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Indian Journal of Tuberculosis

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https://www.readbyqxmd.com/read/29579437/intraventricular-tuberculoma-an-unusual-presentation-of-brain-tuberculosis
#1
LETTER
Sameer Sarswat, Deepak Sachan
No abstract text is available yet for this article.
April 2018: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/29579436/tubercular-esophagocutaneous-fistula-rare-case-report
#2
Rahul R Prabhu Desai, Sanjivani Keny, Durga Lawande
Tubercular esophagocutaneous fistula is a rare entity with only about five cases reported so far. It can be as a result of primary involvement of esophagus by tuberculosis or due to spread of infection from adjacent structures like lungs or mediastinal lymph nodes. The fistula usually heals with initiation of antitubercular therapy and surgery is rarely required. Here we report a case of 65-year-old diabetic male who developed esophagocutaneous fistula secondary to caseation of mediastinal lymph nodes and was successfully treated with antitubercular treatment...
April 2018: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/29579435/isoniazid-induced-early-onset-of-motor-dominant-neuropathy-and-treatment-with-high-dose-of-pyridoxine
#3
C R Choudhary, Jyoti Kumari, Manish Advani
No abstract text is available yet for this article.
April 2018: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/29579434/localized-hepatic-tuberculosis-presenting-as-severe-hypercalcemia
#4
Matheus Arrais Morais, Lorena Lane Cardoso Teixeira, Dennyse de Sousa Brandão Torres, Prócion Barreto da Rocha Klautau Neto, Amanda Machado Kahwage
Hypercalcemia might present itself in association with granulomatous diseases such as tuberculosis. We report a rare case of a 62-year-old man with hypercalcemia due to hepatic tuberculosis. The diagnosis was based on laparoscopic and a histopathological examination. After treatment with anti-tuberculosis medication, the patient's serum calcium levels were within normal limits. Tuberculosis needs to be excluded as a diagnosis in any febrile patient with hypercalcemia, especially in countries where tuberculosis is endemic...
April 2018: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/29579433/awareness-of-health-care-workers-patients-and-visitors-regarding-air-borne-infection-control-a-descriptive-study-from-a-tertiary-care-centre-in-kerala-southern-india
#5
P T James, Akhilesh Kunoor, P S Rakesh
Airborne infections are major public health concern especially in hospitals and public spaces in a highly populated country like India. Generating awareness about good infection control practices among common man and health care workers are important steps in curtailing transmission of air borne infections. In this study we were trying to assess the awareness of airborne infection control measures among patients, bystanders and healthcare workers in a tertiary care hospital at Kochi, Kerala. Self-administered questionnaire which included 10 questions for health care staff and 12 questions for lay men prepared on the basis of NAIC and NCDC guideline were given to the study participants...
April 2018: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/29579432/clinical-features-vary-by-the-aetiology-of-meningitis-in-hiv-seropositive-patients-a-four-year-study-from-a-tertiary-hospital-in-india
#6
Amalakanti Sridhar, Gajula Krishna Sagar
Meningitis is a serious infection of the nervous system associated with high mortality in Human Immunodeficiency Virus (HIV) seropositive individuals. Asian clinical studies describing meningitis in people living with HIV are scarce. We describe the clinical features of meningitis in 116 HIV seropositive patients from a tertiary hospital in India as a cross-sectional observational study. The mean age of the patients in our study was 35±9 years with 70.6% of them being men. Eighty-five percent of the patients had an altered sensorium during the illness...
April 2018: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/29579431/quality-of-life-of-diabetic-patients-with-smear-positive-ptb-in-southeastern-iran-a-cross-sectional-study-in-a-poor-region-of-iran
#7
Hosien Shahdadi, Morteza Salarzaee, Abbas Balouchi
BACKGROUND: The quality of life is an important indicator of quality of care in chronic diseases such as diabetes and TB. The present research is conducted with an aim to assess the Quality of Life of Diabetic Patients with Smear Positive PTB. METHODS: This cross-sectional study was conducted on 62 diabetic patients with smear positive PTB from January to May 2016 in a diabetes clinic in Zahedan city (southeast of Iran). A simple random sampling method was used in this study...
April 2018: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/29579430/expression-profile-of-cxcl12-chemokine-during-m-tuberculosis-infection-with-different-therapeutic-interventions-in-guinea-pig
#8
Krishan Dutta Rawat, Mamta Chahar, Nalini Srivastava, U D Gupta, M Natrajan, V M Katoch, Kiran Katoch, D S Chauhan
Mycobacterium indicus pranii (MIP) already established as an immune-modulator in mycobacterial infections generates immune response by acting on CXC chemokines. In the present study, the immunomodulatory effect of MIP in conjunction with chemotherapy against M.tb infection was evaluated by colony forming units (CFUs) following aerosol infection to guinea pig and by measuring CXCL12 chemokine expression using q-PCR and in situ RT-PCR. Different experimental groups included, infection (Rv), immunoprophylaxis (RvMw), chemotherapy (RvCh) and combination of immunoprophylaxis+chemotherapy (RvChMw) group and normal healthy (NH) group...
April 2018: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/29579429/tuberculosis-related-stigma-and-its-effect-on-the-delay-for-sputum-examination-under-the-revised-national-tuberculosis-control-program-in-india
#9
Arupkumar Chakrabartty, Pampa Basu, Kazi Monjur Ali, Aditi Kishore Sarkar, Debidas Ghosh
BACKGROUND: One major barrier to achieve goal of tuberculosis (TB) control program globally, is the stigma attached to the disease. Perceived stigma can delay sputum test in time. Delay will lead to spread of infection in the community. There is no scientific information available in India exactly looking into the association between delay in sputum examination and stigma. AIM: We conducted a study in rural West Bengal among persons with cough for 2 weeks or more to assess their level of stigma, its influence on delay for sputum test and identify factors those shape the level of stigma...
April 2018: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/29579428/socio-demographic-profile-and-outcome-of-tb-patients-registered-at-dtc-rewa-of-central-india
#10
Rohit Trivedi Rohit, Anjana Niranjan, Paharam Adhikari Pawan
BACKGROUND: Tuberculosis is a specific infectious disease caused by Mycobacterium tuberculosis. The disease is usually chronic with cardinal features such as persistent cough with or without expectoration, intermittent fever, and loss of appetite, weight loss, chest pain and hemoptysis. OBJECTIVE: (1) To assess the socio-demographic profile of the patients attending DOTS Center. (2) To assess outcome of treatment under DOTS Center. METHODOLOGY: This is a Prospective Longitudinal study conducted among the patients attending DOTS center of DTC located at S...
April 2018: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/29579427/factors-predicting-treatment-success-in-multi-drug-resistant-tuberculosis-patients-treated-under-programmatic-conditions
#11
A K Janmeja, Deepak Aggarwal, Ruchika Dhillon
BACKGROUND: Treatment success in multi-drug resistant tuberculosis under programmatic conditions has been far from satisfactory. Knowledge of the factors predicting treatment outcome can guide us to take appropriate corrective measures for better results. However, there is a scarcity of data on these predictors in Indian patients. The present study was sought to evaluate association of different patient and disease specific factors with treatment outcome in MDR-TB patients. METHODS: It was a retrospective study that involved evaluation of data of MDR-TB patients who were started on Cat-IV treatment between January 2012 and December 2014...
April 2018: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/29579426/prevalence-of-pulmonary-tuberculosis-among-adults-in-selected-slums-of-delhi-city
#12
Rohit Sarin, Vikram Vohra, U K Khalid, Prem Prakash Sharma, Vineet Chadha, M A Sharada
BACKGROUND: A survey was carried out to estimate the point prevalence of bacteriologically positive pulmonary tuberculosis (PTB) among persons ≥15 years of age residing in Jhuggi-Jhopri (JJ) colonies - urban slums in Delhi, India implementing Directly Observed Treatment strategy since 1998. METHODS: Among 12 JJ colonies selected by simple random sampling, persons having persistent cough for ≥2 weeks at the time of the survey or cough of any duration along with history of contact/currently on ant-TB treatment/known HIV positive were subjected to sputum examination - 2 specimens, by smear microscopy for Acid Fast Bacilli and culture for Mycobacterium tuberculosis...
April 2018: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/29579425/knowledge-of-private-practitioners-of-bangalore-city-in-diagnosis-treatment-of-pulmonary-tuberculosis-and-compliance-with-case-notification
#13
Bhoomika Bajaj Bhalla, V K Chadha, J Gupta, N Nagendra, P Praseeja, S M Anjinappa, J Ahmed, R K Srivastava, P Kumar
One hundred and twenty-nine qualified private practitioners (PPs) were assessed on their knowledge in diagnosis of pulmonary tuberculosis (PTB), treatment of a new drug sensitive PTB case and practices of case notification, using semi-structured questionnaire. About 20% had adequate knowledge of diagnosis, 29% of treatment regimen, 54% the need for Direct Observation Treatment and 57% about role of sputum smear examination in monitoring treatment response. Of 85 (68%) PPs who had diagnosed any TB case during last two years, 54 (64%) had practised notification...
April 2018: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/29579424/a-selective-and-sensitive-high-performance-liquid-chromatography-assay-for-the-determination-of-cycloserine-in-human-plasma
#14
A K Hemanth Kumar, Arun Kumar Polisetty, V Sudha, A Vijayakumar, Geetha Ramachandran
BACKGROUND: Cycloserine (CYC) is a second line antitubercular drug that is used for the treatment of multidrug resistant tuberculosis (MDR-TB) along with other antitubercular agents and is often used in developing countries. Monitoring CYC levels in plasma could be useful in the clinical management of patients with MDR-TB. A high performance liquid chromatography method for the determination of CYC in human plasma was developed. METHODS: The method involved extraction of the sample using solid phase extraction cartridges and analysis of the extracted sample using a reverse phase T3 column (150mm) and detection at 240nm with Photo Diode Array (PDA) detector...
April 2018: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/29579423/modalities-to-monitor-the-treatment-response-in-tuberculosis
#15
REVIEW
Ujjwala N Gaikwad, Nitin R Gaikwad
Considering the global epidemic of drug resistance in Mycobacterium tuberculosis, early and accurate diagnosis as well as prompt initiation of antitubercular therapy (ATT) forms the mainstay of tuberculosis control programs. Patients on ATT may develop treatment failure due to diverse reasons including emergence of drug resistance in the host during the course of therapy. Monitoring the timely response to treatment in such cases has a significant role in rapid identification of drug resistant strains and institution of change of regimen to further decrease the morbidity and mortality associated with the disease...
April 2018: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/29579422/too-little-too-late-waiting-for-tb-to-come
#16
REVIEW
L Masae Kawamura
There is a new paradigm that preventing tuberculosis (TB) and addressing the reservoir of latent TB infection in combination with curing all TB cases is essential to accelerate the decline of TB rates and ending TB by 2050. However, complacency and incremental change eludes radical policy transformation needed to meet global targets. This essay explores current attitudes, policy disparities between high and lower burden settings, and what changes are needed to remove the obstacles to progress.
April 2018: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/29579421/inflammation-plays-a-central-role-in-respiratory-diseases-including-tuberculosis
#17
EDITORIAL
V K Arora, K K Chopra
No abstract text is available yet for this article.
April 2018: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/29332661/soft-tissue-tuberculosis-an-unusual-presentation-of-a-common-disease
#18
LETTER
Indu Manicketh, Poonam Panjwani, Gayatri Ravikumar, Leo Prince Mathan
Tuberculosis (TB) has reached epidemic proportions in India with a myriad of clinical presentations. Extra pulmonary TB can present in a wide variety of clinical forms and its identification requires a high degree of clinical suspicion. Soft tissue infection by Mycobacteria is rare. The diagnosis is often not thought of owing to the rarity of this entity.
January 2018: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/29332660/is6110-pcr-for-the-early-diagnosis-of-paediatric-tuberculosis-in-india
#19
LETTER
Ajay Vir Singh
No abstract text is available yet for this article.
January 2018: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/29332659/a-case-of-hepatic-tuberculosis-a-tuberculoma
#20
Sameer Khanijo, Pragati Tandon
Tuberculosis (TB) is a common cause of morbidity and mortality worldwide and its eradication in the United States has stalled for the first time in decades. Isolated hepatic TB is an extremely uncommon form of extrapulmonary TB. Here we present a case of a tuberculous liver abscess and suggest that TB should be considered in patients who fail to respond to antibiotics and prompt diagnostic intervention.
January 2018: Indian Journal of Tuberculosis
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