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Documenta Ophthalmologica. Advances in Ophthalmology

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https://www.readbyqxmd.com/read/29987673/macular-staphyloma-in-patients-affected-by-joubert-syndrome-with-retinal-dystrophy-a-new-finding-detected-by-sd-oct
#1
Caterina Toma, Giulio Ruberto, Federico Marzi, Giulio Vandelli, Sabrina Signorini, Enza Maria Valente, Mauro Antonini, Chiara Bertone, Paolo Emilio Bianchi
PURPOSE: Joubert syndrome (JS) is an inherited autosomal recessive or X-lined disorder characterized by a congenital malformation of the mid-hindbrain and a large spectrum of clinical features. It is estimated that retinal dystrophy is present in association with the typical neurological findings in about one-third of the patients. The aim of this study is to better characterize the macular region in JS patients with and without retinal dystrophy. METHODS: We describe six individuals affected by JS as demonstrated by the presence of the typical "molar tooth sign" on MRI...
July 10, 2018: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/29968203/the-clinical-value-of-the-multi-channel-pvep-and-perg-in-the-diagnosis-and-management-of-the-patient-with-pituitary-adenoma-a-case-report
#2
Ewelina Lachowicz, Wojciech Lubiński
PURPOSE: To present a patient with a diagnosis of pituitary adenoma and progressive visual pathway dysfunction detected in the electrophysiological tests in one-year follow-up. Patient is a 59-year-old male with a non-secreting pituitary macroadenoma. METHODS: Routine ophthalmological evaluation, standard automatic perimetry (SAP), retinal nerve fibers layer and the ganglion cell complex thickness in optical coherent tomography (OCT), as well as electrophysiological examinations (pattern electroretinogram-PERG, multi-channel pattern visual evoked potentials-multi-channel PVEPs record according to ISCEV standards) were performed...
July 2, 2018: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/29934802/iscev-extended-protocol-for-the-photopic-on-off-erg
#3
Maja Sustar, Graham E Holder, Jan Kremers, Claire S Barnes, Bo Lei, Naheed W Khan, Anthony G Robson
The International Society for Clinical Electrophysiology of Vision (ISCEV) standard for full-field electroretinography (ERG) describes a minimum procedure, but encourages more extensive testing. This ISCEV extended protocol describes an extension to the ERG standard, namely the photopic On-Off ERG, and outlines common clinical applications. A light stimulus duration of 150-200 ms is used in the presence of a rod-suppressing background to elicit cone-driven On- and Off-system ERG components. The On-response occurs after the stimulus onset and has a negative a-wave and positive b-wave...
June 22, 2018: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/29934801/iscev-extended-protocol-for-the-dark-adapted-red-flash-erg
#4
Dorothy A Thompson, Kaoru Fujinami, Ido Perlman, Ruth Hamilton, Anthony G Robson
The International Society for Clinical Electrophysiology of Vision (ISCEV) standard for full-field electroretinography (ERG) describes a minimum procedure, but encourages more extensive testing. This ISCEV extended protocol describes an extension to the ERG standard, namely the dark-adapted (DA) red flash ERG. The DA red flash ERG can be incorporated conveniently within the ISCEV standard ERG protocol after a minimum of 20-min DA and recorded after the DA 0.01 ERG to a flash strength of 0.3 phot cd s m-2 , eliciting a waveform with two positive peaks in healthy individuals...
June 22, 2018: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/29881984/56th-annual-symposium-of-the-international-society-for-clinical-electrophysiology-of-vision-iscev-2018-reims-france-18-23-june-2018
#5
(no author information available yet)
No abstract text is available yet for this article.
June 7, 2018: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/29881983/iscev-2018-symposium-reims
#6
(no author information available yet)
No abstract text is available yet for this article.
June 7, 2018: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/29858967/dark-adapted-red-flash-ergs-in-healthy-adults
#7
R Hamilton, K Graham
PURPOSE: The x-wave of the dark-adapted (DA) ERG to a red flash reflects DA cone function. This exploratory study of healthy adults aimed to investigate changes in the DA red ERG with flash strength and during dark adaptation to optimise visualisation and therefore quantification of the x-wave. METHODS: The effect of altering red flash strength was investigated in four subjects by recording ERGs after 20 min dark adaptation to red flashes (0.2-2.0 cd s m-2 ) using skin electrodes and natural pupils...
June 1, 2018: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/29779071/steady-state-perg-adaptation-a-conspicuous-component-of-response-variability-with-clinical-significance
#8
P Monsalve, S Ren, G Triolo, L Vazquez, A D Henderson, M Kostic, P Gordon, W J Feuer, V Porciatti
PURPOSE: To investigate within-test variability of the steady-state PERG (SS-PERG). METHODS: SS-PERGs were recorded in response to black-white horizontal gratings (1.6 cycles/deg, 98% contrast, 15.63 reversals/s, LED display, 25 deg square field, 800 cd/sqm mean luminance) using skin electrodes. PERG and noise (± reference) signals were averaged over 1024 epochs (~ 2.2 min) and Fourier analyzed to retrieve SS-PERG amplitude and phase. SS-PERGs were split into 16 partial averages (samples) of 64 epochs each, and corresponding amplitudes and phases combined in polar coordinates to assess their dispersion (within-test variability)...
May 19, 2018: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/29770905/congenital-grouped-albinotic-spots-of-the-retinal-pigment-epithelium-in-a-patient-with-hemihypertrophy-and-caf%C3%A3-au-lait-spots
#9
Eugenia C White, Jesse D Sengillo, Galaxy Y Cho, Mathieu F Bakhoum, Stephen H Tsang
PURPOSE: To describe the finding of circularly grouped hypomelanotic spots in the central macula of a patient with syndromic characteristics. METHODS: Case report of a patient with albinotic spots grouped within the macula, café au lait spots, and left-sided hemihypertrophy. RESULTS: A 15-year-old boy presented with hypomelanotic spots which were hyperautofluorescent on fundus autofluorescence imaging with no disruption of the retinal laminae or photoreceptor inner and outer segment (IS/OS) junction on spectral domain optical coherence tomography...
May 16, 2018: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/29770904/deferoxamine-induced-electronegative-erg-responses
#10
Ruben Jauregui, Karen Sophia Park, Alexander G Bassuk, Vinit B Mahajan, Stephen H Tsang
PURPOSE: To report a case of deferoxamine-induced retinopathy characterized by electroretinography (ERG), optical coherence tomography angiography (OCT-A), and other multimodal imaging. METHODS: This is an observational case report of one patient. Full-field ERG was performed. OCT-A, spectral-domain optical coherence tomography (SD-OCT), color fundus photography, and fundus autofluorescence were used to characterize the retinopathy induced by deferoxamine use. RESULTS: A 64-year-old man with a history of β-thalassemia intermedia presented with worsening visual acuity, nyctalopia, and electronegative ERG...
May 16, 2018: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/29766345/visual-function-assessed-by-visually-evoked-potentials-in-optic-pathway-low-grade-gliomas-with-and-without-neurofibromatosis-type-1
#11
Patrícia de Freitas Dotto, Adriana Berezovsky, Andrea Maria Cappellano, Nasjla Saba da Silva, Paula Yuri Sacai, Frederico Adolfo B Silva, Arthur Gustavo Fernandes, Daniel Martins Rocha, Solange Rios Salomão
PURPOSE: To investigate the contribution of full-field transient pattern-reversal visually evoked potentials (PRVEP) on cross-sectional evaluations of visual function in patients with and without neurofibromatosis type 1 (NF1) affected by optic pathway low-grade gliomas (OPLGG). METHODS: Participants were children and adolescents referred for visual function evaluation and receiving treatment for OPLGG, linked (NF1-OPLGG) or not to NF1 (Non-NF1-OPLGG). An age-adjusted control group was included for comparison...
May 15, 2018: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/29725862/ergs-on-the-brain-the-benefits-of-simultaneous-flash-retinal-and-cortical-responses-in-paediatric-cerebral-visual-impairment
#12
Sian E Handley, Dorothy A Thompson, Katrina L Prise, Alki Liasis
PURPOSE: To highlight the importance of simultaneous flash electroretinogram (ERG) and visual evoked potential (VEP) recording to differentiate a true flash VEP response from an artefact caused by the intrusion of the ERG on a mid-frontal reference electrode in cases of severe cerebral visual impairment (CVI). METHODS: We report an observational case series of four children with severe CVI who underwent simultaneous flash ERG and VEP recordings. Flash VEPs from Oz-Fz and lower lid skin ERGs referred to Fz were recorded simultaneously to Grass intensity setting 4 flash stimulation...
May 3, 2018: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/29691705/retinal-dysfunction-in-a-presymptomatic-patient-with-huntington-s-disease
#13
Jonelle Knapp, Dean A VanNasdale, Keith Ramsey, Julie Racine
PURPOSE: Huntington's disease (HD) is an autosomal dominant, neurodegenerative disorder characterized by progressive motor dysfunction, cognitive decline, and psychiatric disturbances. Studies have shown retinal abnormalities in patients and mouse models with HD; however, to our knowledge, no prior research papers evaluated retinal structure and function in a presymptomatic patient with HD. The aim of this report is to present a case of retinal dysfunction in a presymptomatic patient with HD...
April 24, 2018: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/29855761/iscev-extended-protocol-for-the-photopic-negative-response-phnr-of-the-full-field-electroretinogram
#14
Laura Frishman, Maja Sustar, Jan Kremers, J Jason McAnany, Marc Sarossy, Radouil Tzekov, Suresh Viswanathan
The International Society for Clinical Electrophysiology of Vision (ISCEV) Standard for full-field electroretinography (ERG) describes a minimum procedure, but encourages more extensive testing. This ISCEV extended protocol describes an extension to the ERG Standard, namely the photopic negative response (PhNR) of the light-adapted flash ERG, as a well-established technique that is broadly accepted by experts in the field. The PhNR is a slow negative-going wave after the b-wave that provides information about the function of retinal ganglion cells and their axons...
June 2018: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/29785579/56th-annual-symposium-of-the-international-society-for-clinical-electrophysiology-of-vision-iscev-2018
#15
(no author information available yet)
No abstract text is available yet for this article.
June 2018: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/29623523/visual-evoked-potentials-can-be-reliably-recorded-using-noninvasive-epidermal-electrodes-in-the-anesthetized-rat
#16
Roberto Santangelo, Valerio Castoldi, Raffaele D'Isa, Silvia Marenna, Su-Chun Huang, Marco Cursi, Giancarlo Comi, Letizia Leocani
PURPOSE: Visual evoked potentials (VEPs) are a powerful tool to evaluate nervous conduction along the visual pathways, both in humans and in animal models. Traditionally, epidural screw electrodes are used to record VEPs in preclinical research. Here we tested the feasibility in the preclinical setting of the same noninvasive technique used for clinical VEP acquisition, by using epidermal cup electrodes with no surgical procedures. METHODS: Monocular flash VEPs were recorded bilaterally under sevoflurane anesthesia once a week for 6 weeks in 14 dark Agouti rats, 7 with implanted epidural screws and 7 with epidermal 6 mm Ø Ag/AgCl cups...
April 5, 2018: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/29572760/comparison-between-albino-and-pigmented-rabbit-ergs
#17
Gabriela Lourençon Ioshimoto, Amanda Alves Camargo, André Maurício Passos Liber, Balázs Vince Nagy, Francisco Max Damico, Dora Fix Ventura
BACKGROUND: Pigmented and albino rabbits are commonly used in visual research; however, the lack of pigment in the eyes may affect retinal responses. Here, we compare and describe the differences of retinal function between pigmented (English Butterfly) and albino (New Zealand) rabbits. METHODS: Electroretinograms were recorded in pigmented and albino rabbits in the dark-adapted eye, in the light-adapted eye and for four temporal frequencies in the light-adapted eye...
April 2018: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/29541898/correction-to-iscev-standard-for-clinical-electro-oculography-2017-update
#18
Paul A Constable, Michael Bach, Laura J Frishman, Brett G Jeffrey, Anthony G Robson
The article "ISCEV Standard for clinical electro-oculography (2017 update)", written by Paul A. Constable, Michael Bach, Laura J. Frishman, Brett G. Jeffrey, Anthony G. Robson and for the International Society for Clinical Electrophysiology of Vision, was originally published Online First without open access.
April 2018: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/29536324/comparison-between-multifocal-erg-and-c-scan-sd-oct-en-face-oct-in-patients-with-a-suspicion-of-antimalarial-retinal-toxicity-preliminary-results
#19
Carl Arndt, Mathieu Costantini, Christophe Chiquet, Mickael Afriat, Sylvie Berthemy, Vivien Vasseur, Alain Ducasse, Martine Mauget-Faÿsse
PURPOSE: Pericentral visual field changes and disruption of the ellipsoid layer on spectral domain optical coherence tomography (SD-OCT) are the main features of antimalarial retinal toxicity. C-Scan OCT or "en face" enables a topographic frontal view of the changes observed within the different retinal layers in particular the ellipsoid layer. The aim of this prospective study was to compare multifocal ERG (mfERG) responses with the results of C-Scan OCT ("en face" OCT) in patients with abnormal visual field and to analyze relationships between the structural and functional abnormalities...
April 2018: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/29525873/retinal-findings-in-a-patient-of-french-ancestry-with-cabp4-related-retinal-disease
#20
Vasily Mikhaïlovitch Smirnov, Christina Zeitz, Nagasamy Soumittra, Isabelle Audo, Sabine Defoort-Dhellemmes
INTRODUCTION: CABP4-related retinal dysfunction is a cone-rod synaptic transmission disorder with electronegative electroretinogram (ERG) waveform. It is a rare retinal dysfunction that can be classified into the incomplete form of congenital stationary night blindness. Absent foveal reflex and overall foveal thinning were previously reported, but in most cases the fundus appearance was described as nearly normal. We report here peculiar macular changes in a patient of French ancestry harbouring CABP4 mutations...
April 2018: Documenta Ophthalmologica. Advances in Ophthalmology
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