant CAD with previous CAG, were chosen for the study...
November 2016: Indian Heart Journal
https://www.readbyqxmd.com/read/27931551/metabolic-manipulation-in-dilated-cardiomyopathy-assessing-the-role-of-trimetazidine
#19
Suman Jatain, Aditya Kapoor, Archana Sinha, Roopali Khanna, Sudeep Kumar, Naveen Garg, Satyendra Tewari, Pravin Goel
OBJECTIVES: To study the role of metabolic modulator (trimetazidine: TMZ) in dilated cardiomyopathy (DCM). Optimizing altered substrate metabolism in heart failure (HF) with metabolic modulators allows more efficacious energy production from glucose than from free fatty acids. METHODS: 100 patients of DCM (47.7 years, NYHA class 2.17, LVEF 27.3%) were randomized to TMZ (20mg tid, n=50) vs conventional therapy (n=50). Functional status, BNP and various echocardiographic parameters were assessed at 3-6 months...
November 2016: Indian Heart Journal
https://www.readbyqxmd.com/read/27931550/off-pump-coronary-artery-bypass-grafting-using-continuous-heparin-infusion
#20
Kamales Kumar Saha, Dinesh Kumar Sangwan, Pravin K Shroff, Mandar Manohar Deval, Kakalee K Saha, Rinu V Jacob, Ratnaprobha Adsul, Lukash Jagdale
OBJECTIVES: Levels of anticoagulation during off-pump coronary artery bypass grafting (OPCAB) remain controversial. Prolonged activated clotting time (ACT) during OPCAB increases blood loss during surgery and can also cause paradoxical increase in postoperative myocardial infarction. Shorter ACT can increase thrombotic complication. Maintaining a steady ACT level is challenging. We have used continuous heparin infusion after initial bolus during OPCAB to maintain a steady low target ACT...
November 2016: Indian Heart Journal
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