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Indian Journal of Tuberculosis

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https://www.readbyqxmd.com/read/29332661/soft-tissue-tuberculosis-an-unusual-presentation-of-a-common-disease
#1
LETTER
Indu Manicketh, Poonam Panjwani, Gayatri Ravikumar, Leo Prince Mathan
Tuberculosis (TB) has reached epidemic proportions in India with a myriad of clinical presentations. Extra pulmonary TB can present in a wide variety of clinical forms and its identification requires a high degree of clinical suspicion. Soft tissue infection by Mycobacteria is rare. The diagnosis is often not thought of owing to the rarity of this entity.
January 2018: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/29332660/is6110-pcr-for-the-early-diagnosis-of-paediatric-tuberculosis-in-india
#2
LETTER
Ajay Vir Singh
No abstract text is available yet for this article.
January 2018: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/29332659/a-case-of-hepatic-tuberculosis-a-tuberculoma
#3
Sameer Khanijo, Pragati Tandon
Tuberculosis (TB) is a common cause of morbidity and mortality worldwide and its eradication in the United States has stalled for the first time in decades. Isolated hepatic TB is an extremely uncommon form of extrapulmonary TB. Here we present a case of a tuberculous liver abscess and suggest that TB should be considered in patients who fail to respond to antibiotics and prompt diagnostic intervention.
January 2018: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/29332658/an-extremely-rare-association-of-sweet-s-syndrome-with-active-pulmonary-tuberculosis
#4
Sandhya Chauhan
Sweet's syndrome is a skin manifestation of various systemic infections, drugs, malignancies and autoimmune disorders. There are very few case reports describing the relationship between Sweet's syndrome and non-tubercular mycobacterium infection. Further development of Sweet's syndrome secondary to mycobacterium tuberculosis (active pulmonary tuberculosis) is extremely uncommon and this is the second well established case reported from India. Here we report a forty eight year old man who presented with multiple erythematous and tender plaques over neck, palms and sides of soles...
January 2018: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/29332657/primary-oral-tuberculosis-on-the-tongue-mimicking-squamous-cell-carcinoma
#5
Karandeep Singh Arora, Sunny Garg, Prabhpreet Kaur, Shreeyam Mohapatra
Tuberculosis is chronic granulomatous disease with rare oral manifestations. But if so are overlooked by most of the health care professionals. Clinically, most of the times, a tuberculous ulcer may mimic an ulcer of malignant origin and may be misdiagnosed. So, keeping in mind the etiology and the nature of the ulcer, it should be differentially diagnosed and a histopathological examination should only confirm the final diagnosis of the ulcer.
January 2018: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/29332656/germ-cell-tumor-causing-pleural-effusion-a-diagnostic-dilemma
#6
Surabhi Jaggi, Reetu Kundu, Sanjeev Binji, Uma Handa, Varinder Saini
Straw colored pleural fluid with raised adenosine deaminase (ADA) levels in young healthy adults usually raises suspicion of tuberculosis, sometimes leading to laxity in carrying thorough physical examination and missing out some important clues with potential disastrous consequences. A 35-year-old male was diagnosed to have left pleural effusion and anti-tubercular treatment was started on the basis of straw colored, lymphocyte-predominant pleural fluid with significantly raised ADA levels. When there was no improvement after 1 month of treatment he was investigated further and found to have a mediastinal mass along with hydro-pneumothorax...
January 2018: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/29332655/research-on-tuberculosis-in-tribal-areas-in-india-a-systematic-review
#7
REVIEW
V G Rao, M Muniyandi, J Bhat, R Yadav, R Sharma
BACKGROUND: Tuberculosis (TB) remains a major public health problem in resource-poor countries including India. Scientific knowledge is used to guide policy and practice. There is however, a limited, systematically collected data required for guiding the scale-up of interventions particularly amongst vulnerable populations including tribal groups in the country. In view of this, a systematic review of the TB research studies carried out in tribal areas of different parts of the country was undertaken...
January 2018: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/29332654/evaluation-of-loop-mediated-isothermal-amplification-lamp-assay-in-the-diagnosis-of-tubercular-lymphadenitis-a-pilot-study
#8
Baijayantimala Mishra, Vinaykumar Hallur, Bijayini Behera, C Preetam, Priti Nanda Mishra, Jyotirmayee Turuk, Prasanta Raghab Mohapatra
Tubercular lymphadenitis (TBLA) contributes to 30-40% of extrapulmonary TB cases in the immunocompetent individuals and 40-50% in people with HIV. Current diagnostic methods for TBLA like Gene-Xpert or PCR are costly and conventional methods like fine needle aspiration cytology, histopathology lack sensitivity and specificity. Culture which is considered as gold standard require high turnaround time. Loop mediated isothermal amplification (LAMP) assay has been developed as a novel technique for nucleic acid amplification and has shown promising results in the diagnosis of pulmonary tuberculosis...
January 2018: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/29332653/efficacy-of-alternate-day-directly-observed-treatment-short-course-dots-in-skeletal-tuberculosis-a-retrospective-study
#9
Rajat Chopra, Rama Bhatt, S K Biswas, R Bhalla
OBJECTIVE: To assess the efficacy of alternate day (thrice a week) Directly Observed Treatment Short-course (DOTS) regimen spanning six to nine months in providing sustained cure for skeletal tuberculosis (TB) under programmatic conditions. DESIGN: Retrospective cohort study. SETTING: An urban district tuberculosis centre in India under the Revised National Tuberculosis Programme. PARTICIPANTS: A cohort of 218 patients treated with alternate day DOTS regimen for skeletal TB between 2007 and 2012...
January 2018: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/29332652/initial-airflow-obstruction-in-new-cases-of-pulmonary-tuberculosis-complication-comorbidity-or-missed
#10
Andrii Dudnyk, Svitlana Blyzniuk, Oleksandr Pavel'chuk, Olena Zakharchenko, Dmytro Butov, SergiŃ– ZaŃ–kov
Tuberculosis (TB) may have a similar spirometry findings as a chronic obstructive pulmonary disease but the prevalence of TB-induced airflow obstruction (AO) is still unknown. OBJECTIVES: To measure frequency of AO in new TB cases at the beginning of treatment and to evaluate factors associated with obstructive abnormalities following TB diagnosis. MATERIALS AND METHODS: 317 patients that have no history of prior AO were recruited into the study with a median age of 39...
January 2018: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/29332651/koch-s-postulates-pitfalls-and-relevance-in-the-21st-century
#11
REVIEW
Surinder K Jindal
No abstract text is available yet for this article.
January 2018: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/29332650/amplification-of-hsp-65-gene-and-usage-of-restriction-endonuclease-for-identification-of-non-tuberculous-rapid-grower-mycobacterium
#12
Ajoy Kumar Verma, Rohit Sarin, Vijay Kumar Arora, Gavish Kumar, Jyoti Arora, Paras Singh, Vithal Prasad Myneedu
BACKGROUND: The rapid grower mycobacteria have emerged as significant group of human pathogen amongst the Runyon group IV organisms that are capable of causing infection in both the healthy and immunocompromised hosts. Study aimed to identification of species amongst rapid grower non tuberculous mycobacterial isolates by polymerase chain reaction - restriction enzyme analysis (PRA). Analysis and comparison of results with standard biochemical tests. METHODS: Rapid grower non tuberculous mycobacteria had been collected from liquid culture section during the study period...
January 2018: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/29332649/isoniazid-and-rifampicin-heteroresistant-mycobacterium-tuberculosis-isolated-from-tuberculous-meningitis-patients-in-india
#13
Renu Gupta, Rajeev Thakur, Suman Kushwaha, Nupur Jalan, Pumanshi Rawat, Piyush Gupta, Amitesh Aggarwal, Meena Gupta, Vikas Manchanda
BACKGROUND: Heteroresistant Mycobacterium tuberculosis (mixture of susceptible and resistant subpopulations) is thought to be a preliminary stage to full resistance and timely detection, initiation of correct treatment is vital for successful anti tubercular therapy. The aim of this study was to detect multi drug resistant (MDR) and heteroresistant M. tuberculosis with the associated gene mutations from patients of tuberculous meningitis. METHODS: A total of 197 M...
January 2018: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/29332648/prevalence-of-chronic-respiratory-diseases-from-a-rural-area-in-kerala-southern-india
#14
Krishnaveni Viswanathan, P S Rakesh, Shibu Balakrishnan, A Shanavas, Varun Dharman
BACKGROUND: Chronic lung diseases are one of the leading causes of morbidity in developing countries. A community based survey was undertaken with an objective to estimate the prevalence of chronic respiratory diseases and to describe the profile of people with CRDs in the rural area Nilamel health block in Kollam district, Kerala, southern India. METHODS: A household information sheet and a translated respiratory symptom questionnaire based on International Union against Tuberculosis and Lung Disease (IUATLD) bronchial symptoms questionnaire was administered to 12,556 people above 15 years, selected randomly from Nilamel health block...
January 2018: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/29332647/social-support-a-key-factor-for-adherence-to-multidrug-resistant-tuberculosis-treatment
#15
R D Deshmukh, D J Dhande, K S Sachdeva, A N Sreenivas, A M V Kumar, M Parmar
BACKGROUND: Multidrug-resistant tuberculosis (MDR-TB) is emerging as a major public health problem globally. Treatment success rates in MDR-TB across the globe are not encouraging as completing MDR-TB treatment successfully is challenging due to high proportion of lost to follow up. METHODS: Using qualitative methods and grounded theory approach, in-depth interviews were conducted with MDR-TB patients and treatment providers. The social cognitive framework was explored as a way to guide understanding of the factors affecting treatment adherence among MDR-TB patients...
January 2018: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/29332646/strategy-and-way-forward-for-tb-elimination
#16
REVIEW
Devesh Gupta
India's National Strategic Plan (NSP) for TB Elimination 2017-25 looks ambitious in terms of targets of TB notification aiming to reach 35 lakh TB patients annually, i.e. double that of current status. Strategies and interventions designed under the Plan with patient centered approaches, with synergistic public-private-patient partnership can make it possible to achieve real aim of reaching the unreached, by extending patient support systems and social protection to affected communities. In this review point, these strategies and commitments are summarized as future plan...
January 2018: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/29332645/plasma-levels-of-rifampicin-and-pyrazinamide-with-pre-and-post-meal-administration-in-tuberculosis-patients
#17
Parveen Kumar Sharma, Rekha Bansal, Ashok Kumar Bhardwaj, Vivek Sood, Atal Sood, Yogendra Padwad
CONTEXT: Various factors affect plasma concentrations of antitubercular drugs in different populations so dosing schedule should be adjusted after therapeutic drug monitoring. AIMS: To study variability in plasma concentrations of Rifampicin and Pyrazinamide with pre and post-meal administration of drugs in tuberculosis patients. METHODS AND MATERIAL: 52 patients of pulmonary tuberculosis, divided in to two groups, pre and post-meal through systemic randomization...
January 2018: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/29332644/role-of-serum-adenosine-deaminase-in-pulmonary-tuberculosis
#18
Varinder Saini, Bhaskar Lokhande, Shivani Jaswal, Deepak Aggarwal, Kranti Garg, Jasbinder Kaur
BACKGROUND: Definitive laboratory diagnosis and confirmation of tuberculosis remains a major challenge because of lack of specificity and sensitivity of diagnostic methods especially in sputum smear negative tuberculosis. Many studies have proved the role of ADA in diagnosis of tuberculosis in effusion fluids and a decrease in ADA activity after treatment. This study was aimed to investigate the role of serum ADA level as an early diagnostic and prognostic marker for pulmonary tuberculosis (PTB)...
January 2018: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/29332643/role-of-laparoscopy-in-diagnosing-genital-tuberculosis-in-suspected-women-a-cross-sectional-study-from-a-tertiary-care-hospital-in-northern-india
#19
Y M Mala, Ruchi Prasad, Nilanchali Singh, C P Baweja, Reva Tripathi, Niharika Yedla
This study was included 60 women with suspected genital tuberculosis, attending outpatient department of a tertiary care hospital. The aim was to evaluate the role and accuracy of laparoscopy in the diagnosis of genital tuberculosis. The patients were investigated for tuberculosis with Erythrocyte Sedimentation Rate, Montoux, chest X-ray, serum ELISA, CA125, ultrasonography, endometrial biopsy and laparoscopic biopsy. Culture or histopathology was taken as a gold standard for confirming the cases of genital tuberculosis...
January 2018: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/29332642/current-affairs-future-perspectives-of-tuberculosis-and-antitubercular-agents
#20
REVIEW
Jineetkumar Gawad, Chandrakant Bonde
Tuberculosis (TB) is the major threat for humans from past several decades. Even after advent of several antitubercular drugs, researchers are still struggling for the mycobacterial infections in humans are TB and leprosy. Chronic infections caused by Mycobacterium tuberculosis and Mycobacterium leprae. A particular problem with both of these organisms is that they can survive inside macrophages after phagocytosis, unless these cells are activated by cytokines produced by T-lymphocytes, because of this researchers are not yet succeeded in finding effective treatment on TB...
January 2018: Indian Journal of Tuberculosis
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