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Acta Cardiologica

Frank Cools, Bart Wollaert, Geert Vervoort, Stefan Verstraete, Joeri Voet, Kurt Hermans, Alex Heyse, Axel De Wolf, Geert Hollanders, Tim Boussy, Wim Anné, Jan Vercammen, Dirk Faes, Michel Beutels, Georges Mairesse, Philippe Purnode, Ivan Blankoff, Peter Vandergoten, Luc Capiau, Jagan Allu, Jean-Pierre Bassand, Gloria Kayani
BACKGROUND: AF, anticoagulation, NOACs, changing patterns of prescription. METHODS: We describe baseline data and treatment patterns of patients recruited in Belgium in the Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF). Recruitment began when novel oral anticoagulants (NOACs) were introduced and provides a unique picture of changing treatment patterns over time. 1713 patients with a new (≤6 weeks duration) diagnosis of non-valvular atrial fibrillation (NVAF) and at least one investigator-defined stroke risk factor were recruited between May 2012 and August 2016, and will be prospectively followed for at least 2 years...
October 27, 2018: Acta Cardiologica
Laurent Pireau, Benoit Doyen
No abstract text is available yet for this article.
October 25, 2018: Acta Cardiologica
Jun-Jiang Chen, Wen-Ming Ma, Jing-Liang Yuan, Lian-Qun Cui
AIM: Particulate matter 2.5 (PM2.5) exposure is high risk to cardiovascular diseases. We investigated the influence of PM2.5 exposure on pulmonary arterial hypertension (PAH) murine model induced by left ventricular (LV) failure. METHODS: Thirty 10 weeks old C57BL/6 mice were randomised to four groups: sham group, sham + PM2.5 group, TAC group, and TAC + PM2.5 group. Eight weeks post TAC surgery, right ventricular (RV) and lung remodelling (Sirius Red staining and WGA Staining), heart and lung function (EF and RVSBP), and fibrotic genes (TGF-ti mRNA expression and collagen III protein level in lung tissue were measured...
October 22, 2018: Acta Cardiologica
Jin Li, Dominic Wyrsch, Dik Heg, Michael Stoller, Thomas Zanchin, Tilman Perrin, Stephan Windecker, Lorenz Räber, Laurent Roten
BACKGROUND: The outcome of patients undergoing percutaneous coronary interventions (PCIs) varies considerably. Several ECG parameters have recently emerged (PQ interval, P-wave, T-peak-to-T-end interval, T-wave, T/R ratio, J-wave) beyond traditional markers (rhythm, QRS, Q-wave, QT interval, ST segment) and were attributed important prognostic value in the setting of coronary artery disease. The present study integrated for the first time these ECG parameters altogether with the aim to determine their role in predicting patients' outcome after a PCI...
October 17, 2018: Acta Cardiologica
(no author information available yet)
No abstract text is available yet for this article.
October 17, 2018: Acta Cardiologica
Laurent Davin, Patrick Marechal, Patrizio Lancellotti, Christophe Martinez, Luc Pierard, Regis Radermecker
The effects of angiotensin converting enzyme (ACE) inhibitors result from the inhibition of the ACE (kininase II) to ultimately influence both the renin-angiotensin system and the degradation of the bradykinin (BK) metabolism. ACE inhibitors block the degradation of BK and substance P by ACE. In addition, an active metabolite of BK (Des-Arg9-BK) is catalysed by kininase I and its degradation is controlled in part by the conversion enzyme. These molecules have been associated with increased plasma extravasation associated with ACE inhibitors...
October 17, 2018: Acta Cardiologica
Serkan Ünlü, Serdar Gökhan Nurkoç, Burak Sezenöz, Mehmet Cingirt, Özlem Gülbahar, Adnan Abacı
BACKGROUND: High-sensitive cardiac troponin (hsTn) levels can be elevated due to non-pathological events such as strenuous exercise. However, the effect of statins on circulating hsTnT levels with moderate exercise is uncertain. Therefore, we evaluated the impact of statins on hsTnT level with moderate exercise. METHODS: We enrolled a total of 56 patients: 26 statin users and 30 non-users. All patients were shown to have no coronary artery disease before participating in the study...
October 17, 2018: Acta Cardiologica
Jeff C Huffman, Diana M Smith, Nasrien E Ibrahim, Laura Duque, Judith T Moskowitz, Christopher M Celano
No abstract text is available yet for this article.
October 17, 2018: Acta Cardiologica
Wasawat Vutthikraivit, Pattara Rattanawong, Jakrin Kewcharoen, Chanavuth Kanitsoraphan, Pavida Pachariyanon, Sakolwan Suchartlikitwong, Saranapoom Klomjit, Pakpoom Tantrachoti
BACKGROUND: Recent studies suggested that chronic total occlusion of the coronary artery increased risk of ventricular arrhythmia (VA) and all-cause mortality in ischaemic cardiomyopathy (ICM) patient who underwent implantable cardiac defibrillator (ICD) implantation. We aim to demonstrate an association between a presence of CTO and poor cardiovascular outcome in ICD implanted ICM patients. OBJECTIVE: To examine the association between the presence of CTO and all-cause mortality in ICM with ICD implantation Methods: We comprehensively searched the databases of MEDLINE and EMBASE from inception to February 2018...
October 17, 2018: Acta Cardiologica
Napatt Kanjanahattakij, Pattara Rattanawong, Parasuram Krishnamoorthy, Natee Sirinvaravong, Pakawat Chongsathidkiet, Kamolyut Lapumnuaypol, Jon C George, Christian Witzke, Vincent M Figueredo
OBJECTIVE: This study was done to determine the relationship between pre-procedural anaemia and mortality post transcatheter aortic valve replacement (TAVR). INTRODUCTION: TAVR is now a treatment option for patients with severe aortic stenosis (AS) with high surgical risk. Anaemia is a common comorbidity in the TAVR population. Small studies have suggested that anaemia is associated with worse short-term and long-term mortality in patients who underwent TAVR. However, there are no meta-analyses to further assess this association...
October 17, 2018: Acta Cardiologica
Michael Efremidis, Konstantinos P Letsas, Stamatis Georgopoulos, Nikolaos Karamichalakis, Konstantinos Vlachos, Louiza Lioni, George Bazoukis, Athanasios Saplaouras, Antigoni Sakellaropoulou, Angelos Michael Kolokathis, Aikaterini Rokiza, Aikaterini Anagnostou, Kosmas Valkanas, Antonios Sideris
BACKGROUND: Data regarding long-term outcomes of atrial fibrillation (AF) catheter ablation are limited. This study evaluated the safety, long-term efficacy and predictors of recurrence after a single left atrial ablation procedure in patients with paroxysmal (PAF) and non-paroxysmal AF (NPAF). METHODS: Data from 520 patients (354 males, mean age 57.08 ± 11.33 years) with PAF (n = 356, 68.5%) or NPAF (n = 164, 31.5%) who underwent a single radiofrequency ablation procedure were analysed...
October 10, 2018: Acta Cardiologica
Marie Smets, Miek Smeets, Steve Van den Bulck, Stefan Janssens, Bert Aertgeerts, Bert Vaes
BACKGROUND: Quality indicators (QIs) are used to measure and evaluate quality of care. However, QIs to evaluate care for HF patients in general practice in Belgium are lacking. Therefore, this study aimed to determine which QIs, rooted in the electronic health record (EHR), are useful to monitor quality of care for patients with HF in general practice. METHODS: The RAND/UCLA appropriateness method (a modified Delphi method) was used to define these assigned QIs...
September 27, 2018: Acta Cardiologica
Tim Balthazar, Christiaan Scheurwegs, Marguerite Stas, Werner Budts
No abstract text is available yet for this article.
September 27, 2018: Acta Cardiologica
Suncica Stankovic, Slobodan Obradovic, Boris Dzudovic, Nemanja Djenic, Radoslav Romanovic, Zoran Jovic, Marijan Spasic, Obrad Djuric, Dragana Malovic, Milena Stavric, Vesna Subota
BACKGROUND: Activity of protein C has important role in the development of early necrosis and no-reflow phenomenon in patients with ST-segment elevation myocardial infarction (STEMI) after successful primary percutaneous coronary intervention (pPCI). METHODS: We examined association between plasma activity of protein C, antithrombin, coagulation factors II, VII, VIII and fibrinogen to early formation of new Q-waves (myocardial necrosis) before pPCI and early ST-segment resolution (microcirculatory reperfusion) after pPCI in patients with acute STEMI...
September 11, 2018: Acta Cardiologica
Jakub Rychlik, Ivan Hornacek, Miloslav Tejc, Erik Petrikovits, Zdenek Klimsa
OBJECTIVES: The aim of this study was to analyse the consequence of radial or femoral access during coronary interventions to radiation dose, fluorography time and a number of pseudoaneurysms following each type of intervention. BACKGROUND: According to the results of many recent studies (RIVAL, RIFLE-STEACS, STEMI RADIAL), current guidelines favour radial over femoral access during coronary intervention for safety, especially in cases of acute coronary syndromes...
September 7, 2018: Acta Cardiologica
Yavuz Karabağ, Tufan Çınar, Metin Çağdaş, İbrahim Rencüzoğulları, Veysel Ozan Tanık
BACKGROUND: The recent reclassification of heart failure (HF) patients in the 2016 European Society of Cardiology HF guidelines according to the left ventricular ejection fraction (LVEF) has created a 'grey area' consisting of midrange ejection fraction (mrEF) HF patients with LVEFs of 40-49%. Additionally, there is limited data regarding the in-hospital and long-term prognoses of patients with an mrEF after an ST-elevation myocardial infarction (STEMI). Therefore, we aimed to evaluate the baseline characteristics, in-hospital and long-term mortalities, clinical events in mrEF, preserved ejection fraction (pEF), and reduced ejection fraction (rEF) patients during their hospital stays in a cohort of consecutive STEMI patients who underwent primary percutaneous coronary intervention (PCI)...
August 23, 2018: Acta Cardiologica
N Brasier, S Engelter, T Kolbitsch, A Tabord, J Knobeloch, M Kühne, D Conen, C Traenka, T Kreutzberger, G Völlmin, J Eckstein
BACKGROUND: Atrial fibrillation (AF) is related to an increased stroke risk. At present, differentiation between patients with paroxysmal AF (pAF) and without is only possible during AF episodes and not during sinus rhythm. If AF could be diagnosed more quickly and reliably, anticoagulation therapy may be administered and prevent from cardioembolic strokes. The DETECT AF trial evaluated the hypothesis that propagation of electric activities in patients with pAF differs from propagation in healthy atria and that this can be detected with a three-dimensional electrocardiogram in patients during sinus rhythm...
August 19, 2018: Acta Cardiologica
Pierre-Vladimir Ennezat, Patrick Bruneval, Olivier Stephanov, Olivier Chavanon
No abstract text is available yet for this article.
August 2018: Acta Cardiologica
Maarten Vanhaverbeke, Keir McCutcheon, Christophe Dubois, Johan Bennett
No abstract text is available yet for this article.
August 2018: Acta Cardiologica
Muthiah Subramanian, Mukund A Prabhu, Selva Saravanan, Rajesh Thachathodiyl
BACKGROUND: The utility of biomarkers for prognostication of long term outcomes in patients with anaemia and heart failure(HF) is not well defined. The objective of this study was to assess the ability of a novel biomarker, bio-width index (BWI),to improve risk stratification in patients with anaemia and acutely decompensated heart failure(ADHF), in comparison to conventional markers, B-type natriuretic peptide(BNP) and red- cell distribution width(RDW). METHODS: Data from 1569 consecutive patients with ADHF treated at a multidisciplinary HF unit was analysed in this study...
August 2018: Acta Cardiologica
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