Gerty Schreibelt, Tjitske Duiveman-de Boer, Jeanette M Pots, Tom G M van Oorschot, Annemiek J de Boer, Nicole M Scharenborg, Mandy W M M van de Rakt, Kevin Bos, Anna L de Goede, Katja Petry, Mareke Brüning, Caroline Angerer, Carola Schöggl, Andreas Dzionek, I Jolanda M de Vries
Dendritic cell (DC) vaccination is a promising approach to induce tumor-specific immune responses in cancer patients. Until recently, most DC vaccines were based on in vitro-differentiated monocyte-derived DCs. However, through development of efficient isolation techniques, the use of primary blood dendritic cell subsets has come within reach. Manufacturing of blood-derived DCs has multiple advances over monocytes-derived DCs, including more standardized isolation and culture protocols and shorter production processes...
2024: Methods in Cell Biology