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Ethiopian Medical Journal

Nebiyu Negussu, Birhan Mengistu, Biruck Kebede, Kebede Deribe, Ephrem Ejigu, Gemechu Tadesse, Kalkidan Mekete, Mesfin Sileshi
Schistosomiasis and soil-transmitted helminthes are among seventeen WHO prioritized neglected tropical diseases that infect humans. These parasitic infections can be treated using single-dose and safe drugs. Ethiopia successfully mapped the distribution of these infections nationwide. According to the mapping there are an estimated 37.3 million people living in schistosomiasis endemic areas, and 79 million in schistosomiasis and soil-transmitted helminthes endemic areas. The Federal Ministry of Health successfully scaled up Schistosomiasis and schistosomiasis and soil-transmitted helminthes intervention in endemic areas and treated over 19 million individuals in 2015...
2017: Ethiopian Medical Journal
Kebede Deribe, Biruck Kebede, Belete Mengistu, Henok Negussie, Mesfin Sileshi, Mossie Tamiru, Sara Tomczyk, Fasil Tekola-Ayele, Gail Davey, Amha Fentaye
Podoconiosis is a geochemical disease occurring in individuals exposed to red clay soil of volcanic origin. This Neglected Tropical Disease (NTD) is highly prevalent in Ethiopia. According to the nationwide mapping in 2013, the disease is endemic in 345 districts, where an estimated 35 million people live. The government of Ethiopia prioritized podoconiosis as one of eight priority NTDs and included it in the national integrated master plan for NTDs. An integrated lymphoedema management guideline has been developed...
2017: Ethiopian Medical Journal
Kadu Meribo, Biruck Kebede, Sindew Mekasha Feleke, Birhan Mengistu, Abate Mulugeta, Mesfin Sileshi, Abdi Samuel, Kebede Deribe, Zerihun Tadesse
Onchocerciasis is a severe parasitic infection which causes disabling skin and subcutaneous tissue changes. The disease is endemic in many African countries including Ethiopia. In 2013, Ethiopia launched Onchocerciasis elimination program with the goal of attaining interruption of onchocerciasis transmission nationwide by 2020. The country has successfully scaled up interventions and achieved 100% geographic coverage in all known endemic districts. The main strategy for interrupting the disease is mass drug administration (MDA) delivered two times per year...
2017: Ethiopian Medical Journal
Belete Mengistu, Kebede Deribe, Fikreab Kebede, Sarah Martindale, Mohammed Hassan, Heven Sime, Charles Mackenzie, Abate Mulugeta, Mossie Tamiru, Mesfin Sileshi, Asrat Hailu, Teshome Gebre, Amha Fentaye, Biruck Kebede
Lymphatic filariasis (LF) is one of the most debilitating and disfiguring diseases common in Ethiopia and is caused by Wuchereria bancrofti. Mapping for LF has shown that 70 woredas (districts) are endemic and 5.9 million people are estimated to be at risk. The national government's LF elimination programme commenced in 2009 in 5 districts integrated with the onchocerciasis programme. The programme developed gradually and has shown significant progress over the past 6 years, reaching 100% geographical coverage for mass drug administration (MDA) by 2016...
2017: Ethiopian Medical Journal
Habtamu Bedimo Beyene, Abyot Bekele, Amanu Shifara, Yehenew A Ebstie, Zelalem Desalegn, Zeyede Kebede, Abate Mulugeta, Kebede Deribe, Zerihun Tadesse, Tamrat Abebe, Biruck Kebede, Getaneh Abrha, Daddi Jima
Dracunculiasis, also named Guinea Worm Disease (GWD), is one of the Neglected Tropical Diseases (NTDs) caused by a parasitic nematode known as Dracunculus medinensis and has been known since antiquity as 'fiery serpent' from Israelites. It is transmitted to humans via drinking contaminated water containing infective copepods. Given, its feasibility for eradication, the Guinea Worm Eradication Program (GWEP) was launched in 1980 with the aim of eradicating the disease. Since its inception, GWEP has made an extraordinary progress in interrupting transmission...
2017: Ethiopian Medical Journal
A Deribew, B Kebede, G A Tessema, Y A Adama, A Misganaw, T Gebre, A Hailu, S Biadgilign, A Amberbir, B Desalegn, A A Abajobir, O Shafi, S F Abera, N Negussu, B Mengistu, A T Amare, A Mulugeta, Z Kebede, B Mengistu, Z Tadesse, M Sileshi, M Tamiru, E A Chromwel, S D Glenn, J D Stanaway, K Deribe
INTRODUCTION: Neglected tropical diseases (NTDs) are important public health problems in Ethiopia. In 2013, the Federal Ministry of Health (FMOH) has launched a national NTD master plan to eliminate major NTDs of public health importance by 2020. Benchmarking the current status of NTDs in the country is important to monitor and evaluate the progress in the implementation of interventions and their impacts. Therefore, this study aims to assess the trends of mortality and Disability-adjusted Life-Years (DALY) for the priority NTDs over the last 25 years...
2017: Ethiopian Medical Journal
Sebastien Gagneux
Tuberculosis (TB) is a growing public health threat, particularly in the face of the global epidemics of multidrug resistance. Given the limited efficacy of the current TB vaccine and the recent clinical failure of the most advanced new TB vaccine candidate, novel concepts for vaccine design should be explored. Most T cell antigens in the human-adapted Mycobacterium tuberculosis complex (MTBC) are evolutionarily conserved and under strong purifying selection, indicating that host immune responses targeting these antigens might not be protective...
April 2016: Ethiopian Medical Journal
Samuel Sisay Hailu, Eyoel Degafu Amerga, Yocabel Gorfu, Daniel Zewedneh
Kartagener's syndrome is a rare autosomal recessive genetic disorder that causes a defect in the action of the cilia lining the respiratory tract. Patients usually present with chronic recurrent rhinosinusitis, otitis media, pneumonia, and bronchiectasis caused by Pseudomonas infection. In this case report, we present a 12-year old female with Kartagener's syndrome from Tikur Anbessa Teaching Hospital which to our knowledge is the first of it's kind to be reported in Ethiopia. The clinical and imaging findings are discussed...
April 2016: Ethiopian Medical Journal
Daniel Zemenfes, Zelalem Semegnew
Colonic lipoma is a rare non-epithelial mesenchymal tumour which is the second most common benign tumour of the colon excluding hyper-plastic polyps. It is often small and asymptomatic but may become symptomatic and mimic malignant lesions as the size increases. This is a case report of a 68 year-old female patient who presented with lower abdominal pain, constipation and rectal bleeding of one year duration. Colonoscopy revealed a sessile tumour 40 cm from the anal verge with an inconclusive histology. After incising and removing the lipoma, the redundant mucosal fold was then resected...
April 2016: Ethiopian Medical Journal
Desalew Mekonnen, Tadesse Mitiku, Yenesew Tamir, Aklilu Azazh
Snakebite is an important public health challenge. Venomous snake bites cause significant morbidity and mortality if treatment measures, especially antivenom therapy, are delayed. We did a case series of 27 adult patients admitted after snakebite to the medical wards of Gondar University Hospital (GUH) from September 2013 to August 2014. The age range was from 15 to 74 years. The male to female ratio was 8:1. The majority (25) of patients presented after 12 hours of being bitten. Most of the bites occurred on the legs...
April 2016: Ethiopian Medical Journal
Hailu Abera, Mihret Woldemichael
INTRODUCTION: Diabetes mellitus is becoming a common chronic disease in both developed and developing nations and is associated with significant cardiovascular disease morbidity and mortality. The presence of hypertension in patients with diabetes mellitus doubles the risk of cardiovascular disease including coronary heart disease, congestive heart failure, ischemic and hemorrhagic stroke, renalfailure and peripheral arterial disease. OBJECTIVE: The aim of this study was to assess the pattern of antihypertensive drug therapy among diabetic hypertensive patients in Zewditu Memorial Hospital Diabetic Clinic in Addis Ababa...
April 2016: Ethiopian Medical Journal
Alhaji Aliyu, Tukur Dahiru, Reginald O Obiako, Lawal Amadu, Lawal B Biliaminu, Ephraim I Akase
BACKGROUND: Tetanus, a disease that is largely preventable, is still a major public health problem in the developing world and is associated with high morbidity and mortality. There is a paucity of published literature on adult (non-neonatal) tetanus in this study area in Nigeria. METHODS: This was a study describing the clinical characteristics of patients who were clinically diagnosed with tetanus in Ahmadu Bello University Teaching Hospital (ABUTH) Zaria, northwest of Nigeria between January 2001 and December 2014...
April 2016: Ethiopian Medical Journal
Fasika Amdeslasie, Mizan Kidanu, Wondwosen Lerebo, Dagim Ali
BACKGROUND: Injuries are a neglected health problem in developing countries. Ethiopia has a high incidence of road traffic accidents and trauma constitutes about half of surgical emergencies among patient seen at health facilities. The objective of this study was to determine the pattern of trauma among patient seen at emergency outpatient departments of public hospitals in northern Ethiopia METHODS: Retrospective data on patient seen at the hospitals during a one-year period (January 1, 2013-December 31, 2013) was collected...
April 2016: Ethiopian Medical Journal
Zelalem Assefa
BACKGROUND: Appendiceal mass is one of the complications of acute appendicitis. The management of patients with appendiceal mass is controversial and different treatment options have been suggested. OBJECTIVE: The objective of this study was to assess the results of conservative management of patients with appendiceal mass followed by interval appendicecomy. METHODS: The study was a retrospective analysis of 73 medical records of patients with appendiceal mass who were managed conservatively between March 2007 and February 2014...
April 2016: Ethiopian Medical Journal
Senbeta Guteta, Dejuma Yadeta, Aklilu Azazh, Dufera Mekonnen
BACKGROUND: Valvular heart disease has been a significant cause of heart disease worldwide. In Ethiopia, it particularly affects young individuals and constitutes the major cause of cardiovascular disease. Factors associated with choice of treatment for advanced valvular heart disease are variable. The objective of this study is to review surgery done for Ethiopian patients with valvular heart disease. METHODS: We analyzed data on patients who had valve surgery and follow-up at the Tikur Anbessa Specialized Hospital cardiology unit...
April 2016: Ethiopian Medical Journal
Meaza Demissie
No abstract text is available yet for this article.
April 2016: Ethiopian Medical Journal
Abebe Bekele, Addisu Firew
Hydatid cyst of the breast is extremely rare even in endemic areas and it only accounts for 0.27% of all hydatid cyst disease cases. It can either be a primary site or part of a disseminated hydatidosis. Surgery remains to be a treatment of choice. Only few reports are published in the literatures and most of the reported cases have been diagnosed postoperatively as it is not easy to reach at a definitive diagnosis with clinical examination and radiological investigations only. This is a case of an isolated hydatid cyst of breast in an 18-year old woman from the Amhara region, Ethiopia...
January 2016: Ethiopian Medical Journal
Adugna Abera, Geremew Tasew, Abay Degu, Mulusew Almneh, Abate Mulugeta, Abraham Aseffa, Endalamaw Gadisa
Visceral leishmaniasis (VL) is a ftial and growing public health problem in Ethiopia. VL is recently reported outside the major endemic foci, the lowlands in the northwest and the Omo and Abaroba-plain, Segen and Woito valleys in the southwest. Here, we report a visceral leishmaniasis case from Benishangul-Gumuz Regional state near the Guba area. The patient had no history of travel to known VL endemic areas. The patient is a temporary farm laborer from West Go'jam Zone, Wanbermna District in Amhara Regional State...
January 2016: Ethiopian Medical Journal
Eskedar Awelachew Eshete, Tewabech Zewde Weldemariam
BACKGROUND: Physiological range of clinically important hematological laboratory values and lipid profiles of healthy population in Ethiopia is not well assessed. OBJECTIVE: to determine hematologic and lipid profiles of healthy blood donors in Addis Ababa. METHODS: Red Cross Society located in Addis Ababa was selected as a study area. 336 donors; age range between 18-58 years participated. Venous blood sample was collected by tube containing Ehtylenediaminetetraaceticacid tri potassium (EDTA) for hematology test and sterile tube for lipid test...
January 2016: Ethiopian Medical Journal
Girmay Hagos, Reiye Esayas, Kibrom G/Selassie
OBJECTIVE: Chronic empyema is a serious problem and is often difficult to manage. Its incidence has dropped worldwide, but continues to pose health problems in low and middle income countries. This study has been conducted to assess the outcome of open thoracic window in patients with neglected chronic thoracic empyemain Ethiopian patients. METHODS: A six-year (June 2008 to October 2014) retrospective study was conducted on thirty five patients (ten females and twenty five males, age ranging from 30-70 years)...
January 2016: Ethiopian Medical Journal
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