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British Journal of Radiology

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https://www.readbyqxmd.com/read/28782377/what-is-the-impact-of-innovation-on-output-in-healthcare-with-a-special-focus-on-treatment-innovations-in-radiotherapy-a-literature-review
#1
Maria Jacobs, Liesbeth Boersma, Andre Dekker, Rachelle Swart, Philippe Lambin, Dirk De Ruysscher, Frank Verhaegen, Joost Stultiens, Bram Ramaekers, van Merode Frits
OBJECTIVES: To analyse how often innovations in healthcare are evaluated regarding output, especially in radiotherapy. Output was defined as either survival, toxicity, safety, service, efficiency or costeffectiveness. METHODS: A systematic literature review was conducted, using three search strategies: 1) innovations in general healthcare; 2) radiotherapy-specific innovations, i.e. organisational innovations and general implementation of innovations; 3) innovations per tumour group/radiotherapy technique...
August 6, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28766950/imaging-features-of-rare-mesenychmal-liver-tumors-beyond-hemangiomas
#2
Rajesh Thampy, Khaled M Elsayes, Christine O Menias, Perry J Pickhardt, Hyunseon C Kang, Sandeep Deshmukh, Kareem Ahmed, Brinda Rao Korivi
Tumors arising from mesenchymal tissue components such as vascular, fibrous and adipose tissue can manifest in the liver. Although histopathology is often necessary for definitive diagnosis, many of these lesions exhibit characteristic imaging features. The radiologist plays an important role in suggesting the diagnosis, which can direct appropriate immunohistochemical staining at histology. The aim of this review is to present clinical and imaging findings of a spectrum of mesenchymal liver tumors such as hemangioma, epithelioid hemangioendothelioma, lipoma, PEComa, angiosarcoma, inflammatory myofibroblastic tumor, solitary fibrous tumor, leiomyoma, leiomyosarcoma, Kaposi sarcoma, mesenchymal hamartoma, undifferentiated embryonal sarcoma, rhabdomyosarcoma and hepatic metastases...
August 2, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28749712/lung-cancer-screening-low-dose-ct-for-lung-cancer-screening-recent-trial-results-and-next-steps
#3
Emma L O'Dowd, David R Baldwin
Screening for lung cancer using low-dose computed tomography has already been implemented in North America following the results of the National Lung Screening Trial. Outside North America, clinicians and researchers are addressing issues that may have a major impact on the success of screening programmes by reviewing results of existing trials and by designing new research and pilot programmes. This review summarises the work that has been done to try to answer the remaining questions and highlights potential barriers which may affect screening uptake and cost effectiveness...
July 27, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28749707/imaging-findings-of-alagille-syndrome-in-young-infants-differentiation-from-biliary-atresia
#4
Solbee Han, Tae Yeon Jeon, Sook Min Hwang, So-Young Yoo, Yon Ho Choe, Suk-Koo Lee, Ji Hye Kim
OBJECTIVES: To compare the imaging findings using ultrasonography, MR cholangiopancreatography (MRCP), and intraoperative cholangiography (IOC) between Alagille syndrome (AGS) and biliary atresia (BA) in young infants with cholestatic jaundice. METHODS: The institutional review board approved this retrospective study. Ultrasonography (n = 55), MRCP (n = 33), and IOC (n = 22) studies were performed in 55 infants (all younger than 3 months) with AGS (n = 7) and BA (n = 48)...
July 27, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28749231/phase-%C3%A2-study-of-concurrent-chemoradiotherapy-with-a-modified-target-volumes-delineation-method-for-inoperable-esophageal-cancer-patients
#5
Wenyi Zhang, Huifang Li, Xingxing Chen, Meng Su, Ruifang Lin, Changlin Zou
OBJECTIVE: A Phase || study was designed to test the safety and efficacy of concurrent chemoradiotherapy with a modified target volumes delineation method for inoperable esophageal cancer patients. METHODS: All eligible patients were treated with concurrent chemoradiotherapy. The method of delineating target volume was as follow: Planning gross target volume (PGTV) was defined as the primary gross tumor volume (GTV-t) plus a 3 cm margin longitudinally and a 0...
July 27, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28749202/abbreviated-breast-mri-for-screening-women-with-dense-breast-the-ea1141-trial
#6
Christiane K Kuhl
Early diagnosis improves survival of women with breast cancer. Mammographic screening improves early diagnosis of breast cancer. And yet, there appears to be room for improvement. Major shortcomings of mammographic screening are overdiagnosis of prognostically unimportant cancer, as well as underdiagnosis of cancers that are indeed relevant. Failure to detect biologically relevant breast cancer with mammographic screening is driven by host-related factors, i.e. breast tissue density, but also tumour-related factors: Biologically relevant cancers may exhibit imaging features that renders them indistinguishable from normal or benign breast tissue on mammography...
July 27, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28749176/quantifying-potential-reduction-in-contrast-dose-with-monoenergetic-images-synthesized-from-duallayer-detector-spectral-ct
#7
Derek S Tsang, Thomas E Merchant, Sophie E Merchant, Hanna Smith, Yoad Yagil, Chia-Ho Hua
OBJECTIVES: To estimate the potential dose reduction in iodinated contrast when interpreting monoenergetic images from spectral CT. METHODS: 51 pediatric patients received contrast-enhanced CT simulation for radiation therapy using a single-source, dual-layer detector spectral CT. The contrast-to-noise ratios (CNR) of blood vessels were measured relative to surrounding soft tissue. CNRs on monoenergetic 40-70 keV images were compared with polychromatic 120 kVp images...
July 27, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28749175/direct-shoulder-magnetic-resonance-arthrography-for-superior-labral-anterior-to-posterior-slap-and-bankart-lesions-investigation-into-the-appropriate-dose-and-level-of-local-anesthesia
#8
Sun Hwa Lee, Seong Jong Yun, Hyeon Hwan Jo, Dong Hyeon Kim, Jae Gwang Song, Yong Sung Park
OBJECTIVES: To compare contrast leakage, pain score, image quality, and diagnostic performance at different doses and levels of local anesthesia for direct shoulder magnetic resonance arthrography (MRA). METHODS: Patients (n=157) were prospectively enrolled and allocated to group 1 (no local anesthetic), group 2 (local anesthesia to subcutaneous fat level; lidocaine 1-2 mL), group 3 (to deltoid muscle level; 3-5 mL), or group 4 (to subscapularis muscle level; 6-8 mL)...
July 27, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28749174/microbeam-radiation-therapy-grid-therapy-and-beyond-a-clinical-perspective
#9
Elisabeth Schültke, Jacques Balosso, Thomas Breslin, Guido Cavaletti, Valentin Djonov, Francois Esteve, Michael Grotzer, Guido Hildebrandt, Alexander Valdman, Jean A Laissue
Microbeam irradiation is spatially fractionated radiation on a micrometer scale. Microbeam irradiation with therapeutic intent has become known as microbeam radiation therapy (MRT). The basic concept of MRT was developed in the 1980s, but it has not yet been tested in any human clinical trial, even although there is now a large number of animal studies demonstrating its marked therapeutic potential with an exceptional normal tissue sparing effect. Furthermore, MRT is conceptually similar to macroscopic grid based radiation therapy which has been used in clinical practice for decades...
July 27, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28749173/assessment-of-sacroiliitis-for-the-diagnosis-of-spondyloarthropathy-fat-saturated-t2-weighted-imaging-with-stir-versus-fat-saturated-contrast-enhanced-t1-weighted-imaging
#10
Siyoun Sung, Hyun Su Kim, Jong Won Kwon
OBJECTIVES: To evaluate whether there is significant differences between contrastenhanced fat-saturated T1-weighted imaging and non-enhanced fat-suppression imaging for diagnosing sacroiliitis in patients with inflammatory back pain. METHODS: Ninety-two patients, consisting of 46 men and 46 women (mean age: 34 years; range: 15-63 years), who met at least four out of five Assessment in SpondyloArthritis international Society (ASAS) criteria for inflammatory low back pain were enrolled in this study...
July 27, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28749172/no-differences-in-radiological-changes-after-3d-conformal-vs-vmat-based-stereotactic-radiotherapy-for-early-stage-non-small-cell-lung-cancer
#11
Serena Badellino, Jacopo Di Muzio, Giulia Schivazappa, Alessia Guarneri, Riccardo Ragona, Sara Bartoncini, Elisabetta Trino, Andrea Riccardo Filippi, Paolo Fonio, Umberto Ricardi
OBJECTIVES: To compare patterns of acute and late radiological lung injury following either 3D or image-guided VMAT stereotactic radiotherapy for stage I Non-Small-Cell Lung Cancer (NSCLC). METHODS: We included 148 patients from a prospective mono-institutional SBRT series (time interval 2004-2014), treated with prescription BED10 Gy (at 80%) in the range 100-120 Gy. The first 95 patients (2004-2010) were planned with 3D-CRT, with a stereotactic body frame. The second cohort (2010-2014) included 53 patients, planned with volumetric IMRT on a smaller PTV generated from a patient's specific ITV, with a frameless approach through cone-beam CT guidance...
July 27, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28749171/prospective-evaluation-of-a-specific-technique-of-sexual-function-preservation-in-external-beam-radiotherapy-for-prostate-cancer
#12
Hamza Samlali, Corina Udrescu, Ariane Lapierre, Ciprian Enachescu, Alain Ruffion, Patrice Jalade, Olivier Chapet
OBJECTIVES: Sexual preservation is an important issue in the treatment of localized prostate cancer. A technique of irradiation was developed to better preserve this function and has been evaluated. METHODS: Eleven patients, with no erectile dysfunction (ED), were treated with daily IMRTIGRT (total dose: 76-78 Gy). The pudendal arteries, penile bulb and cavernous body were delineated on the planning CT scan. The doses to these structures (with a 5 mm margin) were optimized to be as low as possible...
July 27, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28749170/multidetector-computedtomography-in-detection-of-troublesome-posterior-sectoral-hepatic-duct-communicating-with-cystic-duct
#13
Tatsuaki Sumiyoshi, Yasuo Shima, Takehiro Okabayashi, Yasuhiro Hata, Yoshihiro Noda, Michihiko Kouno, Kenta Sui, Yuji Negoro, Taijiro Sueda
OBJECTIVE: To investigate whether multiple detector computed tomography (MDCT) could detect troublesome aberrant posterior sectoral hepatic duct (PHD) communicating with cystic duct (CD). METHODS: The most troublesome bile duct anomaly during cholecystectomy is an aberrant PHD communicating with CD. It has been suggested that an unenhanced small duct between Rouviere's sulcus and CD on MDCT could be coincident to an aberrant PHD communicating with CD. A total of 224 patients who underwent laparotomy with complete lymph node dissection in the hepatoduodenal ligament for hepatobiliary or pancreatic tumor were enrolled...
July 27, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28749168/anxiety-reduction-and-emotional-self-care-using-the-u-technique-in-radiology%C3%A2-departments
#14
Alberto Martinez Lorca, Roberto Aguado, Manuela Martinez Lorca, Maria Carmen Zabala Baños
Daily clinical practice is an important source of stress and emotional exhaustion. In health field, patients could experience a significant number of emotional reactions. There are high levels of anxiety in patients referred for medical imaging, and these levels are even higher in patients undergoing complicated diagnostic procedures. All this shows the need to understand that anxiety must be diagnosed and treated. This situation forces radiologist to develop emotional and social skills to resolve difficulties that may arise in the communicative act...
July 27, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28749167/diagnostic-value-of-semiquantitative-and-quantitative-analysis-of-functional-parameters-in-multiparametric-mri-of-the-prostate
#15
Elke Hauth, Daniela Halbritter, Horst Jaeger, Horst Hohmuth, Meinrad Beer
OBJECTIVES: To determine the diagnostic value of semiquantitative and quantitative parameters of three functional techniques in multiparametric (mp)-MRI of the prostate. METHODS: Mp-MRI was performed in 110 patients with suspicion of prostate cancer (PCA) before TRUS-guided core biopsy. Peak-enhancement, initial and post-initial enhancement, iAUGC (initial area under gadolinium curve), Ktrans (forward rate constant), Kep (efflux rate constant), Ve (extracellular volume), ADC (apparent diffusion coefficient), and MR spectroscopy ratio were obtained for malignant and benign lesions...
July 27, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28749166/ablative-safety-margin-depicted-by-fusion-imaging-with-post-treatment-contrast-enhanced-ultrasound-and-pre-treatment-cect-cemri-after-radiofrequency-ablation-for-liver-cancers
#16
Xiao-Wan Bo, Hui-Xiong Xu, Le-Hang Guo, Li-Ping Sun, Xiao-Long Li, Chong-Ke Zhao, Ya-Ping He, Bo-Ji Liu, Dan-Dan Li, Kun Zhang, Dan Wang
OBJECTIVES: To evaluate the value of fusion imaging with post-treatment contrast-enhanced ultrasound (CEUS) and pre-treatment contrast-enhanced computed tomography/magnetic resonance imaging (CECT/CEMRI) in evaluating ablative safety margin after percutaneous ultrasound (US)-guided radiofrequency ablation (RFA) for liver cancers. METHODS: 34 consecutive patients with 47 liver lesions who had undergone RFA were included. Fusion imaging with post-treatment CEUS and pre-treatment CECT/CEMRI was carried out to evaluate local treatment response and ablative safety margin within 1-3 days after RFA...
July 27, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28749165/impact-of-robotic-ultrasound-image-guidance-on-plan-quality-in-sbrt-of-the-prostate
#17
Stefan Gerlach, Ivo Kuhlemann, Floris Ernst, Christoph Fürweger, Alexander Schlaefer
OBJECTIVES: Ultrasound provides good image quality, fast volumetric imaging, and is established for abdominal image guidance. Robotic transducer placement may facilitate intra-fractional motion compensation in radiation therapy. We consider integration with the CyberKnife and study whether the kinematic redundancy of a seven-degrees-of-freedom robot allows for acceptable plan quality for prostate treatments. METHODS: Reference treatment plans were generated for ten prostate cancer cases previously treated with the CyberKnife...
July 27, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28749164/distribution-and-chemical-forms-of-gadolinium-in-the-brain-a-review
#18
Tomonori Kanda, Yudai Nakai, Akifumi Hagiwara, Hiroshi Oba, Keiko Toyoda, Shigeru Furui
In the 3 years since residual gadolinium-based contrast agent (GBCA) in the brain was first reported, much has been learned about its accumulation, including the pathway of GBCA entry into the brain, the brain distribution of GBCA, and its excretion. Here we review recent progress in understanding the routes of gadolinium deposition in brain structures.
July 27, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28749163/development-of-a-paediatric-head-voxel-model-database-for-dosimetric-applications
#19
Andreas Stratis, Nathan Touyz, Guozhi Zhang, Reinhilde Jacobs, Ria Bogaerts, Hilde Bosmans
OBJECTIVES: To develop a database of paediatric head voxel models intended for Monte Carlo (MC) dosimetric applications. METHODS: Seventeen head and neck CT image datasets were retrieved from the Picture Archiving and Communicating System (PACS) of our hospital and were reformed into voxel models. Twenty two organs were segmented at each dataset. The segmented organ masses were compared to the respective age and gender specific ICRP reference mass value. Adjustments were made such that segmented and reference mass values coincide within a tolerance of 10%...
July 27, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28707543/pet-mri-knocking-on-the-doors-of-the-rich-and-famous
#20
Thomas Beyer, Marcus Hacker, Vicky Goh
Since 2010 the portfolio of positron emission tomography (PET)-based imaging has been expanded by industry with the introduction of combined whole-body PET/MRI systems with the intent of merging PET-based molecular imaging with the strengths of MRI. PET/MRI has created a lot of hype in the scientific community but comparatively little traction in the clinic. The first years of whole-body PET/MRI were used to address inherent technical challenges; however, it is now time to make use of the full potential of this integrated imaging modality...
July 27, 2017: British Journal of Radiology
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