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American Journal of the Medical Sciences

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https://www.readbyqxmd.com/read/30006195/prevalence-and-incidence-of-immune-thrombocytopenia-in-patients-with-prostate-cancer
#1
LETTER
Namratha Vontela, Csaba Kovesdy, Zafar Latif, Robert Lane, Alva Weir
No abstract text is available yet for this article.
May 5, 2018: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/30006196/congenital-absence-of-left-coronary-artery-accompanied-by-premature-ventricular-complexes
#2
LETTER
Hong-Feng Jin, Xiao-Wei Liu, Chang-Qing Du
No abstract text is available yet for this article.
May 1, 2018: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/29891049/a-huge-pancreas-tumor-with-periampullary-invasion
#3
LETTER
Yu-Jen Chen, Ching-Liang Lu
No abstract text is available yet for this article.
June 2018: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/29891048/not-all-gastric-masses-need-a-biopsy-a-cautionary-tale
#4
LETTER
Divyansh Bajaj, Roni Manyevitch, Gordon Gray Still
No abstract text is available yet for this article.
June 2018: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/29891047/about-a-suggestive-association-between-fanconi-anemia-and-laron-syndrome
#5
LETTER
I Castilla-Cortazar, G A Aguirre, J R De Ita
No abstract text is available yet for this article.
June 2018: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/29891046/in-reference-to-fanconi-anemia-and-laron-syndrome
#6
LETTER
Benilde García-de Teresa, Sara Frias
No abstract text is available yet for this article.
June 2018: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/29891045/biventricular-thrombi-in-a-patient-with-heart-failure-with-severely-reduced-ejection-fraction-and-heterozygous-prothrombin-20210g-a-and-homozygous-methylenetetrahydrofolate-reductase-677c-t-mutations
#7
REVIEW
Htoo Kyaw, Fatima Shaik, Won J Park, Deepika Misra
Thrombus in the heart is known to be one of the many sequelae of anterior wall myocardial infarction, atrial fibrillation and coagulation disorders. However, biventricular thrombi are relatively rarely found, even in conditions with a high possibility of thrombus formation. We report the case of a 75-year-old-woman with newly diagnosed systolic heart failure secondary to a nonischemic cardiomyopathy, who was found to have large biventricular thrombi. Further coagulopathy work-up revealed that she was heterozygous for the prothrombin 20210G/A and homozygous for the methylenetetrahydrofolate reductase (MTHFR) 677C/T mutations...
June 2018: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/29891044/the-first-reported-case-of-cytomegalovirus-gastritis-in-a-patient-with-end-stage-renal-disease
#8
REVIEW
Chi-Hao Liu, An-Hang Yang, Shuo-Ming Ou, Der-Cherng Tarng
Cytomegalovirus (CMV) infection is a common infectious complication in immunocompromised patients. The colon is the most common site of CMV infection in the gastrointestinal tract. Rarely, however, invasion of the upper gastrointestinal tract, such as the esophagus or stomach, has been reported. Herein, we describe the first reported case of CMV gastritis in a patient with end-stage renal disease and uremic symptoms (including nausea, vomiting, and poor appetite) who had begun hemodialysis therapy. This patient was not a transplant recipient and was not receiving immunosuppressant treatment...
June 2018: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/29891043/erythropoietin-enhances-bone-repair-effects-via-the-hypoxia-inducible-factor-signal-pathway-in-glucocorticoid-induced-osteonecrosis-of-the-femoral-head
#9
Donghai Li, Qinsheng Hu, Gang Tan, Xiaowei Xie, Zhouyuan Yang, Pengde Kang
BACKGROUND: This study aimed to determine whether erythropoietin could repair glucocorticoid-induced osteonecrosis of the femoral head after the systemic or local administration of recombinant human erythropoietin. MATERIALS AND METHODS: Gelatin microspheres were used to load recombinant human erythropoietin for local delivery. Forty-eight Wistar rats were included in the glucocorticoid-induced osteonecrosis of the femoral head model and randomly divided into the placebo, systemic erythropoietin and local erythropoietin groups...
June 2018: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/29891042/tetrahydroxy-stilbene-glucoside-alleviates-high-glucose-induced-mpc5-podocytes-injury-through-suppression-of-nlrp3-inflammasome
#10
Jinfeng Li, Bing Wang, Guangjie Zhou, Xiujuan Yan, Yuan Zhang
BACKGROUND: Tetrahydroxy stilbene glucoside (TSG) is an active ingredient of Heshouwu and is an antioxidant. The underlying mechanisms of the renoprotective effect of TSG in diabetic nephropathy have not been previously reported. In this study, we investigated the mechanisms of TSG in preventing podocytes injury in high glucose (HG) condition. METHODS: Cultured mouse podocytes (MPC5) were incubated in HG (30mmol/L) plus various concentration of TSG (0.1, 1 and 10μM) for 48 hours...
June 2018: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/29891041/spectrum-of-gastrointestinal-manifestations-in-joint-hypermobility-syndromes
#11
REVIEW
Gehan Botrus, Omar Baker, Erica Borrego, Kyari Sumayin Ngamdu, Mohamed Teleb, Jose L Gonzales Martinez, Gerardo Maldonado, Ahmed M Hussein, Richard McCallum
Joint hypermobility is a common, primarily benign finding in the general population. However, in a subset of individuals joint hypermobility causes a range of clinical problems mainly affecting the musculoskeletal system and, to a lesser extent, extra-articular disorders. Joint hypermobility often appears as a familial trait and is shared by several inherited connective tissue disorders, including the hypermobility subtype of Ehlers-Danlos syndrome (hEDS) and benign joint hypermobility syndrome (BJHS/JHS). Although joint hypermobility has primarily been thought of as a rheumatological disorder, increasing evidence shows significant associations between both hEDS and BJHS with specific extra-articular disorders...
June 2018: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/29891040/pegylated-interferon-%C3%AE-plus-ribavirin-therapy-improves-left-ventricular-diastolic-dysfunction-in-patients-with-chronic-hepatitis-c-attaining-sustained-virological-response
#12
Abdul-Quddus Mohammed, Ranshaka Auckle, Hai-Ling Li, Si-Ling Xu, Lu Liu, Dong-Dong Zhao, Wen-Liang Che
BACKGROUND: Pegylated interferon (pegIFN) in combination with ribavirin (RBV) has successfully improved the rate of sustained virological response (SVR) in chronic hepatitis C virus (HCV) infected individuals, which reduces the progression of the chronic liver disease. However, the influence of combination therapy (pegIFN/RBV) on cardiac function has yielded ambiguous results. The present study aimed to evaluate the effects of combination therapy with pegIFN/RBV on cardiac function of HCV-infected individuals with SVR...
June 2018: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/29891039/the-relationship-between-vascular-endothelial-growth-factor-cis-and-trans-acting-genetic-variants-and-metabolic-syndrome
#13
Mohsen Azimi-Nezhad, Seyed Reza Mirhafez, Maria G Stathopoulou, Helena Murray, Ndeye Coumba Ndiaye, Abdollah Bahrami, Abdoreza Varasteh, Amir Avan, Amelie Bonnefond, Marc Rancier, Hassan Mehrad-Majd, Bernard Herbeth, John Lamont, Peter Fitzgerald, Gordon A Ferns, Sophie Visvikis-Siest, Majid Ghayour-Mobarhan
BACKGROUND: We have investigated the association between 4 cis- and trans-genetic variants (rs6921438, rs4416670, rs6993770 and rs10738760) of the vascular endothelial growth factor (VEGF) gene and metabolic syndrome (MetS) and its individual components in an Iranian population. MATERIAL & METHOD: Three hundred and thirty-six subjects were enrolled and MetS was defined according to the International-Diabetes-Federation (IDF) criteria. Genotyping was carried out in all the individuals for 4 VEGF genetic variants using an assay based on a combination of multiplex polymerase chain reaction and biochip array hybridization...
June 2018: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/29891038/association-of-substance-use-with-hospitalization-and-virologic-suppression-in-a-southern-academic-hiv-clinic
#14
Celensia Tolson, Lauren E Richey, Yujing Zhao, Jeffrey E Korte, Kathleen Brady, Louise Haynes, Eric G Meissner
BACKGROUND: Persons with HIV infection who do not achieve virologic suppression contribute significantly to the ongoing HIV epidemic and have an increased risk of clinical sequelae related to immunosuppression. The extent to which substance use and mental health diagnoses affect HIV outcomes and the care continuum has not been previously assessed at the Medical University of South Carolina (MUSC), a large academic HIV clinic. METHODS: To address this knowledge gap and identify targets for intervention, we performed a retrospective chart review to examine associations of substance use and mental health diagnoses with hospitalization and virologic suppression...
June 2018: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/29891037/clinical-characteristics-and-outcomes-in-young-patients-with-st-segment-elevation-myocardial-infarction-after-primary-percutaneous-coronary-intervention
#15
Ming Gao, Waiou Zhao, Zhiguo Zhang, Ling Qin, Weihua Zhang, Yang Zheng
BACKGROUND: There are few published studies of ST-segment elevation myocardial infarction (STEMI) in younger individuals. The differences between these "younger" and "older" individuals may not be fully appreciated by clinicians. The aim of this study was to determine the reasons for the earlier presentation and help to identify strategies for prevention of recurrent myocardial infarction (MI) in younger patients. METHODS: The study population was a cohort of 2,419 consecutive STEMI patients who were treated with primary percutaneous coronary intervention...
June 2018: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/29891036/increased-cystatin-c-level-in-st-elevation-myocardial-infarction-predisposes-the-prognosis-of-angioplasty
#16
Guidong Shen, Hongmin Zhu, Hong Ding, Chaoyang Sun, Kun Zhou, Yan Fan, Tao Li, Min Men, Yuewu Chen, Qun Lu, Aiqun Ma
BACKGROUND: The study aimed to evaluate the prognostic value of cystatin C in ST-elevation acute myocardial infarction (STEMI) patients who underwent elective percutaneous coronary intervention (PCI). METHODS: A retrospective study was conducted on 664 STEMI patients from 7 centers who were treated with elective PCI. These patients were divided into 3 groups according their admission cystatin C levels as < 0.84, 0.84-1.03 and ≥1.04mg/L. The all-cause mortalities and the composite endpoints, including mortality, reinfarction, rehospitalization for heart failure and angina or repeat target vessel revascularization were observed for up to 5 years...
June 2018: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/29891035/antibiotic-timing-and-outcomes-in-sepsis
#17
Richard Y Kim, Alex M Ng, Annuradha K Persaud, Stephen P Furmanek, Yash N Kothari, John D Price, Timothy L Wiemken, Mohamed A Saad, Juan J Guardiola, Rodrigo S Cavallazzi
BACKGROUND: We evaluated the effect of time spent in the emergency department (ED) and process of care on mortality and length of hospital stay in patients with sepsis or septic shock. METHODS: An observational cohort study was conducted on 117 patients who came through the University of Louisville Hospital ED and subsequently were directly admitted to the intensive care unit (ICU). Variables of interest were time in the ED from triage to physical transport to the ICU, from triage to antibiotic(s) ordered, and from triage to antibiotic(s) administered...
June 2018: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/29891034/the-timing-of-antibiotic-administration-after-triage-in-the-emergency-department-may-not-be-straight-forward
#18
EDITORIAL
Steven Clum, Mark Rumbak
No abstract text is available yet for this article.
June 2018: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/29891033/quantitating-heart-damage-part-of-the-story
#19
EDITORIAL
L Julian Haywood
No abstract text is available yet for this article.
June 2018: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/29680156/macrophage-migration-inhibitory-factor-a-potential-target-for-diabetes-prevention
#20
EDITORIAL
Sri Prakash L Mokshagundam
No abstract text is available yet for this article.
June 2018: American Journal of the Medical Sciences
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