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Biorheology

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https://www.readbyqxmd.com/read/28800301/simultaneous-assessment-of-blood-coagulation-and-hematocrit-levels-in-dielectric-blood-coagulometry
#1
Yoshihito Hayashi, Marc-Aurèle Brun, Kenzo Machida, Seungmin Lee, Aya Murata, Shinji Omori, Hidetoshi Uchiyama, Yoshinori Inoue, Toshifumi Kudo, Takahiro Toyofuku, Masayuki Nagasawa, Isao Uchimura, Tomomasa Nakamura, Takeshi Muneta
BACKGROUND: In a whole blood coagulation test, the concentration of any in vitro diagnostic agent in plasma is dependent on the hematocrit level but its impact on the test result is unknown. OBJECTIVE: The aim of this work was to clarify the effects of reagent concentration, particularly Ca2+, and to find a method for hematocrit estimation compatible with the coagulation test. METHODS: Whole blood coagulation tests by dielectric blood coagulometry (DBCM) and rotational thromboelastometry were performed with various concentrations of Ca2+ or on samples with different hematocrit levels...
August 8, 2017: Biorheology
https://www.readbyqxmd.com/read/28697553/impact-of-training-volume-and-intensity-on-rbc-nos-no-pathway-and-endurance-capacity
#2
Christina Koliamitra, Bastian Holtkamp, Philipp Zimmer, Wilhelm Bloch, Marijke Grau
BACKGROUND: Acute exercise increases red blood cell-nitric oxide synthase (RBC-NOS) activation and RBC deformability but the effect of regular training remains unclear. OBJECTIVE: To detect the chronic effect of enduring moderate and high intensity training on the RBC-NOS/NO pathway and to detect a relation between RBC deformability and endurance capacity. METHODS: 38 healthy male subjects were randomly assigned to one of three training groups: High Volume Training (HVT; 120-140 beats per minute (bpm)), High Intensity Training (HIT; 160-180 bpm) and Moderate Intensity Training (MIT; 140-160 bpm)...
July 3, 2017: Biorheology
https://www.readbyqxmd.com/read/28339395/effect-of-ovariectomy-and-sideritis-euboea-extract-administration-on-large-artery-mechanics-morphology-and-structure-in-middle-aged-rats
#3
Dimitrios P Sokolis, Constantinos A Dimitriou, Pavlos Lelovas, Nikolaos G Kostomitsopoulos, Ismene A Dontas
BACKGROUND: Arterial function is regulated by estrogen, but no consistent pattern of arterial mechanical remodeling in response to depleted estrogen levels is available. OBJECTIVE: To examine long-term effects of ovariectomy (OVX) on the mechanical properties, morphology, and histological structure of carotid artery in middle-aged rats and a potentially protective effect of Sideritis euboea extract (SID), commonly consumed as "mountain tea". METHODS: 10-month-old female Wistar rats were allocated into control (sham-operated), OVX, OVX+SID, and OVX+MALT (maltodextrin; excipient used for dilution of SID) groups...
March 20, 2017: Biorheology
https://www.readbyqxmd.com/read/27767961/osteoarthritic-synovial-fluid-and-correlations-with-protein-concentration
#4
Anwar Madkhali, Michael Chernos, Samin Fakhraei, Dana Grecov, Ezra Kwok
BACKGROUND: Osteoarthritis is a common, localized joint disease that causes pain, stiffness and reduced mobility. The effects of osteoarthritis on the extensional rheology of synovial fluid in the knees are not fully understood and consequently require further study. OBJECTIVE: The purpose of this work is to study the extensional rheology of osteoarthritic synovial fluid and to investigate a possible correlation between synovial fluid protein concentration and extensional rheology...
November 9, 2016: Biorheology
https://www.readbyqxmd.com/read/27767960/osteoarthritic-synovial-fluid-rheology-and-correlations-with-protein-concentration
#5
Anwar Madkhali, Michael Chernos, Dana Grecov, Ezra Kwok
BACKGROUND: Osteoarthritis is a common, localized joint disease that causes pain, stiffness and reduced mobility. Osteoarthritis is particularly common in the knees. The effects of osteoarthritis on the rheology of synovial fluid in the knees are not fully understood and consequently require further study. OBJECTIVE: The purpose of this study is to investigate the effects of protein content on synovial fluid shear rheology. A secondary study outcome will include study of the temperature dependence of synovial fluid behaviour...
November 9, 2016: Biorheology
https://www.readbyqxmd.com/read/27662271/biphasic-impairment-of-erythrocyte-deformability-in-response-to-repeated-short-duration-exposures-of-supraphysiological-subhaemolytic-shear-stress
#6
Antony P McNamee, Geoff D Tansley, Surendran Sabapathy, Michael J Simmonds
INTRODUCTION: Despite current generation mechanical assist devices being designed to limit shear stresses and minimise damage to formed elements in blood, severe secondary complications suggestive of impaired rheological functioning are still observed. At present, the precise interactions between the magnitude-duration of shear stress exposure and the deformability of red blood cells (RBC) remain largely undescribed for repeated subhaemolytic shear stress duty-cycles of less than 15 s...
November 9, 2016: Biorheology
https://www.readbyqxmd.com/read/27567747/the-effect-of-acute-and-short-term-normobaric-hyperoxia-on-hemorheologic%C3%A2-parameters
#7
Pinar Ulker
Backround:Possible toxic effects of hyperoxia have been reported previously. However, the number of studies investigating the influence of hyperoxia on blood cells is limited and there are no data regarding its hemorheological effects. OBJECTIVE: The aim of this study was to investigate the effects of acute hyperoxia, performed in human subjects at normal atmospheric pressure, on the rheological properties of blood. METHOD: The study was conducted with 12 brain death patients mechanically ventilated in the intensive care unit...
November 9, 2016: Biorheology
https://www.readbyqxmd.com/read/27472843/large-artery-biomechanical-geometrical-and-structural-remodeling-elicited-by-long-term-propranolol-administration-in-an-animal-model
#8
Konstantinos M Lampropoulos, Dimitrios P Sokolis
BACKGROUND: Limited attention has been paid to the role of beta-adrenergic blocking agents on large artery function/structure, despite being clinically useful for treating many forms of cardiovascular disease. OBJECTIVE: To assess long-term consequences of beta-blocker administration on the biomechanical properties, geometry, and histological structure of two major elastic arteries. METHODS: Healthy male rats received water with their food, while beta-blockade was produced in rats by adding propranolol in their drinking water...
November 9, 2016: Biorheology
https://www.readbyqxmd.com/read/27472842/rheological-effects-of-macromolecular-interactions-in-synovial-fluid
#9
REVIEW
L Martin-Alarcon, T A Schmidt
The rheological properties of synovial fluid (SF) are largely attributed to the presence of high molecular weight hyaluronan (HA). However, rheological differences between SF and pure HA solutions suggest that SF proteins actively contribute towards the bulk viscoelasticity of this biological fluid. Due to various experimental challenges involved with the rheometry of low-viscosity biological fluids, the macromolecular interactions in SF and their relative rheological importance are still a matter of active discussion...
July 29, 2016: Biorheology
https://www.readbyqxmd.com/read/27472840/heterogeneous-phase-fibrinolysis-rates-by-damped-oscillation-rheometry
#10
Jae-Suk Lee, Makoto Kaibara, Edgar A O'Rear
BACKGROUND: Devices gauging viscoelastic properties of blood during coagulation like the thromboelastograph support fundamental research as well as point of care needs. Associated fibrinolysis data are based on endogenous species or plasminogen activator added to a homogeneous sample prior to clot formation. Digestion in a monolithic structure differs from the physical situation of thrombolytic therapy where surface reactions dominate. OBJECTIVE: This study aims to develop rheological testing for heterogeneous phase fibrinolysis...
July 29, 2016: Biorheology
https://www.readbyqxmd.com/read/27472841/relationship-between-arterial-blood-pressure-and-blood-viscosity-in-spontaneously-hypertensive-rats-treated-with-pentoxifylline
#11
Mark B Plotnikov, Oleg I Aliev, Alexey V Nosarev, Alexander Y Shamanaev, Anastasia V Sidekhmenova, Yana Anfinogenova, Anna M Anishchenko, Ekaterina V Pushkina
BACKGROUND: Systemic arterial pressure (AP) depends on two physiological variables: cardiac output (CO) and total peripheral resistance (TPR). The latter depends on vascular hindrance and blood viscosity (BV). However, the relative contributions of the vascular and rheological factors to TPR remain unclear. OBJECTIVE: The aim of our work was to study the haemodynamic and haemorheologic effects of a treatment course with pentoxifylline (PTX) in SHRs in an effort to assess the impact of the rheological factor on TPR and AP...
July 26, 2016: Biorheology
https://www.readbyqxmd.com/read/27392827/atrial-natriuretic-peptide-down-regulates-neutrophil-recruitment-on-inflamed-endothelium-by-reducing-cell-deformability-and-resistance-to-detachment-force
#12
Vasilios A Morikis, Chris Radecke, Yanyan Jiang, Volkmar Heinrich, Fitz-Roy Curry, Scott I Simon
No abstract text is available yet for this article.
July 4, 2016: Biorheology
https://www.readbyqxmd.com/read/27231840/optical-twisting-to-monitor-the-rheology-of-single-cells
#13
Matthieu Robert de Saint Vincent
BACKGROUND: Biological cells exhibit complex mechanical properties which determine their responses to applied force. OBJECTIVE: We developed an optical method to probe the temporal evolution of power-law rheology of single cells. METHODS: The method consisted in applying optically a constant mechanical torque to a birefringent microparticle bound to the cell membrane, and observing dynamics of the particle's in-plane rotation. RESULTS: The deformation dynamics of the membrane followed a power law of time, which directly relates to cytoskeletal prestress as reported in the literature...
May 26, 2016: Biorheology
https://www.readbyqxmd.com/read/26967951/deformation-and-rupture-of-dunaliella-salina-at-high-shear-rates-without-the-use-of-thickeners
#14
Dimitrios Kokkinos, Haider Dakhil, Andreas Wierschem, Heiko Briesen, André Braun
BACKGROUND: High-density cultures require operating below the critical threshold of shear stress, in order to avoid reducing the specific growth rate of the cells. When determining this threshold, direct inspection of the cells in flow provides insight into the conditions of shearing. OBJECTIVE: Aim of this study was using a novel rheo-optical setup for the observation of cells in laminar shear flow and the determination of the critical shear stress required to damage them in their natural environment...
March 10, 2016: Biorheology
https://www.readbyqxmd.com/read/26889656/the-expression-dynamics-of-mechanosensitive-genes-in-extra-embryonic-vasculature-after-heart-starts-to-beat-in-chick-embryo
#15
Saranya Rajendran, Lakshmikirupa Sundaresan, Krithika Rajendran, Monica Selvaraj, Ravi Gupta, Suvro Chatterjee
BACKGROUND: Fluid flow plays an important role in vascular development. However, the detailed mechanisms, particularly the link between flow and modulation of gene expression during vascular development, remain unexplored. In chick embryo, the key events of vascular development from initiation of heart beat to establishment of effective blood flow occur between the stages HH10 and HH13. Therefore, we propose a novel in vivo model to study the flow experienced by developing endothelium...
February 11, 2016: Biorheology
https://www.readbyqxmd.com/read/26889655/protective-effects-of-drag-reducing-polymers-in-a-rat-model-of-monocrotaline-induced-pulmonary-hypertension
#16
Yali Wang, Feng Hu, Xiaoyan Mu, Feng Wu, Dechun Yang, Guixiang Zheng, Xiaoning Sun, Kaizheng Gong, Zhengang Zhang
OBJECTIVES: Drag-reducing polymers (DRPs) are blood-soluble macromolecules which may increase blood flow and reduce vascular resistance. The purpose of the present study was to observe the effect of DRPs on monocrotaline-induced pulmonary hypertension (PH) in the rat model. METHODS: A total of 64 male Wistar rats were randomly divided into four groups: Group I (pulmonary hypertension model + DRP treatment); Group II (pulmonary hypertension model + saline treatment); Group III (control + DRP treatment); Group IV (control + saline treatment)...
January 27, 2016: Biorheology
https://www.readbyqxmd.com/read/26756280/hemorheological-effects-of-secoisolariciresinol-in-ovariectomized-rats
#17
Mikhail Y Maslov, Tatiana M Plotnikova, Anna M Anishchenko, Oleg I Aliev, Nikolay E Nifantiev, Mark B Plotnikov
BACKGROUND: Postmenopausal women often develop hemorheological disorders which may affect the systemic blood circulation and present a cardiovascular risk factor. OBJECTIVE: We evaluated effects of secoisolariciresinol (SECO), a phytoestrogen, on hemorheological parameters and lipid peroxidation in a model of the age-related and/or surgical menopause induced by ovariectomy in rats. METHODS: Arterial blood was sampled from sham-operated female rats, ovariectomized rats (OVX), and OVX treated with SECO (OVXSECO) (20 mg/kg/day intragastrically for two weeks)...
January 7, 2016: Biorheology
https://www.readbyqxmd.com/read/28372261/author-index-volume-53-2016
#18
(no author information available yet)
No abstract text is available yet for this article.
2016: Biorheology
https://www.readbyqxmd.com/read/28269737/the-autodigestion-hypothesis-proteolytic-receptor-cleavage-in-rheological-and-cardiovascular-cell-dysfunction1
#19
Geert W Schmid-Schönbein
Transformation of circulating leukocytes from a dormant into an activated state with changing rheological properties leads to a major shift of their behavior in the microcirculation. Low levels of pseudopod formation or expression of adhesion molecules facilitate relatively free passage through microvessels while activated leukocytes with pseudopods and enhanced levels of adhesion membrane proteins become trapped in microvessels, attach to the endothelium and migrate into the tissue. The transformation of leukocytes into an activated state is seen in many diseases...
2016: Biorheology
https://www.readbyqxmd.com/read/28222499/prediction-of-the-level-and-duration-of-shear-stress-exposure-that-induces-subhemolytic-damage-to-erythrocytes
#20
Michael J Simmonds, Herbert J Meiselman
BACKGROUND: Current generation mechanical circulatory assist devices are designed to minimize high shears to blood for prolonged durations to avoid hemolysis. However, red blood cells (RBC) demonstrate impaired capacity to deform when exposed to shear stress (SS) well below the "hemolytic threshold". OBJECTIVE: We endeavored to identify how changes in the magnitude and duration of SS exposure alter RBC deformability and subsequently develop a model to predict erythrocyte subhemolytic damage...
2016: Biorheology
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