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Documenta Ophthalmologica. Advances in Ophthalmology

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https://www.readbyqxmd.com/read/28332008/case-of-adult-onset-neuronal-intranuclear-hyaline-inclusion-disease-with-negative-electroretinogram
#1
Wataru Yamada, Akira Takekoshi, Kyoko Ishida, Kiyofumi Mochizuki, Jun Sone, Gen Sobue, Yuichi Hayashi, Takashi Inuzuka, Yozo Miyake
PURPOSE: To report the findings in a 72-year-old man with neuronal intranuclear hyaline inclusion disease (NIHID) with the negative-type electroretinogram (ERG) and without night blindness. METHODS: Standard ophthalmological examinations including the medical history, measurements of the best-corrected visual acuity and intraocular pressures, slit-lamp biomicroscopy, ophthalmoscopy, spectral-domain optical coherence tomography, fundus autofluorescence, and perimetry were performed...
March 22, 2017: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/28315987/early-postoperative-evaluation-of-retinal-function-by-electroretinography-after-vitreous-surgery-for-idiopathic-epimacular-membrane
#2
Akira Watanabe, Tamaki Gekka, Kota Arai, K Kohzaki, Hiroshi Tsuneoka
PURPOSE: In this study, we used the PuREC to carry out electroretinography (ERG) measurements using skin electrodes to assess changes before and after microincision vitreous surgery (MIVS) for epiretinal membrane (ERM) and evaluate the stress on retinal function soon after MIVS. METHODS: The study subjects were 18 eyes of 18 patients who underwent MIVS for ERM simultaneously with cataract surgery. ERG measurements were performed using a skin electrode on the day before vitreous surgery, on the day after surgery, and 1 week later...
March 18, 2017: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/28303363/test-retest-reliability-of-scotopic-full-field-electroretinograms-in-rabbits
#3
Jan Luebke, Alexandra Anton, Michael Bach
PURPOSE: To explore test-retest reliability of standard scotopic full-field ERG measurements in New Zealand White rabbits. The ERG is widely used for testing of retinal integrity after any ocular treatment. We here present detailed stimulus-response dependencies for single healthy and untreated animals, concentrating on test-retest reproducibility. MATERIALS AND METHODS: Five New Zealand White rabbits (aged 8-10 weeks, weight about 2.0-2.5 kg) underwent binocular ERG measurements after intramuscular anesthesia and pharmaceutical pupillary dilatation at a baseline day and 10 days later...
March 16, 2017: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/28281105/erratum-to-iscev-standard-for-clinical-electro-oculography-2017-update
#4
Paul A Constable, Michael Bach, Laura J Frishman, Brett G Jeffrey, Anthony G Robson
No abstract text is available yet for this article.
March 9, 2017: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/28281104/electroretinogram-and-visual-field-changes-in-a-case-of-birdshot-chorioretinopathy
#5
Hisham Elbaz, Volker Besgen, Klara Rechberger, Walter Sekundo, Eckart Apfelstedt-Sylla
PURPOSE: This case report explores the role of the visual field perimetry and electroretinogram (ERG) in cases of non-infectious uveitis in the assessment and monitoring of retinal function and response to treatment. METHODS: A 59-year-old Caucasian female presenting with bilateral posterior uveitis newly diagnosed as birdshot chorioretinopathy (BSCR) presenting with bilateral decrease in visual acuity and cystoid macular edema, as well as a paracentral scotoma in the right eye...
March 9, 2017: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/28243926/comparing-three-different-modes-of-electroretinography-in-experimental-glaucoma-diagnostic-performance-and-correlation-to-structure
#6
Laura Wilsey, Sowjanya Gowrisankaran, Grant Cull, Christy Hardin, Claude F Burgoyne, Brad Fortune
PURPOSE: To compare diagnostic performance and structure-function correlations of multifocal electroretinogram (mfERG), full-field flash ERG (ff-ERG) photopic negative response (PhNR) and transient pattern-reversal ERG (PERG) in a non-human primate (NHP) model of experimental glaucoma (EG). METHODS: At baseline and after induction of chronic unilateral IOP elevation, 43 NHP had alternating weekly recordings of retinal nerve fiber layer thickness (RNFLT) by spectral domain OCT (Spectralis) and retinal function by mfERG (7F slow-sequence stimulus, VERIS), ff-ERG (red 0...
February 27, 2017: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/28224239/the-importance-of-electrode-position-in-visual-electrophysiology
#7
A Kurtenbach, S Kramer, T Strasser, E Zrenner, H Langrová
PURPOSE: The DTL fibre electrode is commonly used to record the electric potentials elicited by stimulation of the retina. Two positions are commonly used: it is placed either on the cornea along the lower lid or in the conjunctival fornix. The PERG and OPs have previously been examined and compared under both conditions. The aim of this study was to examine the ERG, flicker response and on-off responses with differing electrode positions. METHODS: Before recruitment, all subjects underwent an ophthalmological examination...
February 21, 2017: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/28220265/similarities-and-differences-between-behavioral-and-electrophysiological-visual-acuity-thresholds-in-healthy-infants-during-the-second-half-of-the-first-year-of-life
#8
Claudia Polevoy, Gina Muckle, Jean R Séguin, Emmanuel Ouellet, Dave Saint-Amour
PURPOSE: Behavioral and electrophysiological methods for visual acuity estimation typically correlate well in children and adult populations, but this relationship remains unclear in infants, particularly during the second half of the first year of life. It has been suggested that the agreement between both methods mostly relies on age and/or subjective acuity factors. The present study aimed at comparing acuity thresholds obtained with both approaches in a sample of healthy infants in a relatively narrow age range, that is 6-10 months old...
February 20, 2017: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/28197754/differences-in-ocular-findings-in-two-siblings-one-with-complete-and-other-with-incomplete-achromatopsia
#9
Shinji Ueno, Ayami Nakanishi, Akira Sayo, Taro Kominami, Yasuki Ito, Takaaki Hayashi, Kazushige Tsunoda, Takeshi Iwata, Hiroko Terasaki
PURPOSE: Patients with complete achromatopsia (ACHM) lack cone function, and patients with incomplete ACHM have relatively good visual acuity with residual color vision. The pathological mechanism(s) underlying incomplete ACHM has not been determined. The purpose of this study was to determine the pathophysiology of ACHM in two siblings: one with complete ACHM and the other with incomplete ACHM. METHODS: The medical charts of the two siblings were reviewed. RESULTS: The sibling with incomplete ACHM had decimal visual acuities that ranged from 0...
February 14, 2017: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/28176172/evaluation-of-retinal-ganglion-cell-function-after-intraocular-pressure-reduction-measured-by-pattern-electroretinogram-in-patients-with-primary-open-angle-glaucoma
#10
Joanna Karaśkiewicz, Krzysztof Penkala, Maciej Mularczyk, Wojciech Lubiński
BACKGROUND: To evaluate retinal ganglion cell (RGC) function after intraocular pressure (IOP) reduction measured by pattern electroretinogram (PERG) in patients with newly diagnosed, non-treated preperimetric and early stages of primary open-angle glaucoma (POAG). METHODS: Twenty-four eyes from 24 patients with POAG: 11 eyes with preperimetric glaucoma and 13 eyes with early glaucoma received Ganfort (®) (bimatoprost + timolol) once a day for a period of 1 month...
February 7, 2017: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/28160194/constant-luminance-cd%C3%A2-s-m-2-versus-constant-retinal-illuminance-td%C3%A2-s-stimulation-in-flicker-ergs
#11
C Quentin Davis, Olga Kraszewska, Colette Manning
PURPOSE: To compare the effect of variable pupil size on the flicker electroretinogram (ERG) between a stimulus having constant luminance and a stimulus having constant retinal illuminance (constant Troland) that compensates for pupil size. METHODS: Subjects (n = 18) were tested with 12 pairs of the stimuli. The stimulus pair consisted of the ISCEV standard constant luminance stimulus (3 cd·s/m(2) with a 30 cd/m(2) background) and a constant retinal illuminance stimulus (32 Td·s with a 320 Td background) selected to provide the same stimulus and background when the pupil diameter is 3...
February 3, 2017: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/28144890/progressive-retinal-degeneration-in-a-girl-with-knobloch-syndrome-who-presented-with-signs-of-ocular-albinism
#12
Libe Gradstein, Ronald M Hansen, Gerald F Cox, Pablo Altschwager, Anne B Fulton
PURPOSE: We report for the first time electroretinographic (ERG) evidence of progressive retinal abnormalities in a girl who presented in infancy with ocular features of albinism and gradually developed choroidal sclerosis and patchy retinal atrophy leading to a diagnosis of Knobloch syndrome (KS, OMIM 267750, COL18A1). METHODS: At age 2 months, nystagmus and esotropia prompted ophthalmic evaluation. The appearance of choroidal sclerosis and atrophic retinal patches led to further evaluation at age 8 years...
January 31, 2017: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/28110380/iscev-standard-for-clinical-electro-oculography-2017-update
#13
Paul A Constable, Michael Bach, Laura J Frishman, Brett G Jeffrey, Anthony G Robson
The clinical electro-oculogram (EOG) is an electrophysiological test of the outer retina and retinal pigment epithelium (RPE) in which changes in the electrical potential across the RPE are recorded during successive periods of dark and light adaptation. This document presents the 2017 EOG Standard from the International Society for Clinical Electrophysiology of Vision (ISCEV: www.iscev.org ). This standard has been reorganized and updated to include an explanation of the mechanism of the EOG, but without substantive changes to the testing protocol from the previous version published in 2011...
February 2017: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/28091887/the-morphology-of-human-rod-ergs-obtained-by-silent-substitution-stimulation
#14
J Maguire, N R A Parry, J Kremers, I J Murray, D McKeefry
PURPOSE: To record transient ERGs from the light-adapted human retina using silent substitution stimuli which selectively reflect the activity of rod photoreceptors. We aim to describe the morphology of these waveforms and examine how they are affected by the use of less selective stimuli and by retinal pathology. METHODS: Rod-isolating stimuli with square-wave temporal profiles (250/250 ms onset/offset) were presented using a 4 primary LED ganzfeld stimulator...
February 2017: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/28074347/pattern-and-motion-related-visual-evoked-potentials-in-hiv-infected-adults
#15
Jana Szanyi, Jan Kremlacek, Zuzana Kubova, Miroslav Kuba, Pavel Gebousky, Jaroslav Kapla, Juraj Szanyi, Frantisek Vit, Jana Langrova
PURPOSE: The goal of the current study was to explore visual function in virally suppressed HIV patients undergoing combined antiretroviral therapy (cART) by using pattern-reversal and motion-onset visual evoked potentials (VEPs). METHODS: The pattern-reversal and motion-onset VEPs were recorded in 20 adult HIV+ patients with a mean age of 38 years and CD4 cell counts ≥230 × 10(6) cells/L of blood. RESULTS: Nine out of 20 patients displayed VEP abnormalities...
February 2017: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/28054161/the-relationship-of-nystagmus-waveform-on-the-vep-response-in-infantile-nystagmus-syndrome-a-small-case-series
#16
John P Kelly, James O Phillips, Avery H Weiss
PURPOSE: The relationship between eye movements and the visual evoked potential (VEP) response was examined in two subjects with infantile nystagmus syndrome (INS). Changes in VEP amplitude were compared between periods of foveation versus periods of high-frequency nystagmus. An analysis is proposed that improves extraction of the checkerboard reversal VEP signal from subjects with INS. METHODS: INS subjects were 2 healthy children (12-13 years old) with 20/40 or better corrected acuity...
February 2017: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/28035520/test-retest-reliability-of-the-multifocal-photopic-negative-response
#17
Anthony W Van Alstine, Suresh Viswanathan
PURPOSE: To assess the test-retest reliability of the multifocal photopic negative response (mfPhNR) of normal human subjects. METHODS: Multifocal electroretinograms were recorded from one eye of 61 healthy adult subjects on two separate days using a Visual Evoked Response Imaging System software version 4.3 (EDI, San Mateo, California). The visual stimulus delivered on a 75-Hz monitor consisted of seven equal-sized hexagons each subtending 12° of visual angle...
February 2017: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/28032236/efferent-influences-on-the-bioelectrical-activity-of-the-retina-in-primates
#18
REVIEW
Gonzalo Ortiz, J Vernon Odom, Christopher L Passaglia, Radouil T Tzekov
PURPOSE: The existence of retinopetal (sometimes referred to as "efferent" or "centrifugal") axons in the mammalian optic nerve is a topic of long-standing debate. Opposition is fading as efferent innervation of the retina has now been widely documented in rodents and other animals. The existence and function of an efferent system in humans and non-human primates has not, though, been definitively established. Such a feedback pathway could have important functional, clinical, and experimental significance to the field of vision science and ophthalmology...
February 2017: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/27838859/macular-function-in-preterm-children-at-school-age
#19
Hanna Åkerblom, Sten Andreasson, Gerd Holmström
PURPOSE: Macular development is a complex process that starts by mid-gestation and continues several years after birth. A preterm birth could affect this development, causing increased thickness in the central macula, but the effect of the macular function remains uncertain. The aim of this study was to investigate the macular function measured with multifocal electroretinography (mfERG), in former preterm children and compare with healthy controls. A second aim was to correlate central macular function with central macular thickness measured with optical coherent tomography (OCT), in the preterm group...
December 2016: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/27882486/vep-analysis-methods-in-children-with-optic-nerve-hypoplasia-relationship-to-visual-acuity-and-optic-disc-diameter
#20
John P Kelly, James O Phillips, Avery H Weiss
PURPOSE: Assessing vision in young children with optic nerve hypoplasia (ONH) is challenging due to multi-directional infantile nystagmus, the range of optic nerve loss, and cognitive delay. This study examined visual evoked potential (VEP) responses and averaging techniques in children with ONH. The assumption is that EEG epochs with inconsistent temporal phase would be associated with nystagmus, signal reduction due to axon loss, and visual inattention. METHODS: A retrospective chart review was performed on 44 children (average age 2...
November 23, 2016: Documenta Ophthalmologica. Advances in Ophthalmology
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