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Anaesthesia

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https://www.readbyqxmd.com/read/30427065/assessment-of-haemoglobin-measurement-by-several-methods-blood-gas-analyser-capillary-and-venous-hemocue-%C3%A2-non-invasive-spectrophotometry-and-laboratory-assay-in-term-and-preterm-infants
#1
E Wittenmeier, L Lesmeister, N Pirlich, F Dette, I Schmidtmann, E Mildenberger
A laboratory haematology analyser is the gold standard for measuring haemoglobin concentration but has disadvantages, especially in neonates. This study compared alternative blood-sparing and non-invasive methods of haemoglobin concentration measurement with the gold standard. Haemoglobin concentrations were measured using a laboratory haematology analyser (reference method), blood gas analyser, HemoCue® using venous and capillary blood samples and a newly developed non-invasive sensor for neonates < 3 kg...
November 14, 2018: Anaesthesia
https://www.readbyqxmd.com/read/30427059/identifying-the-optimal-regional-predictor-of-right-ventricular-global-function-a-high-resolution-three-dimensional-cardiac-magnetic-resonance-study
#2
T J W Dawes, A de Marvao, W Shi, D Rueckert, S A Cook, D P O'Regan
Right ventricular (RV) function has prognostic value in acute, chronic and peri-operative disease, although the complex RV contractile pattern makes rapid assessment difficult. Several two-dimensional (2D) regional measures estimate RV function, however the optimal measure is not known. High-resolution three-dimensional (3D) cardiac magnetic resonance cine imaging was acquired in 300 healthy volunteers and a computational model of RV motion created. Points where regional function was significantly associated with global function were identified and a 2D, optimised single-point marker (SPM-O) of global function developed...
November 14, 2018: Anaesthesia
https://www.readbyqxmd.com/read/30390299/taking-on-tiva-why-we-need-guidelines-on-total-intravenous-anaesthesia
#3
EDITORIAL
M G Irwin, G T C Wong
No abstract text is available yet for this article.
November 2, 2018: Anaesthesia
https://www.readbyqxmd.com/read/30383307/genomic-consequences-of-sleep-restriction-the-devil-is-in-the-details
#4
EDITORIAL
P M Fuller, M Eikermann
No abstract text is available yet for this article.
November 1, 2018: Anaesthesia
https://www.readbyqxmd.com/read/30383296/parental-perception-on-the-effects-of-early-exposure-to-anaesthesia-on-neurodevelopment
#5
J H Koh, P Daniel, C L Bong
Several studies have investigated the effects of general anaesthesia on neurodevelopment in children, with conflicting results. The potential for early general anaesthesia exposure to impact neurodevelopment in children may cause significant concern for parents. Administering a questionnaire in 200 parents, we aimed to explore their knowledge, concerns and perceptions, and determine factors which influence parents' willingness for their children to participate in relevant research studies. A significant proportion of parents (40%) were concerned that general anaesthesia may affect their child's neurodevelopment...
November 1, 2018: Anaesthesia
https://www.readbyqxmd.com/read/30383289/the-analgesic-effects-of-intrathecal-morphine-in-comparison-with-ultrasound-guided-transversus-abdominis-plane-block-after-caesarean-section-a-randomised-controlled-trial-at-a-ugandan-regional-referral-hospital
#6
A Kwikiriza, J K Kiwanuka, P G Firth, M A Hoeft, V E Modest, S S Ttendo
Both transversus abdominis plane block and intrathecal morphine may produce prolonged postoperative analgesia, but the respective clinical outcomes of these anaesthetic techniques in resource-limited settings are not well described. We randomly assigned patients undergoing caesarean section to receive a hyperbaric bupivacaine (10 mg) spinal anaesthetic followed by an ultrasound-guided transversus abdominis plane block, or a hyperbaric bupivacaine (10 mg) spinal anaesthetic with 100 mcg intrathecal morphine, followed by a postoperative sham block...
November 1, 2018: Anaesthesia
https://www.readbyqxmd.com/read/30378102/guidelines-for-the-safe-practice-of-total-intravenous-anaesthesia-tiva-joint-guidelines-from-the-association-of-anaesthetists-and-the-society-for-intravenous-anaesthesia
#7
LETTER
A F Nimmo, A R Absalom, O Bagshaw, A Biswas, T M Cook, A Costello, S Grimes, D Mulvey, S Shinde, T Whitehouse, M D Wiles
Guidelines are presented for safe practice in the use of intravenous drug infusions for general anaesthesia. When maintenance of general anaesthesia is by intravenous infusion, this is referred to as total intravenous anaesthesia. Although total intravenous anaesthesia has advantages for some patients, the commonest technique used for maintenance of anaesthesia in the UK and Ireland remains the administration of an inhaled volatile anaesthetic. However, the use of an inhalational technique is sometimes not possible, and in some situations, inhalational anaesthesia is contraindicated...
October 31, 2018: Anaesthesia
https://www.readbyqxmd.com/read/30375644/medication-handling-towards-a-practical-human-centred-approach
#8
EDITORIAL
S D Marshall, N Chrimes
No abstract text is available yet for this article.
October 30, 2018: Anaesthesia
https://www.readbyqxmd.com/read/30367693/why-does-retraction-take-so-much-longer-than-publication
#9
EDITORIAL
J A Loadsman
No abstract text is available yet for this article.
October 27, 2018: Anaesthesia
https://www.readbyqxmd.com/read/30367689/the-effect-of-dexmedetomidine-on-delirium-and-agitation-in-patients-in-intensive-care-systematic-review-and-meta-analysis-with-trial-sequential-analysis
#10
REVIEW
K T Ng, C J Shubash, J S Chong
Delirium is common in intensive care patients. Dexmedetomidine is increasingly used for sedation in this setting, but its effect on delirium remains unclear. The primary aim of this review was to examine whether dexmedetomidine reduces the incidence of delirium and agitation in intensive care patients. We sought randomised clinical trials in MEDLINE, EMBASE, PubMed and CENTRAL from their inception until June 2018. Observational studies, case reports, case series and non-systematic reviews were excluded. Twenty-five trials including 3240 patients were eligible for inclusion in the data synthesis...
October 27, 2018: Anaesthesia
https://www.readbyqxmd.com/read/30367688/the-impact-of-emergency-department-patient-controlled-analgesia-pca-on-the-incidence-of-chronic-pain-following-trauma-and-non-traumatic-abdominal-pain
#11
M Rockett, S Creanor, R Squire, A Barton, J Benger, L Cocking, P Ewings, V Eyre, J E Smith
The effect of patient-controlled analgesia during the emergency phase of care on the prevalence of persistent pain is unkown. We studied individuals with traumatic injuries or abdominal pain 6 months after hospital admission via the emergency department using an opportunistic observational study design. This was conducted using postal questionnaires that were sent to participants recruited to the multi-centre pain solutions in the emergency setting study. Patients with prior chronic pain states or opioid use were not studied...
October 27, 2018: Anaesthesia
https://www.readbyqxmd.com/read/30367683/electroencephalographic-eeg-density-spectral-array-monitoring-in-children-during-sevoflurane-anaesthesia-a-prospective-observational-study
#12
I J de Heer, S J M Bouman, F Weber
Electroencephalographic density spectral array monitoring has been developed to facilitate the interpretation of unprocessed electroencephalogram signals. The primary aim of this prospective observational study, performed in a tertiary children's hospital, was to identify the clinical applicability and validity of density spectral array monitoring in infants and children during sevoflurane anaesthesia. We included 104 children, aged < 6 years, undergoing elective surgery during sevoflurane anaesthesia. We investigated the correlation between non-steady state end-tidal sevoflurane and the expression of the four electroencephalogram frequency bands β, α, θ and δ, representing density spectral array...
October 27, 2018: Anaesthesia
https://www.readbyqxmd.com/read/30341946/the-global-capnography-gap-a-call-to-action
#13
EDITORIAL
M S Lipnick, P Mavoungou, A W Gelb
No abstract text is available yet for this article.
October 20, 2018: Anaesthesia
https://www.readbyqxmd.com/read/30339281/reducing-the-risk-of-neurological-complications-after-peripheral-nerve-block-what-is-the-role-of-pressure-monitoring
#14
EDITORIAL
M J Barrington, P Lirk
No abstract text is available yet for this article.
October 19, 2018: Anaesthesia
https://www.readbyqxmd.com/read/30338522/doctor-why-are-you-driving-a-wedge-between-us-calculating-sample-size-in-multiple-testing-and-the-need-for-geisser-greenhouse-correction
#15
S W Choi, G T C Wong
No abstract text is available yet for this article.
October 18, 2018: Anaesthesia
https://www.readbyqxmd.com/read/30338515/a-prospective-observational-study-of-cerebrovascular-autoregulation-and-its-association-with-delirium-following-cardiac-surgery
#16
B Chan, A Aneman
This aim of this prospective observational cohort study was to evaluate any association between postoperatively impaired cerebrovascular autoregulation and the onset of delirium following cardiac surgery. Previous studies have shown that impaired intra-operative cerebrovascular autoregulation during cardiopulmonary bypass is associated with delirium. However, postoperative changes in cerebrovascular autoregulation and its association with delirium have not been investigated. One-hundred and eight consecutive adult cardiac surgical patients without baseline cognitive dysfunction or aphasia were included in the study...
October 18, 2018: Anaesthesia
https://www.readbyqxmd.com/read/30329150/from-evidence-based-on-practice-to-evidence-based-practice-time-for-a-difficult-airway-management-research-strategy
#17
EDITORIAL
I Ahmad, K El-Boghdadly
No abstract text is available yet for this article.
October 17, 2018: Anaesthesia
https://www.readbyqxmd.com/read/30325495/defining-peri-operative-anaemia-in-pregnant-women-challenging-the-status-quo
#18
REVIEW
M T Ferguson, A T Dennis
Peri-operative anaemia is a significant risk factor for morbidity and mortality. Anaemia during pregnancy is associated with adverse maternal and neonatal outcomes, and postpartum haemorrhage remains a leading cause of maternal mortality worldwide. Caesarean section is an operation incurring moderate risk of bleeding, and rates are rising globally. Recent international consensus guidelines recommend targeting a pre-operative haemoglobin > 130 g.l-1 for all patients having surgery with moderate-to-high risk of bleeding, regardless of sex...
October 16, 2018: Anaesthesia
https://www.readbyqxmd.com/read/30315725/implications-of-deranged-activated-partial-thromboplastin-time-for-anaesthesia-and-surgery
#19
REVIEW
E Loizou, D J Mayhew, V Martlew, B V S Murthy
Bleeding during and after surgery ranges from trivial to fatal. Bleeding is in part determined by the patient's coagulation status. The UK National Institute for Health and Care Excellence recommends a pre-operative clotting test for patients with a history of abnormal bleeding. Anaesthetists are familiar with the prothrombin time assay, used to monitor warfarin effect, but anaesthetists may be less familiar with the activated partial thromboplastin time (APTT), which tests the function of the 'intrinsic' clotting pathway...
October 13, 2018: Anaesthesia
https://www.readbyqxmd.com/read/30315708/body-temperature-cutaneous-heat-loss-and-skin-blood-flow-during-epidural-anaesthesia-for-emergency-caesarean-section
#20
C J Mullington, D A Low, P H Strutton, S Malhotra
It is not clear how converting epidural analgesia for labour to epidural anaesthesia for emergency caesarean section affects either cutaneous vasomotor tone or mean body temperature. We hypothesised that topping up a labour epidural blocks active cutaneous vasodilation (cutaneous heat loss and skin blood flow decrease), and that as a result mean body temperature increases. Twenty women in established labour had body temperature, cutaneous heat loss and skin blood flow recorded before and after epidural top-up for emergency caesarean section...
October 13, 2018: Anaesthesia
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