journal
MENU ▼
Read by QxMD icon Read
search

British Journal of Cancer

journal
https://www.readbyqxmd.com/read/29471308/reporting-guidelines-for-oncology-research-helping-to-maximise-the-impact-of-your-research
#1
REVIEW
Angela MacCarthy, Shona Kirtley, Jennifer A de Beyer, Douglas G Altman, Iveta Simera
Many reports of health research omit important information needed to assess their methodological robustness and clinical relevance. Without clear and complete reporting, it is not possible to identify flaws or biases, reproduce successful interventions, or use the findings in systematic reviews or meta-analyses. The EQUATOR Network (http://www.equator-network.org/) promotes responsible reporting and the use of reporting guidelines to improve the accuracy, completeness, and transparency of health research. EQUATOR supports researchers by providing online resources and training...
February 22, 2018: British Journal of Cancer
https://www.readbyqxmd.com/read/29471307/equator-oncology-reducing-the-latitude-of-cancer-trial-design-and-reporting
#2
EDITORIAL
Habeeb Majeed, Eitan Amir
No abstract text is available yet for this article.
February 22, 2018: British Journal of Cancer
https://www.readbyqxmd.com/read/29462132/development-of-a-prognostic-scoring-system-for-patients-with-advanced-cancer-enrolled-in-immune-checkpoint-inhibitor-phase-1-clinical-trials
#3
Shiraj Sen, Kenneth Hess, David S Hong, Aung Naing, Sarina Piha-Paul, Filip Janku, Siqing Fu, Ishwaria M Subbiah, Holly Liu, Rahil Khanji, Le Huang, Shhyam Moorthy, Daniel D Karp, Apostolia Tsimberidou, Funda Meric-Bernstam, Vivek Subbiah
BACKGROUND: We sought to develop a prognostic scoring system to aid in patient selection for immune checkpoint inhibitor (ICI) phase 1 clinical trials. METHODS: Clinical data from patients treated in phase 1 ICI clinical trials at MD Anderson (MDA) Center were analysed. Seventeen clinical factors were studied. Recursive partitioning analysis, a tree-based model, was used to develop a regression tree and identify optimal cut-points based on differences in survival for each clinical factor...
February 20, 2018: British Journal of Cancer
https://www.readbyqxmd.com/read/29462131/pathological-complete-response-and-prognosis-after-neoadjuvant-chemotherapy-for-her2-positive-breast-cancers-before-and-after-trastuzumab-era-results-from-a-real-life-cohort
#4
Anne-Sophie Hamy, Lisa Belin, Hélène Bonsang-Kitzis, Caroline Paquet, Jean-Yves Pierga, Florence Lerebours, Paul Cottu, Roman Rouzier, Alexia Savignoni, Marick Lae, Fabien Reyal
This corrects the article DOI: 10.1038/bjc.2015.426.
February 20, 2018: British Journal of Cancer
https://www.readbyqxmd.com/read/29462130/risk-of-cancer-in-patients-with-epistaxis-and-haemoptysis
#5
Anne G Ording, Katalin Veres, Dóra K Farkas, Kasper Adelborg, Henrik T Sørensen
BACKGROUND: Respiratory tract bleeding may be a marker of cancer. We quantified the risk of specific cancer types among patients with hospital-based diagnoses of epistaxis and haemoptysis relative to risk in the general population. METHODS: We used Danish, nationwide databases to conduct a population-based cohort study of 80460 patients diagnosed with epistaxis and 18487 patients presenting with haemoptysis (1995-2013). We followed patients until a cancer diagnosis, emigration, death, or 31 December 2013, whichever came first...
February 20, 2018: British Journal of Cancer
https://www.readbyqxmd.com/read/29462129/family-history-of-cancer-and-the-risk-of-childhood-solid-tumours-a-norwegian-nationwide-register-based-cohort-study
#6
Ruby Del Risco Kollerud, Karl Gerhard Blaasaas, Bjørgulf Claussen, Per Nafstad, Lisa A Cannon-Albright, Ellen Ruud, Finn Wesenberg, Øyvind Næss
BACKGROUND: It is not clear if family history of cancer increases risk of cancer in children. METHODS: We followed-up a total of 2 610 937 children born between 1960 and 2001 for cancer risk, and their parents and siblings. In this period, 2477 primary childhood solid tumours (except lymphoma) were diagnosed. The data from the Norwegian Family and Life Course Study and from the Norwegian Cancer Register were used. Classification of hereditary cancer syndromes was based on tumour histology, pedigrees and Chompret's criteria...
February 20, 2018: British Journal of Cancer
https://www.readbyqxmd.com/read/29462128/mir-146a-5p-mediates-epithelial-mesenchymal-transition-of-oesophageal-squamous-cell-carcinoma-via-targeting-notch2
#7
Cong Wang, Wenxue Zhang, Lin Zhang, Xuan Chen, Fang Liu, Jing Zhang, Shanghui Guan, Yi Sun, Pengxiang Chen, Ding Wang, Effat Un Nesa, Yufeng Cheng, George M Yousef
This corrects the article DOI: 10.1038/bjc.2016.367.
February 20, 2018: British Journal of Cancer
https://www.readbyqxmd.com/read/29462127/ex-vivo-metabolic-fingerprinting-identifies-biomarkers-predictive-of-prostate-cancer-recurrence-following-radical-prostatectomy
#8
Peder R Braadland, Guro Giskeødegård, Elise Sandsmark, Helena Bertilsson, Leslie R Euceda, Ailin F Hansen, Ingrid J Guldvik, Kirsten M Selnæs, Helene H Grytli, Betina Katz, Aud Svindland, Tone F Bathen, Lars M Eri, Ståle Nygård, Viktor Berge, Kristin A Taskén, May-Britt Tessem
This corrects the article DOI: 10.1038/bjc.2017.346.
February 20, 2018: British Journal of Cancer
https://www.readbyqxmd.com/read/29462126/plasticity-and-intratumoural-heterogeneity-of-cell-surface-antigen-expression-in-breast-cancer
#9
Ján Remšík, Radek Fedr, Jiří Navrátil, Lucia Binó, Eva Slabáková, Pavel Fabian, Marek Svoboda, Karel Souček
BACKGROUND: The intratumoural heterogeneity, often driven by epithelial-to-mesenchymal transition (EMT), significantly contributes to chemoresistance and disease progression in adenocarcinomas. METHODS: We introduced a high-throughput screening platform to identify surface antigens that associate with epithelial-mesenchymal plasticity in well-defined pairs of epithelial cell lines and their mesenchymal counterparts. Using multicolour flow cytometry, we then analysed the expression of 10 most robustly changed antigens and identified a 10-molecule surface signature, in pan-cytokeratin-positive/EpCAM-positive and -negative fractions of dissociated breast tumours...
February 20, 2018: British Journal of Cancer
https://www.readbyqxmd.com/read/29449676/the-improving-rural-cancer-outcomes-trial-a-cluster-randomised-controlled-trial-of-a-complex-intervention-to-reduce-time-to-diagnosis-in-rural-cancer-patients-in-western-australia
#10
Jon D Emery, Victoria Gray, Fiona M Walter, Shelley Cheetham, Emma J Croager, Terry Slevin, Christobel Saunders, Timothy Threlfall, Kirsten Auret, Anna K Nowak, Elizabeth Geelhoed, Max Bulsara, C D'Arcy J Holman
This corrects the article DOI: 10.1038/bjc.2017.310.
February 15, 2018: British Journal of Cancer
https://www.readbyqxmd.com/read/29449675/comment-on-prognostic-biomarkers-for-oral-tongue-squamous-cell-carcinoma-a-systematic-review-and-meta-analysis
#11
Rama Jayaraj, Chellan Kumarasamy
No abstract text is available yet for this article.
February 15, 2018: British Journal of Cancer
https://www.readbyqxmd.com/read/29449674/reply-to-comment-on-prognostic-biomarkers-for-oral-tongue-squamous-cell-carcinoma-a-systematic-review-and-meta-analysis
#12
Alhadi Almangush, Ilkka Heikkinen, Antti A Mäkitie, Ricardo D Coletta, Esa Läärä, Ilmo Leivo, Tuula Salo
No abstract text is available yet for this article.
February 15, 2018: British Journal of Cancer
https://www.readbyqxmd.com/read/29449673/the-predictive-and-prognostic-potential-of-plasma-telomerase-reverse-transcriptase-tert-rna-in-rectal-cancer-patients
#13
Enrica Rampazzo, Paola Del Bianco, Roberta Bertorelle, Caterina Boso, Alessandro Perin, Giovanna Spiro, Francesca Bergamo, Claudio Belluco, Angela Buonadonna, Elisa Palazzari, Sara Leonardi, Antonino De Paoli, Salvatore Pucciarelli, Anita De Rossi
BACKGROUND: Preoperative chemoradiotherapy (CRT) followed by surgery is the standard care for locally advanced rectal cancer, but tumour response to CRT and disease outcome are variable. The current study aimed to investigate the effectiveness of plasma telomerase reverse transcriptase (TERT) levels in predicting tumour response and clinical outcome. METHODS: 176 rectal cancer patients were included. Plasma samples were collected at baseline (before CRT=T0), 2 weeks after CRT was initiated (T1), post-CRT and before surgery (T2), and 4-8 months after surgery (T3) time points...
February 15, 2018: British Journal of Cancer
https://www.readbyqxmd.com/read/29438376/regulation-of-itga3-by-the-dual-stranded-microrna-199-family-as-a-potential-prognostic-marker-in-bladder-cancer
#14
Takashi Sakaguchi, Hirofumi Yoshino, Masaya Yonemori, Kazutaka Miyamoto, Satoshi Sugita, Ryosuke Matsushita, Toshihiko Itesako, Shuichi Tatarano, Masayuki Nakagawa, Hideki Enokida
This corrects the article DOI: 10.1038/bjc.2017.43.
February 13, 2018: British Journal of Cancer
https://www.readbyqxmd.com/read/29438375/telomere-length-and-genetics-are-independent-colorectal-tumour-risk-factors-in-an-evaluation-of-biomarkers-in-normal-bowel
#15
Ceres Fernandez-Rozadilla, Christiana Kartsonaki, Connor Woolley, Michael McClellan, Deb Whittington, Gareth Horgan, Simon Leedham, Skirmantas Kriaucionis, James East, Ian Tomlinson
BACKGROUND: Colorectal cancer (CRC) screening might be improved by using a measure of prior risk to modulate screening intensity or the faecal immunochemical test threshold. Intermediate molecular biomarkers could aid risk prediction by capturing both known and unknown risk factors. METHODS: We sampled normal bowel mucosa from the proximal colon, distal colon and rectum of 317 individuals undergoing colonoscopy. We defined cases as having a personal history of colorectal polyp(s)/cancer, and controls as having no history of colorectal neoplasia...
February 13, 2018: British Journal of Cancer
https://www.readbyqxmd.com/read/29438374/comment-on-30-years-follow-up-and-increased-risks-of-breast-cancer-and-leukaemia-after-long-term-low-dose-rate-radiation-exposure
#16
Mohan Doss
No abstract text is available yet for this article.
February 13, 2018: British Journal of Cancer
https://www.readbyqxmd.com/read/29438373/anlotinib-as-a-third-line-therapy-in-patients-with-refractory-advanced-non-small-cell-lung-cancer-a-multicentre-randomised-phase-ii-trial-alter0302
#17
Baohui Han, Kai Li, Yizhuo Zhao, Baolan Li, Ying Cheng, Jianying Zhou, You Lu, Yuankai Shi, Zhehai Wang, Liyan Jiang, Yi Luo, Yiping Zhang, Cheng Huang, Qiang Li, Guoming Wu
BACKGROUND: Anlotinib (AL3818) is a novel multitarget tyrosine kinase inhibitor, inhibiting tumour angiogenesis and proliferative signalling. The objective of this study was to assess the safety and efficacy of third-line anlotinib for patients with refractory advanced non-small-cell lung cancer (RA-NSCLC). METHODS: Eligible patients were randomised 1 : 1 to receive anlotinib (12 mg per day, per os; days 1-14; 21 days per cycle) or a placebo. The primary end point was progression-free survival (PFS)...
February 13, 2018: British Journal of Cancer
https://www.readbyqxmd.com/read/29438372/a-phase-i-trial-of-the-%C3%AE-secretase-inhibitor-mk-0752-in-combination-with-gemcitabine-in-patients-with-pancreatic-ductal-adenocarcinoma
#18
Natalie Cook, Bristi Basu, Donna-Michelle Smith, Aarthi Gopinathan, Jeffry Evans, William P Steward, Daniel Palmer, David Propper, Balaji Venugopal, Mirela Hategan, D Alan Anthoney, Lisa V Hampson, Michael Nebozhyn, David Tuveson, Hayley Farmer-Hall, Helen Turner, Robert McLeod, Sarah Halford, Duncan Jodrell
BACKGROUND: The Notch pathway is frequently activated in cancer. Pathway inhibition by γ-secretase inhibitors has been shown to be effective in pre-clinical models of pancreatic cancer, in combination with gemcitabine. METHODS: A multi-centre, non-randomised Bayesian adaptive design study of MK-0752, administered per os weekly, in combination with gemcitabine administered intravenously on days 1, 8 and 15 (28 day cycle) at 800 or 1000 mg m -2 , was performed to determine the safety of combination treatment and the recommended phase 2 dose (RP2D)...
February 13, 2018: British Journal of Cancer
https://www.readbyqxmd.com/read/29438371/a-new-panel-of-pancreatic-cancer-biomarkers-discovered-using-a-mass-spectrometry-based-pipeline
#19
Xiaohui Liu, Weimin Zheng, Wansheng Wang, Huali Shen, Linxiao Liu, Wenhui Lou, Xiaolin Wang, Pengyuan Yang
This corrects the article DOI: 10.1038/bjc.2017.365.
February 13, 2018: British Journal of Cancer
https://www.readbyqxmd.com/read/29438370/health-related-quality-of-life-impact-of-cobimetinib-in-combination-with-vemurafenib-in-patients-with-advanced-or-metastatic-braf-v600-mutation-positive-melanoma
#20
Brigitte Dréno, Paolo A Ascierto, Victoria Atkinson, Gabriella Liszkay, Michele Maio, Mario Mandalà, Lev Demidov, Daniil Stroyakovskiy, Luc Thomas, Luis de la Cruz-Merino, Caroline Dutriaux, Claus Garbe, Karen Bartley, Thomas Karagiannis, Ilsung Chang, Isabelle Rooney, Daniel O Koralek, James Larkin, Grant A McArthur, Antoni Ribas
BACKGROUND: In the coBRIM study, cobimetinib plus vemurafenib (C+V) significantly improved survival outcomes vs placebo and vemurafenib (P+V) in patients with advanced/metastatic BRAF V600 -mutated melanoma. An analysis of health-related quality of life (HRQOL) from coBRIM is reported. METHODS: Patients completing the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 (QLQ-C30) at baseline and ⩾1 time point thereafter constituted the analysis population...
February 13, 2018: British Journal of Cancer
journal
journal
23366
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"