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Indian Journal of Tuberculosis

Kranti Garg, Varinder Saini
No abstract text is available yet for this article.
July 2018: Indian Journal of Tuberculosis
Kumar Shwetanshu Narayan, Manoj Kumar, Shivdutt Padhi, Mukesh Jain, Prachis Ashdhir, Rupesh Kumar Pokharna
Localized hepatic tuberculosis (TB) with or without bile duct involvement is a rare form of hepatobiliary tuberculosis; accounting for less than 1% of all tuberculous infections. We report an uncommon case of cholestatic jaundice with disseminated TB in an immunocompetent male who presented with simultaneous involvement of liver and biliary system.
July 2018: Indian Journal of Tuberculosis
Prateek Tiwari, Vandana Mahajan, Kanchan Muhrerkar
Extramedullary hematopoisis (EMH) normally occurs in fetal life, but it is pathological in later life and most of the time because of underlying marrow diseases. Sometimes EMH tissue can present with large masses which can cause compressive and constitutional symptoms. They can be wrongly diagnosed as malignancy and pulmonary tuberculosis. Here in this case report we are reporting a case with mediastinal EMH because of underlying mylofibrosis.
July 2018: Indian Journal of Tuberculosis
Sathya Vamsi Krishna, B Mallikarjunaswamy, Thomas Issac, S Srinivasalu
A 50-year-old woman presented with pain, swelling, and reduced range of motion of right knee joint since one year. Radiograph of knee joint revealed eccentric, expansile, geographic lytic lesion on the medial epiphyseal region of tibia mimicking giant cell tumor (GCT). She underwent minimally invasive biopsy, which was positive for acid-fast bacilli and revealed necrotizing chronic granulomatous lesion, diagnostic of tuberculosis (TB). This case emphasizes to consider tuberculosis arthritis as differential diagnosis when a case of destructive giant cell tumor is encountered...
July 2018: Indian Journal of Tuberculosis
Natalia Florina Buinoiu, Sabrina Ioana Enache, Bogdan Chirculescu, Octavian Enciu, Alina Elena Barbu, Monica Radu, Valeriu Gheorghita, Florin Alexandru Caruntu, Gheorghe Peltecu, Anca Maria Panaitescu
We present a case report of a young nulliparous woman that presented with progressive ascites, night sweats and weight loss. Clinical and para-clinical findings were not suggestive of pulmonary tuberculosis (TB) or other peritoneal conditions. A laparoscopy revealed important ascites and granulomatous peritoneal infiltration with normal genital anatomy. Tests for tuberculosis revealed primary peritoneal involvement in absence of pulmonary TB. This was a case of TB with primary and limited localization in the peritoneum...
July 2018: Indian Journal of Tuberculosis
Bernadette Dian Novita, Agung Pranoto, Wuryani, Endang Isbandiati Soediono, Ni Made Mertaniasih
Metformin (MET) has possibilities to be utilized as an adjunct of tuberculosis (TB) therapy for controlling the growth of Mycobacterium tuberculosis (M. tuberculosis). MET enhances the production of mitochondrial reactive oxygen species and facilitates phagosome-lysosome fusion; those mechanism are important in M. tuberculosis elimination. Moreover, MET-associated lactic acidosis (MALA) needs to be considered and the incidence of MALA in patients with type 2 DM-TB coinfection remains unknown. This result contributes much to our understanding about the clinical effect of MET use in type 2 DM-TB coinfection...
July 2018: Indian Journal of Tuberculosis
Ranjeet Kumar, Jaswant Rai, N C Kajal, Pushpa Devi
BACKGROUND: Ashwagandha (Withania somnifera Linn.) a rejuvenative herb has long been used as an immunomodulator in Indian subcontinent. As immunity plays an important role in pathogenesis and treatment of tuberculosis (TB), so role of W. somnifera as an adjuvant has been studied on selected parameter. METHOD: A randomized, double-blind placebo-control study was conducted in two groups of 60 newly diagnosed sputum smear positive pulmonary TB patients on Directly Observed Treatment - short course (DOTS) regime...
July 2018: Indian Journal of Tuberculosis
Bipan Chander Sarin, Keerat Sibia, Sahiba Kukreja
BACKGROUND: Although subclinical adrenal insufficiency has been documented in tuberculosis but it has been neglected in mainstream management of TB due to inconclusive data on its prevalence in TB. The fact that adrenal insufficiency may result not only in poor general condition of the patient but also sudden death due to adrenal crisis, makes it all the more important to address this issue seriously. In this non-randomized interventional study comprising of 100 cases of TB, our aim was to assess the adreno-cortical functions in patients with pulmonary TB (50 cases) and extra-pulmonary TB (50 cases) in an attempt to determine if there is any compromise of adrenal function...
July 2018: Indian Journal of Tuberculosis
Krishnaveni Viswanathan, P S Rakesh, Shibu Balakrishnan, A S Pradeep Kumar
Government of Kerala state had implemented a pilot project of the World Health Organisation recommended Practical Approach to Lung health (PAL) strategy, with an intention to improve the quality of diagnosis, treatment and management of common chronic respiratory diseases (CRD) in primary health care settings. The current study was done as a part of implementation of PAL pilot project and was intended to assess the benefits of PAL for the individual patients with CRDs accessing services from primary health institutions...
July 2018: Indian Journal of Tuberculosis
Amit Kumar Sharma, Neeraj Gupta, Dilip Kumar Kala, Tarun Patni, Ramakant Dixit, Satyadeep Verma, Arjun Chandran
AIMS AND OBJECTIVES: To determine the prevalence and pattern of resistance to second line drugs among multi drug resistant (MDR) tuberculosis patients being treated on category IV regimen. METHODOLOGY: This study was conducted at Department of Respiratory Medicine, J.L.N. Medical College, Ajmer in collaboration with IRL, STDC, Ajmer. Second line anti tubercular drug sensitivity for 398 multi drug resistant tuberculosis patients (between June-2015 and June-2016) was done to find out prevalence and pattern of resistance to second line drugs...
July 2018: Indian Journal of Tuberculosis
Catherina Zadeh, Loubna Tayara
AIM: Tuberculosis is a contagious disease caused by Mycobacterium tuberculosis. It represents, according to WHO, one of the most leading causes of death worldwide.1 BACKGROUND: Based on our regional conditions, such as Syrian immigration, poor nutritional status, are contributors for the development of the disease. METHODS: This was a retrospective analytical cross sectional study done to review all cases of tuberculosis newly diagnosed at RHUH during 10 years period (2005-2015)...
July 2018: Indian Journal of Tuberculosis
Chakrapani Chatla, Jyoti Jaju, Shanta Achanta, Rani Samyuktha, Suryaprakash Chakramahanti, Chetan Purad, Raju Chepuri, Sreenivas Achyutan Nair, Malik Parmar
BACKGROUND: India has the world's highest estimated burden of multi-drug-resistant tuberculosis (MDR-TB). While prevalence of MDR-TB is known to be 2-3% among new TB patients and 12-17% in previously treated patients, programmatic information on the extent of transmission of TB and MDR-TB among household contacts of known MDR-TB patients is scarce. Systematic screening of household contacts of all MDR-TB patients on treatment was implemented as an intervention in the states of Andhra Pradesh and Telangana states of India...
July 2018: Indian Journal of Tuberculosis
Denny John, Prabir Chatterjee, Shruti Murthy, Ramesh Bhat, Baba Maiyaki Musa
BACKGROUND: In India, multidrug-resistant tuberculosis (MDR-TB) patients are usually treated in hospitals. Decentralised care model, however, has been suggested as a possible alternative by the World Health Organization (WHO). In the "End TB Strategy", the WHO highlights, as one of the key targets for 2035, that 'no TB-affected families should face catastrophic hardship due to the tuberculosis'. Removal of financial barriers to health-care access and mitigation of catastrophic expenditures are therefore considered vital to achieve the universal health coverage (UHC) goal...
July 2018: Indian Journal of Tuberculosis
Ebrahim Eskandari-Nasab, Mehdi Moghadampour, Arezoo Tahmasebi, Abolghasem Asadi-Saghandi
BACKGROUND: Cytokines are fundamental elements in mediating and stimulating the immune response against tuberculosis (TB). Growing evidence indicated that polymorphisms in the interleukin-17 (IL-17) A and F genes are implicated in TB. OBJECTIVES: This meta-analysis was aimed to re-evaluate and update the relationship between IL-17A rs2275913 G/A and IL17F rs763780 T/C polymorphisms and TB risk. METHODS: Using inclusive searches of the PubMed, MEDLINE, EMBASE, Web of Science and Elsevier Science Direct, we identified outcome data from all articles estimating the association between IL-17 A and F polymorphisms and TB risk...
July 2018: Indian Journal of Tuberculosis
Sahana K S, Prakash R M Saldanha, Supriya Kushwah, Anitha S Prabhu
INTRODUCTION: In spite of having BCG vaccination and tuberculosis control program for the last 50 years, prevalence of tuberculosis continues to be high in India. Inadequate diagnostic methods, suboptimal treatment and monitoring, and the lack of vigilant reporting system are some of the contributing factors for the failure of TB control. OBJECTIVES: To know the current practices among local pediatricians regarding management of TB. MATERIALS AND METHODS: Field based cross sectional study...
July 2018: Indian Journal of Tuberculosis
Tarig M S Alnour
Tuberculosis is one of the global health problems, the estimated deaths due to TB was around 2 million in the year 2013. Failure in early diagnosis and providing suitable treatment leads to increase the prognosis of the disease. Smear microscopy is used in many countries as a primary diagnosis of TB especially in the district poor facility laboratories, where smear negative frequency is high. This review aimed to reflects the importance of smear negative tuberculosis as a source of infection and poor prognosis of TB treatment and prevention...
July 2018: Indian Journal of Tuberculosis
Deepak Gupta
No abstract text is available yet for this article.
July 2018: Indian Journal of Tuberculosis
Sunil D Khaparde, Devesh Gupta, Ranjani Ramachandran, Kiran Rade, Manu Easow Mathew, Jyoti Jaju
No abstract text is available yet for this article.
July 2018: Indian Journal of Tuberculosis
Sameer Sarswat, Deepak Sachan
No abstract text is available yet for this article.
April 2018: Indian Journal of Tuberculosis
Rahul R Prabhu Desai, Sanjivani Keny, Durga Lawande
Tubercular esophagocutaneous fistula is a rare entity with only about five cases reported so far. It can be as a result of primary involvement of esophagus by tuberculosis or due to spread of infection from adjacent structures like lungs or mediastinal lymph nodes. The fistula usually heals with initiation of antitubercular therapy and surgery is rarely required. Here we report a case of 65-year-old diabetic male who developed esophagocutaneous fistula secondary to caseation of mediastinal lymph nodes and was successfully treated with antitubercular treatment...
April 2018: Indian Journal of Tuberculosis
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