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Documenta Ophthalmologica. Advances in Ophthalmology

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https://www.readbyqxmd.com/read/29785579/56th-annual-symposium-of-the-international-society-for-clinical-electrophysiology-of-vision-iscev-2018
#1
(no author information available yet)
No abstract text is available yet for this article.
May 21, 2018: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/29779071/steady-state-perg-adaptation-a-conspicuous-component-of-response-variability-with-clinical-significance
#2
P Monsalve, S Ren, G Triolo, L Vazquez, A D Henderson, M Kostic, P Gordon, W J Feuer, V Porciatti
PURPOSE: To investigate within-test variability of the steady-state PERG (SS-PERG). METHODS: SS-PERGs were recorded in response to black-white horizontal gratings (1.6 cycles/deg, 98% contrast, 15.63 reversals/s, LED display, 25 deg square field, 800 cd/sqm mean luminance) using skin electrodes. PERG and noise (± reference) signals were averaged over 1024 epochs (~ 2.2 min) and Fourier analyzed to retrieve SS-PERG amplitude and phase. SS-PERGs were split into 16 partial averages (samples) of 64 epochs each, and corresponding amplitudes and phases combined in polar coordinates to assess their dispersion (within-test variability)...
May 19, 2018: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/29770905/congenital-grouped-albinotic-spots-of-the-retinal-pigment-epithelium-in-a-patient-with-hemihypertrophy-and-caf%C3%A3-au-lait-spots
#3
Eugenia C White, Jesse D Sengillo, Galaxy Y Cho, Mathieu F Bakhoum, Stephen H Tsang
PURPOSE: To describe the finding of circularly grouped hypomelanotic spots in the central macula of a patient with syndromic characteristics. METHODS: Case report of a patient with albinotic spots grouped within the macula, café au lait spots, and left-sided hemihypertrophy. RESULTS: A 15-year-old boy presented with hypomelanotic spots which were hyperautofluorescent on fundus autofluorescence imaging with no disruption of the retinal laminae or photoreceptor inner and outer segment (IS/OS) junction on spectral domain optical coherence tomography...
May 16, 2018: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/29770904/deferoxamine-induced-electronegative-erg-responses
#4
Ruben Jauregui, Karen Sophia Park, Alexander G Bassuk, Vinit B Mahajan, Stephen H Tsang
PURPOSE: To report a case of deferoxamine-induced retinopathy characterized by electroretinography (ERG), optical coherence tomography angiography (OCT-A), and other multimodal imaging. METHODS: This is an observational case report of one patient. Full-field ERG was performed. OCT-A, spectral-domain optical coherence tomography (SD-OCT), color fundus photography, and fundus autofluorescence were used to characterize the retinopathy induced by deferoxamine use. RESULTS: A 64-year-old man with a history of β-thalassemia intermedia presented with worsening visual acuity, nyctalopia, and electronegative ERG...
May 16, 2018: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/29766345/visual-function-assessed-by-visually-evoked-potentials-in-optic-pathway-low-grade-gliomas-with-and-without-neurofibromatosis-type-1
#5
Patrícia de Freitas Dotto, Adriana Berezovsky, Andrea Maria Cappellano, Nasjla Saba da Silva, Paula Yuri Sacai, Frederico Adolfo B Silva, Arthur Gustavo Fernandes, Daniel Martins Rocha, Solange Rios Salomão
PURPOSE: To investigate the contribution of full-field transient pattern-reversal visually evoked potentials (PRVEP) on cross-sectional evaluations of visual function in patients with and without neurofibromatosis type 1 (NF1) affected by optic pathway low-grade gliomas (OPLGG). METHODS: Participants were children and adolescents referred for visual function evaluation and receiving treatment for OPLGG, linked (NF1-OPLGG) or not to NF1 (Non-NF1-OPLGG). An age-adjusted control group was included for comparison...
May 15, 2018: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/29725862/ergs-on-the-brain-the-benefits-of-simultaneous-flash-retinal-and-cortical-responses-in-paediatric-cerebral-visual-impairment
#6
Sian E Handley, Dorothy A Thompson, Katrina L Prise, Alki Liasis
PURPOSE: To highlight the importance of simultaneous flash electroretinogram (ERG) and visual evoked potential (VEP) recording to differentiate a true flash VEP response from an artefact caused by the intrusion of the ERG on a mid-frontal reference electrode in cases of severe cerebral visual impairment (CVI). METHODS: We report an observational case series of four children with severe CVI who underwent simultaneous flash ERG and VEP recordings. Flash VEPs from Oz-Fz and lower lid skin ERGs referred to Fz were recorded simultaneously to Grass intensity setting 4 flash stimulation...
May 3, 2018: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/29691705/retinal-dysfunction-in-a-presymptomatic-patient-with-huntington-s-disease
#7
Jonelle Knapp, Dean A VanNasdale, Keith Ramsey, Julie Racine
PURPOSE: Huntington's disease (HD) is an autosomal dominant, neurodegenerative disorder characterized by progressive motor dysfunction, cognitive decline, and psychiatric disturbances. Studies have shown retinal abnormalities in patients and mouse models with HD; however, to our knowledge, no prior research papers evaluated retinal structure and function in a presymptomatic patient with HD. The aim of this report is to present a case of retinal dysfunction in a presymptomatic patient with HD...
April 24, 2018: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/29623523/visual-evoked-potentials-can-be-reliably-recorded-using-noninvasive-epidermal-electrodes-in-the-anesthetized-rat
#8
Roberto Santangelo, Valerio Castoldi, Raffaele D'Isa, Silvia Marenna, Su-Chun Huang, Marco Cursi, Giancarlo Comi, Letizia Leocani
PURPOSE: Visual evoked potentials (VEPs) are a powerful tool to evaluate nervous conduction along the visual pathways, both in humans and in animal models. Traditionally, epidural screw electrodes are used to record VEPs in preclinical research. Here we tested the feasibility in the preclinical setting of the same noninvasive technique used for clinical VEP acquisition, by using epidermal cup electrodes with no surgical procedures. METHODS: Monocular flash VEPs were recorded bilaterally under sevoflurane anesthesia once a week for 6 weeks in 14 dark Agouti rats, 7 with implanted epidural screws and 7 with epidermal 6 mm Ø Ag/AgCl cups...
April 5, 2018: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/29572760/comparison-between-albino-and-pigmented-rabbit-ergs
#9
Gabriela Lourençon Ioshimoto, Amanda Alves Camargo, André Maurício Passos Liber, Balázs Vince Nagy, Francisco Max Damico, Dora Fix Ventura
BACKGROUND: Pigmented and albino rabbits are commonly used in visual research; however, the lack of pigment in the eyes may affect retinal responses. Here, we compare and describe the differences of retinal function between pigmented (English Butterfly) and albino (New Zealand) rabbits. METHODS: Electroretinograms were recorded in pigmented and albino rabbits in the dark-adapted eye, in the light-adapted eye and for four temporal frequencies in the light-adapted eye...
March 23, 2018: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/29541898/correction-to-iscev-standard-for-clinical-electro-oculography-2017-update
#10
Paul A Constable, Michael Bach, Laura J Frishman, Brett G Jeffrey, Anthony G Robson
The article "ISCEV Standard for clinical electro-oculography (2017 update)", written by Paul A. Constable, Michael Bach, Laura J. Frishman, Brett G. Jeffrey, Anthony G. Robson and for the International Society for Clinical Electrophysiology of Vision, was originally published Online First without open access.
April 2018: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/29536324/comparison-between-multifocal-erg-and-c-scan-sd-oct-en-face-oct-in-patients-with-a-suspicion-of-antimalarial-retinal-toxicity-preliminary-results
#11
Carl Arndt, Mathieu Costantini, Christophe Chiquet, Mickael Afriat, Sylvie Berthemy, Vivien Vasseur, Alain Ducasse, Martine Mauget-Faÿsse
PURPOSE: Pericentral visual field changes and disruption of the ellipsoid layer on spectral domain optical coherence tomography (SD-OCT) are the main features of antimalarial retinal toxicity. C-Scan OCT or "en face" enables a topographic frontal view of the changes observed within the different retinal layers in particular the ellipsoid layer. The aim of this prospective study was to compare multifocal ERG (mfERG) responses with the results of C-Scan OCT ("en face" OCT) in patients with abnormal visual field and to analyze relationships between the structural and functional abnormalities...
April 2018: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/29525873/retinal-findings-in-a-patient-of-french-ancestry-with-cabp4-related-retinal-disease
#12
Vasily Mikhaïlovitch Smirnov, Christina Zeitz, Nagasamy Soumittra, Isabelle Audo, Sabine Defoort-Dhellemmes
INTRODUCTION: CABP4-related retinal dysfunction is a cone-rod synaptic transmission disorder with electronegative electroretinogram (ERG) waveform. It is a rare retinal dysfunction that can be classified into the incomplete form of congenital stationary night blindness. Absent foveal reflex and overall foveal thinning were previously reported, but in most cases the fundus appearance was described as nearly normal. We report here peculiar macular changes in a patient of French ancestry harbouring CABP4 mutations...
April 2018: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/29411205/phenotypic-expansion-and-progression-of-spata7-associated-retinitis-pigmentosa
#13
Jesse D Sengillo, Winston Lee, Colleen G Bilancia, Vaidehi Jobanputra, Stephen H Tsang
PURPOSE: To report an unusual phenotype of retinitis pigmentosa (RP) caused by compound heterozygous mutations in SPATA7, and describe the progression over a two year follow-up period. METHODS: Retrospective case study. RESULTS: A 63-year-old man with a long history of nyctalopia, progressive visual field constriction, and a recent subacute decrease in visual acuity of the left eye presented for evaluation of a suspected retinal degeneration...
April 2018: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/29372350/bilateral-vision-loss-due-to-leber-s-hereditary-optic-neuropathy-after-long-term-alcohol-nicotine-and-drug-abuse
#14
Johanna Maass, Egbert Matthé
PURPOSE: Leber's hereditary optic neuropathy is relatively rare, and no clinical pathognomonic signs exist. We present a rare case of bilateral vision loss of a patient with multiple drug abuse in the history. OBSERVATION: A 31-year-old man presented with a history of progressive, decreased vision in both eyes for 6 month. On examination, his visual acuity was hand motion in both eyes. Funduscopy demonstrated a temporal pallor of the optic disc. Goldmann visual field perimetry showed a crescent visual field in the right eye and a circular decrease to less than 50 ° in the left eye...
April 2018: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/29397523/iscev-guide-to-visual-electrodiagnostic-procedures
#15
Anthony G Robson, Josefin Nilsson, Shiying Li, Subhadra Jalali, Anne B Fulton, Alma Patrizia Tormene, Graham E Holder, Scott E Brodie
Clinical electrophysiological testing of the visual system incorporates a range of noninvasive tests and provides an objective indication of function relating to different locations and cell types within the visual system. This document developed by the International Society for Clinical Electrophysiology of Vision provides an introduction to standard visual electrodiagnostic procedures in widespread use including the full-field electroretinogram (ERG), the pattern electroretinogram (pattern ERG or PERG), the multifocal electroretinogram (multifocal ERG or mfERG), the electrooculogram (EOG) and the cortical-derived visual evoked potential (VEP)...
February 2018: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/29383474/retinopathy-from-hydroxychloroquine-is-not-related-to-lupus-or-rheumatoid-arthritis
#16
LETTER
Michael F Marmor
No abstract text is available yet for this article.
February 2018: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/29383473/response-to-risk-of-hydroxychloroquine-retinopathy-is-not-related-to-systemic-lupus-erythematosus-or-rheumatoid-arthritis
#17
LETTER
Nilufer Yesilirmak, Hande Husniye Telek, Gulten Sungur, Yaprak Ozdemir, Nesibe Karahan Yesil, Firdevs Ornek
No abstract text is available yet for this article.
February 2018: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/29139045/electroretinography-in-idiopathic-intracranial-hypertension-comparison-of-the-pattern-erg-and-the-photopic-negative-response
#18
COMPARATIVE STUDY
Jason C Park, Heather E Moss, J Jason McAnany
PURPOSE: To evaluate the relationship between electrophysiological measures of retinal ganglion cell (RGC) function in patients who have idiopathic intracranial hypertension (IIH). METHODS: The pattern electroretinogram (pERG) and photopic negative response (PhNR) were recorded from 11 IIH patients and 11 age-similar controls. The pERG was elicited by a contrast-reversing checkerboard. The PhNR, a slow negative component following the flash ERG b-wave, was recorded in response to a long-wavelength flash presented against a short-wavelength adapting field...
February 2018: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/29134296/p300-based-acuity-estimation-in-imitated-amblyopia
#19
Marvin L Beusterien, Sven P Heinrich
PURPOSE: A frequent approach to estimating visual acuity objectively is the recording of visual evoked potentials (VEPs) to patterns of different coarseness. This, however, overestimates acuity in patients with fragmented and distorted vision such as in amblyopia. This is likely due to VEP-based techniques using checkerboard or grating stimuli. We hypothesized that no overestimation would occur when the event-related potential P300 in response to optotype stimuli is used for acuity estimation...
February 2018: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/29134295/rod-versus-cone-driven-ergs-at-different-stimulus-sizes-in-normal-subjects-and-retinitis-pigmentosa-patients
#20
Avinash J Aher, Declan J McKeefry, Neil R A Parry, John Maguire, I J Murray, Tina I Tsai, Cord Huchzermeyer, Jan Kremers
PURPOSE: To study how rod- and cone-driven responses depend on stimulus size in normal subjects and patients with retinitis pigmentosa (RP), and to show that comparisons between responses to full-field (FF) and smaller stimuli can be useful in diagnosing and monitoring disorders of the peripheral retina without the need for lengthy dark adaptation periods. METHOD: The triple silent substitution technique was used to isolate L-cone-, M-cone- and rod-driven ERGs with 19, 18 and 33% photoreceptor contrasts, respectively, under identical mean luminance conditions...
February 2018: Documenta Ophthalmologica. Advances in Ophthalmology
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