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American Journal of the Medical Sciences

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https://www.readbyqxmd.com/read/30413246/disseminated-tuberculosis-in-the-differential-diagnosis-of-hemophagocytic-syndrome-author-response
#1
LETTER
Mohammed Ruzieh, Fadi Safi, Joan Duggan
No abstract text is available yet for this article.
October 3, 2018: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/30389098/errata
#2
(no author information available yet)
No abstract text is available yet for this article.
September 29, 2018: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/30415760/the-archtypes-of-medicine-a-job-description-for-the-21st-century
#3
EDITORIAL
Salvatore Mangione, Jennifer Fisher Wilson, Steven K Herrine
Medicine is facing an identity crisis, one that might find resolution by revisiting a past rich in multifaceted individuals who transcended the strict definition of 'doctor', excelled in other fields of human endeavor, and showed us different ways of being physicians. This paper reviews 12 archetypes that have been part of the profession since its inception, but that, as of late, might have been forgotten. Our goal is to elicit discussion and introspection, with the premise that being a physician ought to be something larger than being a mere technician...
September 27, 2018: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/30392586/a-brief-meta-analysis-of-oxygen-therapy-for-normoxemic-patients-with-acute-coronary-syndrome
#4
LETTER
Rahman Shah, Sarah M Wilson, Mallie M Dennis, Babar Khan, Samuel B Latham
No abstract text is available yet for this article.
September 25, 2018: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/30342716/low-frequency-of-staphylococcus-aureus-in-lower-extremity-skin-and-soft-tissue-infections
#5
Farah Tanveer, Ashish Bhargava, Kathleen Riederer, Leonard B Johnson, Riad Khatib
BACKGROUND: Staphylococcus aureus is often implicated in skin/soft tissue infections (SSTI). However, SSTI at sites of pressure necrosis and peripheral vascular disease (PVD) are often polymicrobial. The frequency of S aureus in these infections is uncertain. METHODS: We retrospectively reviewed culture results from adults (January 1, 2015-March 31, 2017), evaluated their records and selected SSTI in lower extremities. The patient demographics, comorbidities, characteristics and culture results were recorded...
September 21, 2018: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/30342717/metformin-associated-with-improved-outcomes-in-diabetic-patients-with-laryngeal-and-oropharyngeal-carcinoma
#6
LETTER
Amie Ogunsakin, Jordan Infield, Jeffery Zuber, Solomon S Solomon
No abstract text is available yet for this article.
September 13, 2018: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/30342719/clinical-efficacy-of-serum-derived-bovine-immunoglobulin-in-patients-with-refractory-inflammatory-bowel-disease
#7
Hammad Liaquat, Munish Ashat, Abigail Stocker, Lindsay McElmurray, Karen Beatty, Thomas L Abell, Gerald Dryden
BACKGROUND: Inflammatory bowel disease (IBD) can have autoimmunity and/or intestinal barrier dysfunction as part of pathophysiology and may be refractory to all available treatment options. Serum-derived bovine immunoglobulin (SBI) binds microbial components with postulated downstream effects of normalized gut immune and barrier function, which may be useful for managing IBD. The purpose of our study was to evaluate the effectiveness of SBI in the management of refractory IBD, particularly symptoms of chronic diarrhea and loose stools...
September 5, 2018: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/30342718/galectin-3-a-novel-biomarker-predicts-sudden-cardiac-death-in-hypertrophic-cardiomyopathy
#8
Samim Emet, Mubariz Dadashov, Mehmet Rasih Sonsoz, Mustafa Ozan Cakir, Mustafa Yilmaz, Ali Elitok, Ahmet Kaya Bilge, Fehmi Mercanoglu, Aytac Oncul, Kamil Adalet, Imran Onur
BACKGROUND: Hypertrophic cardiomyopathy is a primary cardiac disease characterized by left ventricular hypertrophy, myocyte hypertrophy and irregularities and interstitial fibrosis in the absence of any cardiac or systemic diseases and may lead to sudden cardiac death (SCD). Galectin-3 is a β-galactoside-binding lectin that has been associated with cardiac fibrosis and inflammation. In this study, we aimed to investigate the relationship between serum galectin-3 levels and the criteria for 5-year sudden death risk, recently defined in the European Society of Cardiology guidelines (2014), in patients with hypertrophic cardiomyopathy...
August 29, 2018: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/30392587/igg4-related-pleuritis-without-tuberculous-pleurisy
#9
LETTER
Toshiyuki Kita
No abstract text is available yet for this article.
August 28, 2018: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/30314832/ewing-s-sarcoma-and-or-peripheral-primitive-neuroectodermal-tumorsin-bronchus
#10
REVIEW
Jun Chen, Tao Yuan, Xiao Liu, Bei Hua, Chenfeng Dong, Yawu Liu, Guanmin Quan
Ewing sarcoma/peripheral primitive neuroectodermal tumors (ES/pPNET), a member of the Ewing sarcoma family of tumors, is a malignant soft tissue tumor with small undifferentiated neuroectodermal cells. Primary trachea-bronchial ES/pPNET is very rare. The most common pulmonary ES is due to a metastasis. We describe a case of ES/pPNET which originated in the left basal trunk bronchus. The patient was a 30-year-old male, presenting with irritable cough and fever for 10 days. A tumor of 60 mm in diameter was found in the left basal trunk bronchus, extending to the left lower lobe...
August 22, 2018: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/30278878/a-patient-centered-approach-to-care-and-research-in-chronic-disease
#11
EDITORIAL
Jeffrey J Swigris
No abstract text is available yet for this article.
August 21, 2018: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/30384955/emerging-role-for-exosomes-in-the-progress-of-stem-cell-research
#12
REVIEW
Kai-Ming Yuan, Pei-Hua Zhang, Shan-Shan Qi, Qiao-Zhen Zhu, Ping Li
Exosomes are small secretory vesicles that are involved in intercellular communication. Exosomes are secreted by many types of cells and exert important functions in plasma-membrane exchange as well as the transport of bioactive substances, such as proteins, messenger ribonucleic acids (mRNAs), micro ribonucleic acids (miRNAs) and organelles. Exosomes may regulate physiological processes by altering gene regulatory networks or epigenetic recombination. Recent studies have shown that exosomes secreted by stem cells can effectively transport proteins, mRNAs and miRNAs and play important roles in the regulation of tissue regeneration...
November 2018: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/30384954/urgent-start-intermittent-peritoneal-dialysis-leads-to-reduction-of-catheter-related-infection-and-increased-peritoneal-dialysis-penetration
#13
Malini Shanmuganathan, Bak Leong Goh, Christopher T S Lim
BACKGROUND: Noncuffed catheters (NCC) are often used for incident hemodialysis (HD) patients without a functional vascular access. This, unfortunately results in frequent catheter-related complications such as infection, malfunction, vessel stenosis, and obstruction, leading to loss of permanent central venous access with superior vena cava obstruction. It is important to preserve central vein patency by reducing the number of internal jugular catheter insertions for incident HD patients with a functional vascular access...
November 2018: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/30384953/risk-factors-for-low-pharmacy-refill-adherence-among-older-hypertensive-men-and-women-by-race
#14
LaKeisha G Williams, Erin Peacock, Cara Joyce, Lydia A Bazzano, Daniel Sarpong, Paul K Whelton, Elizabeth W Holt, Richard Re, Edward Frohlich, Jiang He, Paul Muntner, Marie Krousel-Wood
BACKGROUND: Sex-race stratification may lead to identification of risk factors for low antihypertensive medication adherence that are not apparent when assessing risk factors in women and men without race stratification. We examined risk factors associated with low pharmacy refill adherence across sex-race subgroups (white women, black women, white men, black men) within the Cohort Study of Medication Adherence among Older Adults (n = 2,122). METHODS: Pharmacy refill adherence was calculated as proportion of days covered using all antihypertensive prescriptions filled in the year prior to a baseline risk factor survey...
November 2018: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/30384952/the-use-of-microbiome-restoration-therapeutics-to-eliminate-intestinal-colonization-with-multidrug-resistant-organisms
#15
Srinivasa Nithin Gopalsamy, Michael H Woodworth, Tiffany Wang, Cynthia T Carpentieri, Nirja Mehta, Rachel J Friedman-Moraco, Aneesh K Mehta, Christian P Larsen, Colleen S Kraft
Antibiotic resistance (AR) has been described by the World Health Organization as an increasingly serious threat to global public health. Many mechanisms of AR have become widespread due to global selective pressures such as widespread antibiotic use. The intestinal tract is an important reservoir for many multidrug-resistant organisms (MDROs), and next-generation sequencing has expanded understanding of the resistome, defined as the comprehensive sum of genetic determinants of AR. Intestinal decolonization has been explored as a strategy to eradicate MDROs with selective digestive tract decontamination and probiotics being notable examples with mixed results...
November 2018: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/30384951/current-evidence-in-delivery-and-therapeutic-uses-of-fecal-microbiota-transplantation-in-human-diseases-clostridium-difficile-disease-and-beyond
#16
Joshua Stripling, Martin Rodriguez
The use of fecal microbiota transplantation (FMT) was first described in China in the 4th century by Ge Hong when "yellow soup," a fecal slurry, was administered for the treatment of severe food poisoning and diarrhea, a practice that continued for centuries. Bedouin groups also consumed stools of their camels as a remedy for dysentery. FMT was also applied in veterinary medicine in Europe in the 16th century. Additional therapeutic use of human excretions was described in Europe in the 18th and 19th century and in World War II, when gut bacteria were administered to German soldiers suffering from dysentery in the North African campaign...
November 2018: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/30384950/development-of-the-pediatric-gut-microbiome-impact-on-health-and-disease
#17
Faith D Ihekweazu, James Versalovic
The intestinal microbiota are important in human growth and development. Microbial composition may yield insights into the temporal development of microbial communities and vulnerabilities to disorders of microbial ecology such as recurrent Clostridium difficile infection. Discoveries of key microbiome features of carbohydrate and amino acid metabolism are lending new insights into possible therapies or preventative strategies for inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS). In this review, we summarize the current understanding of the development of the pediatric gastrointestinal microbiome, the influence of the microbiome on the developing brain through the gut-brain axis, and the impact of dysbiosis on disease development...
November 2018: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/30384949/coronary-artery-disease-in-systemic-lupus-erythematosus
#18
EDITORIAL
Jan Nilsson
No abstract text is available yet for this article.
November 2018: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/30384948/study-of-the-microbiome-has-reached-prime-time
#19
EDITORIAL
C Mel Wilcox
No abstract text is available yet for this article.
November 2018: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/30241668/risk-of-coronary-artery-disease-in-patients-with-systemic-lupus-erythematosus-a-systematic-review-and-meta-analysis
#20
Huimin Li, Qian Tong, Lirong Guo, Shui Yu, Yuewei Li, Qinqin Cao, Jinwei Li, Feng Li
BACKGROUND: The association between chronic inflammation and the accelerated development of atherosclerosis is well recognized. However, it remains controversial as to whether the risk of coronary artery disease (CAD) is elevated in patients with systemic lupus erythematosus (SLE). The objective of this meta-analysis was to obtain a better estimate of the risk of CAD in patients with SLE. METHODS: An English-restricted literature review was conducted according to PRISMA guidelines using key databases, surveying all articles published through October 31, 2017...
November 2018: American Journal of the Medical Sciences
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