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Arhiv za Higijenu Rada i Toksikologiju

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https://www.readbyqxmd.com/read/28033107/genotoxic-effects-of-the-carbamate-insecticide-pirimor-50%C3%A2-in-vicia-faba-root-tip-meristems-and-human-lymphocyte-culture-after-direct-application-and-treatment-with-its-metabolic-extracts
#1
Rafael Valencia-Quintana, Sandra Gómez-Arroyo, Juana Sánchez-Alarcón, Mirta Milić, José Luis Gómez Olivares, Stefan M Waliszewski, Josefina Cortés-Eslava, Rafael Villalobos-Pietrini, María Elena Calderón-Segura
The aim of the study was to evaluate genotoxic effects of Pirimor-50®, a pirimicarb-based formulation (50 % active ingredient), in human lymphocyte cultures and Vicia faba root meristems. Furthermore, the objective was to examine a combined influence of insecticide treatment with mammalian microsomal S9 and vegetal S10 metabolic fractions or S10 mix metabolic transformation extracts (after Vicia faba primary roots treatment with Pirimor-50®). We used sister chromatid exchange assay-SCE and measured cell cycle progression and proliferation (proportion of M1-M3 metaphases and replication index ratio-RI)...
December 1, 2016: Arhiv za Higijenu Rada i Toksikologiju
https://www.readbyqxmd.com/read/28033106/protective-effects-of-quercetin-and-vitamin-c-against-nicotine-induced-toxicity-in-the-blood-of-wistar-rats
#2
Milica G Paunović, Branka I Ognjanović, Miloš M Matić, Andraš Š Štajn, Zorica S Saičić
Nicotine is a potential inducer of oxidative stress, through which it can damage numerous biological molecules. The aim of our study was to investigate the prooxidative effects of nicotine and protective (additive or synergistic) effects of quercetin and vitamin C in the blood of experimental animals, to determine whether the combination of these antioxidants might be beneficial for clinical purposes. Wistar albino rats were receiving intraperitoneal nicotine injection (0.75 mg kg-1 per day) or saline (control group) or nicotine plus quercetin (40 mg kg-1 per day) and vitamin C (100 mg kg-1 per day) for three consecutive days...
December 1, 2016: Arhiv za Higijenu Rada i Toksikologiju
https://www.readbyqxmd.com/read/28033105/association-between-the-tp53-and-cyp2e1-5b-gene-polymorphisms-and-non-small-cell-lung-cancer
#3
Ahmet Oguz Ada, Serdar Bilgen, Volkan Karacaoglan, Celalettin Semih Kunak, Emre Soydas, Sibel Alpar, Meral Gulhan, Mumtaz Iscan
Non-small cell lung cancer (NSCLC) is the most common form of lung cancer. Genetic polymorphisms in tumour suppressor genes and genes encoding xenobiotic metabolising enzymes alter the activity of their corresponding enzymes and are important individual susceptibility factors for NSCLC. Because of the lack of information in literature, the aim of our study was to investigate the role of the tumour suppressor gene TP53 (Arg72Pro) and the xenobiotic metabolising CYP2E1*5B gene polymorphisms on the risk of NSCLC development...
December 1, 2016: Arhiv za Higijenu Rada i Toksikologiju
https://www.readbyqxmd.com/read/28033104/micronuclei-and-other-nuclear-anomalies-in-buccal-epithelial-cells-of-children-with-chronic-kidney-disease
#4
Banu Aykanat, Gonca Cakmak Demircigil, Necla Buyan, Esra Baskin, Kaan Gulleroglu, Kibriya Fidan, Umut Selda Bayrakci, Aydin Dalgic, Hamdi Karakayali, Mehmet Haberal, Sema Burgaz
The objective of this study was to reveal the likely genomic instability in children with chronic kidney disease (CKD) using micronucleus (MN) assay on buccal epithelial cells (BEC). We investigated the frequencies of micronuclei and other nuclear anomalies, such as nuclear buds, binucleated cells, condensed chromatin, and karyorrhectic and pyknotic cells in BEC. Children with CKD were grouped as follows: children in the pre-dialysis (PreD) stage (N=17), children on regular haemodialysis (HD) (N=14), and children who have undergone transplantation (Tx) (N=17)...
December 1, 2016: Arhiv za Higijenu Rada i Toksikologiju
https://www.readbyqxmd.com/read/28033103/the-sublethal-effects-of-2-4-dichlorophenoxy-acetic-acid-2-4-d-on-narrow-clawed-crayfish-astacus-leptodactylus-eschscholtz-1823
#5
A Çağlan Karasu Benli, Duygu Şahin, Rabia Sarıkaya, Burcu Koçak Memmi, Aylin Sepici Dinçel
2,4-D is a widely used phenoxy herbicide, potentially toxic to humans and biota. The objective of the present study was to reveal short term sublethal effects of 2,4-D on narrow-clawed freshwater crayfish (Astacus leptodactylus Eschscholtz, 1823), based on histology, total haemocyte counts, selected haemolymph parameters, and oxidative stress parameters. In the laboratory conditions crayfish specimens were exposed to 9 mg L-1 of 2,4-D for one week. Experiments were conducted under semi-static conditions in 20 L-capacity aquaria where 10 freshwater crayfish were stocked per aquarium...
December 1, 2016: Arhiv za Higijenu Rada i Toksikologiju
https://www.readbyqxmd.com/read/28033102/ectoine-as-a-promising-protective-agent-in-humans-and-animals
#6
Adam Bownik, Zofia Stępniewska
Ectoine is a compatible water molecule-binding solute (osmoprotectant) produced by several bacterial species in response to osmotic stress and unfavourable environmental conditions. This amino acid derivative can accumulate inside cells at high concentrations without interfering with natural processes and can protect the cell against radiation or osmotic stress. This brief review presents the current state of knowledge about the effects of ectoine on animals and focuses on its practical use for enzyme stabilisation, human skin protection, anti-inflammatory treatment, inhibitory effects in neurodegenerative diseases, and other therapeutic potential in human or veterinary medicine...
December 1, 2016: Arhiv za Higijenu Rada i Toksikologiju
https://www.readbyqxmd.com/read/28033101/radon-measurements-in-well-and-spring-water-of-the-tuzla-area-bosnia-and-herzegovina
#7
Amela Kasić, Amira Kasumović, Feriz Adrović, Muhamed Hodžić
Investigations of natural radioactivity in water, air, and soil are conducted frequently and routinely. Exposure to high concentrations of natural radioactive radon gas can cause irradiation of respiratory organs, which can lead to lung cancer. This paper presents measurements of radon activity concentrations in dug wells and natural springs of the Tuzla area (Bosnia and Herzegovina), which ranged from 214 to 3702 mBq L-1. Our results have shown that the radon activity concentration did not exceed the EU reference level for radon in drinking water (100 Bq L-1)...
December 1, 2016: Arhiv za Higijenu Rada i Toksikologiju
https://www.readbyqxmd.com/read/28033100/air-sampling-by-pumping-through-a-filter-effects-of-air-flow-rate-concentration-and-decay-of-airborne-substances
#8
Marko Šoštarić, Branko Petrinec, Dinko Babić
This paper tackles the issue of interpreting the number of airborne particles adsorbed on a filter through which a certain volume of sampled air has been pumped. This number is equal to the product of the pumped volume and particle concentration in air, but only if the concentration is constant over time and if there is no substance decomposition on the filter during sampling. If this is not the case, one must take into account the inconstancy of the concentration and the decay law for a given substance, which is complicated even further if the flow rate through the filter is not constant...
December 1, 2016: Arhiv za Higijenu Rada i Toksikologiju
https://www.readbyqxmd.com/read/28033099/an-alternative-approach-to-studying-the-effects-of-zno-nanoparticles-in-cultured-human-lymphocytes-combining-electrochemistry-and-genotoxicity-tests
#9
Gina Branica, Marin Mladinić, Dario Omanović, Davor Želježić
Nanoparticle use has increased radically raising concern about possible adverse effects in humans. Zinc oxide nanoparticles (ZnO NPs) are among the most common nanomaterials in consumer and medical products. Several studies indicate problems with their safe use. The aim of our study was to see at which levels ZnO NPs start to produce adverse cytogenetic effects in human lymphocytes as an early attempt toward establishing safety limits for ZnO NP exposure in humans. We assessed the genotoxic effects of low ZnO NP concentrations (1...
December 1, 2016: Arhiv za Higijenu Rada i Toksikologiju
https://www.readbyqxmd.com/read/28033098/testing-the-associations-between-different-aspects-of-seafarers-employment-contract-and-on-board-internet-access-and-their-job-and-life-satisfaction-and-health
#10
Ana Slišković, Zvjezdan Penezić
The aim of this study was to test for associations between different aspects of contract and on-board internet access and seafarers' satisfaction and health. Altogether 298 Croatian seafarers, all officers, employed on cargo ships, with a minimum work experience of two years with their current shipping company, participated in an online survey. The questionnaire included sociodemographic items, questions relating to their employment contract and internet access, and measures of job satisfaction, life satisfaction, mental health, and gastrointestinal and cardiovascular symptoms...
December 1, 2016: Arhiv za Higijenu Rada i Toksikologiju
https://www.readbyqxmd.com/read/28033097/age-and-sex-differences-in-genome-damage-between-prepubertal-and-adult-mice-after-exposure-to-ionising-radiation
#11
Ranko Stojković, Aleksandra Fucic, Dušica Ivanković, Zoran Jukić, Petra Radulović, Josip Grah, Nenad Kovačević, Lovro Barišić, Božo Krušlin
The mechanisms that lead to sex and age differences in biological responses to exposure to ionising radiation and related health risks have still not been investigated to a satisfactory extent. The significance of sex hormones in the aetiology of radiogenic cancer types requires a better understanding of the mechanisms involved, especially during organism development. The aim of this study was to show age and sex differences in genome damage between prepubertal and adult mice after single exposure to gamma radiation...
December 1, 2016: Arhiv za Higijenu Rada i Toksikologiju
https://www.readbyqxmd.com/read/28033096/detection-of-heavy-metals-in-common-vegetables-at-vara%C3%A5-din-city-market-croatia
#12
Zvjezdana Stančić, Dinko Vujević, Ana Gomaz, Saša Bogdan, Dragutin Vincek
The present study was aimed at the estimation of heavy metal content in vegetables sold at the city market of one of the densely populated Croatian cities, Varaždin, and to establish the relationship between their levels and possible sources of contamination. Twenty-eight samples of the most common diet vegetables (red and white potato, onion, carrot, common bean, lettuce, and cabbage) were randomly bought at the market in September and October 2013. Using the atomic absorption spectrometry method, concentrations of nine heavy metals (As, Cd, Cr, Cu, Hg, Mn, Ni, Pb, and Zn) were measured in the selected samples...
December 1, 2016: Arhiv za Higijenu Rada i Toksikologiju
https://www.readbyqxmd.com/read/28033095/gastric-decontamination-in-aluminium-phosphide-poisoning-a-case-against-the-use-of-water-based-solutions
#13
Hossein Sanaei-Zadeh, Sayed Mahdi Marashi
No abstract text is available yet for this article.
December 1, 2016: Arhiv za Higijenu Rada i Toksikologiju
https://www.readbyqxmd.com/read/27749267/variations-in-lead-cadmium-arsenic-and-mercury-concentrations-during-honeybee-wax-processing-using-casting-technology
#14
Ivana Tlak Gajger, Marina Kosanović, Nina Bilandžić, Marija Sedak, Bruno Čalopek
Beeswax foundations are a necessary material in intensive modern beekeeping. Heavy metals can accumulate in these foundations for decades, as it is a common beekeeping practice to recycle wax. Beeswax samples were analysed using GFAAS for As, Cd, Pb, and Hg concentrations during the production of beeswax foundations using casting technology with a prolonged cooling and sedimentation phase. Significant differences were determined in the concentrations of As, Cd, Pb (p<0.01, all), and Hg (p<0.05) between the three levels of wax in a double-walled steel casting container and comb foundations (CF) during the processing stage...
September 1, 2016: Arhiv za Higijenu Rada i Toksikologiju
https://www.readbyqxmd.com/read/27749266/a-review-of-aluminium-phosphide-poisoning-and-a-flowchart-to-treat-it
#15
Behrooz Hashemi-Domeneh, Nasim Zamani, Hossein Hassanian-Moghaddam, Mitra Rahimi, Shahin Shadnia, Peyman Erfantalab, Ali Ostadi
The use of pesticides such as aluminium phosphide (AlP) has increased in the recent years and improved the quantity and quality of agricultural products in a number of developing countries. The downside is that AlP causes severe chronic and acute health effects that have reached major proportions in countries such as India, Iran, Bangladesh, and Jordan. Nearly 300,000 people die due to pesticide poisoning in the world every year. Poisoning with AlP accounts for many of these deaths. Unfortunately, at the same time, there is no standard treatment for it...
September 1, 2016: Arhiv za Higijenu Rada i Toksikologiju
https://www.readbyqxmd.com/read/27749265/occurrence-of-intersex-in-wild-freshwater-fish-in-slovenian-rivers-a-histological-evaluation
#16
Milka Vrecl, Vlasta Jenčič
The aim of this preliminary research was to establish if there are intersex occurrences in wild freshwater fish in Slovenian rivers and streams. In the first study we evaluated all fish species of both sexes obtained from the river Ljubljanica from its source to mouth. In the second study we focused on the rainbow trout (Oncorhynchus mykiss) and brown trout (Salmo trutta m. fario) males from 30 rivers and streams in different parts of Slovenia. The male gonads were histologically assessed for the presence of oocytes to determine the frequency and degree of intersex...
September 1, 2016: Arhiv za Higijenu Rada i Toksikologiju
https://www.readbyqxmd.com/read/27749264/mutagenic-and-carcinogenic-structural-alerts-and-their-mechanisms-of-action
#17
Alja Plošnik, Marjan Vračko, Marija Sollner Dolenc
Knowing the mutagenic and carcinogenic properties of chemicals is very important for their hazard (and risk) assessment. One of the crucial events that trigger genotoxic and sometimes carcinogenic effects is the forming of adducts between chemical compounds and nucleic acids and histones. This review takes a look at the mechanisms related to specific functional groups (structural alerts or toxicophores) that may trigger genotoxic or epigenetic effects in the cells. We present up-to-date information about defined structural alerts with their mechanisms and the software based on this knowledge (QSAR models and classification schemes)...
September 1, 2016: Arhiv za Higijenu Rada i Toksikologiju
https://www.readbyqxmd.com/read/27749263/phytoremediation-potential-of-wild-plants-growing-on-soil-contaminated-with-heavy-metals
#18
Vladica Čudić, Dragoslava Stojiljković, Aleksandar Jovović
Phytoremediation is an emerging technology that employs higher plants to cleanup contaminated environments, including metal-polluted soils. Because it produces a biomass rich in extracted toxic metals, further treatment of this biomass is necessary. The aim of our study was to assess the five-year potential of the following native wild plants to produce biomass and remove heavy metals from a polluted site: poplar (Populus ssp.), ailanthus (Ailanthus glandulosa L.), false acacia (Robinia pseudoacacia L.), ragweed (Artemisia artemisiifolia L...
September 1, 2016: Arhiv za Higijenu Rada i Toksikologiju
https://www.readbyqxmd.com/read/27749262/impact-of-meteorological-parameters-and-air-pollution-on-emergency-department-visits-for-cardiovascular-diseases-in-the-city-of-zagreb-croatia
#19
Sanja Pintarić, Ivan Zeljković, Gordana Pehnec, Višnja Nesek, Mislav Vrsalović, Hrvoje Pintarić
The aim of this study was to investigate whether nitrogen dioxide (NO2), ozone (O3), and certain meteorological conditions had an impact on cardiovascular disease (CVD)-related emergency department (ED) visits in the metropolitan area of Zagreb. This retrospective, ecological study included 20,228 patients with a cardiovascular disease as their primary diagnosis who were examined in the EDs of two Croatian University Hospitals, Sisters of Charity and Holy Spirit, in the study period July 2008-June 2010. The median of daily CVD-related ED visits during the study period was 28 and was the highest during winter...
September 1, 2016: Arhiv za Higijenu Rada i Toksikologiju
https://www.readbyqxmd.com/read/27749261/workplace-noise-exposure-and-serum-testosterone-in-men-enrolled-in-the-1999-2004-national-health-and-nutrition-examination-survey
#20
Angel M Dzhambov
There is compelling evidence from animal experiments that noise exposure suppresses testosterone in males by affecting the hypothalamic-pituitary-testicular axis. Virtually nothing is known about its effect in humans. Therefore, the aim of this study was to explore the association between occupational noise exposure and serum testosterone in a representative sample of the general population. The sample has been taken from the National Health and Nutrition Examination Survey (NHANES) data for the period between 1999 and 2004 and is limited to employed men aged 16-85+ years at the time...
September 1, 2016: Arhiv za Higijenu Rada i Toksikologiju
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