Faisal Amin, Nadia Mukhtar, Muzaffar Ali, Rehman Shehzad, Saima Ayub, Asim Aslam, Ali Ahmed Sheikh, Bakht Sultan, Muhammad Danish Mahmood, Muhammad Furqan Shahid, Saima Yaqub, Hassaan Bin Aslam, Muhammad Waqar Aziz, Tahir Yaqub
The aim of the current study was to map the genetic diversity in the haemagglutinin (HA) glycoprotein of influenza A viruses (IAVs) of the H9N2 subtype. Twenty-five H9N2 IAVs were isolated from broiler chickens from March to July 2019. The HA gene was amplified, and phylogenetic analysis was performed to determine the evolutionary relationship. Important antigenic amino acid residues of HA attributed to immune escape and zoonotic potential were compared among H9N2 IAVs. Phylogenetic analysis revealed that sublineage B2 under the G1 lineage in Pakistan was found to be diversified, and newly sequenced H9N2 isolates were nested into two clades (A and B)...
March 2024: Avian Diseases