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Comprehensive Psychiatry

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https://www.readbyqxmd.com/read/29331882/association-analysis-of-slc6a4-and-htr2a-genes-with-obsessive-compulsive-disorder-influence-of-the-stin2-polymorphism
#1
Chayenne Karine Ferreira Gomes, Tamiris Vieira-Fonseca, Fernanda Brito Melo-Felippe, Juliana Braga de Salles Andrade, Leonardo F Fontenelle, Fabiana Barzotti Kohlrausch
BACKGROUND: Obsessive-Compulsive Disorder (OCD) is a complex and chronic disorder characterized by recurrent thoughts and/or repetitive behaviors. Given the potent anti-obsessional effects of the so-called serotonin reuptake inhibitors, genes related to serotonergic system may be well implicated in the etiopathogenesis of OCD. The gene encoding the serotonin transporter (SLC6A4), which shows a variable number of tandem repeat (VNTR) polymorphism in intron 2 (STin2), have been previously associated with OCD...
December 16, 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/29306067/maternal-ratings-of-odd-symptoms-subtypes-versus-severity-in-a-general-community-sample-of-children
#2
Rapson Gomez, Vasilis Stavropoulos
BACKGROUND AND AIMS: Oppositional Defiant Disorder (ODD) is a common childhood disorder (American Psychiatric Association [APA], 2000; APA, 2013). The aim of the present study was to ascertain the optimal structure for the ODD symptoms by identifying whether ODD is a qualitatively distinct entity (categorical) or is a continuum, with high levels on this continuum reflecting ODD (quantitative or dimensional view). METHODS: Mothers' ratings of the ODD symptoms of 457 children, aged 3 to 15years, as presented in the disruptive behavior rating scale were obtained...
December 8, 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/29278820/attachment-and-psychopathic-traits-in-inpatient-female-and-male-adolescents
#3
Malgorzata Gambin, Malgorzata Wozniak-Prus, Carla Sharp
No abstract text is available yet for this article.
November 28, 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/29268154/subthreshold-autism-spectrum-disorder-in-patients-with-eating-disorders
#4
L Dell'Osso, B Carpita, C Gesi, I M Cremone, M Corsi, E Massimetti, D Muti, E Calderani, G Castellini, M Luciano, V Ricca, C Carmassi, M Maj
AIM: Increasingly data suggest a possible overlap between psychopathological manifestations of eating disorders (EDs) and autism spectrum disorders (ASD). The aim of the present study was to assess the presence of subthreshold autism spectrum symptoms, by means of a recently validated instrument, in a sample of participants with EDs, particularly comparing participants with or without binge eating behaviours. METHODS: 138 participants meeting DSM-5 criteria for EDs and 160 healthy control participants (HCs), were recruited at 3 Italian University Departments of Psychiatry and assessed by the SCID-5, the Adult Autism Subthreshold Spectrum (AdAS Spectrum) and the Eating Disorders Inventory, version 2 (EDI-2)...
November 28, 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/29268153/current-prevalence-comorbidity-and-associated-factors-for-symptoms-of-depression-and-generalised-anxiety-in-the-lagos-state-mental-health-survey-lsmhs-nigeria
#5
Abiodun O Adewuya, Olayinka Atilola, Bolanle A Ola, Olurotimi A Coker, Mathew P Zachariah, Olufemi Olugbile, Adedolapo Fasawe, Olajide Idris
BACKGROUND: Depression and anxiety are very prevalent, highly co-morbid, burdensome with huge treatment gaps in low and middle-income countries (LMICs). This study aimed to estimate the current prevalence of symptoms of depression and generalised anxiety, examine co-morbid conditions and associated sociodemographic factors in Lagos state, Nigeria. METHODS: A face to face household survey completed by 11,246 adult participants (age 18-75years). Clinically significant symptoms of depression, generalised anxiety and somatic symptoms were assessed using the specific modules of the Patient Health Questionnaire (PHQ) respectively...
November 28, 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/29268152/self-reported-executive-function-and-hoarding-in-adults-with-obsessive-compulsive-disorder
#6
Jack Samuels, O Joseph Bienvenu, Janice Krasnow, Ying Wang, Marco A Grados, Bernadette Cullen, Fernando S Goes, Brion Maher, Benjamin D Greenberg, Nicole C McLaughlin, Steven A Rasmussen, Abby J Fyer, James A Knowles, James T McCracken, John Piacentini, Dan Geller, David L Pauls, S Evelyn Stewart, Dennis L Murphy, Yin-Yao Shugart, Mark A Riddle, Gerald Nestadt
BACKGROUND: Hoarding behavior may distinguish a clinically and possibly etiologically distinct subtype of obsessive-compulsive disorder (OCD). Little is known about the relationship between executive dysfunction and hoarding in individuals with OCD. METHODS: The study sample included 431 adults diagnosed with DSM-IV OCD. Participants were assessed by clinicians for Axis I disorders, personality disorders, indecision, and hoarding. Executive functioning domains were evaluated using a self-report instrument, the Behavior Rating Inventory of Executive Function-Adult Version (BRIEF-A)...
November 28, 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/29247962/vulnerability-to-exercise-addiction-socio-demographic-behavioral-and-psychological-characteristics-of-runners-at-risk-for-eating-disorders
#7
Laura Di Lodovico, Caroline Dubertret, Aurely Ameller
BACKGROUND: Excessive exercise is frequently associated with eating disorders and may degenerate into exercise addiction. We still don't know whether runners at risk for eating disorders are at risk for exercise addiction. Our aim is to assess: 1) risk for exercise addiction in runners at risk for eating disorders and 2) socio-demographic, behavioral and psychological characteristics distinguishing runners at-risk from not-at-risk for eating disorders. METHODS: We assessed risk for eating disorders and exercise addiction using the SCOFF questionnaire and the Exercise Addiction Inventory personality traits with the Big-Five Inventory Test, socio-demographic data, eating and training habits in a sample of 154 healthy runners...
November 28, 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/29245017/investigating-the-predictors-of-happiness-life-satisfaction-and-success-in-schizophrenia
#8
Sarah Saperia, Susana Da Silva, Ishraq Siddiqui, Krysta McDonald, Ofer Agid, Gary Remington, George Foussias
BACKGROUND: Previous studies have suggested that, despite marked functional impairments, remitted first episode patients with schizophrenia report levels of well-being that are comparable to healthy controls. The aim of the current study was to specifically evaluate self-reported happiness, life satisfaction and success in individuals with schizophrenia beyond their first-episode of psychosis, and to investigate the impact of symptoms and functioning on these subjective experiences. METHODS: Fifty-one schizophrenia patients and 56 matched healthy controls participated in the study...
November 22, 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/29222971/the-divergent-impact-of-catechol-o-methyltransferase-comt-val158met-genetic-polymorphisms-on-executive-function-in-adolescents-with-discrete-patterns-of-childhood-adversity
#9
Huihui Zhang, Jie Li, Bei Yang, Tao Ji, Zhouting Long, Qiquan Xing, Di Shao, Huayu Bai, Jiwei Sun, Fenglin Cao
PURPOSE: Catechol-O-methyltransferase (COMT) Val158Met functional polymorphisms play a crucial role in the development of executive function (EF), but their effect may be moderated by environmental factors such as childhood adversity. The present study aimed at testing the divergent impact of the COMT Val158Met genotype on EF in non-clinical adolescents with discrete patterns of childhood adversity. METHODS: A total of 341 participants completed the Childhood Trauma Questionnaire, the self-reported version of the Behavior Rating Inventory of Executive Function, and self-administered questionnaires on familial function...
November 22, 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/29195106/mental-health-of-caregivers-of-individuals-with-disabilities-relation-to-suicidal-ideation
#10
Yu-Chi Huang, Su-Ting Hsu, Chi-Fa Hung, Liang-Jen Wang, Mian-Yoon Chong
OBJECTIVE: The mental health of caregivers of individuals with disabilities is frequently neglected. This study investigated mental health status and Suicidal Ideation (SI) among caregivers and examined the predictive factors for SI. METHOD: Caregivers of individuals with physical or mental disabilities in a tertiary hospital in southern Taiwan were recruited through snowball sampling. They were assessed by self-report questionnaires, consisting of the Taiwanese Depression Questionnaire and a subset of the three-item Chinese Health Questionnaire, to assess probable depression and common mental disorders (CMDs), with cutoff points of 19 and 3, respectively...
November 14, 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/29195105/lgi1-antibody-encephalitis-detailed-clinical-laboratory-and-radiological-description-of-13-cases-in-china
#11
Dahai Wang, Qinjian Hao, Lingshuang He, Lan He, Qiang Wang
BACKGROUND AND PURPOSE: LGI1 antibody encephalitis is a synaptic autoimmune disorder that was first reported in 2010. To date, LGI1 antibody encephalitis is a widely-recognized disease in neurology and psychiatry. In order to aid clinical recognition of the condition, we analyze the clinical characteristics of 13 Chinese LGI1 antibody encephalitis patients. METHODS: We analyzed clinical features of patients admitted to the West China Hospital who had been diagnosed with LGI1 antibody encephalitis from 2015 to 2017...
November 14, 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/29195104/initial-psychometrics-outcomes-and-correlates-of-the-repetitive-body-focused-behavior-scale-examination-in-a-sample-of-youth-with-anxiety-and-or-obsessive-compulsive-disorder
#12
Robert R Selles, Valérie La Buissonnière Ariza, Nicole M McBride, Julie Dammann, Stephen Whiteside, Eric A Storch
BACKGROUND: Body-Focused Repetitive Behaviors (BFRBs), including skin-picking, hair-pulling, and nail-biting, commonly occur in youth, even at elevated/problematic levels, and are associated with a number of other psychiatric symptoms. The present study examined the internal consistency of a brief screening tool for BFRBs as well as the prevalence, severity, and correlates of BFRBs in a sample of youth with a primary anxiety or obsessive-compulsive disorder (OCD). METHODS: Ninety-three youth-parent dyads presenting for treatment for anxiety or OCD completed study measures including the Repetitive Body Focused Behavior Scale - Parent (RBFBS), which includes subscales for skin-picking, hair-pulling, and nail-biting, as well as a number of additional clinician-, parent-, and child-rated scales...
November 7, 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/29220641/coronary-vascular-disease-event-risk-and-metabolic-syndrome-prevalence-in-patients-enrolled-in-an-assertive-treatment-community-program
#13
Luis Ramudo Cela, María José Ávila González, Juan Carlos Yáñez Rubal, Lucía María Díaz Platas, María Isabel Martín Herranz, Juan Carlos Díaz Del Valle
OBJECTIVE: To examine the risk of coronary vascular disease event (CVDE) and the prevalence metabolic syndrome (MS) and its cardiovascular risk factors (CVRF) in patients with severe mental illnesses enrolled in an assertive treatment community program (ATC) in Spain. METHOD: We carried out a cross-sectional descriptive study with all of the patients included in an ATC program in 2016 in a health area with 547,328 inhabitants in Galicia, Spain. We identified the CVRF in all the individuals, and calculated MS and 10-year CVDE...
November 2, 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/29175375/posttraumatic-growth-among-people-with-serious-mental-illness-psychosis-and-posttraumatic-stress-symptoms
#14
Yael Mazor, Marc Gelkopf, David Roe
Recent research has shown high rates of exposure to trauma among people with serious mental illness (SMI). In addition, studies suggest that psychosis and mental illness-related experiences can be extremely traumatic. While some individuals develop posttraumatic symptomatology related to these experiences, some appear to experience posttraumatic growth (PTG). Little is known, however, about PTG as a possible outcome among people who experienced psychosis as well as posttraumatic stress symptoms (PTSS). For further understanding of the relationship between PTSS and PTG among people with SMI who experienced psychosis, 121 participants were recruited from community mental health rehabilitation centers and administered trauma and psychiatric questionnaires...
October 28, 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/29121555/the-relationship-between-adhd-traits-and-sensory-sensitivity-in-the-general-population
#15
Maria Panagiotidi, Paul G Overton, Tom Stafford
Preliminary studies in children and adults with Attention Deficit Hyperactivity Disorder (ADHD) report both hypo-responsiveness and hyper-responsiveness to sensory stimuli, as well as problems modulating sensory input. As it has been suggested that those with ADHD exist at the extreme end of a continuum of ADHD traits, which are also evident in the general population, we investigated the link between ADHD and sensory sensitivity in the general population. Two online questionnaires measuring ADHD traits and sensory responsivity across various sensory domains were administered to 234 participants...
October 25, 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/29121554/age-of-onset-of-non-suicidal-self-injury-in-dutch-speaking-adolescents-and-emerging-adults-an-event-history-analysis-of-pooled-data
#16
Amarendra Gandhi, Koen Luyckx, Imke Baetens, Glenn Kiekens, Ellen Sleuwaegen, Ann Berens, Shubhada Maitra, Laurence Claes
OBJECTIVE: Non-Suicidal Self-Injury (NSSI) has emerged as an important mental-health concern. However, epidemiological features like age of onset of NSSI have remained understudied. Therefore, the current study investigated the distribution of age of onset of NSSI in pooled sample of Dutch-speaking adolescents and emerging adults using event history analysis. METHOD: Eleven datasets measuring age at first NSSI in community and clinical participants collected by researchers in the Dutch-speaking part of Belgium were pooled together...
October 20, 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/29145062/differentiating-multiple-vs-single-lifetime-suicide-attempters-with-bipolar-disorders-a-retrospective-study
#17
Chiara Arici, Laura Cremaschi, Cristina Dobrea, Matteo Vismara, Benedetta Grancini, Beatrice Benatti, Massimiliano Buoli, Shefali Miller, Terence A Ketter, A Carlo Altamura, Bernardo Dell'Osso
BACKGROUND: The risk of suicide in Bipolar Disorder (BD) has been estimated up to 20-30 times higher compared with the general population. Previous suicide attempts (SAs) represent a well-established risk factor for further attempts and for death by suicide in patients with psychiatric disorders. However, little is known about the socio-demographic and clinical profile of BD patients with a history of multiple SAs (MSAs). The present study sought to characterize BD patients with MSAs versus single suicide attempt (SSA) within a large Italian sample...
October 19, 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/28943035/advances-in-transdiagnostic-psychopathology-research-introduction-to-the-special-issue
#18
EDITORIAL
Nicholas R Eaton
No abstract text is available yet for this article.
November 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/28757148/transdiagnostic-psychiatric-disorder-risk-associated-with-early-age-of-menarche-a-latent-modeling-approach
#19
Jonathan M Platt, Natalie L Colich, Katie A McLaughlin, Dahsan Gary, Katherine M Keyes
BACKGROUND: Earlier age of pubertal maturation in females is associated with increased risk for mental health problems in adolescence, compared with on-time or later maturation. However, most investigations of pubertal timing and mental health consider risk for individual disorders and fail to account for comorbidity. A latent-modeling approach using a large, nationally representative sample could better explain the transdiagnostic nature of the consequences of early-onset puberty. METHODS: Data on age of menarche and mental disorders were drawn from a population-representative sample of adolescents (n=4925), ages 13-17...
November 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/28735709/interpersonal-problems-across-levels-of-the-psychopathology-hierarchy
#20
Jeffrey M Girard, Aidan G C Wright, Joseph E Beeney, Sophie A Lazarus, Lori N Scott, Stephanie D Stepp, Paul A Pilkonis
We examined the relationship between psychopathology and interpersonal problems in a sample of 825 clinical and community participants. Sixteen psychiatric diagnoses and five transdiagnostic dimensions were examined in relation to self-reported interpersonal problems. The structural summary method was used with the Inventory of Interpersonal Problems Circumplex Scales to examine interpersonal problem profiles for each diagnosis and dimension. We built a structural model of mental disorders including factors corresponding to detachment (avoidant personality, social phobia, major depression), internalizing (dependent personality, borderline personality, panic disorder, posttraumatic stress, major depression), disinhibition (antisocial personality, drug dependence, alcohol dependence, borderline personality), dominance (histrionic personality, narcissistic personality, paranoid personality), and compulsivity (obsessive-compulsive personality)...
November 2017: Comprehensive Psychiatry
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